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Ptges3-ps prostaglandin E synthase 3, pseudogene [ Mus musculus (house mouse) ]

Gene ID: 100043508, updated on 8-Feb-2024

Summary

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Official Symbol
Ptges3-psprovided by MGI
Official Full Name
prostaglandin E synthase 3, pseudogeneprovided by MGI
Primary source
MGI:MGI:3704271
See related
AllianceGenome:MGI:3704271
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm9769
Summary
Orthologous to human PTGES3 (prostaglandin E synthase 3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
6 C3; 6 37.5 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (85820803..85822372)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (85843821..85845390)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene N-acetyltransferase 8 (GCN5-related) family member 5 Neighboring gene N-acetyltransferase 8 (GCN5-related) Neighboring gene STARR-seq mESC enhancer starr_16509 Neighboring gene predicted gene, 38847 Neighboring gene STARR-seq mESC enhancer starr_16510 Neighboring gene N-acetyltransferase 8 (GCN5-related) family member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA polymerase binding ISO
Inferred from Sequence Orthology
more info
  
enables Hsp90 protein binding ISO
Inferred from Sequence Orthology
more info
  
enables prostaglandin-E synthase activity ISO
Inferred from Sequence Orthology
more info
  
enables telomerase activity ISO
Inferred from Sequence Orthology
more info
  
enables unfolded protein binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in chaperone cofactor-dependent protein refolding ISO
Inferred from Sequence Orthology
more info
  
involved_in chaperone-mediated protein complex assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of phosphorylation ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of telomerase activity ISO
Inferred from Sequence Orthology
more info
  
involved_in prostaglandin biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
  
involved_in telomerase holoenzyme complex assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in telomere maintenance via telomerase ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of protein folding chaperone complex ISO
Inferred from Sequence Orthology
more info
  
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
  
part_of telomerase holoenzyme complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
prostaglandin E synthase 3-like
Names
predicted pseudogene 9769
telomerase binding protein, p23; telomerase binding protein p23

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    85820803..85822372
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036152432.1 → XP_036008325.1  prostaglandin E synthase 3-like

    Conserved Domains (1) summary
    cd00237
    Location:51 → 157
    p23; p23 binds heat shock protein (Hsp)90 and participates in the folding of a number of Hsp90 clients, including the progesterone receptor. p23 also has a passive chaperoning activity and in addition may participate in prostaglandin synthesis.
Nucleotide Protein Strain
Heading Accession and Version

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