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Zfp981 zinc finger protein 981 [ Mus musculus (house mouse) ]

Gene ID: 100041433, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp981provided by MGI
Official Full Name
zinc finger protein 981provided by MGI
Primary source
MGI:MGI:3700965
See related
Ensembl:ENSMUSG00000056300 AllianceGenome:MGI:3700965
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm13247
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
4 E1; 4 78.3 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (146586457..146623852)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (146502000..146539395)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr4:145746825-145747126 Neighboring gene STARR-positive B cell enhancer ABC_E6263 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145737763-145738064 Neighboring gene zinc finger protein 992 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145736397-145736698 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145733036-145733337 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145715582-145715883 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145714381-145714682 Neighboring gene carnitine deficiency-associated gene expressed in ventricle 3 pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr4:145711415-145711716 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145707828-145708129 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145704476-145704777 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145703390-145703691 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145702225-145702525 Neighboring gene STARR-seq mESC enhancer starr_12041 Neighboring gene RIKEN cDNA 1700095A21 gene Neighboring gene STARR-positive B cell enhancer mm9_chr4:145660367-145660668 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145657520-145657821 Neighboring gene predicted gene 13237 Neighboring gene protein phosphatase 2, regulatory subunit B', alpha pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
  2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC100041433

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001243138.1 → NP_001230067.1  uncharacterized protein LOC100041433

    See identical proteins and their annotated locations for NP_001230067.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL627077
    Consensus CDS
    CCDS57311.1
    UniProtKB/TrEMBL
    A2A8V7
    Related
    ENSMUSP00000101361.3, ENSMUST00000105735.9
    Conserved Domains (5) summary
    smart00349
    Location:13 → 55
    KRAB; krueppel associated box
    COG5048
    Location:45 → 410
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:269 → 289
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box
    pfam13465
    Location:309 → 334
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001243139.1 → NP_001230068.1  uncharacterized protein LOC100041433

    See identical proteins and their annotated locations for NP_001230068.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has a different 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL627077
    Consensus CDS
    CCDS57311.1
    UniProtKB/TrEMBL
    A2A8V7
    Related
    ENSMUSP00000136739.2, ENSMUST00000179175.3
    Conserved Domains (5) summary
    smart00349
    Location:13 → 55
    KRAB; krueppel associated box
    COG5048
    Location:45 → 410
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:269 → 289
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 52
    KRAB; KRAB box
    pfam13465
    Location:309 → 334
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    146586457..146623852
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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