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Lncenc1 long non-coding RNA, embryonic stem cells expressed 1 [ Mus musculus (house mouse) ]

Gene ID: 100039691, updated on 2-May-2024

Summary

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Official Symbol
Lncenc1provided by MGI
Official Full Name
long non-coding RNA, embryonic stem cells expressed 1provided by MGI
Primary source
MGI:MGI:3780541
See related
Ensembl:ENSMUSG00000078952 AllianceGenome:MGI:3780541
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm2373; Gm11019; Platr18; Lincenc1; linc-Enc1
Summary
Acts upstream of or within regulation of gene expression. Is expressed in brain. Orthologous to human LINC01157 (long intergenic non-protein coding RNA 1157). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
13 D1; 13 50.71 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (97571441..97641366)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (97434970..97497664)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33390 Neighboring gene STARR-seq mESC enhancer starr_35381 Neighboring gene STARR-seq mESC enhancer starr_35383 Neighboring gene predicted gene, 33447 Neighboring gene STARR-seq mESC enhancer starr_35388 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:98212351-98212677 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene 2379 Neighboring gene predicted gene, 41030

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A proinflammatory long noncoding RNA Lncenc1 regulates inflammasome activation in macrophage. Han Y, et al. Am J Physiol Lung Cell Mol Physiol, 2023 May 1. PMID 36880658, Free PMC Article
  2. LncRNA embryonic stem cells expressed 1 (Lncenc1) is identified as a novel regulator in neuropathic pain by interacting with EZH2 and downregulating the expression of Bai1 in mouse microglia. Zhang Z, et al. Exp Cell Res, 2021 Feb 1. PMID 33340495
  3. The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway. Sun Z, et al. Stem Cell Reports, 2018 Sep 11. PMID 30174313, Free PMC Article
  4. Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain. Goff LA, et al. Proc Natl Acad Sci U S A, 2015 Jun 2. PMID 26034286, Free PMC Article
  5. Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs. Lai KM, et al. PLoS One, 2015. PMID 25909911, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A proinflammatory long noncoding RNA Lncenc1 regulates inflammasome activation in macrophage.
    Title: A proinflammatory long noncoding RNA Lncenc1 regulates inflammasome activation in macrophage.
  2. LncRNA embryonic stem cells expressed 1 (Lncenc1) is identified as a novel regulator in neuropathic pain by interacting with EZH2 and downregulating the expression of Bai1 in mouse microglia.
    Title: LncRNA embryonic stem cells expressed 1 (Lncenc1) is identified as a novel regulator in neuropathic pain by interacting with EZH2 and downregulating the expression of Bai1 in mouse microglia.
  3. A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice.
    Title: A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Other Names

  • long intergenic non-coding RNA, embryonic stem cells expressed 1

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_110430.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript.
    Source sequence(s)
    AC124581
    Related
    ENSMUST00000179324.2

  2. NR_110431.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an internal exon, resulting in a shorter transcript, compared to variant 1.
    Source sequence(s)
    AC124581

  3. NR_110432.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two exons and contains an alternate 5' terminal exon, resulting in a shorter transcript, compared to variant 1.
    Source sequence(s)
    AC124581, CT030035
    Related
    ENSMUST00000109431.10

  4. NR_188726.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124581, CT030035

  5. NR_188727.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124581

  6. NR_188728.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC124581, CT030035

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    97571441..97641366
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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