POU5F1P5 POU class 5 homeobox 1 pseudogene 5 [Homo sapiens (human)] - Gene

Summary

Official Symbol: POU5F1P5provided by HGNC
Official Full Name: POU class 5 homeobox 1 pseudogene 5provided by HGNC
Primary source: HGNC:HGNC:33311
See related: AllianceGenome:HGNC:33311
Gene type: pseudo
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: Oct4-pg5
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Genomic context

Location:: 10q21.3

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	10	NC_000010.11 (68009947..68010883, complement)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	10	NC_060934.1 (68878715..68879651, complement)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	10	NC_000010.10 (69769704..69770640, complement)

Chromosome 10 - NC_000010.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

OCT4-pg5 was abnormally activated in endometrial carcinomas. Its overexpression enhanced cell proliferation and OCT4-PI3K/AKT-cyclin D1 signaling. OCT4-pg5 acts as an RNA sponge to protect OCT4 transcripts from miR-145 inhibition.
Title: OCT4 pseudogene 5 upregulates OCT4 expression to promote proliferation by competing with miR-145 in endometrial carcinoma.

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Other Names

POU domain class 5, transcription factor 1 pseudogene 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

NR_131184.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AL356741

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000010.11 Reference GRCh38.p14 Primary Assembly

Range

68009947..68010883 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

NC_060934.1 Alternate T2T-CHM13v2.0

Range

68878715..68879651 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NG_006104.6: Suppressed sequence

Description

NG_006104.6: This RefSeq was permanently suppressed because it is now thought that this gene is a transcribed pseudogene.