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Full record GDS4487

Ras/MEK inhibition effect on IFN-alpha treated cancer cell line: time course

Analysis of HT1080 cells treated with IFN-alpha, the Ras/MEK inhibitor U0126, or both for 6 or 12 hours. SKOV3 cells treated with IFN-alpha for 6 hours examined. HT1080 is moderately resistant to the anti-viral effects of IFN-alpha. MEK inhibition increases the sensitivity of HT1080 to IFN-alpha.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 4 agent, 2 cell line, 2 time sets
Platform:
GPL6244
Series:
GSE31019
30 Samples
Download data: CEL

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