Similar studies for GEO DataSets (Select 473) - GEO DataSets

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Items: 20

Select item 4731.

Muscle function and aging - female (HG-U133B)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (20-29 year old) and older (65-71 year old) women

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 age sets

Platform:: GPL97
Series:: GSE674
15 Samples

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DataSet

Accession:: GDS473

ID:: 473

Select item 2000006742.

Normal Muscle - Female , Effect of Age

(Submitter supplied) Healthy younger (20-29 yr) and older (65-71 yr) women donated vastus lateralis muscle under standard conditions. Keywords = muscle Keywords = aging Keywords: time-course

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS472 GDS473
Platforms:: GPL97 GPL96
30 Samples

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Series

Accession:: GSE674

ID:: 200000674

Select item 4723.

Muscle function and aging - female (HG-U133A)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (20-29 year old) and older (65-71 year old) women

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 age sets

Platform:: GPL96
Series:: GSE674
15 Samples

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DataSet

Accession:: GDS472

ID:: 472

Select item 2000003624.

Normal human muscle - U133 arrays

(Submitter supplied) vastus lateralis biopsies were obtained from healthy subjects, either young adults (20-29 yr old) or older (65-75 yr old) Keywords = muscle Keywords = aging Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS287 GDS288
Platforms:: GPL96 GPL97
30 Samples

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Series

Accession:: GSE362

ID:: 200000362

Select item 2885.

Muscle function and aging - male (HG-U133B)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 age sets

Platform:: GPL97
Series:: GSE362
15 Samples

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DataSet

Accession:: GDS288

ID:: 288

Select item 2876.

Muscle function and aging - male (HG-U133A)

Comparison of gene expression in vastus lateralis skeletal muscle biopsies in healthy young (21-27 year old) and older (67-75 year old) men

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 age sets

Platform:: GPL96
Series:: GSE362
15 Samples

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DataSet

Accession:: GDS287

ID:: 287

Select item 2000000177.

Young and old muscle comparison

(Submitter supplied) RNA was pooled from vastus lateralis biopsies obtained from 8 younger (21-24 yr) and 8 older (66-77 yr)men. Healthy subjects with no neuromuscular disease. Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by SAGE

Platform:: GPL4
2 Samples

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Series

Accession:: GSE17

ID:: 200000017

PubMed Similar studies

Select item 2000559248.

Regulation of skeletal muscle energy/nutrient-sensing pathways during metabolic adaptation to fasting in healthy humans

(Submitter supplied) The aim of the study was to investigate how short-term fasting affects whole-body energy homeostasis and skeletal muscle energy/nutrient-sensing pathways and transcriptome in humans. For this purpose, twelve young healthy men were studied during a 24-hour fast. Skeletal muscle biopsies were collected and analyzed at baseline and after 4, 10 and 24h of fasting. As expected, fasting induced a time-dependent decrease in plasma insulin and leptin levels, whereas levels of ketone bodies and free fatty acids increased. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5473
Platform:: GPL10558
48 Samples

Download data: TXT

Series

Accession:: GSE55924

ID:: 200055924

Select item 54739.

Short-term fasting effect on skeletal muscle: time course

Analysis of skeletal muscle biopsies collected at 1.5, 4, 10, and 24hr post-meal time from healthy young men subjected to a 24hr fast. Results provide insight into the molecular mechanisms underlying metabolic adaptation to fasting in healthy humans.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 12 individual, 4 time sets

Platform:: GPL10558
Series:: GSE55924
48 Samples

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DataSet

Accession:: GDS5473

ID:: 5473

Select item 20000176410.

Effect of Oxandrolone on Muscle in Duchenne Muscular Dystrophy

(Submitter supplied) Three subjects with Duchenne muscular dystrophy (8.3, 10.4, and 16.7 years old) were studied. Baseline studies included stable isotope infusion followed by gastrocnemius muscle biopsy to determine myosin heavy chain synthesis rates. RNA was isolated from the muscle biopsy as well. The subjects were then treated for 3 months with oxandrolone (a synthetic anabolic steroid, 0.1 mg/kg/day) and the studies repeated. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS1333 GDS1334
Platforms:: GPL96 GPL97
12 Samples

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Series

Accession:: GSE1764

ID:: 200001764

Select item 133411.

Duchenne Muscular Dystrophy response to oxandrolone (HG-U133B)

Analysis of gastrocnemius muscle biopsy specimens from Duchenne muscular dystrophy (DMD) patients before and after 3 months of treatment with 0.1mg/kg/day oxandrolone, a synthetic anabolic steroid. Results provide insight into mechanisms underlying the beneficial effect of oxandrolone in DMD.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 3 individual sets

Platform:: GPL97
Series:: GSE1764
6 Samples

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DataSet

Accession:: GDS1334

ID:: 1334

Select item 133312.

Duchenne Muscular Dystrophy response to oxandrolone (HG-U133A)

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 3 individual sets

Platform:: GPL96
Series:: GSE1764
6 Samples

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DataSet

Accession:: GDS1333

ID:: 1333

Select item 20000847913.

Resistance Exercise Reverses Aging in Human Skeletal Muscle

(Submitter supplied) Human aging is associated with skeletal muscle atrophy and functional impairment (sarcopenia). Multiple lines of evidence suggest that mitochondrial dysfunction is a major contributor to sarcopenia. We evaluated whether healthy aging was associated with a transcriptional profile reflecting mitochondrial impairment and whether resistance exercise could reverse this signature to that approximating a younger physiological age. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL2700
65 Samples

Download data: CSV

Series

Accession:: GSE8479

ID:: 200008479

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000035314.

Effect of age on skeletal muscle

(Submitter supplied) Comparison of gene expression in young soleus muscle (3-4 months) with old soleus muscle (30-31 months). Keywords: parallel sample

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platforms:: GPL85 GPL86 GPL87
296 Samples

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Series

Accession:: GSE353

ID:: 200000353

Select item 20006716015.

The effect of age on the skeletal muscle transcriptome during hypertrophy

(Submitter supplied) Transcriptome analysis of skeletal muscle during hypertrophic growth in aged mice Global gene expression patterns were determined from microarray results on day 1, 3, 5, 7, 10 and 14 during plantaris muscle hypertrophy induced by synergist ablation in old adult mice (25 months).

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6246
14 Samples

Download data: CEL, CHP

Series

Accession:: GSE67160

ID:: 200067160

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004709816.

Expression data during plantaris muscle hypertrophy induced by synergist ablation in young adult mice

(Submitter supplied) Global gene expression patterns were determined from microarray results on day 1, 3, 5, 7, 10 and 14 during plantaris muscle hypertrophy induced by synergist ablation in young adult mice (5 months).

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS4932
Platform:: GPL6246
14 Samples

Download data: CEL

Series

Accession:: GSE47098

ID:: 200047098

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 493217.

Synergist ablation effect on young adult plantaris muscle: time course

Analysis of right and left plantaris muscle from young males (5 months old) subjected to 1, 3, 5, 7, 10 and 14 days of synergist ablation surgery to induce hypertrophy. Results provide insight into the molecular response of young skeletal muscle to mechanical overload induced by synergist ablation.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 stress, 7 time, 2 tissue sets

Platform:: GPL6246
Series:: GSE47098
14 Samples

Download data: CEL

DataSet

Accession:: GDS4932

ID:: 4932

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20003871818.

Sex and aging effect on skeletal muscle transcriptome in humans

(Submitter supplied) The aim of this investigation was to develop a global view of muscle transcriptional differences between older men and women and with aging for each sex.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4858
Platform:: GPL570
22 Samples

Download data: CEL

Series

Accession:: GSE38718

ID:: 200038718

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 485819.

Skeletal muscles from men and women of various ages

Analysis of biceps brachii muscles from men and women 19 to 28 or 65 to 76 years of age. Results provide insight into the influence of gender on age-related changes in the molecular properties of the skeletal muscle.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 age, 2 gender sets

Platform:: GPL570
Series:: GSE38718
22 Samples

Download data: CEL

DataSet

Accession:: GDS4858

ID:: 4858

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20013662720.

Gene regulation in gastrocnemius muscle of denervated mouse with HDAC4 inducible knockout or class IIa HDAC inhibitior NVS-HD1 treatment

(Submitter supplied) Our class IIa HDAC inhibitor, NVS-HD1, inhibited HDAC4 with less than 1 nM potency while exhibiting >200 fold selectivity on class IIa HDACs compared to class I (HDAC1, 3, 8) and class IIb (HDAC6) HDACs, making it the most potent and selective class IIa HDAC inhibitor reported so far. We tested the efficacy of NVS-HD1 in the mouse denervation model, either alone or on the genetic background of HDAC4 whole-body inducible knockout (HDAC4 iRKO). more...