GEO DataSets

Analysis of 5 different brain regions from 6 inbred strains. Results provide insight into strain-specific and brain region-specific patterns of gene expression.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 6 strain, 5 tissue sets

Platform:

GPL1261

Series:

GSE4734

61 Samples

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(Submitter supplied) Gene expression patterns were determined from five brain regions (bed nucleus of the stria terminalis, hippocampus, hypothalamus, periaqueductal gray, and pituitary gland) in six mouse strains (129S6/SvEvTac, A/J, C57BL/6J, C3H/HeJ, DBA/2J, and FVB/NJ). At least two replicate samples per brain region/strain were analyzed using Affymetrix Mouse Genome 430 2.0 arrays. Keywords: mouse strain and brain region comparison

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS2917

Platform:

GPL1261

61 Samples

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(Submitter supplied) Background Haplotype association mapping is a recently developed method that can be used to identify expression Quantitative Trait Loci (eQTLs). The underlying genomic structure of the haplotype can be defined by single nucleotide polymorphisms (SNPs), variable number tandem repeats (VNTRs) and copy number variations (CNVs). Microarray genotyping platforms are able to interrogate all three genomic polymorphisms simultaneously. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

5 Samples

Download data: CEL, TXT

(Submitter supplied) This study aimed to perform gene expression quantitative trait locus mapping (eQTL) in the livers of a panel of 36 laboratory inbred strains. Mice were dosed with a saline solution by oral gavage and sacrificed at 24 hours. Livers were removed at sacrifice, RNA was extracted and gene expression was assayed using the Agilent G4121A array. Keywords: eQTL, mouse, liver

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL6466

73 Samples

Download data: TXT

(Submitter supplied) Genome-wide gene expression profiling has been extensively used to generate biological hypotheses based on differential expression. Recently, many studies have used microarrays to measure gene expression levels across genetic mapping populations. These gene expression phenotypes have been used for genome-wide association analyses, an analysis referred to as expression QTL (eQTL) mapping. Here, eQTL analysis was performed in fat issue from 28 inbred strains of mice. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1073

28 Samples

Download data: CEL

(Submitter supplied) The purpose of this experiment was to determine the expression traits in animals from F2 intercross of inbred strains C57BL/6J, C3H/HeJ. (N=309, 164 males and 145 females).

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2510

292 Samples

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(Submitter supplied) The purpose of this experiment was to determine the expression traits in animals from F2 intercross of inbred strains C57BL/6J, C3H/HeJ. (N=309, 164 males and 145 females).

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2510

285 Samples

Download data

(Submitter supplied) The purpose of this experiment was to determine the expression traits in animals from F2 intercross of inbred strains C57BL/6J, C3H/HeJ. (N=309, 164 males and 145 females).

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2510

302 Samples

Download data

(Submitter supplied) The purpose of this experiment was to determine the expression traits in animals from F2 intercross of inbred strains C57BL/6J, C3H/HeJ. (N=309, 164 males and 145 females).

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2510

295 Samples

Download data: TXT

(Submitter supplied) The (C57BL/6J X C3H/HeJ)F2 intercross consists of 334 animals of both sexes. All are ApoE null and received a high fat Western diet from 8-24 weeks of age.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2510

319 Samples

Download data

(Submitter supplied) The (C57BL/6J X C3H/HeJ)F2 intercross consists of 334 animals of both sexes. All are ApoE null and received a high fat Western diet from 8-24 weeks of age.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2510

249 Samples

Download data

(Submitter supplied) The (C57BL/6J X C3H/HeJ)F2 intercross consists of 334 animals of both sexes. All are ApoE null and received a high fat Western diet from 8-24 weeks of age.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2510

295 Samples

Download data

(Submitter supplied) The (C57BL/6J X C3H/HeJ)F2 intercross consists of 334 animals of both sexes. All are ApoE null and received a high fat Western diet from 8-24 weeks of age.

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL2510

311 Samples

Download data

(Submitter supplied) Comparison of mRNA accumulation in segregating doubled haploid barley lines ****[PLEXdb(http://www.plexdb.org) has submitted this series at GEO on behalf of the original contributor, . The equivalent experiment is BB21 at PLEXdb.]

Organism:

Hordeum vulgare

Type:

Expression profiling by array

Platform:

GPL1340

41 Samples

Download data: CEL

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Toxoplasma gondii; synthetic construct

Type:

Expression profiling by array

Platforms:

GPL6851 GPL6863

52 Samples

Download data: GPR

(Submitter supplied) Toxoplasma gondii is an intracellular parasite with a significant impact on human health, especially in cases where individuals are immunocompromised (e.g., due to HIV/AIDS). In Europe and North America only a few clonal genotypes appear to be responsible for the vast majority of Toxoplasma infections, and these clonotypes have been intensely studied to identify strain-specific phenotypes that may play a role in the manifestation of more severe disease. more...

Organism:

Toxoplasma gondii; synthetic construct

Type:

Expression profiling by array

Platform:

GPL6863

28 Samples

Download data: GPR

(Submitter supplied) Toxoplasma gondii is an intracellular parasite with a significant impact on human health, especially in cases where individuals are immunocompromised (e.g., due to HIV/AIDS). In Europe and North America only a few clonal genotypes appear to be responsible for the vast majority of Toxoplasma infections, and these clonotypes have been intensely studied to identify strain-specific phenotypes that may play a role in the manifestation of more severe disease. more...

Organism:

Toxoplasma gondii; synthetic construct

Type:

Expression profiling by array

Platform:

GPL6851

24 Samples

Download data: GPR

(Submitter supplied) Heterosis (hybrid vigor) refers to the superior performance of hybrid progeny relative to their parents. Although widely exploited in agriculture, the mechanisms responsible for heterosis are not well understood. As a monoecious organism, a given maize plant can be used as both male and female parents of crosses. Regardless of the cross direction, the maize inbred lines B73 and Mo17 produce hybrids that substantially out-perform their parents. more...

Organism:

Zea mays

Type:

Expression profiling by array; Expression profiling by high throughput sequencing

4 related Platforms

533 Samples

Download data: TXT

(Submitter supplied) BACKGROUND: The genetics of transcript-level variation is an exciting field that has recently given rise to many studies. Genetical genomics studies have mainly focused on cell lines, blood cells or adipose tissues, from human clinical samples or mice inbred lines. Few eQTL studies have focused on animal tissues sampled from outbred populations to reflect natural genetic variation of gene expression levels in animals. more...

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL3729

57 Samples

Download data: TXT

(Submitter supplied) Survey of gene expression in ten common inbred strains of laboratory mouse. Seven brain regions examined: amygdala, basal ganglia, cerebellum, frontal cortex, hippocampus, cingulate cortex, olfactory bulb. Keywords: Genetic background and brain region Sample data tables were removed because the ID_REF identifiers did not match the platform IDs

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL891

213 Samples

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