GEO DataSets

Generation of a molecular signature for metastatic hepatocellular carcinoma (HCC) and identification of genes relevant to metastasis and patient survival. Osteopontin identified as molecular marker for defining metastatic potential.

Organism:

Homo sapiens

Type:

Expression profiling by array, log ratio, 3 disease state, 40 individual, 3 tissue sets

Platform:

GPL257

Series:

GSE364

87 Samples

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(Submitter supplied) Comparison of hepatocellular carcinoma with non-cancerous liver tissue. Keywords: repeat sample

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS274

Platform:

GPL257

87 Samples

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(Submitter supplied) Transcription profiling of pair-matched tumor and adjacent liver tissues from 56 HCC patients were performed using cDNA microarray. Keywords: Disease state analysis

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL8177

112 Samples

Download data: TXT

(Submitter supplied) To identify HGF/Met regulated genes, we performed expression microarray analysis after inducible activation of Met receptor in primary cultures of hepatocytes established from wild-type control (Alb-Cre +/-) and Met conditional knockout mice (Alb-Cre +/-; Met Fl/Fl). Keywords: time series design

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS3148

Platform:

GPL1536

60 Samples

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Analysis of Met-deficient hepatocytes treated with HGF for up to 24 hours. HGF/Met signaling controls invasive growth and metastasis in a variety of cancers, including hepatocellular carcinoma. Results identify a Met-dependent gene expression signature that may help elucidate the oncogenic process.

Organism:

Mus musculus

Type:

Expression profiling by array, log2 ratio, 2 agent, 2 genotype/variation, 5 time sets

Platform:

GPL1536

Series:

GSE4451

60 Samples

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(Submitter supplied) To investigate the role of viral and host factors in HDV-associated HCC we carried out an integrated clinicopathological and gene expression study of tissue specimens and laser microdissected hepatocytes obtained at the time of liver transplantation from livers with HDV-HCC, HDV-cirrhosis without HCC, HCV-HCC and HBV-HCC. References to GSM series of HDV and HBV livers, already deposited in GEO, are included in this series. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

307 Samples

Download data: CEL, TXT

(Submitter supplied) To investigate the role of viral and host factors in HDV-related HCC we analyzed the serum, tissue specimens and laser microdissected hepatocytes obtained at the time of liver transplantation from five patients with HDV-HCC. Livers of seven patients with HDV-cirrhosis without HCC were also analyzed. We carried out an integrated clinicopathological analysis and gene expression profiling,

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

74 Samples

Download data: CEL

(Submitter supplied) We performed gene expression profiling of hepatocellular carcinoma (HCC), cholangiocarcinoma (CC), and mixed type of combined HCC and CC (CHC). In comparison of the profiles, a novel class of HCC expressing CC-like traits was identified.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL571

90 Samples

Download data: CEL