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Links from GEO DataSets

Items: 20

1.
Full record GDS1816

High-grade gliomas (HG-U133B)

Analysis of high-grade glioma (HGGs) samples from cases of WHO grade III and IV astrocytomas. Results classify HGGs into molecular subclasses with prognostic value that predict survival and disease progression. The molecular subclasses resemble key stages of neurogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 cell type, 4 disease state, 6 other, 2 specimen sets
Platform:
GPL97
Series:
GSE4271
100 Samples
Download data: CEL, EXP
2.

Molecular subclasses of high-grade glioma: prognosis, disease progression, and neurogenesis

(Submitter supplied) Novel prognostic subclasses of high-grade astrocytoma are identified and discovered to resemble stages in neurogenesis. One tumor class displaying neuronal lineage markers shows longer survival, while two tumor classes enriched for neural stem cell markers display equally short survival. Poor prognosis subclasses exhibit either markers of proliferation or of angiogenesis and mesenchyme. Analysis of gene expression data is described in Phillips et al., Cancer Cell, 2006. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS1815 GDS1816
Platforms:
GPL96 GPL97
200 Samples
Download data: CEL, EXP
Series
Accession:
GSE4271
ID:
200004271
3.
Full record GDS1815

High-grade gliomas (HG-U133A)

Analysis of high-grade glioma (HGGs) samples from cases of WHO grade III and IV astrocytomas. Results classify HGGs into molecular subclasses with prognostic value that predict survival and disease progression. The molecular subclasses resemble key stages of neurogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 cell type, 4 disease state, 6 other, 2 specimen sets
Platform:
GPL96
Series:
GSE4271
100 Samples
Download data: CEL, EXP
4.

HOXA9 transcriptomic analysis in GBM cell lines (U87MG, U251 and primary GBML18) and in immortalized human astrocytes (hTERT/E6/E7)

(Submitter supplied) Assess gene expression patterns upon HOXA9 ectopic expression in U87MG GBM cell line and hTERT/E6/E7 immortalized human astrocytes, and HOXA9 silencing in U251 and GBML18 GBM cell lines.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6480
28 Samples
Download data: TXT
Series
Accession:
GSE56517
ID:
200056517
5.

Expression profiles for paediatric brain tumours

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL6947 GPL8179
137 Samples
Download data
Series
Accession:
GSE42658
ID:
200042658
6.

Gene expression profiles for paediatric brain tumours

(Submitter supplied) In this study, we screened a cohort of 57 paediatric brain tumours, with a wide range of pathologies to identify gene expression profiles
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6947
73 Samples
Download data: TXT
Series
Accession:
GSE42656
ID:
200042656
7.

Gene Set Enrichment Analysis reveals lineage relationships between mouse and human gliomas and identifies stem cells and PNET as distinct entities

(Submitter supplied) Murine and human genome-wide microarray expression profiles (including GSE19404) were compared using Partek and Gene Set Enrichment Analysis (GSEA) in order to identify similarities. A murine PNET-like tumour by morphology was found to resemble human ATRT, whereas experimental glioma resembled a particular human glioblastoma subclass.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6096
33 Samples
Download data: CEL
Series
Accession:
GSE42515
ID:
200042515
8.

Gene expression analysis of primitive neuroectodermal tumors

(Submitter supplied) Central nervous system primitive neuroectodermal tumors (CNS PNET) and medulloblastomas are both embryonal tumors that predominantly occur in children. We used microarrays to analyse a cohort of CNS PNETs and medulloblastomas to identify gene expression related to tumor subgroups.
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4838
Platform:
GPL570
24 Samples
Download data: CEL
Series
Accession:
GSE19404
ID:
200019404
9.
Full record GDS4838

Central nervous system primitive neuroectodermal tumors

Analysis of central nervous system primitive neuroectodermal tumors (CNS PNET). CNS PNETs are embryonal tumors that occur predominantly in children. Results provide insight into the molecular mechanisms underlying CNS PNET pathogenesis.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 5 disease state sets
Platform:
GPL570
Series:
GSE19404
24 Samples
Download data: CEL
10.

miR-34a targets PDGFRA in proneural malignant glioma

(Submitter supplied) To identify potential targets of miR-34a, we performed transcriptional profiling on proneural TS543 GBM cells, focusing on mRNAs whose levels decreased in response to miR-34a transfection as compared to control oligonucleotide.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6947
6 Samples
Download data
Series
Accession:
GSE34242
ID:
200034242
11.

Expression and copy number data from five primary human glioblastomas

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome variation profiling by genome tiling array
Platforms:
GPL15648 GPL9128
11 Samples
Download data: CEL, TXT
Series
Accession:
GSE49810
ID:
200049810
12.

Copy number data from five primary human glioblastomas (frozen surgical resection)

(Submitter supplied) DNA hypomethylation could lead to activation of alternate promoters in GBM. We profiled DNA methylation and H3K4me3 genome-wide, and also performed expression and copy number analysis on the same samples In this dataset, we include all array CGH copy number data obtained for five GBMs. We used estimated copy number to normalize sequencing-based methylation data.
Organism:
Homo sapiens
Type:
Genome variation profiling by genome tiling array
Platform:
GPL9128
5 Samples
Download data: TXT
Series
Accession:
GSE49808
ID:
200049808
13.

Expression data from five primary human glioblastomas (frozen surgical resection) and one non-neoplastic adult brain (frozen autopsy tissue)

(Submitter supplied) DNA hypomethylation could lead to activation of alternate promoters in GBM. We profiled DNA methylation and H3K4me3 genome-wide, and also performed expression and copy number analysis on the same samples In this dataset, we include all expression data obtained for five GBMs and one normal brain. We identified loci with concurrent DNA hypomethylation and H3K4me3 in GBM, and analyzed expression of the nearest gene in the same sample using these data
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL15648
6 Samples
Download data: CEL
Series
Accession:
GSE49412
ID:
200049412
14.

TMEFF2 treated cancer cells and gastric cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL16951 GPL10332
12 Samples
Download data: GPR, TXT
Series
Accession:
GSE49052
ID:
200049052
15.

Gene expression outcome for gastric cancer patients

(Submitter supplied) The gene expression of the three cancer patients who had operation were compared with the genes of the three normal cases.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10332
6 Samples
Download data: TXT
Series
Accession:
GSE49051
ID:
200049051
16.

Gene expression-based, six individualized outcomes for cancer cells treated by TMEFF2 adenovirus and 2837 genes changes after treatment.

(Submitter supplied) The genes expression changes after the adenovirus treatment for 36 hours
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL16951
6 Samples
Download data: GPR
Series
Accession:
GSE49049
ID:
200049049
17.

PDGF Engages an E2F-USP1 Signaling Pathway to Support ID2-mediated Survival of Proneural Glioma Cells.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL19441
12 Samples
Download data
Series
Accession:
GSE77424
ID:
200077424
18.

PDGF Engages an E2F-USP1 Signaling Pathway to Support ID2-mediated Survival of Proneural Glioma Cells.

(Submitter supplied) Identification of critical survival determinants of PDGF-driven proneural glioma. Results provided information about the genes and pathways that are regulated by PDGF signaling in PDGF-driven proneural glioma and led to the assessment of the importance of the USP1-ID2 axis in proneural glioma.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL19441
6 Samples
Download data: TXT
Series
Accession:
GSE77423
ID:
200077423
19.

PDGF Engages an E2F-USP1 Signaling Pathway to Support ID2-mediated Survival of Proneural Glioma Cells.

(Submitter supplied) Identification of critical survival determinants of PDGF-driven proneural glioma. Results provided information about the genes and pathways that are regulated by PDGF signaling in PDGF-driven proneural glioma and led to the assessment of the importance of the USP1-ID2 axis in proneural glioma.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL19441
6 Samples
Download data: TXT
Series
Accession:
GSE77419
ID:
200077419
20.

Expression profiling of primary glioma samples

(Submitter supplied) Background: Signaling by receptor tyrosine kinases (RTK) is frequently dysregulated in gliomas. Inter-individual variability in the causes for dysregulated RTK signaling may have hampered the efficacy of targeted therapies. Using gene expression modules around key regulators in the RAS-RAF-MEK-MAPK cascade and in the phosphatidylinositol 3-kinase-AKT pathways, we developed a “RMPA” clustering scheme to distinguish gliomas with varying extents of RTK signaling. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6244
22 Samples
Download data: CEL
Series
Accession:
GSE74462
ID:
200074462
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