pfam09730: BicD (this model, PSSM-Id:370639 is obsolete and has been replaced by 462863)
Microtubule-associated protein Bicaudal-D
BicD proteins consist of three coiled-coiled domains and are involved in dynein-mediated minus end-directed transport from the Golgi apparatus to the endoplasmic reticulum (ER). For full functioning they bind with GSK-3beta pfam05350 to maintain the anchoring of microtubules to the centromere. It appears that amino-acid residues 437-617 of BicD and the kinase activity of GSK-3 are necessary for the formation of a complex between BicD and GSK-3beta in intact cells.
Jiyao W et al.(2023). "The conserved domain database in 2023.",