Conserved Protein Domain Family
TIP41
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pfam04176: TIP41 (this model, PSSM-Id:398031 is obsolete and has been replaced by 461208)
TIP41-like family
The TOR signalling pathway activates a cell-growth program in response to nutrients. TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway.
Links
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Statistics
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PSSM-Id: 398031
Aligned: 135 rows
Threshold Bit Score: 183.852
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EFN57235      64 FGDNYLHLTHEASGTTISFTARDALQgwlddtsgaaaagssispaAAPAAGSAAPAHaa--------------------- 122 Chlorella varia...
EIM19777      45 FLDSFVELRDNDSDFKISFNTRDALRgvsk-----------knelRVSYADHWANSRqteess--------------tik 99  Wallemia mellic...
XP_009268839  45 FLSSGVEVLDTDSGFKLSFNARDALRgvsk-----------qnelRVSYADHWRSSRqpheas--------------tiq 99  Wallemia ichthy...
XP_009269441  48 YPHNQIRIAHKLSNFTLGFYARPALNlvdks---------gaeakRVAYALHEGTKLqlq-------------------l 99  Wallemia ichthy...
EKD00708     134 FGHNSLVLQHPLVT--LSFDTLGALRavpvgegw---eercgggvLVSMADAWKNRKvedva----------------ak 192 Trichosporon as...
Q5KA94        98 asryiaVSTEARVN--LSFKTLDALAgvatgegw---edrvgggvLVSMAEKWGKNKswattestslpaagvfdvpvpsk 172 Cryptococcus ne...
EGO02100      57 FGSNYLSLEHVPSDWKLTFDTHSALKavkkgef-----eegdggvKVGYADAWLKSRtdpgsnlp----------mpktv 121 Serpula lacryma...
XP_003036636  60 FGGNFLLLEHRPSGWKYSFTCEDALRgvkkddd-----angkgmiKVNYADAWMKSRlpmpk----------------ta 118 Schizophyllum c...
ESK95136      58 FGRNILTLHHRRSGWRYTFSVEDALKavkrgel-----epgdggvKVNYADAWLKSRtspssllp----------mpetv 122 Moniliophthora ...
CCA72822      56 FGHNLIRLKHRESGWEYQFDTLHALQhvkngpl-----edgdgavKVRYADEWLKSRtdpnsqtp----------lpqtv 120 Serendipita ind...

EFN57235     123 qtLEYDWTYTTAYAGTVntgsggaagaagsdppkaaappasapagaagaaagaaagaaadgpcaggpTGAGRWEATTA-- 200 Chlorella varia...
EIM19777     100 psQPWDWTYTTRYNGSTsnvfst----------------------------------------------snnvnDT---- 129 Wallemia mellic...
XP_009268839 100 psQPWDWTYSTTYSGST---------------------------------------------------------ESERah 122 Wallemia ichthy...
XP_009269441 100 pdKNYDWTYTTTYSGSStrsfentpytsntatp------------------lldddnnvdhstggnsNHDYDNNHSHH-- 159 Wallemia ichthy...
EKD00708     193 pvRPHDWTFSTCFNGST---------------------------------------------------------SSSSep 215 Trichosporon as...
Q5KA94       173 pvKPHDWTYSTCYAGSV---------------------------------------------------------AGPStf 195 Cryptococcus ne...
EGO02100     122 ptkPYDWTYTTTYAGHY---------------------------------------------------------PASGte 144 Serpula lacryma...
XP_003036636 119 qtrPFDWTFTTTYKGHR---------------------------------------------------------LTSDdd 141 Schizophyllum c...
ESK95136     123 ptkPYDWTYTTIYTGHT---------------------------------------------------------ETDSrl 145 Moniliophthora ...
CCA72822     121 ptkPYDWTYTTMYEGHI---------------------------------------------------------SNEEgl 143 Serendipita ind...

EFN57235     201 ---------------------------------------------QVNRALLT-SRDP----ILYYDELALYESELDDHG 230 Chlorella varia...
EIM19777     130 ----------------------------------------------IPIDKLSdTNQP----ILFYDDVQLYEDELGDNG 159 Wallemia mellic...
XP_009268839 123 wqpi------------------------------------ptttpVIPIDKLSdTTQP----ILFYDDVQLYEDELGDNG 162 Wallemia ichthy...
XP_009269441 160 ------------------------------------------------------DSDP----TAIRNTITFFQDSMDGAG 181 Wallemia ichthy...
EKD00708     216 tadasrlt---------------------------aqqftpsdthAIPLQLLA-RQDPvldrILFYDDVPLYEDELHDHG 267 Trichosporon as...
Q5KA94       196 ep---------------------------------------ssthSLPLSLLA-RQDPvldqILYYEDVPLYEDELHDNG 235 Cryptococcus ne...
EGO02100     145 plsdlpssspi----------------------pwdvadpeqpshSIPLSELT-RPDP----IMFYAEIPLFEDELHDNG 197 Serpula lacryma...
XP_003036636 142 wpaapsyaddgaasdaendepappkprpasaefrwqpadptnpshAIPLAELT-RPDP----IVFYAEIPLFEDELHDNG 216 Schizophyllum c...
ESK95136     146 eeatpfipt-------------------------whpsdpenpsqQIPLSELT-RPDP----ILFYAEIPLFEDELHDNG 195 Moniliophthora ...
CCA72822     144 rypfi---------------------------------ktqdplhAIPMAELQ-RHDP----ILFYAQTLLFEDELHDNG 185 Serendipita ind...

EFN57235     231 SSRLALKVRVMPRCWYVLLRFWLRVDHVMVRLRETRLFCQFD---SPegtaTVLREVQVRY 288 Chlorella variabilis
EIM19777     160 QVGLNVKIRVMPFGWFILQRLFLRVDKVLFRMFDVRVYHEFN---SG----VVIRESTGLE 213 Wallemia mellicola CBS 633.66
XP_009268839 163 QVGLNVKIRVMPFAWFILQRFFLRVDDVLFRMYDVRVYHDFS---GN----VVSRECAGWE 216 Wallemia ichthyophaga EXF-994
XP_009269441 182 YTTLTATLRVDDDGFQVLQRHYVRIDRILFRMYETTFTHKFG---TW----KIEKRCKGWE 235 Wallemia ichthyophaga EXF-994
EKD00708     268 GSELNVRVRVMPHAFFVLARLFVRVDAVVFRIFDTRVFHSFG---SN----EVVRESSGME 321 Trichosporon asahii var. asahii CB...
Q5KA94       236 ESILNARIRVMPHSFFILARLFVRVDNVLFRIYDVRIYHAFG---SD----EIIREVSGME 289 Cryptococcus neoformans
EGO02100     198 SSSLLVRIRVMPTCIFILSRFILRVDNVLFRTHDTRIYHAFS---STt--pLVIRQISGWE 253 Serpula lacrymans var. lacrymans S7.3
XP_003036636 217 ASSLLVRIRVMPACIFILARFTLRVDNVLFRTYDTRIYSSHApgtNGk--tVVVRESGGWE 275 Schizophyllum commune H4-8
ESK95136     196 SSGLLVRIRVMPTCIFILARFTLRVDNVLFRTFDTRIYHSFA---SNp--pTVVRETCGWE 251 Moniliophthora roreri MCA 2997
CCA72822     186 SSSLLVRLRVMPGCIFLLSRFTLRVDQVLFRAFDTRIYHSFS---SSp--pLVIKEVIGLE 241 Serendipita indica DSM 11827
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