pfam10280: Med11 (this model, PSSM-Id:402068 is obsolete and has been replaced by 463042)
Mediator complex protein
Mediator is a large, modular protein complex that is conserved from yeast to human and conveys regulatory signals from DNA-binding transcription factors to RNA polymerase II. Not only are the polypeptides conserved but the structural organisation is also largely conserved. One or two subunits are either fungal or vertebral specific but Med11 is one of the subunits that is conserved from fungi to humans. Med11 appears to be necessary for the full and successful assembly of the core head sub-region.
Jiyao W et al.(2023). "The conserved domain database in 2023.",