Conserved Protein Domain Family
IL15

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pfam02372: IL15 
Interleukin 15
Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological functions, including stimulation and maintenance of cellular immune responses. Structurally these proteins are short-chain 4-helical cytokines.
Statistics
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PSSM-Id: 308146
Aligned: 8 rows
Threshold Bit Score: 136.497
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAF33206   5 VLIFSCISVALLMTTAYgasLSpekleilpALIKDLEILEESKNKIHVV--LYT-PNEIK-ECSQQTLQCYLEEM-VMLK 79 
Q95253    33 VFILGCISAGLPKTEAT---WQ--------HVISDLKKIEDLIRSIHMDatLYT-ESDAHpNCKVTAMKCFLLELrVILQ 100 pig
Q9XSJ6    33 VFILGCISAGLPKTEAN---WQ--------SVIHDLKTIEHLIQSMHMDatLYT-ESDAHpNCKVTALQCFLLELrVILH 100 sheep
Q75SZ9    33 VFVWGCISAGLPKTEAS---WH--------DVIYDLKRIENLIQSIHIDatLYT-ESDVHpNCKITAMKCFLLELrVILH 100 domestic guinea pig
O97687    33 VFILSCINAGLPKTEAN---WQ--------DVISDLKIIDKIIQSLHIDatLYT-ESDVHpNCKVTAMKCFLLELhVISL 100 domestic cat
AAG02253  54 iFFL-C--AYVPKTEANhckWS--------DVLKDLELIK---TSEDIDvsLYTaNTYEDiECQEPVMRCFFLEMkVILH 119
O73883     5 VLIFGCISVAMLMTTAYgasLSsakrkplqTLIKDLEILENIKNKIHLE--LYT-PTETQ-ECTQQTLQCYLGEV-VTLK 79  chicken
Q8JFF4     4 VLIFSCLSVLMLMTTAYgapLSekdn-tlkTLIKDLENLGTSMNGIDLE--LYT-PNDTK-ECSWQTLQCYLKEI-VTLE 77  mallard
AAF33206  80 KEieDEPEIKNEFKNALQNIKKNLHRlkDLSPTGGECKICEANDKKNFPDFLQQLTNL 137
Q95253   101 ES--RNSDISDTVENLIILANSSLSS--IEYKTESGCKECEELEEKNINEFLKSFIHI 154 pig
Q9XSJ6   101 ES--KNAAIYEIIENLTMLADRNLSS--IENKTELGCKECEELEKKSIKEFLKSFVHI 154 sheep
Q75SZ9   101 ES--RNEDIHETITNLIILANSSLNS--NGNVTESGCKECEELEEKSIAEFLQSFVHI 154 domestic guinea pig
O97687   101 ES--KNETIHQTVENIIILANSGLSS--NRNITETGCKECEELEEKNIKEFLQSFVHI 154 domestic cat
AAG02253 120 ECgiKKCSRKHDVWNILKNGNARFATyqLNSTTSKKCKECEEYEEKNFTEFIQSFVKV 177
O73883    80 KEteDDTEIKEEFVTAIQNIEKNLKSltGLNHTGSECKICEANNKKKFPDFLHELTNF 137 chicken
Q8JFF4    78 EEieDEDEIEDEKVSSVRNIKMNLQKlmDLIPPGTGCNICEA-NANNFPEFRQELTNf 134 mallard
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