Conserved Protein Domain Family
DUF647
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pfam04884: DUF647 (this model, PSSM-Id:398514 is obsolete and has been replaced by 428173)
Vitamin B6 photo-protection and homoeostasis
In plants, this domain plays a role in auxin-transport, plant growth and development and appears to be expressed by all cells in the plant as well as in plastids. The family has been shown to play a role in vitamin B6 photo-protection and homoeostasis in plants.
Links
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Statistics
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PSSM-Id: 398514
Aligned: 65 rows
Threshold Bit Score: 195.482
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_003835510  44 QDAKGYAQRVLDVFLPAGYPHSVTEDYIQYQIYDSLQAFSSSIASMLASRAVLEGklrfqlfrvhvwidvvqsrsfsqsi 123 Leptosphaeria m...
Q017Q6       107 RERAVGVPELRAVFLPSGFPQTVSADYADWLRWHLTSLLFRDVIEIMSAQSLLVA------------------------- 161 Ostreococcus tauri
XP_002873007 107 TNTLWLPDVVKDFVFPTGFPASVSDDYLDYMLWQFPTNVTGWICNVLVTSSLLKA------------------------- 161 Arabidopsis lyr...
XP_015622248  92 EANSSIPRAIKDFVLPAGFPGSVSDDYLEYMLWQLPTNVTGWICHTLVTSTLLKA------------------------- 146 Japanese rice
Q381S4       152 RRNESLLQRLHLFGMPAGYPDSCGEGFRRYFLLSLCSSFVSSFASSIGYQSILNG------------------------- 206 Trypanosoma brucei
XP_001467882  21 QHRETVSNRIRLFGMPKGFPDTTAAGFQRFFYLSLTSSFVSNFASSIGYQSLLSG------------------------- 75  Leishmania infa...
EEC48020      17 KELSKTGFELIQHFLPAQFPASVAPGYAQFCGFCFLASVSGSAGMVLSTQTLLLA------------------------- 71  Phaeodactylum t...
Q67YT8       110 KLIRLTSSAAKDFFLPK----QVSDNYISYVKWKFLHRVFSSALQVLATQAMFRA------------------------- 160 thale cress
XP_003058643 161 RRAERTRRRVVDAFLPC--ANAVTPDYWAYAKFRFAQRVASSCITVFATQQMLQA------------------------- 213 Micromonas pusi...
XP_001419164   7 DAARRCVERAQHALLPE--PSSVTNDYWEYAKFRFAQRIASSCISVFATQQMLTA------------------------- 59  Ostreococcus lu...

XP_003835510 124 crygvnsvpasglwgglgaarldrpfrnhvpflpvaacgkiadehpctfinrlagVGV--GDAN-------ASPTAALLL 194 Leptosphaeria m...
Q017Q6       162 -------------------------------------------------------LGV--GSTPg------ALPLTAAAK 178 Ostreococcus tauri
XP_002873007 162 -------------------------------------------------------VGV--GSFSgtsaaatAAASAAAIR 184 Arabidopsis lyr...
XP_015622248 147 -------------------------------------------------------VGV--GSFTgt----sAAASAAAIR 165 Japanese rice
Q381S4       207 -----------------------------------------------------------------------FLLASSPQL 215 Trypanosoma brucei
XP_001467882  76 -----------------------------------------------------------------------FFLGSSPQL 84  Leishmania infa...
EEC48020      72 -------------------------------------------------------IGVvgNAHS-------ASVMAGALN 89  Phaeodactylum t...
Q67YT8       161 -------------------------------------------------------IGI--GQSR-------SLASSAAFN 176 thale cress
XP_003058643 214 -------------------------------------------------------VGL--GATR-------RLPAAAAVN 229 Micromonas pusi...
XP_001419164  60 -------------------------------------------------------VGL--GASR-------TLPAAAAVN 75  Ostreococcus lu...

XP_003835510 195 SVLQDSMGRTATILFADRL--GTAF------------------------------------------------------- 217 Leptosphaeria m...
Q017Q6       179 WVLKDGVGSFATLLAGAFG--GRWY------------------------------------------------------- 201 Ostreococcus tauri
XP_002873007 185 WVSKDGIGALGRLLIGGRF--GSLF------------------------------------------------------- 207 Arabidopsis lyr...
XP_015622248 166 WVSKDGIGAFGRLLIGGRF--GTLF------------------------------------------------------- 188 Japanese rice
Q381S4       216 WMLKDLAPALAAAYLANRV---ISY------------------------------------------------------- 237 Trypanosoma brucei
XP_001467882  85 WMLKDLVPALFAAYMANKV---VSY------------------------------------------------------- 106 Leishmania infa...
EEC48020      90 WVLKDGIGQLGGVIFASRMgeTRRF------------------------------------------------------- 114 Phaeodactylum t...
Q67YT8       177 WILKDGLGRLSRCIYTASL--ASAF------------------------------------------------------- 199 thale cress
XP_003058643 230 WVLKDGLGRLGKLSVATNF--GREFgafytlvpirprwrgerrslrtfpggslahhtvsipalgafqlhltpfdstptfa 307 Micromonas pusi...
XP_001419164  76 WVLKDGLGRLGKLSVAANF--GRTF------------------------------------------------------- 98  Ostreococcus lu...

XP_003835510 218 ------EPECKMYRFTADILNDTGMVLECLSPAF-PkPIRVCVLSCSSVLRSLCGVCAGS-AKASLSAHFARKGNLGEVN 289 Leptosphaeria m...
Q017Q6       202 ------DEDPKRWWAVSNALEDVARAIELVTPAA-P-GLFLPLAASATFVRAAALTGRGSlMNGTFMQHFGRNNNLGDIR 273 Ostreococcus tauri
XP_002873007 208 ------DDDPKQWRMYADFIGSAGSFFDLATQLY-P-SQFLLLASTGNLAKAVARGLRDP-SFRVIQNHFAISGNLGEVA 278 Arabidopsis lyr...
XP_015622248 189 ------DDDPKKWRMYADFIGSAGSIFELITPLY-P-GYFLPLASLGNLAKAVGRGFRDP-SFRVIQNHFAESGNLGEVA 259 Japanese rice
Q381S4       238 ------ENRPKFWFVFSVALHNLSVIAEMIIPTTvP-NHLLAAAILTSCVRQSASLMFLV-TRASALQHFAISNNLAELT 309 Trypanosoma brucei
XP_001467882 107 ------ESRPKFWFVVSVFINNLTVISDMLIPSVlP-NHLLAAAIITSTVKQSSALMYFV-TRASALQHYAINNNLAELT 178 Leishmania infa...
EEC48020     115 ------DANPKKWRMMGALCLDSASLLDILSPFApS-AVVLPLACFANALKNIGYLTVGA-SRAALHQALTRAGNLGDVT 186 Phaeodactylum t...
Q67YT8       200 ------DTNLKRVRFSTSVLFSLSIGVELMTPVF-P-QYFLLLASIANIAKQISLSCYLA-TGSAVHRSFAVADNLGEVS 270 thale cress
XP_003058643 308 cmkrpsDSDVKRFRFTSSVVYDCASLIEMITPFY-P-SKFLLLATIANVGKSVGITTANV-VRAPIQMSFALEENLAEIA 384 Micromonas pusi...
XP_001419164  99 ------DSDVKRFRFTSSVVYDASSFIEIITPYF-P-QHFLPLATVANIGKSVGITTANV-VRAPIQRTFILEENLAEVA 169 Ostreococcus lu...

XP_003835510 290 AKDSSQETVISLLGMLAGSVVVSWISSPMAt--------------wSTLIGLLAIHLATNYAAVRAVSMRCLNRQRANIL 355 Leptosphaeria m...
Q017Q6       274 AKLEVQGRWLALVALPVGIQVFQLVNAQASalhaegdelgaaaaafGGYGLVIGAHIFSCWQAARSLKFDSLNGFRLLRL 353 Ostreococcus tauri
XP_002873007 279 AKEEVWEVAAQLIGLGFGILIIDTPGLVKSfpf-----------vsLTWTSVRLVHLWLRYQSLAVLQFNTVNLKRARII 347 Arabidopsis lyr...
XP_015622248 260 AKEEVWEVGAQLLGLSIGVFIMDTSGIKSSypt-----------laLTWLGVRLLHLWFRYQSLSVLKFRTVNLKRARIL 328 Japanese rice
Q381S4       310 KKFNSFGMVIYTVSTALGIAYTSLVPSVTAq--------------lATVLMCCGANLAISHLSMCNIAFRILNETTLSVI 375 Trypanosoma brucei
XP_001467882 179 KKFNSFGMVSYTVATALGILYCTYIASFTVq--------------lITVAACCVTNMFLSSMSMMPITFRLLNFDTMKLL 244 Leishmania infa...
EEC48020     187 AKAGSQSIAAGLLGTGVGIGLSAAMGHDAGnf-------------vLGFCGLSLIHQLCNFAALQHVDLHHFNRHRLYLV 253 Phaeodactylum t...
Q67YT8       271 AKAQIQTVCFDNLGLLLAVLLNMLFQHNQRlqac---------lpfVLYPIFSTFDLLGIYQGLKHINLQTLTKDRLEII 341 thale cress
XP_003058643 385 AKTSAQQVLADNIGLALAVVATGWTGKIANprlrl-------avplLAFAPLASVDLYCIYRELKSVRLRTINKERGEII 457 Micromonas pusi...
XP_001419164 170 AKTSAQQVLADNIGLALAVGAAKAVSKVATvrpeir-----ralpvFAFGPLAALDLICIYKELKAVQLRTINKERAEII 244 Ostreococcus lu...

XP_003835510 356 FSRLLEHG 363 Leptosphaeria maculans JN3
Q017Q6       354 AEAYVASD 361 Ostreococcus tauri
XP_002873007 348 VESHVVHS 355 Arabidopsis lyrata subsp. lyrata
XP_015622248 329 VRSHVAKH 336 Japanese rice
Q381S4       376 LRFYMREe 383 Trypanosoma brucei
XP_001467882 245 LRAFILEk 252 Leishmania infantum JPCM5
EEC48020     254 LDHYLRHG 261 Phaeodactylum tricornutum CCAP 1055/1
Q67YT8       342 LERWIEFR 349 thale cress
XP_003058643 458 AAGFVETG 465 Micromonas pusilla CCMP1545
XP_001419164 245 AEAFVKER 252 Ostreococcus lucimarinus CCE9901
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