XP_011221063 46 QLLHFKTSLLEALEELRMRREAETQYEEQISKIIAETQELKWQKETLQNQKETLAKQHKEAMAAFKKQLQMKMCALEEEK 125 giant panda XP_003412181 26 QLLDFKTSLLEALEELRMRREAETQYEEHIGKIIVETQELKWQKETLQNQKETLAKQHEEAMAVFKKQLQMKMCALEEEK 105 African savan... XP_017201246 26 QLLDFKTSFLEALEELRMRREAETQYEEQIGKIIVEIQELKWQKESLQNQKETLVKQHKEAMAVFKKQFQMKMCALEEEK 105 rabbit EHB17868 27 QLLDFKTSLLEALEELRMRREAEIQYEEQIGKIIMETQELKWQKETLQNQKEALVKQHKEAMEVFKKQLQMKMYALEEEK 106 naked mole-rat Q8CDM4 27 QLLDFRTSLLEALEELRMRRKAETQYEEQIAKIILETQELKWQKEALQNQKEALIKQHKEAMGVLKNQLQMKMYALEEEK 106 house mouse XP_016154491 25 rLLDFKTNLLEAIEELRIRRETETNYEDQINKIVIEKQELEWQKETLQHQTDTLQQQNKEAMAAFKKQLQARMFAMEEEK 104 collared flyc... XP_003781586 27 QLLDFKTSLLEALEELRMRREAETQYEEQIAKIIVETQELKWQKETLQNQKETLAKQHEEAMAVFKKQLQMKMCALEEEK 106 small-eared g... XP_023612165 26 QLLDFRTSLLEALEELRIRREAEIQYEEQIGKIIVETQELKWQNETLQNQKETLTKQHKEAMAVFKKQLQMKMCALEEEK 105 little brown bat
XP_011221063 126 GKYQLAAEIKEKEIEGLKETLKALQVSKYSLQKKISEMEQKVQLHLLAKEDHQKQLNEIEKYYGTITGQFGLVKENHEKL 205 giant panda XP_003412181 106 GKYQLATEIKEKEIEGLKETLKALQVSKYSLQKKLSEMEQKVQLHFLAKEDHHKQLNEIEKYYAIITGQFGLVKENHEKL 185 African savan... XP_017201246 106 GKFQLATEIKEKEIEGLKETLKTLQVSNYSLQKKMSEMEQKVQLHLLAKEDYHKQLNEIEKYYTAITGQFGLVKENHEKL 185 rabbit EHB17868 107 GKYQLASEIKEKEIEGLKETLKELQVSKYSLQKKVSEMEQKVQFHLLAKEDYHKQLNEIEKYYATITNQFGLVKENHVKL 186 naked mole-rat Q8CDM4 107 GKYKLATEIKEKEIEGLKETLKTLQVSQYSLQKKVSEMEQKAHLYHLAKEDYHKQLNEIEKYYAAITNQFGLVRENHVKL 186 house mouse XP_016154491 105 GKYQLAAETKEKEIDGLKETLKALQISKYTLQKKLNEMDQKLQMHLTAKEEHHKKLNEVERCYATIASRFGVVKGVHGKL 184 collared flyc... XP_003781586 107 GKYQLATEVKEKEIEGLKETLKALQVSKYSLQKKVSEMEQKIQLHLLAKEDYHKQLSEMEKYYATITGQFGVVKENHEKL 186 small-eared g... XP_023612165 106 GKYQLATEIKEKEIEGLKETLKALQVSKYSLQKKVSEMEQKLQLQLLAKEDHQKQLNEIEKYYATITGQFGLVKESHGKL 185 little brown bat
XP_011221063 206 EQNVQEAIQLNKRLSALNKKQESEICSLKKELKKVTSDLIKSKVTCQHKMGEENIHLTIKEQKFQELQERLNMELELNKK 285 giant panda XP_003412181 186 ERNVQEAIQLNKRLSALNKKQEFELCSLKKELKKVTSDLIKSKVTCQYKMGEENTNLTIKERKFQELQERLNMELELNKK 265 African savan... XP_017201246 186 EQNVQEAIQVNKRLSALNKKQESEICSLKKELKRVSSDLIKSKVTCQYKMEEENINLTIKEQKFEELEERLNVELELNKK 265 rabbit EHB17868 187 DQNVQEAIQLNKRLSALNKKQESEICSLKKELKKAASDLIKSKVICQYKMKEENINLTIKEQKLEELQEKLSMELELNKK 266 naked mole-rat Q8CDM4 187 EQNVQEAIQLNKRLSTLNEKQESEIHSLKKELKKAASELIKSKVTCQHKMEEESIDLIIKEQKYEELQERLNMELEVNKK 266 house mouse XP_016154491 185 EHSVQEAIQHNKKLASVNKRQETEISNLKEELKKVTTDLIRSKVNSQYRVGEENINLAVKEKQFQELQQKIRMETAVSKK 264 collared flyc... XP_003781586 187 ERNVQEAIQLNKRLSALNKKQESEICSLKKELKNVASDLRKSKVTWQYKMGEENINLTMKEQKFQELQERLNMEFELNKK 266 small-eared g... XP_023612165 186 EQNVQEAIQLNKRLSALNKKQESELCSLKKELKKVTSDLIKSKVTWQHKMGEENINLTIKEQKIQELQERLNMELELNKK 265 little brown bat
XP_011221063 286 INEEIAHVQEEKKGIIISFQHMQQLLQHQTQVSTELEAKLKMLKENNQTLERDNELQREKVKENEEKFLNLRNEHEKALG 365 giant panda XP_003412181 266 INEEISRIQEEKQNVIISFQHMQQLLQQQTQANAEMKAELKVLKENNQTLERDNELQREKVRENEEKFLNLQNEHEEAQG 345 African savan... XP_017201246 266 INEEITYIQEEKQGIIISFQHMQQLLQQQIQANTEIEAEFKILKENNQTLERDNELQREKVKENEEKFLNLQNEHEKALG 345 rabbit EHB17868 267 INEEIIHIQEEKQDIFTSFQHMQQLLQQQTQANNEMDAELKALKEKNQTLERDNELQRKKVRENKEKFLNLQNEHEKAVG 346 naked mole-rat Q8CDM4 267 INEEITHIQEEKQDIIISFQHMQQLLQQETQANTEIDAELKVLRENNQTLERDNELQREKVKENEEKFLSLEKEHERALG 346 house mouse XP_016154491 265 VQEENTHIKEEKLEILSSLQCVQELLQRITQANVRMESELNALKEDYQALERDNELQREKAKENEEKFLNLQNEHEKALK 344 collared flyc... XP_003781586 267 INEEVTHIQEEKQDIIISFQHMQQLLQQQIQANTEMEAELKALKENNQTLERDNELQREKVKENEEKFLNLQNEHEKALG 346 small-eared g... XP_023612165 266 ITEEITHIQEEKQDIIISFQHMQQLLQQQTQANTELEAELKVQRENNQTLERDNELQREKLKENEEKFLNLQNEHEKALR 345 little brown bat
XP_011221063 366 TWKKHVEELNGEINEIKNELSSLNETHIKLQEHYNELCDQKKLEEDkKFQNIP-E------VNTKTS-ELSMEKSENIII 437 giant panda XP_003412181 346 TWKKHVEELNGEINEIKNELSSLKETHIKLQEHYNKIYDQKKFEEDkKFQNVP-E------VSNEHS-RMSAEKSEDTTI 417 African savan... XP_017201246 346 TWKRHVEELTEEINEVKNELSLLKETHIKLQEHHNKFCEQRKFEEDkKFQNAP-E------VNNENC-EMLTEKSENTII 417 rabbit EHB17868 347 TWKRHIE-LNREINEIKDEFSSLKETHIKLQEQHNKFWSQKKLEEDkKFQNVP-E------INNENH-EI-TENSGKAII 416 naked mole-rat Q8CDM4 347 TWKKHVEELSGEMNVIKNELSSLRETHAKLQEHYNKLCEQKKTEEYkKFQNVP-E------LNNENSdELTRKKSENIIT 419 house mouse XP_016154491 345 TWKNDEENMRREIQTIKNELNSLKELHRHLEDYHPPQGNQ----HSeHVENLQmQspaqpiPTNVSG-QEHSKDSEILAI 419 collared flyc... XP_003781586 347 TWKRHVEELNGEINEMKDELSLLKETHIKLQEHYDKLCNQKKFEED-KFQNVP-E------VNNENS-EMSTEKLENPVI 417 small-eared g... XP_023612165 346 TGGKH---------------------------------------------NLP-E------VNTENS-DMSMGKLQN-II 371 little brown bat
XP_011221063 438 QKYn--------------SGQEIK-KDTLSFHS---DTNYRe-kEKKEGPFIEGGIIEDLQLLEKNTKNEIDPAISQAEN 498 giant panda XP_003412181 418 LTYn--------------SGQEIReENSMNFCS---DTEYR---EKKEGPPKEEIIIEDLQLLEKSCKNEIITTVPQDEN 477 African savan... XP_017201246 418 QKYn--------------FEQEKReENTESFSSyagDKETQq--EKKKCLPIEETVIKDLQLFEKNFK-KIDTAVSQDET 480 rabbit EHB17868 417 QKFn------------------SReENTKGFCS---YTEYRekdVMKESLAT-EVTVEDVQRFEKSFKNETDTSIPQDKG 474 naked mole-rat Q8CDM4 420 QKYn--------------SGPEIWgKNTKSFCL---DTEYRe--EEKKDLPVGKT-AEDLQPFEISAKSEINTMVSQDRN 479 house mouse XP_016154491 420 QKEnefmqsgiskcgncgNEEETEvKTTRDKSS---STEELk-tEQNP------------QVLENSFKDEINVASPRELK 483 collared flyc... XP_003781586 418 QKY---------------SEQEIGkENTEHFCS---DTRFReevEKKKGPSVEEIIIEDLQVLEKTFKNGMDTTVSQNKN 479 small-eared g... XP_023612165 372 QKYn--------------S----ReENKVSFCL---DTEYRe-nEKKKGPLTEEIIIEDIQHTEKISKNEIDPSVPQDEK 429 little brown bat
XP_011221063 499 QSETSLSKTLSTEKELISQGQT--LNVTDFRKAVTSEIKDKVGSGKDNGCTEFKSPNGSFLVADRSTETGKIHLGSTEGL 576 giant panda XP_003412181 478 QSEISLSKVLCTDKEVISQGQT--LNVPDFRKSITTEIKDKLCLEKDNGCTEFQSPTSLILVADTSIETKMIHLESMGGL 555 African savan... XP_017201246 481 PSEISLTNTLYIDKKVISLEKT--LNVTDCRKSVTTEIKDKMCLEKDNVCTEDKLPNNPSLVVDPAEETEKVHLEITD-- 556 rabbit EHB17868 475 QCGLSLSKPPCLGKDTISQ-QT--GSVTDPRKPAATETEDRLDLEKDSGCTEFKPPNNLCLV------------EGAEGS 539 naked mole-rat Q8CDM4 480 QSGMSPHRVLCLDKDATDQEQT--SDVTDSRKSVTVEVKDKLCLEKASGCSEFKSLNNFFLVVDESLETEMVRLEGTEGL 557 house mouse XP_016154491 484 QREACPRNTLCTDTDLTAQGHTseMHVTGGREAEDAGTAHRTLPDDSNANLDQKPLDSTEPLAAQHTQTRKDFLGSAERK 563 collared flyc... XP_003781586 480 QSEISLTKTHSRGKEVISQGQT--LNATDIRKSVTTEIKDVMCSEKDDGPSEFKTPNHPFLVVDSAKETEKICLERTERL 557 small-eared g... XP_023612165 430 QSEISVSKTLCIEKELISQGQT--LNVTDFRKAATTEIKDKMGLERDNESPEFKSPNNSFLEADISIETDSIHLERTEGF 507 little brown bat
XP_011221063 577 H--LHHA--DVHPEVENTRPS-NTTLSEta-----yQT---NQKKDVSEDEPFK-RFRLLPGIQENATDKeiTKTDQTKP 642 giant panda XP_003412181 556 D--SHHP--DVHLEAENHRSC-DSILND--------NT---NHSKDVSENEPFKqQFRLLPCTQKSTAERvmTNTDQTKA 619 African savan... XP_017201246 557 ---LAHA--DAHLEAEKNRTLfNSILNDmv-----hNT---SQNKDGSESEPFK-QFRLLLGTEENATKNeiTNSDQTKA 622 rabbit EHB17868 540 G--LHPA--CVRLESKDQRSSpDRTVSEta-----hNG---DHDKDVSENKPFRqQFRSHLGTKRGIT-------NRSKA 600 naked mole-rat Q8CDM4 558 G--LLHSggDIPLDTRSNKASsNGMSNEma-----hKR---NYNTDGSESNPFKqQSKLLPADLENATEKeiTNQDQTKA 627 house mouse XP_016154491 564 SvgADRK--NGSQETDTSKEElCGTADEsacakagaNSdtrQHNRSVLTPEAPKpQSEAVLCTERSALHErsTDSHQAKQ 641 collared flyc... XP_003781586 558 ElgLHHA--DIHLEVENNRTSfNSILNEta-----hNA---NHNKDVSENESFK-QFSSLLGTQENTTKK--ANSDQTKA 624 small-eared g... XP_023612165 508 D--VHCP--DLHLEVESNRISfNSVLNEma-----hST---NHKKDVSEQ-----RFRLLPETQENATKKtiTNSDQAKI 570 little brown bat
XP_011221063 643 DLGASLNINKNAVQ--CQKYSLQESSN----DKQCKTNqmQLLNKNSECSVSPFKQTSVLQQICN-------------DP 703 giant panda XP_003412181 620 ELDSSLDVKEKPVH--WEKCSLHNSSSvmldDKRCKTK--QLLRTQSECGILPLKQTSDFQQLCN-------------DT 682 African savan... XP_017201246 623 ALDSSLDVKKNSVH--CQKYSLQDSSSvmsdDKRCKIKqiQLLKENSEYSILPFKQTSYFQPVCS-------------DN 687 rabbit EHB17868 601 GLGSSLDAKMNPVQ--CEKYSFQDSRNarvsDKQCKMEhtQLLNKISEYSILPFKPTSSFPQVCN-------------DT 665 naked mole-rat Q8CDM4 628 GLDSFLDIKLNLDP--CKKHGLQDSSHvtldVKHQKIK--QMVREESQCSTEP----RSCYQLAS-------------KA 686 house mouse XP_016154491 642 LSFGILHSTKENSQaeYQKCSLLNSDNsv-gSGLHKAEk-tLNLSGLHRDKLPLEQTQVDAEGRNddnvrnvnntgvlAI 719 collared flyc... XP_003781586 625 DLDSSLDVKKNPVL--CQKYSLQDSSNvlldDEQCKIKqiQLLNKKSECNPLLFKETSEFQQVCN-------------DT 689 small-eared g... XP_023612165 571 DLDSSLDEKKKPVQ--CQKYNLHDSSNvildDKQCKIEqiQLVNNKSECSTLPPQQTSDVQQICK-------------DT 635 little brown bat
XP_011221063 704 S------EKPELTIPSDTAANHPISSAAVSENLKVlLKNSDKNVNIMPMLMKPNSSPGEGTIWKNLnEMHTSQLKNCLGY 777 giant panda XP_003412181 683 S------EKAQLNIPCDTASSYPISYAAFSDNLKL-LENSDKKVSIVPMLVKPNSSPGKRTTRKNL-DAQSSQFKDCLER 754 African savan... XP_017201246 688 P------EIPELTVPCDTVINHPISSAAFLDNLKVpLKNSDKNINIMPVLVKPNAGPEEGTMWKSMsDMKNSQLKNCLEY 761 rabbit EHB17868 666 L------EKPELTLPHDE-VNHLMSPAAPAENSKA-LPDSGNHIGIMPMLVTPNSNPRGRAVRKDRkDMQDSPFKSCLGC 737 naked mole-rat Q8CDM4 687 P------QKPGGTIACAAVVS-PLGPSASSDNKLTaLKKSENSINTLPTAAKPAPSPAERTTRTNTnDIQNSSLRNHLGA 759 house mouse XP_016154491 720 DavpetsAQHPPTVCCDN--------------ASAdAAAAKECRENKSLSGTFNLCPPKTGRGINAdDMHSKQPEQ--GG 783 collared flyc... XP_003781586 690 S------EKPELTVPCNTVIDHPFSSAAFSDNLKI-LKNSDKNVNSMSMLVKLNSSPGQRPMWKNMdDKSDSQFKNCSGY 762 small-eared g... XP_023612165 636 S------EKPGLTIPYDIAVEYPISSAVFSDNLKVfLKNSDTNVNMMPILVKPNSSPGKRAVCKNLnDSQ-SPFKDCLGD 708 little brown bat
XP_011221063 778 LE-NSATTSHLQVKNENIHTSEVKDMKTAVPTQTSTEIQFSNK--ESQIDENQITDATKNDLFLSVNVNERQHSLLN-TE 853 giant panda XP_003412181 755 LE-NNMTIPHLQIDNENIHASQPKDMKTAVYRKTSTEIQLSSK--DSQIDENQITEATKNDLFLLVNVNERQHSLLNnTE 831 African savan... XP_017201246 762 LEnSHVTISHLQVNDDSSHASQTGDVKTDARRKTSTETQFLNR----QIDENQITEATKPNHFLFVNVNERQHTLLNnTE 837 rabbit EHB17868 738 PG-KGVTTAPLHLNSEDTRASADTDLETALR-KTAMEVQFYS---ERKTDVSQITEATKHDPFLFVNVNERQHTLLNnTE 812 naked mole-rat Q8CDM4 760 SE-SSVSVSDFQVNQGDSHTSQAKGLKTVVPLTTSSEKQPPS--------ESQITETPKSGLSSLVDVTGRQCMWLNnRD 830 house mouse XP_016154491 784 AKpTGNAANRWASNAEAKSPVKADGLKIAQKPPPTDRACTDKLilCKNVNNGTQIHSIKTGHSLEI-DTSTNNTLLK--E 860 collared flyc... XP_003781586 763 LEnNNVTISHLQVNDENSHASQAKDVKTAVHPKTSTEIQFSNK--EIQIDKNQTTEATKNDLFLILNANERQHTLLNkTE 840 small-eared g... XP_023612165 709 LE-NSMNISQLQVNNENIHTSQAKDMKTAVHMKTSTEMQFSSK--ESHIDENQLTEATKNDLFLFVDVNERQHTLLNnTE 785 little brown bat
XP_011221063 854 KTESLNKIVSGKIYSEGQLEESCSFHIKPSGDLVNRSGRSAFDLSTSDKKTEKIPVYVNFLDPNPWSKVNQTESQTLSTS 933 giant panda XP_003412181 832 KTESLNDIVSEKIYIEGQLEESRSFHIKASGDSVNTSGMSAFDLSTSDKKTEKTPVYLNFLDPGTWSKVNQIESQTVSTS 911 African savan... XP_017201246 838 TTESLNDIVSGRMYSEGQLEESHSFPIKPSGDLVNTSGRSAFDLPTSDKKPEKTPVYTNFLNPSPWSKVNQIESQTVSTS 917 rabbit EHB17868 813 RTESLNDIVSGKLYSEGQQGESQSFHIKPSGNLVNRSGRASFDLPTSDRKTEKTPAYMNFLDPGPWSKVNQTAGQTVSPA 892 naked mole-rat Q8CDM4 831 KTEALNGILSGGTCHEGQLEEAHLSPATPSADSVSTSARSAFDLPSPD-KPEKTPGYIKFVPLSPWPKVNQT--KTVGTA 907 house mouse XP_016154491 861 KKGSLSSAVPGMKLAEGHLKESSSLPMRTSGNLVNISLRSSFDLSTSDKKAEKSPLYLNFLALSSCSRVNQVRGQAAWTS 940 collared flyc... XP_003781586 841 KTESLNDIVSEKMYSEGQLEESHSFHIKPSGDLVNRSGRSAFDPSTSDKKTEKTPVYMNISEPGPWSKVNQIENQIVDTS 920 small-eared g... XP_023612165 786 KTESLNDIVSGKIYSEGQLEESCSFHIKPSGDLVNRSGKSAFDLSTSDKKTEKTPVYVNFLDPSSWSKVNQNESQTVSTS 865 little brown bat
XP_011221063 934 TSSIP-LLKERPIGPSENKNIVSVTLCKN--DDDIRKD-TGPDTTSVNRVADTLNNSSIHPDPKGEPSEERNATAKTFYD 1009 giant panda XP_003412181 912 ASSILsSPKERPIGPSENKKIVSTTLGKNtgVDEVRKGvVRPDTTSINRVADTLNNSSIHPDPKGEPSEERNATAKTFYD 991 African savan... XP_017201246 918 TSSIPvLLKERPLGPSEHKKIISVTLGKN--VDDIKKD-IEPDTTSMNRVADTLNNWSIHPDPKGGPSEERNAIAKTFYD 994 rabbit EHB17868 893 MSSTPlLLKERPAGPSEHTKTTSVALCKNagVDDVRQD-AGPDAVRITGVADAVSTRSVRPDPERTPSEERNATAGMGPD 971 naked mole-rat Q8CDM4 908 TPSIPlFLKEKTVDLSGSRVITPVTFCKNvvLDDTRKN-IESDPTSNSRAADTMSNWSIHLDPKGQPREERNATAQTVYD 986 house mouse XP_016154491 941 ASKEPsLLKDKPA--LENTNIISKTQSQNlsENVDSEE-SGQGSSSLSRAANTLNASGIHREPQGEPSEEWNATAKAFYD 1017 collared flyc... XP_003781586 921 TSSISlLLKEKQINPSQNKNTISMSLCKNvdMDDNRKD-IGPDTTSINRVADTLNNWSIHPDPKGESSEERNATAKTFYD 999 small-eared g... XP_023612165 866 TSGIPlLLNERPIGPSENEKIVSMTLCKN-----VRKD-IGPDTTSINRVADTLNNSTIHPDPKGEPREERNATAKTSCD 939 little brown bat
XP_011221063 1010 SSFPTEH---------AKIKPVKSVLLQSHFQATKIK------DPtdvgassTGEDDWQSLVRNQINEIENFLSLENDNQ 1074 giant panda XP_003412181 992 SSFPTEH---------VKTKPLKSTLPRSPFQATEIK------DTtdlaasfTAEDDWQSLVTKQINEIEKLLSLESDNR 1056 African savan... XP_017201246 995 SSFPTEH---------VNTKPLSSALLLSHLQAIESK------DPtdf-aaaSGEDKWQSLVTNQINEIEKFLGLENDSQ 1058 rabbit EHB17868 972 SSVPTEH---------VKAEPRVPTVLQSHFQSIETQ------EPpdl-patPGED-WQSLVINQVTEIEKYLSLENDNQ 1034 naked mole-rat Q8CDM4 987 SSFPTEH---------VKAEPLISTVQQSHSQTVKVT------DSpdpltfsPGNNDWQSLVMNRLTEIEKLLSLESDNQ 1051 house mouse XP_016154491 1018 SSFPTEHvteglaafqNK--------QKSPHMTVSPA------RSekalkdeDSCSLQNSIIQNQTGGIEKLLNLERLHS 1083 collared flyc... XP_003781586 1000 SSFPTEH---------VETKSLKSTLLQSHFEAIKSKgtvdlaAP-------SGEDEWQRLITSHINEIEKFLNLENDNQ 1063 small-eared g... XP_023612165 940 SSFPTEH---------VKTQSLKSN-LQSHSQALKIK------DTtnltmssFGEGGWQSLITNQIKESEKFLSLENDNQ 1003 little brown bat
XP_011221063 1075 PKKRKAEEML 1084 giant panda XP_003412181 1057 PRKRKAEEML 1066 African savanna elephant XP_017201246 1059 PKKRKAEELI 1068 rabbit EHB17868 1035 PKVRKAEEML 1044 naked mole-rat Q8CDM4 1052 PKRRKVEEML 1061 house mouse XP_016154491 1084 ARKRKYEEgq 1093 collared flycatcher XP_003781586 1064 PKKRKAEEML 1073 small-eared galago XP_023612165 1004 SKKRKAEELL 1013 little brown bat
Jiyao W et al.(2023). "The conserved domain database in 2023.",