Conserved Protein Domain Family
AKAP95

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pfam04988: AKAP95 
A-kinase anchoring protein 95 (AKAP95)
A-kinase (or PKA)-anchoring protein AKAP95 is implicated in mitotic chromosome condensation by acting as a targeting molecule for the condensin complex. The protein contains two zinc fingers which are thought to mediate the binding of AKAP95 to DNA.
Statistics
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PSSM-Id: 461509
Aligned: 8 rows
Threshold Bit Score: 174.585
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
OCA42660      279 KEHFRYI--GGRLPKQQADFLEEYVRHKAKKTEERRVVVEDLSSTIQQiyrdQDLTQG-LGLEHFIKKVEAAHCAACDIF 355 
ELV13687     1128 KETLRFI--STKLPDKTVEFLQEYIVNRNKKIEKRRQELMEKESAKPK----PDPFKG-IGQEHFFKKIEAAHCLACDML 1200
A2CEZ5        286 RETLDYIrrQAKFDDKVISFLHDCMVNKFHKTVSNLHKLKFSCGRSKDe--wAKIMEG-VTEDDYMRRMEVVYCVACDVH 362  zebrafish
XP_015210883  328 KETLDYIqkQAKFDDGVINFLHESMVNKFRKTVSRKLNNNHPEQTLEEi--hKELMEG-VTEEDYMRKVEVIHCVACRAH 404 
XP_005997758  329 QETMDYIqkQTKFDKVVMEFLHECMVSKNKKTALRKQLSSQVEQVKTVq---KDVLEG-VTTEDHMSKVETVHCSACSTY 404 
1_pfamImport    1 QETLDHIqkQTKFDKVVMEFLHECMVNKFKKTSIRKQQTNNQTEVVKIi--eKDVMEGnLSYPYHFLNDFSSSVFPSSLL 78  
Q28F29        296 QEMLDHIqkQTKFDKPVMEFLHECIVNKFKKTAARRAQSLANEAAKALe---KDVMEG-VTPDDHMMKVETVHCSACSVY 371  tropical claw...
EDL89466       11 KEHFKYV--GTKLPKQTADFLQDYVTNKTKKTEELRKTVEDLDGLIQQiyrdQDLTQE-IAMEHFVKKVEAAHCAACDLF 87   Norway rat
OCA42660      356 IPMHFSALQRHLKSPLHNQNRRNTMEQSKKSALAVARSIL---NNKHIGQKLQRYIKGENPF 414 
ELV13687     1201 IPAQHQLLQRHLHSVDHNHNRRLAAEQFKKTSLHVAKSVL---NNRHIVKMLEKYLKGEDPF 1259
A2CEZ5        363 IPVLFSSVQQHLHSLTHLKSKVAYKEQLKRDSVVTAKAII---NNDNVKERYEKYMKGEDPF 421  zebrafish
XP_015210883  405 VPAVLSSVQQHLKSSDHQKNKVLYKEQLKKESVLTATSIL---NNPIVKARYEKYIKGEDPF 463 
XP_005997758  405 IPAVYSSVQQHLKSADHTKNKQVFNEQMKRECVLTATSIL---NNPIVKERYEKFAKGENPF 463 
1_pfamImport   79 IPS--------LEAYSYLKNKKTPKEQRKQNKYSTSTSFImleSGPTIKARXDSFIHGENPF 132 
Q28F29        372 VPALHSSVQLHLKSADHSKSKLAYKEQIKRESILTATSIL---NNPLVKARYELYLKGENPF 430  tropical clawed frog
EDL89466       88 IPMQFGIIQKHLKTMDHNRNRRLMMEQSKKSSLMVARSIL---NNKLISKKLERYLKGENPF 146  Norway rat
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