C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon
This domain is found at the C-terminus of several translation initiation factors, including the epsilon chain of eIF2b, where it has been found to catalyze the conversion of eIF2.GDP to its active eIF2.GTP form. The structure of the domain resembles that of a set of concatenated HEAT repeats.
Jiyao W et al.(2023). "The conserved domain database in 2023.",