1YZF


Conserved Protein Domain Family
Isoamyl_acetate_hydrolase_like

?
cd01838: Isoamyl_acetate_hydrolase_like 
Click on image for an interactive view with Cn3D
Isoamyl-acetate hydrolyzing esterase-like proteins. SGNH_hydrolase subfamily similar to the Saccharomyces cerevisiae IAH1. IAH1 may be the major esterase that hydrolyses isoamyl acetate in sake mash. The SGNH-family of hydrolases is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases
Statistics
?
PSSM-Id: 238876
Aligned: 36 rows
Threshold Bit Score: 170.511
Created: 30-Oct-2006
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
 
Conserved site includes 5 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:
  • Comment:by similarity to other members of this super-family
  • Comment:the active site resembles the typical Ser-His-Asp(Glu) triad from other serine hydrolases
  • Citation:PMID 7773790

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1              #                                          #                             
1YZF_A        3 KIVLFGDSITAGYLde----avSPVLVDLVkrdiaamgleevaVINAGMPGDTTEDGLKRLNKEVLie---------kpD 69  Enterococcus fae...
YP_173740     4 KLVCFGDSITAGHEglne-pmlTAFLKKKLppt--------veIINAGVSGDTTVQALARIVTDVIsh---------qpD 65  Bacillus clausii...
YP_192979     2 RLLLTGDSIIARKEgkne-phiNWNLKQVLpk---------leIENTAVSGINSGAFLARLNELVLsvk--------qcD 63  Lactobacillus ac...
ZP_00046777   2 KLLLTGDSIIARPEnhsi-pelNFQLQKFLsc----------nIYNTAISGINSGGLALSLPNLVFnqp--------kcN 62  Lactobacillus ga...
EAA37336      8 RIICLGDSISQYGWniae-ggfVGLLAEAYspk--------adVICRGLSGFTSEMLLHYMSNSNLldsldckgqstsiL 78  Giardia lamblia ...
YP_536426     3 NLVLFGDSITAGMTdgypspifSNEIRKYFpn---------ieILNRGVPGDHTDLALSRIQADILqs---------npD 64  Lactobacillus sa...
ZP_00235580   3 TLVCFGDSITADEMffngtprlTPRLREMFpn---------wnVVNAGVPGDNTFDALKRIKEDVLsh---------kpD 64  Bacillus cereus ...
AAQ15951      3 HILLLGDSLTEWGFec----gwASRLSNVYvrr--------adVINRGLCGYNTRWILSILKNDESrhhllp-ayaprpL 69  Trypanosoma brucei
NP_267879     8 KITIFGDSITNGFGmde--ggsSNIIARLIekne-----pklkVVLHGINGDDTYGGLLRLKYVLEee----------aD 70  Lactococcus lact...
BAA33369     39 RLTIIGDSITQKGFtpg---gyCAELMNFYqrr--------lrVDVWGFSGYTSRHVLRYLPEIPLeid--------stK 99  fission yeast
Feature 1               #                                                                       
1YZF_A       70 EVVIFFGANDASLdrn-----itVATFRENLETMIHEIg-----sEKVILITPPYADs------------------gRRP 121 Enterococcus fae...
YP_173740    66 LVTVLFGANDVAThkr-----veQDDFAHNIDKIASLIs-----pKKTILITPAPVDesl--------------eqnRTN 121 Bacillus clausii...
YP_192979    64 NLMILLGTNDLAThkq-----vpLNQFKQNMEFICSAVick-yypPHVLLISPPAVDeek--------------qhvRNN 123 Lactobacillus ac...
ZP_00046777  63 YLIILVGTNDLAThkq-----vpLRQFEKNLELIASSIiwl-yypEKVIFITPPAVDenk--------------qrvRNN 122 Lactobacillus ga...
EAA37336     79 YVTVCIGANDASSsaqnpiqsvhISKYRKNLVDILRFIhaagvpyDRIIVLAPPPIAdpaqhp--------clhekgKSP 150 Giardia lamblia ...
YP_536426    65 IVTIFFGTNDVTAeg------pdYQTFITNIKEMITLIg-----tQKCILITPGITGpsl--------------qdfYPN 119 Lactobacillus sa...
ZP_00235580  65 FVTVFLGTNDAVSfsq-----gsLQAYKENLEKIVNHIs-----sGKVLLISPAPVDeer--------------qhnRTN 120 Bacillus cereus ...
AAQ15951     70 FITLLLGSNDCATggq----avpLHEFKSNLRAIIDLVrkhaspvGGIFLMTPPPINvekwhkrlqrefgadpstcgRSL 145 Trypanosoma brucei
NP_267879    71 LNFIFFGANDASPyhl-----irPAEFRENLLKMISQLg-----vERTVLITPPFYNddep-------------thySKL 127 Lactococcus lact...
BAA33369    100 LLIVFLGTNDCQLtetg--ymcpVDEFKNNLLALTRPFp-----hSKIIIVSPGICTkd-----------------iCFK 155 fission yeast
Feature 1                                                             #  #                 
1YZF_A      122 ERPQTRIKELVKVAQEVGaa--hnLPVIDLYkamtvypg--------tdeflqaDGLHFSQVGYELLGALIVREI 186 Enterococcus faecalis
YP_173740   122 EDLKAYSDCIKEIAQRRD------CHFIDFFttffskpdy-----qwrlkgtmdDGLHFGEKGYDLLSDLIAEKI 185 Bacillus clausii KSM-K16
YP_192979   124 GLIKKYSETIQNIAEEYH------FEYADLCqamleagdi-----kkisqgiknDGLHFGDLGYEILAKLIVENL 187 Lactobacillus acidoph...
ZP_00046777 123 RLVMEYGNIVKKVASEYK------FSIIDLAskmqenknf-----peifngkknDGLHFGVNGYKLLANLIVKKI 186 Lactobacillus gasseri...
EAA37336    151 HLTEEYAQACLEIAKEVGar---pADVRLLWdkas---------------siwtDGLHMNRSGNRLLFQAIMDAC 207 Giardia lamblia ATCC ...
YP_536426   120 QKLSQYAQGLVTLAEELN------VACYDWHsiateye---------asellqaDDIHYSKKAYELLVQGLAPLI 179 Lactobacillus salivar...
ZP_00235580 121 EVLGQYADVVEEVAKETG------SYFLNLYaemiqerny-----ktfvenderDGLHFGPEGYEYVAKLIGEKL 184 Bacillus cereus G9241
AAQ15951    146 ERVLSYRDAVLQVGCVEKkah-ndVHVVDLYerflgkdaespnvakgpwcdylsDGLHFSETGGALVFDALMSAI 219 Trypanosoma brucei
NP_267879   128 SEVELFREVILNLGKEKS------LKVIDIFqimkssen--------pknllraDGLHFTSRAYELLVREILSVI 188 Lactococcus lactis su...
BAA33369    156 REQEPYVIAASETVNTLNkskansAGLINLYeitksyp---------tpellftDGLHFSSLGYSLLFNEIVATI 221 fission yeast

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap