Conserved Protein Domain Family
CysJ

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COG0369: CysJ 
Flavoprotein (flavin reductase) subunit CysJ of sulfite and N-hydroxylaminopurine reductases [Nucleotide transport and metabolism, Inorganic ion transport and metabolism]
Flavoprotein (flavin reductase) subunit CysJ of sulfite and N-hydroxylaminopurine reductases is part of the Pathway/BioSystem: Cysteine biosynthesis
Statistics
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PSSM-Id: 440138
Aligned: 246 rows
Threshold Bit Score: 447.287
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ADB42227      855 V---LDdestgvndetdAnr--asQTh-----------LPDQTs----tPAHRSR-RVLILYGSETGTAEHFAHRTARRL 913 
WP_012172043  545 DhldMLl----------ErrpevkGRfpvr-----teaPKTQGapl-avAQAGGR-PMRVLYGSNMGGCRDIALSLAQQA 607 
WP_015747835  467 TaspADv----------RpadgrtGTdmpga--taagsVAAGSvqpppnSDGHQQ-RLVVAASSDGGTARHLGYDLAHEA 533 
WP_013677914  456 eglfIQl----------RprpdrtTGtvvvapnaaqapAAKPKlrlapvGDRHGT-PLTVLFGSNLGTAEGIATRIAQDG 524 
WP_013952645  478 dgftVRa----------RrrrpheRIaaapv--agtaqAPQAGp----dVQGGGR-PLAVLCGSSLGTARELAEQVHAGA 540 
WP_015249791  457 dgftMKv----------RprgarvRTtvsavp-malsvAQETAeaaappPAGQGT-PLLILYGSNLGTAEGFAQRIAEDG 524 
WP_050981161  461 dnyfLKf----------KkrpgfkPVengpkvpasqslKLKGGk----qIYVQNKpLLYLAYGSNMGSSKKFIQQLAETA 526 
WP_015432709    1 --------------------------------------------------MPFFS-HIHIAYGSESGRAEQLAQQLQQQP 29  
WP_015674137    1 --------------------------------------------------MQSIS-HVHIAYGSESGNAEQLAQQLAQQP 29  
WP_080040673  444 DgftLRv----------RerraheRAvvaa-----lpeQESEQq----dIAVTGV-PLTVAYGSNLGTSSDIAERLAERA 503 
ADB42227      914 KRF--QPRVMALDEYAIEqLAQ-EDLLLVITSTFrEGHLPGNAQKFYARIQ-S--LPQGVCSGVSFSVMALGSTVY-PHF 986 
WP_012172043  608 GARgfAATVAELDEQVGQpWLT-DGPVVIVTSTY-NGTPPDNAARFAKWLE-T--APAGVCAGVRHAVLGCGNTQWhQTF 682 
WP_015747835  534 VDAgdAADGVELNALVDR-LPV-DRPLVVITASY-NGQPAAGARDFVSWLS-A--APDGAAHGVRFAVFGCGDHNWpTTY 607 
WP_013677914  525 ADRgfAVTLGALDDHVAD-LPK-EGGLVVVCASY-NGMPPDNAERFCAWIR-DaaTPADTAAGAAYAVFGCGNMDWaSTY 600 
WP_013952645  541 LAAgfDATLRDLDDVADA-LPT-TGLAVIIAATY-NGRAPDSARRLEALLD-SgaASGYRAEGLSVAVLGCGNSQW-PTY 615 
WP_015249791  525 RSLgfSVATAALDDATSD-LPR-EGALIIVTSSY-NGAPPDNAARFCDWLQ-KgnTGPAGFQGVRYAIFGCGDHNWsATY 600 
WP_050981161  527 QALgyQPSVHSLNETKAL-MAQnKGHYVIITASY-EGQPTHDAEEFVDWIV-E--QPEGSLDQVQYSLFGCGNSDWiHSY 601 
WP_015432709   30 CLAahPHSIASLNNTHLEqLPP-HTLLLIVTSSFgDGEAPANADQFANYLE-N--L---PACHISYAIFGLGDTSY-DKF 101 
WP_015674137   30 FLQpyQPTIATLNETELThLDP-QSLLLIITSSFgDGEPPENAEDFIENFLaN--S---TAYQGRYAIFGLGDVSY-DKF 102 
WP_080040673  504 GRAgfATTLTTLDDLTPP---A-EGLLIVVASSY-NGKAPDNAQRF-DALE-T--L--PDLSGVRLAVLGCGNTQW-PTY 571 
ADB42227      987 CAAGITLDRELARVGGNRVIMLHKGDEikGQADTFRQWLDLVARLLGEDPTsaDlSa---------tAEPDLTvsflape 1057
WP_012172043  683 QKFPKTIASGLAALGGTALLDEGTADAagDYEAAVEGWTAALWPALEAAFGg-AaGaavigsaeaaaEAPAVKvevvnfa 761 
WP_015747835  608 QAVPALIDRELVRIGGERLIDRGEGDSsgDLDGAFTRWSRSLWQALDAGRPg-PpRet-------rnPVGRYVasevgra 679 
WP_013677914  601 QAIPTMLDEQLERHGGRRVVPRGEGDArsDFDGQYEAWYATLWPAMTEALGl-EtAavg-----taaAGPRLTvtmtnrq 674 
WP_013952645  616 QAFPRRVYEFFTNAGASPLLPRGEADGngDFDQAAERWLASLWQALQAGDSv--gGpa--------hGTPPVRvqmrdva 685 
WP_015249791  601 QAIPKLIDQKLAAGGATRLHERGEGDAadDLDGQFQTWYGLLWTRIASALGl-QiKae-------akPRAAYRietvdtq 672 
WP_050981161  602 QAVPRKIDAQLKRLGAQPFLAPGEGNAkqNFFASFNQWHDELWPALAKSLGq-DaIsp--------iNKKSYKvqllhdw 672 
WP_015432709  102 CGYSKHLDHLLQCKHATAIIERVDADL--NYQAIFQQWLNLLIQALANPITpp-lShs--------lSVKVYA------- 163 
WP_015674137  103 CGYSRKLDQFFQTQQLPALIERVDADL--NYQEIFKLWLPLLEQALNKPEAap-lThk--------lSVKVYD------- 164 
WP_080040673  572 QDFPRRAYEKLTAAGAVPLIERGEADTdgDFDGDVSAWTARLWAALAEEYSa-DaGa----------AGPRYEmevlsea 640 
ADB42227     1058 qv---pqtaledraKQQPGCTvPVTANRELLKEvi----------------vGSRSTRFISLDISDIdATYETGDHVAIY 1118
WP_012172043  762 gaatgaaprtgtrlDQGAQLS-RIRVNRELLSPg------------------AQGSTRHIEIPLPAG-TSYAAGDHLAVF 821 
WP_015747835  680 -------sadgpadAFGMGEA-WVRSVTELTRRppdlgsdladipdagpgadGERVTMHLDVELDPA-VSYRPGDHLLVL 750 
WP_013677914  675 -------ttnpvvvSYRARPS-TVRVNRELNLDg------------------ADRSTRHVEIALAPG-TEYQTGDHLGVL 727 
WP_013952645  686 -------eirastlPANTQGF-TVLANTELVNDpsglwd--------fsreaPRTSTRDIRLRLPAG-VRYATGDHLAVY 748 
WP_015249791  673 -------vdlpfvaAYSAHRM-TVVASRELQQAgda--------------kaPERSTRHIELALPDG-VRYHTGNHLGVL 729 
WP_050981161  673 --------haqtlgENDFVRA-QLLSKKELVQQes----------------pFASSKIELQIEVPEG-QSYQTGGYIDIL 726 
WP_015432709  164 --------------ANQTYAA-QVLDIQQLAQ--------------------SAPAVFHLRLSLKESgIFYQAGDLIYLQ 208 
WP_015674137  165 --------------ENQTYAA-QVLEIQRLAQ--------------------SEPAVYHLRLSLENSgIFYQAGDLIYVQ 209 
WP_080040673  641 -------eirpavvSERAFPL-TVISNEELTGDpeglwd--------fsveaPRPGVRSIVARLPEG-VTYSAGDHVAVF 703 
ADB42227     1119 PLNLPAIVDRLVDRLNIDANAWFITplidgNraa---------vpGNhayptPVQVWKVLSEDVDLAIHEPfdELLGALL 1189
WP_012172043  822 PVNPPALVAAAAARCGLAPETQVLL-----TalhpdaaseaglpfGV-----PVSVGELLAEHVDLAGPVTr-RDLRAWA 890 
WP_015747835  751 PQNRQTIIWRAARTLKFDPSLVVEL-----Hatttve---tgvplGQ-----PTMMYDLLAGYCDLRAPATr-RGIDILA 816 
WP_013677914  728 PRNNVDLIRRVIARFKLDAGTYVTI-----Tptggsw---thlplDE-----PAPLLGVLGSCVELQDVAGr-SDIATLA 793 
WP_013952645  749 PQNQPGMVAALCERIGIDPDAIVTL-----Sasggaa---rglplGE-----ALSVRQLLTHFVELQDVVSr-QTLRLLS 814 
WP_015249791  730 PRNRGGAIRRVLERFRLDGDSQVII-----Rrddagk---snlplDR-----PIRLAELVGGYVELQDPATr-DQIRVLA 795 
WP_050981161  727 PQNSPATIQRVLRHFQMQHDPYIKL-----Eseeqsv--alklplDQ-----HIRLTDLLKYYVELQRPAGk-KWLEEVL 793 
WP_015432709  209 APNADSLLAEFCHWFNDSSA-------------------------------------KEVLQQKELRLLNK--NILRDVA 249 
WP_015674137  210 VQQQDDLLNMFVQWFGDDNA-------------------------------------AQQLRHKELRLLTK--NALRELA 250 
WP_080040673  704 AKNDPELVEWALRCLRVPREQVVRL-----Raagat-----hlpvDT-----PVTAGLLLTEFAELQEVATr-ADLEALA 767 
ADB42227     1190 KTAtsAiEkDkleDwLKTLKQPQeasedAVALKKHITDTfpTVADLLDAF-PSVR-LSFAQLLDVLPRQKPRLYSISSCS 1267
WP_012172043  891 QAAqcPpDrA---R-IAGWLSD--------FPSAVAEAKp-RMEDLLAQV-PSVQ-LDLAALLTVRPALKPRYYSISSSP 955 
WP_015747835  817 AHVdrDpArA---A-LLALTADD-----DAFAGGVLARRv-SLLDLATEY-PPDQpIPPALVVEAFPMLKPRPYSISSAP 885 
WP_013677914  794 ASAtdPaErE---A-LQALTTLDde-grARYRKTIAEPRv-TVLDLLDAY-PSCD-LSFAQFLDMLPPLRPRYYSISSAP 865 
WP_013952645  815 QSSrcPvTrQ---A-LQQLASDDa---eSGYAAQVAPRRl-GLADVLDRF-PAIE-LDLAGLLACTVPMRPRFYSIASSP 884 
WP_015249791  796 DKAlcPpDkA---R-LTPLVGDDea-slARYREEVFLPRr-SVLDLLELN-PSCV-LAFEEFLGMLPPLRPRYYSISSSP 867 
WP_050981161  794 AQTrcPfSaQ---G-LQQFI--------EQYESEVLQKNr-SLLSIIEQF-PGAK-IDLGQFISALPAMRPRTYSISSSV 858 
WP_015432709  250 KIC--D-S-T---E-LKALTKIAn----KKALEDYLYGH--DLLDLLRDFdPEHR-VSLQDLHALLPNLTARAYSISSCG 314 
WP_015674137  251 KIC--S-N-H---A-LKELLKIAn----KKALEQYLYGH--DLLDVLRDFdPQKI-ISLADLQAILPNLTARAYSISSCG 315 
WP_080040673  768 AHTacPwTkG---Q-LAELT--------ASYADEILAKRv-SPLALLERF-PAIE-LPLPVFLEMAGPIKPRYYSVSSSP 832 
ADB42227     1268 LVHPNEIHLTVGVVQVTTdAGK-TVAGLCSNYLAQLDPeqGATVRIAIRSS--GFRPPQLPQAPMLMVGAGTGLSPLVGF 1344
WP_012172043  956 LMSPDACALTVGVHQFTTaDGV-RHDGLCSSYLVSCGE--DAPVRVLVKDTgsTFHLPADPAVPLILVGPGTGLAPLRGF 1032
WP_015747835  886 IGEPNRVGITVGLVSGQAlSGHgRYYGVTSSYLVTLGA--GLRILARVADPgpQFHPPADPRTPLVMVCAGTGVAPFRGF 963 
WP_013677914  866 SES-ETCHITVGVLDVPArGRDgRFAGVCSTHLRSCET--DSTVFTFVRRPtiPFRPPENPHTPMIMVGAGTGMAPFRGF 942 
WP_013952645  885 LVSPDVATITVGTVWSAAlSGRgLFRGVASAWLQGLAP--GAMVAGAIRTPnpAFAPAADPATPMILIGPGTGIAPFRGF 962 
WP_015249791  868 LINERIASITVAVVRDASrSGLgLYEGVASNYLAELTE--GSEILGFVRGPgtPFQPPADPRTPMIMVGAGTGLAPFRGF 945 
WP_050981161  859 KQSTDKASLVVSCIKGAAwSGQgEYQGLASGYLSQLEE--GQLLWLRFSPNlpNFPAP-KSEDKLILIAAGTGIAPFRAF 935 
WP_015432709  315 QTHPEYVDLCVREVSYQL-GER-HYYGTASHYIAQCQA--GDFLPIFAKSNp-TFHLT-NKQIPIVMIGAGTGIAPYIGF 388 
WP_015674137  316 KTHPEYVDLCIRQVQYQL-ADR-QYYGTASCHLAQLQA--GDFVQIFAKANp-HFHLPEN-DKPIVMIGSGTGIAPYIGF 389 
WP_080040673  833 LADPGTVRLTVGLVEGPAwSGTgTYQGMCSAYLAGLKE--GEVFYGYVRVPapPFRLPDDPATPVILVGPGTGFAPLRGF 910 
ADB42227     1345 LQHREVQlrAlheASykqrtdddaiiplpthiGHARLFFGCRN-LNDYLYQQELETWHEAGVLtHLDV-AFSRL--DDEK 1420
WP_012172043 1033 IQERHAL--R---AQgr-------------atGPVLLFFGCRd-DGDYLYREELEAYRDEGTL-SLLAvGFSRRp-GTPR 1091
WP_015747835  964 LQERAAE--R---AIgr-------------pvGPTLLFRGCRHpDLDRIYGRELDTWAGQGWL-DLYE-AYSRPd-GGSG 1022
WP_013677914  943 LQERAGL--R---RRgv-------------pvGESLLFFGCRTpEQDFLYSDELRAFERDGIV-RLCM-AFSRV--ADNR 1000
WP_013952645  963 LEERAAQ--Q---AAgq-------------pvAPVQLYYGCRHpAHDWLYRDDVARWQAQGVV-QVHL-ACSVV--DGEP 1020
WP_015249791  946 LQERKAL--K---DRgh-------------dvGPSLLFFGCRNpSHDFLYEKELRDFEAKGLT-HLIP-AFSRVs-GQPK 1004
WP_050981161  936 MQERSLE--K---TP-----------------EKAVFFYGCRAkEVDQLYAEEFAQWEKEGWL-DLRP-VYSKApeKEGQ 991 
WP_015432709  389 LQALQRE--Q---RA-----------------SSHYLFFGERHrLHDFLYQNELEQYLHNGTLtKLFT-AFSRD--QAEK 443 
WP_015674137  390 LQNLAAQ--T---SA-----------------RQTYLFFGERYaAKDFLYQTELENYLKAGTLtQLFT-AFSRD--QAEK 444 
WP_080040673  911 LEERALR--G---AS-----------------GRAEVFTGCRHpEHDLLYAGELASWEAADGV-RVHR-AYSAVp-GHPY 965 
ADB42227     1421 IYVQDLIGQRSKDLWDVLSQpDCHYYICGDGQ-MADAVFEVLMTIAKTAGGLS-HAEAVNFFRHMQAE-NRFVMDVW 1494
WP_012172043 1092 TYVQDLLRTHGDAVREQVAA-GASILICGNARtMAPDVHAAFLELLGAGA-----------VAELEAG-GRYLQDVW 1155
WP_015747835 1023 RYVQQAVRDHGADVLDLLDR-DAVVYVCGNRHtMAPEVSSTIAALHADRTG----EAGEPWISELAAA-GRYVEDNW 1093
WP_013677914 1001 RYVQQAILDEQEDVRRLLDQ-GAHVYVCGNANtMAPAVRAALIEVHQGGDGTA-DTDGDAWLAGLRAA-QRYLEDIW 1074
WP_013952645 1021 RYVQDLLWQRRADVWARLNQ-GAIVYVCGDGRhMAPAVRQVLIQIGAEQGGMT-PEAASDWLAELVST-GRYRQDVF 1094
WP_015249791 1005 CYVQHSILQNAESVWDLLDH-GAVVYVCGDAArLAPDVRAAFHNISAAKTGHD-GRVADSWLYELQSN-NRYLEDVW 1078
WP_050981161  992 TYVQHRLWADRDAFWAAWEA-GAKIYICGDGEgMAPAVRQCLMDIYQEKAQAT-EAQALDWLMQIAGKdKRYFTDIF 1066
WP_015432709  444 VYIQDLLKQQAELIWQLIQQ-GAYFYVCGSKK-MSKAIDESLLEIAERIGHQPyIDDFNNIVAHLVAE-GRLLRDIY 517 
WP_015674137  445 FYVQDALAQQAALIWQLIEQ-GAYFYVCGSKT-MSKAIDETLLNVAAQVGNQPnIDAFNNIVAQLVAD-KRLFRDVY 518 
WP_080040673  966 RFVQDAVAAHADEVWELLEQ-GAHVYVCGDGLrMAPAVRQALLDMHRDRTGG--EEDGAAWLAGLEAA-GRYQQDVF 1038
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