Conserved Protein Domain Family
Vps53_N

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pfam04100: Vps53_N 
Vps53-like, N-terminal
Vps53 complexes with Vps52 and Vps54 to form a multi- subunit complex involved in regulating membrane trafficking events.
Statistics
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PSSM-Id: 427710
Aligned: 6 rows
Threshold Bit Score: 476.94
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5VIR6  40 ADFNAVEYINTLFPTEQSLANIDEVV-------NKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIK 112 human
Q9VQY8  43 PDFNTVDYINQLFPNEQSLAGIDETI-------QKMQCEVSLIDDNIRSVVRGQTNTGQDGQLALCEAQKVISSLFSHII 115 fruit fly
P34561  30 PNMSLMAQINELFPTEQSLTQLDSII-------ASVEGEIGELDNELAYLVETNANVSERGEEALKHAQDAMIELEKSIG 102 Caenorhabditis elegans
Q0WQF4   2 DKSSALEYINQMFPTEASLTGVEPLM-------QKIQGEIRRVDASILSAVRQQSNSGTKAKEDLADATRAVEELSHKIQ 74  thale cress
P87129  17 NEFKFVETLHELLPEDITYDDLGSLRls---lsERLQESVKKLDANKKTYEDAKLSMGEK----MDDLNSSIVSLLQELS 89  Schizosaccharomyces p...
P47061   6 VDYDPLEDITNILFSKESLNNIDELIsitrsykKQLQEDILKEENELKEHPKNSA-----------EIEASLRKVFQDFK 74  Saccharomyces cerevis...
Q5VIR6 113 DIKDKAEKSEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQGVMNVL-EHFHKY 191 human
Q9VQY8 116 DVKTRAERTEEMVKEITRDIKQLDCAKRNLTAAITTLNHLHMLVGGIESLNKLIERRSYGEILNPLQAITEVN-QHFQQF 194 fruit fly
P34561 103 SIRERTKSSDEIVREMTRDIKQLDIAKRNLTASITTLHHLHILLTGVESLGAWVDKKDYSSIARQLPAILNVL-QLFDAY 181 Caenorhabditis elegans
Q0WQF4  75 EIKSKAEQSEAMVQEICRDIKKLDFAKKNITTTITALHRLTMLVSAVEQLQVMASKRQYKEAAAQLEAVNQLC-NHFEAY 153 thale cress
P87129  90 TLQSVAENTQSSIVQMTSEIKNLDFAKQNLATSMTMLKRLQMLVTAYEKLRTLRQNQKFGEAISLMQATLQLL-NFFKKY 168 Schizosaccharomyces p...
P47061  75 ETQDVSASTELTISNLTEGISYLDIAKKNLTHSLTLFQNLKILTDSYIQCNELLSQGSFKKMVSPYKIMCSLAeNTFISY 154 Saccharomyces cerevis...
Q5VIR6 192 MGIPQIRQLSERVKAAQTELGQQILADFEEAF----PSQGTKRPGgpSNVLRDACLVANILDPRIKQEIIKKFIKQHLSE 267 human
Q9VQY8 195 SDIEEIKNLSQSVDKIQVTLAQQITEDFKEAFsakpSSQNQHRLG--LNQLADACKVMSVLDPKVKKELLKWFIAQQLEE 272 fruit fly
P34561 182 KESDQIANLSGQLDKLKASLTIQLAKDLKNAF----------QTGqlSDRITDMCRVAAALEGNVKENFVKWFIEQQLSE 251 Caenorhabditis elegans
Q0WQF4 154 RDVPKITELREKLNNIKQILKSHVFSDFSSL-----GTGKETEETnlLQKLSDSCLVVDALEPSVREELVNNFCSRELTS 228 thale cress
P87129 169 RSVERIASLSRSISEFQKSFYEQVFDTFQSQFkkesGMRGGFSPSs-VQYLNELCRFIDIFAGDPPESVIRWYCRHQLED 247 Schizosaccharomyces p...
P47061 155 KSLDEINYLLSSISRLKGDTLSKIKQNYNALFs--gGNISEHDTAltMELREGACELLDC-DTSTRAQMIDWCLDKLLFE 231 Saccharomyces cerevis...
Q5VIR6 268 YLVLFQENQDVAWLDKIDRRYAWIKRQLVDYEEK-YGRMFPREWCMAERIAVEFCHVTRAELAKIMRT--RAKEIEVKLL 344 human
Q9VQY8 273 YTHLFHENQDIAWLDKIDKRYAWLKRHLLDFEDK-YGPVFPLDWEVSERITVEFCRQTREQLAQIMAK--RTNEIDVRLL 349 fruit fly
P34561 252 YVIIYADNEEGAWLDKVDDRYKWFVRKLTDFERAgLSNIFPADWHMGRRLTSEFCTVTRDILYRIMTR--RRQDLDWKLL 329 Caenorhabditis elegans
Q0WQF4 229 YEQIF-EGAELAKLDKTERRYAWIKRRIRTNEEI--WKIFPASWHVPYRLCIQFCKQTRKQVESILVN--MKEKPVVAIL 303 thale cress
P87129 248 FMKVFRENEEAGSLENLPRRYTWFKKLLQTYDQL-HKPIFPPHWKVDFRLYEVFCEETKNDLSKLL----KDDRLSLQVF 322 Schizosaccharomyces p...
P47061 232 MKEIFRVDDEAGSLENLSRRYIYFKKILNNFNSK-FADYFLKDWEMAVRLTTTFYHITHKDLQTLLKRefKDKNPSIDLF 310 Saccharomyces cerevis...
Q5VIR6 345 LFAIQRTTNFEGFLAKRFsgctltdgtlkkl---espppstnpfleDEPTPEMEELAtekgdldqp---------kkpka 412 human
Q9VQY8 350 LFAINKTQAFEQLLSKRFtgv----------------------tlgAQPTDKARVLAeptttdg--------------av 393 fruit fly
P34561 330 GHAIQHTKMFEALLTKRF--------------------------------PEKDGIS----------------------- 354 Caenorhabditis elegans
Q0WQF4 304 LLALQSTVEFEKELEKKFgggvptkdieddieeigtwednsqniskIRKKYEKKFAAsqeteengfqqektgnkdlsvtg 383 thale cress
P87129 323 VASLEQTLEFESFIDHRFynt----------------------ksrFNSNFEPKERQ----------------------- 357 Schizosaccharomyces p...
P47061 311 MTALQSTLDFEKYIDVRF----------------------------SKKIKEPK-------------------------- 336 Saccharomyces cerevis...
Q5VIR6 413 pdnpFHGIVSKCFEPHLYVYIESQDKNLGELIDRFVADFK 452 human
Q9VQY8 394 gltvFHDQIGQCFKPHLDIYIRSIDRNLSELMDKFVEMSR 433 fruit fly
P34561 355 ----FEKAIWSVFDTFLDVFINAQEKTLNEFLDTCASKIR 390 Caenorhabditis elegans
Q0WQF4 384 agfnFRGMISSCFEPHLTPYIELEEKTLMDDLEKIVQEES 423 thale cress
P87129 358 ----AYNALSSVFEPHYTLYFNQQSQEFSILFENFALEKQ 393 Schizosaccharomyces pombe 972h-
P47061 337 --------LSSCFEPYLTLWVSHQNQMMEKKFLSYMSEPK 368 Saccharomyces cerevisiae S288C
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