Conserved Protein Domain Family
INCA1

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pfam15142: INCA1 
INCA1
This family of proteins inhibits cyclin-dependent kinase activity.
Statistics
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PSSM-Id: 464527
Aligned: 12 rows
Threshold Bit Score: 284.016
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q0VD86        12 PFAKCSRVVSRSPPPRLPSQSLRPMPQRYGDVFWKNLNQRPTPTWLEEQHIPPMLRATGCSQLGLY-PPEQLPPPEMLWR 90  human
XP_023100328  25 PFAKCSRVVSRPAPPRLPSQSLTLMPQRYGDLFWESLSQRPSPTWTEEWHIPPSPRATGCSQPGLY-PLERLPPPEVLCR 103
XP_004760503  26 PFAKCSRVVCRSAPPGLPAQSPGLMPQRYGDLFWENLSQKPSPTWMEEQYTPPLQRATGCSQPSLY-PPEGLPPPELLCR 104
XP_022274158   3 LFKGCSRVISRSTSPSLPPQHLGLMPQRYRDIFWENLSQRSSPTWTEEQYAPPLLRVPACSQPGLN-PPEGLPPPEVLCR 81 
DAA18912      12 PFAKCSRVVSRSPPHCLPSQSLGLMPQHYGDTFWENLSQRPSPTWMEEQYTPPLLRATGCSQPGQY-GPEGLPPPEVLCR 90 
XP_013836715 144 PFAKCSRVVSRSPPPSLPSQSLRLTPRHYGNTFWENLSQKPRPTWMEEPYTPPLLRVTGCSQLGLY-PPEGLPPPEMLCR 222
EHB13550       1 PHLRCSRVVLRSPPASLPSQGLRLTPNRYGDIFWENLTQRPSRVWMEEQYIPSMLRATGCSQLGSCpPPEGLPPPEMLCR 80 
XP_003416772  12 PFAKRSRVVSRSPPPSLPSQNLRMTPQRYGDIFWEKLSQRTSPIWMEEQYIPPMLRATGRSQAGLC-APGGLPPPEMLCR 90 
XP_005597762  25 PFAKCSRVVSRSPPPSLPSQSLRLTPQRYGDIFWENLSQRPSPTWMEEHYIPPLLRATGCSQPGLY-PPEGLPPPEMLCR 103
XP_003791272  12 PFAKCSRVVSRSLSPALPSQSPRPMAQRYGAVFWENLSQRPCPTWKEEKSIPSILRATGFSLPGLH-YPKGLPPPEMLCR 90 
XP_005337402  12 PFAKCSRVVSRSPPPSLPSQSLTSTSQRYGNVFWENLCQRPSPTWTEEQYIPPMLRNSGYSQPGLY-PLEGLPPPEMLCR 90 
EDM05047      30 PLPRCSRVVSRSSPCSLPSQKSRPMPQPYGEIFWENLSRRSNSNWMIEQYIPPILRATGCSQPGLH-PLEGLPPPEKLWR 108
Q0VD86        91 RKKRRPCLEGMqQQGLGGVPARVRAVTYHLEDLRRRQSIINELKKAQWGSSGAASEPVVLGEEGCGFPSTNEYPDLEEER 170 human
XP_023100328 104 RKRRRPHLAGM-QQGPAGIPAQVRAVTYHLEDLRRRQRIINELKKPQWDVSGAAPEPLAPATAGCGVPSATEYPGLEEAR 182
XP_004760503 105 RKRRRPPLAGM-QQGPGGIPARVRAVAYHLEDLRRRQRLINERKNAQWGTSGAASEPLALAHDLGGVPSATQYRGLEEER 183
XP_022274158  82 RKRRRPQVAGM-QQGPGCIPARVRAVAYHLEDLRRRQRLINEEKKAQWGGSGAACEPLALAEGSNRVPGTSKYQDLEEER 160
DAA18912      91 RKRRRPCSGGM-QQGSGGISARVRAVTHHLEDLRRRQRIINELKKAQWGSSGAASGPLLVDSDGCGFPSTTEHPDREEER 169
XP_013836715 223 RKRRRQHLAGM-QQGSGSIPARVRAVTYHLEDLRRRQRIINELKKAQWGSSGAAPEPLGLDEDGCGQPSTRRHPDPEEER 301
EHB13550      81 R-RRRPRLDRM-QQGPGGIPARVRAVAYHLEDLRRRQRTINEIKKAQWGISEAAPEPLVVPEGGCGFLSTSQYPDLEKEK 158
XP_003416772  91 RKRRKPRLAGV-QQGPVGIPARVRAVTYHLEDLRRRQRIIDELKKAQWGSSGATSEPLVLGGEGPRFSHTTGYPDLEEEQ 169
XP_005597762 104 RKRRRPHLVGT-QQGPGGIPARVRAVTYHLEDLRRRQRIINELKKAQWGSPEATSEPLVPDEEGCEFPSTTKYPALEAER 182
XP_003791272  91 RKKKRPHSEGM-QQGPGSIPARVRAVTYHLEDLRRRQRTIDELKKAQWGGSGAAFEPLMLAEEGCGFSSTTEYPDLEGER 169
XP_005337402  91 RKRRRSHLEGM-KQGPGSIPARVRAVSYHLEDLRKRQRTMDELKKAQWGNSRAASEPLVLDEEGCGFPSTTEYPDLEEEK 169
EDM05047     109 RKGKKLHLERM-QKGLGSTPARVRAVTYHLEDLRRRQGIINELKKAQWGSSEATPE-LPVFEEGCELLSTTKYLDVEEER 186
Q0VD86       171 ATYPQEEDRFLTPGRAQLLW 190 human
XP_023100328 183 ATYPQEEGHPLTTGRTQLLW 202
XP_004760503 184 AAYPQEDGHLLTSGGTQLLW 203
XP_022274158 161 AAYPQEEGHPLTTGRPQPVW 180
DAA18912     170 ADYPQEEDHFLTSGRAQLLW 189
XP_013836715 302 ANSPREEDDLLSPGRAQLLW 321
EHB13550     159 ATYPQEEDHFIIPGRAQLLW 178
XP_003416772 170 PT-----DHFLTPGRAQLLW 184
XP_005597762 183 ATYPWEEDHFLTPGR--AQL 200
XP_003791272 170 ATHPQEEGHLLTPGRAQLLW 189
XP_005337402 170 ATYPQEENHFVTPGRDQLLW 189
EDM05047     187 ATYPQGENYFVTP-RDQLLW 205
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