Conserved Protein Domain Family
TAF1D

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pfam15333: TAF1D 
TATA box-binding protein-associated factor 1D
TAF1D is a family of eukaryotic proteins that are members of the SL1 complex The SL1 complex includes TBP and TAF1A, TAF1B and TAF1C, and plays a role in RNA polymerase I transcription. Alternatives names have included 'JOSD3, Josephin domain containing 3'.
Statistics
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PSSM-Id: 464653
Aligned: 12 rows
Threshold Bit Score: 263.599
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_015135961   84 SKHH---RKCSDAPSKQKRRSqPSRPQAEADAGVPD-SESSDSSLP------------PqspvrpfeasqekKsKLNLKA 147 
XP_002754728   27 SDSSlfkTQCVPYSPKQGQRN-PIRKCVRTPGNVQAsDSSSDSSFE------------P-------------I-PLTMKA 79  
XP_003781384   28 SGSSlftTQCVPYSPKQRQRS-SIRKFVPLPESVEArDSSSDSSIE------------P----------------VTLKA 78  
NP_001296108   25 SGSSlfkTQCVPYSPKRRQRN-SIRKFVHSPESVQArDSSSDSSFE------------P-------------R-PLTLKA 77  
2_pfamImport    1 SGRSlfkTQCVP-SPKWRQRN-PSRICVSSLESAQArDSSSDSSLE------------P-------------R-PLTLKA 52  
XP_003764368   17 SSSSlfkTQCDPISPKRRPRNlSTSIVIQSPAKTQLrDDSSESSSE------------L-------------E-PFNLRV 70  
XP_007666311   59 SGSSlfrTQSAAALPKRRLRSqSSRNSIKSVAEKPVaDSSSDSSSE------------M-------------RlPYVLRA 113 
ELV10659       24 SGSSlfkTQCVPSSPTRRQRN-QIQKCVYSPKNIKE-DSSSYSSFE------------P-------------K-PLTLKA 75  
XP_013006602   23 SGSSlfrTQCAPSLSQRTPRN-PMRKFAHIPESVQT-DSSSDSSIE------------P-------------R-PLTLKA 74  
Q5M948         28 SNSSlfkTQCVP-SPTRKQRI-PTVKCVPSLASVET-DSSSDSSLE------------P-------------R-PLTLKA 78   Norway rat
EGW11943       27 SSDSlfkTQYVL-SPTRKQRN-PTTKRVTLPANVDT-DTSSDSSIE------------P-------------R-LLTLKA 77  
XP_010704403   92 A-----------VPSKQKKKSqPSRQQPEADAGVPG-SESSDSSLPtqsparppeasqEk------------KsKLNLKA 147  turkey
XP_015135961  148 -IFAyHFRgrKFK-AAAHRKYRSSGSQKTKKPSehsRRRggkqpmTASPQER-RKRLKDRGFQFPFVEKHYGRKHiPLNM 224 
XP_002754728   80 -IFE-RFKnrKKKyKKKKKRYQPTGRPRGRPEG---RRN------PLCSLIDkKKEFRSRGPGFPFLESENEKKA-PWKK 147 
XP_003781384   79 -IFD-RYK--NRKhKRKKRKYKPTGRKRGRPKG---RKN------TRSSRTD-KKLF-NKGPGFPFVESENEGKPlPWRK 143 
NP_001296108   78 -IFE-RFK----KkKRKKRKYKPTGRPRGRPKG---RRS------TRCSQIT-KKHIRDRGPGFPFLESKNGRRPlPWRK 141 
2_pfamImport   53 tIFE-RFK----KkKCKKRKYEPTGRP-GRTKG---RKN------TK-PQIN-KKQFKDKTS-LPLLESDTGRKPlLWRK 114 
XP_003764368   71 -IFE-NWK----KkKRRKRKYKPTGRPRGRPKGsfkAKQ------SLRIRPK-KDLFRDKGFQFPLVESENGRKPlLWKK 137 
XP_007666311  114 -----DFKcrQKR-KYRKKKYKPTGNPRGRPKGtrgILN------IHTTQEQ-KRLFGDKGFQFPLIQRELRKKQlPWKM 180 
ELV10659       76 -IFE-RFK----KrNRKKRKYKPT----GRPKG---SKN------TRRSQID-KKQVRGKGHKF--TESENRRNLlPWRK 133 
XP_013006602   75 -IFE-RFK---KKkKRKKRKYKPKLTPRGRPKG---RRN------IRKSQID-KKQIKDKGPRFPILQSEDGRKPlPWRK 139 
Q5M948         79 -IFE-RFKk-KKRkKRKKRKYKPKLRRQGRPSG---TRN------IRRSQID-AKQIKDKGAVFPFLESESGRKTlPWKK 145  Norway rat
EGW11943       78 -IFE-RFK----KkKRKKRKYKPKLRPRGRPPGiknARN------PRRSQIG-VKQIKNKGAVFPFLESENGRKPlPWKK 144 
XP_010704403  148 -IFAyHFRgrKFK-AAAHRKYRSSGSQKKKGASgcsQRRsgkqpmTASPQER-RKRLKDRGFQFPFVEKHYGRKHiPLKM 224  turkey
XP_015135961  225 VLSYEQAAAKGYFQYVEMLKYEEHLKKALKALEASEDLERECLAVRKHKYLDDE-GPISPIQETNDDddgDNNCLGSDNp 303 
XP_002754728  148 ILTFEQAVARGFFNYIEKLKYEHHLKESLKQMNVGEDLENEDFDSRRYKYLDDE-GSISPIEESTAE---DEDTTHLED- 222 
XP_003781384  144 ILTYEQAVARGFFNYIEKLKYEHYLKESLNQMDAGEDLEKEDFDSRRYKYLDDD-GSISPIEESVAE---DEDAAH---- 215 
NP_001296108  142 ILTFEQAVARGFFNYLEKLKYEYHLKESLKQMNVGEDLEKDDLDSRRYKYLDDD-GSLSPIEELAAE---DEVAANLEHd 217 
2_pfamImport  115 SLTFEPTVARGFFNYLEKLKYEYHLKGSSKQMNAGEDLEEKDPDSHRYKHLDDS-ESISPTEES-AE---DEVATNLESg 189 
XP_003764368  138 ILGYEQAVARGFFNYIKEKKCESHLGEALKQLDVGEDLEK-DFAVRKYKYLDDD-GSISPIEEPNVE---DS---ELNEp 209 
XP_007666311  181 ILTYEQAVARGFFNYIERLKFEKSLKEALSQLDTGEDVDNEELHMRGYRYVDDE-GAISPIEELNAE---DG--GDSDDp 254 
ELV10659      134 ILTFEQHVARRFFNYIEKLKYEHHLKESLNKMNVGEDLEKEDLDSCRYKYLDDD-GSISPIEEPVT----DE-AMNLEPd 207 
XP_013006602  140 ILSFEQAVARGFFNYIEKLKYEHHLKESLKQMNVSEDLEKEDLDSRRYKYLDDD-GSISPIEESEGE---DE-RTHLEH- 213 
Q5M948        146 ILTYEQAVARGFFHHIEKLKYEHHLKECLSQMHAGEDLEKEDFDSRRHKYMDDD-GPLSPIEEPSTE---DE-ATDPQ-- 218  Norway rat
EGW11943      145 ILTYEQAVARGFFHHIEKLKYEHHLKECLKQMHAGEDLEKEDFESRRHKYIDDEgGPLSPIEEPLTE---DE-ATNPE-- 218 
XP_010704403  225 VLSYEQAAAKGYFQYVEMLKYEEHLKKALKALEASDDLERECLAVRKHKYLDDE-GPLSPIQETNDD---DNNCLGTDNp 300  turkey
XP_015135961  304 EDFDVRVVDNSsFIISSKIPNK 325 
XP_002754728  223 DECDIKLAGDS-FIVSSEFPVR 243 
XP_003781384  216 GECDITLGADSsFIISSDFPRK 237 
NP_001296108  218 DECDIKLVEDScFIISSELPKK 239 
2_pfamImport  190 DECDVKLVENNyFIVSSELPKN 211 
XP_003764368  210 VECDIKLVENScFIISTEFPKK 231 
XP_007666311  255 DRWDARIVENScFILSTKFPKK 276 
ELV10659      208 DECDIKLVEDScFIISSEFPVS 229 
XP_013006602  214 DECDIKLVEEScFIISSEFPNK 235 
Q5M948        219 SECDIKLVEDScFIISTEFPRK 240  Norway rat
EGW11943      219 SECDIKLVEDTcFIISSEFSKR 240 
XP_010704403  301 EDLDVRVVDNScFIISSKIPNK 322  turkey
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