Conserved Protein Domain Family
RecQ

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COG0514: RecQ 
Superfamily II DNA helicase RecQ [Replication, recombination and repair]
Statistics
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PSSM-Id: 440280
Aligned: 701 rows
Threshold Bit Score: 420.701
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_108719704  120 LRE-------EAEAALRALVGrvDAALREDQWRAVHALVAErR-RALVVQRTGWGKSAVYFVATALLrargAGPTVIVSP 191 
WP_083457800   54 RDD-------DLDRQLSERFG--LPSFRPWQREAVAEILHG-SgRCLVLAPTGGGKSLCYQFPASVL----GGTSIVISP 119 
WP_050726362    4 SHA-------EIAGALERHFG--FAGFRPGQEAVVRSVLAG-K-PTVAVMPTGAGKSLCYQLPALLL----PGTALIVSP 68  
AKV00715        1 -mD-------PLEEALRSRFG--LDSFRPWQREAIDAVLGSpG-RALVVAPTGGGKSLTYQFPAAVL----EGTTLVISP 65  
WP_013250560    1 -mD-------DLSTQLSQTFG--FTAFRAGQREVMEAVLTR-R-DAMAVMPTGQGKSLCYQLPATLL----PGVTLVISP 64  
APR75632      720 awtsrgervtdLRALLEKAFG--FSAFRPYQEAVCRAATEG-H-DLLLVMPTGAGKSLCYQLPGLAR----GGTTLVISP 791 
WP_012932311    3 AAT-------DPREALHRHFG--FDDFRPGQAAAVGAALDG-R-DALVVMPTGAGKSLCYQLPALVR----DDLTLVVSP 67  
AEJ38600       10 QWA-------RINGVLTRVFG--LTALRPGQADVIARVLQG-R-SVLAVMPTGAGKSLTYQLPSLLM----ARPVLVISP 74  
WP_082363546   18 TASrrlapalDLDALLQERFG--IPSFRPWQREAIDALLGEdR-RVLLVAPTGGGKSLCYQLPAVAL----DGTALVLSP 90  
AKU97724      668 RTN-------DLAGILRAEFG--FESFRPYQEDVCRAAASG-K-DVLLVMPTGAGKSLCYQLPGIAR----GGTTLVVSP 732 
WP_108719704  192 LLALMRDQVAAAARAGIR-AETINSA-NVTEWESVHAAIAAGDVDVLLCSPERLNNPGFRAeVLPRlaAEAGLVVVDEAH 269 
WP_083457800  120 LIALMEDQVRSLNDRGIP-ATYLASTvDADERRARERDLFAGKFALVYIAPERLAAPGVVE-KLAR--LRPPLVAIDEAH 195 
WP_050726362   69 LVALMKDQVDSLSARGIP-ATFINSSiDDAEKARRLDAVRRGAFKLVYVAPERFRSAAFVE-AIRE--IEISLYAVDEAH 144 
AKV00715       66 LVALMEDQVRSLTARGIE-ATYLASTlELDERNARESAMLRGAYKLVYAAPERLASESFVR-MLSR--CKIALVAIDEAH 141 
WP_013250560   65 LIALMQDQVTGLKARGIA-AAAFHSGlSEQERDRVVLDLKLRRVQLLYLAPERMQHERFLR-LLRS--LWVSLLVVDEAH 140 
APR75632      792 LIALMEDQTEKLRSFGLA-ADRIHSGrDRASSRQAATDYLKGRLDYLFIAPERLRVPGFPE-MLAR--RKPSLVAVDEAH 867 
WP_012932311   68 LVSLMQDQVESLARIAPGsVALLNSQqSAAENRVALARAVSGDLRLLYVAPERFASPGFVA-QIER--ARIGLFVVDEAH 144 
AEJ38600       75 LVALMQEQVASLRTLGIL-AEALTGPlSEETWSTMSEKWRTGQTRLWFVAPERLFQARVFR-LLRA--YPPSFMAVDEAH 150 
WP_082363546   91 LISLMEDQVRALESRGVP-ATFFASTlPREEITRRFSALRRGAYKLVYAAPERLAFDGFLE-ALQA--SRLSLVAIDEAH 166 
AKU97724      733 LIALMEDQVAQLVGRGFA-AERIHSGrDRLSSRAACKAYLEGELDFLFIAPERLRVPGFPE-MLAR--RKPTLIAIDEAH 808 
WP_108719704  270 CVSDWGHDFRPDYRRIRTLLADLpAGTPVLATTATANARVSADVAEQLGVSadtaggsgvgtgagtgtgagtgasggngp 349 
WP_083457800  196 CISQWGHDFRPDYLRIGEVLRAL-APPRVVACTATATPAVRAEILEKLGLP----------------------------- 245 
WP_050726362  145 CISQWGHDFRPDYTRLGQVRWVL-RPPRTLALTATATPEVRDDIVRVLRLK----------------------------- 194 
AKV00715      142 CIAQWGHDFRPDYLRIGSLLERL-SPPRVLACTATATPEVRREIIEQLGFA----------------------------- 191 
WP_013250560  141 CISQWGHDFRPDYLNIGRLRREL-ENPPCLALTATATARVQADLCDRLSLQ----------------------------- 190 
APR75632      868 CISAWGHDFRPDYRMLGQHLPAL-RPAPVVALTATATPLVQDDILAQLDLP----------------------------- 917 
WP_012932311  145 CVSQWGHDFRPDYFRLADAARYL-RARAIMALTATATPRVADDIAARLGLA----------------------------- 194 
AEJ38600      151 CISQWGYDFRPEYRQIGKFRHQI-GNPPVLALTATAPPVVQREIEWHLRDKg---------------------------- 201 
WP_082363546  167 CIVQWGHDFRPEYLRIGDALRRL-APSRVLACTATATREARDEIIRRLGWSvpg-------------------------- 219 
AKU97724      809 CISQWGHDFRPDYRMLGERLPLL-RPAPVIALTATATPSVQDDIAEELGLS----------------------------- 858 
WP_108719704  350 daatapheD--------------------VL--VLRGSLDRESLRLAVLPRAdsAVRVTWLEGYLRQAaa---aGSG--- 401 
WP_083457800  246 --------Dg------------------eTK--VVLRGFARPNLHLSAIECDgrSSRRSWMMRAIDDA------LGSpre 291 
WP_050726362  195 --------D--------------------PK--VSVAGFDRPNLFFEVAKV---ANEHEKLGRiVRSC------RDG--- 232 
AKV00715      192 --------N--------------------TTfsEVLRGFARPNLHLAAKTVDgpKQARAAVIEALETA------IGQpri 237 
WP_013250560  191 --------D--------------------PL--RLVTGFRRPNLALSVRLCRsrQEKLAILDRAVREY------ETG--- 231 
APR75632      918 --------N--------------------AS--RFIHGFRRTNLGIEVVEVTp-sARADATRTLLAEP------GRR--- 957 
WP_012932311  195 --------E--------------------PV--RVTTGFDRPNLSFAVVPCRskQDKHRRIAAVLHDL------ESR--- 235 
AEJ38600      202 --------E--------------------PFd-ILTQPVDRPNIALDVQEVGtgAEKLHRVERLLAE-------EPG--- 242 
WP_082363546  220 ------aeDapsdlagpssqaspatardaPR--IILRGFARPNLHLEVRGVDgpRDAARWTARTLTSAlgrprtPKG--- 288 
AKU97724      859 --------S--------------------SA--RFIHGFRRTNIGVEVISRPp-gDRPDVVRRLLDDP------ARR--- 898 
WP_108719704  402 ---SGIVYCLTVAAAEEVASRLRAA-GHEVAAYTGRTDPAEREQLEADLLANRVTALVATSALGMGFDKPDLGFVVHLGA 477 
WP_083457800  292 pkgAAIVYAGTRRSTEEVAGLVAAR-GYRVAAYHAGLEPEQRSVVSEAFAKRQLDVVVATNAFGMGIDRPDIRCVVHVAP 370 
WP_050726362  233 ---GGVVYCATRRDVEKVAGMLDGR-GIRSFAYHAGMGDDDRRRIQDAFMAQDDAVVCATNAFGMGVDKPTIRFVAHFAI 308 
AKV00715      238 prgGAIVYAATRKTTEQYAELLRKR-GYNAAFYHAGLDGEARTRVADRFASRKFDVVVATNAFGMGIDRSDIRTVVHVQP 316 
WP_013250560  232 ---TILVYCATRRAVEEVAACLGAS-QSSVGYYHAGLSDEERRKVHDEFRVGAVRILAATNAFGMGIDKSDVRLVVHFDI 307 
APR75632      958 ---PAIVYASTRKVAEDVAKELGR--SFRVGAYHAGMDTGERDRVQTRFLGGDLDVIVATVAFGMGVDKSDVRTVVHVAL 1032
WP_012932311  236 ---PAIVYAGTRNGCEELARSLGRTlELDVAVYHAGLPRDRRAAVQRAFMAGDTPIVVATNAFGMGVDKADVRTVCHETV 312 
AEJ38600      243 ---AAILYASTRRATEWWADRLSERlTVPVVAYHAGLPRETRAAAEQAFRRRQVNRVVATSAFGMGIDRGDIRLIVHVDL 319 
WP_082363546  289 ---AGIVYAATRKGTEKLATALRAD-GWNAEAYHAGLPPEVRARISTAFADRELHLVVATNAFGMGIDRADVRVVVHAQP 364 
AKU97724      899 ---PAIVYAPTRNESEELASALSR--KVRAAAYHAGLATDVRDDVQARFLAGKLDVIVATTAFGMGIDKPDVRTVIHTAL 973 
WP_108719704  478 PGSPIAYYQQIGRAGRGVARADVVLAPGPEDAAIWAYFGSLAFPaeetvrtvldalehapdrtastarletevdlrrsrl 557 
WP_083457800  371 PGSIEAYYQEVGRAGRDGQPAWGLLLSGSNDIGLRRRLIEHGRDgqq--------------------------------- 417 
WP_050726362  309 PKAIEAYYQEAGRAGRDGRPARAVLLFNHADVYLQERLVEANHPsaamvrdvwkhlrtmgdgelpigerqvaaavsaspl 388 
AKV00715      317 PSSIEAYYQEVGRAGRDGDEAQGLLLCSGADIALRRRLVQMGSDgea--------------------------------- 363 
WP_013250560  308 PGSLEAYYQEVGRAGRDGRPAACLLLFHERDVATQEYFIQQASKesg--------------------------------- 354 
APR75632     1033 PGSIENYYQEIGRAGRDGKPSRVILMHSFVDRKTHEFFHERDYPdpsvldriykalrkapepkedlaarlrmepdvf--- 1109
WP_012932311  313 PQSVEAYYQEAGRAGRDGRPARCLLFSESRDKGLHVFFIERTQVedaafgavarrihrqagdngryeldlgvladvagcd 392 
AEJ38600      320 PESLDAYYQAVGRAGRDGEAARAVLVYRSADLVHRRHLADRGLVdrasletllqaiqkrsvvtvpedpegtvplilamle 399 
WP_082363546  365 PSSIEAYYQEVGRAGRDGLPASGVLLFSPADIALRRRMCQLGPDgge--------------------------------- 411 
AKU97724      974 PSTVEGYYQEIGRAGRDGKPSRALLIHSYVDTKTHTFFLERDYPetsivaavkkkisakgisisdlstrskiapeif--- 1050
WP_108719704  558 -------------emmlsvldvdgavekvrggwratgrpwtydaeryaRVARAREDEQAAMLAYErlaGSDDCRLGFLRA 624 
WP_083457800  418 ---------------------------------------------vdpAERDRQWNLFRELLRYV---EAGSCRHDFILR 449 
WP_050726362  389 qvg------saikhleraghlqrsarglvvlepgleddelrvdfdgiaARRQRELQMVRRMSSYA---YHEGCRRSYLLH 459 
AKV00715      364 ---------------------------------------------adaSLAARAWQLFRDLLRYI---DARSCRHDFVLR 395 
WP_013250560  355 ----------------------------------------------ssARADRMKTLLQDLLEYV---SGPTCRQLAILD 385 
APR75632     1110 ---------------ekaleklwihggclvefdgsvhlgepgwdrsyiAQKRHKEGELAQIGRYT---QGHGCRMLHLVK 1171
WP_012932311  393 rdqaraivghlaraglvqpapsppdrtigrlvgswdrsallacresagEAQRVRWRQYRSIWAFV---EQRRCRRGALLR 469 
AEJ38600      400 -------------dlgwifwrpvsggwrvirrqwptedavsvvwgridALRAWRQEQARHMIHYV---QESNCRRDTLLA 463 
WP_082363546  412 ---------------------------------------------aspLDAARAWQLFRELLRYV---DAWTCRHDFILR 443 
AKU97724     1051 ----------------ekaleklwvhggvriqgdtvvpgesdwrkayeKQRAHKTEQLDRMQTYA---ETTSCRMLGLVR 1111
WP_108719704  625 QLDDPD----LT--PgwrCGRCDLCAGaw-----fA-PLp------Da-----------AAVEEVRVALARagveVVPRr 675 
WP_083457800  450 YFGDEQe--lLG--G---CGHCDVCER--------L-ERe-----gEgerki--geeeaLIVRKALAGVAR----AQRR- 501 
WP_050726362  460 YFGDEPv----P------CSGCDVCNG--------P-SE----------------------------------------- 479 
AKV00715      396 YFGDERe--tLG--G---CGHCDVCQE--------I-AQha----gDdgtst---egttLIVRKALSAVAR----ANKR- 447 
WP_013250560  386 YFSDEAer-aLG--P---CGLCDRCVVts-----qP-SAhv---vgDe----------aTCAKAVLAAVSW----CRGR- 435 
APR75632     1172 HFGDQEd--sGE--P---CGACDICapdacvarrfrepshteqaalekilgaltrednqatgklyrenfdeakldrrsfe 1244
WP_012932311  470 HFGDRArpltARgvP---C--CDVCRPeia---pgPaARaggssarDsvrqagssrgtvGLDETILELVAS----AEPP- 536 
AEJ38600      464 YYRSPRi--pDS--R---FSCCDRCRGg------------------D-----------------------------RQR- 488 
WP_082363546  444 YFGDEAe--sLG--G---CGHCDVCEAlvasttadP-EAle----rDn-----------DIVRRALAGVAR----VKGA- 495 
AKU97724     1112 HFGDQNd--sGK--P---CGICDVCAP-------------------Da-----------CTAQEFRTASH------GER- 1147
WP_108719704  676 qwpTGM-ATLGVpl--aGRiAVEERAEAG------SAVAR-LDGVGLSAAVRDAVGPgagdgpv---------------- 729 
WP_083457800  502 ---AGMlAVADMl---hGV-SDERQKKLGftelstFGILKgHSREWLISLLRRMVTAglveitasefpmpylsalgakvm 574 
WP_050726362  480 ------------------Ppveelapapasrrgrk--------------------------------------------- 496 
AKV00715      448 ---AGMqAVAEMl---hGV-DSERTRRFGftglttFGLLKeHSLPWTVALLRALLAAgwidltttehpvpvltrngvsvm 520 
WP_013250560  436 ---FGVsRIVDMl---rGS-RSKALLTYGaeecpgYGGYHaWSKTALTRLVKALIDAgylqvegleyptldltrkgqesl 508 
APR75632     1245 hllgglvraglveiedasfhkggeridfqraslteegrekgvealgyvpleeeaakpprkrkskdkgtrerkstsargag 1324
WP_012932311  537 ---VGRaRAVEIl---rGS-RSKAIDEHSydglpaYGTFAhlr------------------------------------- 572 
AEJ38600      489 ------------------Sfe----------------------------------------------------------- 491 
WP_082363546  496 ---AGMqLIGSMl---vGE-SNERLRRIGldklstFGVLPaRTHAEAMMVLRVLLANgwidltdseypvplitpagwrvm 568 
AKU97724     1148 ---AAAlKIIEAlrerdGrav----------------------------------------------------------- 1165
WP_108719704  730 -----------------------------------------padlrpaVRsllerlvaegtridgv-------------- 754 
WP_083457800  575 raqepvrvllppvettkapkgrggtrverdgsarttaavaglssktaaAFerlravrleiakeqhvpayvvchdrvlvei 654 
WP_050726362  497 ---------------------------------drptaandegpydgeVFaalkelrlslakaegvppyvvfhdralraf 543 
AKV00715      521 kgeveariv-------lpleprspapsssrgrgkttrelpplnpddqaVFerlrthraeiarqkkvpayvvamdrtliem 593 
WP_013250560  509 kgispllmse------qvedpaasaikskasergssmapihtasvdpqLFerlrqlrrelaeeegvapfvifhdktlrni 582 
APR75632     1325 raskgtsdeksaadkkkdaqrraffarmkgkgrarag------------------------------------------- 1361
WP_012932311  573 ---------------------------------------------geeVMqrvdmln----------------------- 584 
AEJ38600      492 -----------------------------------------------tVRerlaawrqavgrqqgvspyvvmpeslmnql 524 
WP_082363546  569 raevptrvrlplglsrrair----------------------------------prvaraerraevalvadarhplhpaq 614 
AKU97724     1166 ----------------------------------------------gqIHrdlfgdgsl--------------------- 1178
WP_108719704  755 --vlvdsttrpqlvdhlAKGAAHVLGVPVV 782 
WP_083457800  655 aerrpttidemaqvrgmGPARIAAYGERFL 684 
WP_050726362  544 aralpqteeaflsvagaGPTKWERYGPHIL 573 
AKV00715      594 amvrpqenhellavhgmGPGRVEQYGEGFL 623 
WP_013250560  583 agykpvtlaalleipgiGEVKVERYGRRVL 612 
APR75632          ------------------------------     
WP_012932311  585 ----------------------argalprL 592 
AEJ38600      525 vlrqprtpaqlaeipgmGPKRLRQWGDEVL 554 
WP_082363546  615 pepaprrrkrrtstndaPDDTLEAPdd-aL 643 
AKU97724     1179 ---------------------drraldhvL 1187
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