6WVD


Conserved Protein Domain Family
Jagunal
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pfam07086: Jagunal 
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Jagunal, ER re-organization during oogenesis
Jagunal is an endoplasmic-reticulum (ER)-membrane protein found in eukaryotes. It is involved in reorganizing the ER in cells that must increase exocytic membrane traffic during development, that is, in the oocyte during vitellogenesis. It facilitates vesicular traffic in the subcortex.
Links
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Statistics
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PSSM-Id: 462086
Aligned: 31 rows
Threshold Bit Score: 168.974
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6WVD_A       143 MASRAGPRAAGTDGSDFQHRERVAMHYQMSVTLKYEIKKLIYVHLVIWLLLVAKMSVGHLRLL-SHDQVAM---PYQWEY 218
XP_003728147   1 MSSKGGPRAAGTDGSDFQHREQVASQYKTSVQLKSKFRTCLYINILVVLIQVVMFAGAHFHI------IPSdfyPSPWQY 74 
AFI34517       1 MASRAGPRAAGTDGSDFQHRERVAMHYQMSVTLKYEIKKLIYVHLVIWLLLVAKMSVGHLRLl-SHDQVAM---PYQWEY 76 
EGW06202       1 MASRAGPRAAGTDGSDFQHRERVAMHYQMSVTLKSEIKKLIYVHLVIWLLLVAKMCVGHLRLl-SHDQVAM---PYQWEY 76 
XP_005995812   1 MASRLGPRAAGTDGSDFQHREKVASHYQMSVVLKSKIKKLTCAQIVVWLLIAARVLVSYLKLv-SSDLIAV---PFQWEY 76 
XP_005807878   1 MASRAGPRASGTDGSDFQHRERVASHYQMSVALKSEIRKLNIVHVLIWVLMAAQVTVSQLSLv-SHKVVAS---PYQWEY 76 
XP_003961803   1 MTSRVGPRSAGPNGS-VKHRERVAPNYQMSSSLKSEVRKLNLVHLLIWLLVAAQVTVSHLNLv-SHDTVSM---PYQWEY 75 
Q5XJX0         1 MASRAGPRAAGTDGGDFKHREKVASHYQMSASSKSEIKKLTVVHFLIWILVAAQVAVSHLNLv-SHDLVAM---PYQWEY 76  zebrafish
EDO32175       1 MASRGGPRASGTDGSDFSHRERVASHYRESVRQKAKMKFCILIHMFFGVCVVGWMGLAISRAVki--------aPDPWIL 72 
XP_002127629   1 MSSYSGKTVAGSDGSDHSFREKVASQYKTSASLKSTIKTLFLLSFLPMLVVLIHIMQEDLEIRfLNVDLPQ---VEVWQY 77 

6WVD_A       219 PYLLSILPSLLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQQLYRHGKAYR--FLFGFSAVSIMYLVLVL 296
XP_003728147  75 TWMLSGVVSLIGLNALAKNKKEMLSLHDLGLTIFGFGGIFFGFTSQYSSHQRYIASGETKR---IADIPLHYIW-VFVLA 150
AFI34517      77 PYLLSILPSLLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQQLYRHGKAYR--FLFGFSAVSVMYLVLVL 154
EGW06202      77 PYLLSIVPSLLGLLSFPRNNISYLVLSMISMGLFSIAPLIYGSMEMFPAAQQLYRHGKAYR--FLFGFSAVSVMYLVLIL 154
XP_005995812  77 PYLLSIIPCIFGFMCLPRNNISYLVLSMISTGLFSISPLIFGSMEMFPMAQQLYRHGKGNR--FIFGFSAVSVMYLILVI 154
XP_005807878  77 PYLLSIVPTVFSFLALPRNNISYLVVSMISAGLFCVAPLIYGGMEMFPVAQQLYRHGKAYR--FIFGFSAVSVMYLVIVI 154
XP_003961803  76 PYLLSLIPLLCSSLSLPKNNISYLVLSMISGGLFSVAPLIYGSMEMFPVAQQLYRHGKAYR--FIFGFSAVTVMYVVMVI 153
Q5XJX0        77 PYLLSLVPSFIGALAMPKNNISYLVISMISAGLFSVAPLIFGAMEMFPLAQQLYRHGKAYR--FIFGFSAVSVMYLLMVI 154 zebrafish
EDO32175      73 LWLISVFPAIAGLSGLPKNQTKMMHVYSIGTMVTGIAPLMYGATFGIMQVMENFKRGHAPGtdDWRVLPMKMAMVAFV-- 150
XP_002127629  78 VYMLAPFITFIGYSSLHKNKATQMSIYIYFSLATLVPALLY---------KAWLNFTNPSQt-TLFKMPLSVLNYIFVVL 147

6WVD_A       297 AVQVHAWQLY-YSKKLLDSWFTST 319
XP_003728147 151 SNAINYLATYvYSIRLKAAWNVRK 174
AFI34517     155 AVQVHAWQLY-YSKKLLDSWFTST 177
EGW06202     155 AVQVHAWQLY-YSKKLLDSWFTST 177
XP_005995812 155 AVQVHGWQVY-YSKKLLDSWFTST 177
XP_005807878 155 AVQVHAWQIY-YSKQLLDQWFTAT 177
XP_003961803 154 AVQVHAWQLY-YMKKLLDSWFNTT 176
Q5XJX0       155 AIQVHAWQIY-YSKKLLDAWFNST 177 zebrafish
EDO32175     151 -IQAHAVSIY-YSNKLISAWNTKG 172
XP_002127629 148 TILMHAYSLF-CASKLVKAWKQKG 170
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