Conserved Protein Domain Family
Arm_2

?
pfam04826: Arm_2 
Armadillo-like
This domain contains armadillo-like repeats. Proteins containing this domain interact with numerous other proteins, through these interactions they are involved in a wide variety of processes including carcinogenesis, control of cellular ageing and survival, regulation of circadian rhythm and lysosomal sorting of G protein-coupled receptors.
Statistics
?
PSSM-Id: 461447
Aligned: 8 rows
Threshold Bit Score: 263.119
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q8N2F6        93 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQSIKE-KALNALNNLSVNVEN 171 human
XP_002933149  74 LQPHHLANLLDILVTSSDSSLQEKVLITLCNSAAFSANHDIIRSLGGITIIAKSLSDSSEQIKV-NALNALNNLSMNVQN 152
Q6A058       535 LGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKE-KALMAMNNLSENYEN 613 house mouse
Q6PB60       312 LDSPEFEKLVNILKSTTDPLIHKIAQIAMGIHKVHPFAQEFINEVGVVTLIESLLSFSSPEVSIkKAVITLNSSGDDRYN 391 house mouse
Q5RDG2       307 LEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVSNPNVKEHP-RALSMVDDSSESSEG 385 Sumatran orangutan
Q3UZB0       356 LEPVDFDKLVALLKLTRDPFIHEIATMIMGISPAYPFTQDIVHDVGITVMIENFVNNPNAKKYP-RTLN-INANPDAPEE 433 house mouse
Q8BHS6       118 LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKE-KALIVLNNLSVNAEN 196 house mouse
CAG03393      89 LEPQHLKVLLSRLQSSGDPAESQRILLTLGNAAAFTVNQNLIRDYEGIGTIAAFLSDPAAEVRV-QTLNALNNLSMNVRN 167 spotted green p...
Q8N2F6       172 QIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDHQHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAM 251 human
XP_002933149 153 QELIKDYINQTCSAISLSSLNSEVQLAGLRLIINMSVTDNYHNMVADHLPCFLYLLAEGNNIIQIYTLKVLVNLSANPTM 232
Q6A058       614 QGRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDM 693 house mouse
Q6PB60       392 --KVEFHVKHMCKETVSFPLNSPGQQSGLKIIGQLTTESVHHYIVVSYFSELFHLLSQGNRKTRNLVLKVFLNMSENPKA 469 house mouse
Q5RDG2       386 PKSGESYIHQVCKGILSCPMNSPVQLAGLKLLGHLSVKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHAN 465 Sumatran orangutan
Q3UZB0       434 VKETEAHVNKVCRDILCCPLNCSVQVEELKLLVSLSVKFDYHHVVIYYVRYFISLLNKGSVKIKFQILRVLLCLSKNQAN 513 house mouse
Q8BHS6       197 QRRLKVYMNQVCDDTVTSRLNSSVQLAGLRLLTNMTVTNEYQHILANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAM 276 house mouse
CAG03393     168 QDQIKVCVPQVLELIEVSPVNSELQLAALRLLTNLSVTDQHQHLFKTSIRLLLSLLVVGNEEL----------------- 230 spotted green p...
Q8N2F6       252 TEGLLRAQVDSSFLSLYDSHVAKEILLRVLTLFQNIKNCLKIEghlavqptftEGSLFFLLH 313 human
XP_002933149 233 TQTLLTAKGSQSLTSLFDSRVDREILVRVLIFAANLSKHLGSG----------HGYDLHANY 284
Q6A058       694 LKKLLGTQVPSSFSSLYNSYVESEILINALTLFEIIFDNLRAEvfny--refnKGSLFYLCT 753 house mouse
Q6PB60       470 ARDMINMKALAALKLIFNQKEAKANLVSAVAIFINIKEHIRKGsivvv-dhlsYNTLTAIFR 530 house mouse
Q5RDG2       466 TRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQVKTKaklftkekftKSELISIFQ 527 Sumatran orangutan
Q3UZB0       514 TRELISAEVMSSLVALFHKNESKANILHIIEIFENINFQFKKRaklftkemftKSELISIFR 575 house mouse
Q8BHS6       277 TRELLRAQVPSSLGSLFNKKEYKEVILKLLIIFENINDNFKWEenepaqnhfsEGSLFFFLK 338 house mouse
CAG03393     231 -------QAPASVLLLFDAQTASPVLLRLLTFAGNLR-AWRPSaqvahllrqtQDCLFRVML 284 spotted green pufferfish
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap