Conserved Protein Domain Family
DUF4552

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pfam15089: DUF4552 
Domain of unknown function (DUF4552)
This family of proteins is functionally uncharacterized. This family of proteins is found in vertebrates. Proteins in this family are typically between 425 and 649 amino acids in length.
Statistics
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PSSM-Id: 464495
Aligned: 7 rows
Threshold Bit Score: 631.172
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_006226294 225 SSETGDFLTESQiSVMMGDECGILYERRQPDFAVVKTSVPQIGANSGEEFSHFLEDGIHPTQRHLPDHHDSFINHNMINL 304
XP_003405428 290 SPGNRNFLTERP-AVIMGEDCGSMNERRESDFVTEKQTVQPFRGENRKAVLNCIEDANQAIPSSLSENCNSFFSQNMINL 368
EHB08720     230 NPENEDFLATRP-GVTSGEDWRSMNE-RQSDFIIEKQVAQRTWGENGKEISTFLKDVNQPAHSILSENCDSFVGQNMINL 307
Q86WS4       229 SLGNRNLLTKSP-AVIMDEDCRSTDEIRQSDYITEKHSIQHIWGKNGKEVSNFLEDVNQSTPNLLSENCDSFVSQNMINV 307 human
XP_012662921 231 SPGNRTFLAKRP-AIILGEDCGNM-----VDFIAGHQSVQHLWEESGKEVSNFLDDLNQPTPSFLSEKCDSFVSQNMINL 304 small-eared galago
XP_030104725 253 ySETGDFLTKR--SMIMGEDCRSLYERRQPDFAMEKPLVQQIYANNGEEFSNFLEDVIHPTQRHLPDNHNSFVSHSMIDL 330 house mouse
XP_006086848 451 SPGNRNFLAGSP-AIVMGEDCGSMDERRHSDFITEKQSVQHIWGENKEEVSNFLEDVSQPTPSLLPENFDSFINENAINL 529 little brown bat
XP_006226294 305 LSRDQPGRRATFNQCGYDClSDAHVV-SSDESQSTNGFIPRNFTVPRAASPNRPFS-ASYIETCQSNRPCQKQYTNNERN 382
XP_003405428 369 LNLDQQRIKENTDKCGCDS-GDICAVtSSSKKYFTDRCLRSIFTVPELTYSNSTFNkTSNPEKCQPKNGYQKKYINNEGN 447
EHB08720     308 LSIDQQVIQKTFDKSSYDSlGNACLVtNSDENHSTGVCIGSIFTVSESTCSNSAFNkTSCPEKCQPVKHNQKEHNSNEIR 387
Q86WS4       308 LNIDEQRIKKTFNKCDYDSmGDTCVVtSSDKNHVTDRCIRNIFTVPELTFSNSTLNkTSYPEKCQPNKKYQREYNKNERN 387 human
XP_012662921 305 LSIDQQRIKKTFDECDYDSmGDVCV--------ATDKCSRDIFTAPEFTFSNSTFNsTSYPGKHQLNKNNQNEYNSNERN 376 small-eared galago
XP_030104725 331 LSKDQPGRRATFTKCGYDSlSDTHVV-SSDESHSSSGLINGEFTVPQATSPNFPFN-TSYTETCQPNRPCQ-EYNSNEIN 407 house mouse
XP_006086848 530 LSIDQQRITKPFENCGYDSmG----VtNSDKNHSSDRC---IFRNPGLNFSSSNFNkTSYSEKCQPKRNYQKEYNNNEGN 602 little brown bat
XP_006226294 383 ELRRSLEKDCYPVSCGRRGKIESNNQLKTLQRNSQESPVYTMAEIPLEELHHKQSCDFGQNEMPVE-RRTGPLKGRPVPA 461
XP_003405428 448 NFSTSFEKHCYPASSEKTGKYESNYQKKIPQKKIQKYPVNNMGNIPLEELHSEQSWDMGLGETLMEeRGACSLKSSRTST 527
EHB08720     388 DLST-FE-DCYPASYENRGKHENGFQEKTSQKNIQEDPVNSMCNSHLAELHPNQSWDIGLDEILME-GGTCSLKGRPTFT 464
Q86WS4       388 DLSTSFENDYYPSSSERKEKFENDYQEKTPQKSIQKYPANSMGNIPSEELHSKQSWDFGLDEILMEeGGIYSLKSKRIST 467 human
XP_012662921 377 DLSTSFEKHYYPTNSEEKeKLENEYQEKILKENIQNYPLNSMSNIPLEELNSKQSWDFGGGE-NLVeGGICSLKGMPTST 455 small-eared galago
XP_030104725 408 EFRRSFEKDCYSIGCGRKGKIESDKQLKELQRNARKHPVYTMADIPLEELHCKQSCDFDQNEIPMErRGMCPLKGQPMST 487 house mouse
XP_006086848 603 NPSTSFEKNCYPASAEKKGKFEKDYQKKKPQIEIQKYPVNNM-SIPLEKLNSKKSWDFGLSENLIEeGGTCSINGAPKST 681 little brown bat
XP_006226294 462 EKIY--LESSQSSQSTSYSPRPTDSTFSSSSELLSEDEDQNQQ---QIEHSNK---KATETTDHGGLEKVEGHLGDITVK 533
XP_003405428 528 KKIY--LDSSQSSQSTGYSPRQTDSSYSSSSEMPSEDEDQVLP---QSEDSNRrfiETKETTNNVYLNRMSKLSDDRIIK 602
EHB08720     465 KKIY--LDSSQGSQCTSYSPRPTESCFSSSSEMPSENEEQILKtqdQSEASNEistKTTGTNNNFYLESMAELSDNSIDN 542
Q86WS4       468 KKIS--LDSAQSSRSTSYSPRPTDSCFSSSSDLPSEDEDQISQ---QIEDSNRmtiKTKEKMNNFYVERMAKLSGDRIVK 542 human
XP_012662921 456 KKIR--LCSSQSSQSTSYSPRTTDSYFSSSSEMVSEEEDQVPQ---KMEDSNRifiETREATNNFDLERMEKLSKDRIVK 530 small-eared galago
XP_030104725 488 EKIY--LESSQSSQSASYSPRPTESTFSSSTDLISEDEDQIQQ---QTEDSNK---KATETTGNCCLEKMENHFDDITVK 559 house mouse
XP_006086848 682 KKNFnnNDSSQSSLSSSYSPRATDSCFSSSSEMPSDDEDQTLQ---KIEDSSRrsiKTEETTNNFYLERMAEFPRDRIVK 758 little brown bat
XP_006226294 534 DNAKVHRENHKSHQSSEKDNSDTFPESQCNSEHTPQNKSTANCVLRAGRCDVGVQTEEAPLVGSRADVAVQCTIIAPCSC 613
XP_003405428 603 NNASIHKQNEISPQFSKKNNSDQFSQSQHNSAYILQNKTNNNCILQAAKCDAWVQTESEHAIEEKLDAAIQCDIISKCKC 682
EHB08720     543 SNAKFHKQNEKFYQYS--DNTNQFLQSQCDSAHALKSKAS-NCILQVVKCDTGVQTDREPVMEEKLDAAIQCDILWKCAC 619
Q86WS4       543 NDDKIHKQNENFYQFSVKNNTDQFPQLQCNSAHILQNKTNDNCVLQAARCDAGIQTESESVMEEKLDVAIQCDLISKCTC 622 human
XP_012662921 531 NNAKMDKRAKNFPQFSMKKDRDQSSQSQCDSAHALQSKTNEH-ILQVASCDAGVQTESAPVVEEKLDAAVQCDIISKCAC 609 small-eared galago
XP_030104725 560 DDATAHKQNHKCLQSSEKNNADAFPESQCNSEHTVQNKSTDNCVLQAGRCDVGVQTEEAPLVGNTADVAVQCTIITRCSC 639 house mouse
XP_006086848 759 NNDKIHKQTESFHQVSMKSNTDQSAQSPYNSTHVLQNQTSNNCTVQFVRCDAWVQTESEPIMKERLDAAIQCDIISQCKC 838 little brown bat
XP_006226294 614 KSspsvdteEESSLSKAGSCTEDMMSDTTGGQETPTDN 651
XP_003405428 683 RS-------DVSSLSNAERCSGNIKAETTGGQEILKNS 713
EHB08720     620 GR-------DVSSLRSVEGYTESITVDTTGGQDILKNN 650
Q86WS4       623 RS-------DVS-LCNLERCSGNIKADTTGGQEIHKNN 652 human
XP_012662921 610 SS-------DVS-LCNKEMCSENIKADTTGGQEIPTNN 639 small-eared galago
XP_030104725 640 MSspvlireKESSHPEAGSCTEDRTADTTGGQETPTSN 677 house mouse
XP_006086848 839 RS-------NESSLCNVERCSENIKADTTGGQEILKNN 869 little brown bat
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