Conserved Protein Domain Family
SEA

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smart00200: SEA 
Domain found in sea urchin sperm protein, enterokinase, agrin
Proposed function of regulating or binding carbohydrate sidechains.
Statistics
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PSSM-Id: 214554
Aligned: 20 rows
Threshold Bit Score: 83.6148
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q21281       1495 AVESWNLPLYVIRDGHEKITYSPSLSNPLNDDHKDLVSRFESGVAQSYDKTplkgAFVTAEVNEIENPEsrkK---SWDT 1571 Caenorhabditi...
NP_001022675 2465 VVESWNVPLWVVRDKEKPIVFSESFDNPQTPVYKDYSKRLEKGIEGCYPHTelknAFVTAEVNDIVNPVlmnA---SYDT 2541 nematode
NP_001022675 2289 EVQETPFELRVVTRDQRPLMYSTEFGSQKSPSYVEIVELFEKNMARTFGGTslapRYVNTKVDYITHPKtknS---SWDQ 2365 nematode
NP_498645    1322 PTTSIPLVVRVMEYDGEPIQYRTDYSKPDTQAHIEIVDAVKKSVGKIIGKTdvapRFVTTDVNYITNPK---VqnsEWDK 1398 nematode
EDL81364     1023 ATKAFQGVLELEGVEGQELFYTPEMADPKSELFGETARSIESTLDDLFRNSdvkkDFWSVRLRELGPGK---L---VRAI 1096 Norway rat
P31696       1144 ATKVFQGVLILEEVEGQELFYTPEMADPKSELFGETARSIESALDELFRNSdvknDFKSIRVRDLGQSS---A---VRVI 1217 chicken
NP_999632      81 VAQQFAGSFSVTQVGGSNVLYSADLADTDSAAFASLAADVEDALDTVYQAStmadIYLGSEVWGVPEWL---Y---RGRL 154  purple urchin
EAW94997       35 QMVYFRALVNFTRS----IEYSPQLEDAGSREFREVSEAVVDTLESEYLKIpgdqVVSVVFIKELDGW----V---FVEL 103  human
AAC53572      128 PTVAASVGVSVTVTSQE---YSEKLQDRKSEEFSNFNKTFTKQMALIYAGIp---EYEGVIIKNLSKGS---I---VVDY 195  house mouse
NP_034869     274 KGTTFPGDISMSVSE------TANLEDENSVGYQELYNSVTDFFETTFNKT----DYGQTVIIKVSTAP---S---RSAR 337  house mouse
Q21281       1572 GILYNFTSH--Fv-KGSVAEPASVFTDLI-D--YIQKR-----ND---FEVGKSKLFISPEQ 1619 Caenorhabditis elegans
NP_001022675 2542 GLLFNTTVH--Fr-KGMVHVPSDAYYQLI-K--YVTKE-----NN---NEVGDSELYLNPTQ 2589 nematode
NP_001022675 2366 GLLFKYEVQ--TtkSQSQPIDECELWKQM-Q--ASLDR-----TN---GAIGGGSLRVASDT 2414 nematode
NP_498645    1399 GLLGNVSVH--L--AGKEEVDKCRFYEQF-A--EIVRE-----MG---GRVDRIKLSDDADL 1445 nematode
EDL81364     1097 VDVHFDPTT--AfqASDVGQALLRQIQVS-Rp-WALAV-----RRp-lQEHVRFLDFDWFPt 1148 Norway rat
P31696       1218 VESHFDPATsyT--AADVQAASLKQIRASkK--RTILV-----KKp-qQEHVKFMDFDwipr 1269 chicken
NP_999632     155 HVLFATE-D--A--GQPVLVNSTDATEAF-T--TALAA-----EA---ANLGitiddstitv 200  purple urchin
EAW94997      104 DVGSEGNAD-----GAQIQEMLLRVISSG-S--VASYV-----TS---PQGFQFRRLGTVPQ 149  human
AAC53572      196 DVILKAKYT--P--G--FENTLDTVVKNL-E----TKI-----KNateVQVQDVNNNCSAll 241  house mouse
NP_034869     338 SAMRDATKD--V--SVSVVNIFGADTKET-EksVSSAIetaikTS---GNVKDYVSINLCDH 391  house mouse
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