Conserved Protein Domain Family
cwf18

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pfam08315: cwf18 
cwf18 pre-mRNA splicing factor
The cwf18 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe.
Statistics
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PSSM-Id: 462423
Aligned: 129 rows
Threshold Bit Score: 80.7343
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ERT01815              6 ALSAAADDRKARLAKLRSIKRKQPgDEIVPPESDRaspavv--------tqpkshGDETGEEGNTgeireagema----v 73 
WGS:AATM:SJAG_01810   3 tFNEASESRKQRLAELRRINQLQ--REQQNHEGN---------------------DNENETNSSV--------------- 44 
Q9UU80                3 SLDEVAESRKQRLAELRKIKQLE--NKTRDS---------------------------QEVQKNV--------------- 38  Schizosa...
KJE89293             11 SLQDEAYKRRARLRAMREGAAASAvRRTNDDNDNNdndngdndddgkqtrhssqaTGGDRKRWRGednideadessamdd 90 
EFO23336             28 SLEEEANERKRRLKEMRERMTQQ--QEDDGTE--------------------------LSNKSVK--------------- 64 
PDM82853             22 aVEEAIAARKRRLMEMKSRMNGVemkeedydkee--------------------------------------------tt 57 
Q95XJ1               22 SLEAAAKARKRRLLAMKSKIHGIE-MQEEDYDEGE--------------------TSTKKSREVG--------------- 65  Caenorha...
EDV94635              9 KLTEESLKRKERLQKLREQAQSK--TGGVTE---------------------------NADKLPK--------------- 44 
Q7Q2C9               11 RLQEEALKRKNRLKELRHKRNHE--ELQQIMVN------------------------EVSANIPK--------------- 49  Anophele...
XP_001950344         13 lLEEEARKRKERLANLKKSLENK--NEPKNNED------------------------SVEKPLPK--------------- 51 
ERT01815             74 erdvsrlhLSGRNYDPETR-NARLGFEVEPNLAagdDTVEAQAAKLEADVRREQQEEeggdgegadgdarphdgGGKPID 152
WGS:AATM:SJAG_01810  45 --------LKFRNYDPVTQ-APKMGFVEPPTIGe--ETVEKVAANIEEETQKVLEEQqa--------------iPEEELD 99 
Q9UU80               39 --------IEHRNYDPEVQ-APKMGFVEPPNMI---ESVEALSKEIEEKTKRKIEEQss--------------vPVEELD 92  Schizosa...
KJE89293             91 gsndadttLRFRNYTPNDA-KLANAQIEHPDL----PEPEKDVAEIAKADAR-----------------------IHDID 142
EFO23336             65 --------LTFRSYEPQSDlGDKRDGVDL-------FAVEKEIADQLADTQDTRAV--------------------EQID 109
PDM82853             58 tkkskgqeKTFRSYQPVDA---SVGDVDPSVKTn-lRAVEEEIEEQLRLSKHKYYYYyrla---------ndtsHVDKID 124
Q95XJ1               66 --------REFRNHKPDDAvGTQNVDMDL-------DIVQREITEHLKDVLHEKAI--------------------DSVD 110 Caenorha...
EDV94635             45 --------PIFRSYKPQNE-NTVGEVLAQEPT----GDIESAVQSQLNLLHQPMVI--------------------DEID 91 
Q7Q2C9               50 --------PVFRNYKHVTEyEIQESSAIANQA----GIVEKQIDVQLEMMTTPIVI--------------------DEID 97  Anophele...
XP_001950344         52 --------PRFKSYIPEDE-GLKAELIPTPQP----GDIVAEVEDQLKAGETVFTV--------------------QELD 98 
ERT01815            153 LFKLQPKKPNWDLKRELNKRLEPLNARTDNAIGRLVRERL 192
WGS:AATM:SJAG_01810 100 LTSLRPKKATWDLERDLKERMTALETATQNAKAYYIRQ-T 138
Q9UU80               93 LVTLRPKKPTWDLERDLKERMRSLETQNQNAIAFYIQQ-L 131 Schizosaccharomyces pombe 972h-
KJE89293            143 LVNLAPRKQNWDLKRDVTKKLEKLERRTNRAIAELIRDRL 182
EFO23336            110 ITTLAPRKIDWDLKRDIAERLEKLERRTERAMAQLIRERL 149
PDM82853            125 LQALAPKKVDWDLKRDLASKLEKLERRTQAGIAHLIRERL 164
Q95XJ1              111 LAMLAPKKIDWDLKRDIESKLQKLERRTQKAVATIIRQRL 150 Caenorhabditis elegans
EDV94635             92 ITNLAPRKPDWDLKRDVSKKLERLERRTQKAIAELIRERL 131
Q7Q2C9               98 IVNLAPRKPDWDLKRDVSKKLEKLDRKTQKAIAEIIRDRL 137 Anopheles gambiae str. PEST
XP_001950344         99 LNTLAPRKPDWDLKRDIEKRMTKLERRTQRAIAELIRDRL 138
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