Conserved Protein Domain Family
2A1904

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TIGR00927: 2A1904 
K+-dependent Na+/Ca+ exchanger
[Transport and binding proteins, Cations and iron carrying compounds]
Statistics
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PSSM-Id: 273344
Aligned: 4 rows
Threshold Bit Score: 1608.9
Created: 7-Oct-2014
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAA47108    1 MGKLIRMGAQERRSLWPKRLHWSRPLFLLGMLIIGSTYQYLTSPQGLPTLWAAVSSQHPVKVASRDLSNKEMMMVSSETS 80   cattle
AAC18119    1 MGKLIRMGVQERRLLWPKRLHWRRLLFLLGMLIMGSTYQYLRSPRGLPSLCAAVSSQHPVKLARRDLSNNEMMMVSSDPP 80   bottlenosed dolphin
AAC16732    1 MGKLIRMGPQERWLLRTKRLHWSRLLFLLGMLIIGSTYQHLRRPRGLSSLWAAVSSHQPIKLASRDLSSEEMMMMSSSPS 80   human
AAD53121    1 MGKLIRMGTQERRLLRPKRLHWSRLLFFLGMLIIGSTYQHLRRPQNPPSMWTKVSSQQPIKLAIRDLPNDEITVTDKDPP 80   Norway rat
CAA47108   81 KSSSEMEVEAWAPEATAGRDGTPPGIARKNTPSTPRGTASITPAIPNN-YSPTPTGTGKVKEDTSATPSGVLNHY--TQS 157  cattle
AAC18119   81 KSSPEMEVETWAPQATVGRDGTTPGVTMENTPSIPRRIANVIPATPKSsDSPAAARTEKVKEDTPATPSGALNHYppTSG 160  bottlenosed dolphin
AAC16732   81 KPSSEMGGKMLVPQASVGSDEATLSMTVENIPSMPKRTAKMIPTTTKNnYSPTAAGTERRKEDTPTS-SRTLTYYtsTSS 159  human
AAD53121   81 EASSEVEGEMLAPQDTVIIGEAAPSIAMEDTPNPP-ITTKITPTSLKNnYSPTTAGTRRQKENIPPTPSRAPSHFisTSG 159  Norway rat
CAA47108  158 RPMVNSYTRLTaRGEVKSSRPTQSRGKEEKYSPSPLGRMVNSYAPSTLMTMPRSHGITPRTTVKDREIMATKKMLATNPS 237  cattle
AAC18119  161 RPVVNNYTPATrRGEVKSYRPTQARGKVRKYTPSPLGRMVNSYAPSTFMTMTRSHGITPRATVKDSEIMTTNKILETNPS 240  bottlenosed dolphin
AAC16732  160 RQIVKKYTPTP-RGEMKSYSPTQVREKV-KYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDITATYKILETNSL 237  human
AAD53121  160 RQRVKSYTPKP-RGGRKSSSPTHTREEGRMHTPSPAG-------------APR--TISPTSTEKDSETTATYRMLEPR-S 222  Norway rat
CAA47108  238 KRLVEKTTPTPLKGITDNTPTFLLSDLETDTLTSPRNVVEKKTLTTPRRVDSNSSTNHQGLVGKNNLTTPQGMVLEHTAA 317  cattle
AAC18119  241 KRVLGETTPTPLKGVTDNVLPFLINDLETDILTSPRNVAEGKTLTTTRRVDNNSSTNHRGLVGKNSLTTPQGTVLEHTAA 320  bottlenosed dolphin
AAC16732  238 KRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPRRVESNSSAHPWGLVGKSNPKTPQGTVLLHTPA 317  human
AAD53121  223 ERTAGKTS---LKRMVPNTRTFLTREVETDLVTSP-SLVGKNTLGSPRRGERNSST------------TPLRAVLQPTPA 286  Norway rat
CAA47108  318 VSEGQVTISTMTrssptETKASTDAWKVRNPLPRTSAPIIRISSATFRGLLKNPSKAPSTPAAPRVRANPTIQVRHCLVV 397  cattle
AAC18119  321 TSEGQVAVSITT-----ETKASTAAWKARNPSSRTSAPTVGISSATFWGLVKNPSPAPTTPATPRVRASPTTQVHHCVVV 395  bottlenosed dolphin
AAC16732  318 TSEGQVTISTMTgsspaETKAFTAAWSLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVV 397  human
AAD53121  287 TSEEQVTASIRMgstpaTTEGSTAAQRIGNPLSGTSTPAVRIASVTDR--EKRPSTAHGTLVTPQVKAVLTTQVHRCVVV 364  Norway rat
CAA47108  398 EPAPVAPTAPSPSWTTAVIPGIPSP------SGQPDLYPKAEYPRDLFSVEERRQGWVVLHIFGMMYVFVALAIVCDEYF 471  cattle
AAC18119  396 EPVPVSSTDPSPSLTTAGMPETPSPsv--lpSGQPDLHPKAEYPRDLFSVKERRQGWVVLHIFGMLYVFVALAIVCDEYF 473  bottlenosed dolphin
AAC16732  398 KPTPAMLTTPSPSLTTALLPEELSPspsvlpPSLPDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYF 477  human
AAD53121  365 KPAPAVPMTPSPSMTAILFPEAPTSgpsalpPGWPNLHPKAEYPPDLFSVEDRRQGWVVLHIFGMTYVFVALAIVCDEYF 444  Norway rat
CAA47108  472 VPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWP 551  cattle
AAC18119  474 VPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGIFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWP 553  bottlenosed dolphin
AAC16732  478 VPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWP 557  human
AAD53121  445 VPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILNLTWWP 524  Norway rat
CAA47108  552 LFRDITFYIFDLMMLILFFLDSLIAWWESVLLLLAYAFYVFTMKWNQQLELWVKEQLNKRPVAKVMALGDLSKpgdgtvv 631  cattle
AAC18119  554 LFRDITFYILDLMMLILFFLDSLIVWWESLLLLLAYALYVFTMKWNKQLELWVKKQLSRRPVPKVMALGDLSK------- 626  bottlenosed dolphin
AAC16732  558 LFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWVKEQLSRRPVAKVMALEDLSKpgdgaia 637  human
AAD53121  525 LFRDVSFYILDLSMLIVFFLDSLIAWWESLLLLLAYALYVFTMKWNKQIERWVKEQLSRRPVAKVMALGDLSKpsdgaie 604  Norway rat
CAA47108  632 vdeqqdnkklklssmltrgsssaslhnstirstiyqlmlhsldplgearpskdkeeetlipeakatpqakaeskpeeepa 711  cattle
AAC18119      --------------------------------------------------------------------------------      bottlenosed dolphin
AAC16732  638 vdelqdnkklklpslltrgssstslhn---------------------------------------------stirstiy 672  human
AAD53121  605 eneqqdnkklklpsvltrgsssaslhnsiirstiyhlmlhsldplgearpskdkqeslnqearvlpqtkaesssdeeepa 684  Norway rat
CAA47108  712 klpevtvtpapapdvkgdqeedpgsqGVGAEAENTGERTGGEAEAP-------AEGENGERSGGDAA-----LGGESEGK 779  cattle
AAC18119  627 --------------------------GDVAEAESTGERTDNEVKTP-------GEGENGEQSGGEAQ-----PEGEGEEK 668  bottlenosed dolphin
AAC16732  673 qlmlhsldplrevrlakekeeeslnqGARAQPQAKAESKPEEEEPAklpavtvTPAPVPDIKGDQKE-----NPGGQEDV 747  human
AAD53121  685 elpavtvtpapapedkgdqeedpgcqEDVDEAEHRGDMTGEEGEREt-----eAEGKKDEEGETEAErkedgQEEETETK 759  Norway rat
CAA47108  780 AENESEGDIPAERRGDDEDEGEIQAEGgevKGDedegeiq--ageggeVEGdedEGEIQAGEGGEVEGDEdeGEIQAge- 856  cattle
AAC18119  669 GENESEGDIQAERKGENESEGDIQAER---KGD---------------DEG---EGEIQAGEDGEMKGDE--GDLQA--- 722  bottlenosed dolphin
AAC16732  748 AEAESTGEMPGE-EGETAGEGETEEKS---GGEt-------------qPEG---EGETETQGKGEECEDE--NEAEG--- 802  human
AAD53121  760 GKEKQEGETESEGKDEQEGETEAEGKEadhEGEteaegkevehegeteAEGtedEQEGETEAEGKEVEQEgeTEAEGkev 839  Norway rat
CAA47108  857 --agEVEGDedegeiqageagevegDEDEGEIQAGEGGEVKGDEGeiqageagevegedgeveggedegeiqageggegE 934  cattle
AAC18119  723 ----ERKGD----------------DEGEGEIQAGEDGEMKGDDG----------------------------------E 748  bottlenosed dolphin
AAC16732  803 ------KGDn--------------eGEDEGEIHA-EDGEMKGNEG----------------------------------E 827  human
AAD53121  840 ehevETEAErketnhegeteaegkeADHEGETEAEGNVEHQGETEaegkvehegeteagekdehegqsetqaddtevkdG 919  Norway rat
CAA47108  935 TGEQELNAEIQGEAKDDEEGVDGEGGGDGGDSEDEEEEDEE-EEDEEEEEEEEEEEEEE------NEQPLSLEWPETRRK 1007 cattle
AAC18119  749 TGEQDLIADNQDDAKEDEKGIDGEEEGDGGESEDEEEEEEEgEEEEEQEEEEEEQEEEE------EEEPLSLEWPETRQK 822  bottlenosed dolphin
AAC16732  828 TESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEqEEEEEEEEQEEEEEEEEeeeekgNEEPLSLDWPETRQK 907  human
AAD53121  920 EGEAEANAEDQCETAQGEKGADGGGGSDGGDSEEEEDEEDE--EEEEEEEEEEEEEESE--------EPLSLEWPESRQK 989  Norway rat
CAA47108 1008 QAIYLFLLPIVFPLWLTVPDVRRLEAKKFFVITFLGSILWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDL 1087 cattle
AAC18119  823 QAIYLFLLPIVFPLWLTVPDVRRLEARKFFVITFLGSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDL 902  bottlenosed dolphin
AAC16732  908 QAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDL 987  human
AAD53121  990 QAIYLFLLPIVFPLWLTIPDVRRQEARKFFVITFLGSIIWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDL 1069 Norway rat
CAA47108 1088 ITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWMLFSLINGLQPVAVSSNGLFCAIVLLFLMLLFVISSIALCKWRMN 1167 cattle
AAC18119  903 ITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWMLFSFINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIALCKWRMN 982  bottlenosed dolphin
AAC16732  988 ITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMN 1067 human
AAD53121 1070 ITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINALQPIPVSSNGLFCAIVLLFLMLLFVIFSIASCKWRMN 1149 Norway rat
CAA47108 1168 KILGFTMFLLYFVFLIISVMLEDRIISCPVSV 1199 cattle
AAC18119  983 KILGFTMFLLYFVFLIISVMLEDRIISCPVSV 1014 bottlenosed dolphin
AAC16732 1068 KILGFTMFLLYFVFLIISVMLEDRIISCPVSV 1099 human
AAD53121 1150 KILGFTMFLLYFVFLVISVMLEDRIISCPVSV 1181 Norway rat
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