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Links from Conserved Domains

Items: 1 to 20 of 100

1.
Molecular Structure Image for cd10571

PH_beta_spectrin: Beta-spectrin pleckstrin homology (PH) domain

Beta spectrin binds actin and functions as a major component of the cytoskeleton underlying cellular...

2.
Molecular Structure Image for cd10569

FERM_C_Talin: FERM domain C-lobe/F3 of Talin

Talin (also called filopodin) plays an important role in initiating actin filament growth in motile ...

3.
4.
Molecular Structure Image for cd01273

PTB_CED-6: Cell death protein 6 homolog (CED-6/GULP1) Phosphotyrosine-binding (PTB) domain

CED6 (also known as GULP1: engulfment adaptor PTB domain containing 1) is an adaptor protein involve...

5.
Molecular Structure Image for cd01272

PTB1_Fe65: Fe65 N-terminal Phosphotyrosine-binding (PTB) domain

The neuronal adaptor protein Fe65 is involved in brain development, Alzheimer disease amyloid precur...

6.
Molecular Structure Image for cd01271

PTB2_Fe65: Fe65 C-terminal Phosphotyrosine-binding (PTB) domain

The neuronal adaptor protein Fe65 is involved in brain development, Alzheimer disease amyloid precur...

7.
8.
Molecular Structure Image for cd01269

PTB_TBC1D1_like: TBC1 domain family member 1 and related proteins Phosphotyrosine-binding (PTB) domain

The TBC1D1-like members here include TBC1D1, TBC1D4 (also called Akt substrate of 160 kDa or AS160),...

9.
Molecular Structure Image for cd01265

PH_TBC1D2A: TBC1 domain family member 2A pleckstrin homology (PH) domain

TBC1D2A (also called PARIS-1/Prostate antigen recognized and identified by SEREX 1 and ARMUS) contai...

10.
Molecular Structure Image for cd01264

PH_MELT_VEPH1: Melted pleckstrin homology (PH) domain

The melted protein (also called Ventricular zone expressed PH domain-containing protein homolog 1) i...

11.
Molecular Structure Image for cd01263

PH_anillin: Anillin Pleckstrin homology (PH) domain

Anillin (Rhotekin/RTKN; also called PLEKHK/Pleckstrin homology domain-containing family K) is an act...

12.
Molecular Structure Image for cd01261

PH_SOS: Son of Sevenless (SOS) Pleckstrin homology (PH) domain

SOS is a Ras guanine nucleotide exchange factor. SOS is thought to transmit signals from activated r...

13.
Molecular Structure Image for cd01260

PH_CNK_mammalian-like: Connector enhancer of KSR (Kinase suppressor of ras) (CNK) pleckstrin homology (PH) domain

CNK family members function as protein scaffolds, regulating the activity and the subcellular locali...

14.
Molecular Structure Image for cd01259

PH_APBB1IP: Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain

APBB1IP consists of a Ras-associated (RA) domain, a PH domain, a family-specific BPS region, and a C...

15.
Molecular Structure Image for cd01258

PHsplit_syntrophin: Syntrophin Split Pleckstrin homology (PH) domain

Syntrophins are scaffold proteins that associate with associate with the Duchenne muscular dystrophy...

16.
Molecular Structure Image for cd01257

PH_IRS: Insulin receptor substrate (IRS) pleckstrin homology (PH) domain

Insulin receptor substrate (IRS) molecules are mediators in insulin signaling and play a role in mai...

17.
Molecular Structure Image for cd01256

PH_dynamin: Dynamin pleckstrin homology (PH) domain

Dynamin is a GTPase that regulates endocytic vesicle formation. It has an N-terminal GTPase domain, ...

18.
Molecular Structure Image for cd01255

PH2_Tiam1_2: T-lymphoma invasion and metastasis 1 and 2 Pleckstrin Homology (PH) domain, C-terminal domain

Tiam1 activates Rac GTPases to induce membrane ruffling and cell motility while Tiam2 (also called S...

19.
Molecular Structure Image for cd01254

PH_PLD: Phospholipase D pleckstrin homology (PH) domain

PLD hydrolyzes phosphatidylcholine to phosphatidic acid (PtdOH), which can bind target proteins. PLD...

20.
Molecular Structure Image for cd01253

PH_ARHGAP21-like: ARHGAP21 and related proteins pleckstrin homology (PH) domain

ARHGAP family genes encode Rho/Rac/Cdc42-like GTPase activating proteins with a RhoGAP domain. These...

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