See
Genome Information for Mus musculus
Our goal was to identify gene expression patterns that correlated with treatment of established autoimmune alopecia in C3H/HeJ mice following alopecic graft transplantation
skin from 3 mice were taken at 6, 12 and, in some cases, 24 weeks of topical drug administration following grafting; mice were treated with ruxolitinib (jak1i), tofacitinib (jak3i), or control pbs
Overall design: 3 biological replicates were taken at each time point for each treatment modality
| Accession | PRJNA194536; GEO: GSE45514 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Xing L et al., "Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition.", Nat Med, 2014 Sep;20(9):1043-9 |
| Submission | Registration date: 26-Mar-2013
University of Iowa |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 2 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 1398131 |
| Data volume, Processed Mbytes | 32 |
| Data volume, Supplementary Mbytes | 112 |