6MBO: GLP Methyltransferase with Inhibitor EML741-P212121 Crystal Form

PDB ID: 6MBODownload
MMDB ID: 172722
PDB Deposition Date: 2018/8/30
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.591  Å
Source Organism:
Similar Structures:
Biological Unit for 6MBO: dimeric; determined by author
Molecular Components in 6MBO
Label Count Molecule
Proteins (2 molecules)
2
Histone-lysine N-methyltransferase Ehmt1
(Gene symbol: EHMT1)
Molecule annotation
Chemicals and Non-standard biopolymers (28 molecules)
1
4
2-cyclohexyl-7-methoxy-N-[1-(propan-2-yl)piperidin-4-yl]-8-[3-(pyrrolidin-1-yl)propoxy]-3H-1,4-benzodiazepin-5-amine2-cyclohexyl-7-methoxy-N-[1-(propan-2-yl)piperidin-4-yl]-8-[3-(pyrrolidin-1-yl)propoxy]-3H-1,4-benzodiazepin-5-amine
2
8
ZINC IONZINC ION
3
2
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
4
14
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303