5VSD: Structure of human GLP SET-domain (EHMT1) in complex with inhibitor 13

PDB ID: 5VSDDownload
MMDB ID: 152731
PDB Deposition Date: 2017/5/11
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 5VSD: dimeric; determined by author and by software (PISA)
Molecular Components in 5VSD
Label Count Molecule
Proteins (2 molecules)
2
Histone-lysine N-methyltransferase Ehmt1
(Gene symbol: EHMT1)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
2
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
2
8
ZINC IONZINC ION
3
2
6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)-N~2~-propylquinazoline-2,4-diamine6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)-N~2~-propylquinazoline-2,4-diamine
4
1
1,4-DIETHYLENE DIOXIDE1,4-DIETHYLENE DIOXIDE
5
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303