4C6L: Crystal structure of the dihydroorotase domain of human CAD bound to the inhibitor fluoroorotate at pH 6.0

PDB ID: 4C6LDownload
MMDB ID: 117177
PDB Deposition Date: 2013/9/18
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 4C6L: dimeric; determined by author and by software (PISA)
Molecular Components in 4C6L
Label Count Molecule
Proteins (2 molecules)
2
CAD Protein
(Gene symbol: CAD)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
4
ZINC IONZINC ION
2
4
FORMIC ACIDFORMIC ACID
3
2
5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303