NCBI
National Center for
Biotechnology Information
Search
2JKM:
Focal Adhesion Kinase catalytic domain in complex with bis-anilino pyrimidine inhibitor
PDB ID:
2JKM
Download
MMDB ID:
66527
PDB Deposition Date:
2008/8/28
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2.31 Å
Source Organism:
Gallus gallus
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2JKM: monomeric; determined by author and by software (PQS)
Molecular Components in 2JKM
Label
Count
Molecule
Protein (1 molecule)
A
1
Focal Adhesion Kinase 1
(Gene symbol:
PTK2
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-{[5-CHLORO-2-({(1E,4R)-2-METHOXY-4-[(3R)-3-(METHYLAMINO)PYRROLIDIN-1-YL]CYCLOHEXA-2,5-DIEN-1-YLIDENE}AMINO)PYRIMIDIN-4-YL]AMINO}-N-(1-METHYLETHYL)BENZENESULFONAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303