2G8E: Calpain 1 proteolytic core in complex with SNJ-1715, a cyclic hemiacetal-type inhibitor

PDB ID: 2G8EDownload
MMDB ID: 39345
PDB Deposition Date: 2006/3/2
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 2G8E: monomeric; determined by author
Molecular Components in 2G8E
Label Count Molecule
Protein (1 molecule)
1
Calpain-1 Catalytic Subunit
(Gene symbol: Capn1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
CALCIUM IONCALCIUM ION
2
1
N-[(2S)-1,4-dihydroxybutan-2-yl]-N~2~-(phenylcarbamothioyl)-L-leucinamideN-[(2S)-1,4-dihydroxybutan-2-yl]-N~2~-(phenylcarbamothioyl)-L-leucinamide
3
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303