|
Name |
Accession |
Description |
Interval |
E-value |
| CAP_GLY |
pfam01302 |
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ... |
213-277 |
1.04e-34 |
|
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 460154 [Multi-domain] Cd Length: 65 Bit Score: 126.75 E-value: 1.04e-34
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907165170 213 VGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKV 277
Cdd:pfam01302 1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
|
|
| CAP_GLY |
pfam01302 |
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ... |
60-124 |
5.13e-31 |
|
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 460154 [Multi-domain] Cd Length: 65 Bit Score: 116.35 E-value: 5.13e-31
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907165170 60 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
Cdd:pfam01302 1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
|
|
| CAP_GLY |
smart01052 |
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ... |
213-278 |
3.19e-28 |
|
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 214997 [Multi-domain] Cd Length: 68 Bit Score: 108.44 E-value: 3.19e-28
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907165170 213 VGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPKYGLFAPVHKVT 278
Cdd:smart01052 1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
|
|
| CAP_GLY |
smart01052 |
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ... |
60-125 |
2.16e-27 |
|
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.
Pssm-ID: 214997 [Multi-domain] Cd Length: 68 Bit Score: 106.13 E-value: 2.16e-27
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907165170 60 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLKGIFTRPSKLT 125
Cdd:smart01052 1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
502-1239 |
7.35e-20 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 96.66 E-value: 7.35e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 502 ELEKDL------ALRAQEVAELRRRLEsskppgDVDMSLSLLqEISALQEKLEAIhtdhQGEMTSLKEhfgaREEAFQKE 575
Cdd:TIGR02168 197 ELERQLkslerqAEKAERYKELKAELR------ELELALLVL-RLEELREELEEL----QEELKEAEE----ELEELTAE 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 576 IKALHTATEKLSKENESLRSKLDHANKENSDVIALwKSKLETAIASHQQAMEELKVSFSKGigtdSAEFAELKTQIERLR 655
Cdd:TIGR02168 262 LQELEEKLEELRLEVSELEEEIEELQKELYALANE-ISRLEQQKQILRERLANLERQLEEL----EAQLEELESKLDELA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 656 LDY---QHEIESLQSKQDSERSAHAKEMETMQAkLMKIIKEKEDSLEAVKARLDSAEDQ------HLVEMEDTLNKLQEA 726
Cdd:TIGR02168 337 EELaelEEKLEELKEELESLEAELEELEAELEE-LESRLEELEEQLETLRSKVAQLELQiaslnnEIERLEARLERLEDR 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 727 EIKANSITKELQEK--ELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLS 804
Cdd:TIGR02168 416 RERLQQEIEELLKKleEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 805 SELEKLRENLTDMEAKFKEKDDRED------QLVKAKEK----LENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQ 874
Cdd:TIGR02168 496 RLQENLEGFSEGVKALLKNQSGLSGilgvlsELISVDEGyeaaIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTF 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 875 LKLTKANENAsfLQKSIGEVtLKAEQSQQQAARKHEEEKKELEEKLLE--LEKKMETSYNQCQDLKAKYE---------- 942
Cdd:TIGR02168 576 LPLDSIKGTE--IQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYllGGVLVVDDLDNALELAKKLRpgyrivtldg 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 943 ----------KASSETKTKheeiLQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKaaQTAEDAMQIMEQMTK 1012
Cdd:TIGR02168 653 dlvrpggvitGGSAKTNSS----ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELE--EELEQLRKELEELSR 726
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1013 EKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENV 1092
Cdd:TIGR02168 727 QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALD 806
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1093 KLAEELGRTRDEVtsHQKLEEERSVLNNqlLEMKKRESEfrkDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLR 1172
Cdd:TIGR02168 807 ELRAELTLLNEEA--ANLRERLESLERR--IAATERRLE---DLEEQIEELSEDIESLAAEIEELEELIEELESELEALL 879
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907165170 1173 GENATAKSLhsvVQTLESDKVKLELKVKNLELQLKENKRQLSSSsgnTDAQAEEDERAQESQIDFLN 1239
Cdd:TIGR02168 880 NERASLEEA---LALLRSELEELSEELRELESKRSELRRELEEL---REKLAQLELRLEGLEVRIDN 940
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
351-1076 |
4.69e-18 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 90.50 E-value: 4.69e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALArdghDQHVLELEAKMDQLRTMVEAADREKVELLNQL 430
Cdd:TIGR02168 257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL----EQQKQILRERLANLERQLEELEAQLEELESKL 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 431 EEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELE---KDL 507
Cdd:TIGR02168 333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEarlERL 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 508 ALRAQEVAELRRRLESSKPPGDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQK----------EIK 577
Cdd:TIGR02168 413 EDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAaerelaqlqaRLD 492
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 578 ALHTATEKLSKENESLRSKLDHANKENSDVIAL---------WKSKLETAIASHQQA--MEELK-----VSFSKGIGTDS 641
Cdd:TIGR02168 493 SLERLQENLEGFSEGVKALLKNQSGLSGILGVLselisvdegYEAAIEAALGGRLQAvvVENLNaakkaIAFLKQNELGR 572
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 642 AEFAELK----TQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKI-IKEKEDSLEAVKARLDSAE-----DQ 711
Cdd:TIGR02168 573 VTFLPLDsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlVVDDLDNALELAKKLRPGYrivtlDG 652
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 712 HLV----------------------EMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLK 769
Cdd:TIGR02168 653 DLVrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALR 732
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 770 EKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKfkekddredqlvkaKEKLENDIAEIMKMS 849
Cdd:TIGR02168 733 KDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE--------------IEELEAQIEQLKEEL 798
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 850 GDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARkheeeKKELEEKLLELEKKMET 929
Cdd:TIGR02168 799 KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES-----LAAEIEELEELIEELES 873
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 930 SYNQCQDLKAKYEKASSEtktkHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKA------AQTAEDA 1003
Cdd:TIGR02168 874 ELEALLNERASLEEALAL----LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVridnlqERLSEEY 949
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907165170 1004 MQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQA 1076
Cdd:TIGR02168 950 SLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
333-1228 |
5.88e-17 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 87.12 E-value: 5.88e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 333 GLLTETSSRYARKISGTTALQEALK--EKQQHIEQLLAERDLERAEVAKAtshvGEIEQELALARDGHDQHVLELEAKMD 410
Cdd:PTZ00121 1098 GKAEEAKKTETGKAEEARKAEEAKKkaEDARKAEEARKAEDARKAEEARK----AEDAKRVEIARKAEDARKAEEARKAE 1173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 411 QLRTMVEAADREKVellnQLEEEKRKVEDLQfrveeesitkgdletqtKLEHARTKEleqsllfEKTKADKLQRELEDTR 490
Cdd:PTZ00121 1174 DAKKAEAARKAEEV----RKAEELRKAEDAR-----------------KAEAARKAE-------EERKAEEARKAEDAKK 1225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 491 VATVSeksRIMELEKDlALRAQEVAELRRRLESSKPPGDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREE 570
Cdd:PTZ00121 1226 AEAVK---KAEEAKKD-AEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEK 1301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 571 AFQKEIKAL---HTATEKLSKENESLRSKLDHANKENSDVialwKSKLETAIASHQQAMEELKVSFSKgigtdsAEFAEL 647
Cdd:PTZ00121 1302 KKADEAKKKaeeAKKADEAKKKAEEAKKKADAAKKKAEEA----KKAAEAAKAEAEAAADEAEAAEEK------AEAAEK 1371
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 648 KTQIERLRLDyqheieslQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAE 727
Cdd:PTZ00121 1372 KKEEAKKKAD--------AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEA 1443
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 728 IKANSITKELQEKelvltglQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQfNVLSSEL 807
Cdd:PTZ00121 1444 KKADEAKKKAEEA-------KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEA-KKKADEA 1515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 808 EKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDiaEIMKMSGDNSSQLTKMNDElrlKERSVEELQLKLTKANENASFL 887
Cdd:PTZ00121 1516 KKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAD--ELKKAEELKKAEEKKKAEE---AKKAEEDKNMALRKAEEAKKAE 1590
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 888 QKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEilqnlqkmladtE 967
Cdd:PTZ00121 1591 EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEE------------E 1658
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 968 DKLKAAQEANRDlmqdmEELKTQADKAKAAQtaEDAMQIMEQMTKEKTET--LASLEDTKQTNARLQNELDTLKENNLKT 1045
Cdd:PTZ00121 1659 NKIKAAEEAKKA-----EEDKKKAEEAKKAE--EDEKKAAEALKKEAEEAkkAEELKKKEAEEKKKAEELKKAEEENKIK 1731
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1046 VEELNKSKEllsVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQ---- 1121
Cdd:PTZ00121 1732 AEEAKKEAE---EDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFdnfa 1808
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1122 -LLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVK 1200
Cdd:PTZ00121 1809 nIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEAD 1888
|
890 900
....*....|....*....|....*...
gi 1907165170 1201 NLElqlKENKRQLSSSSGNTDAQAEEDE 1228
Cdd:PTZ00121 1889 EIE---KIDKDDIEREIPNNNMAGKNND 1913
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
344-1130 |
6.97e-17 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 86.66 E-value: 6.97e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 344 RKISGTTALQEALKEKQQH---IEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAK----MDQLRTMV 416
Cdd:TIGR02169 217 LKEKREYEGYELLKEKEALerqKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeQLRVKEKI 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 417 EAADREKVELLNQLEEEKRKVEDLqfrveEESITKGDLETQTKLEHARtkELEQSLLFEKTKADKLQRELEDTRVATVSE 496
Cdd:TIGR02169 297 GELEAEIASLERSIAEKERELEDA-----EERLAKLEAEIDKLLAEIE--ELEREIEEERKRRDKLTEEYAELKEELEDL 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 497 KSRIMELEKDLALRAQEVAELRRRLESSKPPGDvdmslSLLQEISALQEKLEAIHT---DHQGEMTSLKE---HFGAREE 570
Cdd:TIGR02169 370 RAELEEVDKEFAETRDELKDYREKLEKLKREIN-----ELKRELDRLQEELQRLSEelaDLNAAIAGIEAkinELEEEKE 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 571 AFQKEIKA----LHTATEKLSKENES---LRSKLDHANKENSDVialwKSKLETAIASHQQAMEELKVSFS--KGIGTDS 641
Cdd:TIGR02169 445 DKALEIKKqewkLEQLAADLSKYEQElydLKEEYDRVEKELSKL----QRELAEAEAQARASEERVRGGRAveEVLKASI 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 642 AEFAELKTQIERLRLDYQHEIESLQSK-------QDSERSAHA----KEMETMQAKLMKIIKEKEDSLEAVKARLDSAED 710
Cdd:TIGR02169 521 QGVHGTVAQLGSVGERYATAIEVAAGNrlnnvvvEDDAVAKEAiellKRRKAGRATFLPLNKMRDERRDLSILSEDGVIG 600
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 711 Q--HLVEME------------DTL--NKLQEA-----EIKANSITKELQEKELVLTG--------------LQDSLNQVN 755
Cdd:TIGR02169 601 FavDLVEFDpkyepafkyvfgDTLvvEDIEAArrlmgKYRMVTLEGELFEKSGAMTGgsraprggilfsrsEPAELQRLR 680
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 756 QVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDdredqlvkak 835
Cdd:TIGR02169 681 ERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE---------- 750
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 836 EKLENDIAEimkmsgdnssqLTKMNDELRLKERSVEELQLKLT--KANENASFLQKSIGEVT-LKAEQSQQQAARKH-EE 911
Cdd:TIGR02169 751 QEIENVKSE-----------LKELEARIEELEEDLHKLEEALNdlEARLSHSRIPEIQAELSkLEEEVSRIEARLREiEQ 819
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 912 EKKELEEKLLELEKKMETSYNQCQDLKAKyekassetKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQA 991
Cdd:TIGR02169 820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQ--------IKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKER 891
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 992 DKAKAAqtaedamqiMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENnLKTVEELNKSKELLSVENQKMEEFKKEIE 1071
Cdd:TIGR02169 892 DELEAQ---------LRELERKIEELEAQIEKKRKRLSELKAKLEALEEE-LSEIEDPKGEDEEIPEEELSLEDVQAELQ 961
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907165170 1072 TLKQAaaqksqqLSALQEENVK----LAEELGRTRDEVTSHQKLEEERSVLNNQL--LEMKKRES 1130
Cdd:TIGR02169 962 RVEEE-------IRALEPVNMLaiqeYEEVLKRLDELKEKRAKLEEERKAILERIeeYEKKKREV 1019
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
386-1148 |
8.73e-17 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 86.65 E-value: 8.73e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 386 EIEQELALAR-DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLE-------EEKRKVEDLQFRVEEESITKGDLETQ 457
Cdd:TIGR02168 224 ELELALLVLRlEELREELEELQEELKEAEEELEELTAELQELEEKLEelrlevsELEEEIEELQKELYALANEISRLEQQ 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 458 TKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKppgdvdmslSLL 537
Cdd:TIGR02168 304 KQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE---------SRL 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 538 QEISALQEKLEAIHTDHQGEMTSLKEHFGAREEafqkEIKALHTATEKLSKENESLRSKLDHANKEnsdvialwksKLET 617
Cdd:TIGR02168 375 EELEEQLETLRSKVAQLELQIASLNNEIERLEA----RLERLEDRRERLQQEIEELLKKLEEAELK----------ELQA 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 618 AIASHQQAMEELKVSFSKGIgTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERS----------------AHAKEME 681
Cdd:TIGR02168 441 ELEELEEELEELQEELERLE-EALEELREELEEAEQALDAAERELAQLQARLDSLERlqenlegfsegvkallKNQSGLS 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 682 TMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKANSITKELqekeLVLTGLQDSLNQVN--QVKE 759
Cdd:TIGR02168 520 GILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTF----LPLDSIKGTEIQGNdrEILK 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 760 TLEKELQTLKE--KFASTSEEAVS---AQTRMQDTV----NKLHQKEEQFNVLS-------------------------- 804
Cdd:TIGR02168 596 NIEGFLGVAKDlvKFDPKLRKALSyllGGVLVVDDLdnalELAKKLRPGYRIVTldgdlvrpggvitggsaktnssiler 675
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 805 -SELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANEN 883
Cdd:TIGR02168 676 rREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 884 ASFLQKSIGEVTLKAEQSQQQAARkheeekkeLEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEiLQNLQKML 963
Cdd:TIGR02168 756 LTELEAEIEELEERLEEAEEELAE--------AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE-AANLRERL 826
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 964 ADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQtaEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNL 1043
Cdd:TIGR02168 827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEI--EELEELIEELESELEALLNERASLEEALALLRSELEELSEELR 904
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1044 KTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEvtSHQKLEEERSVLNNQLL 1123
Cdd:TIGR02168 905 ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIED--DEEEARRRLKRLENKIK 982
|
810 820 830 840
....*....|....*....|....*....|....*....|..
gi 1907165170 1124 EM--------------KKRESEFRK---DADEEKASLQKSIS 1148
Cdd:TIGR02168 983 ELgpvnlaaieeyeelKERYDFLTAqkeDLTEAKETLEEAIE 1024
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
568-1226 |
5.12e-15 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 80.50 E-value: 5.12e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 568 REEAFQKEIKALHTATEKLSKENEslrskldhaNKENSDVIALWKSKLE-TAIASHQQAMEELKVSFSKGIGTDSAEFAE 646
Cdd:TIGR02169 185 NIERLDLIIDEKRQQLERLRRERE---------KAERYQALLKEKREYEgYELLKEKEALERQKEAIERQLASLEEELEK 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 647 LKTQIERLRLDYqHEIESLqskqdseRSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEA 726
Cdd:TIGR02169 256 LTEEISELEKRL-EEIEQL-------LEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 727 EI-------KANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLH----- 794
Cdd:TIGR02169 328 EAeidkllaEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINelkre 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 795 --QKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEE 872
Cdd:TIGR02169 408 ldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSK 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 873 LQLKLTKANENAS--------------FLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLk 938
Cdd:TIGR02169 488 LQRELAEAEAQARaseervrggraveeVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIEL- 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 939 AKYEKASSET-----KTKHEEILQNLQKM---------LADTEDKLKAA-------------QEANRDLM---------- 981
Cdd:TIGR02169 567 LKRRKAGRATflplnKMRDERRDLSILSEdgvigfavdLVEFDPKYEPAfkyvfgdtlvvedIEAARRLMgkyrmvtleg 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 982 ---------------QDMEELKTQADKAKAAQTAED----------AMQIMEQMTKEKTETLASLEDTKQTNARLQNELD 1036
Cdd:TIGR02169 647 elfeksgamtggsraPRGGILFSRSEPAELQRLRERleglkrelssLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1037 TLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTR-DEVTSH-QKLEEE 1114
Cdd:TIGR02169 727 QLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRiPEIQAElSKLEEE 806
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1115 RSVLNNQLLEMKKRES-----------------EFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGEnat 1177
Cdd:TIGR02169 807 VSRIEARLREIEQKLNrltlekeylekeiqelqEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR--- 883
|
730 740 750 760
....*....|....*....|....*....|....*....|....*....
gi 1907165170 1178 AKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEE 1226
Cdd:TIGR02169 884 LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
356-1059 |
8.74e-15 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 79.78 E-value: 8.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 356 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELAL----ARDGHD---QHVLELEAKMDQLRTMVEAADREKV 424
Cdd:pfam15921 262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIiqeqARNQNSmymRQLSDLESTVSQLRSELREAKRMYE 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 425 ELLNQLEEE---------KRKVEDLQFRVEEESItkgDLETQTKLEHARTKELEQSLLFEKTK------------ADKLQ 483
Cdd:pfam15921 342 DKIEELEKQlvlanseltEARTERDQFSQESGNL---DDQLQKLLADLHKREKELSLEKEQNKrlwdrdtgnsitIDHLR 418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 484 RELEDTRVatvsEKSRIMELEKDLALRAQ------------------EVAELRRRLESSKppgdvDMSLSLLQEISALQE 545
Cdd:pfam15921 419 RELDDRNM----EVQRLEALLKAMKSECQgqmerqmaaiqgknesleKVSSLTAQLESTK-----EMLRKVVEELTAKKM 489
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 546 KLEAIHTDHQGEMTSLKEHFGAREeAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIAL-----WKSKLETAIA 620
Cdd:pfam15921 490 TLESSERTVSDLTASLQEKERAIE-ATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALklqmaEKDKVIEILR 568
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 621 SHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQhEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEA 700
Cdd:pfam15921 569 QQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ-EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRA 647
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 701 VKaRLDSAEDQHLVEMEDTLNKL----QEAEIKANSITKELQEKELVLTGLQdslNQVNQVKETLEKELQTLKEKFASTS 776
Cdd:pfam15921 648 VK-DIKQERDQLLNEVKTSRNELnslsEDYEVLKRNFRNKSEEMETTTNKLK---MQLKSAQSELEQTRNTLKSMEGSDG 723
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 777 EeAVSAQTRMQDTVNKlhqKEEQFNVLSSELEKLRENLTDMEakfKEKDDREDQLVKAKEKLENDIAEIMKMSGDNssql 856
Cdd:pfam15921 724 H-AMKVAMGMQKQITA---KRGQIDALQSKIQFLEEAMTNAN---KEKHFLKEEKNKLSQELSTVATEKNKMAGEL---- 792
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 857 tkmnDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEkllelekkmeTSYNQCQD 936
Cdd:pfam15921 793 ----EVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQG----------PGYTSNSS 858
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 937 LKAKYEKASSETKTkHEEI--LQNLQKMLADTEDKLKAAQE-ANRDLMQDMEELKTQADKakaaqtaEDAMQIMEQMTKE 1013
Cdd:pfam15921 859 MKPRLLQPASFTRT-HSNVpsSQSTASFLSHHSRKTNALKEdPTRDLKQLLQELRSVINE-------EPTVQLSKAEDKG 930
|
730 740 750 760
....*....|....*....|....*....|....*....|....*....
gi 1907165170 1014 KTETLASLEDTKQ---TNARLQNELDTLKENNLKTveELNKSKELLSVE 1059
Cdd:pfam15921 931 RAPSLGALDDRVRdciIESSLRSDICHSSSNSLQT--EGSKSSETCSRE 977
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
645-1174 |
8.76e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 79.98 E-value: 8.76e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 645 AELKTQIERLR------LDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQH------ 712
Cdd:COG1196 196 GELERQLEPLErqaekaERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELeelrle 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 713 LVEMEDTLNKLQEAEikaNSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNK 792
Cdd:COG1196 276 LEELELELEEAQAEE---YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 793 LHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEE 872
Cdd:COG1196 353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAE 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 873 LQLKLTKANENASFLQKSIGEVTLKAEQ--SQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKT 950
Cdd:COG1196 433 LEEEEEEEEEALEEAAEEEAELEEEEEAllELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 951 KHEEILQNLQ----KMLADTEDKLKAAQEA------NRDLMQDMEELKTQADKAKAAQTAEDAMQIMEQMTKEKTETLAS 1020
Cdd:COG1196 513 ALLLAGLRGLagavAVLIGVEAAYEAALEAalaaalQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAAL 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1021 L------------EDTKQTNARLQNELDTLKENNLKT--------------VEELNKSKELLSVENQKMEE---FKKEIE 1071
Cdd:COG1196 593 ArgaigaavdlvaSDLREADARYYVLGDTLLGRTLVAarleaalrravtlaGRLREVTLEGEGGSAGGSLTggsRRELLA 672
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1072 TLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISLTS 1151
Cdd:COG1196 673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752
|
570 580
....*....|....*....|...
gi 1907165170 1152 ALLTEKDAELEKLRNEVTVLRGE 1174
Cdd:COG1196 753 LEELPEPPDLEELERELERLERE 775
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
358-756 |
2.08e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.56 E-value: 2.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 358 EKQQHIEQLlaerdleRAEVAKATSHVGEIEQELALARDGHDqhvlELEAKMDQLRTMVEAADREKVELLNQLEEEKRKV 437
Cdd:TIGR02168 674 ERRREIEEL-------EEKIEELEEKIAELEKALAELRKELE----ELEEELEQLRKELEELSRQISALRKDLARLEAEV 742
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 438 EDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRAQEVAEL 517
Cdd:TIGR02168 743 EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 518 RRRLESS-KPPGDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSK 596
Cdd:TIGR02168 823 RERLESLeRRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 597 LDHANKENSDVIALwKSKLETAIASHQQAMEELKVsfskgigtdsaefaELKTQIERLRLDYQ---HEIESLQSKQDSER 673
Cdd:TIGR02168 903 LRELESKRSELRRE-LEELREKLAQLELRLEGLEV--------------RIDNLQERLSEEYSltlEEAEALENKIEDDE 967
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 674 S---AHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHlVEMEDTLNKLQEAEIKANSITKELqekelvltgLQDS 750
Cdd:TIGR02168 968 EearRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQK-EDLTEAKETLEEAIEEIDREARER---------FKDT 1037
|
....*.
gi 1907165170 751 LNQVNQ 756
Cdd:TIGR02168 1038 FDQVNE 1043
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
351-893 |
3.74e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 77.67 E-value: 3.74e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDG---HDQHVLELEAKMDQLRTMVEAADREKVELL 427
Cdd:COG1196 243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEeyeLLAELARLEQDIARLEERRRELEERLEELE 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 428 NQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDL 507
Cdd:COG1196 323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 508 ALRAQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLS 587
Cdd:COG1196 403 EELEEAEEALLERLERLE-----EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 588 KENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIEslqs 667
Cdd:COG1196 478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVV---- 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 668 kQDSERSAHAKEmetmQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKANSITKELQEKELVLTGL 747
Cdd:COG1196 554 -EDDEVAAAAIE----YLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 748 QDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQfnvLSSELEKLRENLTDMEAKFKEKDDR 827
Cdd:COG1196 629 AARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE---LEELAERLAEEELELEEALLAEEEE 705
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907165170 828 EDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGE 893
Cdd:COG1196 706 ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
698-1099 |
3.94e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 77.67 E-value: 3.94e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 698 LEAVKARLDSAEDqHLVEMEDTLNKLQ-EAEI--KANSITKELQEKELVLTGLQDslnqvnqvkETLEKELQTLKEKFAS 774
Cdd:COG1196 181 LEATEENLERLED-ILGELERQLEPLErQAEKaeRYRELKEELKELEAELLLLKL---------RELEAELEELEAELEE 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 775 TSEEAVSAQTRMQDtvnklhqkeeqfnvLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSS 854
Cdd:COG1196 251 LEAELEELEAELAE--------------LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 855 QLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARkheeekkeleekllelekkmetsynqc 934
Cdd:COG1196 317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE--------------------------- 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 935 qdLKAKYEKASSETKTKHEEILQNLQKmLADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTAEDAmqimeqmtkEK 1014
Cdd:COG1196 370 --AEAELAEAEEELEELAEELLEALRA-AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE---------EE 437
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1015 TETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKL 1094
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLA 517
|
....*
gi 1907165170 1095 AEELG 1099
Cdd:COG1196 518 GLRGL 522
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
351-903 |
5.65e-14 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 77.00 E-value: 5.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELalardghdQHVLELEAKMDQLRTMVEAADREKVELLNQL 430
Cdd:PRK02224 210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERR--------EELETLEAEIEDLRETIAETEREREELAEEV 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 431 EEEKRKVEDLQFRVEeesitkgDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRV---ATVSEKSRIMELEKDL 507
Cdd:PRK02224 282 RDLRERLEELEEERD-------DLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVaaqAHNEEAESLREDADDL 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 508 ALRAQEVAELRRRLESskppgDVDMSLSLLQEISALQEKLEAihtdhqgEMTSLKEHFGAREEAFqkeikalhtatEKLS 587
Cdd:PRK02224 355 EERAEELREEAAELES-----ELEEAREAVEDRREEIEELEE-------EIEELRERFGDAPVDL-----------GNAE 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 588 KENESLRSKLDHANKENSDVIALWKSkLETAIASHQQAMEELKV----------SFSKGIGTDSAEFAELKTQIERLRLd 657
Cdd:PRK02224 412 DFLEELREERDELREREAELEATLRT-ARERVEEAEALLEAGKCpecgqpvegsPHVETIEEDRERVEELEAELEDLEE- 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 658 yqhEIESLQSKQDSERSAH--AKEMETMQAK---LMKIIKEKEDSLEAVKARLDS---AEDQHLVEMEDTLNKLQEAEIK 729
Cdd:PRK02224 490 ---EVEEVEERLERAEDLVeaEDRIERLEERredLEELIAERRETIEEKRERAEElreRAAELEAEAEEKREAAAEAEEE 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 730 ANSITKELQEKELVLTGLQDSLNQVNQVKETLEK------ELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFN-- 801
Cdd:PRK02224 567 AEEAREEVAELNSKLAELKERIESLERIRTLLAAiadaedEIERLREKREALAELNDERRERLAEKRERKRELEAEFDea 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 802 ---VLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEImkmsgdnssqltkmnDELRLKERSVEELQLKLT 878
Cdd:PRK02224 647 rieEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEEL---------------EELRERREALENRVEALE 711
|
570 580
....*....|....*....|....*
gi 1907165170 879 KANENASFLQKSIGEvtLKAEQSQQ 903
Cdd:PRK02224 712 ALYDEAEELESMYGD--LRAELRQR 734
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
340-847 |
1.14e-13 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 76.26 E-value: 1.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 340 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELaLARDGHDQHVLELEAKMDQLRTMVEAA 419
Cdd:PRK03918 179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELESLEGSKRKL 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 420 DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKAD------KLQRELEDTRvat 493
Cdd:PRK03918 258 EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRleeeinGIEERIKELE--- 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 494 vSEKSRIMELEKdlalraqEVAELRRRLESSKPpgdvdmSLSLLQEISALQEKLEaihtdhqgemtSLKEHFGARE-EAF 572
Cdd:PRK03918 335 -EKEERLEELKK-------KLKELEKRLEELEE------RHELYEEAKAKKEELE-----------RLKKRLTGLTpEKL 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 573 QKEIKALHTATEKLSKENESLRSKLDHANKENSD----VIALWKSKLETAIASH---QQAMEELKVSFSKGIGTDSAEFA 645
Cdd:PRK03918 390 EKELEELEKAKEEIEEEISKITARIGELKKEIKElkkaIEELKKAKGKCPVCGReltEEHRKELLEEYTAELKRIEKELK 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 646 ELKTQIERLRLDYQhEIESLQSKQDSERSAH--AKEMETMQAKLMKI----IKEKEDSLEAVKARLDSAEDQhLVEMEDT 719
Cdd:PRK03918 470 EIEEKERKLRKELR-ELEKVLKKESELIKLKelAEQLKELEEKLKKYnleeLEKKAEEYEKLKEKLIKLKGE-IKSLKKE 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 720 LNKLQEAEIKANSITKELQEKELVLTGLQDSLNQ-----VNQVKETL----------------EKELQTLKEKFASTSEE 778
Cdd:PRK03918 548 LEKLEELKKKLAELEKKLDELEEELAELLKELEElgfesVEELEERLkelepfyneylelkdaEKELEREEKELKKLEEE 627
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 779 AVSAQTRMQDTVNKLHQK------------EEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIM 846
Cdd:PRK03918 628 LDKAFEELAETEKRLEELrkeleelekkysEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
|
.
gi 1907165170 847 K 847
Cdd:PRK03918 708 K 708
|
|
| NIP100 |
COG5244 |
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ... |
211-271 |
1.43e-13 |
|
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 227569 [Multi-domain] Cd Length: 669 Bit Score: 75.49 E-value: 1.43e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907165170 211 LKVGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLF 271
Cdd:COG5244 4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
335-845 |
2.64e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.97 E-value: 2.64e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 335 LTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALA----------RDGHDQHVLE 404
Cdd:COG1196 290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAeeeleeaeaeLAEAEEALLE 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 405 LEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQR 484
Cdd:COG1196 370 AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 485 ELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKPPGDVDMSLSLLQE-------ISALQEKLEAIHTDHQGE 557
Cdd:COG1196 450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvkAALLLAGLRGLAGAVAVL 529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 558 MTSLKEHFGAREEAFQKEIKALHTATE----------KLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAME 627
Cdd:COG1196 530 IGVEAAYEAALEAALAAALQNIVVEDDevaaaaieylKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 628 ELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDS 707
Cdd:COG1196 610 EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 708 AEDQHLVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQtrmQ 787
Cdd:COG1196 690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL---E 766
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907165170 788 DTVNKLHQKEEQF---NVLS-SELEKLRENLTDMEAKfkekddREDqLVKAKEKLENDIAEI 845
Cdd:COG1196 767 RELERLEREIEALgpvNLLAiEEYEELEERYDFLSEQ------RED-LEEARETLEEAIEEI 821
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
709-1262 |
5.83e-13 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 74.06 E-value: 5.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 709 EDQHLVEMEDTLNKLQEAEIKANSITKELQEKElvltglqdslNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQD 788
Cdd:pfam01576 3 QEEEMQAKEEELQKVKERQQKAESELKELEKKH----------QQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 789 TVNKLH-------QKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQL----VKAKEKLENDIAEIMKMSGDNSsqlt 857
Cdd:pfam01576 73 LEEILHelesrleEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLqlekVTTEAKIKKLEEDILLLEDQNS---- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 858 KMNDELRLKERSVEELQLKLTKANENASFLQK---------SIGEVTLKAEQSQQQAARKHEEEKKELEEKLLElekkme 928
Cdd:pfam01576 149 KLSKERKLLEERISEFTSNLAEEEEKAKSLSKlknkheamiSDLEERLKKEEKGRQELEKAKRKLEGESTDLQE------ 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 929 tsynQCQDLKAKYEKASSETKTKHEEiLQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTAEDAMQ--I 1006
Cdd:pfam01576 223 ----QIAELQAQIAELRAQLAKKEEE-LQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRrdL 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1007 MEQMTKEKTEtlasLEDTKQTNArLQNELDTLKENNL----KTVEELNKS-----KELLSVENQKMEEFKKEIETLKQAA 1077
Cdd:pfam01576 298 GEELEALKTE----LEDTLDTTA-AQQELRSKREQEVtelkKALEEETRSheaqlQEMRQKHTQALEELTEQLEQAKRNK 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1078 AQKSQQLSALQEENVKLAEELgrtRDEVTSHQKLEEERSVLNNQLLEMKKRESE---FRKDADEEKASLQKSISLTSALL 1154
Cdd:pfam01576 373 ANLEKAKQALESENAELQAEL---RTLQQAKQDSEHKRKKLEGQLQELQARLSEserQRAELAEKLSKLQSELESVSSLL 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1155 TEKDAELEKLRNEVTVLRGENATAKSLhsvVQTLESDKVKLELKVKNLELQLKENKRQLSsssgntdaQAEEDERAQESQ 1234
Cdd:pfam01576 450 NEAEGKNIKLSKDVSSLESQLQDTQEL---LQEETRQKLNLSTRLRQLEDERNSLQEQLE--------EEEEAKRNVERQ 518
|
570 580
....*....|....*....|....*...
gi 1907165170 1235 IDFLNSVIVDLQRKNQDLKMKVEMMSEA 1262
Cdd:pfam01576 519 LSTLQAQLSDMKKKLEEDAGTLEALEEG 546
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
503-1269 |
1.14e-12 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 72.84 E-value: 1.14e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 503 LEKDLALRAQEVAELRRRLESSKPPGDvDMSLSLLQEISALQEKLEAIHTDHQGeMTSLKEhfgaREEAFQKEIKalhTA 582
Cdd:pfam15921 76 IERVLEEYSHQVKDLQRRLNESNELHE-KQKFYLRQSVIDLQTKLQEMQMERDA-MADIRR----RESQSQEDLR---NQ 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 583 TEKLSKENESLRS-KLDHANKENSDVIALWKSKLetaiaSHQQAMEElkvsfskgigtdsaefaelktqIERLRLDYQHE 661
Cdd:pfam15921 147 LQNTVHELEAAKClKEDMLEDSNTQIEQLRKMML-----SHEGVLQE----------------------IRSILVDFEEA 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 662 IESLQSKQDSERSAHAKEMETmqaKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLqeaeikansitkelqekE 741
Cdd:pfam15921 200 SGKKIYEHDSMSTMHFRSLGS---AISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKI-----------------E 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 742 LVLTGLQDslnQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQ----DTVNKLHQKEEQFNVLSSELEKLRENLTDM 817
Cdd:pfam15921 260 LLLQQHQD---RIEQLISEHEVEITGLTEKASSARSQANSIQSQLEiiqeQARNQNSMYMRQLSDLESTVSQLRSELREA 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 818 EAKFKEK-DDREDQLVKAKEKLENDIAE---IMKMSGDNSSQLTKMNDEL--RLKERSVEELQLKLTKANENASFLqkSI 891
Cdd:pfam15921 337 KRMYEDKiEELEKQLVLANSELTEARTErdqFSQESGNLDDQLQKLLADLhkREKELSLEKEQNKRLWDRDTGNSI--TI 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 892 GEVTLKAEQSQQQAARkheeekkeleeklleLEKKMETSYNQCQDlKAKYEKASSETKTKHEEILQNLQKMLADTEDKL- 970
Cdd:pfam15921 415 DHLRRELDDRNMEVQR---------------LEALLKAMKSECQG-QMERQMAAIQGKNESLEKVSSLTAQLESTKEMLr 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 971 KAAQEANRDLMQDMEELKTQADKAKAAQTAEDAMqimEQMTKEKTETLASLEDTKQTNARLQNELDTLKenNLKTveELN 1050
Cdd:pfam15921 479 KVVEELTAKKMTLESSERTVSDLTASLQEKERAI---EATNAEITKLRSRVDLKLQELQHLKNEGDHLR--NVQT--ECE 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1051 KSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERsvlnnqllEMKKRES 1130
Cdd:pfam15921 552 ALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKK--------DAKIREL 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1131 EFR-KDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGE-NATAKSLHSVVQTLESDKVKLELKVKNLELQLKE 1208
Cdd:pfam15921 624 EARvSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNElNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKS 703
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907165170 1209 NKRQLSSSSGNTDAQAEEDERAQESQIDFLNSVIVdlQRKNQD-LKMKVEMMSEAALNGNGE 1269
Cdd:pfam15921 704 AQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITA--KRGQIDaLQSKIQFLEEAMTNANKE 763
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
428-1074 |
2.50e-12 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 71.59 E-value: 2.50e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 428 NQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDL 507
Cdd:TIGR04523 47 NELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVEL 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 508 ALRAQEVAELRRRL-----ESSKPPGDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFG-AREEAFQKEIKALht 581
Cdd:TIGR04523 127 NKLEKQKKENKKNIdkfltEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDkIKNKLLKLELLLS-- 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 582 ATEKLSKENESLRSKLDHANKENsdvialwkSKLETAIASHQQAMEELKvsfskgigtdsAEFAELKTQIERLRLDYQHE 661
Cdd:TIGR04523 205 NLKKKIQKNKSLESQISELKKQN--------NQLKDNIEKKQQEINEKT-----------TEISNTQTQLNQLKDEQNKI 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 662 IESLQSKQdsersahaKEMETMQAKlmkiIKEKEDSLEAVKARLDSAEDQHlvemEDTLNKLQEAEIKanSITKELQEKE 741
Cdd:TIGR04523 266 KKQLSEKQ--------KELEQNNKK----IKELEKQLNQLKSEISDLNNQK----EQDWNKELKSELK--NQEKKLEEIQ 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 742 LVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKF 821
Cdd:TIGR04523 328 NQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLN 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 822 KEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQS 901
Cdd:TIGR04523 408 QQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQK 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 902 QQQAARKHEEEKKELEEKLLELEKKMETSYNQCQdLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRD-L 980
Cdd:TIGR04523 488 QKELKSKEKELKKLNEEKKELEEKVKDLTKKISS-LKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDeK 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 981 MQDMEELKTQADKAKAAQTAEDamQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVEN 1060
Cdd:TIGR04523 567 NKEIEELKQTQKSLKKKQEEKQ--ELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLK 644
|
650
....*....|....
gi 1907165170 1061 QKMEEFKKEIETLK 1074
Cdd:TIGR04523 645 QEVKQIKETIKEIR 658
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
863-1208 |
4.32e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 71.24 E-value: 4.32e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 863 LRLKERSvEELQLKLTKANENASFLQKSIGEV-----TL-----KAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYN 932
Cdd:TIGR02168 168 SKYKERR-KETERKLERTRENLDRLEDILNELerqlkSLerqaeKAERYKELKAELRELELALLVLRLEELREELEELQE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 933 QCQDLKAKYEKASSETKTKHEEILQNLQKMLADtEDKLKAAQEANRDLMQDMEELKTQadKAKAAQTAEDAMQIMEQMTK 1012
Cdd:TIGR02168 247 ELKEAEEELEELTAELQELEEKLEELRLEVSEL-EEEIEELQKELYALANEISRLEQQ--KQILRERLANLERQLEELEA 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1013 EKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENV 1092
Cdd:TIGR02168 324 QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1093 KLAEELGRTRDEVtshQKLEEERSVLNNQLLEMKKRESEFRKDA-DEEKASLQKSISLTSALLTEKDAELEKLRNEVTVL 1171
Cdd:TIGR02168 404 RLEARLERLEDRR---ERLQQEIEELLKKLEEAELKELQAELEElEEELEELQEELERLEEALEELREELEEAEQALDAA 480
|
330 340 350
....*....|....*....|....*....|....*..
gi 1907165170 1172 RGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKE 1208
Cdd:TIGR02168 481 ERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG 517
|
|
| NIP100 |
COG5244 |
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ... |
60-121 |
5.11e-12 |
|
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 227569 [Multi-domain] Cd Length: 669 Bit Score: 70.48 E-value: 5.11e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907165170 60 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRP 121
Cdd:COG5244 6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
566-1203 |
3.13e-11 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 68.14 E-value: 3.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 566 GAREEAFQKEIKALHTATEKLSKENESLRSKLDHANkENSDVIALWKSKLETAIASHQQAMEELkvsfskgigtdsaefA 645
Cdd:PRK02224 191 QLKAQIEEKEEKDLHERLNGLESELAELDEEIERYE-EQREQARETRDEADEVLEEHEERREEL---------------E 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 646 ELKTQIERLRLDyqheieslQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEavKARLDSAEDQHLVEMEDTLNKLQE 725
Cdd:PRK02224 255 TLEAEIEDLRET--------IAETEREREELAEEVRDLRERLEELEEERDDLLA--EAGLDDADAEAVEARREELEDRDE 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 726 AeikansitkelqekelvltgLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSS 805
Cdd:PRK02224 325 E--------------------LRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRRE 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 806 ELEKLRENLTDMEAKFkekDDREDQLVKAKEKLEndiaEIMKMSGDNSSQLTKMNDELRLKERSVEElqlkltkanenas 885
Cdd:PRK02224 385 EIEELEEEIEELRERF---GDAPVDLGNAEDFLE----ELREERDELREREAELEATLRTARERVEE------------- 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 886 flqksiGEVTLKA----EQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKT-----KHEEIL 956
Cdd:PRK02224 445 ------AEALLEAgkcpECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAedrieRLEERR 518
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 957 QNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQAD-KAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNEL 1035
Cdd:PRK02224 519 EDLEELIAERRETIEEKRERAEELRERAAELEAEAEeKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLL 598
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1036 DTLkENNLKTVEELN-KSKELLSVENQKMEefkkeietlkqaaaqksqQLSALQEENVKLAEELGRTRDEvTSHQKLEEE 1114
Cdd:PRK02224 599 AAI-ADAEDEIERLReKREALAELNDERRE------------------RLAEKRERKRELEAEFDEARIE-EAREDKERA 658
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1115 RSVLNNqlLEMKKRESEfrkdadEEKASLQKSIsltsALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLES--DK 1192
Cdd:PRK02224 659 EEYLEQ--VEEKLDELR------EERDDLQAEI----GAVENELEELEELRERREALENRVEALEALYDEAEELESmyGD 726
|
650
....*....|.
gi 1907165170 1193 VKLELKVKNLE 1203
Cdd:PRK02224 727 LRAELRQRNVE 737
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
351-997 |
3.62e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.04 E-value: 3.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 351 ALQEALKEKQqhIEQLLAERDLERAEVAKAtshvgeiEQELAlardghdqhvlELEAKMDQLRTMVEAADREKVELLNQL 430
Cdd:COG1196 217 ELKEELKELE--AELLLLKLRELEAELEEL-------EAELE-----------ELEAELEELEAELAELEAELEELRLEL 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 431 EEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALR 510
Cdd:COG1196 277 EELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 511 AQEVAELRRRLEsskppgdvdmslsllQEISALQEKLEAIHTDHQGEMTSLKEhfgarEEAFQKEIKALHTATEKLSKEN 590
Cdd:COG1196 357 EAELAEAEEALL---------------EAEAELAEAEEELEELAEELLEALRA-----AAELAAQLEELEEAEEALLERL 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 591 ESLRSKLDHANKEnsdvialwKSKLETAIASHQQAMEELKvsfskgigTDSAEFAELKTQIERLRLDYQHEIESLQSKQD 670
Cdd:COG1196 417 ERLEEELEELEEA--------LAELEEEEEEEEEALEEAA--------EEEAELEEEEEALLELLAELLEEAALLEAALA 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 671 SERSAHAKEmetmqaklmkiiKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDS 750
Cdd:COG1196 481 ELLEELAEA------------AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAL 548
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 751 LNQVNQVKETLEKELQTLKEKFASTSEEAVSaqtrmqdtvNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQ 830
Cdd:COG1196 549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPL---------DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 831 LVKAKEKLENDIAEIMKmsgdnssqltKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHE 910
Cdd:COG1196 620 DTLLGRTLVAARLEAAL----------RRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 911 EEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDkLKAAQEANRDLMQDMEELKTQ 990
Cdd:COG1196 690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL-LEEEALEELPEPPDLEELERE 768
|
....*..
gi 1907165170 991 ADKAKAA 997
Cdd:COG1196 769 LERLERE 775
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
573-1213 |
4.68e-11 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 67.44 E-value: 4.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 573 QKEIKALHTATEKLSKENESLRSKLDHANKENSDVIA------LWKSKLETAIAS----------HQQAMEELKVSFSKG 636
Cdd:pfam05483 112 RKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKennatrHLCNLLKETCARsaektkkyeyEREETRQVYMDLNNN 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 637 IGTDSAEFAELKTQIERLRLDYQHEIeslqsKQDSERSAHAKEmetmqaKLMKIIKEKEDSLEAVKARLDSAEDQhlveM 716
Cdd:pfam05483 192 IEKMILAFEELRVQAENARLEMHFKL-----KEDHEKIQHLEE------EYKKEINDKEKQVSLLLIQITEKENK----M 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 717 EDTLNKLQEAEIKANsitkELQEKelvlTGLQD-SLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQ 795
Cdd:pfam05483 257 KDLTFLLEESRDKAN----QLEEK----TKLQDeNLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQ 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 796 KEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAK----EKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVE 871
Cdd:pfam05483 329 LTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEqqrlEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELE 408
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 872 ELQLKL----TKANENASFlqKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEK---A 944
Cdd:pfam05483 409 ELKKILaedeKLLDEKKQF--EKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKeklK 486
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 945 SSETKTKHEEILQNLQKMLADTED---KLKAAQEANRDLMQDMEELKTQADKAKAAQTA-EDAMQIMEQMTKEKTETLAS 1020
Cdd:pfam05483 487 NIELTAHCDKLLLENKELTQEASDmtlELKKHQEDIINCKKQEERMLKQIENLEEKEMNlRDELESVREEFIQKGDEVKC 566
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1021 LEDTKQTNARLQNELDTLKENNLKTVE-ELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELG 1099
Cdd:pfam05483 567 KLDKSEENARSIEYEVLKKEKQMKILEnKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELA 646
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1100 RTRDE----VTSHQKLEEERSVLNNQLLEmkkrESEFRKDADEEKASLQKSISL-TSALLTEKDAELEKLRNEVTVLRGE 1174
Cdd:pfam05483 647 SAKQKfeeiIDNYQKEIEDKKISEEKLLE----EVEKAKAIADEAVKLQKEIDKrCQHKIAEMVALMEKHKHQYDKIIEE 722
|
650 660 670 680
....*....|....*....|....*....|....*....|
gi 1907165170 1175 NATAKSLH-SVVQTLESDKVKLELKVKNLELQLKENKRQL 1213
Cdd:pfam05483 723 RDSELGLYkNKEQEQSSAKAALEIELSNIKAELLSLKKQL 762
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
352-1169 |
5.95e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 67.30 E-value: 5.95e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 352 LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELE---AKMDQLRTMVEAADREKVELLN 428
Cdd:pfam02463 242 LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEelkSELLKLERRKVDDEEKLKESEK 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 429 QLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTK---ADKLQRELEDTRVATVSEKSRIMELEK 505
Cdd:pfam02463 322 EKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLeeeLLAKKKLESERLSSAAKLKEEELELKS 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 506 DLALRAQEVAELRRRLESSKppgdVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEK 585
Cdd:pfam02463 402 EEEKEAQLLLELARQLEDLL----KEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKET 477
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 586 LSKENESLRSKLDHANKENSDVIALwkSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESL 665
Cdd:pfam02463 478 QLVKLQEQLELLLSRQKLEERSQKE--SKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSA 555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 666 QSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKANSITKELQEKELVLT 745
Cdd:pfam02463 556 TADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELT 635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 746 GLQDSLNqvnqVKETLEKELQTLKEKFASTSEeavsAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKD 825
Cdd:pfam02463 636 KLKESAK----AKESGLRKGVSLEEGLAEKSE----VKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQR 707
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 826 dREDQLVKAKEKLENDIAEIMKMSGDNSSQltkmndelrlkERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQA 905
Cdd:pfam02463 708 -EKEELKKLKLEAEELLADRVQEAQDKINE-----------ELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKE 775
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 906 ARKHEEEKKELEEKLLELEKKMETSyNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDME 985
Cdd:pfam02463 776 LAEEREKTEKLKVEEEKEEKLKAQE-EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE 854
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 986 ELKTQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEE 1065
Cdd:pfam02463 855 ELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYE 934
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1066 FKKEIETLKQAAAQKSQQLSALQEENVKLAEElgrtrdevtshQKLEEERSVLNNQLLEMKKRESEFRKDadeekaslqk 1145
Cdd:pfam02463 935 EEPEELLLEEADEKEKEENNKEEEEERNKRLL-----------LAKEELGKVNLMAIEEFEEKEERYNKD---------- 993
|
810 820
....*....|....*....|....
gi 1907165170 1146 siSLTSALLTEKDAELEKLRNEVT 1169
Cdd:pfam02463 994 --ELEKERLEEEKKKLIRAIIEET 1015
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
807-1215 |
6.12e-11 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 67.01 E-value: 6.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 807 LEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSV----------EELQLK 876
Cdd:PRK03918 160 YENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELeklekevkelEELKEE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 877 LTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELE-KKMETSYNQCQDLKAKYEKASSE---TKTKH 952
Cdd:PRK03918 240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKElKEKAEEYIKLSEFYEEYLDELREiekRLSRL 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 953 EEILQNLQKMLADTEDK---LKAAQEANRDLMQDMEELKtqadkaKAAQTAEDAMQIMEQMTKEKTETlasledTKQTNA 1029
Cdd:PRK03918 320 EEEINGIEERIKELEEKeerLEELKKKLKELEKRLEELE------ERHELYEEAKAKKEELERLKKRL------TGLTPE 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1030 RLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEEN-----VKLAEELGRTRDE 1104
Cdd:PRK03918 388 KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkellEEYTAELKRIEKE 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1105 VtshQKLEEERSVLNNQLLEMKK---RESEF---RKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATA 1178
Cdd:PRK03918 468 L---KEIEEKERKLRKELRELEKvlkKESELiklKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSL 544
|
410 420 430
....*....|....*....|....*....|....*..
gi 1907165170 1179 KSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSS 1215
Cdd:PRK03918 545 KKELEKLEELKKKLAELEKKLDELEEELAELLKELEE 581
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
430-1289 |
6.26e-11 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 67.30 E-value: 6.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 430 LEEEKRKVEDLQFRVEEESITKGDLEtQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLAL 509
Cdd:pfam02463 166 RLKRKKKEALKKLIEETENLAELIID-LEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 510 RAQEVAELRrrlesskppgdvdmsLSLLQEISALQEKLEAIHTDHQGEMtslkehfgaREEAFQKEIKALHTATEKLSKE 589
Cdd:pfam02463 245 LLRDEQEEI---------------ESSKQEIEKEEEKLAQVLKENKEEE---------KEKKLQEEELKLLAKEEEELKS 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 590 NESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQ 669
Cdd:pfam02463 301 ELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKK 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 670 DSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARldsaedqhlvemedtlnklQEAEIKANSITKELQEKELVLTGLQD 749
Cdd:pfam02463 381 LESERLSSAAKLKEEELELKSEEEKEAQLLLELAR-------------------QLEDLLKEEKKEELEILEEEEESIEL 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 750 SLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRmQDTVNKLHQKEEqfnvlssELEKLRENLTDMEAKFKEKDDRED 829
Cdd:pfam02463 442 KQGKLTEEKEELEKQELKLLKDELELKKSEDLLKET-QLVKLQEQLELL-------LSRQKLEERSQKESKARSGLKVLL 513
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 830 QLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKH 909
Cdd:pfam02463 514 ALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKS 593
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 910 EEEKKELEEKLLELEKKMETSYNQCQ-DLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELK 988
Cdd:pfam02463 594 IAVLEIDPILNLAQLDKATLEADEDDkRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTK 673
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 989 TQADKAKAAQTAEDAMQIMEQmtKEKTETLASLEDTKQTNARLQNELDTLKENNLKTvEELNKSKELLSVENQKMEEFKK 1068
Cdd:pfam02463 674 ELLEIQELQEKAESELAKEEI--LRRQLEIKKKEQREKEELKKLKLEAEELLADRVQ-EAQDKINEELKLLKQKIDEEEE 750
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1069 EIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVtshqKLEEERSVLNNQLLEMKKRESEfRKDADEEKASLQKSIS 1148
Cdd:pfam02463 751 EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLK----VEEEKEEKLKAQEEELRALEEE-LKEEAELLEEEQLLIE 825
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1149 LTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDE 1228
Cdd:pfam02463 826 QEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEE 905
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907165170 1229 RAQESQIDFLNSVIvDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQSKKKPRL 1289
Cdd:pfam02463 906 SQKLNLLEEKENEI-EERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRL 965
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
679-1163 |
1.46e-10 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 65.81 E-value: 1.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 679 EMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhlveMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVK 758
Cdd:TIGR04523 222 ELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQ----LNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEI 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 759 ETLEKELQTLKEKfaSTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKL 838
Cdd:TIGR04523 298 SDLNNQKEQDWNK--ELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKL 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 839 ENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEvtLKAEQSQQQAARKheeekkelee 918
Cdd:TIGR04523 376 KKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIER--LKETIIKNNSEIK---------- 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 919 KLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEI---LQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAK 995
Cdd:TIGR04523 444 DLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIkqnLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLK 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 996 AAQTA-EDAMQIMEQMTKEKTETLASLEDTKQTNA------RLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKK 1068
Cdd:TIGR04523 524 EKIEKlESEKKEKESKISDLEDELNKDDFELKKENlekeidEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIK 603
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1069 EIETLKQAAAQKSQQLSALQEENVKLAEELgrtRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSIS 1148
Cdd:TIGR04523 604 EIEEKEKKISSLEKELEKAKKENEKLSSII---KNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIE 680
|
490
....*....|....*
gi 1907165170 1149 LTSALLTEKDAELEK 1163
Cdd:TIGR04523 681 LMKDWLKELSLHYKK 695
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
721-1216 |
1.76e-10 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 65.43 E-value: 1.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 721 NKLQEAEIKANSITKELQEKELVLTGLQDSL-------NQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKL 793
Cdd:TIGR04523 33 TEEKQLEKKLKTIKNELKNKEKELKNLDKNLnkdeekiNNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEI 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 794 HQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEEL 873
Cdd:TIGR04523 113 KNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKI 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 874 QLKLTKANENASFLQKSIGEV-TLKAEQSQQQAARKH-EEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTK 951
Cdd:TIGR04523 193 KNKLLKLELLLSNLKKKIQKNkSLESQISELKKQNNQlKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEK 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 952 HEEILQNLQKmLADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTAEDAMQIMEQMTKEKTetlaSLEDTKQTNARL 1031
Cdd:TIGR04523 273 QKELEQNNKK-IKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNK----IISQLNEQISQL 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1032 QNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETL--------------KQAAAQKSQQLSALQEENVKLAEE 1097
Cdd:TIGR04523 348 KKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLesqindleskiqnqEKLNQQKDEQIKKLQQEKELLEKE 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1098 LGRTRDEVTSHQK----LEEERSVLNNQLLEMKKRESEFRKDADEEKAS---LQKSISLTSALLTEKDAELEKLRNEVTV 1170
Cdd:TIGR04523 428 IERLKETIIKNNSeikdLTNQDSVKELIIKNLDNTRESLETQLKVLSRSinkIKQNLEQKQKELKSKEKELKKLNEEKKE 507
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1171 LRGENATAK----SLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSS 1216
Cdd:TIGR04523 508 LEEKVKDLTkkisSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKE 557
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
678-1236 |
1.96e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 65.73 E-value: 1.96e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 678 KEMETMQAKLMK---IIKEKEDSLE-----AVKAR----LDSAEDQHLVEMedTLNKLQEAEIKANSITKELQEKELVLT 745
Cdd:COG1196 179 RKLEATEENLERledILGELERQLEplerqAEKAEryreLKEELKELEAEL--LLLKLRELEAELEELEAELEELEAELE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 746 GLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKD 825
Cdd:COG1196 257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 826 DREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQA 905
Cdd:COG1196 337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 906 ARKHEEEKKELEEKLLELEKKMETsynqcqdlkAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDME 985
Cdd:COG1196 417 ERLEEELEELEEALAELEEEEEEE---------EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 986 ELKTQADKAKAAQTAED-------AMQIMEQMTK-------------------EKTETLASLEDTKQTNARLQNELDTLK 1039
Cdd:COG1196 488 EAAARLLLLLEAEADYEgflegvkAALLLAGLRGlagavavligveaayeaalEAALAAALQNIVVEDDEVAAAAIEYLK 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1040 ENNL--KTVEELNKSKELLSVENQKMEEFKKE----IETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEE 1113
Cdd:COG1196 568 AAKAgrATFLPLDKIRARAALAAALARGAIGAavdlVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1114 ERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKV 1193
Cdd:COG1196 648 EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALE 727
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 1907165170 1194 KLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQID 1236
Cdd:COG1196 728 EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
990-1263 |
2.42e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 65.34 E-value: 2.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 990 QADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKE 1069
Cdd:COG1196 238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1070 IETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVtshQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISL 1149
Cdd:COG1196 318 LEELEEELAELEEELEELEEELEELEEELEEAEEEL---EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1150 TSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDER 1229
Cdd:COG1196 395 AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474
|
250 260 270
....*....|....*....|....*....|....
gi 1907165170 1230 AQESQIDFLNSVIVDLQRKNQDLKMKVEMMSEAA 1263
Cdd:COG1196 475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
406-1229 |
1.35e-09 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 62.83 E-value: 1.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 406 EAKMDQLRTMVEAADREKVELLnqLEEEKRKVEDLQFRVEEESitkgdletqtKLEHARTKELEQSLLFEKTKADKLQRE 485
Cdd:pfam15921 58 EVELDSPRKIIAYPGKEHIERV--LEEYSHQVKDLQRRLNESN----------ELHEKQKFYLRQSVIDLQTKLQEMQME 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 486 ledtRVATVSEKSRIMELEKDLALRAQEVAElrrRLESSKppgdvDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHF 565
Cdd:pfam15921 126 ----RDAMADIRRRESQSQEDLRNQLQNTVH---ELEAAK-----CLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 566 GAREEAFQKEI-----------KALHTATEKLSKENESLRSKLdhankenSDVIALWKSKLETAIASHQQAMEELkvsfs 634
Cdd:pfam15921 194 VDFEEASGKKIyehdsmstmhfRSLGSAISKILRELDTEISYL-------KGRIFPVEDQLEALKSESQNKIELL----- 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 635 kgigtdsaeFAELKTQIERLRLDYQHEIESLQSKQDSERSahakEMETMQAKlMKIIKEKEDSLEAVKARldsaedqHLV 714
Cdd:pfam15921 262 ---------LQQHQDRIEQLISEHEVEITGLTEKASSARS----QANSIQSQ-LEIIQEQARNQNSMYMR-------QLS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 715 EMEDTLNKLQ----EAEIKANSITKELqEKELVL-----TGLQDSLNQVNQVKETLEKELQTL------KEKFASTSEEA 779
Cdd:pfam15921 321 DLESTVSQLRselrEAKRMYEDKIEEL-EKQLVLanselTEARTERDQFSQESGNLDDQLQKLladlhkREKELSLEKEQ 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 780 vsaQTRMQD-------TVNKLHQKEEQFNVlssELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDN 852
Cdd:pfam15921 400 ---NKRLWDrdtgnsiTIDHLRRELDDRNM---EVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLEST 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 853 SSQLTKMNDELRLKERSVEELQLklTKANENASFLQKsigEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYN 932
Cdd:pfam15921 474 KEMLRKVVEELTAKKMTLESSER--TVSDLTASLQEK---ERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQT 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 933 QCQDLKAKYEKASSETKTKHEEIlQNLQKML--------ADTEDKLKAAQEANrDLMQDMEELKTQADKAKAAQTAEDAM 1004
Cdd:pfam15921 549 ECEALKLQMAEKDKVIEILRQQI-ENMTQLVgqhgrtagAMQVEKAQLEKEIN-DRRLELQEFKILKDKKDAKIRELEAR 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1005 QIMEQMTKEK-----TETLASLEDTKQTNARLQNELDTLKE--NNLKTVEEL------NKSKELLSVENQ-KME------ 1064
Cdd:pfam15921 627 VSDLELEKVKlvnagSERLRAVKDIKQERDQLLNEVKTSRNelNSLSEDYEVlkrnfrNKSEEMETTTNKlKMQlksaqs 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1065 EFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNnqllemkkRESEFRKdadEEKASLQ 1144
Cdd:pfam15921 707 ELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNAN--------KEKHFLK---EEKNKLS 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1145 KSISLTSallTEKDaeleKLRNEVTVLRgenatakslhsvvqtleSDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQA 1224
Cdd:pfam15921 776 QELSTVA---TEKN----KMAGELEVLR-----------------SQERRLKEKVANMEVALDKASLQFAECQDIIQRQE 831
|
....*
gi 1907165170 1225 EEDER 1229
Cdd:pfam15921 832 QESVR 836
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
408-1093 |
1.65e-09 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 62.68 E-value: 1.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 408 KMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGD-LETQTKLEhartKELEQSLLFEKTKADKLQREL 486
Cdd:TIGR00618 174 PLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHErKQVLEKEL----KHLREALQQTQQSHAYLTQKR 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 487 EdtrvaTVSEKSRIMELEKDLALRAQEVAELRRRLESSKPPGDVDMSLSLLQEISA----LQEKLEAIHTDHQGEMTSLK 562
Cdd:TIGR00618 250 E-----AQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKavtqIEQQAQRIHTELQSKMRSRA 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 563 EHFGAREEAFQKE---------IKALHTATEKLSKENESLRSKLDHANKENSDV--IALWKSKLETAIASHQQAMEELKV 631
Cdd:TIGR00618 325 KLLMKRAAHVKQQssieeqrrlLQTLHSQEIHIRDAHEVATSIREISCQQHTLTqhIHTLQQQKTTLTQKLQSLCKELDI 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 632 --SFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQ--DSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDS 707
Cdd:TIGR00618 405 lqREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAaaITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQ 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 708 AEDQHLVEmEDTLNKLQEAEIKANSITKELQEKELV----------LTGLQDSLNQVNQVKETLEKELQTLKEKFASTSE 777
Cdd:TIGR00618 485 ETRKKAVV-LARLLELQEEPCPLCGSCIHPNPARQDidnpgpltrrMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKE 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 778 EAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLREnLTDMEAKFKEKDDREDQLVKAKEKLENDIAEImkmsgdnSSQLT 857
Cdd:TIGR00618 564 QMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQD-LTEKLSEAEDMLACEQHALLRKLQPEQDLQDV-------RLHLQ 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 858 KMNDELRLKERSVEELQLKLTKANENASFLQ--------KSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMET 929
Cdd:TIGR00618 636 QCSQELALKLTALHALQLTLTQERVREHALSirvlpkelLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEE 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 930 SYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEAN-RDLMQDMEELKTQADKAKAAQTAEDAMQIME 1008
Cdd:TIGR00618 716 YDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHfNNNEEVTAALQTGAELSHLAAEIQFFNRLRE 795
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1009 QMTKEKTETLASLE---DTKQTNARLQNELDTLKENNLKT-VEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQL 1084
Cdd:TIGR00618 796 EDTHLLKTLEAEIGqeiPSDEDILNLQCETLVQEEEQFLSrLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLS 875
|
....*....
gi 1907165170 1085 SALQEENVK 1093
Cdd:TIGR00618 876 DKLNGINQI 884
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
678-1173 |
2.06e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 62.39 E-value: 2.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 678 KEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhLVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQV 757
Cdd:PRK03918 196 KEKEKELEEVLREINEISSELPELREELEKLEKE-VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKE 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 758 KETLE---KELQTLKEKfastSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEakfkEKDDREDQLVKA 834
Cdd:PRK03918 275 IEELEekvKELKELKEK----AEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE----EKEERLEELKKK 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 835 KEKLENDIAEIMKMSGDNSSQLTKMNDELRLKER----SVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHE 910
Cdd:PRK03918 347 LKELEKRLEELEERHELYEEAKAKKEELERLKKRltglTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKK 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 911 EEKKELEEKLLELEKKMETSYNQCQDLKAKYE---KASSETKTKHEEILQNLQKMLADTEDKLKAAQE--ANRDLMQDME 985
Cdd:PRK03918 427 AIEELKKAKGKCPVCGRELTEEHRKELLEEYTaelKRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLK 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 986 ELKTQA---DKAKAAQTAEDAMQIMEQMTKEKTE------TLASLEDTKQTNARLQNELDTLKE---NNLKTVEELN-KS 1052
Cdd:PRK03918 507 ELEEKLkkyNLEELEKKAEEYEKLKEKLIKLKGEikslkkELEKLEELKKKLAELEKKLDELEEelaELLKELEELGfES 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1053 KELLSVENQKMEEFKKEIETLKQAAAQ---KSQQLSALQEENVKLAEELGRTRDEVTS---------------------- 1107
Cdd:PRK03918 587 VEELEERLKELEPFYNEYLELKDAEKElerEEKELKKLEEELDKAFEELAETEKRLEElrkeleelekkyseeeyeelre 666
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1108 -HQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKsisltsalLTEKDAELEKL---RNEVTVLRG 1173
Cdd:PRK03918 667 eYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE--------REKAKKELEKLekaLERVEELRE 728
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
623-1000 |
3.66e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 61.62 E-value: 3.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 623 QQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQHEIE--SLQS-KQDSERSAHAKEMETMqaklmkiikekEDSLE 699
Cdd:TIGR02169 173 EKALEELEE-VEENIERLDLIIDEKRQQLERLRREREKAERyqALLKeKREYEGYELLKEKEAL-----------ERQKE 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 700 AVKARLDSAEDqhlvEMEDtlnklqeaeikansITKELQEKELVLTGLQDSLNQVN-QVKETLEKELQTLKEKFASTSEE 778
Cdd:TIGR02169 241 AIERQLASLEE----ELEK--------------LTEEISELEKRLEEIEQLLEELNkKIKDLGEEEQLRVKEKIGELEAE 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 779 AVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLEndiaeimkmsgdnssqltk 858
Cdd:TIGR02169 303 IASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELK------------------- 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 859 mnDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELekkmetsyNQCQDLK 938
Cdd:TIGR02169 364 --EELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLN--------AAIAGIE 433
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907165170 939 AKYEKASSETKTKHEEI------LQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTA 1000
Cdd:TIGR02169 434 AKINELEEEKEDKALEIkkqewkLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARA 501
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
404-1212 |
3.88e-09 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 61.60 E-value: 3.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 404 ELEAKMDQLRTMVEAADREKVELlNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQ 483
Cdd:TIGR00606 225 QITSKEAQLESSREIVKSYENEL-DPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQL 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 484 RELEDTRVATVSEKSR-IMELEKDLALRAQEvaelRRRLESSKPPGDVDMSLSLLQEiSALQEKLEAIHTDHQGEMTSLK 562
Cdd:TIGR00606 304 NDLYHNHQRTVREKEReLVDCQRELEKLNKE----RRLLNQEKTELLVEQGRLQLQA-DRHQEHIRARDSLIQSLATRLE 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 563 EHFGAREEAFQKEIKALHTatekLSKENESLRSKLdhankensdvIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSA 642
Cdd:TIGR00606 379 LDGFERGPFSERQIKNFHT----LVIERQEDEAKT----------AAQLCADLQSKERLKQEQADEIRDEKKGLGRTIEL 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 643 EFAELKTQIERLRldyqHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLvEMEDTLNK 722
Cdd:TIGR00606 445 KKEILEKKQEELK----FVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKA-DLDRKLRK 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 723 LQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEeavsaqtrMQDTvnkLHQKEEQFNV 802
Cdd:TIGR00606 520 LDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQ--------LEDW---LHSKSKEINQ 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 803 LSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKmSGDNSSQLTKMNDELrlkERSVEELQLKLTKANE 882
Cdd:TIGR00606 589 TRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCG-SQDEESDLERLKEEI---EKSSKQRAMLAGATAV 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 883 NASFLQKSIGEVT---------LKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHE 953
Cdd:TIGR00606 665 YSQFITQLTDENQsccpvcqrvFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEK 744
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 954 EILQNLQKMLADTEDklkaAQEANRDLMQDMEELKTQADKAKAAQTAEDAMQIMEQMTKEktetlasLEDTKQTNARLQN 1033
Cdd:TIGR00606 745 EIPELRNKLQKVNRD----IQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQME-------LKDVERKIAQQAA 813
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1034 ELDTLkeNNLKTVEELNKSKEllsVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEE 1113
Cdd:TIGR00606 814 KLQGS--DLDRTVQQVNQEKQ---EKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEE 888
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1114 ERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGE----NATAKSLHSVVQTLE 1189
Cdd:TIGR00606 889 QLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKvkniHGYMKDIENKIQDGK 968
|
810 820
....*....|....*....|....
gi 1907165170 1190 SD-KVKLELKVKNLELQLKENKRQ 1212
Cdd:TIGR00606 969 DDyLKQKETELNTVNAQLEECEKH 992
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
965-1270 |
8.30e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 60.34 E-value: 8.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 965 DTEDKLKAAQEaN----RDLMQD----MEELKTQADKAKAAQTAEDAMQI---------MEQMTKEKTETLASLEDTKQT 1027
Cdd:COG1196 176 EAERKLEATEE-NlerlEDILGElerqLEPLERQAEKAERYRELKEELKEleaellllkLRELEAELEELEAELEELEAE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1028 NARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETL----------KQAAAQKSQQLSA-LQEENVKLAE 1096
Cdd:COG1196 255 LEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLeqdiarleerRRELEERLEELEEeLAELEEELEE 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1097 ELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENA 1176
Cdd:COG1196 335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1177 TAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSgNTDAQAEEDERAQESQIDFLNSVIVDLQRKNQDLKMKV 1256
Cdd:COG1196 415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE-EEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493
|
330
....*....|....
gi 1907165170 1257 EMMSEAALNGNGED 1270
Cdd:COG1196 494 LLLLEAEADYEGFL 507
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
360-1149 |
9.92e-09 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 60.13 E-value: 9.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 360 QQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDghdQHVLELEAKMDQLR----TMVEAADRE---KVELLNQLEE 432
Cdd:pfam15921 73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLR---QSVIDLQTKLQEMQmerdAMADIRRREsqsQEDLRNQLQN 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 433 EKRKVED---LQFRVEEESITKGDLETQTKLEHARTKELEQSLL--FEKTKADKLQrelEDTRVATV------SEKSRIM 501
Cdd:pfam15921 150 TVHELEAakcLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILvdFEEASGKKIY---EHDSMSTMhfrslgSAISKIL 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 502 -ELEKDLALRAQEVAELRRRLESSKPPGDVDMSLSLLQEisalQEKLEAIHTDHQGEMTSLKEhfgaREEAFQKEIKALH 580
Cdd:pfam15921 227 rELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQH----QDRIEQLISEHEVEITGLTE----KASSARSQANSIQ 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 581 TATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKvsfsKGIGTDSAEFAELKTQierlRLDYQH 660
Cdd:pfam15921 299 SQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELE----KQLVLANSELTEARTE----RDQFSQ 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 661 EIESLQSkqdsersahakEMETMQAKLMKiiKEKEDSLEAVKARL-------DSAEDQHLV-EMEDTLNKLQEAEIKANS 732
Cdd:pfam15921 371 ESGNLDD-----------QLQKLLADLHK--REKELSLEKEQNKRlwdrdtgNSITIDHLRrELDDRNMEVQRLEALLKA 437
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 733 ITKELQ---EKELV-LTGLQDSLNQVNQVKETLEKELQTLK---EKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSS 805
Cdd:pfam15921 438 MKSECQgqmERQMAaIQGKNESLEKVSSLTAQLESTKEMLRkvvEELTAKKMTLESSERTVSDLTASLQEKERAIEATNA 517
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 806 ELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLE---------NDIAEIMKMSGDNSSQLT-------------KMNDEL 863
Cdd:pfam15921 518 EITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEalklqmaekDKVIEILRQQIENMTQLVgqhgrtagamqveKAQLEK 597
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 864 RLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQ-QAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYE 942
Cdd:pfam15921 598 EINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLvNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE 677
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 943 KASSETKTKHEEILQNLQKMladtEDKLKAAQ---EANRDLMQDMEELKTQADKAkaaqtaedAMQIMEQMTKEKTETLA 1019
Cdd:pfam15921 678 VLKRNFRNKSEEMETTTNKL----KMQLKSAQselEQTRNTLKSMEGSDGHAMKV--------AMGMQKQITAKRGQIDA 745
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1020 sledtkqtnarLQNELDTLKEnnlkTVEELNKSKELLSVENQKMeefkkeietlkqaaaqkSQQLSALQEENVKLAEELG 1099
Cdd:pfam15921 746 -----------LQSKIQFLEE----AMTNANKEKHFLKEEKNKL-----------------SQELSTVATEKNKMAGELE 793
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1100 RTRDEvtsHQKLEEErsvLNNQLLEMKKRESEFRKDADEEKASLQKSISL 1149
Cdd:pfam15921 794 VLRSQ---ERRLKEK---VANMEVALDKASLQFAECQDIIQRQEQESVRL 837
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
334-1071 |
1.44e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 59.35 E-value: 1.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 334 LLTETSSRYARKISGTTALQEALKEKQQHIEQLLaERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDqlr 413
Cdd:pfam05483 159 LLKETCARSAEKTKKYEYEREETRQVYMDLNNNI-EKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKE--- 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 414 tmVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQsllfektKADKLQRELEDTRVAT 493
Cdd:pfam05483 235 --INDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIE-------KKDHLTKELEDIKMSL 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 494 VSEKSRIMELEKDLALRAQEVAELRRRLESSkppgdvdmslslLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQ 573
Cdd:pfam05483 306 QRSMSTQKALEEDLQIATKTICQLTEEKEAQ------------MEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLE 373
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 574 KEIKALHTATEKLSKENESLRSKLDHANKENSDVialwkSKLETAIASHQQAMEELKvsfskgigtdsaefaELKTQIER 653
Cdd:pfam05483 374 KNEDQLKIITMELQKKSSELEEMTKFKNNKEVEL-----EELKKILAEDEKLLDEKK---------------QFEKIAEE 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 654 LRLDYQHEIESLQSKQdsersahaKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhlvemedtlnKLQEAEIKANSI 733
Cdd:pfam05483 434 LKGKEQELIFLLQARE--------KEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKE----------KLKNIELTAHCD 495
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 734 TKELQEKELVltglQDSLNQVNQVKETLEKELQTLKEkfastseeavsaQTRMQDTVNKLHQKEEQfnvLSSELEKLREN 813
Cdd:pfam05483 496 KLLLENKELT----QEASDMTLELKKHQEDIINCKKQ------------EERMLKQIENLEEKEMN---LRDELESVREE 556
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 814 LTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKmndELRLKERSVEELQlkltkaNENASFLQKSige 893
Cdd:pfam05483 557 FIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKK---QIENKNKNIEELH------QENKALKKKG--- 624
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 894 vtlKAEQSQQQAarkheeekkeLEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAA 973
Cdd:pfam05483 625 ---SAENKQLNA----------YEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQ 691
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 974 QEANRDLMQDMEELKTQADKAKaaqtaedamQIMEQMTKEKTETLASLEDTKQTNARLQNELDTlKENNLKTveELNKSK 1053
Cdd:pfam05483 692 KEIDKRCQHKIAEMVALMEKHK---------HQYDKIIEERDSELGLYKNKEQEQSSAKAALEI-ELSNIKA--ELLSLK 759
|
730
....*....|....*...
gi 1907165170 1054 ELLSVENQKMEEFKKEIE 1071
Cdd:pfam05483 760 KQLEIEKEEKEKLKMEAK 777
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
402-1041 |
2.04e-08 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 59.08 E-value: 2.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 402 VLELEAKMDQLRTMVEA--ADREKVELLNQLEEEK--RKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKT 477
Cdd:pfam12128 188 MHSKEGKFRDVKSMIVAilEDDGVVPPKSRLNRQQveHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGY 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 478 KADKLQRELEDTRVATVSE--KSRIMELEKDLAlraQEVAELRRRLESSKppgdvdmslsllQEISALQEKLEAIHTDH- 554
Cdd:pfam12128 268 KSDETLIASRQEERQETSAelNQLLRTLDDQWK---EKRDELNGELSAAD------------AAVAKDRSELEALEDQHg 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 555 ---QGEMTSLKEH------FGAREEAFQKEIKALHTATEKLSKENESLRSKLDhanKENSDVIALWKSKLE--------- 616
Cdd:pfam12128 333 aflDADIETAAADqeqlpsWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK---EQNNRDIAGIKDKLAkireardrq 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 617 -TAIASHQQAME-ELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAhaKEMETMQAKLMKIIKEK 694
Cdd:pfam12128 410 lAVAEDDLQALEsELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFD--ERIERAREEQEAANAEV 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 695 EDsLEAVKARLDSAEDQHLVemedtlnKLQEAEIKANSITKELQEKELVLTGLQDSL-----NQVNQVKETLEK------ 763
Cdd:pfam12128 488 ER-LQSELRQARKRRDQASE-------ALRQASRRLEERQSALDELELQLFPQAGTLlhflrKEAPDWEQSIGKvispel 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 764 --------------------------ELQTLKEKFASTSEEAV-----SAQTRMQDTVNKLHQKEEQFNVLSSELEKLRE 812
Cdd:pfam12128 560 lhrtdldpevwdgsvggelnlygvklDLKRIDVPEWAASEEELrerldKAEEALQSAREKQAAAEEQLVQANGELEKASR 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 813 NLTDMEAKFKEKDDREDQLVKAKE----KLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQ--LKLTKANENASF 886
Cdd:pfam12128 640 EETFARTALKNARLDLRRLFDEKQsekdKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQkeQKREARTEKQAY 719
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 887 LQKSIG----------------EVTLKAEQSQQQAARKHEEEKK----ELEEKLLELEKKMETSYNQCQDLKAK------ 940
Cdd:pfam12128 720 WQVVEGaldaqlallkaaiaarRSGAKAELKALETWYKRDLASLgvdpDVIAKLKREIRTLERKIERIAVRRQEvlryfd 799
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 941 ------------YEKASSETKTKHEEILQNLQKMLADTEDKLKAAQ---EANRDLMQDMEELKTQAD--KAKAAQTAEDA 1003
Cdd:pfam12128 800 wyqetwlqrrprLATQLSNIERAISELQQQLARLIADTKLRRAKLEmerKASEKQQVRLSENLRGLRceMSKLATLKEDA 879
|
730 740 750
....*....|....*....|....*....|....*...
gi 1907165170 1004 MQimEQMTKEKTETLASLEDTKQTNARLQNELDTLKEN 1041
Cdd:pfam12128 880 NS--EQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEH 915
|
|
| CLIP1_ZNF |
pfam16641 |
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ... |
1328-1344 |
9.84e-08 |
|
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.
Pssm-ID: 465212 Cd Length: 17 Bit Score: 49.00 E-value: 9.84e-08
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
334-1234 |
1.42e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 56.34 E-value: 1.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 334 LLTETSSRYARKISGTTALQEALKEKQQHIEQLlaERDLERAEVAKATSHVGEIEQELALARdgHDQHVLELEAKMDQLR 413
Cdd:pfam01576 76 ILHELESRLEEEEERSQQLQNEKKKMQQHIQDL--EEQLDEEEAARQKLQLEKVTTEAKIKK--LEEDILLLEDQNSKLS 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 414 TMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELeqsllfEKTKAdKLQRELEDTRVAT 493
Cdd:pfam01576 152 KERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQEL------EKAKR-KLEGESTDLQEQI 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 494 VSEKSRIMELEKDLALRAQEVAELRRRLE-SSKPPGDVDMSLSLLQ-EISALQEKLEAiHTDHQGEMTSLKEHFGAREEA 571
Cdd:pfam01576 225 AELQAQIAELRAQLAKKEEELQAALARLEeETAQKNNALKKIRELEaQISELQEDLES-ERAARNKAEKQRRDLGEELEA 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 572 FQKEIKALHTAT-------EKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELK---VSFSKGIGTDS 641
Cdd:pfam01576 304 LKTELEDTLDTTaaqqelrSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKrnkANLEKAKQALE 383
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 642 AEFAELKTQIERL---RLDYQHEIESLQSkQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHL----- 713
Cdd:pfam01576 384 SENAELQAELRTLqqaKQDSEHKRKKLEG-QLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIklskd 462
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 714 -----VEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLK----------EKFASTSEE 778
Cdd:pfam01576 463 vssleSQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQaqlsdmkkklEEDAGTLEA 542
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 779 AVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTK 858
Cdd:pfam01576 543 LEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAE 622
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 859 MNDELRLKERSVEELQLKLTKANENASFLQKSIGEVT--LKAEQSQQQAArkheeekkeleekllelekkmetsynqcQD 936
Cdd:pfam01576 623 ERDRAEAEAREKETRALSLARALEEALEAKEELERTNkqLRAEMEDLVSS----------------------------KD 674
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 937 LKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTaEDAMQIMEQMTKEKTE 1016
Cdd:pfam01576 675 DVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARD-EQGEEKRRQLVKQVRE 753
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1017 TLASLEDTKQTNA-------RLQNELDTLKENnlktVEELNKSKE----LLSVENQKMEEFKKEIETLKQA-------AA 1078
Cdd:pfam01576 754 LEAELEDERKQRAqavaakkKLELDLKELEAQ----IDAANKGREeavkQLKKLQAQMKDLQRELEEARASrdeilaqSK 829
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1079 QKSQQLSALQEENVKLAEELG---RTRDEV-TSHQKLEEE--RSVLNNQLLEMKKRESEFR-KDADEEKASLQKSISLTS 1151
Cdd:pfam01576 830 ESEKKLKNLEAELLQLQEDLAaseRARRQAqQERDELADEiaSGASGKSALQDEKRRLEARiAQLEEELEEEQSNTELLN 909
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1152 ALLTEKDAELEKLRNEvtvLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEE--DER 1229
Cdd:pfam01576 910 DRLRKSTLQVEQLTTE---LAAERSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQLEEqlEQE 986
|
....*
gi 1907165170 1230 AQESQ 1234
Cdd:pfam01576 987 SRERQ 991
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
331-795 |
2.22e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.84 E-value: 2.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 331 RTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKAtshvgeieqelalardghDQHVLELEAKMD 410
Cdd:TIGR02169 651 KSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI------------------ENRLDELSQELS 712
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 411 QLRTMVEAADREKVELLNQLEEEKRKVEDLQfrveeesitkgdletqtklehARTKELEQSLLFEKTKADKLQRELEdtr 490
Cdd:TIGR02169 713 DASRKIGEIEKEIEQLEQEEEKLKERLEELE---------------------EDLSSLEQEIENVKSELKELEARIE--- 768
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 491 vatvseksrimELEKDLALRAQEVAELRRRLESSKppgdvdmslslLQEISALQEKLEAIHTDhqgemtslkehfgaree 570
Cdd:TIGR02169 769 -----------ELEEDLHKLEEALNDLEARLSHSR-----------IPEIQAELSKLEEEVSR----------------- 809
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 571 aFQKEIKALHTATEKLSKENESLRSKLDHANKENSDvialwkskLETAIASHQQAMEELKvsfskgigtdsAEFAELKTQ 650
Cdd:TIGR02169 810 -IEARLREIEQKLNRLTLEKEYLEKEIQELQEQRID--------LKEQIKSIEKEIENLN-----------GKKEELEEE 869
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 651 IERLRL---DYQHEIESLQSKQDsERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQhLVEMEDTLNKLQE-- 725
Cdd:TIGR02169 870 LEELEAalrDLESRLGDLKKERD-ELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE-LSEIEDPKGEDEEip 947
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907165170 726 -AEIKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQ 795
Cdd:TIGR02169 948 eEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
680-1128 |
2.35e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.16 E-value: 2.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 680 METMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLnklqeaeikansitKELQEKELVLTGLQDSLNQVNQVKE 759
Cdd:COG4717 40 LAFIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEEL--------------KEAEEKEEEYAELQEELEELEEELE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 760 TLEKELQTLKEKFastseEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLE 839
Cdd:COG4717 106 ELEAELEELREEL-----EKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 840 ndiAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEK 919
Cdd:COG4717 181 ---ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAA 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 920 LLELEKKMETSYNQCQDL-------------------KAKYEKASSETKTKHEEILQNLQKM-----LADTEDKLKAAQE 975
Cdd:COG4717 258 LLALLGLGGSLLSLILTIagvlflvlgllallflllaREKASLGKEAEELQALPALEELEEEeleelLAALGLPPDLSPE 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 976 ANRDLMQDMEELKTQADKAKAAQTAEDAMQIMEQMTK-------EKTETLASLEDTKQTNARLQNELDTLKENnlktVEE 1048
Cdd:COG4717 338 ELLELLDRIEELQELLREAEELEEELQLEELEQEIAAllaeagvEDEEELRAALEQAEEYQELKEELEELEEQ----LEE 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1049 LNKSKELLSVENQKmEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEvTSHQKLEEERSVLNNQLLEMKKR 1128
Cdd:COG4717 414 LLGELEELLEALDE-EELEEELEELEEELEELEEELEELREELAELEAELEQLEED-GELAELLQELEELKAELRELAEE 491
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
464-1076 |
3.06e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 55.07 E-value: 3.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 464 RTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKppgdvdmslsllQEISAL 543
Cdd:PRK03918 176 RRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELK------------EEIEEL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 544 QEKLEAIhtdhQGEMTSLKEHFGARE---EAFQKEIKALH------TATEKLSKENESLRSKLDHANKENSDvIALWKSK 614
Cdd:PRK03918 244 EKELESL----EGSKRKLEEKIRELEeriEELKKEIEELEekvkelKELKEKAEEYIKLSEFYEEYLDELRE-IEKRLSR 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 615 LETAIASHQQAMEELKvSFSKGIGTDSAEFAELKTQIERLRLDYQhEIESLQSKQDSERSAHAK----EMETMQAKLMKI 690
Cdd:PRK03918 319 LEEEINGIEERIKELE-EKEERLEELKKKLKELEKRLEELEERHE-LYEEAKAKKEELERLKKRltglTPEKLEKELEEL 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 691 IKEK---EDSLEAVKARLDSAEdQHLVEMEDTLNKLQEAEIKANSITKELQEKElvltgLQDSLNQVNQVKETLEKELQT 767
Cdd:PRK03918 397 EKAKeeiEEEISKITARIGELK-KEIKELKKAIEELKKAKGKCPVCGRELTEEH-----RKELLEEYTAELKRIEKELKE 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 768 LKEKFASTSEEAVSAQTRM--QDTVNKLHQKEEQFNVLSSELEKLreNLTDMEAKFKEKDDREDQLVKAKEKLENDIAEI 845
Cdd:PRK03918 471 IEEKERKLRKELRELEKVLkkESELIKLKELAEQLKELEEKLKKY--NLEELEKKAEEYEKLKEKLIKLKGEIKSLKKEL 548
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 846 MKMSGDNSSqLTKMNDELRLKERSVEELQLKLtkanENASFlqKSIGEVTLKaeqsqqqaarkheeekkeleekllelek 925
Cdd:PRK03918 549 EKLEELKKK-LAELEKKLDELEEELAELLKEL----EELGF--ESVEELEER---------------------------- 593
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 926 kmetsynqCQDLKAKYEKASSETKTKHEeiLQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTAEDAMQ 1005
Cdd:PRK03918 594 --------LKELEPFYNEYLELKDAEKE--LEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEE 663
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907165170 1006 IMEQMTKEKTETlasledtkqtnARLQNELDTLKennlKTVEELNKSKELLSVENQKMEEFKKEIETLKQA 1076
Cdd:PRK03918 664 LREEYLELSREL-----------AGLRAELEELE----KRREEIKKTLEKLKEELEEREKAKKELEKLEKA 719
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
351-846 |
6.47e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.15 E-value: 6.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 351 ALQEALKEKQQHIEqllAERDLERAEVAKATSHVGEIEQELALAR---DGHDQHVLELEAKMDQLRTMVEAADREKVELL 427
Cdd:COG4913 253 LLEPIRELAERYAA---ARERLAELEYLRAALRLWFAQRRLELLEaelEELRAELARLEAELERLEARLDALREELDELE 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 428 NQLEEEK-RKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRimeLEKD 506
Cdd:COG4913 330 AQIRGNGgDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEA---LEEA 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 507 LALRAQEVAELRRRLEsskppgdvdmslSLLQEISALQEKLEAIHTDHQGEMTSLKEHFG----------------AREE 570
Cdd:COG4913 407 LAEAEAALRDLRRELR------------ELEAEIASLERRKSNIPARLLALRDALAEALGldeaelpfvgelievrPEEE 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 571 AFQKEI-KALHT--------------ATEKLskENESLRSKLDhankenSDVIALWKSKLETAIASHQQAMEELKVSfsk 635
Cdd:COG4913 475 RWRGAIeRVLGGfaltllvppehyaaALRWV--NRLHLRGRLV------YERVRTGLPDPERPRLDPDSLAGKLDFK--- 543
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 636 gigtDSAEFAELKTQIERlRLDYQ--HEIESL-----------QSKQDSERSAHAKEMETMQ------------AKLMKI 690
Cdd:COG4913 544 ----PHPFRAWLEAELGR-RFDYVcvDSPEELrrhpraitragQVKGNGTRHEKDDRRRIRSryvlgfdnraklAALEAE 618
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 691 IKEKEDSLEAVKARLDSAEDQH--LVEMEDTLNKLQE---AEIKANSITKELQEKELVLTGLQDSLNQVnqvkETLEKEL 765
Cdd:COG4913 619 LAELEEELAEAEERLEALEAELdaLQERREALQRLAEyswDEIDVASAEREIAELEAELERLDASSDDL----AALEEQL 694
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 766 QTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLREN-----LTDMEAKFKEKDDRE------------ 828
Cdd:COG4913 695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLarlelRALLEERFAAALGDAverelrenleer 774
|
570
....*....|....*....
gi 1907165170 829 -DQLVKAKEKLENDIAEIM 846
Cdd:COG4913 775 iDALRARLNRAEEELERAM 793
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
335-594 |
6.69e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.15 E-value: 6.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 335 LTETSSRYARKISGTTALQEALKEKQQHIEQLlAERDLERAEVAKATSHVGEIEQELALARDGHDQhVLELEAKMDQLRT 414
Cdd:COG4913 622 LEEELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVASAEREIAELEAELERLDASSDD-LAALEEQLEELEA 699
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 415 MVEAADREKVELLNQLEEEKRKVEDLQFRVEeesitkgdlETQTKLEHA-RTKELEQSLLFEKtkadKLQRELEDTRVAT 493
Cdd:COG4913 700 ELEELEEELDELKGEIGRLEKELEQAEEELD---------ELQDRLEAAeDLARLELRALLEE----RFAAALGDAVERE 766
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 494 VSEK--SRIMELEKDLALRAQEVAELRRRLESSKPPGDVDMSLSL--LQEISALQEKLEAIH-TDHQGEMTSLKEHFGAR 568
Cdd:COG4913 767 LRENleERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLesLPEYLALLDRLEEDGlPEYEERFKELLNENSIE 846
|
250 260
....*....|....*....|....*...
gi 1907165170 569 E-EAFQKEIK-ALHTATEKLSKENESLR 594
Cdd:COG4913 847 FvADLLSKLRrAIREIKERIDPLNDSLK 874
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
480-1167 |
7.80e-07 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 53.67 E-value: 7.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 480 DKLQRELEDTRVATVSEKSRIM-----ELEKDLALRAQEVAELRRRLESSKPPGDVDMSLSLlqEISALQEKLEA----- 549
Cdd:pfam10174 13 ELLRRELDIKESKLGSSMNSIKtfwspELKKERALRKEEAARISVLKEQYRVTQEENQHLQL--TIQALQDELRAqrdln 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 550 --IHTDHQGEMTSLKEHFGAREEAfQKEIKALHTATEKLSKENESLRSKLDHANKEnsdvIALWKSKLETAIASHQQAME 627
Cdd:pfam10174 91 qlLQQDFTTSPVDGEDKFSTPELT-EENFRRLQSEHERQAKELFLLRKTLEEMELR----IETQKQTLGARDESIKKLLE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 628 ELKvsfSKGIGTDSAEF---------------AELKTQIERLRLDYQHEIESLQSK-QDSERSAHAKEMET-MQAKLMKI 690
Cdd:pfam10174 166 MLQ---SKGLPKKSGEEdwertrriaeaemqlGHLEVLLDQKEKENIHLREELHRRnQLQPDPAKTKALQTvIEMKDTKI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 691 ------IKEKEDSLEAVKARLDSAEDQH---LVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVKETL 761
Cdd:pfam10174 243 sslernIRDLEDEVQMLKTNGLLHTEDReeeIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNSDC 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 762 EKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLREnltDMEAKFKEKDDREDQLVKAKEK---L 838
Cdd:pfam10174 323 KQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTE---EKSTLAGEIRDLKDMLDVKERKinvL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 839 ENDIAEIMKMSGDNSSQLTKmndelrLKERsVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARkheeekkelee 918
Cdd:pfam10174 400 QKKIENLQEQLRDKDKQLAG------LKER-VKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQRER----------- 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 919 KLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEIL------QNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQAD 992
Cdd:pfam10174 462 EDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIdlkehaSSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLK 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 993 KAkaaQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENnLKTVEELNKSKEllsvenQKMEEFKKEIET 1072
Cdd:pfam10174 542 KA---HNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGI-LREVENEKNDKD------KKIAELESLTLR 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1073 LKQAAAQKSQQLSALQEENVKLAEELgrtrDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLqksiSLTSA 1152
Cdd:pfam10174 612 QMKEQNKKVANIKHGQQEMKKKGAQL----LEEARRREDNLADNSQQLQLEELMGALEKTRQELDATKARL----SSTQQ 683
|
730
....*....|....*
gi 1907165170 1153 LLTEKDAELEKLRNE 1167
Cdd:pfam10174 684 SLAEKDGHLTNLRAE 698
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
747-1002 |
8.01e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.84 E-value: 8.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 747 LQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDD 826
Cdd:COG4942 25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 827 REDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMndeLRLKERSVEELQLKLTKanenasfLQKSIGEVTLKAEQSQQQAA 906
Cdd:COG4942 105 ELAELLRALYRLGRQPPLALLLSPEDFLDAVRR---LQYLKYLAPARREQAEE-------LRADLAELAALRAELEAERA 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 907 RKheeekkeleekllelekkmETSYNQCQDLKAKYEKAssetKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEE 986
Cdd:COG4942 175 EL-------------------EALLAELEEERAALEAL----KAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
|
250
....*....|....*.
gi 1907165170 987 LKTQADKAKAAQTAED 1002
Cdd:COG4942 232 LEAEAAAAAERTPAAG 247
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
838-1226 |
1.09e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.53 E-value: 1.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 838 LENDIAEIMKMSGdnsSQLTKMNDELRlkerSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELE 917
Cdd:TIGR02169 140 LQGDVTDFISMSP---VERRKIIDEIA----GVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 918 ekllelekkmetsYNQCQDLKAKYE-KASSETKTKHEEILQNLQKMLADTE---DKLKAAQEANRDLMQDMEELKTQADK 993
Cdd:TIGR02169 213 -------------YQALLKEKREYEgYELLKEKEALERQKEAIERQLASLEeelEKLTEEISELEKRLEEIEQLLEELNK 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 994 AKAAQTAEDAMQIMEQMTkektETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETL 1073
Cdd:TIGR02169 280 KIKDLGEEEQLRVKEKIG----ELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKL 355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1074 KQAAAQKSQQLSAL----QEENVKLAEELGRTRDEVTSHQKLEEERSVLN---NQLLEMKKRESEFRKDADEEKASLQKS 1146
Cdd:TIGR02169 356 TEEYAELKEELEDLraelEEVDKEFAETRDELKDYREKLEKLKREINELKrelDRLQEELQRLSEELADLNAAIAGIEAK 435
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1147 ISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTlESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEE 1226
Cdd:TIGR02169 436 INELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKE-EYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEE 514
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
344-629 |
1.42e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.14 E-value: 1.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 344 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAkatshvgEIEQELALARDGHDQHVLELEAKMDQLRTMVEAA---- 419
Cdd:TIGR02168 726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELE-------AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLkeel 798
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 420 ---DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLF-------EKTKADKLQRELEDT 489
Cdd:TIGR02168 799 kalREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESlaaeieeLEELIEELESELEAL 878
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 490 RVATVSEKSRIMELEKDLALRAQEVAELRRRL--------ESSKPPGDVDMSLS-LLQEISALQEKLEAIHTDHQGEMTS 560
Cdd:TIGR02168 879 LNERASLEEALALLRSELEELSEELRELESKRselrreleELREKLAQLELRLEgLEVRIDNLQERLSEEYSLTLEEAEA 958
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907165170 561 LKEHFGAREEAFQKEIKALHTATEKLSKEN-------ESLRSKLDHANKENSDvialwkskLETAIASHQQAMEEL 629
Cdd:TIGR02168 959 LENKIEDDEEEARRRLKRLENKIKELGPVNlaaieeyEELKERYDFLTAQKED--------LTEAKETLEEAIEEI 1026
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
578-1202 |
1.46e-06 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 53.13 E-value: 1.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 578 ALHTATEKLSKENESLRSKldHANKENSDVIalwkSKLETAIASHQQAMEELKV-SFSKGIGTDSAEFAE----LKTQIE 652
Cdd:TIGR01612 1048 AIHTSIYNIIDEIEKEIGK--NIELLNKEIL----EEAEINITNFNEIKEKLKHyNFDDFGKEENIKYADeinkIKDDIK 1121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 653 RLRLDYQHEIESLQS-KQDSERsaHAKEMETMQAKLMKI---------IKEKEDSLEAVKARLDSAEDQHlVEMEDTLNK 722
Cdd:TIGR01612 1122 NLDQKIDHHIKALEEiKKKSEN--YIDEIKAQINDLEDVadkaisnddPEEIEKKIENIVTKIDKKKNIY-DEIKKLLNE 1198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 723 LQEAE--------IKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQ-----DT 789
Cdd:TIGR01612 1199 IAEIEkdktsleeVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDikaemET 1278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 790 VNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGD---------NSSQLTKMN 860
Cdd:TIGR01612 1279 FNISHDDDKDHHIISKKHDENISDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDinlylneiaNIYNILKLN 1358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 861 ------DELRLKERSVEELQLKLTKANENASFLQKSIGE-VTLKAEQSQQQAA--RKHEEEKKELEEKLLELEKKMETSY 931
Cdd:TIGR01612 1359 kikkiiDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDdINLEECKSKIESTldDKDIDECIKKIKELKNHILSEESNI 1438
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 932 NqcqdlkaKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQE-ANRDLMQDMEELKTQADKAKAAQTAEDA------- 1003
Cdd:TIGR01612 1439 D-------TYFKNADENNENVLLLFKNIEMADNKSQHILKIKKDnATNDHDFNINELKEHIDKSKGCKDEADKnakaiek 1511
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1004 -MQIMEQMTKEKTETLasledTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVE----NQKMEEFKKEIETLKQAAA 1078
Cdd:TIGR01612 1512 nKELFEQYKKDVTELL-----NKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEaeksEQKIKEIKKEKFRIEDDAA 1586
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1079 QKSQ--------QLSALQEEN--VKLAEELGRTRDEVTSHQKLEEERSVL--NNQLLEMKKRESEFR--KDADEEKASLQ 1144
Cdd:TIGR01612 1587 KNDKsnkaaidiQLSLENFENkfLKISDIKKKINDCLKETESIEKKISSFsiDSQDTELKENGDNLNslQEFLESLKDQK 1666
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907165170 1145 KSISLTSALLTEKDAELEKLRN---------EVTVLRGENATAKSLHsvvQTLESDKVKLELKVKNL 1202
Cdd:TIGR01612 1667 KNIEDKKKELDELDSEIEKIEIdvdqhkknyEIGIIEKIKEIAIANK---EEIESIKELIEPTIENL 1730
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
719-1250 |
1.64e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 52.66 E-value: 1.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 719 TLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVnqvKETLEKELQTLKEkfastseeavsAQTRMQDTVNKLHQKEE 798
Cdd:TIGR00618 185 EFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHER---KQVLEKELKHLRE-----------ALQQTQQSHAYLTQKRE 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 799 QFNvlssELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLEND-----IAEIMKMSGDNSSQLTKMNDELRLKERSVEEL 873
Cdd:TIGR00618 251 AQE----EQLKKQQLLKQLRARIEELRAQEAVLEETQERINRArkaapLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKL 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 874 QLKLTKANENASFLQKSigevtlkaEQSQQQAARKHEEekkeleekllelekkMETSYNQCQDLKAKYEKASSET---KT 950
Cdd:TIGR00618 327 LMKRAAHVKQQSSIEEQ--------RRLLQTLHSQEIH---------------IRDAHEVATSIREISCQQHTLTqhiHT 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 951 KHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAR 1030
Cdd:TIGR00618 384 LQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQE 463
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1031 LQNELDTLKENnLKTVEEL-NKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVkLAEELGRTRDEVTSHQ 1109
Cdd:TIGR00618 464 SAQSLKEREQQ-LQTKEQIhLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGP-LTRRMQRGEQTYAQLE 541
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1110 KLEEErsvLNNQLLEMKKResefRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGE-NATAKSLHSVVQTL 1188
Cdd:TIGR00618 542 TSEED---VYHQLTSERKQ----RASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLtEKLSEAEDMLACEQ 614
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907165170 1189 ESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQIDFLNSVIVDLQRKNQ 1250
Cdd:TIGR00618 615 HALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLA 676
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
354-847 |
2.07e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.08 E-value: 2.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 354 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHvlELEAKMDQLRTMVEAADREKVELLNQLEEE 433
Cdd:COG4717 81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL--PLYQELEALEAELAELPERLEELEERLEEL 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 434 KRKVEDLQFRVEEesitkgdletQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRvatvsekSRIMELEKDLALRAQE 513
Cdd:COG4717 159 RELEEELEELEAE----------LAELQEELEELLEQLSLATEEELQDLAEELEELQ-------QRLAELEEELEEAQEE 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 514 VAELRRRLESSKPPGDVDMSLSLLQEISALQEKLEAIHTdHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESL 593
Cdd:COG4717 222 LEELEEELEQLENELEAAALEERLKEARLLLLIAAALLA-LLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 594 RSKLDHANkensdvialwksKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRlDYQHEIESLQSkqdser 673
Cdd:COG4717 301 GKEAEELQ------------ALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQ-ELLREAEELEE------ 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 674 sahakemetmQAKLMKIIKEKEDSLEAVKArlDSAEDqhLVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNq 753
Cdd:COG4717 362 ----------ELQLEELEQEIAALLAEAGV--EDEEE--LRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALD- 426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 754 vnqvKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEqfnvlSSELEKLRENLTDMEAKFKEKDDREDQLVK 833
Cdd:COG4717 427 ----EEELEEELEELEEELEELEEELEELREELAELEAELEQLEE-----DGELAELLQELEELKAELRELAEEWAALKL 497
|
490
....*....|....
gi 1907165170 834 AKEKLENDIAEIMK 847
Cdd:COG4717 498 ALELLEEAREEYRE 511
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
1027-1242 |
2.72e-06 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 52.22 E-value: 2.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1027 TNARLQNELDTLKENNLKTVEE------LNKSKELLsvenQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELG- 1099
Cdd:PRK11281 37 TEADVQAQLDALNKQKLLEAEDklvqqdLEQTLALL----DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDe 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1100 --RTRDEVTSHQKLEEERSVLNNQLLEMKKRESEfrkdADEEKASLQKSISLTSALLTEKDAELEKLRNEvtvLRGENAT 1177
Cdd:PRK11281 113 etRETLSTLSLRQLESRLAQTLDQLQNAQNDLAE----YNSQLVSLQTQPERAQAALYANSQRLQQIRNL---LKGGKVG 185
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907165170 1178 AKSLHSvvqtleSDKVKLELKVKNLELQLKENKRQLSSSSGNTD-AQAEEDERA-----QESQIDFLNSVI 1242
Cdd:PRK11281 186 GKALRP------SQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDlLQKQRDYLTariqrLEHQLQLLQEAI 250
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
481-868 |
3.09e-06 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 51.88 E-value: 3.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 481 KLQRELEDTRVATVSEKSRIMELEKDLAlraqEVAELRRRLESskppgDVDMS---LSLLQEISALQEKLEAIHTDhQGE 557
Cdd:COG3096 289 ELRRELFGARRQLAEEQYRLVEMARELE----ELSARESDLEQ-----DYQAAsdhLNLVQTALRQQEKIERYQED-LEE 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 558 MTS-LKEHFGAREEAfQKEIKALHTATEKLSKENESLRSKLdhankensdviALWKSKLET----AIASHQ--QAMEELK 630
Cdd:COG3096 359 LTErLEEQEEVVEEA-AEQLAEAEARLEAAEEEVDSLKSQL-----------ADYQQALDVqqtrAIQYQQavQALEKAR 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 631 VSFskGIGTDSAEFAELKTQIERLRLDYQHEiESLQSKQD-SERSAHAKEMETMQAKLMKIIKEKEDSLEAVKAR---LD 706
Cdd:COG3096 427 ALC--GLPDLTPENAEDYLAAFRAKEQQATE-EVLELEQKlSVADAARRQFEKAYELVCKIAGEVERSQAWQTARellRR 503
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 707 SAEDQHLVEMEDTLN-KLQEAEIKANsitkELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQ-- 783
Cdd:COG3096 504 YRSQQALAQRLQQLRaQLAELEQRLR----QQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVeq 579
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 784 -TRMQDTVNKLHQKEEQFN-------VLSSELEKLREN----LTDMEA----------KFKEKDDREDQLVKAKEKLEND 841
Cdd:COG3096 580 rSELRQQLEQLRARIKELAarapawlAAQDALERLREQsgeaLADSQEvtaamqqlleREREATVERDELAARKQALESQ 659
|
410 420
....*....|....*....|....*..
gi 1907165170 842 IAEIMKMSGDNSSQLtkmndeLRLKER 868
Cdd:COG3096 660 IERLSQPGGAEDPRL------LALAER 680
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
657-1131 |
4.43e-06 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 51.62 E-value: 4.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 657 DYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKaRLDSAEDQHLV-----EMEDTLNKLQEAEIKAN 731
Cdd:COG5022 814 SYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKK-RFSLLKKETIYlqsaqRVELAERQLQELKIDVK 892
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 732 SITK------ELQEKELVLT-GLQDSLNQVNQVKETLEKELQTLKEKfaSTSEEAVSAQTRMQDTVNKLHQKEeqfnvls 804
Cdd:COG5022 893 SISSlklvnlELESEIIELKkSLSSDLIENLEFKTELIARLKKLLNN--IDLEEGPSIEYVKLPELNKLHEVE------- 963
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 805 SELEKLRENLTDMeakFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSqLTKMNDELRLKERSVEELQLKLTKANENA 884
Cdd:COG5022 964 SKLKETSEEYEDL---LKKSTILVREGNKANSELKNFKKELAELSKQYGA-LQESTKQLKELPVEVAELQSASKIISSES 1039
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 885 SFL------QKSIGEVTLKAEQSQQQAarKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQN 958
Cdd:COG5022 1040 TELsilkplQKLKGLLLLENNQLQARY--KALKLRRENSLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVKPANVLQF 1117
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 959 LqkmladtedklkAAQEANRDLMQDMEELKTQadkakAAQTAEDAMQIME--QMTKEKTETLASLEDTKQTNARLQNELD 1036
Cdd:COG5022 1118 I------------VAQMIKLNLLQEISKFLSQ-----LVNTLEPVFQKLSvlQLELDGLFWEANLEALPSPPPFAALSEK 1180
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1037 TLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETL-KQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKL--EE 1113
Cdd:COG5022 1181 RLYQSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWpRGDKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMsnEK 1260
|
490 500
....*....|....*....|
gi 1907165170 1114 ERSVLN--NQLLEMKKRESE 1131
Cdd:COG5022 1261 LLSLLNsiDNLLSSYKLEEE 1280
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
645-906 |
4.56e-06 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 51.45 E-value: 4.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 645 AELKTQIERLRLDYQHEIESLQSKQDsersahakeMETMQAKLMKIIKEKEDsLEAVKARLDSAeDQHLVEMEDTLNKLQ 724
Cdd:PRK11281 39 ADVQAQLDALNKQKLLEAEDKLVQQD---------LEQTLALLDKIDRQKEE-TEQLKQQLAQA-PAKLRQAQAELEALK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 725 EaeiKANSITKELQEKeLVLTGLQDSLNQVNQvketlekELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLS 804
Cdd:PRK11281 108 D---DNDEETRETLST-LSLRQLESRLAQTLD-------QLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIR 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 805 SELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLEndiaeimKMSGDNSSQLTkmndELRLKERsvEELQLKLTKANENA 884
Cdd:PRK11281 177 NLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQ-------RKSLEGNTQLQ----DLLQKQR--DYLTARIQRLEHQL 243
|
250 260
....*....|....*....|..
gi 1907165170 885 SFLQKSIGEVTLkaEQSQQQAA 906
Cdd:PRK11281 244 QLLQEAINSKRL--TLSEKTVQ 263
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
357-1261 |
5.34e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 50.94 E-value: 5.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 357 KEKQQHIEQLLAERDLERAEVAKATSHVGE---IEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEE 433
Cdd:pfam01576 18 KERQQKAESELKELEKKHQQLCEEKNALQEqlqAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQLQNE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 434 KRK----VEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRE---LEDtrvatvseksRIMELEKD 506
Cdd:pfam01576 98 KKKmqqhIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKErklLEE----------RISEFTSN 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 507 LALRAQEVAELrrrlesskppgdvdmslsllqeiSALQEKLEAIHTDhqgemtslkehfgaREEAFQKEikalhtatEKL 586
Cdd:pfam01576 168 LAEEEEKAKSL-----------------------SKLKNKHEAMISD--------------LEERLKKE--------EKG 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 587 SKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKgigtdSAEFAELKTQIERLRLDYQHEIESLQ 666
Cdd:pfam01576 203 RQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALAR-----LEEETAQKNNALKKIRELEAQISELQ 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 667 SKQDSERSAHAKEMET---MQAKLMKIIKEKEDSLE--AVKARLDSAEDQHLVEMEDTLNklQEAEIKANSITKELQEKE 741
Cdd:pfam01576 278 EDLESERAARNKAEKQrrdLGEELEALKTELEDTLDttAAQQELRSKREQEVTELKKALE--EETRSHEAQLQEMRQKHT 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 742 LVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQ---FNVLSSELEKLRENLTDME 818
Cdd:pfam01576 356 QALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQlqeLQARLSESERQRAELAEKL 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 819 AKFKEKDDREDQLVKAKE----KLENDIAEImkmsgdnSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEv 894
Cdd:pfam01576 436 SKLQSELESVSSLLNEAEgkniKLSKDVSSL-------ESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEE- 507
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 895 tlkaEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKM------LADTED 968
Cdd:pfam01576 508 ----EEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLektknrLQQELD 583
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 969 KLKAAQEANRDLMQDMEELKTQAD------KAKAAQTAEDAMQIMEQ----------MTKEKTETLASLEDTKQTNARLQ 1032
Cdd:pfam01576 584 DLLVDLDHQRQLVSNLEKKQKKFDqmlaeeKAISARYAEERDRAEAEareketralsLARALEEALEAKEELERTNKQLR 663
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1033 NELDTL---KENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKS-------QQLSALQEENVKLAEELGRTR 1102
Cdd:pfam01576 664 AEMEDLvssKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKlrlevnmQALKAQFERDLQARDEQGEEK 743
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1103 DEVTSHQ------KLEEERSVLNNQLLEMKKRESEFRK------DADEEKASLQKSISLTSALLTEKDAELEKL---RNE 1167
Cdd:pfam01576 744 RRQLVKQvreleaELEDERKQRAQAVAAKKKLELDLKEleaqidAANKGREEAVKQLKKLQAQMKDLQRELEEArasRDE 823
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1168 VTVLRGEN-ATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERaqesqidfLNSVIVDLQ 1246
Cdd:pfam01576 824 ILAQSKESeKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRR--------LEARIAQLE 895
|
970
....*....|....*
gi 1907165170 1247 RKNQDLKMKVEMMSE 1261
Cdd:pfam01576 896 EELEEEQSNTELLND 910
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
425-1239 |
5.48e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 50.94 E-value: 5.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 425 ELLNQLEEEKRKVEDLQFRVEEESitkgdleTQTKLEHARTKElEQSLLFEKTKAD-KLQRELEDTRVATVSEKSRIMEL 503
Cdd:pfam01576 5 EEMQAKEEELQKVKERQQKAESEL-------KELEKKHQQLCE-EKNALQEQLQAEtELCAEAEEMRARLAARKQELEEI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 504 EKDLALRAQEVAELRRRLESSKPpgdvdmslSLLQEISALQEKLEAIHTDHQgEMTSLKEHFGAREEAFQKEIKALHTAT 583
Cdd:pfam01576 77 LHELESRLEEEEERSQQLQNEKK--------KMQQHIQDLEEQLDEEEAARQ-KLQLEKVTTEAKIKKLEEDILLLEDQN 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 584 EKLSKENESLRSKL----DHANKENSDVIALWKSKLEtaiasHQQAMEELKVSFSKGIGTdSAEFAELKTQIERLRLDYQ 659
Cdd:pfam01576 148 SKLSKERKLLEERIseftSNLAEEEEKAKSLSKLKNK-----HEAMISDLEERLKKEEKG-RQELEKAKRKLEGESTDLQ 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 660 HEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSaeDQHLVEMEDTLNKLQEAEIKANSITKELQE 739
Cdd:pfam01576 222 EQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIREL--EAQISELQEDLESERAARNKAEKQRRDLGE 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 740 K-ELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQD-------TVNKLHQKEEQFNVLSSELEKLR 811
Cdd:pfam01576 300 ElEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEmrqkhtqALEELTEQLEQAKRNKANLEKAK 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 812 ENL----TDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFL 887
Cdd:pfam01576 380 QALesenAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKL 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 888 QKSIGEVtlkaeQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEkassETKTKHEEILQNLQKMLADTE 967
Cdd:pfam01576 460 SKDVSSL-----ESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEE----EAKRNVERQLSTLQAQLSDMK 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 968 DKLKAAQEAnrdlMQDMEElktqaDKAKAAQTAEDAMQIMEqmtkEKTETLASLEDTKQtnaRLQNELDTLkennlktVE 1047
Cdd:pfam01576 531 KKLEEDAGT----LEALEE-----GKKRLQRELEALTQQLE----EKAAAYDKLEKTKN---RLQQELDDL-------LV 587
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1048 ELNKSKELLSVENQKMEEFKK---EIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQK-LEEERSVLNNQLL 1123
Cdd:pfam01576 588 DLDHQRQLVSNLEKKQKKFDQmlaEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEeLERTNKQLRAEME 667
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1124 EMKKRESEFRKDADE---EKASLQKSISLTSALLTEKDAELE-----KLRNEVTVLRGENATAKSLHSVVQTLESDKVKL 1195
Cdd:pfam01576 668 DLVSSKDDVGKNVHElerSKRALEQQVEEMKTQLEELEDELQatedaKLRLEVNMQALKAQFERDLQARDEQGEEKRRQL 747
|
810 820 830 840
....*....|....*....|....*....|....*....|....
gi 1907165170 1196 ELKVKNLELQLKENKRQLSSSSGnTDAQAEEDERAQESQIDFLN 1239
Cdd:pfam01576 748 VKQVRELEAELEDERKQRAQAVA-AKKKLELDLKELEAQIDAAN 790
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
759-1189 |
8.16e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.15 E-value: 8.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 759 ETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKL 838
Cdd:COG4717 49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 839 ENDIaeimkmsgdnssQLTKMNDELRLKERSVEELQLKLTKANEnasfLQKSIGEVTLKAEQSQQQAARKHEEEKKELEE 918
Cdd:COG4717 129 PLYQ------------ELEALEAELAELPERLEELEERLEELRE----LEEELEELEAELAELQEELEELLEQLSLATEE 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 919 KLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKML-ADTEDKLKAAQEANRD-------LMQDMEELKTQ 990
Cdd:COG4717 193 ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEaAALEERLKEARLLLLIaaallalLGLGGSLLSLI 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 991 ADKAKAAQTAEDAMQIMEQMT-KEKTETLASLEDTKQTNAR-------LQNELDTLKENNLKTVEELNKSKELLSVENQK 1062
Cdd:COG4717 273 LTIAGVLFLVLGLLALLFLLLaREKASLGKEAEELQALPALeeleeeeLEELLAALGLPPDLSPEELLELLDRIEELQEL 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1063 MEEFKKEIETLKQAAAQKSQQlSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEkaS 1142
Cdd:COG4717 353 LREAEELEEELQLEELEQEIA-ALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEE--E 429
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 1907165170 1143 LQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLE 1189
Cdd:COG4717 430 LEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQ 476
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
400-983 |
8.47e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 50.30 E-value: 8.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 400 QHVLELEAKMDQLRTMVEAADrEKVELLNQLEEEKRKVEDLQfRVEE--ESITkgdlETQTKLEHARTKELEQSLLFEKT 477
Cdd:COG4913 215 EYMLEEPDTFEAADALVEHFD-DLERAHEALEDAREQIELLE-PIRElaERYA----AARERLAELEYLRAALRLWFAQR 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 478 KADKLQRELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSkppgDVDMSLSLLQEISALQEKLEAI---HTDH 554
Cdd:COG4913 289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGN----GGDRLEQLEREIERLERELEERerrRARL 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 555 QGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALwKSKLETAIASHQQ-------AME 627
Cdd:COG4913 365 EALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE-LRELEAEIASLERrksnipaRLL 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 628 ELKVSFSKGIGTDSAE---FAEL----------KTQIERL-----------------------------RLDYQHEIESL 665
Cdd:COG4913 444 ALRDALAEALGLDEAElpfVGELievrpeeerwRGAIERVlggfaltllvppehyaaalrwvnrlhlrgRLVYERVRTGL 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 666 QSKQDSERSAHakemeTMQAKLmkIIKEKEdSLEAVKARLDSAEDQHLVEMEDTLNKLQEA-----EIKANSITKELQEK 740
Cdd:COG4913 524 PDPERPRLDPD-----SLAGKL--DFKPHP-FRAWLEAELGRRFDYVCVDSPEELRRHPRAitragQVKGNGTRHEKDDR 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 741 ELVLTGLQdsLNQVNQVK-ETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHqkeeqfnvLSSELEKLRENLTDMEA 819
Cdd:COG4913 596 RRIRSRYV--LGFDNRAKlAALEAELAELEEELAEAEERLEALEAELDALQERRE--------ALQRLAEYSWDEIDVAS 665
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 820 KFKEKDDREDQLvkakEKLENDiaeimkmsgdnSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEvtlkAE 899
Cdd:COG4913 666 AEREIAELEAEL----ERLDAS-----------SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQ----AE 726
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 900 QSQQQAARKHEEEKKELEEKLLelekkmetsynqcQDLKAKYEKASSETKTKheEILQNLQKMLADTEDKLKAAQEANRD 979
Cdd:COG4913 727 EELDELQDRLEAAEDLARLELR-------------ALLEERFAAALGDAVER--ELRENLEERIDALRARLNRAEEELER 791
|
....
gi 1907165170 980 LMQD 983
Cdd:COG4913 792 AMRA 795
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
570-786 |
1.02e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.38 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 570 EAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALWKsKLETAIASHQQAMEELKvsfskgigtdsAEFAELKT 649
Cdd:COG4942 30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR-ALEQELAALEAELAELE-----------KEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 650 QIERLRLDYQHEIESLQ--SKQD-------SERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTL 720
Cdd:COG4942 98 ELEAQKEELAELLRALYrlGRQPplalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907165170 721 NKLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRM 786
Cdd:COG4942 178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
569-842 |
1.69e-05 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 49.26 E-value: 1.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 569 EEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAEfaELK 648
Cdd:pfam05667 253 AEQLRSAALAGTEATSGASRSAQDLAELLSSFSGSSTTDTGLTKGSRFTHTEKLQFTNEAPAATSSPPTKVETEE--ELQ 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 649 TQIERLRLDYQHEIESLQSKQDsersAHAKEMETMQAKlmkiIKEKEDSLEAVKARLDSAEDQHLVeMEDTLNKLQEAE- 727
Cdd:pfam05667 331 QQREEELEELQEQLEDLESSIQ----ELEKEIKKLESS----IKQVEEELEELKEQNEELEKQYKV-KKKTLDLLPDAEe 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 728 --IKANSITKELQEKELVLTGlqdslnQVNQVKETLEKELQTLKEKfastseeavsAQTRMQDTVNKLhqkeeqfnvlsS 805
Cdd:pfam05667 402 niAKLQALVDASAQRLVELAG------QWEKHRVPLIEEYRALKEA----------KSNKEDESQRKL-----------E 454
|
250 260 270
....*....|....*....|....*....|....*..
gi 1907165170 806 ELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDI 842
Cdd:pfam05667 455 EIKELREKIKEVAEEAKQKEELYKQLVAEYERLPKDV 491
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
410-1065 |
2.04e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 49.27 E-value: 2.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 410 DQLRTMVEAADREKVE-------LLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKAdkl 482
Cdd:TIGR00606 419 SKERLKQEQADEIRDEkkglgrtIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSL--- 495
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 483 qreLEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKppgdvdMSLSLLQEISALQEKLEAIHTDHQGEMTSLK 562
Cdd:TIGR00606 496 ---TETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRT------QMEMLTKDKMDKDEQIRKIKSRHSDELTSLL 566
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 563 EHFGAREE------AFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIA---------------------LWKSKL 615
Cdd:TIGR00606 567 GYFPNKKQledwlhSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEqlssyedklfdvcgsqdeesdLERLKE 646
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 616 ETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKE 695
Cdd:TIGR00606 647 EIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRD 726
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 696 DSLEAVKARlDSAEDQHLVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVN------QVKETLEKELQTLK 769
Cdd:TIGR00606 727 EMLGLAPGR-QSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKvcltdvTIMERFQMELKDVE 805
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 770 EKFASTSEE--AVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRenltdmeakfKEKDDREDQLVKAKEKLENDIAEIMK 847
Cdd:TIGR00606 806 RKIAQQAAKlqGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNR----------KLIQDQQEQIQHLKSKTNELKSEKLQ 875
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 848 MsGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGevtlKAEQSQQQAARKHEEEKKELEEKLLELEKKM 927
Cdd:TIGR00606 876 I-GTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLE----KDQQEKEELISSKETSNKKAQDKVNDIKEKV 950
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 928 ETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTaedaMQIM 1007
Cdd:TIGR00606 951 KNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLT----LRKR 1026
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907165170 1008 EQMTKEKTETLAS---------LEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEE 1065
Cdd:TIGR00606 1027 ENELKEVEEELKQhlkemgqmqVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELRE 1093
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
334-824 |
2.12e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 48.95 E-value: 2.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 334 LLTETSSRYARKISGTTALQ-EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQL 412
Cdd:pfam05483 261 FLLEESRDKANQLEEKTKLQdENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEEL 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 413 R----------TMVEAADREKVELLNQLEEEKRKVED-LQFRVEEESITKGDLETQTKLEHARTKELE---------QSL 472
Cdd:pfam05483 341 NkakaahsfvvTEFEATTCSLEELLRTEQQRLEKNEDqLKIITMELQKKSSELEEMTKFKNNKEVELEelkkilaedEKL 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 473 LFEKTKADKLQRELEDTRVATV----SEKSRIMELEKDLAL-------RAQEVAELRRRLESSKPP-----GDVDMSL-- 534
Cdd:pfam05483 421 LDEKKQFEKIAEELKGKEQELIfllqAREKEIHDLEIQLTAiktseehYLKEVEDLKTELEKEKLKnieltAHCDKLLle 500
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 535 --SLLQEISALQEKLEaihtDHQGEMTSLKEhfgaREEAFQKEIKALHTATEKLSKENESLRSKLDHANKEnsdvialWK 612
Cdd:pfam05483 501 nkELTQEASDMTLELK----KHQEDIINCKK----QEERMLKQIENLEEKEMNLRDELESVREEFIQKGDE-------VK 565
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 613 SKLETAiASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERlRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIik 692
Cdd:pfam05483 566 CKLDKS-EENARSIEYEVLKKEKQMKILENKCNNLKKQIEN-KNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKL-- 641
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 693 ekEDSLEAVKARLDSAEDQHLVEMEDT-------LNKLQEAEIKANSITKELQEKEL--------VLTGLQDSLNQVNQV 757
Cdd:pfam05483 642 --ELELASAKQKFEEIIDNYQKEIEDKkiseeklLEEVEKAKAIADEAVKLQKEIDKrcqhkiaeMVALMEKHKHQYDKI 719
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907165170 758 KETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEK 824
Cdd:pfam05483 720 IEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDK 786
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1049-1252 |
2.19e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 48.86 E-value: 2.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1049 LNKSKELLSVENQKMEEF-KKEIETLKQAAAQKSQQLSALQEEN--VKLAEELGRTRDEVTShqkLEEERSVLNNQLLEM 1125
Cdd:COG3206 162 LEQNLELRREEARKALEFlEEQLPELRKELEEAEAALEEFRQKNglVDLSEEAKLLLQQLSE---LESQLAEARAELAEA 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1126 KKRESEFRKDADEEKASLqkSISLTSALLTEKDAELEKLRNEVTVLRgenATAKSLHSVVQTLESdkvklelKVKNLELQ 1205
Cdd:COG3206 239 EARLAALRAQLGSGPDAL--PELLQSPVIQQLRAQLAELEAELAELS---ARYTPNHPDVIALRA-------QIAALRAQ 306
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1907165170 1206 LKENKRQLSSSSGNTDAQAEEDERAQESQIDFLNSVIVDLQRKNQDL 1252
Cdd:COG3206 307 LQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAEL 353
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
956-1173 |
2.30e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.14 E-value: 2.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 956 LQNLQKMLADTEDKLKAAQEAnRDLMQDMEELKTQADKA---KAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQ 1032
Cdd:COG4913 237 LERAHEALEDAREQIELLEPI-RELAERYAAARERLAELeylRAALRLWFAQRRLELLEAELEELRAELARLEAELERLE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1033 NELDTLKEnnlkTVEELnkSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEenvkLAEELGrtrdevtshQKLE 1112
Cdd:COG4913 316 ARLDALRE----ELDEL--EAQIRGNGGDRLEQLEREIERLERELEERERRRARLEA----LLAALG---------LPLP 376
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907165170 1113 EERSvlnnQLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRG 1173
Cdd:COG4913 377 ASAE----EFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
544-1286 |
2.52e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 48.89 E-value: 2.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 544 QEKLEAIHTDHQGEMtslKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKEN-SDVIALWKSKLETAIASH 622
Cdd:TIGR00606 188 LETLRQVRQTQGQKV---QEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENeLDPLKNRLKEIEHNLSKI 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 623 QQAMEELKvSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKE-KEDSLEAV 701
Cdd:TIGR00606 265 MKLDNEIK-ALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKErRLLNQEKT 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 702 KARLDSAEDQHLVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVS 781
Cdd:TIGR00606 344 ELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERL 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 782 AQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSgDNSSQLTKMND 861
Cdd:TIGR00606 424 KQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAE-KNSLTETLKKE 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 862 ELRLKERSVEELQLKLTKANENAsflQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKY 941
Cdd:TIGR00606 503 VKSLQNEKADLDRKLRKLDQEME---QLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWL 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 942 EKASSEtKTKHEEILQNLQKMLADTE---------DKLKAAQEAN-----------RDLMQDMEELKTQADKAK---AAQ 998
Cdd:TIGR00606 580 HSKSKE-INQTRDRLAKLNKELASLEqnknhinneLESKEEQLSSyedklfdvcgsQDEESDLERLKEEIEKSSkqrAML 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 999 TAEDAM--QIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQA 1076
Cdd:TIGR00606 659 AGATAVysQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSI 738
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1077 AAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEE--------------ERSVLNNQLLEMKKRESEFRKDADEEKAS 1142
Cdd:TIGR00606 739 IDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGtimpeeesakvcltDVTIMERFQMELKDVERKIAQQAAKLQGS 818
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1143 -LQKSISLTSALLTEKDAELEKLRNEVTVLRG----ENATAKSLHSVVQTLESDKVKLELKVKN---LELQLKENKRQLS 1214
Cdd:TIGR00606 819 dLDRTVQQVNQEKQEKQHELDTVVSKIELNRKliqdQQEQIQHLKSKTNELKSEKLQIGTNLQRrqqFEEQLVELSTEVQ 898
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907165170 1215 SSSGNTDAQAEEDERAQESQIDFLNSVIVDLQRKNQDLK---MKVEMMSEAALN--GNGEDLNSYDSDDQEKQSKKK 1286
Cdd:TIGR00606 899 SLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKkaqDKVNDIKEKVKNihGYMKDIENKIQDGKDDYLKQK 975
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
826-1040 |
2.96e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 2.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 826 DREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLK-AEQSQQQ 904
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEiAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 905 AARKHEEEKKELEEKLLELEKKMETSYNQCQDLKA----KYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDL 980
Cdd:COG4942 100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAvrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 981 MQDMEELKTQADKAKAAQTaedamQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKE 1040
Cdd:COG4942 180 LAELEEERAALEALKAERQ-----KLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
427-1073 |
3.26e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 48.48 E-value: 3.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 427 LNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKD 506
Cdd:TIGR04523 126 LNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSN 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 507 LALRAQEVAELRRRLESSKPPGDV--DMSLSLLQEISALQEKLEAIHTDHQgEMTSLKEHFGAREEAFQKEIKALHTATE 584
Cdd:TIGR04523 206 LKKKIQKNKSLESQISELKKQNNQlkDNIEKKQQEINEKTTEISNTQTQLN-QLKDEQNKIKKQLSEKQKELEQNNKKIK 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 585 KLSKENESLRSKLDHANKENSDVialWKSKLETAIASHQQAMEELKVSFSKGIGTDSaefaELKTQIERLRLDYQHeies 664
Cdd:TIGR04523 285 ELEKQLNQLKSEISDLNNQKEQD---WNKELKSELKNQEKKLEEIQNQISQNNKIIS----QLNEQISQLKKELTN---- 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 665 lqskQDSERSAHAKEMETMQAKLMKIIKEKE---DSLEAVKARLDSAEDQhlVEMEDTLNKLQEAEIKANSITKELQEKE 741
Cdd:TIGR04523 354 ----SESENSEKQRELEEKQNEIEKLKKENQsykQEIKNLESQINDLESK--IQNQEKLNQQKDEQIKKLQQEKELLEKE 427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 742 LVLTGLQ--------DSLNQVNQVKETLEKELQTLKEKFaSTSEEAVSAQTRMQDTvnKLHQKEEQFNVLSSELEKLREN 813
Cdd:TIGR04523 428 IERLKETiiknnseiKDLTNQDSVKELIIKNLDNTRESL-ETQLKVLSRSINKIKQ--NLEQKQKELKSKEKELKKLNEE 504
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 814 LTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELR--LKERSVEELQLKLTKANENASFLQKSI 891
Cdd:TIGR04523 505 KKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKkeNLEKEIDEKNKEIEELKQTQKSLKKKQ 584
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 892 GEVTLKAEQSQQQaarkheeeKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSEtKTKHEEILQNLQKMLADTEDKLK 971
Cdd:TIGR04523 585 EEKQELIDQKEKE--------KKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSI-IKNIKSKKNKLKQEVKQIKETIK 655
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 972 AAQEANRDLMQDMEELKTQADkakaaqtaeDAMQIMEQMTKEKTETlaslEDTKQTNARLQNELDTLKENNLKTVEELnk 1051
Cdd:TIGR04523 656 EIRNKWPEIIKKIKESKTKID---------DIIELMKDWLKELSLH----YKKYITRMIRIKDLPKLEEKYKEIEKEL-- 720
|
650 660
....*....|....*....|..
gi 1907165170 1052 skellsvenQKMEEFKKEIETL 1073
Cdd:TIGR04523 721 ---------KKLDEFSKELENI 733
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
684-847 |
3.31e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 48.24 E-value: 3.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 684 QAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEM-EDTLNKLQEAEIKANSITKELQEKElvltglqdslNQVNQVKETLE 762
Cdd:PRK12704 30 EAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAkEEIHKLRNEFEKELRERRNELQKLE----------KRLLQKEENLD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 763 KELQTLKEKfastseeavsaQTRMQDTVNKLHQKEEQFNVLSSELEKLRE----------NLTDMEAKfkekddrEDQLV 832
Cdd:PRK12704 100 RKLELLEKR-----------EEELEKKEKELEQKQQELEKKEEELEELIEeqlqelerisGLTAEEAK-------EILLE 161
|
170
....*....|....*
gi 1907165170 833 KAKEKLENDIAEIMK 847
Cdd:PRK12704 162 KVEEEARHEAAVLIK 176
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
347-603 |
3.38e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 3.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 347 SGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlardghdqhvlELEAKMDQLRTMVEAADREKVEL 426
Cdd:COG4942 13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-----------ALERRIAALARRIRALEQELAAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 427 LNQLEEEKRKVEDLQFRVEEEsitKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKD 506
Cdd:COG4942 82 EAELAELEKEIAELRAELEAQ---KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 507 LalraQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKehfgAREEAFQKEIKALHTATEKL 586
Cdd:COG4942 159 L----AELAALRAELEAER-----AELEALLAELEEERAALEALKAERQKLLARLE----KELAELAAELAELQQEAEEL 225
|
250
....*....|....*..
gi 1907165170 587 SKENESLRSKLDHANKE 603
Cdd:COG4942 226 EALIARLEAEAAAAAER 242
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
418-655 |
3.47e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 3.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 418 AADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEK 497
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 498 SRIMELEKDLA--LRAQEVAELRRRLE---SSKPPGDVDMSLSLLQEIS-ALQEKLEAIHTDHQgemtslkehfgaREEA 571
Cdd:COG4942 97 AELEAQKEELAelLRALYRLGRQPPLAlllSPEDFLDAVRRLQYLKYLApARREQAEELRADLA------------ELAA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 572 FQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIAlwksKLETAIASHQQAMEELKvsfskgigtdsAEFAELKTQI 651
Cdd:COG4942 165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLA----RLEKELAELAAELAELQ-----------QEAEELEALI 229
|
....
gi 1907165170 652 ERLR 655
Cdd:COG4942 230 ARLE 233
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
994-1230 |
3.68e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 3.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 994 AKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKEnnlktveELNKSKELLSVENQKMEEFKKEIETL 1073
Cdd:COG4942 16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALER-------RIAALARRIRALEQELAALEAELAEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1074 KQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISLTSAL 1153
Cdd:COG4942 89 EKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907165170 1154 LTEKDAELEKLRNEVTVLRGENATAKSLH-SVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERA 1230
Cdd:COG4942 169 LEAERAELEALLAELEEERAALEALKAERqKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
622-1293 |
4.42e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 48.12 E-value: 4.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 622 HQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEkedsleaV 701
Cdd:TIGR01612 669 YEDDIDALYNELSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVE-------I 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 702 KARLDSAEDQHLVE-MEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVN-----------QVKETLEK------ 763
Cdd:TIGR01612 742 KKHIHGEINKDLNKiLEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKNHYNdqinidnikdeDAKQNYDKskeyik 821
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 764 --------------ELQTLKEKFASTSEEAVSAQTRMQDTVNKLHqkeEQFNVLSSEL--EKLRENLTDMEAKFKEKddr 827
Cdd:TIGR01612 822 tisikedeifkiinEMKFMKDDFLNKVDKFINFENNCKEKIDSEH---EQFAELTNKIkaEISDDKLNDYEKKFNDS--- 895
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 828 edqlvkakEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGevTLKAEQSQQQAAR 907
Cdd:TIGR01612 896 --------KSLINEINKSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEILNKNID--TIKESNLIEKSYK 965
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 908 KHEEekkeleekllelekkmETSYNQCQDLKAKYEKAS-SETKTKHEEILQ---NLQKMLADTEDKLKAAQ-----EANR 978
Cdd:TIGR01612 966 DKFD----------------NTLIDKINELDKAFKDASlNDYEAKNNELIKyfnDLKANLGKNKENMLYHQfdekeKATN 1029
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 979 DLMQDMEELKTQADKAKAAqTAEDAMQIMEQMTKEKTETLASLE-------DTKQTN-------ARLQNELDTLKENNLK 1044
Cdd:TIGR01612 1030 DIEQKIEDANKNIPNIEIA-IHTSIYNIIDEIEKEIGKNIELLNkeileeaEINITNfneikekLKHYNFDDFGKEENIK 1108
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1045 TVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAeelgrtrdevtshqkleeERSVLNNQLLE 1124
Cdd:TIGR01612 1109 YADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVA------------------DKAISNDDPEE 1170
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1125 MKKRESEFRKDADEEKASLQksisltsalltekdaELEKLRNEVTvlrgenatakslhsvvqTLESDKVKLElKVKNLEL 1204
Cdd:TIGR01612 1171 IEKKIENIVTKIDKKKNIYD---------------EIKKLLNEIA-----------------EIEKDKTSLE-EVKGINL 1217
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1205 QLKENKRQLSSSsgntdaQAEEDERAQESQIDFLNSVIVDLQR-KNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQ- 1282
Cdd:TIGR01612 1218 SYGKNLGKLFLE------KIDEEKKKSEHMIKAMEAYIEDLDEiKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHi 1291
|
730
....*....|..
gi 1907165170 1283 -SKKKPRLFCDI 1293
Cdd:TIGR01612 1292 iSKKHDENISDI 1303
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
1040-1286 |
4.51e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 47.64 E-value: 4.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1040 ENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSA-LQEENVKLAEELGRTRD---EVTSHQKLEEER 1115
Cdd:COG5185 232 EEALKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKrLNENANNLIKQFENTKEkiaEYTKSIDIKKAT 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1116 SVLNNQLLEMKKrESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKS---LHSVVQTLESDK 1192
Cdd:COG5185 312 ESLEEQLAAAEA-EQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKSseeLDSFKDTIESTK 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1193 VKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERaqesQIDFLNSVIVDLQRKNQDL-KMKVEMMSEAALNGNGEDL 1271
Cdd:COG5185 391 ESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQR----QIEQATSSNEEVSKLLNELiSELNKVMREADEESQSRLE 466
|
250
....*....|....*
gi 1907165170 1272 NSYDSDDQEKQSKKK 1286
Cdd:COG5185 467 EAYDEINRSVRSKKE 481
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
711-845 |
4.98e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.46 E-value: 4.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 711 QHLVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMqdtv 790
Cdd:COG1579 7 RALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQL---- 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1907165170 791 nKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEI 845
Cdd:COG1579 83 -GNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAEL 136
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
965-1167 |
6.08e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.60 E-value: 6.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 965 DTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNlK 1044
Cdd:COG4913 607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASS-D 685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1045 TVEELnkskellsvenqkmeefKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLN----N 1120
Cdd:COG4913 686 DLAAL-----------------EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLArlelR 748
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1907165170 1121 QLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNE 1167
Cdd:COG4913 749 ALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
658-1210 |
6.51e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 47.74 E-value: 6.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 658 YQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKAnsitkel 737
Cdd:TIGR01612 472 FEEEWGSYDIKKDIDENSKQDNTVKLILMRMKDFKDIIDFMELYKPDEVPSKNIIGFDIDQNIKAKLYKEIEA------- 544
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 738 qekelvltGLQDSLNQVNQVKETLEKelqtLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQ---FNVLSSELEKLRENL 814
Cdd:TIGR01612 545 --------GLKESYELAKNWKKLIHE----IKKELEEENEDSIHLEKEIKDLFDKYLEIDDEiiyINKLKLELKEKIKNI 612
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 815 TDmeakfkeKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTkmnDELRLKERSVEELQLKLTKA---------NENAS 885
Cdd:TIGR01612 613 SD-------KNEYIKKAIDLKKIIENNNAYIDELAKISPYQVP---EHLKNKDKIYSTIKSELSKIyeddidalyNELSS 682
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 886 FLQKSI---GEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASsetktkHEEILQNLQKM 962
Cdd:TIGR01612 683 IVKENAidnTEDKAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHI------HGEINKDLNKI 756
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 963 LADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTA------------EDAMQIMEQmTKEKTETLASLEDtkqTNAR 1030
Cdd:TIGR01612 757 LEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKNHyndqinidnikdEDAKQNYDK-SKEYIKTISIKED---EIFK 832
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1031 LQNELDTLKEnnlktvEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQ----EENVKLAEELgrtRDEVT 1106
Cdd:TIGR01612 833 IINEMKFMKD------DFLNKVDKFINFENNCKEKIDSEHEQFAELTNKIKAEISDDKlndyEKKFNDSKSL---INEIN 903
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1107 shQKLEEERSVLNNQllemkKRESEFRKDADEEKASLQKsisltsalLTEKDAEL-EKLRNEVTVLRGENATAKSLHSVV 1185
Cdd:TIGR01612 904 --KSIEEEYQNINTL-----KKVDEYIKICENTKESIEK--------FHNKQNILkEILNKNIDTIKESNLIEKSYKDKF 968
|
570 580
....*....|....*....|....*.
gi 1907165170 1186 Q-TLESDKVKLELKVKNLELQLKENK 1210
Cdd:TIGR01612 969 DnTLIDKINELDKAFKDASLNDYEAK 994
|
|
| COG4487 |
COG4487 |
Uncharacterized conserved protein, contains DUF2130 domain [Function unknown]; |
935-1084 |
6.76e-05 |
|
Uncharacterized conserved protein, contains DUF2130 domain [Function unknown];
Pssm-ID: 443580 [Multi-domain] Cd Length: 425 Bit Score: 46.86 E-value: 6.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 935 QDLKAKYEKASSETKTKHEEILQNLQKMLADTEDK--LKAAQEANRDLMQDMEELKTQADKAKAAQTAEdamqiMEQMTK 1012
Cdd:COG4487 50 ELAEAKAKAQLQEQVAEKDAEIAELRARLEAEERKkaLAVAEEKEKELAALQEALAEKDAKLAELQAKE-----LELLKK 124
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907165170 1013 EKTETLASLEDTKQTNARLQNELDTLKEN-NLKTVEELNKSKELLSVENQK-MEEFKKEIETLKQAAAQKSQQL 1084
Cdd:COG4487 125 ERELEDAKREAELTVEKERDEELDELKEKlKKEEEEKQLAEKSLKVAEYEKqLKDMQEQIEELKRKKEQGSTQL 198
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1029-1174 |
6.79e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.07 E-value: 6.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1029 ARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRD--EVT 1106
Cdd:COG1579 13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNnkEYE 92
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907165170 1107 SHQK----LEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGE 1174
Cdd:COG1579 93 ALQKeiesLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
776-1164 |
9.75e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 47.26 E-value: 9.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 776 SEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDR-------------EDQLVKAKEKLENDI 842
Cdd:PRK04863 285 LEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHlnlvqtalrqqekIERYQADLEELEERL 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 843 AEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKsigevtlKAEQSQQ--QAARKHEEEKKELEEKL 920
Cdd:PRK04863 365 EEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQT-------RAIQYQQavQALERAKQLCGLPDLTA 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 921 LELEKKMETSYNQCQDLKAKYEKA------SSETKTKHEEILQNLQKMLADTEDklKAAQEANRDLMQDMEELKTQADKA 994
Cdd:PRK04863 438 DNAEDWLEEFQAKEQEATEELLSLeqklsvAQAAHSQFEQAYQLVRKIAGEVSR--SEAWDVARELLRRLREQRHLAEQL 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 995 KAAQTA-----------EDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKennlktvEELNKSKELLSVENQKM 1063
Cdd:PRK04863 516 QQLRMRlseleqrlrqqQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLS-------ESVSEARERRMALRQQL 588
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1064 EEFKKEIETLkqaaAQKSQQLSALQEENVKLAEELGrtrDEVTSHQKLEEERSvlnnQLLEMKKRESEFRKDADEEKASL 1143
Cdd:PRK04863 589 EQLQARIQRL----AARAPAWLAAQDALARLREQSG---EEFEDSQDVTEYMQ----QLLERERELTVERDELAARKQAL 657
|
410 420
....*....|....*....|.
gi 1907165170 1144 QKSISLTSALLTEKDAELEKL 1164
Cdd:PRK04863 658 DEEIERLSQPGGSEDPRLNAL 678
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
931-1107 |
1.13e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.98 E-value: 1.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 931 YNQCQDLKAKYEKASSETKTKHEEIlQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADK------AKAAQTAEDAM 1004
Cdd:COG3883 43 QAELEELNEEYNELQAELEALQAEI-DKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYldvllgSESFSDFLDRL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1005 QIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLsveNQKMEEFKKEIETLKQAAAQKSQQL 1084
Cdd:COG3883 122 SALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL---EAQQAEQEALLAQLSAEEAAAEAQL 198
|
170 180
....*....|....*....|...
gi 1907165170 1085 SALQEENVKLAEELGRTRDEVTS 1107
Cdd:COG3883 199 AELEAELAAAEAAAAAAAAAAAA 221
|
|
| CLIP1_ZNF |
pfam16641 |
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ... |
1288-1305 |
1.18e-04 |
|
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.
Pssm-ID: 465212 Cd Length: 17 Bit Score: 40.14 E-value: 1.18e-04
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
776-1088 |
1.36e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 46.44 E-value: 1.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 776 SEEAVSAQTrmqDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQ 855
Cdd:PRK11281 37 TEADVQAQL---DALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEE 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 856 LTKmndelRLKERSVEELQLKLTKANENASFLQKSIGEVT--LKAEQSQQQAARKheeekkeleekllelekKMETSYNQ 933
Cdd:PRK11281 114 TRE-----TLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNsqLVSLQTQPERAQA-----------------ALYANSQR 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 934 CQDLKA--KYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMeeLKTQADKAKAAQTAEDAMQIMEQ-- 1009
Cdd:PRK11281 172 LQQIRNllKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDL--LQKQRDYLTARIQRLEHQLQLLQea 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1010 -------MTKEKTETLASLEDT--KQTNARLQNELDT---LKENNLKTVEELNKskelLSVENQKMeefKKEIETLKQAA 1077
Cdd:PRK11281 250 inskrltLSEKTVQEAQSQDEAarIQANPLVAQELEInlqLSQRLLKATEKLNT----LTQQNLRV---KNWLDRLTQSE 322
|
330
....*....|.
gi 1907165170 1078 AQKSQQLSALQ 1088
Cdd:PRK11281 323 RNIKEQISVLK 333
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
571-799 |
1.36e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 1.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 571 AFQKEIKALHTATEKLSKENESLRSKLDHANKEnsdvialwKSKLETAIASHQQAMEELkvsfSKGIGTDSAEFAELKTQ 650
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKE--------EKALLKQLAALERRIAAL----ARRIRALEQELAALEAE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 651 IERLrldyQHEIESLQSKQDSERSAHAKEMETMQ----AKLMKIIKEKEDSLEAVKA-----RLDSAEDQHLVEMEDTLN 721
Cdd:COG4942 85 LAEL----EKEIAELRAELEAQKEELAELLRALYrlgrQPPLALLLSPEDFLDAVRRlqylkYLAPARREQAEELRADLA 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907165170 722 KLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQ 799
Cdd:COG4942 161 ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
351-904 |
1.90e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 45.97 E-value: 1.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 351 ALQEALKeKQQHIEQLL-AERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQ 429
Cdd:pfam10174 78 ALQDELR-AQRDLNQLLqQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGAR 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 430 LEEEKRKVEDLQFRVEEESITKGDLE--TQTKLEHARTKELEqSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDL 507
Cdd:pfam10174 157 DESIKKLLEMLQSKGLPKKSGEEDWErtRRIAEAEMQLGHLE-VLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVI 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 508 ALRAQEVAELRRRLESskppgdvdmslsLLQEISALQEKLEAIHTDHQGEMTSL----------KEHFGAREEAFQK--- 574
Cdd:pfam10174 236 EMKDTKISSLERNIRD------------LEDEVQMLKTNGLLHTEDREEEIKQMevykshskfmKNKIDQLKQELSKkes 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 575 EIKALHTATEKLSKEN-----------ESLRSKLDHANKENSDVIALWK--SKLETAIASHQQAMEELkvsfSKGIGTDS 641
Cdd:pfam10174 304 ELLALQTKLETLTNQNsdckqhievlkESLTAKEQRAAILQTEVDALRLrlEEKESFLNKKTKQLQDL----TEEKSTLA 379
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 642 AEFAELKTQI---ERLRLDYQHEIESLQS------KQDSERSAHAKEME-------TMQAKLMKIIKEKEDSLEAVKARL 705
Cdd:pfam10174 380 GEIRDLKDMLdvkERKINVLQKKIENLQEqlrdkdKQLAGLKERVKSLQtdssntdTALTTLEEALSEKERIIERLKEQR 459
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 706 DSAEDQHLVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQD---SLNQVNQVKE----TLEKELQTLKEKF------ 772
Cdd:pfam10174 460 EREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEhasSLASSGLKKDsklkSLEIAVEQKKEECsklenq 539
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 773 ---ASTSEEAVSAQTRMQDTVNKLHQ----KEEQFNVLSSELEKLRENLTDMEakfKEKDDREdqlvKAKEKLENDIAEI 845
Cdd:pfam10174 540 lkkAHNAEEAVRTNPEINDRIRLLEQevarYKEESGKAQAEVERLLGILREVE---NEKNDKD----KKIAELESLTLRQ 612
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*....
gi 1907165170 846 MKMSGDNSSQLTKMNDELRLKERSVEELQLKlTKANENASFLQKSIGEVTLKAEQSQQQ 904
Cdd:pfam10174 613 MKEQNKKVANIKHGQQEMKKKGAQLLEEARR-REDNLADNSQQLQLEELMGALEKTRQE 670
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
759-877 |
1.96e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 45.62 E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 759 ETLEKELQTLKEKfaSTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDR----EDQLVKA 834
Cdd:COG2433 376 LSIEEALEELIEK--ELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERierlERELSEA 453
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1907165170 835 KEKLENDI---AEIMKMSGDNsSQLTKmndELRLKERSVEELQLKL 877
Cdd:COG2433 454 RSEERREIrkdREISRLDREI-ERLER---ELEEERERIEELKRKL 495
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
410-588 |
1.99e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.78 E-value: 1.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 410 DQLRTMVEAADREKVELLNQLEEEKRKVEDLQ-----FRVEEESItkgDLETQTKLEHARTKELEQSLL-------FEKT 477
Cdd:COG3206 164 QNLELRREEARKALEFLEEQLPELRKELEEAEaaleeFRQKNGLV---DLSEEAKLLLQQLSELESQLAearaelaEAEA 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 478 KADKLQRELEDTR--VATVSEKSRIMELEKDLALRAQEVAELRRRLESSKPpgDVdmsLSLLQEISALQEKLEAIHTDHQ 555
Cdd:COG3206 241 RLAALRAQLGSGPdaLPELLQSPVIQQLRAQLAELEAELAELSARYTPNHP--DV---IALRAQIAALRAQLQQEAQRIL 315
|
170 180 190
....*....|....*....|....*....|...
gi 1907165170 556 GEMTSLKEHFGAREEAFQKEIKALHTATEKLSK 588
Cdd:COG3206 316 ASLEAELEALQAREASLQAQLAQLEARLAELPE 348
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
381-813 |
2.15e-04 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 45.60 E-value: 2.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 381 TSHVGEIEQELALARDGHDQ-HVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEeesitkgdlETQTK 459
Cdd:PRK04778 78 TNSLPDIEEQLFEAEELNDKfRFRKAKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVE---------QLKDL 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 460 LEHARTKELEQSLLFEKTkADKLQRELED-----TRVATVSEKSRIMELEKDLALRAQEVAELRRRLEsskppgdvdmsl 534
Cdd:PRK04778 149 YRELRKSLLANRFSFGPA-LDELEKQLENleeefSQFVELTESGDYVEAREILDQLEEELAALEQIME------------ 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 535 sllqEISALQEKLEaihTDHQGEMTSLK--------EHFGAREEAFQKEIKALHTATEKLSKENESLrsKLDHANKENSD 606
Cdd:PRK04778 216 ----EIPELLKELQ---TELPDQLQELKagyrelveEGYHLDHLDIEKEIQDLKEQIDENLALLEEL--DLDEAEEKNEE 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 607 V---IALWKSKLETAIASHQQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQ---HEIESLQSkqdsersaHAKEM 680
Cdd:PRK04778 287 IqerIDQLYDILEREVKARKYVEKNSDT-LPDFLEHAKEQNKELKEEIDRVKQSYTlneSELESVRQ--------LEKQL 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 681 ETMQAKLMKIIK----------EKEDSLEAVKARLDSAEDQHlVEMEDTLNKLQEAEIKANSITKEL-QEKELV------ 743
Cdd:PRK04778 358 ESLEKQYDEITEriaeqeiaysELQEELEEILKQLEEIEKEQ-EKLSEMLQGLRKDELEAREKLERYrNKLHEIkrylek 436
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907165170 744 --LTGL-QDSLNQVNQVKETLEKELQTLKEKfastseeavsaQTRMQDTVNKLHQKEEQFNVLSSELEKLREN 813
Cdd:PRK04778 437 snLPGLpEDYLEMFFEVSDEIEALAEELEEK-----------PINMEAVNRLLEEATEDVETLEEETEELVEN 498
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
353-864 |
2.65e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.73 E-value: 2.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 353 QEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALardghDQHVLELEAKMDQLRTMVEAADREkvelLNQLEE 432
Cdd:TIGR00618 337 QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTL-----TQHIHTLQQQKTTLTQKLQSLCKE----LDILQR 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 433 EKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELE-------- 504
Cdd:TIGR00618 408 EQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEqihlqetr 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 505 --KDLALRAQEVAELRRRLESS------------KPPGDVDMSLSLLQEISALQEKLEaiHTDHQGemTSLKEHFGAREE 570
Cdd:TIGR00618 488 kkAVVLARLLELQEEPCPLCGScihpnparqdidNPGPLTRRMQRGEQTYAQLETSEE--DVYHQL--TSERKQRASLKE 563
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 571 AFQKEIKALHTATEK---LSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEEL-KVSFSKGIGTDSAEFAE 646
Cdd:TIGR00618 564 QMQEIQQSFSILTQCdnrSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQdLQDVRLHLQQCSQELAL 643
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 647 LKTQIERLRLDYQHE---IESLQSKQDSERS-----AHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAE--DQHLVEM 716
Cdd:TIGR00618 644 KLTALHALQLTLTQErvrEHALSIRVLPKELlasrqLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEeyDREFNEI 723
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 717 EDTLN----KLQEAEIKANSITKELQEK----------------------ELVLTGLQDSLNQVNQVKETLEKELQTLKE 770
Cdd:TIGR00618 724 ENASSslgsDLAAREDALNQSLKELMHQartvlkarteahfnnneevtaaLQTGAELSHLAAEIQFFNRLREEDTHLLKT 803
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 771 KFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLendIAEIMKMSG 850
Cdd:TIGR00618 804 LEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKI---IQLSDKLNG 880
|
570
....*....|....
gi 1907165170 851 DNSSQLTKMNDELR 864
Cdd:TIGR00618 881 INQIKIQFDGDALI 894
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
641-1211 |
2.90e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 45.28 E-value: 2.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 641 SAEFAELKTQIERLRL---DYQHEIESLQSKQDsERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLD-----SAEDQH 712
Cdd:PRK01156 165 ERNYDKLKDVIDMLRAeisNIDYLEEKLKSSNL-ELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDdynnlKSALNE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 713 LVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQV---------NQVKE--TLEKELQTLKEKFASTSEEAVS 781
Cdd:PRK01156 244 LSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIindpvyknrNYINDyfKYKNDIENKKQILSNIDAEINK 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 782 AQTRMQdTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMND 861
Cdd:PRK01156 324 YHAIIK-KLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEI 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 862 ELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAArkheeekkeleekllelekkMETSYNQCQDLKAKY 941
Cdd:PRK01156 403 DPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNME--------------------MLNGQSVCPVCGTTL 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 942 EKASSETKTKH-EEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELktQADKAKAAQTAEDAMQIMEQMTKEKTETLAS 1020
Cdd:PRK01156 463 GEEKSNHIINHyNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYL--ESEEINKSINEYNKIESARADLEDIKIKINE 540
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1021 LEDTKQTNARLQNELDTLKENNL--KTVEELNKSKELLSVENQKMEEFKKEIET-LKQAAAQKSQQLSALQEENVKLAEE 1097
Cdd:PRK01156 541 LKDKHDKYEEIKNRYKSLKLEDLdsKRTSWLNALAVISLIDIETNRSRSNEIKKqLNDLESRLQEIEIGFPDDKSYIDKS 620
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1098 LGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDAdEEKASLQKSISLTSALLTEKDAELEKLRNEvtvLRGENAT 1177
Cdd:PRK01156 621 IREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQI-AEIDSIIPDLKEITSRINDIEDNLKKSRKA---LDDAKAN 696
|
570 580 590
....*....|....*....|....*....|....
gi 1907165170 1178 AKSLHSVVQTLESDKVKLELKVKNLELQLKENKR 1211
Cdd:PRK01156 697 RARLESTIEILRTRINELSDRINDINETLESMKK 730
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
759-1253 |
2.98e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 2.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 759 ETLEkELQTLKEKFASTSEEAvsAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKL 838
Cdd:COG4913 252 ELLE-PIRELAERYAAARERL--AELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDEL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 839 ENDIAEImkmSGDNSSQLtkmndelrlkERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEE 918
Cdd:COG4913 329 EAQIRGN---GGDRLEQL----------EREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEA 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 919 KLLELEKKMETSYnqcqDLKAKYEKASSETKTKHEEIL----------QNLQKMLADTEDKLKAAQEANR---DLMQDME 985
Cdd:COG4913 396 LEEELEALEEALA----EAEAALRDLRRELRELEAEIAslerrksnipARLLALRDALAEALGLDEAELPfvgELIEVRP 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 986 E-----------LKTQA-------DKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAR-LQNELDTlKENNLKT- 1045
Cdd:COG4913 472 EeerwrgaiervLGGFAltllvppEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDsLAGKLDF-KPHPFRAw 550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1046 -VEELNKSKELLSVENQkmEEFKKE--------------------------------------IETLKQAAAQKSQQLSA 1086
Cdd:COG4913 551 lEAELGRRFDYVCVDSP--EELRRHpraitragqvkgngtrhekddrrrirsryvlgfdnrakLAALEAELAELEEELAE 628
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1087 LQEENVKLAEELGRTRDEVTSHQKLEEersvLNNQLLEMKKRESEFRkDADEEKASLQKSisltSALLTEKDAELEKLRN 1166
Cdd:COG4913 629 AEERLEALEAELDALQERREALQRLAE----YSWDEIDVASAEREIA-ELEAELERLDAS----SDDLAALEEQLEELEA 699
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1167 EVTVLRGEnatakslhsvVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAE---EDERAQESQIDFLNSVIV 1243
Cdd:COG4913 700 ELEELEEE----------LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRallEERFAAALGDAVERELRE 769
|
570
....*....|
gi 1907165170 1244 DLQRKNQDLK 1253
Cdd:COG4913 770 NLEERIDALR 779
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
351-834 |
3.50e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.14 E-value: 3.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 351 ALQEALKEKQQHIEQLLAERDleraEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRtmVEAADREKVELLNQL 430
Cdd:COG4717 75 ELEEELKEAEEKEEEYAELQE----ELEELEEELEELEAELEELREELEKLEKLLQLLPLYQE--LEALEAELAELPERL 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 431 EEEKRKVEDLQFRVEEESITKGDLEtqtKLEHARTKELEQSLLFEKTKADKLQRELEDTRvatvsekSRIMELEKDLALR 510
Cdd:COG4717 149 EELEERLEELRELEEELEELEAELA---ELQEELEELLEQLSLATEEELQDLAEELEELQ-------QRLAELEEELEEA 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 511 AQEVAELRRRLESSKPPGDVDMSLSLLQEISALQEKLEAIHTdHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKEN 590
Cdd:COG4717 219 QEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLA-LLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREK 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 591 ESLRSKLDHANKensdvialwkskLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRlDYQHEIESLQSkqd 670
Cdd:COG4717 298 ASLGKEAEELQA------------LPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQ-ELLREAEELEE--- 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 671 sersahakemetmQAKLMKIIKEKEDSLEAVKArlDSAEDqhLVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDS 750
Cdd:COG4717 362 -------------ELQLEELEQEIAALLAEAGV--EDEEE--LRAALEQAEEYQELKEELEELEEQLEELLGELEELLEA 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 751 LNqvnqvKETLEKELQTLKEKFASTSEEavsaqtrmqdtVNKLHQKEEQfnvLSSELEKLREN--LTDMEAKFKEKDDRE 828
Cdd:COG4717 425 LD-----EEELEEELEELEEELEELEEE-----------LEELREELAE---LEAELEQLEEDgeLAELLQELEELKAEL 485
|
....*.
gi 1907165170 829 DQLVKA 834
Cdd:COG4717 486 RELAEE 491
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
686-1289 |
3.61e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 45.21 E-value: 3.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 686 KLMKIIKEKEDSLEAVKARL-DSAEDQHLVEMEDTLNKLQ-EAEIKANSITKELQEKELVLTGLQDSLNQVnqvkETLEK 763
Cdd:pfam12128 183 KIAKAMHSKEGKFRDVKSMIvAILEDDGVVPPKSRLNRQQvEHWIRDIQAIAGIMKIRPEFTKLQQEFNTL----ESAEL 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 764 ELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQ----KEEQFNVLSSELeklRENLTDMEAKFKEKDDREDQLVKAKEKLE 839
Cdd:pfam12128 259 RLSHLHFGYKSDETLIASRQEERQETSAELNQllrtLDDQWKEKRDEL---NGELSAADAAVAKDRSELEALEDQHGAFL 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 840 NDIAEIMKMSGDN----SSQLTKMNDELRLKERSVEELQLKLTKANENASF-LQKSIGEVTLKAEQSQQQAARKHEEEKK 914
Cdd:pfam12128 336 DADIETAAADQEQlpswQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEqNNRDIAGIKDKLAKIREARDRQLAVAED 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 915 ELEEKLLELEKKMETSYNQCQDLKAKYEKASSETK------TKHEEILQNL---QKMLADTEDKLKAAQEANRDLMQDME 985
Cdd:pfam12128 416 DLQALESELREQLEAGKLEFNEEEYRLKSRLGELKlrlnqaTATPELLLQLenfDERIERAREEQEAANAEVERLQSELR 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 986 ELKTQADKA--------KAAQTAEDAMQIMEQMTKEKTETL-----ASLEDTKQTNARLQNELDTLKENNLKTVEELNKS 1052
Cdd:pfam12128 496 QARKRRDQAsealrqasRRLEERQSALDELELQLFPQAGTLlhflrKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVG 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1053 KEL------LSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQK-LEEERSVLNNQLLEM 1125
Cdd:pfam12128 576 GELnlygvkLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASReETFARTALKNARLDL 655
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1126 KKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKnlELQ 1205
Cdd:pfam12128 656 RRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQ--LAL 733
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1206 LKENKRQLSSSSGNTDAQAEEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMSeaalnGNGEDLNSYDSDDQEKQSKK 1285
Cdd:pfam12128 734 LKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIA-----VRRQEVLRYFDWYQETWLQR 808
|
....
gi 1907165170 1286 KPRL 1289
Cdd:pfam12128 809 RPRL 812
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
355-526 |
3.66e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 44.85 E-value: 3.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 355 ALKEKQQHIEQLLAE---RDLERAEVAKATS-----------HVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAAD 420
Cdd:COG2433 347 AYKNKFERVEKKVPPdvdRDEVKARVIRGLSieealeeliekELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLE 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 421 REKVELLNQLEEEKRKVEDLQFRVEEESItkgdletQTKLEHARTKELEQsllfEKTKADKLQRELEDtrvatvsEKSRI 500
Cdd:COG2433 427 AEVEELEAELEEKDERIERLERELSEARS-------EERREIRKDREISR----LDREIERLERELEE-------ERERI 488
|
170 180
....*....|....*....|....*..
gi 1907165170 501 MELEKDLA-LRAQEVAELRRRLESSKP 526
Cdd:COG2433 489 EELKRKLErLKELWKLEHSGELVPVKV 515
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
569-1013 |
4.01e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 4.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 569 EEAFQKEIKALHTATEKLSKEN----ESLRSKLDHANKENSDVIALWK--SKLETAIASHQQAMEELKVSFSK-GIGTDS 641
Cdd:COG4717 48 LERLEKEADELFKPQGRKPELNlkelKELEEELKEAEEKEEEYAELQEelEELEEELEELEAELEELREELEKlEKLLQL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 642 AEFAELKTQIERLRLDYQHEIESLQSKQDsERSAHAKEMETMQAKlmkiIKEKEDSLEAVKARLDSAEDQHLVEMEDTLN 721
Cdd:COG4717 128 LPLYQELEALEAELAELPERLEELEERLE-ELRELEEELEELEAE----LAELQEELEELLEQLSLATEEELQDLAEELE 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 722 KLQEaeiKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEE--- 798
Cdd:COG4717 203 ELQQ---RLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAgvl 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 799 ---------QFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERS 869
Cdd:COG4717 280 flvlgllalLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 870 VEELQLKLTKANENASFLQ---KSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASS 946
Cdd:COG4717 360 EEELQLEELEQEIAALLAEagvEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEE 439
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 947 ETKTKHEEiLQNLQKMLADTEDKLKAAQEANR--DLMQDMEELKTQ-ADKAKAAQTAEDAMQIMEQMTKE 1013
Cdd:COG4717 440 ELEELEEE-LEELREELAELEAELEQLEEDGElaELLQELEELKAElRELAEEWAALKLALELLEEAREE 508
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
381-740 |
4.45e-04 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 44.46 E-value: 4.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 381 TSHVGEIEQELALARDGHDQ-HVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEeesitkgdlETQTK 459
Cdd:pfam06160 59 TKSLPDIEELLFEAEELNDKyRFKKAKKALDEIEELLDDIEEDIKQILEELDELLESEEKNREEVE---------ELKDK 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 460 LEHARTKELEQSLLFEKTkADKLQRELED-----TRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSkPPGDVDMSL 534
Cdd:pfam06160 130 YRELRKTLLANRFSYGPA-IDELEKQLAEieeefSQFEELTESGDYLEAREVLEKLEEETDALEELMEDI-PPLYEELKT 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 535 SL---LQEISALQEKLEaihtdhqgemtslKEHFGAREEAFQKEIKALHTATEKLSKENESLRskLDHANKENSDV---I 608
Cdd:pfam06160 208 ELpdqLEELKEGYREME-------------EEGYALEHLNVDKEIQQLEEQLEENLALLENLE--LDEAEEALEEIeerI 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 609 ALWKSKLETAIASHQQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQ---HEIESLQSKQdsersAHAKEMETMQA 685
Cdd:pfam06160 273 DQLYDLLEKEVDAKKYVEKNLPE-IEDYLEHAEEQNKELKEELERVQQSYTlneNELERVRGLE-----KQLEELEKRYD 346
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907165170 686 KLMKIIKEKE-------DSLEAVKARLDSAEDQHlVEMEDTLNKLQEAEIKANSITKELQEK 740
Cdd:pfam06160 347 EIVERLEEKEvayselqEELEEILEQLEEIEEEQ-EEFKESLQSLRKDELEAREKLDEFKLE 407
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
967-1139 |
6.04e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.00 E-value: 6.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 967 EDKLKAAQEANRDLMQD----MEELKtqadKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENN 1042
Cdd:PRK12704 30 EAKIKEAEEEAKRILEEakkeAEAIK----KEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1043 LKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKlAEELGRTRDEvtshqkLEEERSVLnnql 1122
Cdd:PRK12704 106 EKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEAK-EILLEKVEEE------ARHEAAVL---- 174
|
170
....*....|....*..
gi 1907165170 1123 leMKKRESEFRKDADEE 1139
Cdd:PRK12704 175 --IKEIEEEAKEEADKK 189
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
399-771 |
6.21e-04 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 43.98 E-value: 6.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 399 DQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFrvEEESITKGDLETQTKLEHARTKELEQSLLFEKTK 478
Cdd:pfam09731 51 LGEDPPLAPKPKTFRPLQPSVVSAVTGESKEPKEEKKQVKIPRQ--SGVSSEVAEEEKEATKDAAEAKAQLPKSEQEKEK 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 479 ADKLQRELEDTRVATVSEKSRIMELEKDLALRAQeVAELRRRLESSKPPGDVDMSLSLLQEISALQEKLEAIHTDHQGEM 558
Cdd:pfam09731 129 ALEEVLKEAISKAESATAVAKEAKDDAIQAVKAH-TDSLKEASDTAEISREKATDSALQKAEALAEKLKEVINLAKQSEE 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 559 TSLKEHFGAREEAFQKEIKALHTATEKLSKEnESLRSKLDHANKENS---------------DVIALWK-------SKLE 616
Cdd:pfam09731 208 EAAPPLLDAAPETPPKLPEHLDNVEEKVEKA-QSLAKLVDQYKELVAserivfqqelvsifpDIIPVLKednllsnDDLN 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 617 TAIAS-------HQQAMEELKVsfskgigtdsAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMK 689
Cdd:pfam09731 287 SLIAHahreidqLSKKLAELKK----------REEKHIERALEKQKEELDKLAEELSARLEEVRAADEAQLRLEFERERE 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 690 IIKEK-EDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTL 768
Cdd:pfam09731 357 EIRESyEEKLRTELERQAEAHEEHLKDVLVEQEIELQREFLQDIKEKVEEERAGRLLKLNELLANLKGLEKATSSHSEVE 436
|
...
gi 1907165170 769 KEK 771
Cdd:pfam09731 437 DEN 439
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
737-1277 |
7.49e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 44.12 E-value: 7.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 737 LQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTD 816
Cdd:PRK01156 164 LERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 817 MEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELqLKLTKANENASFLQKSI-GEVT 895
Cdd:PRK01156 244 LSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDY-FKYKNDIENKKQILSNIdAEIN 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 896 -----------LKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLA 964
Cdd:PRK01156 323 kyhaiikklsvLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEI 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 965 DTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTAEDA----MQIMEQMTK----------EKTETLasLEDTKQTNAR 1030
Cdd:PRK01156 403 DPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDElsrnMEMLNGQSVcpvcgttlgeEKSNHI--INHYNEKKSR 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1031 LQNELDTLKENNLKTVEELNKSKELLS-VENQKMEEFKKEIETLKQAAAQKSQ---QLSALQEENVKLAE--------EL 1098
Cdd:PRK01156 481 LEEKIREIEIEVKDIDEKIVDLKKRKEyLESEEINKSINEYNKIESARADLEDikiKINELKDKHDKYEEiknrykslKL 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1099 GRTRDEVTSHQKLEEERSVLN-----NQLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRG 1173
Cdd:PRK01156 561 EDLDSKRTSWLNALAVISLIDietnrSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQE 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1174 ENATAKSLHSVVQTLESDKVKL---ELKVKNLELQLKENKRQLSSSSGNTDAqAEEDERAQESQIDFLNSVIVDLQRKNQ 1250
Cdd:PRK01156 641 NKILIEKLRGKIDNYKKQIAEIdsiIPDLKEITSRINDIEDNLKKSRKALDD-AKANRARLESTIEILRTRINELSDRIN 719
|
570 580
....*....|....*....|....*....
gi 1907165170 1251 DLKMKVEMMS--EAALNGNGEDLNSYDSD 1277
Cdd:PRK01156 720 DINETLESMKkiKKAIGDLKRLREAFDKS 748
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
724-992 |
8.23e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.85 E-value: 8.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 724 QEAEIKANSITKELQEkelvlTGLQDSLNQVNQVKETLEKELQTLKEKfASTSEEAVSA-QTRmqdtvNKLHQKEEQFNV 802
Cdd:COG3206 148 ELAAAVANALAEAYLE-----QNLELRREEARKALEFLEEQLPELRKE-LEEAEAALEEfRQK-----NGLVDLSEEAKL 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 803 LSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMkmsgdNSSQLTKMNDELRLKERSVEELQLKLTKANE 882
Cdd:COG3206 217 LLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELL-----QSPVIQQLRAQLAELEAELAELSARYTPNHP 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 883 nasflqksigevTLKAEQSQQQAARKheEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTkheeiLQNLQKM 962
Cdd:COG3206 292 ------------DVIALRAQIAALRA--QLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAE-----LPELEAE 352
|
250 260 270
....*....|....*....|....*....|
gi 1907165170 963 LADTEDKLKAAQEANRDLMQDMEELKTQAD 992
Cdd:COG3206 353 LRRLEREVEVARELYESLLQRLEEARLAEA 382
|
|
| CCCAP |
pfam15964 |
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ... |
949-1202 |
8.50e-04 |
|
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 43.74 E-value: 8.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 949 KTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTAEDAMQiMEQMTKEKTETLASLEDTKQTN 1028
Cdd:pfam15964 362 KSELERQKERLEKELASQQEKRAQEKEALRKEMKKEREELGATMLALSQNVAQLEAQ-VEKVTREKNSLVSQLEEAQKQL 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1029 ARLQNELDT--------LKENNLKTVEELNKSKEL-------LSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVK 1093
Cdd:pfam15964 441 ASQEMDVTKvcgemryqLNQTKMKKDEAEKEHREYrtktgrqLEIKDQEIEKLGLELSESKQRLEQAQQDAARAREECLK 520
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1094 LAEELGRTRDEV--TSHQKLEEERSVLNN---QLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEV 1168
Cdd:pfam15964 521 LTELLGESEHQLhlTRLEKESIQQSFSNEakaQALQAQQREQELTQKMQQMEAQHDKTVNEQYSLLTSQNTFIAKLKEEC 600
|
250 260 270
....*....|....*....|....*....|....
gi 1907165170 1169 TVLrgenatAKSLHSVVQTLESDKVKLELKVKNL 1202
Cdd:pfam15964 601 CTL------AKKLEEITQKSRSEVEQLSQEKEYL 628
|
|
| CHASE3 |
COG5278 |
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms]; |
353-784 |
8.51e-04 |
|
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
Pssm-ID: 444089 [Multi-domain] Cd Length: 530 Bit Score: 43.74 E-value: 8.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 353 QEALKEKQQHIEQLLAERDLERAEVAK----ATSHVGEIEQELALARDGHDQHVLELE------AKMDQLRT-MVEAADR 421
Cdd:COG5278 85 RAEIDELLAELRSLTADNPEQQARLDElealIDQWLAELEQVIALRRAGGLEAALALVrsgegkALMDEIRArLLLLALA 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 422 EKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIM 501
Cdd:COG5278 165 LAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALALAL 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 502 ELEKDLALRAQEVAELRRRLESSKPPGDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHT 581
Cdd:COG5278 245 LLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAAAA 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 582 ATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHE 661
Cdd:COG5278 325 LAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAAAAA 404
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 662 IESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKANSITKELQEKE 741
Cdd:COG5278 405 EAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAAAAL 484
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 1907165170 742 LVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQT 784
Cdd:COG5278 485 AEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALAS 527
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
455-677 |
1.06e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.21 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 455 ETQTKLE--HARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKPP----- 527
Cdd:COG4942 24 EAEAELEqlQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEleaqk 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 528 GDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDV 607
Cdd:COG4942 104 EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 608 IALwKSKLETAIASHQQAMEELKVSFSKgigtDSAEFAELKTQIERLrldyQHEIESLQSKQDSERSAHA 677
Cdd:COG4942 184 EEE-RAALEALKAERQKLLARLEKELAE----LAAELAELQQEAEEL----EALIARLEAEAAAAAERTP 244
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
935-1286 |
1.20e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 43.27 E-value: 1.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 935 QDLKAKYEKASSETKTKheeilqNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAkaaqtaedamqimeqmTKEK 1014
Cdd:pfam10174 213 EELHRRNQLQPDPAKTK------ALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLLH----------------TEDR 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1015 TETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKL 1094
Cdd:pfam10174 271 EEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDAL 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1095 A---EELGRTRDEVTSH-QKLEEERSVLNNQLLEMKKresefRKDADEEKAS-LQKSISLTSALLTEKDAELEKLRNEvt 1169
Cdd:pfam10174 351 RlrlEEKESFLNKKTKQlQDLTEEKSTLAGEIRDLKD-----MLDVKERKINvLQKKIENLQEQLRDKDKQLAGLKER-- 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1170 vlrgenatakslhsvVQTLESDKVKLELKVKNLELQLKENKRQLSsssgNTDAQAEEDERAQESQIDflnsvivDLQRKN 1249
Cdd:pfam10174 424 ---------------VKSLQTDSSNTDTALTTLEEALSEKERIIE----RLKEQREREDRERLEELE-------SLKKEN 477
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1907165170 1250 QDLKMKVEMM------SEAALNGNGEDLNSYDSDDQEKQSKKK 1286
Cdd:pfam10174 478 KDLKEKVSALqpelteKESSLIDLKEHASSLASSGLKKDSKLK 520
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1011-1263 |
1.25e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.08 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1011 TKEKTETLASLEDTKQTNARLQNELDTLK--ENNLKTVEELNKSKELL---SVENQKMEEFKK--EIETLKQA------- 1076
Cdd:COG3206 63 PQSSDVLLSGLSSLSASDSPLETQIEILKsrPVLERVVDKLNLDEDPLgeeASREAAIERLRKnlTVEPVKGSnvieisy 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1077 -------AAQKSQQL-SALQEENVKL-AEELGRTRDEvtshqkLEEERSVLNNQLLEMKKRESEFRK-----DADEEKAS 1142
Cdd:COG3206 143 tspdpelAAAVANALaEAYLEQNLELrREEARKALEF------LEEQLPELRKELEEAEAALEEFRQknglvDLSEEAKL 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1143 LQKSISLTSALLTEKDAELEKLRNEVTVLR------GENATAKSLHSVVQTLESDKVKLELKVKNLELQLKEN------- 1209
Cdd:COG3206 217 LLQQLSELESQLAEARAELAEAEARLAALRaqlgsgPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNhpdvial 296
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1907165170 1210 KRQLSSSSGNTDAQAEEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMSEAA 1263
Cdd:COG3206 297 RAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELE 350
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
695-1089 |
1.34e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.40 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 695 EDSLEAVKARLDS-----AEDQHLVEMEDTLNKLQEAEikaNSITKELQEKELVLTGLQDSLNQVNQVkETLEKELQTLK 769
Cdd:COG3096 285 ERALELRRELFGArrqlaEEQYRLVEMARELEELSARE---SDLEQDYQAASDHLNLVQTALRQQEKI-ERYQEDLEELT 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 770 EKFASTSEEAVSAQTRMQDTVNKLHQKEEqfnvlssELEKLRENLTDMEAKFKEKDDRE---DQLVKAKEKLENdIAEIM 846
Cdd:COG3096 361 ERLEEQEEVVEEAAEQLAEAEARLEAAEE-------EVDSLKSQLADYQQALDVQQTRAiqyQQAVQALEKARA-LCGLP 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 847 KMSGDNSSQ-LTKMNDELRLKERSVEELQLKLTKANENAS-------FLQKSIGEV-TLKAEQSQQQAARKHEEEKKELE 917
Cdd:COG3096 433 DLTPENAEDyLAAFRAKEQQATEEVLELEQKLSVADAARRqfekayeLVCKIAGEVeRSQAWQTARELLRRYRSQQALAQ 512
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 918 EKL--LELEKKMETSYNQCQD---LKAKYEKASSETKTKHEEI---LQNLQKMLADTEDKLKAAQEANRDLMQDMEELKT 989
Cdd:COG3096 513 RLQqlRAQLAELEQRLRQQQNaerLLEEFCQRIGQQLDAAEELeelLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRA 592
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 990 Q----ADKAKAAQTAEDAMQIMEQMTKEktetlaSLEDTKQTNARLQNELDTLKennlktveELNKSKELLsveNQKMEE 1065
Cdd:COG3096 593 RikelAARAPAWLAAQDALERLREQSGE------ALADSQEVTAAMQQLLERER--------EATVERDEL---AARKQA 655
|
410 420
....*....|....*....|....
gi 1907165170 1066 FKKEIETLKQAAAQKSQQLSALQE 1089
Cdd:COG3096 656 LESQIERLSQPGGAEDPRLLALAE 679
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
570-876 |
1.61e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 42.64 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 570 EAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAE----FA 645
Cdd:COG5185 242 ESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEeqlaAA 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 646 ELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEdsLEAVKARLDSAEDQHLVEMEDTLNKLQE 725
Cdd:COG5185 322 EAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVE--LSKSSEELDSFKDTIESTKESLDEIPQN 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 726 AEIKANSItkelqekelvLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVnKLHQKEEQFNVLSS 805
Cdd:COG5185 400 QRGYAQEI----------LATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVM-READEESQSRLEEA 468
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907165170 806 ELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLK 876
Cdd:COG5185 469 YDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHIL 539
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
715-908 |
1.70e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.51 E-value: 1.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 715 EMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLH 794
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 795 QKEEQFNVLS--------------------------SELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKM 848
Cdd:COG3883 97 RSGGSVSYLDvllgsesfsdfldrlsalskiadadaDLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 849 SGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARK 908
Cdd:COG3883 177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
956-1133 |
1.85e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 1.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 956 LQNLQKMLADTEDKLKAAQEANR---------DLMQDMEELKTQADKAKAA-QTAEDAMQIMEQMTKEKTETLASLEDT- 1024
Cdd:COG3206 184 LPELRKELEEAEAALEEFRQKNGlvdlseeakLLLQQLSELESQLAEARAElAEAEARLAALRAQLGSGPDALPELLQSp 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1025 ---------KQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLA 1095
Cdd:COG3206 264 viqqlraqlAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARL 343
|
170 180 190
....*....|....*....|....*....|....*...
gi 1907165170 1096 EELGRTRDEVtshQKLEEERSVLNNQLLEMKKRESEFR 1133
Cdd:COG3206 344 AELPELEAEL---RRLEREVEVARELYESLLQRLEEAR 378
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
723-864 |
2.18e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.46 E-value: 2.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 723 LQEAEIKANSITKE--LQEKELVLtglqdslnqvnQVKETLEKELQTLKEKFastseeavsaqtrmQDTVNKLHQKEEQF 800
Cdd:PRK12704 44 LEEAKKEAEAIKKEalLEAKEEIH-----------KLRNEFEKELRERRNEL--------------QKLEKRLLQKEENL 98
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907165170 801 NVLSSELEKLRENLtdmEAKFKEKDDREDQLVKAKEKLENDIAE-------IMKMSGDNSSQ--LTKMNDELR 864
Cdd:PRK12704 99 DRKLELLEKREEEL---EKKEKELEQKQQELEKKEEELEELIEEqlqelerISGLTAEEAKEilLEKVEEEAR 168
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
374-580 |
2.35e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 42.64 E-value: 2.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 374 RAEVAKATSHVGEIEQELALARDGHDQHvlelEAKMDQLRTMV-----EAADREKVELLNQLEEEKRKVEDLQFRVEEES 448
Cdd:PRK04863 448 QAKEQEATEELLSLEQKLSVAQAAHSQF----EQAYQLVRKIAgevsrSEAWDVARELLRRLREQRHLAEQLQQLRMRLS 523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 449 ITKGDLETQTKLEHARtKELEQSLLFEKTKADKLQRELED--TRVATVSE-KSRIMELEKDLALRAQEVAELRRRLESSK 525
Cdd:PRK04863 524 ELEQRLRQQQRAERLL-AEFCKRLGKNLDDEDELEQLQEEleARLESLSEsVSEARERRMALRQQLEQLQARIQRLAARA 602
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907165170 526 PPG-DVDMSLSLLQEISALQ-------EKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALH 580
Cdd:PRK04863 603 PAWlAAQDALARLREQSGEEfedsqdvTEYMQQLLERERELTVERDELAARKQALDEEIERLS 665
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
932-1252 |
2.82e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.93 E-value: 2.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 932 NQCQDLKAKYEKASSETKTKhEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKaaqtaedamQIMEQMT 1011
Cdd:TIGR04523 33 TEEKQLEKKLKTIKNELKNK-EKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNK---------DKINKLN 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1012 KEKTETLASLEDTKQTNARLQNELDTLK-------ENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQL 1084
Cdd:TIGR04523 103 SDLSKINSEIKNDKEQKNKLEVELNKLEkqkkenkKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEK 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1085 SALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISLTSA-------LLTEK 1157
Cdd:TIGR04523 183 LNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNtqtqlnqLKDEQ 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1158 DAELEKLRNEVTVLRGENATAKSLHSVVQTLESD-----KVKLELKVKNLELQLKENKRQLSsssgntdaQAEEDERAQE 1232
Cdd:TIGR04523 263 NKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEisdlnNQKEQDWNKELKSELKNQEKKLE--------EIQNQISQNN 334
|
330 340
....*....|....*....|
gi 1907165170 1233 SQIDFLNSVIVDLQRKNQDL 1252
Cdd:TIGR04523 335 KIISQLNEQISQLKKELTNS 354
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
356-525 |
3.15e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.03 E-value: 3.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 356 LKEKQQHIEQLLAE---------RDLERAEVAKATSHvGEIEQELALARDghdQHVLELEAKMDQLRTMVEAaDREKVEL 426
Cdd:pfam17380 355 QEERKRELERIRQEeiameisrmRELERLQMERQQKN-ERVRQELEAARK---VKILEEERQRKIQQQKVEM-EQIRAEQ 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 427 LNQLEEEKRKVEDLQFRvEEESITKGDLETQTKLEHARTKELEQ---SLLFEKTKADK----------LQRELEDTRVAT 493
Cdd:pfam17380 430 EEARQREVRRLEEERAR-EMERVRLEEQERQQQVERLRQQEEERkrkKLELEKEKRDRkraeeqrrkiLEKELEERKQAM 508
|
170 180 190
....*....|....*....|....*....|..
gi 1907165170 494 VSEKSRIMELEKDLALRAQEVAELRRRLESSK 525
Cdd:pfam17380 509 IEEERKRKLLEKEMEERQKAIYEEERRREAEE 540
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
865-1098 |
3.26e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 41.82 E-value: 3.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 865 LKERSVEELQLKLTKAN-ENASFLQKSIGEVTLKAEQSQQQAARkheeekkeleeklleLEKKMETSYNQCQDLKAKYEK 943
Cdd:PRK11281 48 LNKQKLLEAEDKLVQQDlEQTLALLDKIDRQKEETEQLKQQLAQ---------------APAKLRQAQAELEALKDDNDE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 944 ASSETKTKHEeiLQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTAedAMQIMEQMTKEKTETLASLED 1023
Cdd:PRK11281 113 ETRETLSTLS--LRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYA--NSQRLQQIRNLLKGGKVGGKA 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1024 TKQT-----NARL-----QNELD-TLKENNLKTVEELNKSKELLSVENQKMEEF----------KKEIETLKQAAAQKSQ 1082
Cdd:PRK11281 189 LRPSqrvllQAEQallnaQNDLQrKSLEGNTQLQDLLQKQRDYLTARIQRLEHQlqllqeainsKRLTLSEKTVQEAQSQ 268
|
250
....*....|....*.
gi 1907165170 1083 QLSALQEENVKLAEEL 1098
Cdd:PRK11281 269 DEAARIQANPLVAQEL 284
|
|
| HAP1_N |
pfam04849 |
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ... |
1082-1248 |
3.68e-03 |
|
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.
Pssm-ID: 461455 [Multi-domain] Cd Length: 309 Bit Score: 41.16 E-value: 3.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1082 QQLSALQEENVKLAEELGRTRDEVT--SHQ--KLEEERSVLNNQLLEMKKRESE-FRKDADEEKASLQKSISLTsaLLTE 1156
Cdd:pfam04849 94 KQNSVLTERNEALEEQLGSAREEILqlRHElsKKDDLLQIYSNDAEESETESSCsTPLRRNESFSSLHGCVQLD--ALQE 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1157 KDAELE----KLRNEVTVLRGENATaksLHSVVQTLESDKVKlelkvknlelQLKENKRQLSSSSGNTDAQAEEDERAQE 1232
Cdd:pfam04849 172 KLRGLEeenlKLRSEASHLKTETDT---YEEKEQQLMSDCVE----------QLSEANQQMAELSEELARKMEENLRQQE 238
|
170
....*....|....*.
gi 1907165170 1233 sQIDFLNSVIVDLQRK 1248
Cdd:pfam04849 239 -EITSLLAQIVDLQHK 253
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
404-598 |
4.84e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.29 E-value: 4.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 404 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKT--KADK 481
Cdd:COG1579 14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNnkEYEA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 482 LQRELEdtrvatvSEKSRIMELEKDLalraqevaelrrrlesskppgdvdmsLSLLQEISALQEKLEAIhtdhQGEMTSL 561
Cdd:COG1579 94 LQKEIE-------SLKRRISDLEDEI--------------------------LELMERIEELEEELAEL----EAELAEL 136
|
170 180 190
....*....|....*....|....*....|....*..
gi 1907165170 562 KEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLD 598
Cdd:COG1579 137 EAELEEKKAELDEELAELEAELEELEAEREELAAKIP 173
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
969-1286 |
5.06e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 41.38 E-value: 5.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 969 KLKAAQEANRDLMQDMEELKTQADKAKaaqtaEDAMQIMEQMTKEKTETLASLEDTKQTNA----RLQNELDTLKENNLK 1044
Cdd:PLN03229 423 KREAVKTPVRELEGEVEKLKEQILKAK-----ESSSKPSELALNEMIEKLKKEIDLEYTEAviamGLQERLENLREEFSK 497
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1045 TVEELNKSKELLSVENQK-MEEFKKEI------ETLKQA-----AAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLE 1112
Cdd:PLN03229 498 ANSQDQLMHPVLMEKIEKlKDEFNKRLsrapnyLSLKYKldmlnEFSRAKALSEKKSKAEKLKAEINKKFKEVMDRPEIK 577
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1113 EERSVLNNQLLEMK-KRESEFRKDADEEKASLQKSISLTSA-LLTEKDAELEKLRNEvTVLRGENATAKSLHSVVQTLES 1190
Cdd:PLN03229 578 EKMEALKAEVASSGaSSGDELDDDLKEKVEKMKKEIELELAgVLKSMGLEVIGVTKK-NKDTAEQTPPPNLQEKIESLNE 656
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1191 D---KVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQIDFLNSVIVD---LQRKNQDLKMKVEMMSEAAL 1264
Cdd:PLN03229 657 EinkKIERVIRSSDLKSKIELLKLEVAKASKTPDVTEKEKIEALEQQIKQKIAEALNsseLKEKFEELEAELAAARETAA 736
|
330 340
....*....|....*....|..
gi 1907165170 1265 NGNGEDLNSYDSDDQEKQSKKK 1286
Cdd:PLN03229 737 ESNGSLKNDDDKEEDSKEDGSR 758
|
|
| Filament |
pfam00038 |
Intermediate filament protein; |
535-873 |
5.22e-03 |
|
Intermediate filament protein;
Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 40.67 E-value: 5.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 535 SLLQEISALQEKLEAIHTDHQGEMTSLKEHFgareeafQKEIKALHTATEKLSKENESLRSKLDHANKENSDVialwKSK 614
Cdd:pfam00038 22 FLEQQNKLLETKISELRQKKGAEPSRLYSLY-------EKEIEDLRRQLDTLTVERARLQLELDNLRLAAEDF----RQK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 615 LETAIAsHQQAMEelkvsfskgigtdsAEFAELKTQIERL---RLDYQHEIESLQSKQDSERSAHAKEMETMQAKLmkii 691
Cdd:pfam00038 91 YEDELN-LRTSAE--------------NDLVGLRKDLDEAtlaRVDLEAKIESLKEELAFLKKNHEEEVRELQAQV---- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 692 kekedsleavkarldsAEDQHLVEMEDTLNklqeaeIKANSITKELQekelvltglQDSLNQVNQVKETLEKELQTlkeK 771
Cdd:pfam00038 152 ----------------SDTQVNVEMDAARK------LDLTSALAEIR---------AQYEEIAAKNREEAEEWYQS---K 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 772 FASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRenltdmeakfKEKDDREDQLVKAKEKLENDIAEIMKMSGD 851
Cdd:pfam00038 198 LEELQQAAARNGDALRSAKEEITELRRTIQSLEIELQSLK----------KQKASLERQLAETEERYELQLADYQELISE 267
|
330 340
....*....|....*....|..
gi 1907165170 852 NSSQLTKMNDELRLKERSVEEL 873
Cdd:pfam00038 268 LEAELQETRQEMARQLREYQEL 289
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1013-1236 |
5.46e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.58 E-value: 5.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1013 EKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQK----SQQLSALQ 1088
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERreelGERARALY 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1089 E--------ENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSIsltsALLTEKDAE 1160
Cdd:COG3883 97 RsggsvsylDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALK----AELEAAKAE 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907165170 1161 LEKLRNEVTVLrgenatakslhsvVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQID 1236
Cdd:COG3883 173 LEAQQAEQEAL-------------LAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
586-809 |
5.61e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 41.15 E-value: 5.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 586 LSKENESLRSKLDHANkENSDVIALWKSKLETAIASHQQAMEELKVSfskgigtDSAEFAELKTQIERLR---LDYQHEI 662
Cdd:PHA02562 165 LSEMDKLNKDKIRELN-QQIQTLDMKIDHIQQQIKTYNKNIEEQRKK-------NGENIARKQNKYDELVeeaKTIKAEI 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 663 ESLQ------SKQDSERSAHAKEMETMQAKL-------MKIIKEKED---------SLEAVKARLDSAEDQhLVEMEDTL 720
Cdd:PHA02562 237 EELTdellnlVMDIEDPSAALNKLNTAAAKIkskieqfQKVIKMYEKggvcptctqQISEGPDRITKIKDK-LKELQHSL 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 721 NKLQEAEIKANSITKELQEKELVLTGLQDSLNQ--------VNQVKEtLEKELQTLKEKFASTSEEAVSAQTRMQDTVNK 792
Cdd:PHA02562 316 EKLDTAIDELEEIMDEFNEQSKKLLELKNKISTnkqslitlVDKAKK-VKAAIEELQAEFVDNAEELAKLQDELDKIVKT 394
|
250
....*....|....*....
gi 1907165170 793 L--HQKEEQFNVLSSELEK 809
Cdd:PHA02562 395 KseLVKEKYHRGIVTDLLK 413
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
747-1103 |
5.79e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.03 E-value: 5.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 747 LQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLhqkEEQFNVLSSELEKLRENLTDMEAKFKEKDD 826
Cdd:pfam07888 32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRREL---ESRVAELKEELRQSREKHEELEEKYKELSA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 827 REDQLVKAKEKLendiaeiMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQqqaa 906
Cdd:pfam07888 109 SSEELSEEKDAL-------LAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQ---- 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 907 rkheeekkeleeklleleKKMETSYNQCQDLKAKYEKASSETKTKHEEILQnLQKMLADTEDKLKAAQEANRDLMQDMEE 986
Cdd:pfam07888 178 ------------------AKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQ-LQDTITTLTQKLTTAHRKEAENEALLEE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 987 LKTQADKAKAAQTAEDAMqimeqmtKEKTETLASLEDTKQTN---ARLQNELDTLK--ENNLKTVEELNKSKELLSVENQ 1061
Cdd:pfam07888 239 LRSLQERLNASERKVEGL-------GEELSSMAAQRDRTQAElhqARLQAAQLTLQlaDASLALREGRARWAQERETLQQ 311
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1907165170 1062 KMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRD 1103
Cdd:pfam07888 312 SAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELGREKD 353
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
978-1155 |
5.89e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 40.85 E-value: 5.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 978 RDLMQDMEELKTQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLS 1057
Cdd:PRK12705 29 QRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEEQLDARAEKLDNLENQLE 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1058 VENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKlAEELGRTRDEvtshqkLEEERSVLNNQLLEMKKRESEfRKDAD 1137
Cdd:PRK12705 109 EREKALSARELELEELEKQLDNELYRVAGLTPEQAR-KLLLKLLDAE------LEEEKAQRVKKIEEEADLEAE-RKAQN 180
|
170
....*....|....*...
gi 1907165170 1138 EEKASLQKSISLTSALLT 1155
Cdd:PRK12705 181 ILAQAMQRIASETASDLS 198
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
926-1213 |
6.08e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 40.88 E-value: 6.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 926 KMETSYNQCQdlkakYEKASSETKTKHeeiLQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKaaQTAEDAMQ 1005
Cdd:pfam05557 35 KASALKRQLD-----RESDRNQELQKR---IRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKE--SQLADARE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1006 IMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENN----------LKTVEELNKSKELLSVENQKMEEFKKEIetlkQ 1075
Cdd:pfam05557 105 VISCLKNELSELRRQIQRAELELQSTNSELEELQERLdllkakaseaEQLRQNLEKQQSSLAEAEQRIKELEFEI----Q 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1076 AAAQKSQQLSALQEENVKLAE---ELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKdADEEKASLQKSISLTSA 1152
Cdd:pfam05557 181 SQEQDSEIVKNSKSELARIPElekELERLREHNKHLNENIENKLLLKEEVEDLKRKLEREEK-YREEAATLELEKEKLEQ 259
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907165170 1153 LLTE-----KDAEL-----EKLRNEVTVLRGENATAK----SLHSVVQTLESDKVKLELKVKNLELQLKENKRQL 1213
Cdd:pfam05557 260 ELQSwvklaQDTGLnlrspEDLSRRIEQLQQREIVLKeensSLTSSARQLEKARRELEQELAQYLKKIEDLNKKL 334
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
931-1286 |
6.56e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 41.22 E-value: 6.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 931 YNQCQDLKA---KYEKASSETKTKHEEILQNlQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKA--AQTAEDAMQ 1005
Cdd:COG5022 836 EEVEFSLKAevlIQKFGRSLKAKKRFSLLKK-ETIYLQSAQRVELAERQLQELKIDVKSISSLKLVNLEleSEIIELKKS 914
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1006 IMEQMTKE---KTETLASLEDTKQTNarlqnELDTLKENNLKTVEELNKskelLSVENQKMEEFKKEIE-TLKQAAAQKS 1081
Cdd:COG5022 915 LSSDLIENlefKTELIARLKKLLNNI-----DLEEGPSIEYVKLPELNK----LHEVESKLKETSEEYEdLLKKSTILVR 985
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1082 QQLSALqEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKrESEFRKDADEEKASLQKSISLTSALLtekdAEL 1161
Cdd:COG5022 986 EGNKAN-SELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQS-ASKIISSESTELSILKPLQKLKGLLL----LEN 1059
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1162 EKLRNEVTVLRGENATAKSLHSVVQTLESDKVKL-ELKVKNLELqlkeNKRQLSSSSGNTDAQAEEDERAQESQI--DFL 1238
Cdd:COG5022 1060 NQLQARYKALKLRRENSLLDDKQLYQLESTENLLkTINVKDLEV----TNRNLVKPANVLQFIVAQMIKLNLLQEisKFL 1135
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1907165170 1239 NSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQSKKK 1286
Cdd:COG5022 1136 SQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLY 1183
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
351-764 |
6.81e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 40.65 E-value: 6.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDqhvlELEAKMDQLRTMVEAADREKVELLNQL 430
Cdd:pfam07888 49 AQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHE----ELEEKYKELSASSEELSEEKDALLAQR 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 431 EEEKRKVEDLQFRVEEESITKGDLETQTKLEHARTKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALR 510
Cdd:pfam07888 125 AAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQR 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 511 AQEVAELRrrlesskppgdvdmslsllQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKAlhtatEKLSKEN 590
Cdd:pfam07888 205 DTQVLQLQ-------------------DTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKV-----EGLGEEL 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 591 ESLRSKLDHANKEnsdviaLWKSKLETAIASHQqameelkvsfskgigtdsaeFAELKTQIERLRLDYQHEIESLQSKQD 670
Cdd:pfam07888 261 SSMAAQRDRTQAE------LHQARLQAAQLTLQ--------------------LADASLALREGRARWAQERETLQQSAE 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 671 SERSAHAKEMETMQaKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQeaEIKAnSITKELQEKELVLTGLQDS 750
Cdd:pfam07888 315 ADKDRIEKLSAELQ-RLEERLQEERMEREKLEVELGREKDCNRVQLSESRRELQ--ELKA-SLRVAQKEKEQLQAEKQEL 390
|
410
....*....|....
gi 1907165170 751 LNQVNQVKETLEKE 764
Cdd:pfam07888 391 LEYIRQLEQRLETV 404
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
484-876 |
7.25e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.52 E-value: 7.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 484 RELEDTRVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKppgdvdmslSLLQEISALQEKLEAIHTDHQGEMTslKE 563
Cdd:COG4717 74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELR---------EELEKLEKLLQLLPLYQELEALEAE--LA 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 564 HFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKVSfskgigtdSAE 643
Cdd:COG4717 143 ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAEL--------EEE 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 644 FAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEM-------------------------------ETMQAKLMKIIK 692
Cdd:COG4717 215 LEEAQEELEELEEELEQLENELEAAALEERLKEARLLlliaaallallglggsllsliltiagvlflvLGLLALLFLLLA 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 693 EKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVKETL-----EKELQT 767
Cdd:COG4717 295 REKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELqleelEQEIAA 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 768 LKEKFASTSEEAVSAQtrmQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKD--DREDQLVKAKEKLENDIAEI 845
Cdd:COG4717 375 LLAEAGVEDEEELRAA---LEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEleEELEELEEELEELEEELEEL 451
|
410 420 430
....*....|....*....|....*....|.
gi 1907165170 846 MKMSGDNSSQLTKMNDELRLKERSVEELQLK 876
Cdd:COG4717 452 REELAELEAELEQLEEDGELAELLQELEELK 482
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
956-1118 |
7.58e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.52 E-value: 7.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 956 LQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQT-AEDAMQIMEQMTKEKTETLASLEDTKQTNArLQNE 1034
Cdd:COG1579 19 LDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKrLELEIEEVEARIKKYEEQLGNVRNNKEYEA-LQKE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1035 LDTLKennlKTVEELNksKELLSVENQKmEEFKKEIETLKQAAAQKSQQLSALQEEnvkLAEELGRTRDEVtshQKLEEE 1114
Cdd:COG1579 98 IESLK----RRISDLE--DEILELMERI-EELEEELAELEAELAELEAELEEKKAE---LDEELAELEAEL---EELEAE 164
|
....
gi 1907165170 1115 RSVL 1118
Cdd:COG1579 165 REEL 168
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
684-1198 |
7.84e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 40.49 E-value: 7.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 684 QAKLMKIIKEKEDSLEAVKARLDSAED-----QHLVEMEDTLNKLQEAEIKANSITKELQEKELVLTGLQDSLNQVNQVK 758
Cdd:pfam05557 16 NEKKQMELEHKRARIELEKKASALKRQldresDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEK 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 759 ETLEKELQTLKekfASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKL 838
Cdd:pfam05557 96 ESQLADAREVI---SCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEAEQRI 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 839 ENDIAEIMKMSgDNSSQLTKMNDELRlkerSVEELQLKLTKANENASFLQKSIGEVTL-------------KAEQSQQQA 905
Cdd:pfam05557 173 KELEFEIQSQE-QDSEIVKNSKSELA----RIPELEKELERLREHNKHLNENIENKLLlkeevedlkrkleREEKYREEA 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 906 ARKHEEEKKELEEKLLELEKKMETSYN--------------QCQDLKAKYEKASSETKTKHEEILQ--------NLQKML 963
Cdd:pfam05557 248 ATLELEKEKLEQELQSWVKLAQDTGLNlrspedlsrrieqlQQREIVLKEENSSLTSSARQLEKARreleqelaQYLKKI 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 964 ADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTkqtnarlqneLDTLKENNL 1043
Cdd:pfam05557 328 EDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELTMSNYSPQLLERIEEAEDM----------TQKMQAHNE 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1044 KTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEElgrtrdevtsHQKLEEERSVLNNQLL 1123
Cdd:pfam05557 398 EMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPSYSKEEVDSLRRKLE----------TLELERQRLREQKNEL 467
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907165170 1124 EMKKRESEFRKDADEEKAS-LQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELK 1198
Cdd:pfam05557 468 EMELERRCLQGDYDPKKTKvLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMNFK 543
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
946-1085 |
8.17e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 39.95 E-value: 8.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 946 SETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELK-----TQADKAKAAQTAEDAMQIMEQMTKEKTETLAS 1020
Cdd:PRK09039 45 SREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRaslsaAEAERSRLQALLAELAGAGAAAEGRAGELAQE 124
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907165170 1021 LEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQ----AAAQKSQQLS 1085
Cdd:PRK09039 125 LDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEKRDRESQAKIADLGRrlnvALAQRVQELN 193
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1012-1168 |
8.30e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.52 E-value: 8.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1012 KEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKeietlKQAAAQKSQQLSALQEEN 1091
Cdd:COG1579 24 HRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEE-----QLGNVRNNKEYEALQKEI 98
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907165170 1092 VKLAEELGRTRDEVtshQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEV 1168
Cdd:COG1579 99 ESLKRRISDLEDEI---LELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKI 172
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
793-1146 |
8.80e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 40.72 E-value: 8.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 793 LHQKEEQFNVLSSELEKLR--ENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQ-----LTKMNDELRL 865
Cdd:TIGR00618 158 LKAKSKEKKELLMNLFPLDqyTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQvlekeLKHLREALQQ 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 866 KERSVEELQLKLTKANEnASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKAS 945
Cdd:TIGR00618 238 TQQSHAYLTQKREAQEE-QLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTEL 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 946 SETKTKHEEILQNLQKMLADTEDkLKAAQEANRDLMQDMEELKTQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTK 1025
Cdd:TIGR00618 317 QSKMRSRAKLLMKRAAHVKQQSS-IEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKL 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1026 QTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSA----LQEENVKLAEELGRT 1101
Cdd:TIGR00618 396 QSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLekihLQESAQSLKEREQQL 475
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1907165170 1102 RDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKS 1146
Cdd:TIGR00618 476 QTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDI 520
|
|
| Borrelia_P83 |
pfam05262 |
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins. |
953-1117 |
8.99e-03 |
|
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
Pssm-ID: 114011 [Multi-domain] Cd Length: 489 Bit Score: 40.37 E-value: 8.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 953 EEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKA----KAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTN 1028
Cdd:pfam05262 188 EDNEKGVNFRRDMTDLKERESQEDAKRAQQLKEELDKKQIDAdkaqQKADFAQDNADKQRDEVRQKQQEAKNLPKPADTS 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907165170 1029 ARLQNEldTLKENNLKTVEELNK-----SKELLSVENQKMEEFKKEIETLKQAAAQKSQQlsaLQEENVKLAEELGRTRD 1103
Cdd:pfam05262 268 SPKEDK--QVAENQKREIEKAQIeikknDEEALKAKDHKAFDLKQESKASEKEAEDKELE---AQKKREPVAEDLQKTKP 342
|
170
....*....|....
gi 1907165170 1104 EVTSHQKLEEERSV 1117
Cdd:pfam05262 343 QVEAQPTSLNEDAI 356
|
|
| |
