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Conserved domains on  [gi|1907100623|ref|XP_036014453|]
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zinc finger MYM-type protein 5 isoform X1 [Mus musculus]

Protein Classification

zf-FCS and ZnF_TTF domain-containing protein( domain architecture ID 10534321)

zf-FCS and ZnF_TTF domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZnF_TTF super family cl02692
zinc finger in transposases and transcription factors;
528-603 1.44e-06

zinc finger in transposases and transcription factors;


The actual alignment was detected with superfamily member smart00597:

Pssm-ID: 214739  Cd Length: 91  Bit Score: 46.71  E-value: 1.44e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907100623  528 YYTRILPNGEKGTRPWLLYSASKDSVFCLYCRLF---GEGKNQLRNENGCKDWHHLSHLLSKHDESEMHINNSVKYSKL 603
Cdd:smart00597   1 KPRRFQKSWFHQFPDWLEYSVEKDAAFCKYCYLFrpgRDGGSDLFVTEGFCSWKKERIRLKQHEVSKRHRNARLCVNLM 79
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 343-381 1.53e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.36  E-value: 1.53e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1907100623 343 LIMNCCEQCSKYMP-KSTGHSILITGQQKRFCCQNCADEY 381
Cdd:pfam06467   1 LVKATCWFCKKLIKnKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 209-245 8.78e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 8.78e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1907100623 209 VKVTCANCKKPLQKGQTAY--QRKGSAHLFCSTTCLSSF 245
Cdd:pfam06467   2 VKATCWFCKKLIKNKPTVIvlQNDGSVGQFCSQSCLDSY 40
 
Name Accession Description Interval E-value
ZnF_TTF smart00597
zinc finger in transposases and transcription factors;
528-603 1.44e-06

zinc finger in transposases and transcription factors;


Pssm-ID: 214739  Cd Length: 91  Bit Score: 46.71  E-value: 1.44e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907100623  528 YYTRILPNGEKGTRPWLLYSASKDSVFCLYCRLF---GEGKNQLRNENGCKDWHHLSHLLSKHDESEMHINNSVKYSKL 603
Cdd:smart00597   1 KPRRFQKSWFHQFPDWLEYSVEKDAAFCKYCYLFrpgRDGGSDLFVTEGFCSWKKERIRLKQHEVSKRHRNARLCVNLM 79
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 343-381 1.53e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.36  E-value: 1.53e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1907100623 343 LIMNCCEQCSKYMP-KSTGHSILITGQQKRFCCQNCADEY 381
Cdd:pfam06467   1 LVKATCWFCKKLIKnKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 209-245 8.78e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 8.78e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1907100623 209 VKVTCANCKKPLQKGQTAY--QRKGSAHLFCSTTCLSSF 245
Cdd:pfam06467   2 VKATCWFCKKLIKNKPTVIvlQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
348-385 1.07e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.67  E-value: 1.07e-04
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1907100623  348 CEQCSKYM-PKSTGHSILITGQQKRFCCQNCADEYKEIM 385
Cdd:smart00746   1 CSFCGKDIyNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
213-249 1.29e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.67  E-value: 1.29e-04
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1907100623  213 CANCKKPLQKGQTA--YQRKGSAHLFCSTTCLSSFSHKR 249
Cdd:smart00746   1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
 
Name Accession Description Interval E-value
ZnF_TTF smart00597
zinc finger in transposases and transcription factors;
528-603 1.44e-06

zinc finger in transposases and transcription factors;


Pssm-ID: 214739  Cd Length: 91  Bit Score: 46.71  E-value: 1.44e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907100623  528 YYTRILPNGEKGTRPWLLYSASKDSVFCLYCRLF---GEGKNQLRNENGCKDWHHLSHLLSKHDESEMHINNSVKYSKL 603
Cdd:smart00597   1 KPRRFQKSWFHQFPDWLEYSVEKDAAFCKYCYLFrpgRDGGSDLFVTEGFCSWKKERIRLKQHEVSKRHRNARLCVNLM 79
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 343-381 1.53e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.36  E-value: 1.53e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1907100623 343 LIMNCCEQCSKYMP-KSTGHSILITGQQKRFCCQNCADEY 381
Cdd:pfam06467   1 LVKATCWFCKKLIKnKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 209-245 8.78e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 8.78e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1907100623 209 VKVTCANCKKPLQKGQTAY--QRKGSAHLFCSTTCLSSF 245
Cdd:pfam06467   2 VKATCWFCKKLIKNKPTVIvlQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
348-385 1.07e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.67  E-value: 1.07e-04
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1907100623  348 CEQCSKYM-PKSTGHSILITGQQKRFCCQNCADEYKEIM 385
Cdd:smart00746   1 CSFCGKDIyNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
213-249 1.29e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.67  E-value: 1.29e-04
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 1907100623  213 CANCKKPLQKGQTA--YQRKGSAHLFCSTTCLSSFSHKR 249
Cdd:smart00746   1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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