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Conserved domains on  [gi|1907083455|ref|XP_036012946|]
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dynein regulatory complex subunit 3 isoform X1 [Mus musculus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 1903219)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PPP1R42 super family cl42388
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 53-200 7.70e-20

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


The actual alignment was detected with superfamily member cd21340:

Pssm-ID: 455733 [Multi-domain]  Cd Length: 220  Bit Score: 88.30  E-value: 7.70e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455  53 QNILRIDNLWQFENLKKLQLNNNIIERIEGLTNLIHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSNNRISKVDSLDALVK 132
Cdd:cd21340    12 KNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISVVEGLENLTN 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455 133 ------------------------------LQVLSLGNNQISNMMNIIYLRR-----------------------FPCLR 159
Cdd:cd21340    92 leelhienqrlppgekltfdprslaalsnsLRVLNISGNNIDSLEPLAPLRNleqldasnnqisdleelldllssWPSLR 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1907083455 160 TLSLAGNPVSEAEEYKMFIYAYLSDLVYLDFRRVDEQMREM 200
Cdd:cd21340   172 ELDLTGNPVCKKPKYRDKIILASKSLEVLDGKEITDTERQF 212
 
Name Accession Description Interval E-value
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 53-200 7.70e-20

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 88.30  E-value: 7.70e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455  53 QNILRIDNLWQFENLKKLQLNNNIIERIEGLTNLIHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSNNRISKVDSLDALVK 132
Cdd:cd21340    12 KNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISVVEGLENLTN 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455 133 ------------------------------LQVLSLGNNQISNMMNIIYLRR-----------------------FPCLR 159
Cdd:cd21340    92 leelhienqrlppgekltfdprslaalsnsLRVLNISGNNIDSLEPLAPLRNleqldasnnqisdleelldllssWPSLR 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1907083455 160 TLSLAGNPVSEAEEYKMFIYAYLSDLVYLDFRRVDEQMREM 200
Cdd:cd21340   172 ELDLTGNPVCKKPKYRDKIILASKSLEVLDGKEITDTERQF 212
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
42-192 4.16e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 74.20  E-value: 4.16e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455  42 FKDVLSLQLDFQNILRI-DNLWQFENLKKLQLNNNIIERI-EGLTNLIHLVWLDLSFNNIEAI-EGLDTLVNLEDLSLSN 118
Cdd:COG4886   112 LTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSN 191

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907083455 119 NRISKV-DSLDALVKLQVLSLGNNQISNMMNIiyLRRFPCLRTLSLAGNPVSEAEEykmfiYAYLSDLVYLDFRR 192
Cdd:COG4886   192 NQITDLpEPLGNLTNLEELDLSGNQLTDLPEP--LANLTNLETLDLSNNQLTDLPE-----LGNLTNLEELDLSN 259
LRR_9 pfam14580
Leucine-rich repeat;
68-202 7.07e-12

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 64.01  E-value: 7.07e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455  68 KKLQLNNNIIERIEGL-TNLIHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSNNRISKV-DSLD-ALVKLQVLSLGNNQIS 144
Cdd:pfam14580  22 RELDLRGYKIPIIENLgATLDQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRIgEGLGeALPNLTELILTNNNLQ 101

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907083455 145 NMMNIIYLRRFPCLRTLSLAGNPVSEAEEYKMFIYAYLSDLVYLDFRRVDEQMREMAK 202
Cdd:pfam14580 102 ELGDLDPLASLKKLTFLSLLRNPVTNKPHYRLYVIYKVPQLRLLDFRKVKQKERQAAE 159
 
Name Accession Description Interval E-value
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 53-200 7.70e-20

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 88.30  E-value: 7.70e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455  53 QNILRIDNLWQFENLKKLQLNNNIIERIEGLTNLIHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSNNRISKVDSLDALVK 132
Cdd:cd21340    12 KNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISVVEGLENLTN 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455 133 ------------------------------LQVLSLGNNQISNMMNIIYLRR-----------------------FPCLR 159
Cdd:cd21340    92 leelhienqrlppgekltfdprslaalsnsLRVLNISGNNIDSLEPLAPLRNleqldasnnqisdleelldllssWPSLR 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1907083455 160 TLSLAGNPVSEAEEYKMFIYAYLSDLVYLDFRRVDEQMREM 200
Cdd:cd21340   172 ELDLTGNPVCKKPKYRDKIILASKSLEVLDGKEITDTERQF 212
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
42-192 4.16e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 74.20  E-value: 4.16e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455  42 FKDVLSLQLDFQNILRI-DNLWQFENLKKLQLNNNIIERI-EGLTNLIHLVWLDLSFNNIEAI-EGLDTLVNLEDLSLSN 118
Cdd:COG4886   112 LTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDLSNNQLTDLpEELGNLTNLKELDLSN 191

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907083455 119 NRISKV-DSLDALVKLQVLSLGNNQISNMMNIiyLRRFPCLRTLSLAGNPVSEAEEykmfiYAYLSDLVYLDFRR 192
Cdd:COG4886   192 NQITDLpEPLGNLTNLEELDLSGNQLTDLPEP--LANLTNLETLDLSNNQLTDLPE-----LGNLTNLEELDLSN 259
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 70-144 1.80e-13

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 69.81  E-value: 1.80e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907083455  70 LQLNNNIIERIEGLTNLIHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSNNRISKVDSLDALVKLQVLSLGNNQIS 144
Cdd:cd21340     7 LYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRIS 81
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
61-146 2.95e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 71.50  E-value: 2.95e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455  61 LWQFENLKKLQLNNNIIERI-EGLTNLIHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSNNRISKVDSLDALVKLQVLSLG 139
Cdd:COG4886   201 LGNLTNLEELDLSGNQLTDLpEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLS 280


                  ....*..
gi 1907083455 140 NNQISNM 146
Cdd:COG4886   281 NNQLTDL 287
LRR_9 pfam14580
Leucine-rich repeat;
68-202 7.07e-12

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 64.01  E-value: 7.07e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455  68 KKLQLNNNIIERIEGL-TNLIHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSNNRISKV-DSLD-ALVKLQVLSLGNNQIS 144
Cdd:pfam14580  22 RELDLRGYKIPIIENLgATLDQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRIgEGLGeALPNLTELILTNNNLQ 101

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907083455 145 NMMNIIYLRRFPCLRTLSLAGNPVSEAEEYKMFIYAYLSDLVYLDFRRVDEQMREMAK 202
Cdd:pfam14580 102 ELGDLDPLASLKKLTFLSLLRNPVTNKPHYRLYVIYKVPQLRLLDFRKVKQKERQAAE 159
LRR_8 pfam13855
Leucine rich repeat;
88-143 5.02e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 46.75  E-value: 5.02e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455  88 HLVWLDLSFNNIEAIEG--LDTLVNLEDLSLSNNRISKV--DSLDALVKLQVLSLGNNQI 143
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLspGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
66-121 9.12e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.98  E-value: 9.12e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455  66 NLKKLQLNNNIIERIEG--LTNLIHLVWLDLSFNNIEAIEG--LDTLVNLEDLSLSNNRI 121
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 67-177 7.05e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 48.12  E-value: 7.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455  67 LKKLQLNNN------IIERIEGLTNLIHLVWLDLSFNNIEAI------EGLDTLVNLEDLSLSNNRISKVD-------SL 127
Cdd:cd00116   167 LKELNLANNgigdagIRALAEGLKANCNLEVLDLNNNGLTDEgasalaETLASLKSLEVLNLGDNNLTDAGaaalasaLL 246

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1907083455 128 DALVKLQVLSLGNNQISN---MMNIIYLRRFPCLRTLSLAGNPVSEAEEYKMF 177
Cdd:cd00116   247 SPNISLLTLSLSCNDITDdgaKDLAEVLAEKESLLELDLRGNKFGEEGAQLLA 299
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 110-145 4.14e-05

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 40.69  E-value: 4.14e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1907083455 110 NLEDLSLSNNRISKVDSLDALVKLQVLSL-GNNQISN 145
Cdd:pfam12799   2 NLEVLDLSNNQITDIPPLAKLPNLETLDLsGNNKITD 38
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
40-192 1.52e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 44.15  E-value: 1.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455  40 ILFKDVLSLQLDFQNILRIDNLWQFENLKKLQLNNNIIERIEGLTNLIHLVWLDLSFNNIEAIEGLDTLVNLEDLSLSNN 119
Cdd:COG4886    27 LLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN 106

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907083455 120 riskvDSLDALVKLQVLSLGNNQISNMmnIIYLRRFPCLRTLSLAGNPVSEAEEYKmfiyAYLSDLVYLDFRR 192
Cdd:COG4886   107 -----EELSNLTNLESLDLSGNQLTDL--PEELANLTNLKELDLSNNQLTDLPEPL----GNLTNLKSLDLSN 168
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 88-128 2.36e-04

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 38.77  E-value: 2.36e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1907083455  88 HLVWLDLSFNNIEAIEGLDTLVNLEDLSLS-NNRISKVDSLD 128
Cdd:pfam12799   2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSgNNKITDLSDLA 43
LRR_8 pfam13855
Leucine rich repeat;
110-168 3.37e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.66  E-value: 3.37e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907083455 110 NLEDLSLSNNRISKVD--SLDALVKLQVLSLGNNQISNmMNIIYLRRFPCLRTLSLAGNPV 168
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDdgAFKGLSNLKVLDLSNNLLTT-LSPGAFSGLPSLRYLDLSGNRL 61
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 66-106 5.44e-04

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 37.61  E-value: 5.44e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1907083455  66 NLKKLQLNNNIIERIEGLTNLIHLVWLDLSFNN-IEAIEGLD 106
Cdd:pfam12799   2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGNNkITDLSDLA 43
LRR_8 pfam13855
Leucine rich repeat;
47-99 1.43e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.12  E-value: 1.43e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907083455  47 SLQLDFQNILRIDNLW--QFENLKKLQLNNNIIERIEG--LTNLIHLVWLDLSFNNI 99
Cdd:pfam13855   5 SLDLSNNRLTSLDDGAfkGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 66-170 2.00e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 40.54  E-value: 2.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907083455  66 NLKKLQLNNNIIER------IEGLTNLIHLVWLDLSFNNIEA------IEGLDTLVNLEDLSLSNNRISKV------DSL 127
Cdd:COG5238   265 TVETLYLSGNQIGAegaialAKALQGNTTLTSLDLSVNRIGDegaialAEGLQGNKTLHTLNLAYNGIGAQgaialaKAL 344

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1907083455 128 DALVKLQVLSLGNNQISN--MMNII-YLRRFPCLRTLSLAGNPVSE 170
Cdd:COG5238   345 QENTTLHSLDLSDNQIGDegAIALAkYLEGNTTLRELNLGKNNIGK 390
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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