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Conserved domains on  [gi|1720409732|ref|XP_030109614|]
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arginine-glutamic acid dipeptide repeats protein isoform X17 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Atrophin-1 super family cl38111
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 14-1011 0e+00

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


The actual alignment was detected with superfamily member pfam03154:

Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 1022.39  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   14 GKHSMRTRRSRGSMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKST 93
Cdd:pfam03154    1 GKHSMRTRRSRGSMSTLRSGRKKQTASPDGRASPTNEDLRSSGRNSPSAASTSSNDSKAESMKKSSKKIKEEAPSPLKSA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   94 KRQREKVASDTEDTDRITSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 173
Cdd:pfam03154   81 KRQREKGASDTEEPERATAKKSKTQEISRPNSPSEGEGESSDGRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  174 SAQQQMLQAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATSQPPNQTQSTVAPaaHTHIQQAPTLH 253
Cdd:pfam03154  161 SAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAP--HTLIQQTPTLH 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  254 PPRLPSPHPPLQPMT--APPSQSSAQPHPQPSLHSQGPPGPHSLQTGP-LLQHPGPPQPFGLPSQPSQGQGPLGPSPAAA 330
Cdd:pfam03154  239 PQRLPSPHPPLQPMTqpPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPsHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAP 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  331 HP-HSTIQLPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSLNANLPPPPALKP 409
Cdd:pfam03154  319 GQsQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKP 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  410 LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTT-GLHQVPSQSPFPQHPFVPGGPPPITPP 488
Cdd:pfam03154  399 LSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTsGLHQVPSQSPFPQHPFVPGGPPPITPP 478

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  489 SCPPTSTPPAGPSSSSQPPcsAAVSSGGSVPGAPSCPLPAVQIKEEALDEAEEPESPPPPPRSPSPEPTVVDTPSHASQS 568
Cdd:pfam03154  479 SGPPTSTSSAMPGIQPPSS--ASVSSSGPVPAAVSCPLPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVVNTPSHASQS 556

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  569 ARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASS 648
Cdd:pfam03154  557 ARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEALEKAKREAEQKAREEKEREKEKEKEREREREREREAERAAKASS 636

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  649 SAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMP 728
Cdd:pfam03154  637 SSHEGRMGDPQLAGPAHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFFVPLNPTDPLLAYHMP 716

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  729 GLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHSALTIPPAAGPHPFASFHPG 808
Cdd:pfam03154  717 GLYNVDPAIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHGALTLPPMAGPHPFASFHPG 796

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  809 LNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAG 888
Cdd:pfam03154  797 LNPLERERLALAGPQLRPEMSYPDRLAAERLHAERMASLTNDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSGG 876

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  889 PVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFaepvlrlaGTPYPRDLPGAIPPPMSAAHQLQAMHA 968
Cdd:pfam03154  877 PVHPLVDPLAAGPHLARFPYPPGAIPNPLLGQPPHEHEMLRHPVF--------GTPYPRDLPGGLPPPMSAAHQLQAMHA 948

                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|...
gi 1720409732  969 QSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQ 1011
Cdd:pfam03154  949 QSAELQRLAMEQQWLHGHPHMHGGHLPGQEDYYSRLKKESDKQ 991
 
Name Accession Description Interval E-value
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 14-1011 0e+00

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 1022.39  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   14 GKHSMRTRRSRGSMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKST 93
Cdd:pfam03154    1 GKHSMRTRRSRGSMSTLRSGRKKQTASPDGRASPTNEDLRSSGRNSPSAASTSSNDSKAESMKKSSKKIKEEAPSPLKSA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   94 KRQREKVASDTEDTDRITSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 173
Cdd:pfam03154   81 KRQREKGASDTEEPERATAKKSKTQEISRPNSPSEGEGESSDGRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  174 SAQQQMLQAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATSQPPNQTQSTVAPaaHTHIQQAPTLH 253
Cdd:pfam03154  161 SAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAP--HTLIQQTPTLH 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  254 PPRLPSPHPPLQPMT--APPSQSSAQPHPQPSLHSQGPPGPHSLQTGP-LLQHPGPPQPFGLPSQPSQGQGPLGPSPAAA 330
Cdd:pfam03154  239 PQRLPSPHPPLQPMTqpPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPsHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAP 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  331 HP-HSTIQLPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSLNANLPPPPALKP 409
Cdd:pfam03154  319 GQsQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKP 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  410 LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTT-GLHQVPSQSPFPQHPFVPGGPPPITPP 488
Cdd:pfam03154  399 LSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTsGLHQVPSQSPFPQHPFVPGGPPPITPP 478

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  489 SCPPTSTPPAGPSSSSQPPcsAAVSSGGSVPGAPSCPLPAVQIKEEALDEAEEPESPPPPPRSPSPEPTVVDTPSHASQS 568
Cdd:pfam03154  479 SGPPTSTSSAMPGIQPPSS--ASVSSSGPVPAAVSCPLPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVVNTPSHASQS 556

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  569 ARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASS 648
Cdd:pfam03154  557 ARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEALEKAKREAEQKAREEKEREKEKEKEREREREREREAERAAKASS 636

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  649 SAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMP 728
Cdd:pfam03154  637 SSHEGRMGDPQLAGPAHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFFVPLNPTDPLLAYHMP 716

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  729 GLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHSALTIPPAAGPHPFASFHPG 808
Cdd:pfam03154  717 GLYNVDPAIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHGALTLPPMAGPHPFASFHPG 796

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  809 LNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAG 888
Cdd:pfam03154  797 LNPLERERLALAGPQLRPEMSYPDRLAAERLHAERMASLTNDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSGG 876

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  889 PVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFaepvlrlaGTPYPRDLPGAIPPPMSAAHQLQAMHA 968
Cdd:pfam03154  877 PVHPLVDPLAAGPHLARFPYPPGAIPNPLLGQPPHEHEMLRHPVF--------GTPYPRDLPGGLPPPMSAAHQLQAMHA 948

                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|...
gi 1720409732  969 QSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQ 1011
Cdd:pfam03154  949 QSAELQRLAMEQQWLHGHPHMHGGHLPGQEDYYSRLKKESDKQ 991
PHA03247 PHA03247
large tegument protein UL36; Provisional
 60-474 1.21e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 59.57  E-value: 1.21e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   60 PSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTEDTDRITSKKTKTQEISRPNSPSEGEGESSDSRSV 139
Cdd:PHA03247  2560 PPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPD 2639

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  140 NDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQA-QPPALQAPSGAASApSTAPPGTPQLPTQGPTPSATA 218
Cdd:PHA03247  2640 PHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRpRRRAARPTVGSLTS-LADPPPPPPTPEPAPHALVSA 2718

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  219 VP-PQGSPATSQPPNQTQSTVAPAAHTHIQQAPTLHPPRLPSPHPPLQPMTAPPSQSSAQPHPQPSLhsqgPPGPHSLQT 297
Cdd:PHA03247  2719 TPlPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTR----PAVASLSES 2794

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  298 GPLLQHPGPPQPFGLPSQPSQGQGPLGPSPAAAHPHSTIQLPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQL 377
Cdd:PHA03247  2795 RESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAK 2874

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  378 PAPQAH------KHPPHLSGPSPFSLNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSL 451
Cdd:PHA03247  2875 PAAPARppvrrlARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGE 2954

                          410       420
                   ....*....|....*....|...
gi 1720409732  452 PPPAASHPTTGlHQVPSQSPFPQ 474
Cdd:PHA03247  2955 PSGAVPQPWLG-ALVPGRVAVPR 2976
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 3-175 2.94e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 51.45  E-value: 2.94e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732    3 KPVKEEDDGLSGKHSMRTRRSR------GSMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVK 76
Cdd:NF033609   555 EPIPEDSDSDPGSDSGSDSSNSdsgsdsGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDS 634

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   77 KSAKKVKEEAASPLKSTKRQREKVASDTeDTDRITSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNR 155
Cdd:NF033609   635 DSASDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSD 713

                          170       180
                   ....*....|....*....|
gi 1720409732  156 STSPSiPSPQDNESDSDSSA 175
Cdd:NF033609   714 SDSDS-DSDSDSDSDSDSDS 732
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 46-206 2.76e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 48.37  E-value: 2.76e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   46 SPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTE-DTDRITSKKTKTQEISRPN 124
Cdd:NF033609   716 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSD 795

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  125 SPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPS-IPSPQDNESDSDSSAQQQMLQAQPPALQAPSGAASAPSTAPP 202
Cdd:NF033609   796 SDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVVPP 875


                   ....
gi 1720409732  203 GTPQ 206
Cdd:NF033609   876 NSPK 879
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 26-175 3.08e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.90  E-value: 3.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   26 SMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTE 105
Cdd:NF033609   630 SASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 709

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720409732  106 -DTDRITSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 175
Cdd:NF033609   710 sDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 780
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 26-175 5.26e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.13  E-value: 5.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   26 SMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTE 105
Cdd:NF033609   606 SASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 685

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720409732  106 -DTDRITSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 175
Cdd:NF033609   686 sDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 756
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 26-175 5.54e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.13  E-value: 5.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   26 SMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTe 105
Cdd:NF033609   654 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS- 732

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720409732  106 DTDRITSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 175
Cdd:NF033609   733 DSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 802
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 26-175 8.61e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.36  E-value: 8.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   26 SMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTE 105
Cdd:NF033609   600 SASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 679

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720409732  106 -DTDRITSKKTKTQEISRPNSPSEGEGES-----SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 175
Cdd:NF033609   680 sDSDSDSDSDSDSDSDSDSDSDSDSDSDSdsdsdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 754
 
Name Accession Description Interval E-value
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 14-1011 0e+00

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 1022.39  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   14 GKHSMRTRRSRGSMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKST 93
Cdd:pfam03154    1 GKHSMRTRRSRGSMSTLRSGRKKQTASPDGRASPTNEDLRSSGRNSPSAASTSSNDSKAESMKKSSKKIKEEAPSPLKSA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   94 KRQREKVASDTEDTDRITSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 173
Cdd:pfam03154   81 KRQREKGASDTEEPERATAKKSKTQEISRPNSPSEGEGESSDGRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  174 SAQQQMLQAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATSQPPNQTQSTVAPaaHTHIQQAPTLH 253
Cdd:pfam03154  161 SAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAP--HTLIQQTPTLH 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  254 PPRLPSPHPPLQPMT--APPSQSSAQPHPQPSLHSQGPPGPHSLQTGP-LLQHPGPPQPFGLPSQPSQGQGPLGPSPAAA 330
Cdd:pfam03154  239 PQRLPSPHPPLQPMTqpPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPsHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAP 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  331 HP-HSTIQLPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSLNANLPPPPALKP 409
Cdd:pfam03154  319 GQsQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKP 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  410 LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTT-GLHQVPSQSPFPQHPFVPGGPPPITPP 488
Cdd:pfam03154  399 LSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTsGLHQVPSQSPFPQHPFVPGGPPPITPP 478

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  489 SCPPTSTPPAGPSSSSQPPcsAAVSSGGSVPGAPSCPLPAVQIKEEALDEAEEPESPPPPPRSPSPEPTVVDTPSHASQS 568
Cdd:pfam03154  479 SGPPTSTSSAMPGIQPPSS--ASVSSSGPVPAAVSCPLPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVVNTPSHASQS 556

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  569 ARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASS 648
Cdd:pfam03154  557 ARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEALEKAKREAEQKAREEKEREKEKEKEREREREREREAERAAKASS 636

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  649 SAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMP 728
Cdd:pfam03154  637 SSHEGRMGDPQLAGPAHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFFVPLNPTDPLLAYHMP 716

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  729 GLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHSALTIPPAAGPHPFASFHPG 808
Cdd:pfam03154  717 GLYNVDPAIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHGALTLPPMAGPHPFASFHPG 796

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  809 LNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAG 888
Cdd:pfam03154  797 LNPLERERLALAGPQLRPEMSYPDRLAAERLHAERMASLTNDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSGG 876

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  889 PVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFaepvlrlaGTPYPRDLPGAIPPPMSAAHQLQAMHA 968
Cdd:pfam03154  877 PVHPLVDPLAAGPHLARFPYPPGAIPNPLLGQPPHEHEMLRHPVF--------GTPYPRDLPGGLPPPMSAAHQLQAMHA 948

                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|...
gi 1720409732  969 QSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQ 1011
Cdd:pfam03154  949 QSAELQRLAMEQQWLHGHPHMHGGHLPGQEDYYSRLKKESDKQ 991
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 178-344 4.22e-09

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 60.82  E-value: 4.22e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  178 QM-LQAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQgspatsQPPNQTQSTVAPAAHTHIQQAPTLHPPR 256
Cdd:pfam09770  202 AMrAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQ------QQPQQPQQHPGQGHPVTILQRPQSPQPD 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  257 LPSPHPPLQPMTAPPSQSSAQPHPQPSLhsQGPPGPHSLQTGPLLQHPGPPQPFGLPSQPSQGQGPLGPSPAAAHPHSTI 336
Cdd:pfam09770  276 PAQPSIQPQAQQFHQQPPPVPVQPTQIL--QNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQAPIITHPQQLA 353


                   ....*...
gi 1720409732  337 QLPASQSA 344
Cdd:pfam09770  354 QLSEEEKA 361
PHA03247 PHA03247
large tegument protein UL36; Provisional
 60-474 1.21e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 59.57  E-value: 1.21e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   60 PSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTEDTDRITSKKTKTQEISRPNSPSEGEGESSDSRSV 139
Cdd:PHA03247  2560 PPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPD 2639

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  140 NDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQA-QPPALQAPSGAASApSTAPPGTPQLPTQGPTPSATA 218
Cdd:PHA03247  2640 PHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRpRRRAARPTVGSLTS-LADPPPPPPTPEPAPHALVSA 2718

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  219 VP-PQGSPATSQPPNQTQSTVAPAAHTHIQQAPTLHPPRLPSPHPPLQPMTAPPSQSSAQPHPQPSLhsqgPPGPHSLQT 297
Cdd:PHA03247  2719 TPlPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTR----PAVASLSES 2794

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  298 GPLLQHPGPPQPFGLPSQPSQGQGPLGPSPAAAHPHSTIQLPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQL 377
Cdd:PHA03247  2795 RESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAK 2874

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  378 PAPQAH------KHPPHLSGPSPFSLNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSL 451
Cdd:PHA03247  2875 PAAPARppvrrlARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGE 2954

                          410       420
                   ....*....|....*....|...
gi 1720409732  452 PPPAASHPTTGlHQVPSQSPFPQ 474
Cdd:PHA03247  2955 PSGAVPQPWLG-ALVPGRVAVPR 2976
PHA03247 PHA03247
large tegument protein UL36; Provisional
 31-471 9.15e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.49  E-value: 9.15e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   31 RSGRKKQPTSPDGRASPiNEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTEDTDRI 110
Cdd:PHA03247  2588 RPDAPPQSARPRAPVDD-RGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRR 2666

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  111 TSKKTKTqeiSRPNSPSEGEGESSDSRSVNDEGSS-----DPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 185
Cdd:PHA03247  2667 ARRLGRA---AQASSPPQRPRRRAARPTVGSLTSLadpppPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPA 2743

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  186 AlqaPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATSQPPNQTQSTVAPAAhthiqqAPTLHPPRLPSPHPPLQ 265
Cdd:PHA03247  2744 V---PAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRES------LPSPWDPADPPAAVLAP 2814

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  266 PMTAPPSQSSAQPHPQPSLHSQGPPGPHSLQTGPLLQHPGPPQPFG-LPSQPSQGQGPLGPSPAAAHPHSTIQLPASQSA 344
Cdd:PHA03247  2815 AAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGdVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRS 2894

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  345 LQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSLNANLPPPPALKPLSSLSTHHPPSAHPP 424
Cdd:PHA03247  2895 TESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAV 2974

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 1720409732  425 PLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTTGLHQVPSQSP 471
Cdd:PHA03247  2975 PRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETDPPP 3021
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 162-332 2.84e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 51.53  E-value: 2.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  162 PSPQDNESDSDSSAQQQMLQAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATSQPPNQTQSTVAPA 241
Cdd:PRK07764   597 GEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGA 676

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  242 AHTHIQQAPTLHPPRLPSPHPPLQPMTAPPSQSSAQPHPQPSLH------SQGPPGPHSLQTGPLLQHPG-PPQPFGLPS 314
Cdd:PRK07764   677 APAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQppqaaqGASAPSPAADDPVPLPPEPDdPPDPAGAPA 756

                          170
                   ....*....|....*...
gi 1720409732  315 QPSQGQGPLGPSPAAAHP 332
Cdd:PRK07764   757 QPPPPPAPAPAAAPAAAP 774
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 3-175 2.94e-06

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 51.45  E-value: 2.94e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732    3 KPVKEEDDGLSGKHSMRTRRSR------GSMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVK 76
Cdd:NF033609   555 EPIPEDSDSDPGSDSGSDSSNSdsgsdsGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDS 634

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   77 KSAKKVKEEAASPLKSTKRQREKVASDTeDTDRITSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNR 155
Cdd:NF033609   635 DSASDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSD 713

                          170       180
                   ....*....|....*....|
gi 1720409732  156 STSPSiPSPQDNESDSDSSA 175
Cdd:NF033609   714 SDSDS-DSDSDSDSDSDSDS 732
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 180-332 3.67e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 51.14  E-value: 3.67e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  180 LQAQPPALQAPSGAASAPSTAPPGTPQL-------PTQGPTPSATAVPPQGSPATSQPPNQTQSTVAPAAHTHIQQAPTL 252
Cdd:PRK07764   580 GDWQVEAVVGPAPGAAGGEGPPAPASSGppeeaarPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAV 659

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  253 HPPRLPSPHPPLQPMTAPPSQSSAQPHPQPSLHSQGPPGPHSLQTGPLLQHPGP-PQPFGLPSQPSQGQGPLGPSPAAAH 331
Cdd:PRK07764   660 PDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQaDDPAAQPPQAAQGASAPSPAADDPV 739


                   .
gi 1720409732  332 P 332
Cdd:PRK07764   740 P 740
PHA03247 PHA03247
large tegument protein UL36; Provisional
 154-583 8.29e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 50.32  E-value: 8.29e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  154 NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPSG------AASAPSTAPPGTPQLPTQGPTPSATAV-PPQGSPA 226
Cdd:PHA03247  2565 DRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDdrgdprGPAPPSPLPPDTHAPDPPPPSPSPAANePDPHPPP 2644

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  227 TSQPPNQTQSTVAPAA-----HTHIQQAPTLHPPRLPSPHPPLQPMTAPPSQSSAQPHPQPSLHSQGPPGPHS---LQTG 298
Cdd:PHA03247  2645 TVPPPERPRDDPAPGRvsrprRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSatpLPPG 2724

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  299 PLLQHPGPPQPFGLPSQPSQGQGPLGPSPAAAHPHStiqlPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLP 378
Cdd:PHA03247  2725 PAAARQASPALPAAPAPPAVPAGPATPGGPARPARP----PTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPS 2800

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  379 APQAHKHPPHLSGPSPFSLNANLPPPPALKPLSSLSTHHPPSAHPPPLQL--------------MPQSQPLPSSPAQPPG 444
Cdd:PHA03247  2801 PWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLplggsvapggdvrrRPPSRSPAAKPAAPAR 2880

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  445 lTQSQSLPPPAASHPTTGLHQVPSQSPFPQHPfvPGGPPPITPPSCPPTSTPPAGPSSSSQPPCSAAVSSGGSVPGAPSC 524
Cdd:PHA03247  2881 -PPVRRLARPAVSRSTESFALPPDQPERPPQP--QAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSG 2957

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720409732  525 PLPAVQikeeaLDEAEEPESPPPPPRSPSPEPTVvdtPSHASQSARFYKHLDRGYNSCA 583
Cdd:PHA03247  2958 AVPQPW-----LGALVPGRVAVPRFRVPQPAPSR---EAPASSTPPLTGHSLSRVSSWA 3008
PLN02967 PLN02967
kinase
 4-133 1.24e-05

kinase


Pssm-ID: 215521 [Multi-domain]  Cd Length: 581  Bit Score: 49.27  E-value: 1.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732    4 PVKEEDDGLSGKHSMRTRRSRgsmstlRSGRKKQPTSPDGRASPINEDIRssgrNSPSAASTSSNDSKAETVKKSA---K 80
Cdd:PLN02967    57 AVDEEPDENGAVSKKKPTRSV------KRATKKTVVEISEPLEEGSELVV----NEDAALDKESKKTPRRTRRKAAaasS 126

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1720409732   81 KVKEEAASPLKSTKRQREKVASDTEDTDRITSKKTKTQEISRPNSPSEGEGES 133
Cdd:PLN02967   127 DVEEEKTEKKVRKRRKVKKMDEDVEDQGSESEVSDVEESEFVTSLENESEEEL 179
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 169-324 2.06e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 48.44  E-value: 2.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  169 SDSDSSAQQQMLQAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPAtsqPPNQTQSTVAPAAhthiQQ 248
Cdd:PRK07764   367 ASDDERGLLARLERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPA---PAAAPQPAPAPAP----AP 439

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720409732  249 APTlhpPRLPSPHPPLQPMTAPPSQSSAQPHPQPslhsQGPPGPHSLQTGPLLQHPGPPQPFGLPSQPSQGQGPLG 324
Cdd:PRK07764   440 APP---SPAGNAPAGGAPSPPPAAAPSAQPAPAP----AAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADD 508
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 46-206 2.76e-05

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 48.37  E-value: 2.76e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   46 SPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTE-DTDRITSKKTKTQEISRPN 124
Cdd:NF033609   716 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDsDSDSDSDSDSDSDSDSDSD 795

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  125 SPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPS-IPSPQDNESDSDSSAQQQMLQAQPPALQAPSGAASAPSTAPP 202
Cdd:NF033609   796 SDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVVPP 875


                   ....
gi 1720409732  203 GTPQ 206
Cdd:NF033609   876 NSPK 879
PRK10856 PRK10856
cytoskeleton protein RodZ;
163-244 5.02e-05

cytoskeleton protein RodZ;


Pssm-ID: 236776 [Multi-domain]  Cd Length: 331  Bit Score: 46.56  E-value: 5.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  163 SPQDNES---DSDSSAQQQMLQAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATSQPPNQTQSTVA 239
Cdd:PRK10856   155 SQNSGQSvplDTSTTTDPATTPAPAAPVDTTPTNSQTPAVATAPAPAVDPQQNAVVAPSQANVDTAATPAPAAPATPDGA 234


                   ....*
gi 1720409732  240 PAAHT 244
Cdd:PRK10856   235 APLPT 239
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 182-300 5.04e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 47.40  E-value: 5.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  182 AQPPAlqAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATSQPPNQTQSTVAPAAhthiqqAPTLHPPRLPSPH 261
Cdd:PRK14951   382 ARPEA--AAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAA------APAAVALAPAPPA 453

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1720409732  262 PPLQPMTAPPSQSSAQPH-PQPSLHSQGPPGPHSLQTGPL 300
Cdd:PRK14951   454 QAAPETVAIPVRVAPEPAvASAAPAPAAAPAAARLTPTEE 493
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 155-296 1.03e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 46.18  E-value: 1.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  155 RSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTP-------SATAVPPQGSPAT 227
Cdd:pfam09770  204 RAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVtilqrpqSPQPDPAQPSIQP 283

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720409732  228 SQPPNQTQSTVAPAAHTHIQQAPTLhpPRLPSPHPPLQPMTAPPSQSSAQPHPQPSLHSQGPP---GPHSLQ 296
Cdd:pfam09770  284 QAQQFHQQPPPVPVQPTQILQNPNR--LSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQAPiitHPQQLA 353
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 137-242 1.30e-04

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 46.04  E-value: 1.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  137 RSVNDEGSSDPK--DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPSGAASAPSTAPPgTPQLPTQGPTP 214
Cdd:PRK12270    17 QYLADPNSVDPSwrEFFADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPP-KPAAAAAAAAA 95

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1720409732  215 SATAVPPQGSPATSQPPNQTQSTV---APAA 242
Cdd:PRK12270    96 PAAPPAAAAAAAPAAAAVEDEVTPlrgAAAA 126
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 188-338 1.51e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 45.85  E-value: 1.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  188 QAPSGAASAPSTAPPGTPQlptQGPTPSATAVPPQGSPATSQPPNQTQSTVAPAAHTHIQQAPTLHPPRLPSPHPPLQPM 267
Cdd:PRK10263   738 DGPHEPLFTPIVEPVQQPQ---QPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQ 814

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720409732  268 TAPPS-QSSAQPHPQPSLHSQGP-PGPHSLQTGPLLQHPGPPQPFGLPSQPSQGQGPLGPSPAAAHPHSTIQL 338
Cdd:PRK10263   815 PQYQQpQQPVAPQPQYQQPQQPVaPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFAL 887
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 111-292 1.57e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.75  E-value: 1.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  111 TSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSA--QQQMLQAQPPALQ 188
Cdd:PRK07764   600 PPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDggDGWPAKAGGAAPA 679

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  189 APSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATSQPPNQTQSTVAPAAHTHIQQAPTLHPPRLPSPHPPLQPMT 268
Cdd:PRK07764   680 APPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPP 759

                          170       180
                   ....*....|....*....|....
gi 1720409732  269 APPSQSSAQPHPQPSLHSQGPPGP 292
Cdd:PRK07764   760 PPPAPAPAAAPAAAPPPSPPSEEE 783
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 26-175 3.08e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.90  E-value: 3.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   26 SMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTE 105
Cdd:NF033609   630 SASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 709

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720409732  106 -DTDRITSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 175
Cdd:NF033609   710 sDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 780
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 26-175 5.26e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.13  E-value: 5.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   26 SMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTE 105
Cdd:NF033609   606 SASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 685

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720409732  106 -DTDRITSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 175
Cdd:NF033609   686 sDSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 756
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 26-175 5.54e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.13  E-value: 5.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   26 SMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTe 105
Cdd:NF033609   654 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS- 732

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720409732  106 DTDRITSKKTKTQEISRPNSPSEGEGES-SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 175
Cdd:NF033609   733 DSDSDSDSDSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 802
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 69-239 8.16e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 43.56  E-value: 8.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   69 DSKAETVKKSAKKVKEEAAsPLKSTKRQREKVASDTEdtdriTSKKTKTQEISRPNSPSEGEGESSDSRSVNdEGSSDPK 148
Cdd:PRK14949   630 SPKEGDGKKSSADRKPKTP-PSRAPPASLSKPASSPD-----ASQTSASFDLDPDFELATHQSVPEAALASG-SAPAPPP 702

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  149 DIDQDNRstsPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATS 228
Cdd:PRK14949   703 VPDPYDR---PPWEEAPEVASANDGPNNAAEGNLSESVEDASNSELQAVEQQATHQPQVQAEAQSPASTTALTQTSSEVQ 779

                          170
                   ....*....|.
gi 1720409732  229 QPPNQTQSTVA 239
Cdd:PRK14949   780 DTELNLVLLSS 790
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 26-175 8.61e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 43.36  E-value: 8.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   26 SMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTE 105
Cdd:NF033609   600 SASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 679

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720409732  106 -DTDRITSKKTKTQEISRPNSPSEGEGES-----SDSRSVNDEGSSDPKDIDQDNRSTSPSiPSPQDNESDSDSSA 175
Cdd:NF033609   680 sDSDSDSDSDSDSDSDSDSDSDSDSDSDSdsdsdSDSDSDSDSDSDSDSDSDSDSDSDSDS-DSDSDSDSDSDSDS 754
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 162-322 8.74e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 43.32  E-value: 8.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  162 PSPQDNESDSDSSAQQQMLQAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQgspATSQPPNQTQSTVAPA 241
Cdd:PRK07994   368 PEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQ---LQRAQGATKAKKSEPA 444

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  242 AHTHIQQAPTLHPPRLPSPHPPLQPMTAPPSQSSAQPHPQPSLHSQGPPGPHSLQTGPLLQHPGPPQPFGLPSQPSQGQG 321
Cdd:PRK07994   445 AASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTPELAAKLAAEAIERD 524


                   .
gi 1720409732  322 P 322
Cdd:PRK07994   525 P 525
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
182-393 8.80e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 43.33  E-value: 8.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  182 AQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATSQPPnqtqstvAPAAHTHIQQAPTLHPPrlpsph 261
Cdd:PRK12323   379 AAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSP-------APEALAAARQASARGPG------ 445

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  262 pplqPMTAPPSQSSAQPHPQPSLHSQGPPGPHSLQTGPllqhPGPPQPFGLPSQPSQGQGP---LGPSPAAAHPHSTIQL 338
Cdd:PRK12323   446 ----GAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAA----PARAAPAAAPAPADDDPPPweeLPPEFASPAPAQPDAA 517

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1720409732  339 PASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 393
Cdd:PRK12323   518 PAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASG 572
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 181-301 1.13e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.78  E-value: 1.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  181 QAQPPALQAPSGAASAPSTAPPGTPQLPTQGPT---PSATAVPPQGSPATSQPPNqtQSTVAPAAHTHIQQAPTLHPPRL 257
Cdd:PRK14951   387 AAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAaapPAPVAAPAAAAPAAAPAAA--PAAVALAPAPPAQAAPETVAIPV 464

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1720409732  258 PSPHPPLQPMTAPPSqssaQPHPQPSLHSQGPPGPHSLQTGPLL 301
Cdd:PRK14951   465 RVAPEPAVASAAPAP----AAAPAAARLTPTEEGDVWHATVQQL 504
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
137-249 1.16e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 42.84  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  137 RSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPAlqAPSGAASAPSTAPPGTPQLPTQGPTPSA 216
Cdd:PRK14971   363 TQKGDDASGGRGPKQHIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPS--APQSATQPAGTPPTVSVDPPAAVPVNPP 440

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1720409732  217 TAVPPQGSPATSQPPNQ----TQSTVAPAAHTHIQQA 249
Cdd:PRK14971   441 STAPQAVRPAQFKEEKKipvsKVSSLGPSTLRPIQEK 477
PTZ00112 PTZ00112
origin recognition complex 1 protein; Provisional
 19-185 1.51e-03

origin recognition complex 1 protein; Provisional


Pssm-ID: 240274 [Multi-domain]  Cd Length: 1164  Bit Score: 42.67  E-value: 1.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   19 RTRRSRGSMSTLRSGRKKQPTSPDG-RASPINEDI---RSSGRNSPSAASTSSNDSKA--ETVKKSAKKVKEEAASPLKS 92
Cdd:PTZ00112   203 KMRRSPRNTSTIKNNTNDKNKEKNKeKDKNIKKDRdgdKQTKRNSEKSKVQNSHFDVRilRSYTKENKKDEKNVVSGIRS 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   93 T---KRQREKVASDTeDTDRITSKKTKTQEisrpnsPSEGEGESSDSRSVNDEGSSDPKDIdQDNRSTSPSIPSPQDNES 169
Cdd:PTZ00112   283 SvllKRKSQCLRKDS-YVYSNHQKKAKTGD------PKNIIHRNNGSSNSNNDDTSSSNHL-GSNRISNRNPSSPYKKQT 354

                          170
                   ....*....|....*.
gi 1720409732  170 DSDSSAQQQMLQAQPP 185
Cdd:PTZ00112   355 TTKHTNNTKNNKYNKT 370
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 132-241 3.03e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.61  E-value: 3.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  132 ESSDSRSVNDEGSSDP---KDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPSGAASAPSTAPPGTPQLP 208
Cdd:PRK10263   728 EFSPMKALLDDGPHEPlftPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQP 807

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1720409732  209 TQGPTPSATAVPPQGSPATSQPPNQTQSTVAPA 241
Cdd:PRK10263   808 QQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQ 840
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 183-271 3.32e-03

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 41.41  E-value: 3.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  183 QPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPqGSPATSQPPNQTQSTVAPAAHTHIQQAPTLHPPRLPSPHP 262
Cdd:PRK12270    37 GPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPP-AAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVED 115


                   ....*....
gi 1720409732  263 PLQPMTAPP 271
Cdd:PRK12270   116 EVTPLRGAA 124
dnaA PRK14086
chromosomal replication initiator protein DnaA;
155-326 3.89e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 40.96  E-value: 3.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  155 RSTSPSIPSPQDNESDSDSSAQQQMLQAQP--PALQAPSGAASAPSTAPPGTPQLPTQGPTPSAtavpPQGSPATSQPPn 232
Cdd:PRK14086   115 RRPYEGYGGPRADDRPPGLPRQDQLPTARPayPAYQQRPEPGAWPRAADDYGWQQQRLGFPPRA----PYASPASYAPE- 189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  233 qtQSTVAPAAHTHIQQAPTLHPPRLPSPHPPLQpmtaPPSQSSAQPHPQPS---LHSQGPPGPHSLQTGPLLQHPGPPQP 309
Cdd:PRK14086   190 --QERDREPYDAGRPEYDQRRRDYDHPRPDWDR----PRRDRTDRPEPPPGaghVHRGGPGPPERDDAPVVPIRPSAPGP 263

                          170
                   ....*....|....*..
gi 1720409732  310 FglPSQPSQGQGPLGPS 326
Cdd:PRK14086   264 L--AAQPAPAPGPGEPT 278
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 182-271 4.36e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 40.95  E-value: 4.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  182 AQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSAtavPPQGSPATsqPPNQTQSTVAPAAHTHIQQAPTLHPPRLPSPH 261
Cdd:PRK14950   366 PQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPK---EPVRETAT--PPPVPPRPVAPPVPHTPESAPKLTRAAIPVDE 440

                           90
                   ....*....|
gi 1720409732  262 PPLQPMTAPP 271
Cdd:PRK14950   441 KPKYTPPAPP 450
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 171-394 4.55e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 41.17  E-value: 4.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  171 SDSSAQQQML-QAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATA------------------------VPPQGSP 225
Cdd:pfam09770   92 SDAIEEEQVRfNRQQPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVrtgyekykepepipdlqvdaslwgVAPKKAA 171

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  226 ATSQPPnqtqsTVAPAAHTHIQQAPTLHPPRLPSPHPPLQpmTAPPSQSSAQPHPQPSLHSQGPPGPHSLQTGPLLQHPG 305
Cdd:pfam09770  172 APAPAP-----QPAAQPASLPAPSRKMMSLEEVEAAMRAQ--AKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQ 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  306 PPQPFGLPSQPSQGQGPlgpsPAAAHPHSTI-QLPASQSALQPQQPPREQPLPPAPLAMPHI---------KPPPTTPIP 375
Cdd:pfam09770  245 QPQQQPQQPQQHPGQGH----PVTILQRPQSpQPDPAQPSIQPQAQQFHQQPPPVPVQPTQIlqnpnrlsaARVGYPQNP 320

                          250
                   ....*....|....*....
gi 1720409732  376 QLPAPQAHKHPPHLSGPSP 394
Cdd:pfam09770  321 QPGVQPAPAHQAHRQQGSF 339
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 179-309 4.66e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.85  E-value: 4.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  179 MLQAQPP-ALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATSQPPNQTQSTVAPAAhthiqQAPTLHPPRL 257
Cdd:PRK14951   361 LLAFKPAaAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAP-----VAAPAAAAPA 435

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1720409732  258 PSPHPPLQPMTAPPSQSSAQPHPQPSLHSQGPPGPHSLQTGPLlqHPGPPQP 309
Cdd:PRK14951   436 AAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPA--PAAAPAA 485
PRK08581 PRK08581
amidase domain-containing protein;
39-301 4.87e-03

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 40.93  E-value: 4.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732   39 TSPDGRASPINEDIRSSGRNSPSAASTSsNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTEDTDRITS---KKT 115
Cdd:PRK08581    21 TSPTAYADDPQKDSTAKTTSHDSKKSND-DETSKDTSSKDTDKADNNNTSNQDNNDKKFSTIDSSTSDSNNIIDfiyKNL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  116 KTQEISRPNSPSEGEGESSDSRSVNDEGSSDpKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPAL----QAPS 191
Cdd:PRK08581   100 PQTNINQLLTKNKYDDNYSLTTLIQNLFNLN-SDISDYEQPRNSEKSTNDSNKNSDSSIKNDTDTQSSKQDKadnqKAPS 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  192 GAASAPST-------APPGTPQLPTQGPTPSATAVPPQGS--------------------PATSQPPNQTQSTVAPAAHT 244
Cdd:PRK08581   179 SNNTKPSTsnkqpnsPKPTQPNQSNSQPASDDTANQKSSSkdnqsmsdsaldsildqyseDAKKTQKDYASQSKKDKTET 258

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1720409732  245 HIQQAPTLHPPRLPSPhpplqpmTAPPSQSSAQPHPQPSLHSQgppgpHSLQTGPLL 301
Cdd:PRK08581   259 SNTKNPQLPTQDELKH-------KSKPAQSFENDVNQSNTRST-----SLFETGPSL 303
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
170-275 7.38e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 40.14  E-value: 7.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  170 DSDSSAQQQMLQAQPPALQAPSgAASAPSTAPPGTPQLPTQGPTPSatavPPQGSPATSQPPNQTQSTVAPAAHTHIQQA 249
Cdd:PRK14971   366 GDDASGGRGPKQHIKPVFTQPA-AAPQPSAAAAASPSPSQSSAAAQ----PSAPQSATQPAGTPPTVSVDPPAAVPVNPP 440

                           90       100
                   ....*....|....*....|....*.
gi 1720409732  250 PTLHPPRLPSPHPPLQPMtaPPSQSS 275
Cdd:PRK14971   441 STAPQAVRPAQFKEEKKI--PVSKVS 464
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
157-339 8.34e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 40.24  E-value: 8.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  157 TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQ----GSPATSQPPN 232
Cdd:PRK12323   400 AAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAaagpRPVAAAAAAA 479

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  233 QTQSTVAPAAHTHIQQAPTLHPPRLPSPHPPLQPMTAPPSQSSAQPHPQPSLHSQGPPGPHSLQT---GPLLQHPGPPQP 309
Cdd:PRK12323   480 PARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPApaaAPAPRAAAATEP 559

                          170       180       190
                   ....*....|....*....|....*....|
gi 1720409732  310 FGLPSQPSQGQGPLGPSPAAAHPHSTIQLP 339
Cdd:PRK12323   560 VVAPRPPRASASGLPDMFDGDWPALAARLP 589
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 191-306 8.64e-03

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 40.10  E-value: 8.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  191 SGAASAPSTAPpgTPQLPTQGPTPSATAVPPQGSPATSQPPNQTQSTVAPAAHTHIQQAPTlhpprlPSPHPPLQPMTAP 270
Cdd:PHA03269    17 LIIANLNTNIP--IPELHTSAATQKPDPAPAPHQAASRAPDPAVAPTSAASRKPDLAQAPT------PAASEKFDPAPAP 88

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1720409732  271 PSQSSAQPHPQ--PSLHSQGPPGPHSLQTGPLLQHPGP 306
Cdd:PHA03269    89 HQAASRAPDPAvaPQLAAAPKPDAAEAFTSAAQAHEAP 126
PHA03247 PHA03247
large tegument protein UL36; Provisional
 185-530 9.64e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 9.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  185 PALQAPSGAASApsTAPPGTPQlPTQGPTPSATAVPPQGSPATSQPPNQTQ-STVAPAAHTHIQQAPTLHPPRLPSPHPP 263
Cdd:PHA03247  2478 PVYRRPAEARFP--FAAGAAPD-PGGGGPPDPDAPPAPSRLAPAILPDEPVgEPVHPRMLTWIRGLEELASDDAGDPPPP 2554

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  264 LQPMTAPPSQSSAQPHPQPSLHSQGPPGPHSLQTGPLLQHPGPPQPFGLPSQPSQGQGPLGPSPAAAH--------PHST 335
Cdd:PHA03247  2555 LPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHapdppppsPSPA 2634

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  336 IQLPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGP-SPFSLNANLPPPPALKPLSSLS 414
Cdd:PHA03247  2635 ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTvGSLTSLADPPPPPPTPEPAPHA 2714

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720409732  415 THHPPSAHPPPLQLMPQSQPLPSSPAQP--------PGLTQSQSLPPPAASHPTTGLHQVPSQSPFPQHPfvpGGPPPIT 486
Cdd:PHA03247  2715 LVSATPLPPGPAAARQASPALPAAPAPPavpagpatPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT---RPAVASL 2791

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 1720409732  487 PPSCPPTSTPPAGPSSSSQPPCSAAVSSGGSVPGAPSCPLPAVQ 530
Cdd:PHA03247  2792 SESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQ 2835
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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