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Conserved domains on  [gi|1720380607|ref|XP_030103845|]
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general transcription factor IIF subunit 2 isoform X1 [Mus musculus]

Protein Classification

TFIIF_beta domain-containing protein( domain architecture ID 10491598)

TFIIF_beta domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TFIIF_beta pfam02270
TFIIF, beta subunit HTH domain; Accurate transcription in vivo requires at least six general ...
 52-116 6.68e-31

TFIIF, beta subunit HTH domain; Accurate transcription in vivo requires at least six general transcription initiation factors, in addition to RNA polymerase II. Transcription initiation factor IIF (TFIIF) is a tetramer of two beta subunits associate with two alpha subunits which interacts directly with RNA polymerase II. The beta subunit of TFIIF is required for recruitment of RNA polymerase II onto the promoter.


:

Pssm-ID: 426691  Cd Length: 65  Bit Score: 104.62  E-value: 6.68e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720380607  52 ARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVGYLKEILKEIGIQNVKGIHKNTWELKPEYR 116
Cdd:pfam02270   1 ARMPRNELLDALFSLFEEHQYWSLKDLRERTRQPEAYLKETLEEIAVLNRSGPFAGMWELKPEYR 65
 
Name Accession Description Interval E-value
TFIIF_beta pfam02270
TFIIF, beta subunit HTH domain; Accurate transcription in vivo requires at least six general ...
 52-116 6.68e-31

TFIIF, beta subunit HTH domain; Accurate transcription in vivo requires at least six general transcription initiation factors, in addition to RNA polymerase II. Transcription initiation factor IIF (TFIIF) is a tetramer of two beta subunits associate with two alpha subunits which interacts directly with RNA polymerase II. The beta subunit of TFIIF is required for recruitment of RNA polymerase II onto the promoter.


Pssm-ID: 426691  Cd Length: 65  Bit Score: 104.62  E-value: 6.68e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720380607  52 ARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVGYLKEILKEIGIQNVKGIHKNTWELKPEYR 116
Cdd:pfam02270   1 ARMPRNELLDALFSLFEEHQYWSLKDLRERTRQPEAYLKETLEEIAVLNRSGPFAGMWELKPEYR 65
TFG2 COG5090
Transcription initiation factor IIF, small subunit (RAP30) [Transcription];
43-123 5.06e-20

Transcription initiation factor IIF, small subunit (RAP30) [Transcription];


Pssm-ID: 227421 [Multi-domain]  Cd Length: 297  Bit Score: 82.70  E-value: 5.06e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720380607  43 RKKKEDGKRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVGYLKEILKEIGIQNVKGIHKNTWELKPEYRHYQTEE 122
Cdd:COG5090   180 KKMLMDKKRERLPKNEVLDMLFKAFEKYPYWTLKGLAEFCGQPEAFLKEILDDIAVLNKKGPYANKYELRPEYKQTMDEL 259


                  .
gi 1720380607 123 K 123
Cdd:COG5090   260 R 260
 
Name Accession Description Interval E-value
TFIIF_beta pfam02270
TFIIF, beta subunit HTH domain; Accurate transcription in vivo requires at least six general ...
 52-116 6.68e-31

TFIIF, beta subunit HTH domain; Accurate transcription in vivo requires at least six general transcription initiation factors, in addition to RNA polymerase II. Transcription initiation factor IIF (TFIIF) is a tetramer of two beta subunits associate with two alpha subunits which interacts directly with RNA polymerase II. The beta subunit of TFIIF is required for recruitment of RNA polymerase II onto the promoter.


Pssm-ID: 426691  Cd Length: 65  Bit Score: 104.62  E-value: 6.68e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720380607  52 ARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVGYLKEILKEIGIQNVKGIHKNTWELKPEYR 116
Cdd:pfam02270   1 ARMPRNELLDALFSLFEEHQYWSLKDLRERTRQPEAYLKETLEEIAVLNRSGPFAGMWELKPEYR 65
TFG2 COG5090
Transcription initiation factor IIF, small subunit (RAP30) [Transcription];
43-123 5.06e-20

Transcription initiation factor IIF, small subunit (RAP30) [Transcription];


Pssm-ID: 227421 [Multi-domain]  Cd Length: 297  Bit Score: 82.70  E-value: 5.06e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720380607  43 RKKKEDGKRARADKQHVLDMLFSAFEKHQYYNLKDLVDITKQPVGYLKEILKEIGIQNVKGIHKNTWELKPEYRHYQTEE 122
Cdd:COG5090   180 KKMLMDKKRERLPKNEVLDMLFKAFEKYPYWTLKGLAEFCGQPEAFLKEILDDIAVLNKKGPYANKYELRPEYKQTMDEL 259


                  .
gi 1720380607 123 K 123
Cdd:COG5090   260 R 260
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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