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Conserved domains on  [gi|1720365518|ref|XP_030101724|]
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proline-rich protein 15-like protein isoform X1 [Mus musculus]

Protein Classification

ATAD4 domain-containing protein( domain architecture ID 10633964)

ATAD4 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATAD4 pfam15321
ATPase family AAA domain containing 4; ATAD4 is a family of proteins is found in eukaryotes. ...
 6-87 2.77e-29

ATPase family AAA domain containing 4; ATAD4 is a family of proteins is found in eukaryotes. The family is also known as PRR15L, or proline-rich 15-like. ATAD4 is expressed almost exclusively in post-mitotic cells both during foetal development and in adult tissues, such as the intestinal epithelium and the testis. Its expression in mouse and human gastrointestinal tumours is linked, directly or indirectly, to the disruption of the Wnt signaling pathway.


:

Pssm-ID: 464644  Cd Length: 95  Bit Score: 100.65  E-value: 2.77e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365518   6 WWK-LTFLRKKKSTPKVLY----EIPDTYAQTEGGAEPPGPDA------GDPHSDFNSRLEKIVDK--NTKGKHVKVSNS 72
Cdd:pfam15321   1 WWKsLTFLRKKKSQSKVLYgppdETPEETPSNDRPASPRENNHppnlggGDPPRQFDARLEKIVDDksGTKRRHVKVSHS 80

                          90
                  ....*....|....*
gi 1720365518  73 GRFKEKKKVRAMLAE 87
Cdd:pfam15321  81 GRFKEKKKVRATLAD 95
 
Name Accession Description Interval E-value
ATAD4 pfam15321
ATPase family AAA domain containing 4; ATAD4 is a family of proteins is found in eukaryotes. ...
 6-87 2.77e-29

ATPase family AAA domain containing 4; ATAD4 is a family of proteins is found in eukaryotes. The family is also known as PRR15L, or proline-rich 15-like. ATAD4 is expressed almost exclusively in post-mitotic cells both during foetal development and in adult tissues, such as the intestinal epithelium and the testis. Its expression in mouse and human gastrointestinal tumours is linked, directly or indirectly, to the disruption of the Wnt signaling pathway.


Pssm-ID: 464644  Cd Length: 95  Bit Score: 100.65  E-value: 2.77e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365518   6 WWK-LTFLRKKKSTPKVLY----EIPDTYAQTEGGAEPPGPDA------GDPHSDFNSRLEKIVDK--NTKGKHVKVSNS 72
Cdd:pfam15321   1 WWKsLTFLRKKKSQSKVLYgppdETPEETPSNDRPASPRENNHppnlggGDPPRQFDARLEKIVDDksGTKRRHVKVSHS 80

                          90
                  ....*....|....*
gi 1720365518  73 GRFKEKKKVRAMLAE 87
Cdd:pfam15321  81 GRFKEKKKVRATLAD 95
 
Name Accession Description Interval E-value
ATAD4 pfam15321
ATPase family AAA domain containing 4; ATAD4 is a family of proteins is found in eukaryotes. ...
 6-87 2.77e-29

ATPase family AAA domain containing 4; ATAD4 is a family of proteins is found in eukaryotes. The family is also known as PRR15L, or proline-rich 15-like. ATAD4 is expressed almost exclusively in post-mitotic cells both during foetal development and in adult tissues, such as the intestinal epithelium and the testis. Its expression in mouse and human gastrointestinal tumours is linked, directly or indirectly, to the disruption of the Wnt signaling pathway.


Pssm-ID: 464644  Cd Length: 95  Bit Score: 100.65  E-value: 2.77e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365518   6 WWK-LTFLRKKKSTPKVLY----EIPDTYAQTEGGAEPPGPDA------GDPHSDFNSRLEKIVDK--NTKGKHVKVSNS 72
Cdd:pfam15321   1 WWKsLTFLRKKKSQSKVLYgppdETPEETPSNDRPASPRENNHppnlggGDPPRQFDARLEKIVDDksGTKRRHVKVSHS 80

                          90
                  ....*....|....*
gi 1720365518  73 GRFKEKKKVRAMLAE 87
Cdd:pfam15321  81 GRFKEKKKVRATLAD 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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