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Conserved domains on  [gi|1720431393|ref|XP_030100185|]
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tetratricopeptide repeat protein 12 isoform X2 [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 1002571)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN03088 super family cl33632
SGT1, suppressor of G2 allele of SKP1; Provisional
 79-248 7.82e-14

SGT1, suppressor of G2 allele of SKP1; Provisional


The actual alignment was detected with superfamily member PLN03088:

Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 73.28  E-value: 7.82e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  79 LADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAH 158
Cdd:PLN03088    1 MAKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTAC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393 159 VALKNYSKAKECYQK---IEEINPKLKAQVKEhLNQVTLREKADLQEK--EAQESLDSGKNTAVTTKNLLETLSKPGQTP 233
Cdd:PLN03088   81 MKLEEYQTAKAALEKgasLAPGDSRFTKLIKE-CDEKIAEEEKDLVQPvpSDLPSSVTAPPVEEADATPVVPPSKPKYRH 159

                         170
                  ....*....|....*
gi 1720431393 234 LFYAGGIEILTEMMA 248
Cdd:PLN03088  160 EFYQKPEEVVVTVFA 174
 
Name Accession Description Interval E-value
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 79-248 7.82e-14

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 73.28  E-value: 7.82e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  79 LADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAH 158
Cdd:PLN03088    1 MAKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTAC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393 159 VALKNYSKAKECYQK---IEEINPKLKAQVKEhLNQVTLREKADLQEK--EAQESLDSGKNTAVTTKNLLETLSKPGQTP 233
Cdd:PLN03088   81 MKLEEYQTAKAALEKgasLAPGDSRFTKLIKE-CDEKIAEEEKDLVQPvpSDLPSSVTAPPVEEADATPVVPPSKPKYRH 159

                         170
                  ....*....|....*
gi 1720431393 234 LFYAGGIEILTEMMA 248
Cdd:PLN03088  160 EFYQKPEEVVVTVFA 174
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
79-180 1.04e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.58  E-value: 1.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  79 LADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAH 158
Cdd:COG0457     7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAL 86

                          90       100
                  ....*....|....*....|..
gi 1720431393 159 VALKNYSKAKECYQKIEEINPK 180
Cdd:COG0457    87 QALGRYEEALEDYDKALELDPD 108
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 9-247 7.99e-11

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 65.01  E-value: 7.99e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393   9 QQKAVLDSEKKLLLMEREQEEDGCRTTLNKTMISPPQTPEN-----ADEMSPDAFLASVEKDAKERAKrrrenrvLADAL 83
Cdd:TIGR00990  58 KGQQQRESKPKISKKERRKRKQAEKETEGKTEEKKSTAPKNapvepADELPEIDESSVANLSEEERKK-------YAAKL 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  84 KEKGNEAFVRGDYETAIFFYSEGLgKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAHVALKN 163
Cdd:TIGR00990 131 KEKGNKAYRNKDFNKAIKLYSKAI-ECKPDPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGK 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393 164 YSKA-----KECYqkIEEINPKLKAQVKEHLnqvtLREKADLQEKEAQESLDSGKNTAVTTKNLLETLsKPGQTPLFYAG 238
Cdd:TIGR00990 210 YADAlldltASCI--IDGFRNEQSAQAVERL----LKKFAESKAKEILETKPENLPSVTFVGNYLQSF-RPKPRPAGLED 282


                  ....*....
gi 1720431393 239 GIEILTEMM 247
Cdd:TIGR00990 283 SNELDEETG 291
TPR_1 pfam00515
Tetratricopeptide repeat;
149-180 3.23e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 41.25  E-value: 3.23e-05
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1720431393 149 KAYFHMGKAHVALKNYSKAKECYQKIEEINPK 180
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 149-180 8.89e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 40.12  E-value: 8.89e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1720431393  149 KAYFHMGKAHVALKNYSKAKECYQKIEEINPK 180
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
 
Name Accession Description Interval E-value
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 79-248 7.82e-14

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 73.28  E-value: 7.82e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  79 LADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAH 158
Cdd:PLN03088    1 MAKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTAC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393 159 VALKNYSKAKECYQK---IEEINPKLKAQVKEhLNQVTLREKADLQEK--EAQESLDSGKNTAVTTKNLLETLSKPGQTP 233
Cdd:PLN03088   81 MKLEEYQTAKAALEKgasLAPGDSRFTKLIKE-CDEKIAEEEKDLVQPvpSDLPSSVTAPPVEEADATPVVPPSKPKYRH 159

                         170
                  ....*....|....*
gi 1720431393 234 LFYAGGIEILTEMMA 248
Cdd:PLN03088  160 EFYQKPEEVVVTVFA 174
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
79-180 1.04e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.58  E-value: 1.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  79 LADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAH 158
Cdd:COG0457     7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAL 86

                          90       100
                  ....*....|....*....|..
gi 1720431393 159 VALKNYSKAKECYQKIEEINPK 180
Cdd:COG0457    87 QALGRYEEALEDYDKALELDPD 108
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
80-207 3.60e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.87  E-value: 3.60e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  80 ADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAHV 159
Cdd:COG0457    76 AEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1720431393 160 ALKNYSKAKECYQKIEEINPKLKAQVKEHLNQVTLREKADLQEKEAQE 207
Cdd:COG0457   156 KLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLAL 203
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 66-191 5.53e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 60.40  E-value: 5.53e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  66 AKERAKRRRENrvlADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDE 145
Cdd:COG4235     6 LRQALAANPND---AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDP 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1720431393 146 NCTKAYFHMGKAHVALKNYSKAKECYQKIEEINPK--LKAQVKEHLNQ 191
Cdd:COG4235    83 DNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAdaPARLLEASIAE 130
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 9-247 7.99e-11

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 65.01  E-value: 7.99e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393   9 QQKAVLDSEKKLLLMEREQEEDGCRTTLNKTMISPPQTPEN-----ADEMSPDAFLASVEKDAKERAKrrrenrvLADAL 83
Cdd:TIGR00990  58 KGQQQRESKPKISKKERRKRKQAEKETEGKTEEKKSTAPKNapvepADELPEIDESSVANLSEEERKK-------YAAKL 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  84 KEKGNEAFVRGDYETAIFFYSEGLgKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAHVALKN 163
Cdd:TIGR00990 131 KEKGNKAYRNKDFNKAIKLYSKAI-ECKPDPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGK 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393 164 YSKA-----KECYqkIEEINPKLKAQVKEHLnqvtLREKADLQEKEAQESLDSGKNTAVTTKNLLETLsKPGQTPLFYAG 238
Cdd:TIGR00990 210 YADAlldltASCI--IDGFRNEQSAQAVERL----LKKFAESKAKEILETKPENLPSVTFVGNYLQSF-RPKPRPAGLED 282


                  ....*....
gi 1720431393 239 GIEILTEMM 247
Cdd:TIGR00990 283 SNELDEETG 291
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
56-211 1.65e-10

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 61.47  E-value: 1.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  56 DAFLASVEKDAKERAKRRRENRVLADALKEKGNEAFVRGDYETAIFFYSEGLgKLK-DMKVLYTNRAQAFIKLGDYQKAL 134
Cdd:COG4785    49 AAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQAL-ELDpDLAEAYNNRGLAYLLLGDYDAAL 127

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720431393 135 VDCDWALKCDENCTKAYFHMGKAHVALKNYSKAKECYQKIEEINPKLKAQV-KEHLNQvtlrekADLQEKEAQESLDS 211
Cdd:COG4785   128 EDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERAlWLYLAE------RKLDPEKALALLLE 199
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 80-180 7.81e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 57.51  E-value: 7.81e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  80 ADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAHV 159
Cdd:COG4783     4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                          90       100
                  ....*....|....*....|.
gi 1720431393 160 ALKNYSKAKECYQKIEEINPK 180
Cdd:COG4783    84 KAGDYDEALALLEKALKLDPE 104
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 80-211 8.69e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.13  E-value: 8.69e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  80 ADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAHV 159
Cdd:COG2956   110 AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYL 189

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1720431393 160 ALKNYSKAKECYQKIEEINPKlKAQVKEHLNQVTLREKadlQEKEAQESLDS 211
Cdd:COG2956   190 EQGDYEEAIAALERALEQDPD-YLPALPRLAELYEKLG---DPEEALELLRK 237
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
93-181 1.61e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 55.18  E-value: 1.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  93 RGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALvDCDWALKCDENCTKAYFHMGKAHVALKNYSKAKECYQ 172
Cdd:COG3063     5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLE 83


                  ....*....
gi 1720431393 173 KIEEINPKL 181
Cdd:COG3063    84 RALELDPSA 92
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 57-179 5.81e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.35  E-value: 5.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  57 AFLASVEKDAKERAKRRRENRVLADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVD 136
Cdd:COG5010    31 LAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEY 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1720431393 137 CDWALKCDENCTKAYFHMGKAHVALKNYSKAKECYQKIEEINP 179
Cdd:COG5010   111 YEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 80-180 6.68e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.85  E-value: 6.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  80 ADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAHV 159
Cdd:COG3914   112 AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQ 191

                          90       100
                  ....*....|....*....|.
gi 1720431393 160 ALKNYSKAKECYQKIEEINPK 180
Cdd:COG3914   192 DLGRLEEAIAAYRRALELDPD 212
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 80-180 9.22e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.43  E-value: 9.22e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  80 ADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAHV 159
Cdd:COG4783    38 PEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYR 117

                          90       100
                  ....*....|....*....|.
gi 1720431393 160 ALKNYSKAKECYQKIEEINPK 180
Cdd:COG4783   118 ALGRPDEAIAALEKALELDPD 138
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 80-210 4.15e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.12  E-value: 4.15e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  80 ADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAHV 159
Cdd:COG2956    42 VEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYE 121

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1720431393 160 ALKNYSKAKECYQKIEEINPKlKAQVKEHLNQVTLREKadlQEKEAQESLD 210
Cdd:COG2956   122 QEGDWEKAIEVLERLLKLGPE-NAHAYCELAELYLEQG---DYDEAIEALE 168
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 68-180 9.84e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.96  E-value: 9.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  68 ERAKRRRENRvlADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENC 147
Cdd:COG2956    66 QKLLERDPDR--AEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN 143

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1720431393 148 TKAYFHMGKAHVALKNYSKAKECYQKIEEINPK 180
Cdd:COG2956   144 AHAYCELAELYLEQGDYDEAIEALEKALKLDPD 176
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 64-179 3.12e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 52.42  E-value: 3.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  64 KDAKERAKR-RRENRVLADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALK 142
Cdd:COG2956   127 EKAIEVLERlLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE 206

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1720431393 143 CDENCTKAYFHMGKAHVALKNYSKAKECYQKIEEINP 179
Cdd:COG2956   207 QDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP 243
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
50-180 4.19e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.45  E-value: 4.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  50 ADEMSPDAFLASVEKDAKERAKRRRENRVLADALKEKGNEAFVRGDYETAIFFYSEGLG---KLKDMKVLYTNRAQAFIK 126
Cdd:COG4785     6 LALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDralALPDLAQLYYERGVAYDS 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1720431393 127 LGDYQKALVDCDWALKCDENCTKAYFHMGKAHVALKNYSKAKECYQKIEEINPK 180
Cdd:COG4785    86 LGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 40-202 8.54e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 52.30  E-value: 8.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  40 MISPPQTPENADEMSPDAFLASVEKDAKERAKRRRENRVLADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTN 119
Cdd:COG3914     4 AALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLEL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393 120 RAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAHVALKNYSKAKECYQKIEEINPKLkAQVkeHLNQ-VTLREKA 198
Cdd:COG3914    84 AALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDF-AEA--YLNLgEALRRLG 160


                  ....
gi 1720431393 199 DLQE 202
Cdd:COG3914   161 RLEE 164
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 79-179 3.69e-06

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 49.98  E-value: 3.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  79 LADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAH 158
Cdd:TIGR00990 330 EAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLH 409

                          90       100
                  ....*....|....*....|.
gi 1720431393 159 VALKNYSKAKECYQKIEEINP 179
Cdd:TIGR00990 410 FIKGEFAQAGKDYQKSIDLDP 430
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 79-210 2.89e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.95  E-value: 2.89e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  79 LADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAH 158
Cdd:COG5010    19 KLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLY 98

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1720431393 159 VALKNYSKAKECYQKIEEINPKLkAQVKEHLNQVTLREKadlQEKEAQESLD 210
Cdd:COG5010    99 SRSGDKDEAKEYYEKALALSPDN-PNAYSNLAALLLSLG---QDDEAKAALQ 146
TPR_1 pfam00515
Tetratricopeptide repeat;
149-180 3.23e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 41.25  E-value: 3.23e-05
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1720431393 149 KAYFHMGKAHVALKNYSKAKECYQKIEEINPK 180
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 85-210 5.40e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.49  E-value: 5.40e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  85 EKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAHVALKNY 164
Cdd:COG2956    13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLL 92

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1720431393 165 SKAKECYQKIEEINPKlkaqvkehlNQVTLREKADL--QEKEAQESLD 210
Cdd:COG2956    93 DRAEELLEKLLELDPD---------DAEALRLLAEIyeQEGDWEKAIE 131
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 149-180 8.89e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 40.12  E-value: 8.89e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1720431393  149 KAYFHMGKAHVALKNYSKAKECYQKIEEINPK 180
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_1 pfam00515
Tetratricopeptide repeat;
117-147 1.18e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 39.71  E-value: 1.18e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1720431393 117 YTNRAQAFIKLGDYQKALVDCDWALKCDENC 147
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 117-147 1.51e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 39.35  E-value: 1.51e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1720431393  117 YTNRAQAFIKLGDYQKALVDCDWALKCDENC 147
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 89-192 2.19e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.13  E-value: 2.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393  89 EAFVRGDYETAIFFYSEGLGKLKD----MKVLYtNRAQAFIKLGDYQKALVDCDWALKCDENCTK---AYFHMGKAHVAL 161
Cdd:COG1729     2 ALLKAGDYDEAIAAFKAFLKRYPNsplaPDALY-WLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLEL 80

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1720431393 162 KNYSKAKECYQKIEEINPKLKA--QVKEHLNQV 192
Cdd:COG1729    81 GDYDKARATLEELIKKYPDSEAakEARARLARL 113
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 149-180 4.06e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 38.27  E-value: 4.06e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1720431393 149 KAYFHMGKAHVALKNYSKAKECYQKIEEINPK 180
Cdd:pfam07719   2 EALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_8 pfam13181
Tetratricopeptide repeat;
149-180 7.03e-04

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 37.38  E-value: 7.03e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1720431393 149 KAYFHMGKAHVALKNYSKAKECYQKIEEINPK 180
Cdd:pfam13181   2 EAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
123-210 8.63e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.00  E-value: 8.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720431393 123 AFIKLGDYQKALVDCDWALKCDENCTKAYFHMGKAHVALKNYSKAKEcYQKIEEINPKlKAQVKEHLNQVTLREKadlQE 202
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPN-NAEALLNLAELLLELG---DY 75


                  ....*...
gi 1720431393 203 KEAQESLD 210
Cdd:COG3063    76 DEALAYLE 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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