telomere repeats-binding bouquet formation protein 1 isoform X9 [Mus musculus]
Protein Classification
telomere repeats-binding bouquet formation protein 1( domain architecture ID 10184727)
telomere repeats-binding bouquet formation protein 1 (TERB1) is a meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| SANT_DMAP1_like | cd11658 | SANT/myb-like domain of Human Dna Methyltransferase 1 Associated Protein 1-like; These ... |
342-387 | 2.27e-21 | ||
SANT/myb-like domain of Human Dna Methyltransferase 1 Associated Protein 1-like; These proteins are members of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of the DNA-binding Myb domains and is found in a diverse set of proteins. : Pssm-ID: 212556 Cd Length: 46 Bit Score: 86.31 E-value: 2.27e-21
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| Name | Accession | Description | Interval | E-value | ||
| SANT_DMAP1_like | cd11658 | SANT/myb-like domain of Human Dna Methyltransferase 1 Associated Protein 1-like; These ... |
342-387 | 2.27e-21 | ||
SANT/myb-like domain of Human Dna Methyltransferase 1 Associated Protein 1-like; These proteins are members of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of the DNA-binding Myb domains and is found in a diverse set of proteins. Pssm-ID: 212556 Cd Length: 46 Bit Score: 86.31 E-value: 2.27e-21
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| Name | Accession | Description | Interval | E-value | ||
| SANT_DMAP1_like | cd11658 | SANT/myb-like domain of Human Dna Methyltransferase 1 Associated Protein 1-like; These ... |
342-387 | 2.27e-21 | ||
SANT/myb-like domain of Human Dna Methyltransferase 1 Associated Protein 1-like; These proteins are members of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of the DNA-binding Myb domains and is found in a diverse set of proteins. Pssm-ID: 212556 Cd Length: 46 Bit Score: 86.31 E-value: 2.27e-21
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| SANT_TRF | cd11660 | Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ... |
342-388 | 2.15e-06 | ||
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1. Pssm-ID: 212558 [Multi-domain] Cd Length: 50 Bit Score: 44.48 E-value: 2.15e-06
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