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Conserved domains on  [gi|1370458520|ref|XP_024304050|]
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protein GVQW3 isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HTH_48 super family cl39372
HTH domain in Mos1 transposase; The N-terminal domain of the Mos1 Mariner transposase ...
 9-53 9.56e-08

HTH domain in Mos1 transposase; The N-terminal domain of the Mos1 Mariner transposase comprises two HTH domains. This HTH domain binds in the DNA major groove to the transposons inverted repeats.


The actual alignment was detected with superfamily member pfam17906:

Pssm-ID: 465558 [Multi-domain]  Cd Length: 50  Bit Score: 45.97  E-value: 9.56e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1370458520   9 RISIKFCVKLNKSASETHHLLKEAYGDEVMSRARVFDWHKRFKEG 53
Cdd:pfam17906   5 RHCILYEFLQGKSAAEAYRNICEVYGEDAVSERTFQRWFARFRSG 49
HTH_32 pfam13565
Homeodomain-like domain;
43-108 1.02e-04

Homeodomain-like domain;


:

Pssm-ID: 463923 [Multi-domain]  Cd Length: 73  Bit Score: 38.82  E-value: 1.02e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370458520  43 VFDWHKRFKE-GREDVRDDARSGRPvtHRTDDN-IQKVKDLVCSNRQLTVRMMAEELNLD------KETVRLIL 108
Cdd:pfam13565   2 VYRWRKRYNEeGLEGLEDRPRRGRP--RKLTDEqEARLLALLCEEPRWSPRLLAERLEEEfgvkvsRSTVRRIL 73
 
Name Accession Description Interval E-value
HTH_48 pfam17906
HTH domain in Mos1 transposase; The N-terminal domain of the Mos1 Mariner transposase ...
 9-53 9.56e-08

HTH domain in Mos1 transposase; The N-terminal domain of the Mos1 Mariner transposase comprises two HTH domains. This HTH domain binds in the DNA major groove to the transposons inverted repeats.


Pssm-ID: 465558 [Multi-domain]  Cd Length: 50  Bit Score: 45.97  E-value: 9.56e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1370458520   9 RISIKFCVKLNKSASETHHLLKEAYGDEVMSRARVFDWHKRFKEG 53
Cdd:pfam17906   5 RHCILYEFLQGKSAAEAYRNICEVYGEDAVSERTFQRWFARFRSG 49
HTH_32 pfam13565
Homeodomain-like domain;
43-108 1.02e-04

Homeodomain-like domain;


Pssm-ID: 463923 [Multi-domain]  Cd Length: 73  Bit Score: 38.82  E-value: 1.02e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370458520  43 VFDWHKRFKE-GREDVRDDARSGRPvtHRTDDN-IQKVKDLVCSNRQLTVRMMAEELNLD------KETVRLIL 108
Cdd:pfam13565   2 VYRWRKRYNEeGLEGLEDRPRRGRP--RKLTDEqEARLLALLCEEPRWSPRLLAERLEEEfgvkvsRSTVRRIL 73
 
Name Accession Description Interval E-value
HTH_48 pfam17906
HTH domain in Mos1 transposase; The N-terminal domain of the Mos1 Mariner transposase ...
 9-53 9.56e-08

HTH domain in Mos1 transposase; The N-terminal domain of the Mos1 Mariner transposase comprises two HTH domains. This HTH domain binds in the DNA major groove to the transposons inverted repeats.


Pssm-ID: 465558 [Multi-domain]  Cd Length: 50  Bit Score: 45.97  E-value: 9.56e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1370458520   9 RISIKFCVKLNKSASETHHLLKEAYGDEVMSRARVFDWHKRFKEG 53
Cdd:pfam17906   5 RHCILYEFLQGKSAAEAYRNICEVYGEDAVSERTFQRWFARFRSG 49
HTH_32 pfam13565
Homeodomain-like domain;
43-108 1.02e-04

Homeodomain-like domain;


Pssm-ID: 463923 [Multi-domain]  Cd Length: 73  Bit Score: 38.82  E-value: 1.02e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370458520  43 VFDWHKRFKE-GREDVRDDARSGRPvtHRTDDN-IQKVKDLVCSNRQLTVRMMAEELNLD------KETVRLIL 108
Cdd:pfam13565   2 VYRWRKRYNEeGLEGLEDRPRRGRP--RKLTDEqEARLLALLCEEPRWSPRLLAERLEEEfgvkvsRSTVRRIL 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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