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Conserved domains on  [gi|1370457300|ref|XP_024303819|]
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outer dynein arm-docking complex subunit 2 isoform X1 [Homo sapiens]

Protein Classification

HEAT repeat domain-containing protein( domain architecture ID 11444215)

HEAT repeat domain-containing protein similar to Homo sapiens deoxyhypusine hydroxylase (DOHH), which catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor

CATH:  1.25.10.10
Gene Ontology:  GO:0005515
PubMed:  10378263
SCOP:  4001283

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
883-1033 9.59e-08

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 51.94  E-value: 9.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  883 VRLLWSLLKNPHPDVKASAAWALcpciknakdaGEMVRSfvGGLELIVNLLKSDNKEVLASVCAAITNIAKDQenlavit 962
Cdd:COG1413     18 VPALIAALADEDPDVRAAAARAL----------GRLGDP--RAVPALLEALKDPDPEVRAAAAEALGRIGDPE------- 78

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370457300  963 dhgVVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQL 1033
Cdd:COG1413     79 ---AVPALIAALKDEDPEVRRAAAEALGR----------LGDPAAVPALLEALKDPDWEVRRAAARALGRL 136
HEAT COG1413
HEAT repeat [General function prediction only];
627-782 6.31e-06

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 46.93  E-value: 6.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  627 AIRKAGGIPLLARLLKTSHENMLIPVVGTLqecaseenyrAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKet 706
Cdd:COG1413     11 RLGDPAAVPALIAALADEDPDVRAAAARAL----------GRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPE-- 78

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370457300  707 rdlvrlhgGLKPLASLLNNTDNKERLAAVTGaiwkcsiskenVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGE 782
Cdd:COG1413     79 --------AVPALIAALKDEDPEVRRAAAEA-----------LGRLGDPAAVPALLEALKDPDWEVRRAAARALGR 135
PLN03200 super family cl33659
cellulose synthase-interactive protein; Provisional
 449-684 1.00e-03

cellulose synthase-interactive protein; Provisional


The actual alignment was detected with superfamily member PLN03200:

Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 43.55  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  449 SEYWQ---IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEvkCKIGSLKILKEISHNP 525
Cdd:PLN03200  1644 SEYYFevpVAVLVKLLRSTSESTVVVALNALLVLERDDSSSAEQMAESGAIEALLELLRSHQ--CEEAAARLLEALFNNV 1721

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  526 QIRQ-NIVDLGGLPIMVNILDsPH---KSLKCLAAETIANVAkfkrarrvvrQHGGITKlvalldcAHDSTKP--AQSSL 599
Cdd:PLN03200  1722 KVREmKATKYAIAPLSQYLLD-PQtrsQQARLLAALALGDLF----------QHEGLAR-------STDAVSAcrALVSL 1783

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  600 YEARDVE----VARCGALALWSCSKshTNKEAIRKAGGIPLLARLLKTSHEN------MLIPVV---GTLQECASEENYR 666
Cdd:PLN03200  1784 LEDQPTEemkmVAICALQNLVMHSR--TNKRAVAEAGGVQVVQELLLSSNPDtsgqaaLLIKLLfsnHTIQEYASSELIR 1861

                          250       260
                   ....*....|....*....|....*.
gi 1370457300  667 ---AAIKAE-----RIIENLVKNLNS 684
Cdd:PLN03200  1862 altAALEKDlwstaTVNEEVLRALNV 1887
 
Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
883-1033 9.59e-08

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 51.94  E-value: 9.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  883 VRLLWSLLKNPHPDVKASAAWALcpciknakdaGEMVRSfvGGLELIVNLLKSDNKEVLASVCAAITNIAKDQenlavit 962
Cdd:COG1413     18 VPALIAALADEDPDVRAAAARAL----------GRLGDP--RAVPALLEALKDPDPEVRAAAAEALGRIGDPE------- 78

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370457300  963 dhgVVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQL 1033
Cdd:COG1413     79 ---AVPALIAALKDEDPEVRRAAAEALGR----------LGDPAAVPALLEALKDPDWEVRRAAARALGRL 136
HEAT COG1413
HEAT repeat [General function prediction only];
627-782 6.31e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 46.93  E-value: 6.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  627 AIRKAGGIPLLARLLKTSHENMLIPVVGTLqecaseenyrAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKet 706
Cdd:COG1413     11 RLGDPAAVPALIAALADEDPDVRAAAARAL----------GRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPE-- 78

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370457300  707 rdlvrlhgGLKPLASLLNNTDNKERLAAVTGaiwkcsiskenVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGE 782
Cdd:COG1413     79 --------AVPALIAALKDEDPEVRRAAAEA-----------LGRLGDPAAVPALLEALKDPDWEVRRAAARALGR 135
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 885-990 2.18e-04

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 41.17  E-value: 2.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  885 LLWSLLKNPHPDVKASAAWALCPCikNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDH 964
Cdd:pfam13646    4 LLQALLRDPDPEVRAAAIRALGRI--GDPEA----------VPALLELLKDEDPAVRRAAAEA----------LGKIGDP 61

                           90       100
                   ....*....|....*....|....*..
gi 1370457300  965 GVVPLLSKLANTNNNK-LRHHLAEAIS 990
Cdd:pfam13646   62 EALPALLELLRDDDDDvVRAAAAEALA 88
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 624-661 6.42e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 38.20  E-value: 6.42e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1370457300  624 NKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECAS 661
Cdd:pfam00514    4 NKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 449-684 1.00e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 43.55  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  449 SEYWQ---IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEvkCKIGSLKILKEISHNP 525
Cdd:PLN03200  1644 SEYYFevpVAVLVKLLRSTSESTVVVALNALLVLERDDSSSAEQMAESGAIEALLELLRSHQ--CEEAAARLLEALFNNV 1721

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  526 QIRQ-NIVDLGGLPIMVNILDsPH---KSLKCLAAETIANVAkfkrarrvvrQHGGITKlvalldcAHDSTKP--AQSSL 599
Cdd:PLN03200  1722 KVREmKATKYAIAPLSQYLLD-PQtrsQQARLLAALALGDLF----------QHEGLAR-------STDAVSAcrALVSL 1783

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  600 YEARDVE----VARCGALALWSCSKshTNKEAIRKAGGIPLLARLLKTSHEN------MLIPVV---GTLQECASEENYR 666
Cdd:PLN03200  1784 LEDQPTEemkmVAICALQNLVMHSR--TNKRAVAEAGGVQVVQELLLSSNPDtsgqaaLLIKLLfsnHTIQEYASSELIR 1861

                          250       260
                   ....*....|....*....|....*.
gi 1370457300  667 ---AAIKAE-----RIIENLVKNLNS 684
Cdd:PLN03200  1862 altAALEKDlwstaTVNEEVLRALNV 1887
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 524-563 1.95e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 37.05  E-value: 1.95e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1370457300  524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA 563
Cdd:pfam00514    1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 621-656 2.39e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 36.64  E-value: 2.39e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1370457300   621 SHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTL 656
Cdd:smart00185    1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWAL 36
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 625-823 2.76e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 42.01  E-value: 2.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  625 KEAIRKAGGIPLLARLLKT----SHENMLIpVVGTLqeCASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQC 700
Cdd:PLN03200   481 KWAITAAGGIPPLVQLLETgsqkAKEDSAT-VLWNL--CCHSEDIRACVESAGAVPALLWLLKNGGPKGQEIAAKTLTKL 557

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  701 AEDKETRDLVRLhgglkpLASLLNNT-DNKERLAAVTGAIWkCSISKENVtkFRE----YKAIETLVGLLTDQPEEVLVN 775
Cdd:PLN03200   558 VRTADAATISQL------TALLLGDLpESKVHVLDVLGHVL-SVASLEDL--VREgsaaNDALRTLIQLLSSSKEETQEK 628

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370457300  776 VVGALGECCQERENrvivrKCGG------IQPLVNLLVGINQALLVNVTKAVGA 823
Cdd:PLN03200   629 AASVLADIFSSRQD-----LCESlatdeiINPCIKLLTNNTEAVATQSARALAA 677
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 924-953 8.13e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.10  E-value: 8.13e-03
                            10        20        30
                    ....*....|....*....|....*....|
gi 1370457300   924 GGLELIVNLLKSDNKEVLASVCAAITNIAK 953
Cdd:smart00185   12 GGLPALVELLKSEDEEVVKEAAWALSNLSS 41
 
Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
883-1033 9.59e-08

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 51.94  E-value: 9.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  883 VRLLWSLLKNPHPDVKASAAWALcpciknakdaGEMVRSfvGGLELIVNLLKSDNKEVLASVCAAITNIAKDQenlavit 962
Cdd:COG1413     18 VPALIAALADEDPDVRAAAARAL----------GRLGDP--RAVPALLEALKDPDPEVRAAAAEALGRIGDPE------- 78

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370457300  963 dhgVVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQL 1033
Cdd:COG1413     79 ---AVPALIAALKDEDPEVRRAAAEALGR----------LGDPAAVPALLEALKDPDWEVRRAAARALGRL 136
HEAT COG1413
HEAT repeat [General function prediction only];
627-782 6.31e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 46.93  E-value: 6.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  627 AIRKAGGIPLLARLLKTSHENMLIPVVGTLqecaseenyrAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKet 706
Cdd:COG1413     11 RLGDPAAVPALIAALADEDPDVRAAAARAL----------GRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPE-- 78

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370457300  707 rdlvrlhgGLKPLASLLNNTDNKERLAAVTGaiwkcsiskenVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGE 782
Cdd:COG1413     79 --------AVPALIAALKDEDPEVRRAAAEA-----------LGRLGDPAAVPALLEALKDPDWEVRRAAARALGR 135
HEAT COG1413
HEAT repeat [General function prediction only];
897-1037 7.73e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 46.55  E-value: 7.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  897 VKASAAWALCpcIKNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDHGVVPLLSKLANT 976
Cdd:COG1413      1 VRRAAARALG--RLGDPAA----------VPALIAALADEDPDVRAAAARA----------LGRLGDPRAVPALLEALKD 58

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370457300  977 NNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDA 1037
Cdd:COG1413     59 PDPEVRAAAAEALGR----------IGDPEAVPALIAALKDEDPEVRRAAAEALGRLGDPA 109
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 885-990 2.18e-04

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 41.17  E-value: 2.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  885 LLWSLLKNPHPDVKASAAWALCPCikNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDH 964
Cdd:pfam13646    4 LLQALLRDPDPEVRAAAIRALGRI--GDPEA----------VPALLELLKDEDPAVRRAAAEA----------LGKIGDP 61

                           90       100
                   ....*....|....*....|....*..
gi 1370457300  965 GVVPLLSKLANTNNNK-LRHHLAEAIS 990
Cdd:pfam13646   62 EALPALLELLRDDDDDvVRAAAAEALA 88
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 624-661 6.42e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 38.20  E-value: 6.42e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1370457300  624 NKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECAS 661
Cdd:pfam00514    4 NKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 449-684 1.00e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 43.55  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  449 SEYWQ---IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEvkCKIGSLKILKEISHNP 525
Cdd:PLN03200  1644 SEYYFevpVAVLVKLLRSTSESTVVVALNALLVLERDDSSSAEQMAESGAIEALLELLRSHQ--CEEAAARLLEALFNNV 1721

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  526 QIRQ-NIVDLGGLPIMVNILDsPH---KSLKCLAAETIANVAkfkrarrvvrQHGGITKlvalldcAHDSTKP--AQSSL 599
Cdd:PLN03200  1722 KVREmKATKYAIAPLSQYLLD-PQtrsQQARLLAALALGDLF----------QHEGLAR-------STDAVSAcrALVSL 1783

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  600 YEARDVE----VARCGALALWSCSKshTNKEAIRKAGGIPLLARLLKTSHEN------MLIPVV---GTLQECASEENYR 666
Cdd:PLN03200  1784 LEDQPTEemkmVAICALQNLVMHSR--TNKRAVAEAGGVQVVQELLLSSNPDtsgqaaLLIKLLfsnHTIQEYASSELIR 1861

                          250       260
                   ....*....|....*....|....*.
gi 1370457300  667 ---AAIKAE-----RIIENLVKNLNS 684
Cdd:PLN03200  1862 altAALEKDlwstaTVNEEVLRALNV 1887
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 524-563 1.95e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 37.05  E-value: 1.95e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 1370457300  524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA 563
Cdd:pfam00514    1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 928-1030 2.39e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.09  E-value: 2.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  928 LIVNLLKSDNKEVLASVCAAITNIaKDQEnlavitdhgVVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEHKA 1007
Cdd:pfam13646    4 LLQALLRDPDPEVRAAAIRALGRI-GDPE---------AVPALLELLKDEDPAVRRAAAEALGK----------IGDPEA 63

                           90       100
                   ....*....|....*....|....
gi 1370457300 1008 VAPLVRYLKS-NDTNVHRATAQAL 1030
Cdd:pfam13646   64 LPALLELLRDdDDDVVRAAAAEAL 87
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 621-656 2.39e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 36.64  E-value: 2.39e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 1370457300   621 SHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTL 656
Cdd:smart00185    1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWAL 36
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 625-823 2.76e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 42.01  E-value: 2.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  625 KEAIRKAGGIPLLARLLKT----SHENMLIpVVGTLqeCASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQC 700
Cdd:PLN03200   481 KWAITAAGGIPPLVQLLETgsqkAKEDSAT-VLWNL--CCHSEDIRACVESAGAVPALLWLLKNGGPKGQEIAAKTLTKL 557

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370457300  701 AEDKETRDLVRLhgglkpLASLLNNT-DNKERLAAVTGAIWkCSISKENVtkFRE----YKAIETLVGLLTDQPEEVLVN 775
Cdd:PLN03200   558 VRTADAATISQL------TALLLGDLpESKVHVLDVLGHVL-SVASLEDL--VREgsaaNDALRTLIQLLSSSKEETQEK 628

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370457300  776 VVGALGECCQERENrvivrKCGG------IQPLVNLLVGINQALLVNVTKAVGA 823
Cdd:PLN03200   629 AASVLADIFSSRQD-----LCESlatdeiINPCIKLLTNNTEAVATQSARALAA 677
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 924-953 8.13e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.10  E-value: 8.13e-03
                            10        20        30
                    ....*....|....*....|....*....|
gi 1370457300   924 GGLELIVNLLKSDNKEVLASVCAAITNIAK 953
Cdd:smart00185   12 GGLPALVELLKSEDEEVVKEAAWALSNLSS 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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