|
Name |
Accession |
Description |
Interval |
E-value |
| CNH |
smart00036 |
Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2; |
1176-1472 |
1.88e-78 |
|
Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2;
Pssm-ID: 214481 Cd Length: 302 Bit Score: 261.90 E-value: 1.88e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1176 DMNCTLPFSDQ--VVLVGTEEGLYALNVLK--NSLTHIPGIGAVFQIYIIKDLEKLLMIAGE---ERALCLVDVKKVKQS 1248
Cdd:smart00036 2 TAKWNHPITCDgkWLLVGTEEGLYVLNISDqpGTLEKLIGRRSVTQIWVLEENNVLLMISGKkpqLYSHPLSALVEKKEA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1249 LAQSHLPAQPDVSPNiFEAVKGCHLFAAGKIENSLCICAAMPSKVVIL-RYNDNLSKYCIR-----KEIETSEPCSCIHF 1322
Cdd:smart00036 82 LGSARLVIRKNVLTK-IPDVKGCHLCAVVNGKRSLFLCVALQSSVVLLqWYNPLKKFKLFKskflfPLISPVPVFVELVS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1323 TNY---SILIGTNKfYEIDMKQYTLDeFLDKNDHSLAPAVFASSSNSFPVSIVQANsagqreEYLLCFHEFGVFVDSYG- 1398
Cdd:smart00036 161 SSFerpGICIGSDK-GGGDVVQFHES-LVSKEDLSLPFLSEETSLKPISVVQVPRD------EVLLCYDEFGVFVNLYGk 232
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770412 1399 RRSRTDDLKWSRLPLAFAYREPYLFVTHFNSLEVIEIQARSSLGSPARAylEIPNPRYLGPaiSSGAIYLASSY 1472
Cdd:smart00036 233 RRSRNPILHWEFMPESFAYHSPYLLAFHDNGIEIRSIKTGELLQELADR--ETRKIRLLGS--SDRKILLSSSP 302
|
|
| CNH |
pfam00780 |
CNH domain; Domain found in NIK1-like kinase, mouse citron and yeast ROM1, ROM2. Unpublished ... |
1184-1436 |
6.11e-68 |
|
CNH domain; Domain found in NIK1-like kinase, mouse citron and yeast ROM1, ROM2. Unpublished observations.
Pssm-ID: 459938 Cd Length: 261 Bit Score: 229.83 E-value: 6.11e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1184 SDQVVLVGTEEGLYALNV-LKNSLTHIPGIGAVFQIYIIKDLEKLLMIAGEERALCLVDVKkvkqSLAQSHLPAQPDVSP 1262
Cdd:pfam00780 1 GGQNLLLGTEEGLYVLNRsGPREPVRIIDKKRVTQLAVLEEFNLLLLLSGKDKRLYVYPLS----ALDSREENDRKDAAK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1263 NIFEAVKGCHLFAAGKIENSLCICAAMPSKVVILRYNDNLS-KYCIRKEIETSEPCSCIHFTNYSILIGTNKFYE-IDMK 1340
Cdd:pfam00780 77 NKLPETKGCHFFKVGRHSNGRFLVVAVKRTIKLLEWYEPLLdKFRKFKEFYLPSPPVSIELLKSKLCVGCAKGFEiVSLD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1341 QYTLDEFLdkndhsLAPAVFASSSNSFPVSIVQANsagqREEYLLCFHEFGVFVDSYGRRSRTDDLKWSRLPLAFAYREP 1420
Cdd:pfam00780 157 SKATESLL------TSLLFANRQENLKPLAVVRLD----RSEFLLCYNEFGVYVNLQGRRSRPWEIEWEGAPEAVAYLYP 226
|
250
....*....|....*.
gi 1039770412 1421 YLFVTHFNSLEVIEIQ 1436
Cdd:pfam00780 227 YLLAFHDNFIEIRDVE 242
|
|
| CRIK |
cd20814 |
protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) ... |
927-982 |
3.82e-38 |
|
protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins; CRIK, also called serine/threonine-protein kinase 21, is an effector of the small GTPase Rho. It plays an important function during cytokinesis and affects its contractile process. CRIK-deficient mice show severe ataxia and epilepsy as a result of abnormal cytokinesis and massive apoptosis in neuronal precursors. A Down syndrome critical region protein TTC3 interacts with CRIK and inhibits CRIK-dependent neuronal differentiation and neurite extension. CRIK contains a catalytic domain, a central coiled-coil domain, and a C-terminal region containing a Rho-binding domain (RBD), a zinc finger (C1 domain), and a pleckstrin homology (PH) domain, in addition to other motifs. This model corresponds to C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410364 Cd Length: 56 Bit Score: 136.61 E-value: 3.82e-38
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 927 HNIPHRFNVGLNMRATKCAVCLDTVHFGRQASKCLECQVMCHPKCSTCLPATCGLP 982
Cdd:cd20814 1 HNIPHRFTTGLNMRATKCAVCLDGVPFGRQASKCSECGIVCHPKCSSSLPNTCGLP 56
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
72-869 |
2.52e-26 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 117.85 E-value: 2.52e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 72 EDDKALQLLHDIREQSRKLQEIKEQ--------------EYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAA 137
Cdd:TIGR02168 197 ELERQLKSLERQAEKAERYKELKAElrelelallvlrleELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 138 EEFKRKANECQHKLmkakdqgkpevgeYSKLEKINAEQQlKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKL 217
Cdd:TIGR02168 277 SELEEEIEELQKEL-------------YALANEISRLEQ-QKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 218 hnredssegiKKKLVEAEERRHSLENKVKRLEtMERREnrLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHL 297
Cdd:TIGR02168 343 ----------EEKLEELKEELESLEAELEELE-AELEE--LESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 298 KQKEQHYEEkikvLDNQIKKdlADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEAnklaans 377
Cdd:TIGR02168 410 ERLEDRRER----LQQEIEE--LLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQA------- 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 378 slftqrnMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKiSHQDHSDKSRLLEL-------ETRLrEVSLEHEE 450
Cdd:TIGR02168 477 -------LDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN-QSGLSGILGVLSELisvdegyEAAI-EAALGGRL 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 451 QKLELKRQLTELQL--SLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTV 528
Cdd:TIGR02168 548 QAVVVENLNAAKKAiaFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV 627
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 529 ITDLEEQLNQLTEDNAELNnqNFYLSKQLDEASG--------ANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKT 600
Cdd:TIGR02168 628 VDDLDNALELAKKLRPGYR--IVTLDGDLVRPGGvitggsakTNSSILERRREIEELEEKIEELEEKIAELEKALAELRK 705
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 601 TCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQvvelAVKEHK 680
Cdd:TIGR02168 706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE----ELAEAE 781
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 681 AEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLE--------TERELkQRLLEEQAKLQQQMDLQKNH 752
Cdd:TIGR02168 782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLEslerriaaTERRL-EDLEEQIEELSEDIESLAAE 860
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 753 IFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDqpaKKKKVPLQYNELKLA 832
Cdd:TIGR02168 861 IEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE---KLAQLELRLEGLEVR 937
|
810 820 830 840
....*....|....*....|....*....|....*....|
gi 1039770412 833 LEKEKARCAE---LEEALQKTRIELRSAREEAAHRKATDH 869
Cdd:TIGR02168 938 IDNLQERLSEeysLTLEEAEALENKIEDDEEEARRRLKRL 977
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
9-785 |
2.72e-24 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 111.30 E-value: 2.72e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 9 MEQEMTRLHRRVSEVEAVL----SQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVsqedDKALQLLHDIR 84
Cdd:TIGR02168 184 TRENLDRLEDILNELERQLksleRQAEKAERYKELKAELRELELALLVLRLEELREELEELQEEL----KEAEEELEELT 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 85 EQSrklqeikeQEYQAQVEEMRLMMNQLEEDLVSARRRsdLYeselresrlaaeEFKRKANECQHKLMKAKDQGKPEVGE 164
Cdd:TIGR02168 260 AEL--------QELEEKLEELRLEVSELEEEIEELQKE--LY------------ALANEISRLEQQKQILRERLANLERQ 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 165 YSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNR----EDSSEGIKKKLVEAEERRHS 240
Cdd:TIGR02168 318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRleelEEQLETLRSKVAQLELQIAS 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 241 LENKVKRLET----MERRENRLKDDIQTKSEQIQ--QMADKILELEEKHREAQVSAQHLEVH------LKQKEQHYEEKI 308
Cdd:TIGR02168 398 LNNEIERLEArlerLEDRRERLQQEIEELLKKLEeaELKELQAELEELEEELEELQEELERLeealeeLREELEEAEQAL 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 309 KVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAM---INAMDSKIRSLEQRIVELSEAnkLAANSSLFTQRNM 385
Cdd:TIGR02168 478 DAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgiLGVLSELISVDEGYEAAIEAA--LGGRLQAVVVENL 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 386 KAQEEMISELRQQK-----FYLETQAGKLEAQNRKLEE------------QLEKISHQDHSDKSRLL------------- 435
Cdd:TIGR02168 556 NAAKKAIAFLKQNElgrvtFLPLDSIKGTEIQGNDREIlkniegflgvakDLVKFDPKLRKALSYLLggvlvvddldnal 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 436 ----ELETRLREVSLEHE----------------------EQKL-ELKRQLTELQLSLQERESQLTALQAARAALESQLR 488
Cdd:TIGR02168 636 elakKLRPGYRIVTLDGDlvrpggvitggsaktnssilerRREIeELEEKIEELEEKIAELEKALAELRKELEELEEELE 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 489 QAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQnfyLSKQLDEASGANDEIV 568
Cdd:TIGR02168 716 QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE---LAEAEAEIEELEAQIE 792
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 569 QLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQ 648
Cdd:TIGR02168 793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 649 RMLDTEKQSRARADQRITESR---QVVELAVKEHKAEILALQQALKEqklkaesLSDKLNDLEKKHAMLEMNARSLQQKL 725
Cdd:TIGR02168 873 SELEALLNERASLEEALALLRselEELSEELRELESKRSELRRELEE-------LREKLAQLELRLEGLEVRIDNLQERL 945
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770412 726 eteRELKQRLLEEQAKLQQQMDLQ----KNHIFRLTQGLQE-------ALD-------RADLLKTERSDLEYQLENIQ 785
Cdd:TIGR02168 946 ---SEEYSLTLEEAEALENKIEDDeeeaRRRLKRLENKIKElgpvnlaAIEeyeelkeRYDFLTAQKEDLTEAKETLE 1020
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
174-862 |
3.80e-23 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 107.45 E-value: 3.80e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 174 EQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEkLHNREDSSEG--IKKKLVEAEERRHSLENKVKRletM 251
Cdd:TIGR02168 176 ETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKE-LKAELRELELalLVLRLEELREELEELQEELKE---A 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 252 ERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQ---VSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKESLENM 328
Cdd:TIGR02168 252 EEELEELTAELQELEEKLEELRLEVSELEEEIEELQkelYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 329 MQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKlaansslftqrnmkAQEEMISELRQQKFYLETQAGK 408
Cdd:TIGR02168 332 LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLE--------------ELEEQLETLRSKVAQLELQIAS 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 409 LEAQNRKLEEQLEKISHQDHSDKSRLLELETRLrevsleHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLR 488
Cdd:TIGR02168 398 LNNEIERLEARLERLEDRRERLQQEIEELLKKL------EEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 489 QAKteleettaeaeeeiQALTAHRDEIQRkfdaLRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASgandEIV 568
Cdd:TIGR02168 472 EAE--------------QALDAAERELAQ----LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS----ELI 529
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 569 QLRSEV---------DHLRREITERemqLTSQKQTMEALK----TTCTMLEEQVL---DLEALNDELLEKERQWEAWRSV 632
Cdd:TIGR02168 530 SVDEGYeaaieaalgGRLQAVVVEN---LNAAKKAIAFLKqnelGRVTFLPLDSIkgtEIQGNDREILKNIEGFLGVAKD 606
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 633 LGDEKSQFEcrvRELQRMLD-----------TEKQSRARADQRIT-------ESRQVVELAVKEHKAEILALQQALKEQK 694
Cdd:TIGR02168 607 LVKFDPKLR---KALSYLLGgvlvvddldnaLELAKKLRPGYRIVtldgdlvRPGGVITGGSAKTNSSILERRREIEELE 683
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 695 LKAESLSDKLNDLEKKHAMLemnaRSLQQKLETERELKQRLLEEqakLQQQMDLQKNHIFRLTQGLQEALDRADLLKTER 774
Cdd:TIGR02168 684 EKIEELEEKIAELEKALAEL----RKELEELEEELEQLRKELEE---LSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 775 SDLEYQLEniqvlyshekvkmegtiSQQTKLIDFLQAKMDQPAKKKKVPLQYNELKLALEKEKARCAELEEALQKTRIEL 854
Cdd:TIGR02168 757 TELEAEIE-----------------ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA 819
|
....*...
gi 1039770412 855 RSAREEAA 862
Cdd:TIGR02168 820 ANLRERLE 827
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
173-784 |
1.41e-22 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 105.40 E-value: 1.41e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 173 AEQQLKIQELQEKLEKAvkastEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEerrhslenkvKRLETME 252
Cdd:COG1196 209 AEKAERYRELKEELKEL-----EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE----------AELEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 253 RRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEvhlkQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRH 332
Cdd:COG1196 274 LELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE----ERLEELEEELAELEEELEELEEELEELEEELEEA 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 333 EEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQ 412
Cdd:COG1196 350 EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEA 429
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 413 NRKLEEQLEKISHQDHSDKSRLLELETR---LREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQ 489
Cdd:COG1196 430 LAELEEEEEEEEEALEEAAEEEAELEEEeeaLLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 490 AKTELEETTAEAEeeIQALTAHRDEIQRKFDALRnsctvitdleeqlnqlTEDNAELNNQNfylskqLDEASGANDEIVQ 569
Cdd:COG1196 510 VKAALLLAGLRGL--AGAVAVLIGVEAAYEAALE----------------AALAAALQNIV------VEDDEVAAAAIEY 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 570 LRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQR 649
Cdd:COG1196 566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR 645
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 650 MLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETER 729
Cdd:COG1196 646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 1039770412 730 ElKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENI 784
Cdd:COG1196 726 L-EEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2-737 |
6.62e-22 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 103.60 E-value: 6.62e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 2 LLGEEAMMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLH 81
Cdd:TIGR02168 244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEA 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 82 DIREQSRKLQEIKE---------QEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKLM 152
Cdd:TIGR02168 324 QLEELESKLDELAEelaeleeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 153 KAKDQGKPEVGEYSKLEKINAEQQ-----LKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGi 227
Cdd:TIGR02168 404 RLEARLERLEDRRERLQQEIEELLkkleeAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER- 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 228 kkKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKIlELEEKHREA-----QVSAQHLEV------- 295
Cdd:TIGR02168 483 --ELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELI-SVDEGYEAAieaalGGRLQAVVVenlnaak 559
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 296 ----HLKQKE----------QHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSL- 360
Cdd:TIGR02168 560 kaiaFLKQNElgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAk 639
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 361 ----EQRIVEL-----------SEANKLAANSSLFTQRN-------MKAQEEMISELRQQKFYLETQAGKLEAQNRKLEE 418
Cdd:TIGR02168 640 klrpGYRIVTLdgdlvrpggviTGGSAKTNSSILERRREieeleekIEELEEKIAELEKALAELRKELEELEEELEQLRK 719
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 419 QLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKR---QLTELQLSLQERESQLTALQAARAALESQLRQAKTELE 495
Cdd:TIGR02168 720 ELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEleaEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK 799
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 496 ETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNnqnfylskqlDEASGANDEIVQLRSEVD 575
Cdd:TIGR02168 800 ALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS----------EDIESLAAEIEELEELIE 869
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 576 HLRREITEREMQLTSQKQTMEALKTTctmLEEQVLDLEALNDELLEKERQWEAwrsvLGDEKSQFECRVRELQRMLDtEK 655
Cdd:TIGR02168 870 ELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRELEE----LREKLAQLELRLEGLEVRID-NL 941
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 656 QSRARADQRITEsrQVVELAVKEHKAEILALQQALK--EQKLKA------------ESLSDKLNDLEKKHAMLEMNARSL 721
Cdd:TIGR02168 942 QERLSEEYSLTL--EEAEALENKIEDDEEEARRRLKrlENKIKElgpvnlaaieeyEELKERYDFLTAQKEDLTEAKETL 1019
|
810
....*....|....*..
gi 1039770412 722 QQKL-ETERELKQRLLE 737
Cdd:TIGR02168 1020 EEAIeEIDREARERFKD 1036
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
236-796 |
3.45e-21 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 101.17 E-value: 3.45e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 236 ERRHSLENKvkrLETMERRENRLKDDIQTKSEQIQQMAD--------KILELEEKHREAQVSAQHLEvHLKQKEQHYEEK 307
Cdd:COG1196 172 ERKEEAERK---LEATEENLERLEDILGELERQLEPLERqaekaeryRELKEELKELEAELLLLKLR-ELEAELEELEAE 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 308 IKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAansslftQRNMKA 387
Cdd:COG1196 248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL-------EERLEE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 388 QEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVS----------LEHEEQKLELKR 457
Cdd:COG1196 321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEeeleelaeelLEALRAAAELAA 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 458 QLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLN 537
Cdd:COG1196 401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 538 QLTEDNAELNNQNFYLSKQLDEASGAND----------------EIVQLRSEVDHLRREITEREMQLTSQ---------K 592
Cdd:COG1196 481 ELLEELAEAAARLLLLLEAEADYEGFLEgvkaalllaglrglagAVAVLIGVEAAYEAALEAALAAALQNivveddevaA 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 593 QTMEALKTT----CTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITES 668
Cdd:COG1196 561 AAIEYLKAAkagrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 669 RQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDL 748
Cdd:COG1196 641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720
|
570 580 590 600
....*....|....*....|....*....|....*....|....*...
gi 1039770412 749 QKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKME 796
Cdd:COG1196 721 LEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
22-866 |
2.75e-19 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 95.04 E-value: 2.75e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 22 EVEAVLSQKEVElkasetqRSLLEQDLATYItecssLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQ 101
Cdd:pfam02463 143 KIEIIAMMKPER-------RLEIEEEAAGSR-----LKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKAL 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 102 VEEMRLMMNQLEEDLVSARRRSDLYESELRES----RLAAEEFKRKANECQHKLMKAKDQGKPEVGEYSKLEKINAEQQL 177
Cdd:pfam02463 211 EYYQLKEKLELEEEYLLYLDYLKLNEERIDLLqellRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKL 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 178 KIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSLENKVKRLETMERRENR 257
Cdd:pfam02463 291 LAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQ 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 258 LKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAH 337
Cdd:pfam02463 371 LEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEK 450
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 338 EKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYL--ETQAGKLEAQNRK 415
Cdd:pfam02463 451 EELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALikDGVGGRIISAHGR 530
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 416 LEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELE 495
Cdd:pfam02463 531 LGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDK 610
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 496 ETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVD 575
Cdd:pfam02463 611 ATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELA 690
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 576 HLRREITEREMQLTSQKQTMEALKTTCTMLE-EQVLDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTE 654
Cdd:pfam02463 691 KEEILRRQLEIKKKEQREKEELKKLKLEAEElLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELS 770
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 655 KQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQR 734
Cdd:pfam02463 771 LKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEK 850
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 735 LLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENiqvlysHEKVKMEGTISQQTKLIDFLQAKMD 814
Cdd:pfam02463 851 LAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEK------KELEEESQKLNLLEEKENEIEERIK 924
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|...
gi 1039770412 815 QPAKKKKVPLQYN-ELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKA 866
Cdd:pfam02463 925 EEAEILLKYEEEPeELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNL 977
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
9-581 |
5.55e-19 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 93.85 E-value: 5.55e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 9 MEQEMTRLHRRVSEVEAVLS----QKEV-----ELKASETQRSL---------LEQDLATYITECSSLKRSLEQARMEVS 70
Cdd:COG1196 184 TEENLERLEDILGELERQLEplerQAEKaeryrELKEELKELEAellllklreLEAELEELEAELEELEAELEELEAELA 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 71 QEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLmmnqlEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHK 150
Cdd:COG1196 264 ELEAELEELRLELEELELELEEAQAEEYELLAELARL-----EQDIARLEERRRELEERLEELEEELAELEEELEELEEE 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 151 LMKAKDQgkpevgeyskLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKK 230
Cdd:COG1196 339 LEELEEE----------LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 231 LVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQqmadkilELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKV 310
Cdd:COG1196 409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA-------EEEAELEEEEEALLELLAELLEEAALLEAALAE 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 311 LDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEE 390
Cdd:COG1196 482 LLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAA 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 391 MISELRQQK-----FYLETQAGKLEAQNRKLEEQLEK-----------------------------ISHQDHSDKSRLLE 436
Cdd:COG1196 562 AIEYLKAAKagratFLPLDKIRARAALAAALARGAIGaavdlvasdlreadaryyvlgdtllgrtlVAARLEAALRRAVT 641
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 437 LETRLREVSLEHEEQkleLKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQ 516
Cdd:COG1196 642 LAGRLREVTLEGEGG---SAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039770412 517 RKFDALRNSCTVITDLEEQLNQLTEDNAElnnqnfyLSKQLDEASGANDEIVQLRSEVDHLRREI 581
Cdd:COG1196 719 EELEEEALEEQLEAEREELLEELLEEEEL-------LEEEALEELPEPPDLEELERELERLEREI 776
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
200-785 |
8.88e-19 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 92.78 E-value: 8.88e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 200 LQNIRQAKERAERELEK--------LHNREDSSEGIKKKLVEAEERRHSLENKVKRLETmerRENRLKDDIQTKSEQIQQ 271
Cdd:TIGR04523 24 YKNIANKQDTEEKQLEKklktikneLKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQ---QIKDLNDKLKKNKDKINK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 272 M-AD-KILELEEKHREAQVSAQHLEV-HLKQKEQHYEEKIKVLDNQIKKDLAD--------------KESLENMMQRHEE 334
Cdd:TIGR04523 101 LnSDlSKINSEIKNDKEQKNKLEVELnKLEKQKKENKKNIDKFLTEIKKKEKEleklnnkyndlkkqKEELENELNLLEK 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 335 EAHEKGKILSEQKAMINAMD---SKIRSLEQRIVEL-SEANKL-AANSSLFTQRNMKAQEemISELRQQKFYLETQAGKL 409
Cdd:TIGR04523 181 EKLNIQKNIDKIKNKLLKLElllSNLKKKIQKNKSLeSQISELkKQNNQLKDNIEKKQQE--INEKTTEISNTQTQLNQL 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 410 EAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLE------------HEEQKLELK---RQLTELQLSLQERESQLT 474
Cdd:TIGR04523 259 KDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEisdlnnqkeqdwNKELKSELKnqeKKLEEIQNQISQNNKIIS 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 475 ALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQ--NFY 552
Cdd:TIGR04523 339 QLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQikKLQ 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 553 LSKQLDEASGAN--DEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQV----LDLEALNDELLEKERQW 626
Cdd:TIGR04523 419 QEKELLEKEIERlkETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSInkikQNLEQKQKELKSKEKEL 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 627 EAwrsvLGDEKSQFECRVRELqrmldTEKQSraradqritesrqvvELAVKEHKAEILALQqalKEQKLKaeSLSDKLN- 705
Cdd:TIGR04523 499 KK----LNEEKKELEEKVKDL-----TKKIS---------------SLKEKIEKLESEKKE---KESKIS--DLEDELNk 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 706 -DLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEAL-------DRADLLKTERSDL 777
Cdd:TIGR04523 550 dDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEkkissleKELEKAKKENEKL 629
|
....*...
gi 1039770412 778 EYQLENIQ 785
Cdd:TIGR04523 630 SSIIKNIK 637
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
79-709 |
9.89e-19 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 93.08 E-value: 9.89e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 79 LLHDIREQSRKLQEIKEQ--EYQAQVEEMRlmmnqleedlvsaRRRSDLYESELRESRLAAEEFKRKANECQhklmkakd 156
Cdd:COG1196 194 ILGELERQLEPLERQAEKaeRYRELKEELK-------------ELEAELLLLKLRELEAELEELEAELEELE-------- 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 157 qgkpevgeySKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEE 236
Cdd:COG1196 253 ---------AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 237 RRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIK 316
Cdd:COG1196 324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 317 KDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELR 396
Cdd:COG1196 404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 397 QQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLE------LKRQLTELQLSLQERE 470
Cdd:COG1196 484 EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEaalaaaLQNIVVEDDEVAAAAI 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 471 SQLTALQAARAA---LESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELN 547
Cdd:COG1196 564 EYLKAAKAGRATflpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLA 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 548 NQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEAlkttctMLEEQVLDLEALNDELLEKERQWE 627
Cdd:COG1196 644 GRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL------ELEEALLAEEEEERELAEAEEERL 717
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 628 AWRSVLGDEKSQFE-CRVRELQRMLDTEKQSRARADQRITE--SRQVVELAVKEHKAEI--------LALQQaLKEQKLK 696
Cdd:COG1196 718 EEELEEEALEEQLEaEREELLEELLEEEELLEEEALEELPEppDLEELERELERLEREIealgpvnlLAIEE-YEELEER 796
|
650
....*....|...
gi 1039770412 697 AESLSDKLNDLEK 709
Cdd:COG1196 797 YDFLSEQREDLEE 809
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
10-744 |
3.54e-18 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 91.19 E-value: 3.54e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 10 EQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDI--REQS 87
Cdd:pfam02463 264 EEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIeeLEKE 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 88 RKLQEIKEQEYQAQVEEMRLMM----NQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKLMKAKDQGKPEVG 163
Cdd:pfam02463 344 LKELEIKREAEEEEEEELEKLQekleQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKE 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 164 EYSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSLEN 243
Cdd:pfam02463 424 EKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKES 503
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 244 KVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKH-----REAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKd 318
Cdd:pfam02463 504 KARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVaistaVIVEVSATADEVEERQKLVRALTELPLGARKLRL- 582
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 319 LADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQ 398
Cdd:pfam02463 583 LIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKS 662
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 399 KFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQA 478
Cdd:pfam02463 663 EVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLK 742
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 479 ARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLD 558
Cdd:pfam02463 743 QKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQL 822
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 559 EASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKS 638
Cdd:pfam02463 823 LIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKEL 902
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 639 QFECRVRELQRMLDTEKQSR-ARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMN 717
Cdd:pfam02463 903 EEESQKLNLLEEKENEIEERiKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEE 982
|
730 740
....*....|....*....|....*..
gi 1039770412 718 ARSLQQKLETERELKQRLLEEQAKLQQ 744
Cdd:pfam02463 983 FEEKEERYNKDELEKERLEEEKKKLIR 1009
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
12-778 |
4.04e-18 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 91.36 E-value: 4.04e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 12 EMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQdlatyitecsslKRSLEQARMEVSQEDDKALQLLHDIR--EQSRK 89
Cdd:PTZ00121 1068 QDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEE------------AKKTETGKAEEARKAEEAKKKAEDARkaEEARK 1135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 90 LQEIKEQEYQAQVEEMRlmmnqleeDLVSARRRSDLYESElrESRLAAE----EFKRKANECQ--HKLMKAKDQGKPEvg 163
Cdd:PTZ00121 1136 AEDARKAEEARKAEDAK--------RVEIARKAEDARKAE--EARKAEDakkaEAARKAEEVRkaEELRKAEDARKAE-- 1203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 164 EYSKLEKINAEQQLKIQELQEKLEkAVKASTEATELLQNIRQA-KERAERELEKLHNREDSSEGIKKKLVEAEERRHSLE 242
Cdd:PTZ00121 1204 AARKAEEERKAEEARKAEDAKKAE-AVKKAEEAKKDAEEAKKAeEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE 1282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 243 NK----------------VKRLETMERR--ENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHY 304
Cdd:PTZ00121 1283 LKkaeekkkadeakkaeeKKKADEAKKKaeEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA 1362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 305 EEKIKVLD----------NQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVElsEANKLA 374
Cdd:PTZ00121 1363 EEKAEAAEkkkeeakkkaDAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD--EAKKKA 1440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 375 ANSSLFTQRNMKAQEEMISELRQQKfylETQAGKLEAQNRKLEE--QLEKISHQDHSDKSRLLELETRLREVSLEHEEQK 452
Cdd:PTZ00121 1441 EEAKKADEAKKKAEEAKKAEEAKKK---AEEAKKADEAKKKAEEakKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKK 1517
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 453 LELKRQLTELQLSLQERESqltalQAARAALEsqLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSctvitdl 532
Cdd:PTZ00121 1518 AEEAKKADEAKKAEEAKKA-----DEAKKAEE--KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA------- 1583
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 533 eEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEvdHLRREITEREMQLTSQKQTMEALKTTCTML---EEQV 609
Cdd:PTZ00121 1584 -EEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE--ELKKAEEEKKKVEQLKKKEAEEKKKAEELKkaeEENK 1660
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 610 LDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEkQSRARADQRITESRQVVElAVKEHKAEILALQQA 689
Cdd:PTZ00121 1661 IKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE-ELKKKEAEEKKKAEELKK-AEEENKIKAEEAKKE 1738
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 690 LKEQKLKAESLsdKLNDLEKK---HAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDR 766
Cdd:PTZ00121 1739 AEEDKKKAEEA--KKDEEEKKkiaHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
|
810
....*....|..
gi 1039770412 767 ADLLKTERSDLE 778
Cdd:PTZ00121 1817 GNLVINDSKEME 1828
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
33-849 |
8.12e-18 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 90.13 E-value: 8.12e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 33 ELKASETQRSLLEQDLAtyitecsSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRlmmnQL 112
Cdd:TIGR02169 231 EKEALERQKEAIERQLA-------SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIG----EL 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 113 EEDLVSARRRSDLYESELREsrlaAEEFKRKANECQHKLMKAKDQGKPEVGEYSKlekinaeqqlkiqeLQEKLEKAVKA 192
Cdd:TIGR02169 300 EAEIASLERSIAEKERELED----AEERLAKLEAEIDKLLAEIEELEREIEEERK--------------RRDKLTEEYAE 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 193 STEATELLQNIRQAKERAERELeklhnredssegiKKKLVEAEERrhsLENKVKRLETMERRENRLKDDIQTKSEQIQQM 272
Cdd:TIGR02169 362 LKEELEDLRAELEEVDKEFAET-------------RDELKDYREK---LEKLKREINELKRELDRLQEELQRLSEELADL 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 273 ADKILELEEKHREAQVSAQHLEVHLKQKEQHYEekikvldnQIKKDLADKEslenmmqrheeeahekgKILSEQKAMINA 352
Cdd:TIGR02169 426 NAAIAGIEAKINELEEEKEDKALEIKKQEWKLE--------QLAADLSKYE-----------------QELYDLKEEYDR 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 353 MDSKIRSLEQRIVELsEANKLAANSslfTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEE-----QLEKISHQD 427
Cdd:TIGR02169 481 VEKELSKLQRELAEA-EAQARASEE---RVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvaagnRLNNVVVED 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 428 HSDKSRLLELETR----------LREVSLEHEEQKLELKRQLTELQLSLQERESQLtalqaaRAALESQLRQAKTELEET 497
Cdd:TIGR02169 557 DAVAKEAIELLKRrkagratflpLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKY------EPAFKYVFGDTLVVEDIE 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 498 TAEAEEEIQALTAHRDEIQRK-------FDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEivqL 570
Cdd:TIGR02169 631 AARRLMGKYRMVTLEGELFEKsgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDE---L 707
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 571 RSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEqvlDLEALNDELLEKERQWEAWRSVLGD---EKSQFECRVREL 647
Cdd:TIGR02169 708 SQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEE---DLSSLEQEIENVKSELKELEARIEEleeDLHKLEEALNDL 784
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 648 QRMLDTEKQsraradQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLET 727
Cdd:TIGR02169 785 EARLSHSRI------PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEN 858
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 728 ERELKQRLLEEQAKLQQQmdlqknhifrltqgLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLID 807
Cdd:TIGR02169 859 LNGKKEELEEELEELEAA--------------LRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA 924
|
810 820 830 840
....*....|....*....|....*....|....*....|....*
gi 1039770412 808 FLQAKMDQPA---KKKKVPLQYNELKLALEKEKARCAELEEALQK 849
Cdd:TIGR02169 925 KLEALEEELSeieDPKGEDEEIPEEELSLEDVQAELQRVEEEIRA 969
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
83-627 |
2.23e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 85.12 E-value: 2.23e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 83 IREQSRKLQEIKEqeYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRkanecqhklmkakdqgkpev 162
Cdd:PRK03918 171 IKEIKRRIERLEK--FIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEK-------------------- 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 163 gEYSKLEKINAEqqlkIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSLE 242
Cdd:PRK03918 229 -EVKELEELKEE----IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYE 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 243 NKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVhLKQKEQHYEEKIKVLDN--QIKKDLA 320
Cdd:PRK03918 304 EYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE-LEERHELYEEAKAKKEEleRLKKRLT 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 321 DK--ESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEA-NKLAANSSLFTQRN----MKAQEEMIS 393
Cdd:PRK03918 383 GLtpEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAkGKCPVCGRELTEEHrkelLEEYTAELK 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 394 ELRQQKFYLETQAGKLEAQNRKLEEQLEKISH--QDHSDKSRLLELETRLREVSLEHEEQKLE----LKRQLTEL---QL 464
Cdd:PRK03918 463 RIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKKYNLEELEKKAEeyekLKEKLIKLkgeIK 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 465 SLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEE-----------IQALtahrDEIQRKFDALRNSCTVITDLE 533
Cdd:PRK03918 543 SLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesveeleerLKEL----EPFYNEYLELKDAEKELEREE 618
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 534 EQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDH--LRREITEREMQLTSQKQTMEALKTTCTMLEEQVLD 611
Cdd:PRK03918 619 KELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYeeLREEYLELSRELAGLRAELEELEKRREEIKKTLEK 698
|
570
....*....|....*.
gi 1039770412 612 LEALNDELLEKERQWE 627
Cdd:PRK03918 699 LKEELEEREKAKKELE 714
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
19-618 |
2.45e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 85.12 E-value: 2.45e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 19 RVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEqaRMEVSQEDDKALQLLHDIREQSRKLQEIKEQEY 98
Cdd:PRK03918 187 RTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK--ELEELKEEIEELEKELESLEGSKRKLEEKIREL 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 99 QAQVEEMRLMMNQLEEdlvSARRRSDLYESELRESRLaaEEFKRKANECQHKLMKakdqgkpevgEYSKLEKINAEQQLK 178
Cdd:PRK03918 265 EERIEELKKEIEELEE---KVKELKELKEKAEEYIKL--SEFYEEYLDELREIEK----------RLSRLEEEINGIEER 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 179 IQELQEKLEKAVKASTEATELLQNIRQAKERAErELEKLHNREDSSEGIKKKL--VEAEERRHSLENKVKRLETMERREN 256
Cdd:PRK03918 330 IKELEEKEERLEELKKKLKELEKRLEELEERHE-LYEEAKAKKEELERLKKRLtgLTPEKLEKELEELEKAKEEIEEEIS 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 257 RLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEvhlkqkEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEA 336
Cdd:PRK03918 409 KITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELT------EEHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 337 HEKGKILSEQKAMI--NAMDSKIRSLEQRIVELsEANKLAANSSLFTqrnmKAQEEMIsELRQQKFYLETQAGKLEAQNR 414
Cdd:PRK03918 483 RELEKVLKKESELIklKELAEQLKELEEKLKKY-NLEELEKKAEEYE----KLKEKLI-KLKGEIKSLKKELEKLEELKK 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 415 KLEEQLEKIshqdHSDKSRLLELETRLREVSLEHEEqklELKRQLTELQ------LSLQERESQLTALQAARAALESQLR 488
Cdd:PRK03918 557 KLAELEKKL----DELEEELAELLKELEELGFESVE---ELEERLKELEpfyneyLELKDAEKELEREEKELKKLEEELD 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 489 QAktelEETTAEAEEEIQALTAHRDEIQRKFDalrnsctvitdlEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIV 568
Cdd:PRK03918 630 KA----FEELAETEKRLEELRKELEELEKKYS------------EEEYEELREEYLELSRELAGLRAELEELEKRREEIK 693
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 1039770412 569 QLRSEVDHLRREITEREMQLTSQKQTMEALkttcTMLEEQVLDLEALNDE 618
Cdd:PRK03918 694 KTLEKLKEELEEREKAKKELEKLEKALERV----EELREKVKKYKALLKE 739
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
5-732 |
3.23e-16 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 85.12 E-value: 3.23e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 5 EEAMMEQEMTRLHRRVSEVEAVLSQ--KEVELKASETQRSLLEQdLATYITECSSLKRSLEQARMEVSQEDDKALQLLHD 82
Cdd:TIGR02169 252 ELEKLTEEISELEKRLEEIEQLLEElnKKIKDLGEEEQLRVKEK-IGELEAEIASLERSIAEKERELEDAEERLAKLEAE 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 83 IREQSRKLQEIKEQeyqaqVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKLMKAKDQGKPEV 162
Cdd:TIGR02169 331 IDKLLAEIEELERE-----IEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELK 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 163 GEYSKLEKINAEQQLKIQELQEKL----EKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERR 238
Cdd:TIGR02169 406 RELDRLQEELQRLSEELADLNAAIagieAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKEL 485
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 239 HSLENKVKRLETMER------RENR-----LKDDIQTKSEQIQQMadkiLELEEKHREAqvsaqhLEVHLKQKeqhyeek 307
Cdd:TIGR02169 486 SKLQRELAEAEAQARaseervRGGRaveevLKASIQGVHGTVAQL----GSVGERYATA------IEVAAGNR------- 548
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 308 ikvLDNQIKKDLADKESLENMMQRHE------------EEAHEKGKILSEQKAMINAMD--------------------- 354
Cdd:TIGR02169 549 ---LNNVVVEDDAVAKEAIELLKRRKagratflplnkmRDERRDLSILSEDGVIGFAVDlvefdpkyepafkyvfgdtlv 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 355 -----------SKIR--SLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKfyletqaGKLEAQNRKLEEQLE 421
Cdd:TIGR02169 626 vedieaarrlmGKYRmvTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERL-------EGLKRELSSLQSELR 698
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 422 KISHQDHSDKSRLLELETRLREVSLEHE--EQKLE-LKRQLTELQLSLQERESQLTALQAARAALESQLrQAKTELEETT 498
Cdd:TIGR02169 699 RIENRLDELSQELSDASRKIGEIEKEIEqlEQEEEkLKERLEELEEDLSSLEQEIENVKSELKELEARI-EELEEDLHKL 777
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 499 AEAEEEIQALTAHR--DEIQRKFDALRnscTVITDLEEQLNQLtedNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDH 576
Cdd:TIGR02169 778 EEALNDLEARLSHSriPEIQAELSKLE---EEVSRIEARLREI---EQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKS 851
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 577 LRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQ 656
Cdd:TIGR02169 852 IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEE 931
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 657 SRARADQRITESRQVVELA-----VKEHKAEILALQQALKEQKLKA----ESLSDKLNDLEKKHAMLEMNARSLQQKLET 727
Cdd:TIGR02169 932 ELSEIEDPKGEDEEIPEEElsledVQAELQRVEEEIRALEPVNMLAiqeyEEVLKRLDELKEKRAKLEEERKAILERIEE 1011
|
....*
gi 1039770412 728 ERELK 732
Cdd:TIGR02169 1012 YEKKK 1016
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2-747 |
3.34e-16 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 84.73 E-value: 3.34e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 2 LLGEEAMMEQEMTRLHRRVSEVEAVLSQKEVELkasetqrslleQDLATyitECSSLKRSLEQARMEVSQE-DDKALQLL 80
Cdd:TIGR02169 228 LLKEKEALERQKEAIERQLASLEEELEKLTEEI-----------SELEK---RLEEIEQLLEELNKKIKDLgEEEQLRVK 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 81 HDIREQSRKLQEIkeqeyQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKLMKAKDQGKP 160
Cdd:TIGR02169 294 EKIGELEAEIASL-----ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELED 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 161 EVGEYSKLEKINAEQQLKIQELQEKLEKAVKastEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRhs 240
Cdd:TIGR02169 369 LRAELEEVDKEFAETRDELKDYREKLEKLKR---EINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEK-- 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 241 lENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQ---HYEEKIKVLDNQIKK 317
Cdd:TIGR02169 444 -EDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEErvrGGRAVEEVLKASIQG 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 318 -------------------DLADKESLENMMQRHEEEAHEKGKILSEQKAM------INAMDSKIRSLE--------QRI 364
Cdd:TIGR02169 523 vhgtvaqlgsvgeryataiEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGratflpLNKMRDERRDLSilsedgviGFA 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 365 VELSEANKLAANSSLFTQRNMKAQEEMISELRQQ-KFYLETQAGKLeaqnrkleeqLEKI-SHQDHSDKSRLLELETR-L 441
Cdd:TIGR02169 603 VDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMgKYRMVTLEGEL----------FEKSgAMTGGSRAPRGGILFSRsE 672
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 442 REVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDA 521
Cdd:TIGR02169 673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQE 752
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 522 LRNSCTVITDLEEQLNQLTEDnaelnnqnfylskqldeasgandeIVQLRSEVDHLRREITEREMQLTSQKqtMEALKTT 601
Cdd:TIGR02169 753 IENVKSELKELEARIEELEED------------------------LHKLEEALNDLEARLSHSRIPEIQAE--LSKLEEE 806
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 602 CTMLEEQVLDLEA-LNDELLEKErqweawrsvLGDEKSQfecrvRELQRMLDTEKQSRARADQritesrqvvelaVKEHK 680
Cdd:TIGR02169 807 VSRIEARLREIEQkLNRLTLEKE---------YLEKEIQ-----ELQEQRIDLKEQIKSIEKE------------IENLN 860
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770412 681 AEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQK---LETERE-LKQRLLEEQAKLQQQMD 747
Cdd:TIGR02169 861 GKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKieeLEAQIEkKRKRLSELKAKLEALEE 931
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
173-848 |
7.85e-16 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 83.58 E-value: 7.85e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 173 AEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEgiKKKLVEAEERRHSLENKVKRLETME 252
Cdd:TIGR02169 166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLK--EKREYEGYELLKEKEALERQKEAIE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 253 RRENRLKDDIQTKSEQIQQMADKILELEEKHRE-------------AQVSAQHLEVH-----LKQKEQHYEEKIKVLDNQ 314
Cdd:TIGR02169 244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEElnkkikdlgeeeqLRVKEKIGELEaeiasLERSIAEKERELEDAEER 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 315 IKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLaansslfTQRNMKAQEEMISE 394
Cdd:TIGR02169 324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE-------TRDELKDYREKLEK 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 395 LRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELK----------RQLTELQL 464
Cdd:TIGR02169 397 LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEqlaadlskyeQELYDLKE 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 465 SLQERESQLTALQAARAALESQLRQAKTELEETTAEAE------------------------------------------ 502
Cdd:TIGR02169 477 EYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEvlkasiqgvhgtvaqlgsvgeryataievaagnrlnnvvved 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 503 -----EEIQALTAHR--------------------------------------DEIQRKFDALRNSCTVITDLEEQLNQL 539
Cdd:TIGR02169 557 davakEAIELLKRRKagratflplnkmrderrdlsilsedgvigfavdlvefdPKYEPAFKYVFGDTLVVEDIEAARRLM 636
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 540 TE--------------------DNAELNNQNFYLSkQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALK 599
Cdd:TIGR02169 637 GKyrmvtlegelfeksgamtggSRAPRGGILFSRS-EPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 600 ttcTMLEEQVLDLEALNDElLEKERQweawrsvlgdEKSQFECRVRELQRMLDTEKQSRARADQRITEsrqvVELAVKEH 679
Cdd:TIGR02169 716 ---RKIGEIEKEIEQLEQE-EEKLKE----------RLEELEEDLSSLEQEIENVKSELKELEARIEE----LEEDLHKL 777
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 680 KAEILALQQALKEQKLkaESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIfrltqg 759
Cdd:TIGR02169 778 EEALNDLEARLSHSRI--PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQI------ 849
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 760 lQEALDRADLLKTERSDLEYQLENIQVlyshEKVKMEGTISQQTKLIDFLQAKMDQPAKKkkvplqYNELKLALEKEKAR 839
Cdd:TIGR02169 850 -KSIEKEIENLNGKKEELEEELEELEA----ALRDLESRLGDLKKERDELEAQLRELERK------IEELEAQIEKKRKR 918
|
....*....
gi 1039770412 840 CAELEEALQ 848
Cdd:TIGR02169 919 LSELKAKLE 927
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
204-796 |
2.41e-15 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 82.03 E-value: 2.41e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 204 RQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKH 283
Cdd:PRK03918 144 DESREKVVRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREEL 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 284 REAQVSAQHLEVHlkqkeqhyEEKIKVLDNQIKKDLADKESLENMMQRHEEeahekgkilseqkaMINAMDSKIRSLEQR 363
Cdd:PRK03918 224 EKLEKEVKELEEL--------KEEIEELEKELESLEGSKRKLEEKIRELEE--------------RIEELKKEIEELEEK 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 364 IVELSEANKLAansslftqRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKIShqdhSDKSRLLELETRLRE 443
Cdd:PRK03918 282 VKELKELKEKA--------EEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE----EKEERLEELKKKLKE 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 444 V-----SLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALEsqLRQAKTELEETTAEAEEEIQALTAHRDEIQRK 518
Cdd:PRK03918 350 LekrleELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEE--LEKAKEEIEEEISKITARIGELKKEIKELKKA 427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 519 FDALRNS------CTVITDLEEQLNQLTEDNAELNNqnfyLSKQLDEASganDEIVQLRSEVDHLRREItEREMQLTSQK 592
Cdd:PRK03918 428 IEELKKAkgkcpvCGRELTEEHRKELLEEYTAELKR----IEKELKEIE---EKERKLRKELRELEKVL-KKESELIKLK 499
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 593 QTMEALKTTCTMLEEQVL-DLEALNDE---LLEKERQWEAWRSVLGDE---KSQFECRVRELQRMLDTEKQSRARADQRI 665
Cdd:PRK03918 500 ELAEQLKELEEKLKKYNLeELEKKAEEyekLKEKLIKLKGEIKSLKKElekLEELKKKLAELEKKLDELEEELAELLKEL 579
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 666 TE----SRQVVELAVKEHKA---EILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEE 738
Cdd:PRK03918 580 EElgfeSVEELEERLKELEPfynEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEE 659
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770412 739 Q-AKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIqvlyshEKVKME 796
Cdd:PRK03918 660 EyEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER------EKAKKE 712
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
235-930 |
4.52e-15 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 81.32 E-value: 4.52e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 235 EERRHSLENKVKRL----ETMERRENRLKD---DIQTKSEQIQQMADKILELeeKHREAQvSAQHLEVHLkQKEQHYEEK 307
Cdd:pfam15921 81 EEYSHQVKDLQRRLnesnELHEKQKFYLRQsviDLQTKLQEMQMERDAMADI--RRRESQ-SQEDLRNQL-QNTVHELEA 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 308 IKVLDNQIKKDLADK-ESLENMMQRHEEEAHE-----------KGKILSEQKAM---------------INAMDSKIRSL 360
Cdd:pfam15921 157 AKCLKEDMLEDSNTQiEQLRKMMLSHEGVLQEirsilvdfeeaSGKKIYEHDSMstmhfrslgsaiskiLRELDTEISYL 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 361 EQRIVELSEA-NKLAANSS----LFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKS--- 432
Cdd:pfam15921 237 KGRIFPVEDQlEALKSESQnkieLLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSmym 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 433 -RLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAH 511
Cdd:pfam15921 317 rQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 512 RDEIQRKFDALRNSCTVITDLEEQLNQ-----------LTEDNAELNNQnfyLSKQLDEASGANDEI-------VQLRSE 573
Cdd:pfam15921 397 KEQNKRLWDRDTGNSITIDHLRRELDDrnmevqrlealLKAMKSECQGQ---MERQMAAIQGKNESLekvssltAQLEST 473
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 574 VDHLRREITEremqLTSQKQTMEALKTTctmleeqVLDLEAlndELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDT 653
Cdd:pfam15921 474 KEMLRKVVEE----LTAKKMTLESSERT-------VSDLTA---SLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNE 539
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 654 EKQSR-------------ARADQRITESRQVVEL-------------AVKEHKA----EILALQQALKEQKLKAESLSDK 703
Cdd:pfam15921 540 GDHLRnvqtecealklqmAEKDKVIEILRQQIENmtqlvgqhgrtagAMQVEKAqlekEINDRRLELQEFKILKDKKDAK 619
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 704 LNDLEKKHAMLEMNARSL----QQKLETERELKQrlleEQAKLQQQMDLQKNHIFRLTQGLqEALDR-----ADLLKTER 774
Cdd:pfam15921 620 IRELEARVSDLELEKVKLvnagSERLRAVKDIKQ----ERDQLLNEVKTSRNELNSLSEDY-EVLKRnfrnkSEEMETTT 694
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 775 SDLEYQLENIQ--------VLYSHE---------KVKMEGTISQQTKLIDFLQAKMD------QPAKKKKVPLQYNELKL 831
Cdd:pfam15921 695 NKLKMQLKSAQseleqtrnTLKSMEgsdghamkvAMGMQKQITAKRGQIDALQSKIQfleeamTNANKEKHFLKEEKNKL 774
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 832 ALE-----KEKARCAELEEAL--QKTRIELRSAREEAAHRKATDHPHPSTPATARQQiamSAIVRSPEHQPSAMSLLAPP 904
Cdd:pfam15921 775 SQElstvaTEKNKMAGELEVLrsQERRLKEKVANMEVALDKASLQFAECQDIIQRQE---QESVRLKLQHTLDVKELQGP 851
|
810 820
....*....|....*....|....*.
gi 1039770412 905 SSRRKESSTPEEFSRRLKERMHHNIP 930
Cdd:pfam15921 852 GYTSNSSMKPRLLQPASFTRTHSNVP 877
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
135-847 |
1.03e-14 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 80.01 E-value: 1.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 135 LAAEEFKrkanecQHKLMKAKDQGKPEvgEYSKLEKINAEQQLKIQELQEKLEKAVKastEATELLQNIRQAKERAEREL 214
Cdd:TIGR00618 181 LALMEFA------KKKSLHGKAELLTL--RSQLLTLCTPCMPDTYHERKQVLEKELK---HLREALQQTQQSHAYLTQKR 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 215 EKLHNREDSSEGIKKKLVEAEErrhsLENKVKRLETMERRENRlkddiQTKSEQIQQMADKILELEEKHREAQVSAQHLE 294
Cdd:TIGR00618 250 EAQEEQLKKQQLLKQLRARIEE----LRAQEAVLEETQERINR-----ARKAAPLAAHIKAVTQIEQQAQRIHTELQSKM 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 295 VHLKQKEQHYEEKIKVldnqiKKDLADKESLENMMQRHEEE---AHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEAN 371
Cdd:TIGR00618 321 RSRAKLLMKRAAHVKQ-----QSSIEEQRRLLQTLHSQEIHirdAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKL 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 372 KLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLRevSLEHEEQ 451
Cdd:TIGR00618 396 QSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQ--SLKEREQ 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 452 KLELKRQLTelqlslqERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITD 531
Cdd:TIGR00618 474 QLQTKEQIH-------LQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEED 546
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 532 LEEQLNQLTEDNAELNNQ------NFYLSKQLDEASGANDEIVQ------------LRSEVDHLRREITEREMQLTSQKQ 593
Cdd:TIGR00618 547 VYHQLTSERKQRASLKEQmqeiqqSFSILTQCDNRSKEDIPNLQnitvrlqdltekLSEAEDMLACEQHALLRKLQPEQD 626
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 594 TMEALKTTCTMLEEQVLDLEALNDELLE--KERQWEAWRSVLGDEKSQFECRVRELQRMldtekQSRARADQRITESRQV 671
Cdd:TIGR00618 627 LQDVRLHLQQCSQELALKLTALHALQLTltQERVREHALSIRVLPKELLASRQLALQKM-----QSEKEQLTYWKEMLAQ 701
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 672 VELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKN 751
Cdd:TIGR00618 702 CQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELS 781
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 752 HIFRLTQGLQEALD-RADLLKTERSDLEYQL---ENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKVPLQYN 827
Cdd:TIGR00618 782 HLAAEIQFFNRLREeDTHLLKTLEAEIGQEIpsdEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQL 861
|
730 740
....*....|....*....|
gi 1039770412 828 ElklALEKEKARCAELEEAL 847
Cdd:TIGR00618 862 A---QLTQEQAKIIQLSDKL 878
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2-492 |
1.07e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 79.98 E-value: 1.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 2 LLGEEAMMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLH 81
Cdd:COG1196 293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 82 DIREQSRKLQEIKEQEYQAQVEEMRLM--MNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKLMKAKdqgk 159
Cdd:COG1196 373 ELAEAEEELEELAEELLEALRAAAELAaqLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA---- 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 160 pevgeySKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRH 239
Cdd:COG1196 449 ------EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 240 S-------------------------LENKVKRLETMERRENRLKDDIQTKSEQIQqmADKILELEEKHREAQVSAQHLE 294
Cdd:COG1196 523 AgavavligveaayeaaleaalaaalQNIVVEDDEVAAAAIEYLKAAKAGRATFLP--LDKIRARAALAAALARGAIGAA 600
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 295 VHLKQKEQHYEEKIKVLDNQIKK----DLADKESLENMMQRHEEEAHEK---GKILSEQKAMI----NAMDSKIRSLEQR 363
Cdd:COG1196 601 VDLVASDLREADARYYVLGDTLLgrtlVAARLEAALRRAVTLAGRLREVtleGEGGSAGGSLTggsrRELLAALLEAEAE 680
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 364 IVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDkSRLLELETRLRE 443
Cdd:COG1196 681 LEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL-LEEEALEELPEP 759
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 1039770412 444 VSLEHEEQKLE-LKRQLTEL----QLSLQEresqLTALQAARAALESQ---LRQAKT 492
Cdd:COG1196 760 PDLEELERELErLEREIEALgpvnLLAIEE----YEELEERYDFLSEQredLEEARE 812
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
5-923 |
6.40e-14 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 77.47 E-value: 6.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 5 EEAMMEQEMTRLHRRVSEVEAVLSQKEVELKASETQrslleqdlatyitecsslkrsLEQAR-MEVSQEDdkalqLLHDI 83
Cdd:pfam15921 136 ESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQ---------------------IEQLRkMMLSHEG-----VLQEI 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 84 REQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEfkrkanecQHKLMKAKDQGKPEV- 162
Cdd:pfam15921 190 RSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVED--------QLEALKSESQNKIELl 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 163 --GEYSKLEKINAEQQLKIQELQeklEKAVKASTEATELLQNIRQAKERAeRELEKLHNREDSsegikkklveaeerrhS 240
Cdd:pfam15921 262 lqQHQDRIEQLISEHEVEITGLT---EKASSARSQANSIQSQLEIIQEQA-RNQNSMYMRQLS----------------D 321
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 241 LENKVKRLETMERRENRLKDdiqtkseqiqqmaDKILELEEKhreaQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLA 320
Cdd:pfam15921 322 LESTVSQLRSELREAKRMYE-------------DKIEELEKQ----LVLANSELTEARTERDQFSQESGNLDDQLQKLLA 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 321 DKESLENMMQRHEEeahEKGKILSEQKAMINAMDSKIRSLEQRIVELseanklaansslftQRNMKAQEEMISELRQQkf 400
Cdd:pfam15921 385 DLHKREKELSLEKE---QNKRLWDRDTGNSITIDHLRRELDDRNMEV--------------QRLEALLKAMKSECQGQ-- 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 401 yLETQAGKLEAQNrkleEQLEKIShqdhSDKSRLLELETRLREVSLEHEEQKLEL---KRQLTELQLSLQERESQLTALQ 477
Cdd:pfam15921 446 -MERQMAAIQGKN----ESLEKVS----SLTAQLESTKEMLRKVVEELTAKKMTLessERTVSDLTASLQEKERAIEATN 516
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 478 AARAALESQLrqakteleETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNfylskql 557
Cdd:pfam15921 517 AEITKLRSRV--------DLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQH------- 581
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 558 DEASGAndeivqLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEalndelLEKERQWEAwrsvlGDEk 637
Cdd:pfam15921 582 GRTAGA------MQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE------LEKVKLVNA-----GSE- 643
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 638 sqfecrvrelqrmldtekqsRARADQRITESRQVVELAVKEHKAEILALQQalkEQKLKAESLSDKLNDLEKKHAMLEMN 717
Cdd:pfam15921 644 --------------------RLRAVKDIKQERDQLLNEVKTSRNELNSLSE---DYEVLKRNFRNKSEEMETTTNKLKMQ 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 718 ARSLQQKLETERELKQRL-------LEEQAKLQQQMDLQKNHIFRLT---QGLQEALDRAD----LLKTERSDLEYQLEN 783
Cdd:pfam15921 701 LKSAQSELEQTRNTLKSMegsdghaMKVAMGMQKQITAKRGQIDALQskiQFLEEAMTNANkekhFLKEEKNKLSQELST 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 784 IqvlySHEKVKMEGTI----SQQTKLidflqakmdqpakKKKVPlqynELKLALEKEKARCAELEEALQktRIELRSARE 859
Cdd:pfam15921 781 V----ATEKNKMAGELevlrSQERRL-------------KEKVA----NMEVALDKASLQFAECQDIIQ--RQEQESVRL 837
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770412 860 EAAHR---KATDHP-HPSTPATARQQIAMSAIVRSPEHQPSAMSLLAPPSSR-RKESSTPEEFSRRLKE 923
Cdd:pfam15921 838 KLQHTldvKELQGPgYTSNSSMKPRLLQPASFTRTHSNVPSSQSTASFLSHHsRKTNALKEDPTRDLKQ 906
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
564-866 |
8.16e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 76.90 E-value: 8.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 564 NDEIVQLRSEVDHLRR--EITEREMQLTSQKQTMEAlkttctmlEEQVLDLEALNDELLEKERQWEAwrsvLGDEKSQFE 641
Cdd:COG1196 192 EDILGELERQLEPLERqaEKAERYRELKEELKELEA--------ELLLLKLRELEAELEELEAELEE----LEAELEELE 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 642 CRVRELQRMLDTEKQSRARADQRITESRQvvelAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSL 721
Cdd:COG1196 260 AELAELEAELEELRLELEELELELEEAQA----EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 722 QQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQ 801
Cdd:COG1196 336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER 415
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039770412 802 QTKLIDFLQAKMDQPAKKKKVPLqynELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKA 866
Cdd:COG1196 416 LERLEEELEELEEALAELEEEEE---EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
57-866 |
1.71e-13 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 76.14 E-value: 1.71e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 57 SLKRSLEQARMEVSQEDDKALQLLHDIREQSRkLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESE--LRESR 134
Cdd:COG3096 289 ELRRELFGARRQLAEEQYRLVEMARELEELSA-RESDLEQDYQAASDHLNLVQTALRQQEKIERYQEDLEELTerLEEQE 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 135 LAAEEFKRKANECQHKLMKAKDqgkpevgEYSKLEKINAEQQLKIQELQeklekavkasTEATELlQNIRQAKERAEREL 214
Cdd:COG3096 368 EVVEEAAEQLAEAEARLEAAEE-------EVDSLKSQLADYQQALDVQQ----------TRAIQY-QQAVQALEKARALC 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 215 EK----LHNREDSSEGIKKKLVEAEERRHSLENKVkrletmerrenRLKDDIQTKSEQIQQMADKIL------------- 277
Cdd:COG3096 430 GLpdltPENAEDYLAAFRAKEQQATEEVLELEQKL-----------SVADAARRQFEKAYELVCKIAgeversqawqtar 498
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 278 ELEEKHREAQVSAQ---HLEVHLKQKEQHY------EEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKA 348
Cdd:COG3096 499 ELLRRYRSQQALAQrlqQLRAQLAELEQRLrqqqnaERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVE 578
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 349 MINAMDSKIRSLEQRIVELS--EANKLAANSSLFTQRNMKAQE----EMISELRQQKFYLETQA----GKLEAQNRKLEE 418
Cdd:COG3096 579 QRSELRQQLEQLRARIKELAarAPAWLAAQDALERLREQSGEAladsQEVTAAMQQLLEREREAtverDELAARKQALES 658
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 419 QLEKISHQDHSDKSRLLELETRLREV--SLEHEEQKLE-----------------------LKRQLTELQ-----LSLQE 468
Cdd:COG3096 659 QIERLSQPGGAEDPRLLALAERLGGVllSEIYDDVTLEdapyfsalygparhaivvpdlsaVKEQLAGLEdcpedLYLIE 738
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 469 R------ESQLTALQAARAAL----ESQLRQAKTELEET--TAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQL 536
Cdd:COG3096 739 GdpdsfdDSVFDAEELEDAVVvklsDRQWRYSRFPEVPLfgRAAREKRLEELRAERDELAEQYAKASFDVQKLQRLHQAF 818
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 537 NQLtednaelnnqnfyLSKQLDEASGANDE--IVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTML--------- 605
Cdd:COG3096 819 SQF-------------VGGHLAVAFAPDPEaeLAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLnkllpqanl 885
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 606 ------EEQVLDLEALNDELLEKER----------QWEAWRSVLGDEKSQFEcrvrELQRMLDTEKQSRARADQRI---T 666
Cdd:COG3096 886 ladetlADRLEELREELDAAQEAQAfiqqhgkalaQLEPLVAVLQSDPEQFE----QLQADYLQAKEQQRRLKQQIfalS 961
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 667 ESRQVVELAVKEHKAEIL----ALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKL 742
Cdd:COG3096 962 EVVQRRPHFSYEDAVGLLgensDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQE 1041
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 743 QQQMDLQKNHifrltqglqEALDRAdllKTERSDLEYQLeniqvlyshekVKMEGTISQQTKLIDFLQAKMDQPAKK-KK 821
Cdd:COG3096 1042 LEELGVQADA---------EAEERA---RIRRDELHEEL-----------SQNRSRRSQLEKQLTRCEAEMDSLQKRlRK 1098
|
890 900 910 920
....*....|....*....|....*....|....*....|....*
gi 1039770412 822 VPLQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKA 866
Cdd:COG3096 1099 AERDYKQEREQVVQAKAGWCAVLRLARDNDVERRLHRRELAYLSA 1143
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
5-485 |
2.43e-13 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 75.49 E-value: 2.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 5 EEAMMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQdLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIR 84
Cdd:PRK03918 246 ELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE-LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEIN 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 85 EQSRKLQEIKEQEyqAQVEEMRLMMNQLEEDLvsarrrsdlyeSELRESRLAAEEFKRKANECQhKLMKAKDQGKPE--V 162
Cdd:PRK03918 325 GIEERIKELEEKE--ERLEELKKKLKELEKRL-----------EELEERHELYEEAKAKKEELE-RLKKRLTGLTPEklE 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 163 GEYSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAE---RELEKLHNREDSSE------GIKKKLVE 233
Cdd:PRK03918 391 KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPvcgRELTEEHRKELLEEytaelkRIEKELKE 470
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 234 AEERRHSLENKVKRLETMERRENRLKddiqtkseQIQQMADKILELEEKHREaqVSAQHLEVHLKQKEQHYEEKIKVLDN 313
Cdd:PRK03918 471 IEEKERKLRKELRELEKVLKKESELI--------KLKELAEQLKELEEKLKK--YNLEELEKKAEEYEKLKEKLIKLKGE 540
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 314 Q--IKKDLADKESLENMMQRHEEEAHEKGKILSE-QKAMINAMDSKIRSLEQRIVELSEANK---LAANSSLFTQRNMKA 387
Cdd:PRK03918 541 IksLKKELEKLEELKKKLAELEKKLDELEEELAElLKELEELGFESVEELEERLKELEPFYNeylELKDAEKELEREEKE 620
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 388 QEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKS-RLLELETRLREVslehEEQKLELKRQLTELQLSL 466
Cdd:PRK03918 621 LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELReEYLELSRELAGL----RAELEELEKRREEIKKTL 696
|
490
....*....|....*....
gi 1039770412 467 QERESQLTALQAARAALES 485
Cdd:PRK03918 697 EKLKEELEEREKAKKELEK 715
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
10-573 |
3.03e-13 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 75.08 E-value: 3.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 10 EQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLatyiTECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRK 89
Cdd:PRK02224 198 EKEEKDLHERLNGLESELAELDEEIERYEEQREQARETR----DEADEVLEEHEERREELETLEAEIEDLRETIAETERE 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 90 LQEIKEQeyqaqVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKLMkakdqgkpevgeyskle 169
Cdd:PRK02224 274 REELAEE-----VRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLE----------------- 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 170 kinaEQQLKIQElqeklekavkASTEATELLQNIRQAKERAERELEKlhnREDSSEGIKKKLVEAEERRHSLENKVKRLE 249
Cdd:PRK02224 332 ----ECRVAAQA----------HNEEAESLREDADDLEERAEELREE---AAELESELEEAREAVEDRREEIEELEEEIE 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 250 TMERRENRLkddiqtkSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLD-------NQIKKDLADK 322
Cdd:PRK02224 395 ELRERFGDA-------PVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEagkcpecGQPVEGSPHV 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 323 ESLENMMQRHEEEAHEkgkiLSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQR------NMKAQEEMISELR 396
Cdd:PRK02224 468 ETIEEDRERVEELEAE----LEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELiaerreTIEEKRERAEELR 543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 397 QQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVS--------LEHEEQKLE-LKRQLTELQLSLQ 467
Cdd:PRK02224 544 ERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLErirtllaaIADAEDEIErLREKREALAELND 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 468 ERESQLTALQAARAALES--------QLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCtvitdleEQLNQL 539
Cdd:PRK02224 624 ERRERLAEKRERKRELEAefdearieEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL-------EELEEL 696
|
570 580 590
....*....|....*....|....*....|....
gi 1039770412 540 TEDNAELNNQNFYLSKQLDEASGANDEIVQLRSE 573
Cdd:PRK02224 697 RERREALENRVEALEALYDEAEELESMYGDLRAE 730
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
155-663 |
4.31e-13 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 74.03 E-value: 4.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 155 KDQGKPEVGEYSKLEKinAEQQLK-IQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKkklvE 233
Cdd:COG4717 60 KPQGRKPELNLKELKE--LEEELKeAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQ----E 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 234 AEERRHSLENKVKRLETMERRENRLKD---DIQTKSEQIQQMADKILELEE-----KHREAQVSAQHLEvHLKQKEQHYE 305
Cdd:COG4717 134 LEALEAELAELPERLEELEERLEELREleeELEELEAELAELQEELEELLEqlslaTEEELQDLAEELE-ELQQRLAELE 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 306 EKIKVLDNQIKKDLADKESLENMMQRHEEEAH-EKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKL-AANSSLFTQR 383
Cdd:COG4717 213 EELEEAQEELEELEEELEQLENELEAAALEERlKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLvLGLLALLFLL 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 384 NMKAQEEMISELRQqkfyLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREV-----SLEHEEQKLELKRQ 458
Cdd:COG4717 293 LAREKASLGKEAEE----LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELqellrEAEELEEELQLEEL 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 459 LTELQLSLQ--------------ERESQLTALQAARAALESQLRQAKTELEEttaeaeeeiQALTAHRDEIQRKFDALRN 524
Cdd:COG4717 369 EQEIAALLAeagvedeeelraalEQAEEYQELKEELEELEEQLEELLGELEE---------LLEALDEEELEEELEELEE 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 525 SctvITDLEEQLNQLTEDNAELNNQNFYLSKQldeasganDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTM 604
Cdd:COG4717 440 E---LEELEEELEELREELAELEAELEQLEED--------GELAELLQELEELKAELRELAEEWAALKLALELLEEAREE 508
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039770412 605 LEEQVLdlealnDELLEKERQW------EAWRSVLGDEKSQFECRvRELQRMLDTEKQSRARADQ 663
Cdd:COG4717 509 YREERL------PPVLERASEYfsrltdGRYRLIRIDEDLSLKVD-TEDGRTRPVEELSRGTREQ 566
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
33-621 |
4.48e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 74.29 E-value: 4.48e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 33 ELKASETQRSLLEqdlatyiTECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQeyqaqVEEMRLMMNQL 112
Cdd:TIGR04523 111 EIKNDKEQKNKLE-------VELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQ-----KEELENELNLL 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 113 EEDLVSARRRSDLYESELRESRL---AAEEFKRKANECQHKLMKAKDQgkpevgeYSKLEKINAEQQLKIQELQEKLEKA 189
Cdd:TIGR04523 179 EKEKLNIQKNIDKIKNKLLKLELllsNLKKKIQKNKSLESQISELKKQ-------NNQLKDNIEKKQQEINEKTTEISNT 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 190 VkasteatellQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSLENKVKRLETMERRE--NRLKDDIQTKSE 267
Cdd:TIGR04523 252 Q----------TQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDwnKELKSELKNQEK 321
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 268 QIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLD---NQIKKDLADKESLENMMQRHEEEAHEKGKILS 344
Cdd:TIGR04523 322 KLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEekqNEIEKLKKENQSYKQEIKNLESQINDLESKIQ 401
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 345 EQKAMINAMDSKIRSLEQrivelsEANKLAANSSLFTQRNMKAQEEmISELRQQKFYLETQAGKLEAQNRKLEEQLEKIS 424
Cdd:TIGR04523 402 NQEKLNQQKDEQIKKLQQ------EKELLEKEIERLKETIIKNNSE-IKDLTNQDSVKELIIKNLDNTRESLETQLKVLS 474
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 425 HQDHSDKSRLLELETRLREVSLEHE---EQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKteleettaea 501
Cdd:TIGR04523 475 RSINKIKQNLEQKQKELKSKEKELKklnEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLE---------- 544
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 502 eeeiqaltahrDEIQRKFDALRNSC--TVITDLEEQLNQLTEDNAELNNQNFYLSKQLDeasgandeivQLRSEVDHLRR 579
Cdd:TIGR04523 545 -----------DELNKDDFELKKENleKEIDEKNKEIEELKQTQKSLKKKQEEKQELID----------QKEKEKKDLIK 603
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 1039770412 580 EITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLE 621
Cdd:TIGR04523 604 EIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQ 645
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
81-785 |
5.26e-13 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 74.61 E-value: 5.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 81 HDIREQSRKLQEIK------EQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELR--ESRLAAEEFKRKANECQHKLM 152
Cdd:PRK04863 307 YRLVEMARELAELNeaesdlEQDYQAASDHLNLVQTALRQQEKIERYQADLEELEERleEQNEVVEEADEQQEENEARAE 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 153 KAKDqgkpevgEYSKLEKINAEQQLKIQELQEK---LEKAVKASTEATELLQNIRQAKERAERELEKLHNREDssegikk 229
Cdd:PRK04863 387 AAEE-------EVDELKSQLADYQQALDVQQTRaiqYQQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQ------- 452
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 230 klvEAEERRHSLENKVkrletmerrenRLKDDIQTKSEQIQQMADKIL-------------ELEEKHREAQ---VSAQHL 293
Cdd:PRK04863 453 ---EATEELLSLEQKL-----------SVAQAAHSQFEQAYQLVRKIAgevsrseawdvarELLRRLREQRhlaEQLQQL 518
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 294 EVHLKQKEQHYEEKIKV--LDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIR----SLEQRIVEL 367
Cdd:PRK04863 519 RMRLSELEQRLRQQQRAerLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRqqleQLQARIQRL 598
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 368 S--EANKLAANSSLFTQRNMKAQE----EMISELRQQKFYLETQA----GKLEAQNRKLEEQLEKISHQDHSDKSRLLEL 437
Cdd:PRK04863 599 AarAPAWLAAQDALARLREQSGEEfedsQDVTEYMQQLLERERELtverDELAARKQALDEEIERLSQPGGSEDPRLNAL 678
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 438 ETRLREVSLE--HEEQKLE-----------------------LKRQLTELQ-----LSLQE------RESQLTALQAARA 481
Cdd:PRK04863 679 AERFGGVLLSeiYDDVSLEdapyfsalygparhaivvpdlsdAAEQLAGLEdcpedLYLIEgdpdsfDDSVFSVEELEKA 758
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 482 AL----ESQLRQAKTELEET--TAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTednaelnNQNFYLSK 555
Cdd:PRK04863 759 VVvkiaDRQWRYSRFPEVPLfgRAAREKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFI-------GSHLAVAF 831
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 556 QLDEasgaNDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEE-----QVLDLEALNDELLEKERQWEAWR 630
Cdd:PRK04863 832 EADP----EAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRllprlNLLADETLADRVEEIREQLDEAE 907
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 631 --------------------SVLGDEKSQFEcrvrELQRMLDTEKQSRARADQRI---TESRQVVELAVKEHKAEILA-- 685
Cdd:PRK04863 908 eakrfvqqhgnalaqlepivSVLQSDPEQFE----QLKQDYQQAQQTQRDAKQQAfalTEVVQRRAHFSYEDAAEMLAkn 983
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 686 --LQQALKEQKLKAESLSDKLNDLEKKHA--MLEMNAR------SLQQKLETERELKQRL----------LEEQAKLQQQ 745
Cdd:PRK04863 984 sdLNEKLRQRLEQAEQERTRAREQLRQAQaqLAQYNQVlaslksSYDAKRQMLQELKQELqdlgvpadsgAEERARARRD 1063
|
810 820 830 840
....*....|....*....|....*....|....*....|
gi 1039770412 746 mdlqknhifRLTQGLQEALDRADLLKTERSDLEYQLENIQ 785
Cdd:PRK04863 1064 ---------ELHARLSANRSRRNQLEKQLTFCEAEMDNLT 1094
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
44-600 |
7.20e-13 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 73.78 E-value: 7.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 44 LEQDLATYITECSSLKRSLEQarmevsqeDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEdlvsarrrS 123
Cdd:PRK01156 188 LEEKLKSSNLELENIKKQIAD--------DEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDM--------K 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 124 DLYESELR--ESRLAAEEFKR-KANECQHKLMKAKDQ----GKPEVGEYSKLEKINAEQQLKIQELQEKLEKAVKASTEA 196
Cdd:PRK01156 252 NRYESEIKtaESDLSMELEKNnYYKELEERHMKIINDpvykNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKL 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 197 TELlQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEErrhSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKI 276
Cdd:PRK01156 332 SVL-QKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLK---SIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAI 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 277 L-ELEEKHREAQ------VSAQHLEVHLKQKEQHYEEKIKVLDNQIK-----KDLADKESlENMMQRHEEEAHEKGKILS 344
Cdd:PRK01156 408 KkELNEINVKLQdisskvSSLNQRIRALRENLDELSRNMEMLNGQSVcpvcgTTLGEEKS-NHIINHYNEKKSRLEEKIR 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 345 EQKAMINAMDSKIRSLEQRI--VELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEK 422
Cdd:PRK01156 487 EIEIEVKDIDEKIVDLKKRKeyLESEEINKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSK 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 423 ISHQDHSDKSR-LLELETrlrevsleHEEQKLELKRQLTELQLSLQERESQLTALQAAraaLESQLRQAKTELEETTAEA 501
Cdd:PRK01156 567 RTSWLNALAVIsLIDIET--------NRSRSNEIKKQLNDLESRLQEIEIGFPDDKSY---IDKSIREIENEANNLNNKY 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 502 EEeIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEasgANDEIVQLRSEVDHLRREI 581
Cdd:PRK01156 636 NE-IQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDD---AKANRARLESTIEILRTRI 711
|
570
....*....|....*....
gi 1039770412 582 TEREMQLTSQKQTMEALKT 600
Cdd:PRK01156 712 NELSDRINDINETLESMKK 730
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
174-797 |
9.48e-13 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 73.67 E-value: 9.48e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 174 EQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSsegikkkLVEAEERRHSLENKVKRLET--- 250
Cdd:pfam01576 6 EMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETEL-------CAEAEEMRARLAARKQELEEilh 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 251 -MERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLE---VHLKQKEQHYEEKIKVLDNQIKKDLADKESLE 326
Cdd:pfam01576 79 eLESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQlekVTTEAKIKKLEEDILLLEDQNSKLSKERKLLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 327 ---NMMQRHEEEAHEKGKILSEQKAMINAMdskirsleqrIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLE 403
Cdd:pfam01576 159 eriSEFTSNLAEEEEKAKSLSKLKNKHEAM----------ISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQ 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 404 TQAGKLEAQNRKLEEQLEkishqdhsdksrllELETRLREVSLeheeQKLELKRQLTELQLSLQERESQLTALQAARAAL 483
Cdd:pfam01576 229 AQIAELRAQLAKKEEELQ--------------AALARLEEETA----QKNNALKKIRELEAQISELQEDLESERAARNKA 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 484 ESQLRqakteleettaeaeeeiqaltahrdeiqrkfdalrnsctvitDLEEQLNQLTEDnaelnnqnfyLSKQLDEASGA 563
Cdd:pfam01576 291 EKQRR------------------------------------------DLGEELEALKTE----------LEDTLDTTAAQ 318
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 564 NDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCtmleeqvldLEALNDELLEKER---QWEAWRSVLGDEKSQF 640
Cdd:pfam01576 319 QELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQA---------LEELTEQLEQAKRnkaNLEKAKQALESENAEL 389
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 641 ECRVRELQRMLDTEKQSRARADQritesrQVVELAVKEHKAEILALQQALKEQKLKAE--SLSDKLNDLEKKHAMLEMNA 718
Cdd:pfam01576 390 QAELRTLQQAKQDSEHKRKKLEG------QLQELQARLSESERQRAELAEKLSKLQSEleSVSSLLNEAEGKNIKLSKDV 463
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 719 RSLQQKLETERELKQRllEEQAKLQ-----QQMDLQKNhifrltqGLQEALDRADllkTERSDLEYQLENIQVLYSHEKV 793
Cdd:pfam01576 464 SSLESQLQDTQELLQE--ETRQKLNlstrlRQLEDERN-------SLQEQLEEEE---EAKRNVERQLSTLQAQLSDMKK 531
|
....
gi 1039770412 794 KMEG 797
Cdd:pfam01576 532 KLEE 535
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
132-743 |
1.43e-12 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 72.77 E-value: 1.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 132 ESRLAAEEFKRKANECQHKLmKAKDQGKPEVGEYSKL---EKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKE 208
Cdd:PRK02224 173 DARLGVERVLSDQRGSLDQL-KAQIEEKEEKDLHERLnglESELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 209 RAER---ELEKLhnREDSSEGIKKKLVEAEERRhslENKVKRLETMERRENRLKD------DIQTKSEQIQQMADKILEL 279
Cdd:PRK02224 252 ELETleaEIEDL--RETIAETEREREELAEEVR---DLRERLEELEEERDDLLAEaglddaDAEAVEARREELEDRDEEL 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 280 EEKHREAQVSAQHlevHLKQKEQhYEEKIKVLDNQIKKDLADKESLENMMQRHEEEahekgkiLSEQKAMINAMDSKIRS 359
Cdd:PRK02224 327 RDRLEECRVAAQA---HNEEAES-LREDADDLEERAEELREEAAELESELEEAREA-------VEDRREEIEELEEEIEE 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 360 LEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQkfyLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELEt 439
Cdd:PRK02224 396 LRERFGDAPVDLGNAEDFLEELREERDELREREAELEAT---LRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIE- 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 440 rlrevslEHEEQKLELKRQLTELQLSLQERESQLTALQAARAAlESQLRQAKTELEETTaeaeeeiQALTAHRDEIQRKf 519
Cdd:PRK02224 472 -------EDRERVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEERREDLE-------ELIAERRETIEEK- 535
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 520 dalrnsctvitdlEEQLNQLTEDNAELNnqnfylskqlDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALK 599
Cdd:PRK02224 536 -------------RERAEELRERAAELE----------AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE 592
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 600 TTCTMLEEqVLDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQvvelavkeh 679
Cdd:PRK02224 593 RIRTLLAA-IADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYL--------- 662
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770412 680 kaeilalqqalkeqklkaESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQ 743
Cdd:PRK02224 663 ------------------EQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVE 708
|
|
| C1_MgcRacGAP |
cd20821 |
protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and ... |
929-983 |
2.17e-12 |
|
protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins; MgcRacGAP, also called Rac GTPase-activating protein 1 (RACGAP1) or protein CYK4, plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is critical for the structure of the central spindle by promoting microtuble bundling; and ii) after phosphorylation by aurora B, MgcRacGAP becomes an effective regulator of RhoA and plays an important role in the assembly of the contractile ring and the initiation of cytokinesis. MgcRacGAP-like proteins contain an N-terminal C1 domain, and a C-terminal RhoGAP domain. This model corresponds to the C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410371 Cd Length: 55 Bit Score: 63.19 E-value: 2.17e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1039770412 929 IPHRFNVGLNMRATKCAVCLDTVHFGRQASKCLECQVMCHPKCSTCLPATCGLPA 983
Cdd:cd20821 1 RPHRFVSKTVIKPETCVVCGKRIKFGKKALKCKDCRVVCHPDCKDKLPLPCVPTS 55
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
557-866 |
3.12e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.89 E-value: 3.12e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 557 LDEASGandeIVQLRSevdhlRREITEREMQLTSQkqtmealkttctmleeqvlDLEALNDELLEKERQWEAwrsvLGDE 636
Cdd:COG1196 161 IEEAAG----ISKYKE-----RKEEAERKLEATEE-------------------NLERLEDILGELERQLEP----LERQ 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 637 KSQFEcRVRELQRMLDT-EKQSRARADQRITESRQVVELAVKEHKAEILALQQ-------ALKEQKLKAESLSDKLNDLE 708
Cdd:COG1196 209 AEKAE-RYRELKEELKElEAELLLLKLRELEAELEELEAELEELEAELEELEAelaeleaELEELRLELEELELELEEAQ 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 709 KKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLY 788
Cdd:COG1196 288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770412 789 SHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKVPLQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKA 866
Cdd:COG1196 368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
13-760 |
4.34e-12 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 71.54 E-value: 4.34e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 13 MTRLHRRVSEVEAVLSQKEVELkasETQrsLLEQDLATYITECSSLKRSLEQARMEVSQE---DDKALQLLHDIREQSRK 89
Cdd:TIGR00618 184 MEFAKKKSLHGKAELLTLRSQL---LTL--CTPCMPDTYHERKQVLEKELKHLREALQQTqqsHAYLTQKREAQEEQLKK 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 90 LQEIKEQeyQAQVEEMRLMMNQLEEdLVSARRRSDLYESELRESRlAAEEFKRKANECQHKLMKAKDQGKPEVGEYSKLE 169
Cdd:TIGR00618 259 QQLLKQL--RARIEELRAQEAVLEE-TQERINRARKAAPLAAHIK-AVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHV 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 170 KINAEQQLKIQELQEkLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSLENKVKRLE 249
Cdd:TIGR00618 335 KQQSSIEEQRRLLQT-LHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATID 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 250 TMERRENRLKDDIQTKSEQiQQMADKILELEEKHREAQVSAQHLE-VHLKQKEQHYEEKIKVLDNqikkdladkesLENM 328
Cdd:TIGR00618 414 TRTSAFRDLQGQLAHAKKQ-QELQQRYAELCAAAITCTAQCEKLEkIHLQESAQSLKEREQQLQT-----------KEQI 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 329 MQRHEEEAHEKGKILSEQKaminamdSKIRSLEQRIVELSEANKLAANSSLFTQRnmkaqeemISELRQQKFYLETQAGK 408
Cdd:TIGR00618 482 HLQETRKKAVVLARLLELQ-------EEPCPLCGSCIHPNPARQDIDNPGPLTRR--------MQRGEQTYAQLETSEED 546
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 409 LEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLR 488
Cdd:TIGR00618 547 VYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQD 626
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 489 QAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDN-AELNNQNFYLSKQLDEASGANDEI 567
Cdd:TIGR00618 627 LQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLAlQKMQSEKEQLTYWKEMLAQCQTLL 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 568 VQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTML--EEQVLDLEALNDELLEKERQWEAWRSVL--GDEKSQFECR 643
Cdd:TIGR00618 707 RELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSlkELMHQARTVLKARTEAHFNNNEEVTAALqtGAELSHLAAE 786
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 644 VRELQRMLDTEKQSRARADQRITESRQVVELAVKehkAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQ 723
Cdd:TIGR00618 787 IQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILN---LQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQ 863
|
730 740 750
....*....|....*....|....*....|....*..
gi 1039770412 724 KLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGL 760
Cdd:TIGR00618 864 LTQEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHEI 900
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
334-864 |
5.98e-12 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 71.10 E-value: 5.98e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 334 EEAHEKGKILSEQKAM---INAMDSKIRSLEQRIVELSEAnkLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLE 410
Cdd:COG4913 238 ERAHEALEDAREQIELlepIRELAERYAAARERLAELEYL--RAALRLWFAQRRLELLEAELEELRAELARLEAELERLE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 411 AQNRKLEEQLEKISHQ-DHSDKSRLLELETRLREVSLEHEEQK---LELKRQLTELQLSLQERESQLTALQAARAALESQ 486
Cdd:COG4913 316 ARLDALREELDELEAQiRGNGGDRLEQLEREIERLERELEERErrrARLEALLAALGLPLPASAEEFAALRAEAAALLEA 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 487 LRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVI--------TDLEEQLN-------------QLTEDNAE 545
Cdd:COG4913 396 LEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIparllalrDALAEALGldeaelpfvgeliEVRPEEER 475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 546 --------LNNQNFYL---SKQLDEASGANDEIvqlrsevdHLRREI-TEREMQLTSQKQTMEALKTTctmleeqvldle 613
Cdd:COG4913 476 wrgaiervLGGFALTLlvpPEHYAAALRWVNRL--------HLRGRLvYERVRTGLPDPERPRLDPDS------------ 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 614 aLNDELLEKERQWEAW-RSVLGDEKSqFEC--RVRELQR---------MLDTEKQSRARADQRITESRQV----VELAVK 677
Cdd:COG4913 536 -LAGKLDFKPHPFRAWlEAELGRRFD-YVCvdSPEELRRhpraitragQVKGNGTRHEKDDRRRIRSRYVlgfdNRAKLA 613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 678 EHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLemnaRSLQQKLETERELKQrLLEEQAKLQQQMDlqknhifRLT 757
Cdd:COG4913 614 ALEAELAELEEELAEAEERLEALEAELDALQERREAL----QRLAEYSWDEIDVAS-AEREIAELEAELE-------RLD 681
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 758 QG---LQEALDRADLLKTERSDLEYQLENIQvlysHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKVPLQYN-ELKLAL 833
Cdd:COG4913 682 ASsddLAALEEQLEELEAELEELEEELDELK----GEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALlEERFAA 757
|
570 580 590
....*....|....*....|....*....|.
gi 1039770412 834 EKEKARCAELEEALQKTRIELRSAREEAAHR 864
Cdd:COG4913 758 ALGDAVERELRENLEERIDALRARLNRAEEE 788
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
127-752 |
1.14e-11 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 69.75 E-value: 1.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 127 ESELRESRLAAEEfKRKANECQHKLMKAKDQGKpevgeysklEKINAEQQLKIQElQEKLEKAVKASTEATELLQNI--R 204
Cdd:pfam05483 98 EAELKQKENKLQE-NRKIIEAQRKAIQELQFEN---------EKVSLKLEEEIQE-NKDLIKENNATRHLCNLLKETcaR 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 205 QAKERAERELEKLHNRE---DSSEGIKKKLVEAEERRHSLEN-------KVKR-LETMERRENRLKDDIQTKSEQIQQMA 273
Cdd:pfam05483 167 SAEKTKKYEYEREETRQvymDLNNNIEKMILAFEELRVQAENarlemhfKLKEdHEKIQHLEEEYKKEINDKEKQVSLLL 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 274 DKILELEEKHREAQVsaqhLEVHLKQKEQHYEEKIKVLDNQIKKDLADKESLENMMqrhEEEAHEKGKILSEQKAMINAM 353
Cdd:pfam05483 247 IQITEKENKMKDLTF----LLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKEL---EDIKMSLQRSMSTQKALEEDL 319
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 354 DSKIRSL----EQRIVELSEANKLAANSSLFT---QRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQ 426
Cdd:pfam05483 320 QIATKTIcqltEEKEAQMEELNKAKAAHSFVVtefEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKF 399
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 427 DHSDKSRLLELETRLREVSLEHEEQKL------ELKRQLTELQLSLQERES-------QLTALQAARAALESQLRQAKTE 493
Cdd:pfam05483 400 KNNKEVELEELKKILAEDEKLLDEKKQfekiaeELKGKEQELIFLLQAREKeihdleiQLTAIKTSEEHYLKEVEDLKTE 479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 494 LEETTAEAEEeiqaLTAHRDEIQRKFDALRNSCtviTDLEEQLNQLTEDnaeLNNQNFYLSKQLDEASGANDEIVQLRSE 573
Cdd:pfam05483 480 LEKEKLKNIE----LTAHCDKLLLENKELTQEA---SDMTLELKKHQED---IINCKKQEERMLKQIENLEEKEMNLRDE 549
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 574 VDHLRREIteremqltsqKQTMEALKTTCTMLEEQVLDLEAlndELLEKERQWEAWRSVLGDEKSQFECRVRELQRMldt 653
Cdd:pfam05483 550 LESVREEF----------IQKGDEVKCKLDKSEENARSIEY---EVLKKEKQMKILENKCNNLKKQIENKNKNIEEL--- 613
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 654 EKQSRARADQRITESRQvveLAVKEHKAEILALQQALKEQKLKaESLSDKLNDLEKKhamlemnaRSLQQKLETERELKQ 733
Cdd:pfam05483 614 HQENKALKKKGSAENKQ---LNAYEIKVNKLELELASAKQKFE-EIIDNYQKEIEDK--------KISEEKLLEEVEKAK 681
|
650
....*....|....*....
gi 1039770412 734 RLLEEQAKLQQQMDLQKNH 752
Cdd:pfam05483 682 AIADEAVKLQKEIDKRCQH 700
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
9-424 |
2.26e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 68.89 E-value: 2.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 9 MEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSR 88
Cdd:TIGR04523 216 LESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKS 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 89 KLQEIKEQEYQAqveemrlMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKLM------KAKDQGKPEv 162
Cdd:TIGR04523 296 EISDLNNQKEQD-------WNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTnsesenSEKQRELEE- 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 163 gEYSKLEKINAEQQLKIQELQeKLEkavkasTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSLE 242
Cdd:TIGR04523 368 -KQNEIEKLKKENQSYKQEIK-NLE------SQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNN 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 243 NKVKRLETMERRENRLKDDIQTKSEQIQQmadKILELEEKHREAQVSAQHLEVHLKQKEQHYE---EKIKVLDNQIKKDL 319
Cdd:TIGR04523 440 SEIKDLTNQDSVKELIIKNLDNTRESLET---QLKVLSRSINKIKQNLEQKQKELKSKEKELKklnEEKKELEEKVKDLT 516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 320 ADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDS---------KIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEE 390
Cdd:TIGR04523 517 KKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFelkkenlekEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEK 596
|
410 420 430
....*....|....*....|....*....|....
gi 1039770412 391 MISELRQQKFYLETQAGKLEAQNRKLEEQLEKIS 424
Cdd:TIGR04523 597 EKKDLIKEIEEKEKKISSLEKELEKAKKENEKLS 630
|
|
| C1_ScPKC1-like_rpt2 |
cd20823 |
second protein kinase C conserved region 1 (C1 domain) found in Saccharomyces cerevisiae ... |
927-984 |
7.31e-11 |
|
second protein kinase C conserved region 1 (C1 domain) found in Saccharomyces cerevisiae protein kinase C-like 1 (ScPKC1) and similar proteins; ScPKC1 is required for cell growth and for the G2 to M transition of the cell division cycle. It mediates a protein kinase cascade, activating BCK1 which itself activates MKK1/MKK2. The family also includes Schizosaccharomyces pombe PKC1 and PKC2, which are involved in the control of cell shape and act as targets of the inhibitor staurosporine. Members of this family contain two copies of C1 domain. This model corresponds to the second one. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410373 Cd Length: 59 Bit Score: 58.86 E-value: 7.31e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770412 927 HNIPHRFNVGLNMRATKCAVCLDTVHFGR-QASKCLECQVMCHPKCSTCLPATCGLPAE 984
Cdd:cd20823 1 HRIPHRFEPFTNLGANWCCHCGQMLPLGRkQIRKCTECGKTAHAQCAHLVPNFCGLSME 59
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
256-750 |
1.08e-10 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 66.85 E-value: 1.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 256 NRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYeekikvldNQIKKDLADKESLENMMQRHEEE 335
Cdd:PRK01156 186 DYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDY--------NNLKSALNELSSLEDMKNRYESE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 336 AHEkgkiLSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQeemISELRQQKFYLETQAGKLEAQNRK 415
Cdd:PRK01156 258 IKT----AESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKND---IENKKQILSNIDAEINKYHAIIKK 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 416 LEEqLEKISHQDHSDKSRLLELETRLREVSLEH-----------------EEQKLELKRQLTELQLSLQERESQLTALQA 478
Cdd:PRK01156 331 LSV-LQKDYNDYIKKKSRYDDLNNQILELEGYEmdynsylksieslkkkiEEYSKNIERMSAFISEILKIQEIDPDAIKK 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 479 ARAALESQLRQakteLEETTAEAEEEIQALTAHRDEIQRKFDAL--RNSCTVI-TDL-EEQLNQLTED-NAELNNQNFYL 553
Cdd:PRK01156 410 ELNEINVKLQD----ISSKVSSLNQRIRALRENLDELSRNMEMLngQSVCPVCgTTLgEEKSNHIINHyNEKKSRLEEKI 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 554 SKQLDEASGANDEIVQLRSEVDHLR-----------REITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEK 622
Cdd:PRK01156 486 REIEIEVKDIDEKIVDLKKRKEYLEseeinksineyNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDS 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 623 ER-QW------------EAWRSVLGDEKSQF---ECRVRELQ--------------RMLDTE------KQSRARADQRIT 666
Cdd:PRK01156 566 KRtSWlnalavislidiETNRSRSNEIKKQLndlESRLQEIEigfpddksyidksiREIENEannlnnKYNEIQENKILI 645
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 667 ESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETER----ELKQRLLEEQAKL 742
Cdd:PRK01156 646 EKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRtrinELSDRINDINETL 725
|
....*...
gi 1039770412 743 QQQMDLQK 750
Cdd:PRK01156 726 ESMKKIKK 733
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
111-543 |
1.34e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 65.94 E-value: 1.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 111 QLEEDLVSARRRSDLY---ESELRESRLAAEEFKRKANECQHKL--MKAKDQGKPEVGEYSKLEKINAEQQLKIQELQEK 185
Cdd:COG4717 75 ELEEELKEAEEKEEEYaelQEELEELEEELEELEAELEELREELekLEKLLQLLPLYQELEALEAELAELPERLEELEER 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 186 LEKAVKASTEATELLQNIRQAKERAERELEKLhnredsSEGIKKKLVEAEERRHSLENKVKRLetmERRENRLKDDIQTK 265
Cdd:COG4717 155 LEELRELEEELEELEAELAELQEELEELLEQL------SLATEEELQDLAEELEELQQRLAEL---EEELEEAQEELEEL 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 266 SEQIQQMADKILELEEKHR-------------------------------------EAQVSAQHLEVHLKQKEQHYEEKI 308
Cdd:COG4717 226 EEELEQLENELEAAALEERlkearlllliaaallallglggsllsliltiagvlflVLGLLALLFLLLAREKASLGKEAE 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 309 KVLDNQIKKDLADKEsLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQ 388
Cdd:COG4717 306 ELQALPALEELEEEE-LEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDE 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 389 EEMISELRQQKFYLETQAgKLEAQNRKLEEQLEKISHQ-DHSDKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQ 467
Cdd:COG4717 385 EELRAALEQAEEYQELKE-ELEELEEQLEELLGELEELlEALDEEELEEELEELEEELEELEEELEELREELAELEAELE 463
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770412 468 ERESQ--LTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKfdalrnsctVITDLEEQLNQLTEDN 543
Cdd:COG4717 464 QLEEDgeLAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPP---------VLERASEYFSRLTDGR 532
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2-454 |
1.34e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 66.24 E-value: 1.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 2 LLGEEAMMEQEMTRLHRRVSEVEAVLSQ---KEVELKASETQRSLLEQDLAtyitecsSLKRSLEqarmevsqEDDKALQ 78
Cdd:PRK03918 305 YLDELREIEKRLSRLEEEINGIEERIKEleeKEERLEELKKKLKELEKRLE-------ELEERHE--------LYEEAKA 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 79 LLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANEC--------QHK 150
Cdd:PRK03918 370 KKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCpvcgreltEEH 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 151 LMKAKDQGKPEVGEYSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAER----ELEKLHNREDSSEG 226
Cdd:PRK03918 450 RKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKlkkyNLEELEKKAEEYEK 529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 227 IKKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKhreaqvSAQHLEVHLKQKEQHYEE 306
Cdd:PRK03918 530 LKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFE------SVEELEERLKELEPFYNE 603
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 307 KIKVLDnqIKKDLadkESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVElsEANKLAANSSLFTQRNMK 386
Cdd:PRK03918 604 YLELKD--AEKEL---EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE--EEYEELREEYLELSRELA 676
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770412 387 AQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSdKSRLLELETRLREVSLEHEEQKLE 454
Cdd:PRK03918 677 GLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKA-LERVEELREKVKKYKALLKERALS 743
|
|
| C1 |
smart00109 |
Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains); Some bind phorbol ... |
931-979 |
1.76e-10 |
|
Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains); Some bind phorbol esters and diacylglycerol. Some bind RasGTP. Zinc-binding domains.
Pssm-ID: 197519 Cd Length: 50 Bit Score: 57.48 E-value: 1.76e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1039770412 931 HRFNVGLNMRATKCAVCLDTVHFGR-QASKCLECQVMCHPKCSTCLPATC 979
Cdd:smart00109 1 HKHVFRTFTKPTFCCVCRKSIWGSFkQGLRCSECKVKCHKKCADKVPKAC 50
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
416-860 |
1.76e-10 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 65.83 E-value: 1.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 416 LEEQLEKISHQDHSDksRLLELETRLREVS--LEH-EEQKLELKRQLTELQLSLQERESQLTALQAARAALEsQLRQAKT 492
Cdd:PRK02224 192 LKAQIEEKEEKDLHE--RLNGLESELAELDeeIERyEEQREQARETRDEADEVLEEHEERREELETLEAEIE-DLRETIA 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 493 ELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTV----ITDLEEQLNQLTEDNAE----LNNQNFYLSKQLDEASGAN 564
Cdd:PRK02224 269 ETEREREELAEEVRDLRERLEELEEERDDLLAEAGLddadAEAVEARREELEDRDEElrdrLEECRVAAQAHNEEAESLR 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 565 DEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQFECRV 644
Cdd:PRK02224 349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 645 RELQRMLDTEKQSRARAD------------QRITESRQVVELAVKEHKAEILALQqaLKEQKLKAESLSDKLN------D 706
Cdd:PRK02224 429 AELEATLRTARERVEEAEalleagkcpecgQPVEGSPHVETIEEDRERVEELEAE--LEDLEEEVEEVEERLEraedlvE 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 707 LEKKHAMLEMNARSLQQKLET-------ERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEY 779
Cdd:PRK02224 507 AEDRIERLEERREDLEELIAErretieeKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKE 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 780 QLENIQVLYS---------------HEKVKMEGTISQQTKliDFLQAKMDqpaKKKKVPLQYNELklALEKEKARCAELE 844
Cdd:PRK02224 587 RIESLERIRTllaaiadaedeierlREKREALAELNDERR--ERLAEKRE---RKRELEAEFDEA--RIEEAREDKERAE 659
|
490
....*....|....*.
gi 1039770412 845 EALQKTRIELRSAREE 860
Cdd:PRK02224 660 EYLEQVEEKLDELREE 675
|
|
| C1 |
cd00029 |
protein kinase C conserved region 1 (C1 domain) superfamily; The C1 domain is a cysteine-rich ... |
931-979 |
1.84e-10 |
|
protein kinase C conserved region 1 (C1 domain) superfamily; The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains. It contains the motif HX12CX2CXnCX2CX4HX2CX7C, where C and H are cysteine and histidine, respectively; X represents other residues; and n is either 13 or 14. C1 has a globular fold with two separate Zn(2+)-binding sites. It was originally discovered as lipid-binding modules in protein kinase C (PKC) isoforms. C1 domains that bind and respond to phorbol esters (PE) and diacylglycerol (DAG) are referred to as typical, and those that do not respond to PE and DAG are deemed atypical. A C1 domain may also be referred to as PKC or non-PKC C1, based on the parent protein's activity. Most C1 domain-containing non-PKC proteins act as lipid kinases and scaffolds, except PKD which acts as a protein kinase. PKC C1 domains play roles in membrane translocation and activation of the enzyme.
Pssm-ID: 410341 Cd Length: 50 Bit Score: 57.53 E-value: 1.84e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1039770412 931 HRFNVGLNMRATKCAVCLDTV-HFGRQASKCLECQVMCHPKCSTCLPATC 979
Cdd:cd00029 1 HRFVPTTFSSPTFCDVCGKLIwGLFKQGLKCSDCGLVCHKKCLDKAPSPC 50
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
304-871 |
2.35e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 65.47 E-value: 2.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 304 YEEKIKVLDNQIKKDLADKESLENMMQRhEEEAHEKgkiLSEQKAMINAMDSKIRSLEQRIVELSEanKLAANSSLFtqR 383
Cdd:PRK03918 160 YENAYKNLGEVIKEIKRRIERLEKFIKR-TENIEEL---IKEKEKELEEVLREINEISSELPELRE--ELEKLEKEV--K 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 384 NMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKIshqdhsdKSRLLELETRLREV-SLEHEEQK-LELKRQLTE 461
Cdd:PRK03918 232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEEL-------KKEIEELEEKVKELkELKEKAEEyIKLSEFYEE 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 462 LQLSLQERESQLTALQAARAALESQLRQAKTELEEttaeaeeeIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTE 541
Cdd:PRK03918 305 YLDELREIEKRLSRLEEEINGIEERIKELEEKEER--------LEELKKKLKELEKRLEELEERHELYEEAKAKKEELER 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 542 DNAELNNQNF-YLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTC-------------TMLEE 607
Cdd:PRK03918 377 LKKRLTGLTPeKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCpvcgrelteehrkELLEE 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 608 QVLDLEALNDELLEkerqweawrsvLGDEKSQFECRVRELQRMLdtEKQSRARADQRITESRQVVELAVKEHKAEilalq 687
Cdd:PRK03918 457 YTAELKRIEKELKE-----------IEEKERKLRKELRELEKVL--KKESELIKLKELAEQLKELEEKLKKYNLE----- 518
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 688 qALKEQKLKAESLSDKLNDLEKKhamlemnARSLQQKLETERELKQRLLEEQAKLQQqmdlqknhifrltqglqealdra 767
Cdd:PRK03918 519 -ELEKKAEEYEKLKEKLIKLKGE-------IKSLKKELEKLEELKKKLAELEKKLDE----------------------- 567
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 768 dlLKTERSDLEYQLENIQVLYSHEkvkMEGTISQQTKLID-FLQAKmdqPAKKKkvpLQYNELKLALEKEKARCAELEEA 846
Cdd:PRK03918 568 --LEEELAELLKELEELGFESVEE---LEERLKELEPFYNeYLELK---DAEKE---LEREEKELKKLEEELDKAFEELA 636
|
570 580
....*....|....*....|....*
gi 1039770412 847 LQKTRIELRSAREEAAHRKATDHPH 871
Cdd:PRK03918 637 ETEKRLEELRKELEELEKKYSEEEY 661
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
2-848 |
2.94e-10 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 65.20 E-value: 2.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 2 LLGEEAMMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSL---KRSLEQARMEVSQEddkalq 78
Cdd:pfam01576 94 LQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLskeRKLLEERISEFTSN------ 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 79 lLHDIREQSRKLQEIKEQeYQAQVEEMRLMMNQLE---EDLVSARRRSDLYESELRES----RLAAEEFKRKANECQHKL 151
Cdd:pfam01576 168 -LAEEEEKAKSLSKLKNK-HEAMISDLEERLKKEEkgrQELEKAKRKLEGESTDLQEQiaelQAQIAELRAQLAKKEEEL 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 152 MKAKDQGKPEVGEYSKLEKINAEQQLKIQELQEKLEkavkasteatellqNIRQAKERAEREleklhnREDSSEgikkkl 231
Cdd:pfam01576 246 QAALARLEEETAQKNNALKKIRELEAQISELQEDLE--------------SERAARNKAEKQ------RRDLGE------ 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 232 vEAEERRHSLENKVKRLETMErrenrlkdDIQTKSEQIQQMADKILELEEKHREAQVSaqhlevhlkQKEQHYEEKIKVL 311
Cdd:pfam01576 300 -ELEALKTELEDTLDTTAAQQ--------ELRSKREQEVTELKKALEEETRSHEAQLQ---------EMRQKHTQALEEL 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 312 DNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVEL-SEANKLAANSSLFTQRNMKAQEE 390
Cdd:pfam01576 362 TEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELqARLSESERQRAELAEKLSKLQSE 441
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 391 ------MISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELE---TRLREVSLEHEEQKLELKRQLTE 461
Cdd:pfam01576 442 lesvssLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEderNSLQEQLEEEEEAKRNVERQLST 521
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 462 LQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQA---------------------------LTAHRDE 514
Cdd:pfam01576 522 LQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAydklektknrlqqelddllvdldhqrqLVSNLEK 601
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 515 IQRKFD-ALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEI----VQLRSEVDHL-------RREIT 582
Cdd:pfam01576 602 KQKKFDqMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELertnKQLRAEMEDLvsskddvGKNVH 681
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 583 EREMQLTSQKQTMEALKTTCTMLEEQvldLEALNDELLEKERQWEAW----------RSVLGDEK-SQFECRVRELQRML 651
Cdd:pfam01576 682 ELERSKRALEQQVEEMKTQLEELEDE---LQATEDAKLRLEVNMQALkaqferdlqaRDEQGEEKrRQLVKQVRELEAEL 758
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 652 DTEKQSRARAdqriTESRQVVELAVKEHKAEILALQQ----ALKEQKLKAESLSDKLNDLEKKHAMLEmnaRSLQQKLET 727
Cdd:pfam01576 759 EDERKQRAQA----VAAKKKLELDLKELEAQIDAANKgreeAVKQLKKLQAQMKDLQRELEEARASRD---EILAQSKES 831
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 728 ERELKQRlleEQAKLQQQMDLQKNHIFRlTQGLQEALDRADLLKTERSDLEYQLEniqvlyshEKVKMEGTISQQTKLID 807
Cdd:pfam01576 832 EKKLKNL---EAELLQLQEDLAASERAR-RQAQQERDELADEIASGASGKSALQD--------EKRRLEARIAQLEEELE 899
|
890 900 910 920
....*....|....*....|....*....|....*....|..
gi 1039770412 808 FLQAKMDQPAKK-KKVPLQYNELKLALEKEKARCAELEEALQ 848
Cdd:pfam01576 900 EEQSNTELLNDRlRKSTLQVEQLTTELAAERSTSQKSESARQ 941
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
325-561 |
3.00e-10 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 65.04 E-value: 3.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 325 LENMMQRHEEEAHEKGKILSEQkamINAMDSKIRSLEQRIVELSEANKLAAnsslfTQRNMKAQEEMISELRQQKFYLET 404
Cdd:COG3206 162 LEQNLELRREEARKALEFLEEQ---LPELRKELEEAEAALEEFRQKNGLVD-----LSEEAKLLLQQLSELESQLAEARA 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 405 QAGKLEAQNRKLEEQLEKISHQ--DHSDKSRLLELETRLREvsleheeqkleLKRQLTELQLSLQERESQLTALQAARAA 482
Cdd:COG3206 234 ELAEAEARLAALRAQLGSGPDAlpELLQSPVIQQLRAQLAE-----------LEAELAELSARYTPNHPDVIALRAQIAA 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 483 LESQLRQAkteLEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDnAELNNQNF-YLSKQLDEAS 561
Cdd:COG3206 303 LRAQLQQE---AQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLERE-VEVARELYeSLLQRLEEAR 378
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
78-682 |
5.97e-10 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 64.55 E-value: 5.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 78 QLLHDIREQSRKLQEIKE--QEYQAQVEEMRLMmNQLEEDLVS--ARRRSDLYESELRESRLAAEEFKRKANECQhklmK 153
Cdd:COG4913 242 EALEDAREQIELLEPIRElaERYAAARERLAEL-EYLRAALRLwfAQRRLELLEAELEELRAELARLEAELERLE----A 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 154 AKDQGKPEVGE---------YSKLEKINAEQQLKIQELQEKLEKA-----------VKASTEATELLQNIRQAKERAERE 213
Cdd:COG4913 317 RLDALREELDEleaqirgngGDRLEQLEREIERLERELEERERRRarleallaalgLPLPASAEEFAALRAEAAALLEAL 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 214 LEKLHNREDSSEGIKKKLVEAEERRHSLENKVKRLE----TMERRENRLKDDIqtkSEQIQQMADKI------LELEEKH 283
Cdd:COG4913 397 EEELEALEEALAEAEAALRDLRRELRELEAEIASLErrksNIPARLLALRDAL---AEALGLDEAELpfvgelIEVRPEE 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 284 REAQ---------------VSAQHL--------EVHLKQK-------------------EQHYEEKIKVLDNQ----IKK 317
Cdd:COG4913 474 ERWRgaiervlggfaltllVPPEHYaaalrwvnRLHLRGRlvyervrtglpdperprldPDSLAGKLDFKPHPfrawLEA 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 318 DLADK------ESLENM-----------MQRHEEEAHEKG---KILSEQ------KAMINAMDSKIRSLEQRIVELSEAN 371
Cdd:COG4913 554 ELGRRfdyvcvDSPEELrrhpraitragQVKGNGTRHEKDdrrRIRSRYvlgfdnRAKLAALEAELAELEEELAEAEERL 633
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 372 KLAANSslftQRNMKAQEEMISELRQQKFYlETQAGKLEAQNRKLEEQLEKIShqdhSDKSRLLELETRLREVSLEH--- 448
Cdd:COG4913 634 EALEAE----LDALQERREALQRLAEYSWD-EIDVASAEREIAELEAELERLD----ASSDDLAALEEQLEELEAELeel 704
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 449 EEQKLELKRQLTELQLSLQERESQLTALQAA------------RAALESQLRQAKTELEETTAEAEEEiQALTAHRDEIQ 516
Cdd:COG4913 705 EEELDELKGEIGRLEKELEQAEEELDELQDRleaaedlarlelRALLEERFAAALGDAVERELRENLE-ERIDALRARLN 783
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 517 RKFDALRN------------SCTVITDLE------EQLNQLTEDNAELNNQNFylSKQLDEASgaNDEIVQLRSEVDHLR 578
Cdd:COG4913 784 RAEEELERamrafnrewpaeTADLDADLEslpeylALLDRLEEDGLPEYEERF--KELLNENS--IEFVADLLSKLRRAI 859
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 579 REITER-----------------EMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKerqweawrsvlgdeksQFE 641
Cdd:COG4913 860 REIKERidplndslkripfgpgrYLRLEARPRPDPEVREFRQELRAVTSGASLFDEELSEA----------------RFA 923
|
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 1039770412 642 cRVREL-QRMLDTEKQSRARADQRITESRQVVELAVKEHKAE 682
Cdd:COG4913 924 -ALKRLiERLRSEEEESDRRWRARVLDVRNHLEFDAEEIDRE 964
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
197-759 |
7.04e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 63.63 E-value: 7.04e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 197 TELLQNIRQA-KERAERELEKLHNREDssegikKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADK 275
Cdd:COG4717 37 STLLAFIRAMlLERLEKEADELFKPQG------RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAE 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 276 ILELEEKHREAQVSAQHLEVHLKQKEqhyeekikvldnqikkdlaDKESLENMMQRHEEeahekgkiLSEQKAMINAMDS 355
Cdd:COG4717 111 LEELREELEKLEKLLQLLPLYQELEA-------------------LEAELAELPERLEE--------LEERLEELRELEE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 356 KIRSLEQRIVELSEA-NKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKIS--HQDHSDKS 432
Cdd:COG4717 164 ELEELEAELAELQEElEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEneLEAAALEE 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 433 RLLELETRLREVSLEHEeqklelkrqLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHR 512
Cdd:COG4717 244 RLKEARLLLLIAAALLA---------LLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALE 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 513 DEIQRKfdalrnsctvitdLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQK 592
Cdd:COG4717 315 ELEEEE-------------LEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGV 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 593 QTMEALKTTCTMLEEQV---LDLEALNDELLEKERQWEAWRSVLGDEksqfecrvrELQRMLDTEKQSRARADQRITESR 669
Cdd:COG4717 382 EDEEELRAALEQAEEYQelkEELEELEEQLEELLGELEELLEALDEE---------ELEEELEELEEELEELEEELEELR 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 670 QvvELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAklqqqmdlq 749
Cdd:COG4717 453 E--ELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERA--------- 521
|
570
....*....|.
gi 1039770412 750 kNHIF-RLTQG 759
Cdd:COG4717 522 -SEYFsRLTDG 531
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
72-670 |
1.12e-09 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 63.40 E-value: 1.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 72 EDDKALQLLHDIreQSRK----LQE-IKEQ-----EYQAQVEEMRLMMNQL---EEDLVSARRRSDLyeseLRESRLAAE 138
Cdd:COG4913 189 GSEKALRLLHKT--QSFKpigdLDDfVREYmleepDTFEAADALVEHFDDLeraHEALEDAREQIEL----LEPIRELAE 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 139 EFKRKANECQHkLMKAKDQGKPEvgeysklekinaEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLH 218
Cdd:COG4913 263 RYAAARERLAE-LEYLRAALRLW------------FAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELE 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 219 NREDSSEGIKKKLVEAEerrhsLENKVKRLETMERRENRLKDDIQT--------------KSEQIQQMADKILELEEKHR 284
Cdd:COG4913 330 AQIRGNGGDRLEQLERE-----IERLERELEERERRRARLEALLAAlglplpasaeefaaLRAEAAALLEALEEELEALE 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 285 EAQVSAQHLEVHLKQKEQHYEEKIKVLDN----------QIKKDLADKESLE--------NMMQRHEEEAHEKGKI---- 342
Cdd:COG4913 405 EALAEAEAALRDLRRELRELEAEIASLERrksniparllALRDALAEALGLDeaelpfvgELIEVRPEEERWRGAIervl 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 343 -------------LSEQKAMINAMDSKIR------------SLEQRIVELSEANKLAANSSLFTQRnmkAQEEM------ 391
Cdd:COG4913 485 ggfaltllvppehYAAALRWVNRLHLRGRlvyervrtglpdPERPRLDPDSLAGKLDFKPHPFRAW---LEAELgrrfdy 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 392 -----ISELRQQKFYLeTQAGKLeAQNRKLEEqlekisHQDHSdksrlleletRLREVSL---EHEEQKLELKRQLTELQ 463
Cdd:COG4913 562 vcvdsPEELRRHPRAI-TRAGQV-KGNGTRHE------KDDRR----------RIRSRYVlgfDNRAKLAALEAELAELE 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 464 LSLQERESQLTALQAARAALESQLRQakteleettaeaeeeIQALTAHRDEIQRKFDALRNsctvITDLEEQLNQLTEDN 543
Cdd:COG4913 624 EELAEAEERLEALEAELDALQERREA---------------LQRLAEYSWDEIDVASAERE----IAELEAELERLDASS 684
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 544 AELNNqnfyLSKQLDEasgANDEIVQLRSEVDHLRREITEREMQLTSqkqtmealkttctmLEEQVLDLEALNDELLEKE 623
Cdd:COG4913 685 DDLAA----LEEQLEE---LEAELEELEEELDELKGEIGRLEKELEQ--------------AEEELDELQDRLEAAEDLA 743
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 1039770412 624 RQW------EAWRSVLGDEKSQfecRVRE-LQRMLDTEKQSRARADQRITESRQ 670
Cdd:COG4913 744 RLElralleERFAAALGDAVER---ELREnLEERIDALRARLNRAEEELERAMR 794
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
2-747 |
1.60e-09 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 62.89 E-value: 1.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 2 LLGEEAMMEQEMTR---LHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQarmevSQEDDKALQ 78
Cdd:pfam01576 245 LQAALARLEEETAQknnALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELED-----TLDTTAAQQ 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 79 LLHDIREQS----RKLQEIKEQEYQAQVEEMRLMMNQ----LEEDLVSARR-RSDL------YESELRESRLAAEEFKRK 143
Cdd:pfam01576 320 ELRSKREQEvtelKKALEEETRSHEAQLQEMRQKHTQaleeLTEQLEQAKRnKANLekakqaLESENAELQAELRTLQQA 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 144 ANECQHKLMKAKDQGKPEVGEYSKLEKINAEQQLKIQELQEKLEKAVKASTEATEllQNIRQAKERAERELEKLHNREDS 223
Cdd:pfam01576 400 KQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEG--KNIKLSKDVSSLESQLQDTQELL 477
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 224 SEGIKKKLV------EAEERRHSLEnkvKRLETMERRENRLKDDIQTKSEQIQQMADKILE-------LEEKHREAQVSA 290
Cdd:pfam01576 478 QEETRQKLNlstrlrQLEDERNSLQ---EQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEdagtleaLEEGKKRLQREL 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 291 QHLEVHLKQKEQHYE--EKIKV-LDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAM-------DSKIRSL 360
Cdd:pfam01576 555 EALTQQLEEKAAAYDklEKTKNrLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYaeerdraEAEAREK 634
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 361 EQRIVELSEANKLAANSSLFTQRNMKAQ----EEMIS----------ELRQQKFYLETQAGKLEAQNRKLEEQLekishQ 426
Cdd:pfam01576 635 ETRALSLARALEEALEAKEELERTNKQLraemEDLVSskddvgknvhELERSKRALEQQVEEMKTQLEELEDEL-----Q 709
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 427 DHSDKSRLLELETRLREVSLEH---------EEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEET 497
Cdd:pfam01576 710 ATEDAKLRLEVNMQALKAQFERdlqardeqgEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAA 789
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 498 TAEAEEEIQAL---TAHRDEIQRKFDALRNSCTVI-----------TDLEEQLNQLTEDNA------------------E 545
Cdd:pfam01576 790 NKGREEAVKQLkklQAQMKDLQRELEEARASRDEIlaqskesekklKNLEAELLQLQEDLAaserarrqaqqerdeladE 869
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 546 LNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREI---TEREMQLTSQKQTME----ALKTTCTMLEEQVLDLEALNDE 618
Cdd:pfam01576 870 IASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTellNDRLRKSTLQVEQLTtelaAERSTSQKSESARQQLERQNKE 949
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 619 LLEKERQWE-AWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITEsrqvvelavKEHKAEILALQqaLKEQKLKA 697
Cdd:pfam01576 950 LKAKLQEMEgTVKSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRR---------TEKKLKEVLLQ--VEDERRHA 1018
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|
gi 1039770412 698 ESLSDKLndlEKKHAMLemnaRSLQQKLETERELKQRLLEEQAKLQQQMD 747
Cdd:pfam01576 1019 DQYKDQA---EKGNSRM----KQLKRQLEEAEEEASRANAARRKLQRELD 1061
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
45-782 |
1.91e-09 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 62.89 E-value: 1.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 45 EQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQeiKEQEYQAQVEEM--RLMMNQLEEDLVSARRR 122
Cdd:pfam01576 4 EEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQ--AETELCAEAEEMraRLAARKQELEEILHELE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 123 SDLYESELRESRLAAEefkRKANECQHKLMKAKDQGKPEVGEYSKLEKINAEQQLK--------IQELQEKLEKAVKAST 194
Cdd:pfam01576 82 SRLEEEEERSQQLQNE---KKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKkleedillLEDQNSKLSKERKLLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 195 EATELLQNIRQAKERAERELEKLHNREDSSegikkkLVEAEERRHSLENKVKRLETMERRENRLKDDIQTK-SEQIQQMA 273
Cdd:pfam01576 159 ERISEFTSNLAEEEEKAKSLSKLKNKHEAM------ISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQiAELQAQIA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 274 DKILELEEKHREAQVSAQHLEVHLKQKEQhYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMI--- 350
Cdd:pfam01576 233 ELRAQLAKKEEELQAALARLEEETAQKNN-ALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELedt 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 351 ---NAMDSKIRS-LEQRIVEL-----SEANKLAANSSLFTQRNMKAQEEMISELRQQKFY---LETQAGKLEAQNRKLEE 418
Cdd:pfam01576 312 ldtTAAQQELRSkREQEVTELkkaleEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNkanLEKAKQALESENAELQA 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 419 QLEKISHQDHSDKSRLLELETRLREVSLEH---EEQKLELKRQLTELQL-------SLQERESQLTALQAARAALESQLR 488
Cdd:pfam01576 392 ELRTLQQAKQDSEHKRKKLEGQLQELQARLsesERQRAELAEKLSKLQSelesvssLLNEAEGKNIKLSKDVSSLESQLQ 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 489 QAKTELEETTAEAEEEIQALTAHRDEiqrkfdalRNSctvitdLEEQLNQLTEDNAE-------LNNQNFYLSKQLDEAS 561
Cdd:pfam01576 472 DTQELLQEETRQKLNLSTRLRQLEDE--------RNS------LQEQLEEEEEAKRNverqlstLQAQLSDMKKKLEEDA 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 562 GANDEIVQLRSEvdhLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDL-------EALNDELLEKERQWE------- 627
Cdd:pfam01576 538 GTLEALEEGKKR---LQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLlvdldhqRQLVSNLEKKQKKFDqmlaeek 614
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 628 AWRSVLGDEKSQFECRVRElqrmLDTEKQSRARADQRITESRQVVELAVKEHKAEI---------------------LAL 686
Cdd:pfam01576 615 AISARYAEERDRAEAEARE----KETRALSLARALEEALEAKEELERTNKQLRAEMedlvsskddvgknvhelerskRAL 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 687 QQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQ-------------------------QKLETER--ELKQRLLEEQ 739
Cdd:pfam01576 691 EQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKaqferdlqardeqgeekrrqlvkqvRELEAELedERKQRAQAVA 770
|
810 820 830 840
....*....|....*....|....*....|....*....|....*
gi 1039770412 740 AKLQQQMDLQ--KNHIFRLTQGLQEALDRADLLKTERSDLEYQLE 782
Cdd:pfam01576 771 AKKKLELDLKelEAQIDAANKGREEAVKQLKKLQAQMKDLQRELE 815
|
|
| ROM1 |
COG5422 |
RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction ... |
1184-1435 |
2.05e-09 |
|
RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms];
Pssm-ID: 227709 [Multi-domain] Cd Length: 1175 Bit Score: 62.60 E-value: 2.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1184 SDQVVLVGTEEGLYALNVLKNS--------LTHIPGIGavfQIYIIKDLEKLLMIAGEERALCLVDVKKVKQSLAQSHLp 1255
Cdd:COG5422 868 SGRKLLTGTNKGLYISNRKDNVnrfnkpidLLQEPNIS---QIIVIEEYKLMLLLSDKKLYSCPLDVIDASTEENVKKS- 943
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1256 aqpDVSPNIFEAVK-----GCHLFAAGKiENSLCICAAMPSKVVILRYNDN------LSKYCIRKEIETSEPCScIHFTN 1324
Cdd:COG5422 944 ---RIVNGHVSFFKqgfcnGKRLVCAVK-SSSLSATLAVIEAPLALKKNKSgnlkkaLTIELSTELYVPSEPLS-VHFLK 1018
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1325 YSILIGTNKFYEI-DMKQYTLDEFLDKNDHSlaPAVFASSSNSFPVSIVQANSagqreEYLLCFHEFGVFVDSYGRRSRT 1403
Cdd:COG5422 1019 NKLCIGCKKGFEIvSLENLRTESLLNPADTS--PLFFEKKENTKPIAIFRVSG-----EFLLCYSEFAFFVNDQGWRKRT 1091
|
250 260 270
....*....|....*....|....*....|...
gi 1039770412 1404 DDL-KWSRLPLAFAYREPYlfVTHFNSlEVIEI 1435
Cdd:COG5422 1092 SWIfHWEGEPQEFALSYPY--ILAFEP-NFIEI 1121
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1-592 |
2.20e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 62.68 E-value: 2.20e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1 MLLGEEAMMEQEMTRLHRRVSEV--EAVLSQKEVELKASETQRSLLEQDLATYITEcsSLKRSLEQARMEVSQEDDKALQ 78
Cdd:pfam02463 385 RLSSAAKLKEEELELKSEEEKEAqlLLELARQLEDLLKEEKKEELEILEEEEESIE--LKQGKLTEEKEELEKQELKLLK 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 79 LLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQlEEDLVSARRRSDLYESELRESR------------------LAAEEF 140
Cdd:pfam02463 463 DELELKKSEDLLKETQLVKLQEQLELLLSRQKL-EERSQKESKARSGLKVLLALIKdgvggriisahgrlgdlgVAVENY 541
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 141 KRKA-NECQHKLMKAKDQGKPEVGEYSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEK--- 216
Cdd:pfam02463 542 KVAIsTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDdkr 621
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 217 -LHNREDSSEGIKKKLVEAE-----ERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSA 290
Cdd:pfam02463 622 aKVVEGILKDTELTKLKESAkakesGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEI 701
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 291 QHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEA 370
Cdd:pfam02463 702 KKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEERE 781
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 371 NKLAANSSLFTQRNMKAQEEMISELRQQKFY-LETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHE 449
Cdd:pfam02463 782 KTEKLKVEEEKEEKLKAQEEELRALEEELKEeAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEE 861
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 450 EQKLELKRQLTELQLSLQERESQLTALQAArAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVI 529
Cdd:pfam02463 862 EITKEELLQELLLKEEELEEQKLKDELESK-EEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEEL 940
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039770412 530 TDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQK 592
Cdd:pfam02463 941 LLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
33-487 |
2.21e-09 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 62.43 E-value: 2.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 33 ELKASETQRSLLEQDLATYITECSSLKRSlEQARMEVSQEDDKALQLlhDIREQSRKLQEIKEQEYQAQVEemrlmmnqL 112
Cdd:pfam05483 339 ELNKAKAAHSFVVTEFEATTCSLEELLRT-EQQRLEKNEDQLKIITM--ELQKKSSELEEMTKFKNNKEVE--------L 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 113 EE-DLVSARRRSDLYESELRESrlAAEEFKRKANECQHkLMKAKDQGKPEVGEYSKLEKINAEQQLK-IQELQEKLEKAV 190
Cdd:pfam05483 408 EElKKILAEDEKLLDEKKQFEK--IAEELKGKEQELIF-LLQAREKEIHDLEIQLTAIKTSEEHYLKeVEDLKTELEKEK 484
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 191 KASTEATE-----LLQNIRQAKERAERELEKLHNREDSSEGIKKKlveaeerrhslENKVKRLETMERRENRLKDDIQTK 265
Cdd:pfam05483 485 LKNIELTAhcdklLLENKELTQEASDMTLELKKHQEDIINCKKQE-----------ERMLKQIENLEEKEMNLRDELESV 553
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 266 SEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIkvldNQIKKDLADKEslENMMQRHEEEAHEKGKILSE 345
Cdd:pfam05483 554 REEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKC----NNLKKQIENKN--KNIEELHQENKALKKKGSAE 627
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 346 QKAMiNAMDSKIRSLEQrivelseanKLAANSSLFTQRNMKAQEEM-ISELRQQKFYLETQAGKLEAQNR-KLEEQLEKI 423
Cdd:pfam05483 628 NKQL-NAYEIKVNKLEL---------ELASAKQKFEEIIDNYQKEIeDKKISEEKLLEEVEKAKAIADEAvKLQKEIDKR 697
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039770412 424 SHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQER-ESQLTALQAARAALESQL 487
Cdd:pfam05483 698 CQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAAlEIELSNIKAELLSLKKQL 762
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
5-480 |
2.26e-09 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 62.15 E-value: 2.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 5 EEAMMEQEMTRLHRRVSEVEAVLSQKEVE---LKASETQRSLLEQD------LATYI----TECSSLKRSLEQARMEVsq 71
Cdd:pfam10174 179 EDWERTRRIAEAEMQLGHLEVLLDQKEKEnihLREELHRRNQLQPDpaktkaLQTVIemkdTKISSLERNIRDLEDEV-- 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 72 EDDKALQLLH-DIREQSRKLQEI---------------------KEQEYQAQVEEMRLMMNQ----------LEEDLVSA 119
Cdd:pfam10174 257 QMLKTNGLLHtEDREEEIKQMEVykshskfmknkidqlkqelskKESELLALQTKLETLTNQnsdckqhievLKESLTAK 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 120 RRRSDLYESELRESRLAAEEFKRKANECQHKLMKAKDQGKPEVGEYSKLEKINAEQQLKIQELQEKLEKAVKASTEATEL 199
Cdd:pfam10174 337 EQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQ 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 200 LQNIRqakeRAERELEKLHNREDSSEGI-------KKKLVEAEERRHSLENKVKR--LETMERRENRLKDDIQTKSEQIQ 270
Cdd:pfam10174 417 LAGLK----ERVKSLQTDSSNTDTALTTleealseKERIIERLKEQREREDRERLeeLESLKKENKDLKEKVSALQPELT 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 271 QMADKILELEEKHREAQVSAQHLEVHLKQKE----QHYEEKIKvLDNQIKK------------DLADK-ESLENMMQRHE 333
Cdd:pfam10174 493 EKESSLIDLKEHASSLASSGLKKDSKLKSLEiaveQKKEECSK-LENQLKKahnaeeavrtnpEINDRiRLLEQEVARYK 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 334 EEAHEKG-------KILSEQKAMINAMDSKIRSLEQRIV-ELSEANKLAANSSLFTQRNMKAQEEMISELRQqkfylETQ 405
Cdd:pfam10174 572 EESGKAQaeverllGILREVENEKNDKDKKIAELESLTLrQMKEQNKKVANIKHGQQEMKKKGAQLLEEARR-----RED 646
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 406 AGKLEAQNRKLEEQLEkishqdhsdksrlleletrlrevSLEHEEQKLE-LKRQLTELQLSLQERESQLTALQAAR 480
Cdd:pfam10174 647 NLADNSQQLQLEELMG-----------------------ALEKTRQELDaTKARLSSTQQSLAEKDGHLTNLRAER 699
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
560-785 |
2.45e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 61.32 E-value: 2.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 560 ASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQ 639
Cdd:COG4942 15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 640 FECRVRELQRMLdtekQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQklkAESLSDKLNDLEKKHAMLEMNAR 719
Cdd:COG4942 95 LRAELEAQKEEL----AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYL---APARREQAEELRADLAELAALRA 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 720 SLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQ 785
Cdd:COG4942 168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
416-861 |
2.76e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 61.71 E-value: 2.76e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 416 LEEQLEKISHQDHSDKSRLLELE-TRLREVSLEHEEQKlELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTEL 494
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPELNlKELKELEEELKEAE-EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 495 EETTAEAEeeIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEA-----SGANDEIVQ 569
Cdd:COG4717 126 QLLPLYQE--LEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLAteeelQDLAEELEE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 570 LRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQ---------------VLDLEALNDELLEKERQWEAWRSVLG 634
Cdd:COG4717 204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEerlkearlllliaaaLLALLGLGGSLLSLILTIAGVLFLVL 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 635 --------DEKSQFECRVRELQRMLDTEKQSRARaDQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLND 706
Cdd:COG4717 284 gllallflLLAREKASLGKEAEELQALPALEELE-EEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 707 LEKKHAMLEMNARSLQQKLETERELKQRL--LEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADL--LKTERSDLEYQLE 782
Cdd:COG4717 363 LQLEELEQEIAALLAEAGVEDEEELRAALeqAEEYQELKEELEELEEQLEELLGELEELLEALDEeeLEEELEELEEELE 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 783 NIqvlyshekvkmEGTISQQTKLIDFLQAKMDQPAKKKkvplQYNELKLALEKEKARCAELEE---ALQKTRIELRSARE 859
Cdd:COG4717 443 EL-----------EEELEELREELAELEAELEQLEEDG----ELAELLQELEELKAELRELAEewaALKLALELLEEARE 507
|
..
gi 1039770412 860 EA 861
Cdd:COG4717 508 EY 509
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
75-860 |
2.80e-09 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 62.37 E-value: 2.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 75 KALQLLHDIRE-QSRKLQEIKE-----QEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRlaaeEFKRKANECQ 148
Cdd:TIGR00606 186 KALETLRQVRQtQGQKVQEHQMelkylKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLK----NRLKEIEHNL 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 149 HKLMKAKDqgkpevgEYSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERA--------ERELEKLhNR 220
Cdd:TIGR00606 262 SKIMKLDN-------EIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREkerelvdcQRELEKL-NK 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 221 EDSSEGIKKKLVEAEERRHSLenKVKRLETMERRENRLKDDIQTKSE--------------------QIQQMADK----- 275
Cdd:TIGR00606 334 ERRLLNQEKTELLVEQGRLQL--QADRHQEHIRARDSLIQSLATRLEldgfergpfserqiknfhtlVIERQEDEaktaa 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 276 --ILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLD---NQIKKDLADKESLENMMQRHEEEAHEKGKILSE-QKAM 349
Cdd:TIGR00606 412 qlCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEkkqEELKFVIKELQQLEGSSDRILELDQELRKAERElSKAE 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 350 INA------------------MDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLeA 411
Cdd:TIGR00606 492 KNSltetlkkevkslqnekadLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYF-P 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 412 QNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRqLTELQLSLQERESQLTALQAARAALES---QLR 488
Cdd:TIGR00606 571 NKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELES-KEEQLSSYEDKLFDVCGSQDEESDLERlkeEIE 649
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 489 QAKTELEETTAEAEEEIQALTAHRDE-------IQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEAS 561
Cdd:TIGR00606 650 KSSKQRAMLAGATAVYSQFITQLTDEnqsccpvCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEML 729
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 562 GandeIVQLR-SEVDHLRREITEREMQLTSQKQTMEALKTTctmLEEQVLDLEALNDELLEKErqwEAWRSVLGDEKSQF 640
Cdd:TIGR00606 730 G----LAPGRqSIIDLKEKEIPELRNKLQKVNRDIQRLKND---IEEQETLLGTIMPEEESAK---VCLTDVTIMERFQM 799
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 641 ECRVRELQRMLDTEKQSRARADQRITESRQVVElaVKEHK-----AEILALQQALKEQKLKAESLSDKLNDLEKKHAMLE 715
Cdd:TIGR00606 800 ELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQ--EKQHEldtvvSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIG 877
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 716 MNARSLQQKLETERElkqrLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLL----KTERSDLEYQLENIqvlyshe 791
Cdd:TIGR00606 878 TNLQRRQQFEEQLVE----LSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELisskETSNKKAQDKVNDI------- 946
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770412 792 KVKMEGTISQQTKLIDFLQAKMDQPAKKKKVPLqyNELKLALEKEKARCAELEEALQKTRIELRSAREE 860
Cdd:TIGR00606 947 KEKVKNIHGYMKDIENKIQDGKDDYLKQKETEL--NTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQ 1013
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
5-463 |
5.22e-09 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 61.22 E-value: 5.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 5 EEAMMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDL------ATYITECSSLKRSLEQARMEVSQEDDKAL- 77
Cdd:TIGR00606 585 EINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKSSKQRAMLAGATAv 664
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 78 --QLLHDIREQSRKLQEIKEQEYQAQvEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKAnECQHKLMKAK 155
Cdd:TIGR00606 665 ysQFITQLTDENQSCCPVCQRVFQTE-AELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLA-PGRQSIIDLK 742
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 156 DQGKPEVGEysKLEKINAEQQLKIQEL--QEKLEKAVKASTEATE-------LLQNIRQAKERAERELEKLHNREDSSEG 226
Cdd:TIGR00606 743 EKEIPELRN--KLQKVNRDIQRLKNDIeeQETLLGTIMPEEESAKvcltdvtIMERFQMELKDVERKIAQQAAKLQGSDL 820
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 227 IKKklveAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKH---REAQVSAQHLEVHLKQKEQH 303
Cdd:TIGR00606 821 DRT----VQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKlqiGTNLQRRQQFEEQLVELSTE 896
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 304 YEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKI-------RSLEQRIVE---------L 367
Cdd:TIGR00606 897 VQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVknihgymKDIENKIQDgkddylkqkE 976
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 368 SEANKLAANSSLFTQRNMKAQEEM------ISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLE----- 436
Cdd:TIGR00606 977 TELNTVNAQLEECEKHQEKINEDMrlmrqdIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQmkqeh 1056
|
490 500 510
....*....|....*....|....*....|....*....
gi 1039770412 437 --LETRLREVSLEH----------EEQKLELKRQLTELQ 463
Cdd:TIGR00606 1057 qkLEENIDLIKRNHvlalgrqkgyEKEIKHFKKELREPQ 1095
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
409-851 |
5.42e-09 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 60.08 E-value: 5.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 409 LEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEeqklELKRQLTELQLSLQERESQLTALQAARAALESQLR 488
Cdd:pfam19220 25 LKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYG----KLRRELAGLTRRLSAAEGELEELVARLAKLEAALR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 489 QAKTELEETTAeaeeeiqaltahrdeiqrkfdALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASgandeiv 568
Cdd:pfam19220 101 EAEAAKEELRI---------------------ELRDKTAQAEALERQLAAETEQNRALEEENKALREEAQAAE------- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 569 QLRSEVDHLRREITEREMQLTSQKQTMEALkttctmLEEQVLDLEALNDELLEKERQWEAWRSvlgdeksqfecRVRELQ 648
Cdd:pfam19220 153 KALQRAEGELATARERLALLEQENRRLQAL------SEEQAAELAELTRRLAELETQLDATRA-----------RLRALE 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 649 RMLDTEKQSRARADQRItesrqvvELAVKEHKAEILALqqalkeqKLKAESLSDKLNDLEKkhaMLEMNARSLQQKLETE 728
Cdd:pfam19220 216 GQLAAEQAERERAEAQL-------EEAVEAHRAERASL-------RMKLEALTARAAATEQ---LLAEARNQLRDRDEAI 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 729 RELKQRLLEEQ----------AKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIqvlyshekvkmEGT 798
Cdd:pfam19220 279 RAAERRLKEASierdtlerrlAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKDAALERA-----------EER 347
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 1039770412 799 ISQQTKLIDFLQAKMDQpaKKKKVPLQYNELKLALEKEKARCAELEEALQKTR 851
Cdd:pfam19220 348 IASLSDRIAELTKRFEV--ERAALEQANRRLKEELQRERAERALAQGALEIAR 398
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
200-786 |
5.84e-09 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 61.01 E-value: 5.84e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 200 LQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSlenkvkRLETMERRENRLKDDIQTKSEQIQQMADKiLEL 279
Cdd:pfam12128 236 IMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIAS------RQEERQETSAELNQLLRTLDDQWKEKRDE-LNG 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 280 EEKHREAQVSA--QHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKI 357
Cdd:pfam12128 309 ELSAADAAVAKdrSELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQN 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 358 RSLEQRIVELSEANKLAANSSLFTQRNMKAQEEmiSELRQQkfyletqagkLEAQNRKLEEQLEKIshqdhsdKSRLLEL 437
Cdd:pfam12128 389 NRDIAGIKDKLAKIREARDRQLAVAEDDLQALE--SELREQ----------LEAGKLEFNEEEYRL-------KSRLGEL 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 438 ETRLREVSLEHEEqklelKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEettaeaeeeiQALTAHRDEIQR 517
Cdd:pfam12128 450 KLRLNQATATPEL-----LLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRD----------QASEALRQASRR 514
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 518 kfdalrnsctvitdLEEQLNQLTEDNAELNNQNFYLSKQL-DEASGANDEIVQLRSEvDHLRREITEREMQLTSQKQTME 596
Cdd:pfam12128 515 --------------LEERQSALDELELQLFPQAGTLLHFLrKEAPDWEQSIGKVISP-ELLHRTDLDPEVWDGSVGGELN 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 597 ALKTTCTMLEEQVLDLEALNDELLEKERQWEawrSVLGDEKS---QFECRVRELQRMLDTEKQSRARADQRITESRQVVE 673
Cdd:pfam12128 580 LYGVKLDLKRIDVPEWAASEEELRERLDKAE---EALQSAREkqaAAEEQLVQANGELEKASREETFARTALKNARLDLR 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 674 LAVKEHKAEILALQQALKEQKLKAE----SLSDKLNDLEKKH-AMLEMNARSLQ----QKLETERELKQRLLEEQAKLQQ 744
Cdd:pfam12128 657 RLFDEKQSEKDKKNKALAERKDSANerlnSLEAQLKQLDKKHqAWLEEQKEQKReartEKQAYWQVVEGALDAQLALLKA 736
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 1039770412 745 QMDLQKNHIFRLTQGLQEALDRaDL------------LKTERSDLEYQLENIQV 786
Cdd:pfam12128 737 AIAARRSGAKAELKALETWYKR-DLaslgvdpdviakLKREIRTLERKIERIAV 789
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2-338 |
7.86e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 60.85 E-value: 7.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 2 LLGEEAMMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYI-------TECSSLKRSLEQARMEVSQEDD 74
Cdd:TIGR02169 686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKerleeleEDLSSLEQEIENVKSELKELEA 765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 75 KALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKLMKA 154
Cdd:TIGR02169 766 RIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDL 845
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 155 KDQGKpevgeysKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEgikkklVEA 234
Cdd:TIGR02169 846 KEQIK-------SIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE------AQI 912
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 235 EERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADkILELEEKHREAQVSAQHLE-VHLKQKEQHYEEKIKVLDN 313
Cdd:TIGR02169 913 EKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELS-LEDVQAELQRVEEEIRALEpVNMLAIQEYEEVLKRLDEL 991
|
330 340
....*....|....*....|....*..
gi 1039770412 314 QIKKD--LADKESLENMMQRHEEEAHE 338
Cdd:TIGR02169 992 KEKRAklEEERKAILERIEEYEKKKRE 1018
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
172-856 |
1.30e-08 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 59.84 E-value: 1.30e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 172 NAEQQLKIQELQEKLekavKASTEATELLQNIRQAKERAEREleKLHNREDSSEGIKKKLVEAEERRHSLENKVKRLETM 251
Cdd:pfam10174 69 NQHLQLTIQALQDEL----RAQRDLNQLLQQDFTTSPVDGED--KFSTPELTEENFRRLQSEHERQAKELFLLRKTLEEM 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 252 ERRENRLKDDIQTKSEQIQQMAD--------KILELEEKHR-----EAQVSAQHLEVHLKQKEqhyeekikvldnqiKKD 318
Cdd:pfam10174 143 ELRIETQKQTLGARDESIKKLLEmlqskglpKKSGEEDWERtrriaEAEMQLGHLEVLLDQKE--------------KEN 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 319 LADKESLENMMQRHEEEAHEKGkilseQKAMINAMDSKIRSLEQRIVELS-EANKLAANSSLFTqrnmkaqEEMISELRQ 397
Cdd:pfam10174 209 IHLREELHRRNQLQPDPAKTKA-----LQTVIEMKDTKISSLERNIRDLEdEVQMLKTNGLLHT-------EDREEEIKQ 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 398 QKFYletqagkleaqnrkleeqlekishQDHSDKsrlleletrlrevsleheeqkleLKRQLTELQLSLQERESQLTALQ 477
Cdd:pfam10174 277 MEVY------------------------KSHSKF-----------------------MKNKIDQLKQELSKKESELLALQ 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 478 AARAALESQLRQAKTELEETTaeaeeeiQALTAHRDE---IQRKFDALRNSC----TVITDLEEQLNQLTEDNAELNNQN 550
Cdd:pfam10174 310 TKLETLTNQNSDCKQHIEVLK-------ESLTAKEQRaaiLQTEVDALRLRLeekeSFLNKKTKQLQDLTEEKSTLAGEI 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 551 FYLSKQLDEAsgaNDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEalnDELLEKERQWEAWR 630
Cdd:pfam10174 383 RDLKDMLDVK---ERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLE---EALSEKERIIERLK 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 631 svlgdEKSQFECRVR--ELQRMLDTEKQSRARAD--QRITESRQVVELAVKEHkAEILALQQALKEQKLKA--------- 697
Cdd:pfam10174 457 -----EQREREDRERleELESLKKENKDLKEKVSalQPELTEKESSLIDLKEH-ASSLASSGLKKDSKLKSleiaveqkk 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 698 ESLSDKLNDLEKKHAMlEMNARSLQQKLETERELKQ---RLLEEQAKLQQQMDlqknhifRLTQGLQEAldradllKTER 774
Cdd:pfam10174 531 EECSKLENQLKKAHNA-EEAVRTNPEINDRIRLLEQevaRYKEESGKAQAEVE-------RLLGILREV-------ENEK 595
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 775 SDLEYQLENIQVLYShEKVKMEGTISQQTKLIDFLQ----AKMDQPAKKKKVPLQYNELKLALEkekarcaELEEALQKT 850
Cdd:pfam10174 596 NDKDKKIAELESLTL-RQMKEQNKKVANIKHGQQEMkkkgAQLLEEARRREDNLADNSQQLQLE-------ELMGALEKT 667
|
....*.
gi 1039770412 851 RIELRS 856
Cdd:pfam10174 668 RQELDA 673
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
10-238 |
1.48e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.62 E-value: 1.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 10 EQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRK 89
Cdd:COG4942 26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 90 LQE-IKEQEYQAQVEEMRLMMNQleEDLVSARRRSDLYESELRESRLAAEEFKRKANEcqhkLMKAKDQgkpevgeyskL 168
Cdd:COG4942 106 LAElLRALYRLGRQPPLALLLSP--EDFLDAVRRLQYLKYLAPARREQAEELRADLAE----LAALRAE----------L 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 169 EKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERR 238
Cdd:COG4942 170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
204-881 |
1.53e-08 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 59.60 E-value: 1.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 204 RQAKERAE--RELEKLHNREDSSEGIKKKLVEAEERRHSLEnkvKRLETMERRENRLKDDIQTKSEqiqqmadkILELEE 281
Cdd:TIGR00618 160 AKSKEKKEllMNLFPLDQYTQLALMEFAKKKSLHGKAELLT---LRSQLLTLCTPCMPDTYHERKQ--------VLEKEL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 282 KH-REAQVSAQHLEVHLKQKEQHYEEKIKvLDNQIKKDLADKESLENMMQRHE------EEAHEKGKILSEQKAMINaMD 354
Cdd:TIGR00618 229 KHlREALQQTQQSHAYLTQKREAQEEQLK-KQQLLKQLRARIEELRAQEAVLEetqeriNRARKAAPLAAHIKAVTQ-IE 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 355 SKIRSLEQRIVElseanKLAANSSLFTQRNMKAQEEmiSELRQQKFYLETqagkLEAQNRKLEEQLEK-ISHQDHSDKSR 433
Cdd:TIGR00618 307 QQAQRIHTELQS-----KMRSRAKLLMKRAAHVKQQ--SSIEEQRRLLQT----LHSQEIHIRDAHEVaTSIREISCQQH 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 434 LLELETRLREVSLEHEEQKLELKRQLTElqlSLQERESQLTALQAARAALESQLRQAKTEleettaeaeeeiQALTAHRD 513
Cdd:TIGR00618 376 TLTQHIHTLQQQKTTLTQKLQSLCKELD---ILQREQATIDTRTSAFRDLQGQLAHAKKQ------------QELQQRYA 440
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 514 EIQRKFdalrnsctvitdLEEQLNQLTEDNAELNNqnfylskqldeasgandeivqlrsevdhLRREITEREMQLTSQKQ 593
Cdd:TIGR00618 441 ELCAAA------------ITCTAQCEKLEKIHLQE----------------------------SAQSLKEREQQLQTKEQ 480
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 594 TMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRsVLGDEKSQFECRVRELQRMLDTEKQSRARAD---QRITESRQ 670
Cdd:TIGR00618 481 IHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPAR-QDIDNPGPLTRRMQRGEQTYAQLETSEEDVYhqlTSERKQRA 559
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 671 VVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKkhaMLEMNARSLQQKLETERELKQRLLEEQAKLQ------- 743
Cdd:TIGR00618 560 SLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQD---LTEKLSEAEDMLACEQHALLRKLQPEQDLQDvrlhlqq 636
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 744 --QQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYqLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKK 821
Cdd:TIGR00618 637 csQELALKLTALHALQLTLTQERVREHALSIRVLPKEL-LASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEE 715
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 822 VPLQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKATDHPHPSTPATARQQ 881
Cdd:TIGR00618 716 YDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQ 775
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
577-883 |
2.30e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 59.18 E-value: 2.30e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 577 LRREITEREMQLTSQKqtMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQ 656
Cdd:COG1196 218 LKEELKELEAELLLLK--LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 657 SRARADQRItesrQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKL----ETERELK 732
Cdd:COG1196 296 ELARLEQDI----ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELaeaeEALLEAE 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 733 QRLLEEQAKLQQqmdlQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAK 812
Cdd:COG1196 372 AELAEAEEELEE----LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770412 813 MDQPAKKKKVPLQYNELKLALEKEKARCAELEEALQKTRIELRSaREEAAHRKATDHPHPSTPATARQQIA 883
Cdd:COG1196 448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA-RLLLLLEAEADYEGFLEGVKAALLLA 517
|
|
| C1_KSR |
cd20812 |
protein kinase C conserved region 1 (C1 domain) found in the kinase suppressor of Ras (KSR) ... |
929-980 |
2.37e-08 |
|
protein kinase C conserved region 1 (C1 domain) found in the kinase suppressor of Ras (KSR) family; KSR is a scaffold protein that functions downstream of Ras and upstream of Raf in the Extracellular signal-Regulated Kinase (ERK) pathway that regulates many cellular processes including cycle regulation, proliferation, differentiation, survival, and apoptosis. KSR proteins regulate the assembly and activation of the Raf/MEK/ERK module upon Ras activation at the membrane by direct association of its components. They are widely regarded as pseudokinases, but there is some debate in this designation as a few groups have reported detecting kinase catalytic activity for KSRs, specifically KSR1. Vertebrates contain two KSR proteins, KSR1 and KSR2. KSR proteins contain a SAM-like domain, a zinc finger cysteine-rich domain (C1), and a pseudokinase domain. This model describes the C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410362 Cd Length: 48 Bit Score: 51.56 E-value: 2.37e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1039770412 929 IPHRFNVGLNMRATkCAVCLDTVHFGRqasKCLECQVMCHPKCSTCLPATCG 980
Cdd:cd20812 1 IKHRFSKKLFMRQT-CDYCHKQMFFGL---KCKDCKYKCHKKCAKKAPPSCG 48
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
175-423 |
3.75e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.47 E-value: 3.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 175 QQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLhnrEDSSEGIKKKLVEAEERRHSLENKVKRLetmERR 254
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL---ERRIAALARRIRALEQELAALEAELAEL---EKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 255 ENRLKDDIQTKSEQIQQMAdkileleekhREAQVSAQHlevhlkqkeqhyeEKIKVLDNQikKDLADKESLENMMQRHEE 334
Cdd:COG4942 92 IAELRAELEAQKEELAELL----------RALYRLGRQ-------------PPLALLLSP--EDFLDAVRRLQYLKYLAP 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 335 EAHEKGKILSEQKAMINAmdsKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNR 414
Cdd:COG4942 147 ARREQAEELRADLAELAA---LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223
|
....*....
gi 1039770412 415 KLEEQLEKI 423
Cdd:COG4942 224 ELEALIARL 232
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
373-625 |
4.71e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.08 E-value: 4.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 373 LAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKIShqdhsdkSRLLELETRLREVslehEEQK 452
Cdd:COG4942 10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALE-------RRIAALARRIRAL----EQEL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 453 LELKRQLTELQLSLQERESQLTALqaaRAALESQLRQAKTELEETTAeaeeeiqALTAHRDEIQRKFDALRNSCTVITDL 532
Cdd:COG4942 79 AALEAELAELEKEIAELRAELEAQ---KEELAELLRALYRLGRQPPL-------ALLLSPEDFLDAVRRLQYLKYLAPAR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 533 EEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEvdhLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDL 612
Cdd:COG4942 149 REQAEELRADLAELAALRAELEAERAELEALLAELEEERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEEL 225
|
250
....*....|...
gi 1039770412 613 EALNDELLEKERQ 625
Cdd:COG4942 226 EALIARLEAEAAA 238
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
10-780 |
5.06e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 58.13 E-value: 5.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 10 EQEMTRLHRRVSEVEA---VLSQKEVELKASETQRSLLEQdlatyITECSSLKRSLEQARMEVSQEDDkALQLLHDIREQ 86
Cdd:TIGR00606 318 ERELVDCQRELEKLNKerrLLNQEKTELLVEQGRLQLQAD-----RHQEHIRARDSLIQSLATRLELD-GFERGPFSERQ 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 87 SRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESEL----RESRLAAEEFKRKANECQHK------------ 150
Cdd:TIGR00606 392 IKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKkglgRTIELKKEILEKKQEELKFVikelqqlegssd 471
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 151 -LMKAKDQGKPEVGEYSKLEKINAEQQLKIQELQEKLEKA------------------VKASTEATELL--------QNI 203
Cdd:TIGR00606 472 rILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKAdldrklrkldqemeqlnhHTTTRTQMEMLtkdkmdkdEQI 551
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 204 RQAKERAERELEKL----HNREDSSEGIKKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILEL 279
Cdd:TIGR00606 552 RKIKSRHSDELTSLlgyfPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDV 631
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 280 eekhreaqVSAQHLEVHLKQKEQHYEEKIK----------VLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAM 349
Cdd:TIGR00606 632 --------CGSQDEESDLERLKEEIEKSSKqramlagataVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSK 703
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 350 INAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHS 429
Cdd:TIGR00606 704 LRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEES 783
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 430 DKSRLLELeTRLREVSLEHEEQKLELKRQLTELQLSLQERESQltalqaaraalesQLRQAKTELEETTaeaeeeiqalt 509
Cdd:TIGR00606 784 AKVCLTDV-TIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQ-------------QVNQEKQEKQHEL----------- 838
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 510 ahrDEIQRKFDALRNsctVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLT 589
Cdd:TIGR00606 839 ---DTVVSKIELNRK---LIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDS 912
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 590 SQKQTMEalkttctmleeqvlDLEALNDELLEKERQweawrsvlgdEKSQFECRVRELQRMLDTEKQSRARADQRITESR 669
Cdd:TIGR00606 913 PLETFLE--------------KDQQEKEELISSKET----------SNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGK 968
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 670 qvvELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKL----------ETERELKQRLLE-- 737
Cdd:TIGR00606 969 ---DDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLtlrkrenelkEVEEELKQHLKEmg 1045
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|..
gi 1039770412 738 ---------EQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQ 780
Cdd:TIGR00606 1046 qmqvlqmkqEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFR 1097
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
383-778 |
5.07e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 57.86 E-value: 5.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 383 RNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISH--QDHSDKSRLLELETRLREVSlEHEEQKLELKRQLT 460
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEElrEELEKLEKLLQLLPLYQELE-ALEAELAELPERLE 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 461 ELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSctvITDLEEQLNQLT 540
Cdd:COG4717 150 ELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEE---LEEAQEELEELE 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 541 EDNAELNNQ--NFYLSKQLDEA-------------SGAND----------EIVQLRSEVDHLRREITEREMQLTSQKQTM 595
Cdd:COG4717 227 EELEQLENEleAAALEERLKEArlllliaaallalLGLGGsllsliltiaGVLFLVLGLLALLFLLLAREKASLGKEAEE 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 596 EALKTTCTMLEEQV---------LDLEALNDELLEKERQWEAWRSVL-----GDEKSQFECRVRELQRMLDTEK-QSRAR 660
Cdd:COG4717 307 LQALPALEELEEEEleellaalgLPPDLSPEELLELLDRIEELQELLreaeeLEEELQLEELEQEIAALLAEAGvEDEEE 386
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 661 ADQRITESRQVVELavkehKAEILALQQALKEQKLKAESLSDKLNDlekkhAMLEMNARSLQQKLETERELKQRLLEEQA 740
Cdd:COG4717 387 LRAALEQAEEYQEL-----KEELEELEEQLEELLGELEELLEALDE-----EELEEELEELEEELEELEEELEELREELA 456
|
410 420 430
....*....|....*....|....*....|....*...
gi 1039770412 741 KLQQQMDLQKNhifrlTQGLQEALDRADLLKTERSDLE 778
Cdd:COG4717 457 ELEAELEQLEE-----DGELAELLQELEELKAELRELA 489
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
666-860 |
5.46e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.08 E-value: 5.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 666 TESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQ 745
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 746 MDLQKNHIFRLTQGLQ--EALDRADLLKTERS--DLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKK 821
Cdd:COG4942 99 LEAQKEELAELLRALYrlGRQPPLALLLSPEDflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178
|
170 180 190
....*....|....*....|....*....|....*....
gi 1039770412 822 VPLQYNELKLALEKEKARCAELEEALQKTRIELRSAREE 860
Cdd:COG4942 179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAE 217
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
58-746 |
7.06e-08 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 57.54 E-value: 7.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 58 LKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQeyqaqVEEMRLMMNQLEEDLVSARRRSdlyeselrESRLaa 137
Cdd:pfam12128 214 PKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNT-----LESAELRLSHLHFGYKSDETLI--------ASRQ-- 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 138 EEFKRKANECQHKLMKAKDQGKPEVGEysklekinAEQQLKIQElqekleKAVKASTEATELLQNirQAKERAERELEKL 217
Cdd:pfam12128 279 EERQETSAELNQLLRTLDDQWKEKRDE--------LNGELSAAD------AAVAKDRSELEALED--QHGAFLDADIETA 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 218 HNREDSSEGIKKKLVEAEERRHSLENKVKRLE-TMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSA-QHLEV 295
Cdd:pfam12128 343 AADQEQLPSWQSELENLEERLKALTGKHQDVTaKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDlQALES 422
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 296 HLKQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAA 375
Cdd:pfam12128 423 ELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRD 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 376 NSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKlEEQLEKISHQDHSDKSRLL--ELETRLREVSLEHEEQ-- 451
Cdd:pfam12128 503 QASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRK-EAPDWEQSIGKVISPELLHrtDLDPEVWDGSVGGELNly 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 452 --KLELKR----QLTELQLSLQERESQL-TALQAAR---AALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDA 521
Cdd:pfam12128 582 gvKLDLKRidvpEWAASEEELRERLDKAeEALQSARekqAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDE 661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 522 LRNSCTVITD--------LEEQLNQL-TEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVdhlrreITEREMQLTSQK 592
Cdd:pfam12128 662 KQSEKDKKNKalaerkdsANERLNSLeAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVV------EGALDAQLALLK 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 593 QTMEALKTTctmLEEQVLDLEALNDELLEKerqweawRSVLGDEKSQFECRVRELQRMLDTEKQSRaradQRITESRQVV 672
Cdd:pfam12128 736 AAIAARRSG---AKAELKALETWYKRDLAS-------LGVDPDVIAKLKREIRTLERKIERIAVRR----QEVLRYFDWY 801
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770412 673 ELAVKEHKaeilalqQALKEQKLKAESlsdKLNDLEKKHAMLEMNARSLQQKLETER----ELKQRLLEEQAKLQQQM 746
Cdd:pfam12128 802 QETWLQRR-------PRLATQLSNIER---AISELQQQLARLIADTKLRRAKLEMERkaseKQQVRLSENLRGLRCEM 869
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
513-792 |
7.85e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 57.62 E-value: 7.85e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 513 DEIQRKFDALRNSCTVITDLEEQLNQLTEdnaelnnqnfyLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLtsQK 592
Cdd:COG4913 228 DALVEHFDDLERAHEALEDAREQIELLEP-----------IRELAERYAAARERLAELEYLRAALRLWFAQRRLEL--LE 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 593 QTMEALKTTCTMLEEQVLDLEALNDELLEKERQWE-AWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRItesrQV 671
Cdd:COG4913 295 AELEELRAELARLEAELERLEARLDALREELDELEaQIRGNGGDRLEQLEREIERLERELEERERRRARLEALL----AA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 672 VELAVKEHKAEILALQQALKEQKLKAESLSDKlndlekkhamlemnarsLQQKLETERELKQRLLEEQAKLQQQMDLQKN 751
Cdd:COG4913 371 LGLPLPASAEEFAALRAEAAALLEALEEELEA-----------------LEEALAEAEAALRDLRRELRELEAEIASLER 433
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1039770412 752 HIFRLTQGLQEALDR-ADLLKTERSDLEYQLENIQVLYSHEK 792
Cdd:COG4913 434 RKSNIPARLLALRDAlAEALGLDEAELPFVGELIEVRPEEER 475
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
515-747 |
8.04e-08 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 57.33 E-value: 8.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 515 IQRKFDALRNSctvITDLEEQLNQLTE--DNAELNNQNFYLSKQL----DEASGANDEIVQLRSEVDHLRREITEREMQL 588
Cdd:COG3206 166 LELRREEARKA---LEFLEEQLPELRKelEEAEAALEEFRQKNGLvdlsEEAKLLLQQLSELESQLAEARAELAEAEARL 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 589 TSQKQTMEALKTTCTMLEEQVLdLEALNDELLEKERQWEAWRSVLGDEKSQfecrVRELQRMLDTEKQSRARADQRITES 668
Cdd:COG3206 243 AALRAQLGSGPDALPELLQSPV-IQQLRAQLAELEAELAELSARYTPNHPD----VIALRAQIAALRAQLQQEAQRILAS 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 669 RQVvelAVKEHKAEILALQQALKEQKLKAESLSDKLNDLekkhamlemnaRSLQQKLETERELKQRLLE--EQAKLQQQM 746
Cdd:COG3206 318 LEA---ELEALQAREASLQAQLAQLEARLAELPELEAEL-----------RRLEREVEVARELYESLLQrlEEARLAEAL 383
|
.
gi 1039770412 747 D 747
Cdd:COG3206 384 T 384
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
440-766 |
8.27e-08 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 57.27 E-value: 8.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 440 RLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAkteleettAEAEEEIQALTAHRDEIQRKF 519
Cdd:COG3096 282 ELSERALELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAA--------SDHLNLVQTALRQQEKIERYQ 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 520 DALrnsctviTDLEEQLNQLTEDNAELNNQnfyLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALK 599
Cdd:COG3096 354 EDL-------EELTERLEEQEEVVEEAAEQ---LAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALE 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 600 TTCTMLEEQVLDLEALNDELLE-KERQWEAWRSVLGDE---------KSQFECRVRELQRMLDTEKQSRA--RADQRITE 667
Cdd:COG3096 424 KARALCGLPDLTPENAEDYLAAfRAKEQQATEEVLELEqklsvadaaRRQFEKAYELVCKIAGEVERSQAwqTARELLRR 503
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 668 SRQVVELAVKEH--KAEILALQQALKEQKlKAESLsdkLNDLEKKHA-------MLEMNARSLQQKLETERELKQRLLEE 738
Cdd:COG3096 504 YRSQQALAQRLQqlRAQLAELEQRLRQQQ-NAERL---LEEFCQRIGqqldaaeELEELLAELEAQLEELEEQAAEAVEQ 579
|
330 340 350
....*....|....*....|....*....|....
gi 1039770412 739 QAKLQQQMDLQKNHIFRLTQ------GLQEALDR 766
Cdd:COG3096 580 RSELRQQLEQLRARIKELAArapawlAAQDALER 613
|
|
| PH |
pfam00169 |
PH domain; PH stands for pleckstrin homology. |
1012-1131 |
8.74e-08 |
|
PH domain; PH stands for pleckstrin homology.
Pssm-ID: 459697 [Multi-domain] Cd Length: 105 Bit Score: 51.79 E-value: 8.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1012 LHLEGWMKVPRNNKRGqqGWDRKYIVLEGSKVLIYDNEAREAGQRPVeefelclpdGDVSIHGAVgASELANTAKADVPY 1091
Cdd:pfam00169 1 VVKEGWLLKKGGGKKK--SWKKRYFVLFDGSLLYYKDDKSGKSKEPK---------GSISLSGCE-VVEVVASDSPKRKF 68
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1039770412 1092 ILKMESHPHTtcwPGRTLYLLAPSFPDKQRWVTALESVVA 1131
Cdd:pfam00169 69 CFELRTGERT---GKRTYLLQAESEEERKDWIKAIQSAIR 105
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
297-491 |
9.01e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 56.31 E-value: 9.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 297 LKQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELS---EANKL 373
Cdd:COG4942 25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRaelEAQKE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 374 AANSSLFTQRNMKAQEEMISELRQQKFY-LETQAGKLEAQNRKLEEQLEKIshqdHSDKSRLLELETRLREVSLEHEEQK 452
Cdd:COG4942 105 ELAELLRALYRLGRQPPLALLLSPEDFLdAVRRLQYLKYLAPARREQAEEL----RADLAELAALRAELEAERAELEALL 180
|
170 180 190
....*....|....*....|....*....|....*....
gi 1039770412 453 LELKRQLTELQLSLQERESQLTALQAARAALESQLRQAK 491
Cdd:COG4942 181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQ 219
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
6-301 |
1.10e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 56.67 E-value: 1.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 6 EAMMEQEMTRLHRRVSEVEAVLSQKEVELK--ASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLhdi 83
Cdd:pfam17380 322 EKARQAEMDRQAAIYAEQERMAMERERELEriRQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQEL--- 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 84 rEQSRKlQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLaaEEFKRKANECQHKLMKAKDQGKPEVG 163
Cdd:pfam17380 399 -EAARK-VKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREM--ERVRLEEQERQQQVERLRQQEEERKR 474
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 164 EYSKLEKINAEQQLKIQELQEKLEKAVKASTEATellqnirQAKERAERELEKlhnredSSEGIKKKLVEAEERRHSLEN 243
Cdd:pfam17380 475 KKLELEKEKRDRKRAEEQRRKILEKELEERKQAM-------IEEERKRKLLEK------EMEERQKAIYEEERRREAEEE 541
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770412 244 KVKRLETMERREnrlkddIQtksEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKE 301
Cdd:pfam17380 542 RRKQQEMEERRR------IQ---EQMRKATEERSRLEAMEREREMMRQIVESEKARAE 590
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
2-366 |
1.63e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 56.20 E-value: 1.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 2 LLGEEAMMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATY----------ITECSSLKRSLEQARMEVSQ 71
Cdd:PRK02224 347 LREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELrerfgdapvdLGNAEDFLEELREERDELRE 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 72 ---EDDKALQLLHDIREQSRKL----------QEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELREsrlaAE 138
Cdd:PRK02224 427 reaELEATLRTARERVEEAEALleagkcpecgQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLER----AE 502
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 139 EFKRKANECQHKLMKAKDQGKpevgEYSKLEKINAEQQLKIQELQEKLE----KAVKASTEATELLQNIRQAKERA---E 211
Cdd:PRK02224 503 DLVEAEDRIERLEERREDLEE----LIAERRETIEEKRERAEELRERAAeleaEAEEKREAAAEAEEEAEEAREEVaelN 578
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 212 RELEKLHNREDSSEGIKKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILE--LEEKHREAQVS 289
Cdd:PRK02224 579 SKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEarIEEAREDKERA 658
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 290 AQHLEvHLKQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHE--EEAHEKGKILSEQKAMINAMDSKIRS-LEQRIVE 366
Cdd:PRK02224 659 EEYLE-QVEEKLDELREERDDLQAEIGAVENELEELEELRERREalENRVEALEALYDEAEELESMYGDLRAeLRQRNVE 737
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
260-490 |
1.91e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.16 E-value: 1.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 260 DDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQhyeeKIKVLDNQIKKDLADKESLENMMQRHEEEAHEK 339
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALER----RIAALARRIRALEQELAALEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 340 GKILSEQKAMinamdskirsLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQ 419
Cdd:COG4942 96 RAELEAQKEE----------LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAAL 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770412 420 LEKISHQdhsdKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQA 490
Cdd:COG4942 166 RAELEAE----RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
507-861 |
2.73e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 55.43 E-value: 2.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 507 ALTAHRDEIQRKFDAlrNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREM 586
Cdd:PRK02224 188 SLDQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRE 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 587 QLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQS--------- 657
Cdd:PRK02224 266 TIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAaqahneeae 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 658 --RARADQRITESRQVVELAvKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEM---NARSLQQKLETER-EL 731
Cdd:PRK02224 346 slREDADDLEERAEELREEA-AELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVdlgNAEDFLEELREERdEL 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 732 KQRLLEEQAKLQQ-QMDLQKNHIFR----------------LTQGLQEALDRADLLKTERSDLEYQLENIQvlyshEKVK 794
Cdd:PRK02224 425 REREAELEATLRTaRERVEEAEALLeagkcpecgqpvegspHVETIEEDRERVEELEAELEDLEEEVEEVE-----ERLE 499
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 795 MEGTISQQTKLIDFLQAKMDQPAKK---KKVPLqyNELKLALEKEKARCAELEEALQKTRIELRSAREEA 861
Cdd:PRK02224 500 RAEDLVEAEDRIERLEERREDLEELiaeRRETI--EEKRERAEELRERAAELEAEAEEKREAAAEAEEEA 567
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
314-783 |
3.23e-07 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 55.13 E-value: 3.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 314 QIKKDLADKEsLENMMQRHEEE--AHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKlaansslftqrnmkaqeEM 391
Cdd:pfam05557 13 QLQNEKKQME-LEHKRARIELEkkASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALR-----------------EQ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 392 ISELRQQKFYLETQAGKLEAQnrklEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLE---LKRQLTELQLSLQE 468
Cdd:pfam05557 75 AELNRLKKKYLEALNKKLNEK----ESQLADAREVISCLKNELSELRRQIQRAELELQSTNSEleeLQERLDLLKAKASE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 469 RE---SQLTALQAARAALESQLR--QAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRnsctvitDLEEQLNQLTEDN 543
Cdd:pfam05557 151 AEqlrQNLEKQQSSLAEAEQRIKelEFEIQSQEQDSEIVKNSKSELARIPELEKELERLR-------EHNKHLNENIENK 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 544 AELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTM---EALKTTCTMLEEQVLDLEALNDELL 620
Cdd:pfam05557 224 LLLKEEVEDLKRKLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNLrspEDLSRRIEQLQQREIVLKEENSSLT 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 621 EKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRI---TESRQVVELAVKEHKAEiLALQQALKEQKLKA 697
Cdd:pfam05557 304 SSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVlllTKERDGYRAILESYDKE-LTMSNYSPQLLERI 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 698 ESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQ-----KNHIFRLTQGLQEALDRADLLKT 772
Cdd:pfam05557 383 EEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLAdpsysKEEVDSLRRKLETLELERQRLRE 462
|
490
....*....|.
gi 1039770412 773 ERSDLEYQLEN 783
Cdd:pfam05557 463 QKNELEMELER 473
|
|
| PH |
smart00233 |
Pleckstrin homology domain; Domain commonly found in eukaryotic signalling proteins. The ... |
1012-1131 |
3.23e-07 |
|
Pleckstrin homology domain; Domain commonly found in eukaryotic signalling proteins. The domain family possesses multiple functions including the abilities to bind inositol phosphates, and various proteins. PH domains have been found to possess inserted domains (such as in PLC gamma, syntrophins) and to be inserted within other domains. Mutations in Brutons tyrosine kinase (Btk) within its PH domain cause X-linked agammaglobulinaemia (XLA) in patients. Point mutations cluster into the positively charged end of the molecule around the predicted binding site for phosphatidylinositol lipids.
Pssm-ID: 214574 [Multi-domain] Cd Length: 102 Bit Score: 50.24 E-value: 3.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1012 LHLEGWMKVPRNNKRGqqGWDRKYIVLEGSKVLIYDNEAREAGQRPVEEFELClpdgDVSIhgavgaSELANTAKADVPY 1091
Cdd:smart00233 1 VIKEGWLYKKSGGGKK--SWKKRYFVLFNSTLLYYKSKKDKKSYKPKGSIDLS----GCTV------REAPDPDSSKKPH 68
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1039770412 1092 ILKMeshphtTCWPGRTLYLLAPSFPDKQRWVTALESVVA 1131
Cdd:smart00233 69 CFEI------KTSDRKTLLLQAESEEEREKWVEALRKAIA 102
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
204-585 |
4.81e-07 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 54.96 E-value: 4.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 204 RQAKERAERELEKLHNREDSSeGIKKKLVEAEERrhsLENKVKRLETMERRENRLKDDIQTKS-------------EQIQ 270
Cdd:PRK04863 276 RHANERRVHLEEALELRRELY-TSRRQLAAEQYR---LVEMARELAELNEAESDLEQDYQAASdhlnlvqtalrqqEKIE 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 271 QMADKILELEEK-------HREAQVSAQHLEVHLKQKEQHYEEkikvldnqIKKDLADKESLENMMQRHEEEAHEKGKIL 343
Cdd:PRK04863 352 RYQADLEELEERleeqnevVEEADEQQEENEARAEAAEEEVDE--------LKSQLADYQQALDVQQTRAIQYQQAVQAL 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 344 SEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQN-----RKLEE 418
Cdd:PRK04863 424 ERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEawdvaRELLR 503
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 419 QLEKISHQDhsdkSRLLELETRLREVSLEHEEQKlELKRQLTELQLSLQ---ERESQLTALQAARAALESQLRQAKTELE 495
Cdd:PRK04863 504 RLREQRHLA----EQLQQLRMRLSELEQRLRQQQ-RAERLLAEFCKRLGknlDDEDELEQLQEELEARLESLSESVSEAR 578
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 496 ETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVD 575
Cdd:PRK04863 579 ERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALD 658
|
410
....*....|
gi 1039770412 576 HLRREITERE 585
Cdd:PRK04863 659 EEIERLSQPG 668
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
416-812 |
5.02e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 54.74 E-value: 5.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 416 LEEQLEKISHQdhsdksrLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAAR-------AALESQLR 488
Cdd:pfam15921 76 IERVLEEYSHQ-------VKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRrresqsqEDLRNQLQ 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 489 QAKTELEETTAEAEEEIQALTAHRDEIQRKF----DALRNSCTVITDLEEQ--------------------------LNQ 538
Cdd:pfam15921 149 NTVHELEAAKCLKEDMLEDSNTQIEQLRKMMlsheGVLQEIRSILVDFEEAsgkkiyehdsmstmhfrslgsaiskiLRE 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 539 LTEDNAELNNQNFYLSKQLD--EASGANDEIVQLRSEVDHLRREITEREMQLT-------SQKQTMEALKTTCTMLEEQV 609
Cdd:pfam15921 229 LDTEISYLKGRIFPVEDQLEalKSESQNKIELLLQQHQDRIEQLISEHEVEITgltekasSARSQANSIQSQLEIIQEQA 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 610 LDLEALN-DELLEKERQWEAWRSVLGDEKSQFECRVRELQRML---DTE-KQSRARADQRITES----RQVVELAVKEHK 680
Cdd:pfam15921 309 RNQNSMYmRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLvlaNSElTEARTERDQFSQESgnldDQLQKLLADLHK 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 681 AEilaLQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQ-QKLETerELKQRLLEEQAKLQQQMdlqknhifRLTQG 759
Cdd:pfam15921 389 RE---KELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEvQRLEA--LLKAMKSECQGQMERQM--------AAIQG 455
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 1039770412 760 LQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAK 812
Cdd:pfam15921 456 KNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEK 508
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
51-829 |
5.05e-07 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 55.06 E-value: 5.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 51 YITECSSLKRSLEQAR----------------------MEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLM 108
Cdd:TIGR01612 922 YIKICENTKESIEKFHnkqnilkeilnknidtikesnlIEKSYKDKFDNTLIDKINELDKAFKDASLNDYEAKNNELIKY 1001
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 109 MNQLEEDLvSARRRSDLYESelresrlaAEEFKRKANECQHKLMKA-KDQGKPEVGEYSKLEKINAEQQLKIQELQEKLE 187
Cdd:TIGR01612 1002 FNDLKANL-GKNKENMLYHQ--------FDEKEKATNDIEQKIEDAnKNIPNIEIAIHTSIYNIIDEIEKEIGKNIELLN 1072
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 188 KAV--KASTEATellqNIRQAKERAereleKLHNREDSSEgikkklveaeerrhslENKVKRLETMerreNRLKDDIQTK 265
Cdd:TIGR01612 1073 KEIleEAEINIT----NFNEIKEKL-----KHYNFDDFGK----------------EENIKYADEI----NKIKDDIKNL 1123
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 266 SEQIQQmadKILELEEkhreaqvsaqhlevhLKQKEQHYEEKIKVLDNQIkKDLADK-------ESLENMMQRHEEEAHE 338
Cdd:TIGR01612 1124 DQKIDH---HIKALEE---------------IKKKSENYIDEIKAQINDL-EDVADKaisnddpEEIEKKIENIVTKIDK 1184
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 339 KGKILSEQKAMINAMdSKIR----SLEQ-RIVELSEANKLAA----------NSSLFTQRNMKAQEEMISELRQQKFYLE 403
Cdd:TIGR01612 1185 KKNIYDEIKKLLNEI-AEIEkdktSLEEvKGINLSYGKNLGKlflekideekKKSEHMIKAMEAYIEDLDEIKEKSPEIE 1263
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 404 TQAGKLEAQNRKLEeqLEKISHQDHSDKsrlleletrlREVSLEHEEQKLELKrqltELQLSLQERESQLTALQAARAAL 483
Cdd:TIGR01612 1264 NEMGIEMDIKAEME--TFNISHDDDKDH----------HIISKKHDENISDIR----EKSLKIIEDFSEESDINDIKKEL 1327
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 484 ESQLRQAKTELEEttaeaeeeiqaLTAHRDEIQRKFDALR--NSCTVITDLEEQLNQLTEDNAELNNQ---NFYLSKQLD 558
Cdd:TIGR01612 1328 QKNLLDAQKHNSD-----------INLYLNEIANIYNILKlnKIKKIIDEVKEYTKEIEENNKNIKDEldkSEKLIKKIK 1396
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 559 EASGANDEIVQLRS-----EVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLdLEALNDELLEKERQWeawrsVL 633
Cdd:TIGR01612 1397 DDINLEECKSKIEStlddkDIDECIKKIKELKNHILSEESNIDTYFKNADENNENVL-LLFKNIEMADNKSQH-----IL 1470
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 634 GDEK----SQFECRVRELQRMLDTEKQSRARADQRITESRQVVELaVKEHKAEILALQQALKEQKLK---AESLSDK--- 703
Cdd:TIGR01612 1471 KIKKdnatNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKEL-FEQYKKDVTELLNKYSALAIKnkfAKTKKDSeii 1549
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 704 LNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAK----------LQQQMDLQKNHIFRLTQGLQEALDradlLKTE 773
Cdd:TIGR01612 1550 IKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKndksnkaaidIQLSLENFENKFLKISDIKKKIND----CLKE 1625
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 774 RSDLEYQLENIQVLYSHEKVKMEGtiSQQTKLIDFLQAKMDQpakKKKVPLQYNEL 829
Cdd:TIGR01612 1626 TESIEKKISSFSIDSQDTELKENG--DNLNSLQEFLESLKDQ---KKNIEDKKKEL 1676
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
6-491 |
6.97e-07 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 54.46 E-value: 6.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 6 EAMMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQD-----------LATYITECSSLKRSL------------ 62
Cdd:pfam12128 296 DDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDAdietaaadqeqLPSWQSELENLEERLkaltgkhqdvta 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 63 --EQARMEVSQEDDKALQLLHD----IREQSRKLQEIKEQEYQAQVEEMRlmmNQLEEDLVSARRRSDLYESELRESRL- 135
Cdd:pfam12128 376 kyNRRRSKIKEQNNRDIAGIKDklakIREARDRQLAVAEDDLQALESELR---EQLEAGKLEFNEEEYRLKSRLGELKLr 452
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 136 -----AAEEFKRKANECQHKLMKAKdqgkpevgeySKLEKINAEQqlkiQELQEKLEKAVKASTEATELLQNIRQAKERA 210
Cdd:pfam12128 453 lnqatATPELLLQLENFDERIERAR----------EEQEAANAEV----ERLQSELRQARKRRDQASEALRQASRRLEER 518
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 211 ERELEKLHNR----------------EDSSEGIKKKLVEAEERR------------------HSLENKVKRL-------- 248
Cdd:pfam12128 519 QSALDELELQlfpqagtllhflrkeaPDWEQSIGKVISPELLHRtdldpevwdgsvggelnlYGVKLDLKRIdvpewaas 598
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 249 -ETMERRENRLKDDIQTKSEQIQ----QMADKILELEEKHREAQVSAQHL--------------EVHLKQKEQHYEEKIK 309
Cdd:pfam12128 599 eEELRERLDKAEEALQSAREKQAaaeeQLVQANGELEKASREETFARTALknarldlrrlfdekQSEKDKKNKALAERKD 678
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 310 VLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQK-----AMINAMDSKIRSLEQRIVELSEANKlAANSSLFTQ-- 382
Cdd:pfam12128 679 SANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKqaywqVVEGALDAQLALLKAAIAARRSGAK-AELKALETWyk 757
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 383 RNMKAQ---EEMISELRQQKFYLETqagKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQL 459
Cdd:pfam12128 758 RDLASLgvdPDVIAKLKREIRTLER---KIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLI 834
|
570 580 590
....*....|....*....|....*....|..
gi 1039770412 460 TELQLSLQERESQLTALQAARAALESQLRQAK 491
Cdd:pfam12128 835 ADTKLRRAKLEMERKASEKQQVRLSENLRGLR 866
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
320-545 |
9.48e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.84 E-value: 9.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 320 ADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLaansslfTQRNMKAQEEMISELRQQK 399
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRA-------LEQELAALEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 400 FYLETQAGKLEAQNRKLEEQLEKISHQDH-------SDKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQ 472
Cdd:COG4942 93 AELRAELEAQKEELAELLRALYRLGRQPPlalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039770412 473 LTALQAARAALESQlrqaKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAE 545
Cdd:COG4942 173 RAELEALLAELEEE----RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
177-326 |
9.65e-07 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 51.85 E-value: 9.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 177 LKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNRedsSEGIKKKLVEAEERRHSLENKVKRLET--MERR 254
Cdd:COG1579 10 LDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTE---LEDLEKEIKRLELEIEEVEARIKKYEEqlGNVR 86
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 255 ENR----LKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKESLE 326
Cdd:COG1579 87 NNKeyeaLQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELE 162
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
164-326 |
1.01e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 51.85 E-value: 1.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 164 EYSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEgikKKLVEAeerrhsleN 243
Cdd:COG1579 18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYE---EQLGNV--------R 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 244 KVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKE 323
Cdd:COG1579 87 NNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAERE 166
|
...
gi 1039770412 324 SLE 326
Cdd:COG1579 167 ELA 169
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
313-868 |
1.12e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.99 E-value: 1.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 313 NQIKKDLADKESLENMMQRHEEEAHEKGKILSEQK---AMINAMDSKiRSLEQRIVE----LSEANKLAANSSLFTQRnm 385
Cdd:PTZ00121 1082 DAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKaeeAKKKAEDAR-KAEEARKAEdarkAEEARKAEDAKRVEIAR-- 1158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 386 KAQEEMISELRQQKfyleTQAGKLEAQNRKLE----EQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQLTE 461
Cdd:PTZ00121 1159 KAEDARKAEEARKA----EDAKKAEAARKAEEvrkaEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEE 1234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 462 LQLSLQEresqltALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTE 541
Cdd:PTZ00121 1235 AKKDAEE------AKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAK 1308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 542 DNAELNNQNFYLSKQLDEASGANDEI------VQLRSEVDHLRREITEREMQLTSQKQTMEALKTtctmlEEQVLDLEAL 615
Cdd:PTZ00121 1309 KKAEEAKKADEAKKKAEEAKKKADAAkkkaeeAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK-----EEAKKKADAA 1383
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 616 NDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVK-----------------E 678
Cdd:PTZ00121 1384 KKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKadeakkkaeeakkaeeaK 1463
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 679 HKAEILALQQALK---EQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQM---DLQKNH 752
Cdd:PTZ00121 1464 KKAEEAKKADEAKkkaEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKkadEAKKAE 1543
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 753 IFRLTQGLQEALD--------RADLLKTERSDLEYQLENIQVLYSHEKVKMEGTI----------SQQTKLIDFLQAKMD 814
Cdd:PTZ00121 1544 EKKKADELKKAEElkkaeekkKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMklyeeekkmkAEEAKKAEEAKIKAE 1623
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 815 QPAKKKKVPLQYNELKLALEKEKARCAEL--EEALQKTRIELRSAREEAAHRKATD 868
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELkkAEEENKIKAAEEAKKAEEDKKKAEE 1679
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
331-759 |
1.41e-06 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 53.42 E-value: 1.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 331 RHEEEAHEK-GKILSEQKAMINAMDsKIRSLEQRIVELS-EANKLAANSSLFTQRNMKAQEE---MISELRQQKfYLETQ 405
Cdd:COG3096 275 RHANERRELsERALELRRELFGARR-QLAEEQYRLVEMArELEELSARESDLEQDYQAASDHlnlVQTALRQQE-KIERY 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 406 AGKLEAQNRKLEEQLEKISHQDhsdkSRLLELETRLREVSLEHEEqkleLKRQLTELQLSLQERESQLTALQAARAALEs 485
Cdd:COG3096 353 QEDLEELTERLEEQEEVVEEAA----EQLAEAEARLEAAEEEVDS----LKSQLADYQQALDVQQTRAIQYQQAVQALE- 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 486 qlrQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRnsctvitDLEEQLNqLTEDNAELNNQNFYLSKQLD---EASG 562
Cdd:COG3096 424 ---KARALCGLPDLTPENAEDYLAAFRAKEQQATEEVL-------ELEQKLS-VADAARRQFEKAYELVCKIAgevERSQ 492
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 563 ANDEIVQLRSE----------VDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEkerqWEAWRSV 632
Cdd:COG3096 493 AWQTARELLRRyrsqqalaqrLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAE----LEAQLEE 568
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 633 LGDEKSQFECRVRELQRmldTEKQSRARADqritesrqvvELAVKEhkAEILALQQALkeqklkaESLSDKLND-LEKKH 711
Cdd:COG3096 569 LEEQAAEAVEQRSELRQ---QLEQLRARIK----------ELAARA--PAWLAAQDAL-------ERLREQSGEaLADSQ 626
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1039770412 712 AMleMNARslQQKLETERELKQ---RLLEEQAKLQQQmdlqknhIFRLTQG 759
Cdd:COG3096 627 EV--TAAM--QQLLEREREATVerdELAARKQALESQ-------IERLSQP 666
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
450-701 |
1.75e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.07 E-value: 1.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 450 EQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTEleettaeaeeeIQALTAHRDEIQRKFDALRNSctvI 529
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR-----------IAALARRIRALEQELAALEAE---L 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 530 TDLEEQLNQLtedNAELNNQNFYLSKQLDEA--SGANDEIVQLRSevdhlRREITEREMQLTSQKQTMEALKTTCTMLEE 607
Cdd:COG4942 86 AELEKEIAEL---RAELEAQKEELAELLRALyrLGRQPPLALLLS-----PEDFLDAVRRLQYLKYLAPARREQAEELRA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 608 QVLDLEALNDELLEKERQWEAWRSVLGDEKsqfecrvRELQRMLDTEKQSRARADQRITESRQVVEL---AVKEHKAEIL 684
Cdd:COG4942 158 DLAELAALRAELEAERAELEALLAELEEER-------AALEALKAERQKLLARLEKELAELAAELAElqqEAEELEALIA 230
|
250
....*....|....*..
gi 1039770412 685 ALQQALKEQKLKAESLS 701
Cdd:COG4942 231 RLEAEAAAAAERTPAAG 247
|
|
| C1_1 |
pfam00130 |
Phorbol esters/diacylglycerol binding domain (C1 domain); This domain is also known as the ... |
926-981 |
1.91e-06 |
|
Phorbol esters/diacylglycerol binding domain (C1 domain); This domain is also known as the Protein kinase C conserved region 1 (C1) domain.
Pssm-ID: 395079 Cd Length: 53 Bit Score: 46.28 E-value: 1.91e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1039770412 926 HHNIPHRFNvglnmRATKCAVCLDTV-HFGRQASKCLECQVMCHPKCSTCLPATCGL 981
Cdd:pfam00130 1 HHFVHRNFK-----QPTFCDHCGEFLwGLGKQGLKCSWCKLNVHKRCHEKVPPECGC 52
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
148-455 |
2.58e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 52.43 E-value: 2.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 148 QHKLMKAKDQGKPEVGEYSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERaeRELEKLHNREDSSEGI 227
Cdd:pfam17380 298 QERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERK--RELERIRQEEIAMEIS 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 228 K-KKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVsaQHLEvhlkqkeqhyEE 306
Cdd:pfam17380 376 RmRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREV--RRLE----------EE 443
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 307 KIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMK 386
Cdd:pfam17380 444 RAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEME 523
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039770412 387 AQEEMISELRQQKFYLETQAGKLEAQNRK-LEEQLEKISHQdhsdKSRL--LELETRLREVSLEHEEQKLEL 455
Cdd:pfam17380 524 ERQKAIYEEERRREAEEERRKQQEMEERRrIQEQMRKATEE----RSRLeaMEREREMMRQIVESEKARAEY 591
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
506-741 |
3.03e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.30 E-value: 3.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 506 QALTAHRDEIQRKFDALRNSctvITDLEEQLNQLTEDNAELNNQNFYLSKQLDEA----SGANDEIVQLRSEVDHLRREI 581
Cdd:COG4942 16 AAQADAAAEAEAELEQLQQE---IAELEKELAALKKEEKALLKQLAALERRIAALarriRALEQELAALEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 582 TEREMQLTSQKQTM-EALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQfecrVRELQRMLDTEKQSRar 660
Cdd:COG4942 93 AELRAELEAQKEELaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQ----AEELRADLAELAALR-- 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 661 adQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLEterelkqRLLEEQA 740
Cdd:COG4942 167 --AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA-------RLEAEAA 237
|
.
gi 1039770412 741 K 741
Cdd:COG4942 238 A 238
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
96-302 |
3.37e-06 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 51.94 E-value: 3.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 96 QEYQAQVEEMRlmMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRkanecQHKLMKAKDQGKPEVGEYSKLEK--INA 173
Cdd:COG3206 159 EAYLEQNLELR--REEARKALEFLEEQLPELRKELEEAEAALEEFRQ-----KNGLVDLSEEAKLLLQQLSELESqlAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 174 EQQL-----KIQELQEKLEKAVKASTEATE--LLQNIRQAKERAERELEKLHNR--EDSSE--GIKKKLVEAEERRHSLE 242
Cdd:COG3206 232 RAELaeaeaRLAALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELSARytPNHPDviALRAQIAALRAQLQQEA 311
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039770412 243 NKVK-----RLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQ 302
Cdd:COG3206 312 QRILasleaELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEE 376
|
|
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
258-748 |
7.98e-06 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 50.95 E-value: 7.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 258 LKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKikvldNQikkDLADKESLEnmmqrheeEAH 337
Cdd:PRK10246 424 LRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEK-----TQ---QLADVKTIC--------EQE 487
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 338 EKGKILSEQKAMINAMDS--KIRSLEQRIVELSEANKLAANsslftQRNMKAQEEMISELRQQKFYLEtqaGKLEAqnrk 415
Cdd:PRK10246 488 ARIKDLEAQRAQLQAGQPcpLCGSTSHPAVEAYQALEPGVN-----QSRLDALEKEVKKLGEEGAALR---GQLDA---- 555
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 416 LEEQLekisHQDHSDKSRLLELETRLRE----------VSL-------------EHEEQKLELKRQLTELQLSLQERESQ 472
Cdd:PRK10246 556 LTKQL----QRDESEAQSLRQEEQALTQqwqavcaslnITLqpqddiqpwldaqEEHERQLRLLSQRHELQGQIAAHNQQ 631
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 473 LTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRkfdaLRNSCTVITDLEEQLNQLTEDNAELnnqnfy 552
Cdd:PRK10246 632 IIQYQQQIEQRQQQLLTALAGYALTLPQEDEEASWLATRQQEAQS----WQQRQNELTALQNRIQQLTPLLETL------ 701
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 553 lsKQLDEASgANDEIVQLrsevDHLrREITEREMQLTSQKQTMEALkttctmleeqvldlealndELLEKERQWEA---W 629
Cdd:PRK10246 702 --PQSDDLP-HSEETVAL----DNW-RQVHEQCLSLHSQLQTLQQQ-------------------DVLEAQRLQKAqaqF 754
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 630 RSVLgdEKSQFECRVRELQRMLDTEkqsrarADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEK 709
Cdd:PRK10246 755 DTAL--QASVFDDQQAFLAALLDEE------TLTQLEQLKQNLENQRQQAQTLVTQTAQALAQHQQHRPDGLDLTVTVEQ 826
|
490 500 510
....*....|....*....|....*....|....*....
gi 1039770412 710 KHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDL 748
Cdd:PRK10246 827 IQQELAQLAQQLRENTTRQGEIRQQLKQDADNRQQQQAL 865
|
|
| COG5281 |
COG5281 |
Phage-related minor tail protein [Mobilome: prophages, transposons]; |
340-767 |
9.57e-06 |
|
Phage-related minor tail protein [Mobilome: prophages, transposons];
Pssm-ID: 444092 [Multi-domain] Cd Length: 603 Bit Score: 50.38 E-value: 9.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 340 GKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQ 419
Cdd:COG5281 3 ALAAAAALAAAAAAAAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADALAA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 420 LEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQLTELQlslQERESQLTALQAARAALESQLRQAKTELEETTA 499
Cdd:COG5281 83 ALAEDAAAAAAAAEAALAALAAAALALAAAALAEAALAAAAAAA---AAAAAAAAAAAAAAAAAAEAAKAAAAAAAAAAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 500 EAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRR 579
Cdd:COG5281 160 AAAAAAAAAAAAAAAAAAALAAASAAAAAAAAKAAAEAAAEAAAAAEAAAAAAAAAAEAAAAEAQALAAAALAEQAALAA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 580 EITE--REMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQfecRVRELQRMLDTEKQS 657
Cdd:COG5281 240 ASAAaqALAALAAAAAAAALALAAAAELALTAQAEAAAAAAAAAAAAAQAAEAAAAAAEAQA---LAAAAAAAAAQLAAA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 658 RARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDlekkhAMLEMNARSLQQKLETERELKQRLLE 737
Cdd:COG5281 317 AAAAAQALRAAAQALAALAQRALAAAALAAAAQEAALAAAAAALQAALE-----AAAAAAAAELAAAGDWAAGAKAALAE 391
|
410 420 430
....*....|....*....|....*....|
gi 1039770412 738 EQAKLQQQMDLQKNHIFRLTQGLQEALDRA 767
Cdd:COG5281 392 YADSATNVAAQVAQAATSAFSGLTDALAGA 421
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
1488-1579 |
1.10e-05 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 50.46 E-value: 1.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1488 ESGTEQHRVPSTSRSSPNKRGPP--TYNEHITKR--------------VASSPAPPEGPSHPREPSTPHRYRDREGRTEL 1551
Cdd:PTZ00449 527 KEGEEGEHEDSKESDEPKEGGKPgeTKEGEVGKKpgpakehkpskiptLSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRP 606
|
90 100 110
....*....|....*....|....*....|
gi 1039770412 1552 RRDKSPGRP--LEREKSPGRMLSTRRERSP 1579
Cdd:PTZ00449 607 TRPKSPKLPelLDIPKSPKRPESPKSPKRP 636
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
15-364 |
1.16e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.15 E-value: 1.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 15 RLHRRVSEVEAVLSQKEV---ELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQ-LLHDIREQSRKL 90
Cdd:COG4717 129 PLYQELEALEAELAELPErleELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQdLAEELEELQQRL 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 91 QEIKEQEYQAQVEEMRLM--MNQLEEDLVSARRRSDLYE--------SELRESRLAAEEFKRKANE-------------- 146
Cdd:COG4717 209 AELEEELEEAQEELEELEeeLEQLENELEAAALEERLKEarlllliaAALLALLGLGGSLLSLILTiagvlflvlgllal 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 147 CQHKLMKAKDQGKPEVGEYSKLEKINAEQQLKIQELQEKLEKAVKAS-TEATELLQNIRQAK------ERAERELEKLHN 219
Cdd:COG4717 289 LFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSpEELLELLDRIEELQellreaEELEEELQLEEL 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 220 REDSSEGIKKKLVEAEErrhSLENKVKRLEtmerRENRLKDDIQTKSEQIQQMADKILELEEKHREAQvsaqhlevhLKQ 299
Cdd:COG4717 369 EQEIAALLAEAGVEDEE---ELRAALEQAE----EYQELKEELEELEEQLEELLGELEELLEALDEEE---------LEE 432
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039770412 300 KEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEahekgKILSEQKAMINAMDSKIRSLEQRI 364
Cdd:COG4717 433 ELEELEEELEELEEELEELREELAELEAELEQLEED-----GELAELLQELEELKAELRELAEEW 492
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
10-572 |
1.21e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 50.17 E-value: 1.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 10 EQEMTRLHRRVSEVEAVLsQKEVELKASETQRSLleqDLATYITECSSLKRSLEQaRMEVSQEDDKALQllhdireqsRK 89
Cdd:pfam01576 453 EGKNIKLSKDVSSLESQL-QDTQELLQEETRQKL---NLSTRLRQLEDERNSLQE-QLEEEEEAKRNVE---------RQ 518
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 90 LQEIKEQ--EYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKL---MKAKDQGKPEVGE 164
Cdd:pfam01576 519 LSTLQAQlsDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELddlLVDLDHQRQLVSN 598
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 165 YSKLEK----INAEQQLKIQELQEKLEKAVKASTEA-------TELLQNIRQAKERAER-------ELEKLHNREDSS-- 224
Cdd:pfam01576 599 LEKKQKkfdqMLAEEKAISARYAEERDRAEAEAREKetralslARALEEALEAKEELERtnkqlraEMEDLVSSKDDVgk 678
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 225 ----------------EGIKKKLVEAEERRHSLENKVKRLE-TMERRENRLKDDIQTKSEQ--------IQQMADKILEL 279
Cdd:pfam01576 679 nvhelerskraleqqvEEMKTQLEELEDELQATEDAKLRLEvNMQALKAQFERDLQARDEQgeekrrqlVKQVRELEAEL 758
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 280 EE--KHREAQVSA-QHLEVHLKQKEQHYEEKIKVLDNQIKKdLADKESLENMMQRHEEEAHekgkiLSEQKAMINAMDS- 355
Cdd:pfam01576 759 EDerKQRAQAVAAkKKLELDLKELEAQIDAANKGREEAVKQ-LKKLQAQMKDLQRELEEAR-----ASRDEILAQSKESe 832
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 356 -KIRSLEQRIVELSEanKLAANSSLFTQRNM---KAQEEMI------SELRQQKFYLETQAGKLEAQNRklEEQLEKISH 425
Cdd:pfam01576 833 kKLKNLEAELLQLQE--DLAASERARRQAQQerdELADEIAsgasgkSALQDEKRRLEARIAQLEEELE--EEQSNTELL 908
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 426 QDHSDKSRLL--ELETRL---REVSLEHEEQKLELKRQLTELQLSLQERESQ--------LTALQAARAALESQLRQ--- 489
Cdd:pfam01576 909 NDRLRKSTLQveQLTTELaaeRSTSQKSESARQQLERQNKELKAKLQEMEGTvkskfkssIAALEAKIAQLEEQLEQesr 988
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 490 -----AKTELEETTAEAEEEIQALTAHRDEIQRKfDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGAN 564
Cdd:pfam01576 989 erqaaNKLVRRTEKKLKEVLLQVEDERRHADQYK-DQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESN 1067
|
650
....*....|..
gi 1039770412 565 D----EIVQLRS 572
Cdd:pfam01576 1068 EsmnrEVSTLKS 1079
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
179-789 |
1.25e-05 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 50.46 E-value: 1.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 179 IQELQEKLEKavkasteatELLQNIRQAKERAERELEkLHNREDSSEGIKKKlVEAEERRHSLENKVKRLETMERRENRL 258
Cdd:COG5022 819 IIKLQKTIKR---------EKKLRETEEVEFSLKAEV-LIQKFGRSLKAKKR-FSLLKKETIYLQSAQRVELAERQLQEL 887
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 259 KDDIqtksEQIQQMADKILELEEKHREAQVSAQHLEV-HLKQKEQHYEEKIKVLDN-QIKKDLA-DKESLENMMQRHEEE 335
Cdd:COG5022 888 KIDV----KSISSLKLVNLELESEIIELKKSLSSDLIeNLEFKTELIARLKKLLNNiDLEEGPSiEYVKLPELNKLHEVE 963
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 336 A--HEKGKILSeqkAMINAMDSKIRSLEQRIVELSEANKLAAnsslftqrnmkaqeemisELRQQKFYLETQAGKLEAQN 413
Cdd:COG5022 964 SklKETSEEYE---DLLKKSTILVREGNKANSELKNFKKELA------------------ELSKQYGALQESTKQLKELP 1022
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 414 RKLEE--QLEKISHQDHSDKSRLLELEtrlrEVSLEHEEQKLELKRQLTELQLslqERESQLTalqaaraaLESQLRQAK 491
Cdd:COG5022 1023 VEVAElqSASKIISSESTELSILKPLQ----KLKGLLLLENNQLQARYKALKL---RRENSLL--------DDKQLYQLE 1087
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 492 TELEETTAEAEEEIQALTahrdeiqRKFDALRNSCTVITDLEEQLNqLTEDNAELNNQNFYLSKQLDEASGANDEIVQLR 571
Cdd:COG5022 1088 STENLLKTINVKDLEVTN-------RNLVKPANVLQFIVAQMIKLN-LLQEISKFLSQLVNTLEPVFQKLSVLQLELDGL 1159
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 572 SEVDHLRREITEREMQLTSQKQTME--ALKTTCTMLEEQVLDLEalnDELLEKERQ-WEAWRSVLGDEKSQFECRVRELQ 648
Cdd:COG5022 1160 FWEANLEALPSPPPFAALSEKRLYQsaLYDEKSKLSSSEVNDLK---NELIALFSKiFSGWPRGDKLKKLISEGWVPTEY 1236
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 649 RMLDTEKQSRAR--ADQRITESRQVVELAVKehkaeilaLQQALKEQKLKAESLSDKLNDLEKKHAM-----LEMNARSL 721
Cdd:COG5022 1237 STSLKGFNNLNKkfDTPASMSNEKLLSLLNS--------IDNLLSSYKLEEEVLPATINSLLQYINVglfnaLRTKASSL 1308
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770412 722 QQKLETERELKQRLLEEQAKLQQQMDLQKNhifrltqgLQEALDRADLLKTERSDLEYQLENIQVLYS 789
Cdd:COG5022 1309 RWKSATEVNYNSEELDDWCREFEISDVDEE--------LEELIQAVKVLQLLKDDLNKLDELLDACYS 1368
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
84-784 |
1.40e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 49.82 E-value: 1.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 84 REQSRKLQEIKEQEYQAQVE--EMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKLMKAKDQGKPE 161
Cdd:pfam10174 49 KEEAARISVLKEQYRVTQEEnqHLQLTIQALQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQ 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 162 VGEYSKLEKINAEQQLKIQELQEKLEkavkASTEATELLQNIRQAKERAERELEKLHNRedssegiKKKLVEAEERRHSL 241
Cdd:pfam10174 129 AKELFLLRKTLEEMELRIETQKQTLG----ARDESIKKLLEMLQSKGLPKKSGEEDWER-------TRRIAEAEMQLGHL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 242 ENKV--KRLETMERRE-----NRLKDDiQTKSEQIQQMAD----KILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKV 310
Cdd:pfam10174 198 EVLLdqKEKENIHLREelhrrNQLQPD-PAKTKALQTVIEmkdtKISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQ 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 311 LD-------------NQIKKDLADKESLENMMQRHEEEAHEKGkilSEQKAMINAMDSKIRSLEQRIVEL-SEANKLaan 376
Cdd:pfam10174 277 MEvykshskfmknkiDQLKQELSKKESELLALQTKLETLTNQN---SDCKQHIEVLKESLTAKEQRAAILqTEVDAL--- 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 377 sslftQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREvsleHEEQKLELK 456
Cdd:pfam10174 351 -----RLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRD----KDKQLAGLK 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 457 RQLTELQLSLQERESQLTALQAARAALEsqlrqakteleettaeaeEEIQALTAHRD-EIQRKFDALRNSCTVITDLEEQ 535
Cdd:pfam10174 422 ERVKSLQTDSSNTDTALTTLEEALSEKE------------------RIIERLKEQRErEDRERLEELESLKKENKDLKEK 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 536 LNQLtedNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREI---TEREMQLTSQKQTMEALKTTCTMLEEQVLDL 612
Cdd:pfam10174 484 VSAL---QPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVeqkKEECSKLENQLKKAHNAEEAVRTNPEINDRI 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 613 ealndELLEKERQWEAWRSvlgdEKSQFEC-RVRELQRMLDTEKQSRaraDQRITEsrqvvelavkehkAEILALQQaLK 691
Cdd:pfam10174 561 -----RLLEQEVARYKEES----GKAQAEVeRLLGILREVENEKNDK---DKKIAE-------------LESLTLRQ-MK 614
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 692 EQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQ--RLLEEQAKLQQQMDLQKNHIFRLTQGLQEaldRADL 769
Cdd:pfam10174 615 EQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQleELMGALEKTRQELDATKARLSSTQQSLAE---KDGH 691
|
730
....*....|....*
gi 1039770412 770 LKTERSDLEYQLENI 784
Cdd:pfam10174 692 LTNLRAERRKQLEEI 706
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
165-780 |
1.41e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 49.74 E-value: 1.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 165 YSKLEKINAEQQLKIQELQEKLEKAvkasteatELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSlenK 244
Cdd:pfam05557 6 ESKARLSQLQNEKKQMELEHKRARI--------ELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALRE---Q 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 245 VKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLkqKEQHYEekikvldnqikkdladkes 324
Cdd:pfam05557 75 AELNRLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELEL--QSTNSE------------------- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 325 LENMMQRHEEEaHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTqRNMKAQEEMISElrqqkfyLET 404
Cdd:pfam05557 134 LEELQERLDLL-KAKASEAEQLRQNLEKQQSSLAEAEQRIKELEFEIQSQEQDSEIV-KNSKSELARIPE-------LEK 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 405 QAGKLEAQNRKLEEQLEKIS---HQDHSDKSRLLELE-TRLREVSLEHEEQKLELKrqLTELQLSLQERESQLTALQAAR 480
Cdd:pfam05557 205 ELERLREHNKHLNENIENKLllkEEVEDLKRKLEREEkYREEAATLELEKEKLEQE--LQSWVKLAQDTGLNLRSPEDLS 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 481 AALEsQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSctvITDLEEQLNQLTEDNAELNNQNFYLSKQLDea 560
Cdd:pfam05557 283 RRIE-QLQQREIVLKEENSSLTSSARQLEKARRELEQELAQYLKK---IEDLNKKLKRHKALVRRLQRRVLLLTKERD-- 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 561 sgandeivqlrsevdhLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELlekerqweawrsvlgdeksqf 640
Cdd:pfam05557 357 ----------------GYRAILESYDKELTMSNYSPQLLERIEEAEDMTQKMQAHNEEM--------------------- 399
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 641 ECRVRELQRMLDTEKQSRARADQRITESRQVVELA-VKEHKAEILALQQALKEQKLKAESLSDKLNDLEkkhamLEMNAR 719
Cdd:pfam05557 400 EAQLSVAEEELGGYKQQAQTLERELQALRQQESLAdPSYSKEEVDSLRRKLETLELERQRLREQKNELE-----MELERR 474
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039770412 720 SLQQKLETER------------ELKQRLLEEQAKLQQQMDLQKnhifRLTQGLQEALDRADLLKTERSDLEYQ 780
Cdd:pfam05557 475 CLQGDYDPKKtkvlhlsmnpaaEAYQQRKNQLEKLQAEIERLK----RLLKKLEDDLEQVLRLPETTSTMNFK 543
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
197-542 |
1.58e-05 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 49.30 E-value: 1.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 197 TELLQNIRQAKERAErELEKLHNRE-DSSEGIKKKLVEAEERRHSLENKVKRLET-MERRENRLKDDIQTKSEQIQQMAD 274
Cdd:pfam19220 37 EAILRELPQAKSRLL-ELEALLAQErAAYGKLRRELAGLTRRLSAAEGELEELVArLAKLEAALREAEAAKEELRIELRD 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 275 KILELEEKHREAQVSAQHLEvHLKQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMD 354
Cdd:pfam19220 116 KTAQAEALERQLAAETEQNR-ALEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRLQALSEEQAAELAELT 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 355 SKIRSLEQRI------VELSEANKLAANSSlfTQRNMKAQEEMISELRQQKfylETQAGKLEAQNRKLE--EQLekishq 426
Cdd:pfam19220 195 RRLAELETQLdatrarLRALEGQLAAEQAE--RERAEAQLEEAVEAHRAER---ASLRMKLEALTARAAatEQL------ 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 427 dhsdksrLLELETRLRevslEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQ 506
Cdd:pfam19220 264 -------LAEARNQLR----DRDEAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQFQEMQRARAELEERAEMLTK 332
|
330 340 350
....*....|....*....|....*....|....*.
gi 1039770412 507 ALTAHRdeiqrkfDALRNSCTVITDLEEQLNQLTED 542
Cdd:pfam19220 333 ALAAKD-------AALERAEERIASLSDRIAELTKR 361
|
|
| Tropomyosin |
pfam00261 |
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ... |
141-336 |
1.72e-05 |
|
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.
Pssm-ID: 459736 [Multi-domain] Cd Length: 235 Bit Score: 48.10 E-value: 1.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 141 KRKANECQHKLMKAKDQGKPEVGEYSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNR 220
Cdd:pfam00261 7 KEELDEAEERLKEAMKKLEEAEKRAEKAEAEVAALNRRIQLLEEELERTEERLAEALEKLEEAEKAADESERGRKVLENR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 221 ----EDSSEGIKKKLVEAEERRHSLEnkvKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVH 296
Cdd:pfam00261 87 alkdEEKMEILEAQLKEAKEIAEEAD---RKYEEVARKLVVVEGDLERAEERAELAESKIVELEEELKVVGNNLKSLEAS 163
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1039770412 297 LK---QKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEA 336
Cdd:pfam00261 164 EEkasEREDKYEEQIRFLTEKLKEAETRAEFAERSVQKLEKEV 206
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
137-591 |
1.75e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 49.95 E-value: 1.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 137 AEEFKRKANECQHKLMKAKDQgkpEVGEYSKLEKINAEQQL---------KIQELQEKLEKAVKASTEATELLQNIRQAK 207
Cdd:COG3096 270 AADYMRHANERRELSERALEL---RRELFGARRQLAEEQYRlvemareleELSARESDLEQDYQAASDHLNLVQTALRQQ 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 208 ERAER------EL-EKLHNREDSSEGIKKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELE 280
Cdd:COG3096 347 EKIERyqedleELtERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKAR 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 281 EKHREAQVSAQHLEVHLKQkeqhYEEKIKVLDNQIKkDLADKESLENMMQRHEEEAHEK-GKILSEqkaminamdskirs 359
Cdd:COG3096 427 ALCGLPDLTPENAEDYLAA----FRAKEQQATEEVL-ELEQKLSVADAARRQFEKAYELvCKIAGE-------------- 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 360 leqriVELSEANKlAANSSLFTQRNMKAQEEMISELRQQKFYLEtqagKLEAQNRKLEEQLEKISHQDHSDKSRLLELEt 439
Cdd:COG3096 488 -----VERSQAWQ-TARELLRRYRSQQALAQRLQQLRAQLAELE----QRLRQQQNAERLLEEFCQRIGQQLDAAEELE- 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 440 rlrEVSLEHEEQKLELKRQLTELQlslqeresqltalqaaraALESQLRQakteleettaeaeeeiqaltaHRDEIQRKF 519
Cdd:COG3096 557 ---ELLAELEAQLEELEEQAAEAV------------------EQRSELRQ---------------------QLEQLRARI 594
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039770412 520 DALRNSCTVITDLEEQLNQLtednAELNNQNFYLSKQLDEASganDEIVQLRSEVDHLRREITEREMQLTSQ 591
Cdd:COG3096 595 KELAARAPAWLAAQDALERL----REQSGEALADSQEVTAAM---QQLLEREREATVERDELAARKQALESQ 659
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
367-599 |
1.94e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 49.24 E-value: 1.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 367 LSEANKLaaNSSLftqrnMKAQEEMISELRQQKFYLETQagkLEAQNRKLEEQlEKISHQDHSDKSrllELETRLREVSL 446
Cdd:PHA02562 165 LSEMDKL--NKDK-----IRELNQQIQTLDMKIDHIQQQ---IKTYNKNIEEQ-RKKNGENIARKQ---NKYDELVEEAK 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 447 EHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELE------------ETTAEAEEEIQALTAHRDE 514
Cdd:PHA02562 231 TIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKmyekggvcptctQQISEGPDRITKIKDKLKE 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 515 IQRKFDALRNSctvITDLEEQLNQ-------LTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQ 587
Cdd:PHA02562 311 LQHSLEKLDTA---IDELEEIMDEfneqskkLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDE 387
|
250
....*....|..
gi 1039770412 588 LTSQKQTMEALK 599
Cdd:PHA02562 388 LDKIVKTKSELV 399
|
|
| C1_SpBZZ1-like |
cd20824 |
protein kinase C conserved region 1 (C1 domain) found in Schizosaccharomyces pombe protein ... |
930-980 |
1.97e-05 |
|
protein kinase C conserved region 1 (C1 domain) found in Schizosaccharomyces pombe protein BZZ1 and similar proteins; BZZ1 is a syndapin-like F-BAR protein that plays a role in endocytosis and trafficking to the vacuole. It functions with type I myosins to restore polarity of the actin cytoskeleton after NaCl stress. BZZ1 contains an N-terminal F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs), a central coiled-coil, and two C-terminal SH3 domains. Schizosaccharomyces pombe BZZ1 also harbors a C1 domain, but Saccharomyces cerevisiae BZZ1 doesn't have any. This model corresponds to the C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410374 Cd Length: 53 Bit Score: 43.46 E-value: 1.97e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1039770412 930 PHRFNVGLNMRATKCAVCLDTV-HFGRQASKCLECQVMCHPKCSTCLPATCG 980
Cdd:cd20824 1 PHNFKPHSFSIPTKCDYCGEKIwGLSKKGLSCKDCGFNCHIKCELKVPPECP 52
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
346-549 |
2.00e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.99 E-value: 2.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 346 QKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISH 425
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 426 QDHSDKSRLLEL-------ETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETT 498
Cdd:COG4942 98 ELEAQKEELAELlralyrlGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1039770412 499 AEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQ 549
Cdd:COG4942 178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
204-648 |
2.04e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 49.57 E-value: 2.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 204 RQAKERAERELEKLHNREDSSeGIKKKLVEAEERrhsLENKVKRLETMERRENRLKDDIQTKS-------------EQIQ 270
Cdd:COG3096 275 RHANERRELSERALELRRELF-GARRQLAEEQYR---LVEMARELEELSARESDLEQDYQAASdhlnlvqtalrqqEKIE 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 271 QMADKILELEEKHREAQ-VSAQHLEVHLKQKEQ--HYEEKIKVLDNQikkdLADKESLENMMQRheeeahekgKILSEQK 347
Cdd:COG3096 351 RYQEDLEELTERLEEQEeVVEEAAEQLAEAEARleAAEEEVDSLKSQ----LADYQQALDVQQT---------RAIQYQQ 417
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 348 AminamdskIRSLEqRIVELSEANKLAANSSLFTQRNMKAQEEMISElrqqkfyletqagkleaqnrkleeqlekishqd 427
Cdd:COG3096 418 A--------VQALE-KARALCGLPDLTPENAEDYLAAFRAKEQQATE--------------------------------- 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 428 hsdksRLLELETRLReVSLEHEEQKlelkRQLTELQLSLQERESQLTALQAARAALEsQLRQAKTELEETtaeaeeeiQA 507
Cdd:COG3096 456 -----EVLELEQKLS-VADAARRQF----EKAYELVCKIAGEVERSQAWQTARELLR-RYRSQQALAQRL--------QQ 516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 508 LTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQ 587
Cdd:COG3096 517 LRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKE 596
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770412 588 LTSQK----QTMEALKTTCTMLEEQVLDLEALND---ELLEKERQWEAWRSVLGDEKSQFECRVRELQ 648
Cdd:COG3096 597 LAARApawlAAQDALERLREQSGEALADSQEVTAamqQLLEREREATVERDELAARKQALESQIERLS 664
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
10-780 |
2.34e-05 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 49.31 E-value: 2.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 10 EQEMTRLHRRVSEVEAVLSQ---KEVELKASETQRSLLEQDLATyitECSSLKRSL---EQARMEVSQEDDKALQLLHDI 83
Cdd:COG5022 799 LQPLLSLLGSRKEYRSYLACiikLQKTIKREKKLRETEEVEFSL---KAEVLIQKFgrsLKAKKRFSLLKKETIYLQSAQ 875
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 84 REQS--RKLQEIKEQEyqAQVEEMRLMMNQLEEDLVsaRRRSDLYESELRESRLAAEEFKRKanECQHKLMKAKDQGKPE 161
Cdd:COG5022 876 RVELaeRQLQELKIDV--KSISSLKLVNLELESEII--ELKKSLSSDLIENLEFKTELIARL--KKLLNNIDLEEGPSIE 949
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 162 VGEYSKLEKINaEQQLKIQELQEKLEKAVKASTEatellqnirqakeraerELEKLHNREDSSEGIKKKLVEAEERRHSL 241
Cdd:COG5022 950 YVKLPELNKLH-EVESKLKETSEEYEDLLKKSTI-----------------LVREGNKANSELKNFKKELAELSKQYGAL 1011
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 242 ENKVKRLETMERRENRLKDDIQTKSEqiqqmadkilELEEKHREAQVsaQHLEVHLKQKEQHYEEKIKVLDNQIkkdlad 321
Cdd:COG5022 1012 QESTKQLKELPVEVAELQSASKIISS----------ESTELSILKPL--QKLKGLLLLENNQLQARYKALKLRR------ 1073
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 322 keslenmmqrheeeahEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANklAANSSLFTQRNMKAqeemiselrQQKFY 401
Cdd:COG5022 1074 ----------------ENSLLDDKQLYQLESTENLLKTINVKDLEVTNRN--LVKPANVLQFIVAQ---------MIKLN 1126
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 402 LETQAGKLEAQNRKLEEQLEKishqdhSDKSRLLELETRLREVSLEHEEQKLELKRQltelqlsLQERESQLTALQAARA 481
Cdd:COG5022 1127 LLQEISKFLSQLVNTLEPVFQ------KLSVLQLELDGLFWEANLEALPSPPPFAAL-------SEKRLYQSALYDEKSK 1193
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 482 ALESQLRQAKTELeettaeaeeeiqaltahrDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEAS 561
Cdd:COG5022 1194 LSSSEVNDLKNEL------------------IALFSKIFSGWPRGDKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPAS 1255
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 562 GANDEIVQLRSEVDHLR----REITEREMQLTSQKQTM-----EALKTTCTMLEEQVLDLEALNDELLEkerQWeawrsv 632
Cdd:COG5022 1256 MSNEKLLSLLNSIDNLLssykLEEEVLPATINSLLQYInvglfNALRTKASSLRWKSATEVNYNSEELD---DW------ 1326
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 633 lgdeksqfeCRVRELQRmLDTEKQSraradqrITESRQVVELAVK--EHKAEILALQQALKE---QKLKAE-SLSDKLND 706
Cdd:COG5022 1327 ---------CREFEISD-VDEELEE-------LIQAVKVLQLLKDdlNKLDELLDACYSLNPaeiQNLKSRyDPADKENN 1389
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770412 707 LEKKHaMLEMNARSLQQKLETERELKQRLleeQAKLQQQMDLQKNHIFRLTQGLQ--EALDR--ADLLKTERSDLEYQ 780
Cdd:COG5022 1390 LPKEI-LKKIEALLIKQELQLSLEGKDET---EVHLSEIFSEEKSLISLDRNSIYkeEVLSSlsALLTKEKIALLDRK 1463
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
58-317 |
2.62e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 47.98 E-value: 2.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 58 LKRSLEQARMEVSQEDDKalqlLHDIREQSRKLQEiKEQEYQAQVEEMRLMMNQLEEdlvsarRRSDLYEsELRESRLAA 137
Cdd:COG1340 13 LEEKIEELREEIEELKEK----RDELNEELKELAE-KRDELNAQVKELREEAQELRE------KRDELNE-KVKELKEER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 138 EEFKRKANECQHKLMKAKDQGKPEVG----------EYSKLEK--------INAEQQL--KIQELQEKLE---KAVKAST 194
Cdd:COG1340 81 DELNEKLNELREELDELRKELAELNKaggsidklrkEIERLEWrqqtevlsPEEEKELveKIKELEKELEkakKALEKNE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 195 EATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSLenkVKRLETMERRENRLKDDIQTKSEQIQQMAD 274
Cdd:COG1340 161 KLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADEL---RKEADELHKEIVEAQEKADELHEEIIELQK 237
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1039770412 275 KILELEEKHREAQVSAQHLEVHLKQKEqhYEEKIKVLDNQIKK 317
Cdd:COG1340 238 ELRELRKELKKLRKKQRALKREKEKEE--LEEKAEEIFEKLKK 278
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
644-883 |
2.75e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.14 E-value: 2.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 644 VRELqrMLDtEKQSRARAD------QRITESRQVVELAVKEHKA--EILALQQALKEQKLKAESLSDKLNDLEKKHAMLE 715
Cdd:COG4913 213 VREY--MLE-EPDTFEAADalvehfDDLERAHEALEDAREQIELlePIRELAERYAAARERLAELEYLRAALRLWFAQRR 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 716 MNArsLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEA-LDRADLLKTERSDLEYQLENIqvlyshekvk 794
Cdd:COG4913 290 LEL--LEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEER---------- 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 795 mEGTISQQTKLIDFLQAKMDQPAKK-KKVPLQYNELKLALEKEKARC----AELEEALQKTRIELRSAREEAAHRKATDH 869
Cdd:COG4913 358 -ERRRARLEALLAALGLPLPASAEEfAALRAEAAALLEALEEELEALeealAEAEAALRDLRRELRELEAEIASLERRKS 436
|
250
....*....|....
gi 1039770412 870 PHPSTPATARQQIA 883
Cdd:COG4913 437 NIPARLLALRDALA 450
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
439-856 |
2.81e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 49.02 E-value: 2.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 439 TRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLrQAKTELEETTAEAEEEIQALTAHRDEIQRK 518
Cdd:pfam01576 1 TRQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQL-QAETELCAEAEEMRARLAARKQELEEILHE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 519 FDALrnsctvITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGA------------------NDEIVQLRSEVDHLRRE 580
Cdd:pfam01576 80 LESR------LEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAArqklqlekvtteakikklEEDILLLEDQNSKLSKE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 581 -------ITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEalnDELLEKERQW---EAWRSVLGDEKSQFECRVRELQRM 650
Cdd:pfam01576 154 rklleerISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLE---ERLKKEEKGRqelEKAKRKLEGESTDLQEQIAELQAQ 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 651 LDTEKQSRARADQRI----------TESRQVVELAVKEHKAEILALQQALKEQKL---KAESLSDKLN-DLEKKHAMLE- 715
Cdd:pfam01576 231 IAELRAQLAKKEEELqaalarleeeTAQKNNALKKIRELEAQISELQEDLESERAarnKAEKQRRDLGeELEALKTELEd 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 716 -MNARSLQQKLETERE-----LKQRLLEEQAKLQQQM-DLQKNHifrlTQGLQEALDRADLLKTERSDLEyqlENIQVLY 788
Cdd:pfam01576 311 tLDTTAAQQELRSKREqevteLKKALEEETRSHEAQLqEMRQKH----TQALEELTEQLEQAKRNKANLE---KAKQALE 383
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770412 789 SHEKvkmegtiSQQTKLIDFLQAKMDQPAKKKKVPLQYNELKLAL-EKEKARcAELEEALQKTRIELRS 856
Cdd:pfam01576 384 SENA-------ELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLsESERQR-AELAEKLSKLQSELES 444
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
169-848 |
2.89e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 48.89 E-value: 2.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 169 EKINAEQQLKIQELQEKLEKAVKASTEATEL-LQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSLENKVKR 247
Cdd:TIGR00606 177 EIFSATRYIKALETLRQVRQTQGQKVQEHQMeLKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 248 LETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAqvsAQHLEVHLKQKEQHYEEKIKvldnQIKKDLAD-KESLE 326
Cdd:TIGR00606 257 IEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKV---FQGTDEQLNDLYHNHQRTVR----EKERELVDcQRELE 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 327 NMMQRHEEEAHEKGKILSEQKAM----------INAMDSKIRSLEQR-----------------------IVELSEANKL 373
Cdd:TIGR00606 330 KLNKERRLLNQEKTELLVEQGRLqlqadrhqehIRARDSLIQSLATRleldgfergpfserqiknfhtlvIERQEDEAKT 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 374 AANSSLFTQRNMKAQEEMISELRQQKFYLetqAGKLEAQNRKLEEQLEKISH------QDHSDKSRLLELETRL----RE 443
Cdd:TIGR00606 410 AAQLCADLQSKERLKQEQADEIRDEKKGL---GRTIELKKEILEKKQEELKFvikelqQLEGSSDRILELDQELrkaeRE 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 444 VSLEHEEQKLE-LKRQLTELQL----------SLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAH- 511
Cdd:TIGR00606 487 LSKAEKNSLTEtLKKEVKSLQNekadldrklrKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLl 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 512 ----------------RDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVD 575
Cdd:TIGR00606 567 gyfpnkkqledwlhskSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKE 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 576 HLRREITEREM-------------QLT---------------SQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWE 627
Cdd:TIGR00606 647 EIEKSSKQRAMlagatavysqfitQLTdenqsccpvcqrvfqTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRD 726
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 628 AWRSVLGDEKSQFECRVRELQRMLD-TEKQSRARADQRITESRQVVELAV---KEHKAEIL--------ALQQALKEQKL 695
Cdd:TIGR00606 727 EMLGLAPGRQSIIDLKEKEIPELRNkLQKVNRDIQRLKNDIEEQETLLGTimpEEESAKVCltdvtimeRFQMELKDVER 806
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 696 KAESLSDKLN--DLEKKHAMLEMNARSLQQKLET---ERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLL 770
Cdd:TIGR00606 807 KIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDTvvsKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQF 886
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 771 KTErsdLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKK----KKVPLQYNELKLALEKEKARCAELEEA 846
Cdd:TIGR00606 887 EEQ---LVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKetsnKKAQDKVNDIKEKVKNIHGYMKDIENK 963
|
..
gi 1039770412 847 LQ 848
Cdd:TIGR00606 964 IQ 965
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
489-758 |
3.28e-05 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 47.88 E-value: 3.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 489 QAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSctvITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGAND--- 565
Cdd:pfam15905 66 QKNLKESKDQKELEKEIRALVQERGEQDKRLQALEEE---LEKVEAKLNAAVREKTSLSASVASLEKQLLELTRVNEllk 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 566 -----------------EIVQLRSEVDHLRREITER----EMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDElleker 624
Cdd:pfam15905 143 akfsedgtqkkmsslsmELMKLRNKLEAKMKEVMAKqegmEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIE------ 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 625 qweawrsvlgdEKSQFECRVRELQRMldteKQSRARADQRITESRQVVELAvKEHKAEILALQQALKEqklKAESLSDKL 704
Cdd:pfam15905 217 -----------EKSETEKLLEYITEL----SCVSEQVEKYKLDIAQLEELL-KEKNDEIESLKQSLEE---KEQELSKQI 277
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1039770412 705 NDLEKKHAMLEmnaRSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQ 758
Cdd:pfam15905 278 KDLNEKCKLLE---SEKEELLREYEEKEQTLNAELEELKEKLTLEEQEHQKLQQ 328
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
12-472 |
3.28e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 48.58 E-value: 3.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 12 EMTRLHRRVSEVEAVLSQKEV---------ELKASETQRSLLE-----QDLATYIT---ECSSLKRSLEQARMEVSQEDD 74
Cdd:pfam05557 3 ELIESKARLSQLQNEKKQMELehkrarielEKKASALKRQLDResdrnQELQKRIRlleKREAEAEEALREQAELNRLKK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 75 KALQLLHD-IREQSRKLQEIKE---------QEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESrlaaeEFKRKA 144
Cdd:pfam05557 83 KYLEALNKkLNEKESQLADAREvisclknelSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEA-----EQLRQN 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 145 NECQHKLMKAKDQGKPEVGEYSKLEKINAEQQLKIQELQE---KLEKAVKASTEATELLQNIRQAKERAERELEKLHNRE 221
Cdd:pfam05557 158 LEKQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELAripELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 222 DSSEGIKKKLVEAEERRHSLENKVK---RLETMERRENRLKDDIQTKSEQIQQmadkilelEEKHREAQVSAqhlevhLK 298
Cdd:pfam05557 238 EREEKYREEAATLELEKEKLEQELQswvKLAQDTGLNLRSPEDLSRRIEQLQQ--------REIVLKEENSS------LT 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 299 QKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEkgkiLSEQKAMInamdSKIRSLEQRIVELSEANKLAANSS 378
Cdd:pfam05557 304 SSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRR----LQRRVLLL----TKERDGYRAILESYDKELTMSNYS 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 379 LFTQRNMKAQEEMI-------SELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQ-DHSDKSRLLELETRLREVSLEHEE 450
Cdd:pfam05557 376 PQLLERIEEAEDMTqkmqahnEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQeSLADPSYSKEEVDSLRRKLETLEL 455
|
490 500
....*....|....*....|..
gi 1039770412 451 QKLELKRQLTELQLSLQERESQ 472
Cdd:pfam05557 456 ERQRLREQKNELEMELERRCLQ 477
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
297-490 |
3.42e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.90 E-value: 3.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 297 LKQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINA----MDSKIRSLEQRIVELSEANK 372
Cdd:COG3883 28 LQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEErreeLGERARALYRSGGSVSYLDV 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 373 LAANSSL--FTQRN------MKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEkishqdhsdksrllELETRLREV 444
Cdd:COG3883 108 LLGSESFsdFLDRLsalskiADADADLLEELKADKAELEAKKAELEAKLAELEALKA--------------ELEAAKAEL 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1039770412 445 slehEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQA 490
Cdd:COG3883 174 ----EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
166-521 |
3.47e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 47.97 E-value: 3.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 166 SKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNredssegikkklvEAEERRHSLENKV 245
Cdd:COG4372 27 AALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEE-------------ELEELNEQLQAAQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 246 KRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEqhyeEKIKVLDNQIKKDLADKESL 325
Cdd:COG4372 94 AELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAERE----EELKELEEQLESLQEELAAL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 326 ENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQ 405
Cdd:COG4372 170 EQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKE 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 406 AGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALES 485
Cdd:COG4372 250 ELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLE 329
|
330 340 350
....*....|....*....|....*....|....*.
gi 1039770412 486 QLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDA 521
Cdd:COG4372 330 LALAILLAELADLLQLLLVGLLDNDVLELLSKGAEA 365
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
286-510 |
3.70e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.90 E-value: 3.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 286 AQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIV 365
Cdd:COG3883 3 ALALAAPTPAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 366 ELSEA-NKLAA----NSSLFTQRNMKAQEEMISELRQQKFYLETQAgklEAQNRKLEEQLEkishqdhsDKSRLLELETR 440
Cdd:COG3883 83 ERREElGERARalyrSGGSVSYLDVLLGSESFSDFLDRLSALSKIA---DADADLLEELKA--------DKAELEAKKAE 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 441 LREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTA 510
Cdd:COG3883 152 LEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
131-591 |
4.06e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 48.20 E-value: 4.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 131 RESRLAAEEFKRKANECQHKLMKAKDQGKPEVGEYSKLEKINAEQQLKIQElQEKLEKAVKASTEATELLQNIRQAKERA 210
Cdd:pfam05557 23 LEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALRE-QAELNRLKKKYLEALNKKLNEKESQLAD 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 211 ERELEKLHNREDSsegikkklveaeERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSA 290
Cdd:pfam05557 102 AREVISCLKNELS------------ELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEAE 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 291 QHLEvHLKQKEQHYEEKIKVLDNqIKKDLADKESLENMMQRH-----------------EEEAHE-KGKILSEQKAMINA 352
Cdd:pfam05557 170 QRIK-ELEFEIQSQEQDSEIVKN-SKSELARIPELEKELERLrehnkhlnenienklllKEEVEDlKRKLEREEKYREEA 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 353 MDSKIRsLEQRIVELSEANKLAANSSLfTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKS 432
Cdd:pfam05557 248 ATLELE-KEKLEQELQSWVKLAQDTGL-NLRSPEDLSRRIEQLQQREIVLKEENSSLTSSARQLEKARRELEQELAQYLK 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 433 RLLELETRLRevslEHEEQKLELKRQLTelqLSLQEREsqltalqAARAALES-----QLRQAKTELEETTAEAEEEIQA 507
Cdd:pfam05557 326 KIEDLNKKLK----RHKALVRRLQRRVL---LLTKERD-------GYRAILESydkelTMSNYSPQLLERIEEAEDMTQK 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 508 LTAHRDEIQRKFDALRNSCTVITD----LEEQLNQLTEDnaELNNQNFYLSKQLDEASGANDEivqLRSEVDHLRREITE 583
Cdd:pfam05557 392 MQAHNEEMEAQLSVAEEELGGYKQqaqtLERELQALRQQ--ESLADPSYSKEEVDSLRRKLET---LELERQRLREQKNE 466
|
....*...
gi 1039770412 584 REMQLTSQ 591
Cdd:pfam05557 467 LEMELERR 474
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
558-747 |
4.68e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.52 E-value: 4.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 558 DEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQvldLEALNDELLEKERQWEAWRSVLGDek 637
Cdd:COG3883 16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAE---IDKLQAEIAEAEAEIEERREELGE-- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 638 sqfecRVRELQR------MLDTEKQSRARAD--QRITESRQVVElavkeHKAEILALQQALKEQ-KLKAESLSDKLNDLE 708
Cdd:COG3883 91 -----RARALYRsggsvsYLDVLLGSESFSDflDRLSALSKIAD-----ADADLLEELKADKAElEAKKAELEAKLAELE 160
|
170 180 190
....*....|....*....|....*....|....*....
gi 1039770412 709 KKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMD 747
Cdd:COG3883 161 ALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLA 199
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
388-728 |
5.41e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 47.81 E-value: 5.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 388 QEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELEtRLREVSLEHEEQKLELKRQLTELQlsLQ 467
Cdd:pfam17380 280 HQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMD-RQAAIYAEQERMAMERERELERIR--QE 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 468 ERESQLTALQAARAALE-SQLRQAKTELEETTAEAEEEIQALTAHR------DEIQRKfdalrnsctvitdLEEQLNQLT 540
Cdd:pfam17380 357 ERKRELERIRQEEIAMEiSRMRELERLQMERQQKNERVRQELEAARkvkileEERQRK-------------IQQQKVEME 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 541 EDNAELNNQNFYLSKQLDEasgandeivQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLD---LEALND 617
Cdd:pfam17380 424 QIRAEQEEARQREVRRLEE---------ERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDrkrAEEQRR 494
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 618 ELLEKErqWEAWRSVLGDEKSQfecrvrelQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEilaLQQALKEQKLKA 697
Cdd:pfam17380 495 KILEKE--LEERKQAMIEEERK--------RKLLEKEMEERQKAIYEEERRREAEEERRKQQEME---ERRRIQEQMRKA 561
|
330 340 350
....*....|....*....|....*....|.
gi 1039770412 698 ESLSDKLNDLEKKHAMLEMNARSLQQKLETE 728
Cdd:pfam17380 562 TEERSRLEAMEREREMMRQIVESEKARAEYE 592
|
|
| C1_CeDKF1-like_rpt2 |
cd20798 |
second protein kinase C conserved region 1 (C1 domain) found in Caenorhabditis elegans serine ... |
930-981 |
5.79e-05 |
|
second protein kinase C conserved region 1 (C1 domain) found in Caenorhabditis elegans serine/threonine-protein kinase DKF-1 and similar proteins; DKF-1 converts transient diacylglycerol (DAG) signals into prolonged physiological effects, independently of PKC. It plays a role in the regulation of growth and neuromuscular control of movement. It is involved in immune response to Staphylococcus aureus bacterium by activating transcription factor hlh-30 downstream of phospholipase plc-1. Members of this group contain two copies of the C1 domain. This model corresponds to the second one. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410348 Cd Length: 54 Bit Score: 42.10 E-value: 5.79e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1039770412 930 PHRFNVGLNMRATKCAVClDTVHFG--RQASKCLECQVMCHPKCSTCLPATCGL 981
Cdd:cd20798 1 PHTLAEHNYKKPTVCKVC-DKLLVGlvRQGLKCRDCGVNVHKKCASLLPSNCRL 53
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
241-422 |
6.13e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.13 E-value: 6.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 241 LENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIK---- 316
Cdd:COG3883 18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARalyr 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 317 -----------------KDLADKESLENMMQRHEeeahekGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSL 379
Cdd:COG3883 98 sggsvsyldvllgsesfSDFLDRLSALSKIADAD------ADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKA 171
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1039770412 380 FTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEK 422
Cdd:COG3883 172 ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAA 214
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
441-758 |
6.18e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 47.98 E-value: 6.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 441 LREVSLEHEEQKLeLKRQLTELQLSLQERESQ---LTALQAARAALESQLRQAKTEleettaeaeeeIQALTAHRDEIQR 517
Cdd:PRK11281 48 LNKQKLLEAEDKL-VQQDLEQTLALLDKIDRQkeeTEQLKQQLAQAPAKLRQAQAE-----------LEALKDDNDEETR 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 518 KfdalRNSCTVITDLEEQLNQLTEDNAELNNqnfylskqldEASGANDEIVQLRSEVDHLRREITE---REMQLTSQKQT 594
Cdd:PRK11281 116 E----TLSTLSLRQLESRLAQTLDQLQNAQN----------DLAEYNSQLVSLQTQPERAQAALYAnsqRLQQIRNLLKG 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 595 MEALKTTCTMLEEQVLDLE-ALNDELLEKERQWEAWRSVLGDeksqfecrVRELQRMLDTEKQsrARADQRITESRQVV- 672
Cdd:PRK11281 182 GKVGGKALRPSQRVLLQAEqALLNAQNDLQRKSLEGNTQLQD--------LLQKQRDYLTARI--QRLEHQLQLLQEAIn 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 673 --ELAVKEHKAEilALQQALKEQKLKAESLsdklndlekkhamlemnarsLQQKLETERELKQRLLEEQAKLQQ--QMDL 748
Cdd:PRK11281 252 skRLTLSEKTVQ--EAQSQDEAARIQANPL--------------------VAQELEINLQLSQRLLKATEKLNTltQQNL 309
|
330
....*....|.
gi 1039770412 749 Q-KNHIFRLTQ 758
Cdd:PRK11281 310 RvKNWLDRLTQ 320
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
346-635 |
6.73e-05 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 47.74 E-value: 6.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 346 QKAMINAMDSKIRSLEQRIVELSEANKLaansslftQRNMKAQEEMISELRQQKFYLETQAGKLEAQ--NRKLEEQLEKI 423
Cdd:PRK10929 43 QAEIVEALQSALNWLEERKGSLERAKQY--------QQVIDNFPKLSAELRQQLNNERDEPRSVPPNmsTDALEQEILQV 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 424 SHQdHSDKSRLLELET-RLREVS---LEHEEQKLELKRQLTELQLSLQERESQLTAL-QAARAAL--ESQLRQAKTELEE 496
Cdd:PRK10929 115 SSQ-LLEKSRQAQQEQdRAREISdslSQLPQQQTEARRQLNEIERRLQTLGTPNTPLaQAQLTALqaESAALKALVDELE 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 497 TTAEAEEEIQALTAHRDEI-QRKFDALRNSctvITDLEEQLNQLTEDNAElnnQNFYLSKQLDEASG--ANDEIVQLRse 573
Cdd:PRK10929 194 LAQLSANNRQELARLRSELaKKRSQQLDAY---LQALRNQLNSQRQREAE---RALESTELLAEQSGdlPKSIVAQFK-- 265
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039770412 574 vdhLRREITereMQLTSQKQTMEALKTTCTMLEEQVLDL-EALNDelLEKERQWEAWRSVLGD 635
Cdd:PRK10929 266 ---INRELS---QALNQQAQRMDLIASQQRQAASQTLQVrQALNT--LREQSQWLGVSNALGE 320
|
|
| PH_ROCK |
cd01242 |
Rho-associated coiled-coil containing protein kinase pleckstrin homology (PH) domain; ROCK is ... |
1013-1058 |
6.83e-05 |
|
Rho-associated coiled-coil containing protein kinase pleckstrin homology (PH) domain; ROCK is a serine/threonine kinase that binds GTP-Rho. It consists of a kinase domain, a coiled coil region and a PH domain. The ROCK PH domain is interrupted by a C1 domain. ROCK plays a role in cellular functions, such as contraction, adhesion, migration, and proliferation and in the regulation of apoptosis. There are two ROCK isoforms, ROCK1 and ROCK2. In ROCK2 the Rho Binding Domain (RBD) and the PH domain work together in membrane localization with RBD receiving the RhoA signal and the PH domain receiving the phospholipid signal. PH domains have diverse functions, but in general are involved in targeting proteins to the appropriate cellular location or in the interaction with a binding partner. They share little sequence conservation, but all have a common fold, which is electrostatically polarized. Less than 10% of PH domains bind phosphoinositide phosphates (PIPs) with high affinity and specificity. PH domains are distinguished from other PIP-binding domains by their specific high-affinity binding to PIPs with two vicinal phosphate groups: PtdIns(3,4)P2, PtdIns(4,5)P2 or PtdIns(3,4,5)P3 which results in targeting some PH domain proteins to the plasma membrane. A few display strong specificity in lipid binding. Any specificity is usually determined by loop regions or insertions in the N-terminus of the domain, which are not conserved across all PH domains. PH domains are found in cellular signaling proteins such as serine/threonine kinase, tyrosine kinases, regulators of G-proteins, endocytotic GTPases, adaptors, as well as cytoskeletal associated molecules and in lipid associated enzymes.
Pssm-ID: 269948 Cd Length: 110 Bit Score: 43.50 E-value: 6.83e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1039770412 1013 HLEGWMKVPRNNKRGQQGWDRKYIVLEGSKVLIYDNEAREAGQRPV 1058
Cdd:cd01242 2 RLEGWLSLPNKQNIRRHGWKKQYVVVSSKKILFYNSEQDKANSNPI 47
|
|
| C1_aPKC |
cd20794 |
protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) ... |
932-980 |
7.55e-05 |
|
protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) family; PKCs are classified into three groups (classical, atypical, and novel) depending on their mode of activation and the structural characteristics of their regulatory domain. aPKCs only require phosphatidylserine (PS) for activation. They contain a C2-like region, instead of a calcium-binding (C2) region found in classical PKCs, in their regulatory domain. There are two aPKC isoforms, zeta and iota. aPKCs are involved in many cellular functions including proliferation, migration, apoptosis, polarity maintenance and cytoskeletal regulation. They also play a critical role in the regulation of glucose metabolism and in the pathogenesis of type 2 diabetes. PKC-zeta plays a critical role in activating the glucose transport response. It is activated by glucose, insulin, and exercise through diverse pathways. PKC-zeta also plays a central role in maintaining cell polarity in yeast and mammalian cells. In addition, it affects actin remodeling in muscle cells. PKC-iota is directly implicated in carcinogenesis. It is critical to oncogenic signaling mediated by Ras and Bcr-Abl. The PKC-iota gene is the target of tumor-specific gene amplification in many human cancers, and has been identified as a human oncogene. In addition to its role in transformed growth, PKC-iota also promotes invasion, chemoresistance, and tumor cell survival. Expression profiling of PKC-iota is a prognostic marker of poor clinical outcome in several human cancers. PKC-iota also plays a role in establishing cell polarity, and has critical embryonic functions. Members of this family contain one C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410344 Cd Length: 55 Bit Score: 41.87 E-value: 7.55e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1039770412 932 RFNvglnmRATKCAVCLDTV-HFGRQASKCLECQVMCHPKCSTCLPATCG 980
Cdd:cd20794 9 RFN-----RRAVCAYCSDRIwGLGRQGYKCINCKLLVHKKCHKLVKVACG 53
|
|
| PH_MRCK |
cd01243 |
MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain; MRCK ... |
1015-1130 |
7.98e-05 |
|
MRCK (myotonic dystrophy-related Cdc42-binding kinase) pleckstrin homology (PH) domain; MRCK is thought to be coincidence detector of signaling by Cdc42 and phosphoinositides. It has been shown to promote cytoskeletal reorganization, which affects many biological processes. There are 2 members of this family: MRCKalpha and MRCKbeta. MRCK consists of a serine/threonine kinase domain, a cysteine rich (C1) region, a PH domain and a p21 binding motif. The MRCK PH domain is responsible for its targeting to cell to cell junctions. PH domains have diverse functions, but in general are involved in targeting proteins to the appropriate cellular location or in the interaction with a binding partner. They share little sequence conservation, but all have a common fold, which is electrostatically polarized. Less than 10% of PH domains bind phosphoinositide phosphates (PIPs) with high affinity and specificity. PH domains are distinguished from other PIP-binding domains by their specific high-affinity binding to PIPs with two vicinal phosphate groups: PtdIns(3,4)P2, PtdIns(4,5)P2 or PtdIns(3,4,5)P3 which results in targeting some PH domain proteins to the plasma membrane. A few display strong specificity in lipid binding. Any specificity is usually determined by loop regions or insertions in the N-terminus of the domain, which are not conserved across all PH domains. PH domains are found in cellular signaling proteins such as serine/threonine kinase, tyrosine kinases, regulators of G-proteins, endocytotic GTPases, adaptors, as well as cytoskeletal associated molecules and in lipid associated enzymes.
Pssm-ID: 269949 Cd Length: 135 Bit Score: 44.21 E-value: 7.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 1015 EGWMKVPrnnKRG--QQGWDRKYIVLEGSKVLIYD-NEAREAGQRPVEEFELCLPDGDVSIhGAVGASELANTAKADVPY 1091
Cdd:cd01243 15 EGYVRVP---KPGgvKKGWQRQFAVVCDFKLFLFDiSEDKASQPSQVASQVLDMRDEEFSV-SSVLASDVIHANKKDIPC 90
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1039770412 1092 ILKME-SHPHTTCWPGRTLyLLAPSFPDKQRWVTALESVV 1130
Cdd:cd01243 91 IFRVSaSQLAPPSLKFSLL-MLADSENEKQKWVDALNELH 129
|
|
| C1_Munc13-1 |
cd20858 |
protein kinase C conserved region 1 (C1 domain) found in Munc13-1 and similar proteins; ... |
929-979 |
8.24e-05 |
|
protein kinase C conserved region 1 (C1 domain) found in Munc13-1 and similar proteins; Munc13-1, also called protein unc-13 homolog A (Unc13A), is a diacylglycerol (DAG) receptor that plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). Loss of MUNC13-1 function causes microcephaly, cortical hyperexcitability, and fatal myasthenia. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410408 Cd Length: 60 Bit Score: 42.00 E-value: 8.24e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1039770412 929 IPHRFNVGLNMRATKCAVCLDTV-HFGRQASKCLECQVMCHPKCSTCLPATC 979
Cdd:cd20858 6 TPHNFEVWTATTPTYCYECEGLLwGIARQGMRCTECGVKCHEKCQDLLNADC 57
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
68-622 |
8.32e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 47.74 E-value: 8.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 68 EVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLM-----MNQL------EEDLVSARRRSDLYESELRESRLA 136
Cdd:TIGR01612 1230 KIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMdikaeMETFnishddDKDHHIISKKHDENISDIREKSLK 1309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 137 -AEEFKRKAN------ECQHKLMKAKDQGKpEVGEYskLEKI-NAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKE 208
Cdd:TIGR01612 1310 iIEDFSEESDindikkELQKNLLDAQKHNS-DINLY--LNEIaNIYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDELD 1386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 209 RAERELEKLhnREDSSEGIKKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQV 288
Cdd:TIGR01612 1387 KSEKLIKKI--KDDINLEECKSKIESTLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADN 1464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 289 SAQHLevhLKQKEQHYEEKIKVLDNQIKKDLaDKEslenmmQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELS 368
Cdd:TIGR01612 1465 KSQHI---LKIKKDNATNDHDFNINELKEHI-DKS------KGCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALA 1534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 369 EANKLAansslftqRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEqlEKISHQD---HSDKSrlleletrlrevs 445
Cdd:TIGR01612 1535 IKNKFA--------KTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKK--EKFRIEDdaaKNDKS------------- 1591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 446 leheeqklelKRQLTELQLSLQERESQLTALQAARAALESQLRQAkteleettaeaeeeiqaltahrDEIQRKFDALR-- 523
Cdd:TIGR01612 1592 ----------NKAAIDIQLSLENFENKFLKISDIKKKINDCLKET----------------------ESIEKKISSFSid 1639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 524 NSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRRE----ITEREMQLT-SQKQTMEAL 598
Cdd:TIGR01612 1640 SQDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNyeigIIEKIKEIAiANKEEIESI 1719
|
570 580 590
....*....|....*....|....*....|.
gi 1039770412 599 KTTCTMLEEQVL------DLEALN-DELLEK 622
Cdd:TIGR01612 1720 KELIEPTIENLIssfntnDLEGIDpNEKLEE 1750
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
352-521 |
8.40e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 45.69 E-value: 8.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 352 AMDSKIRSLEQRIVELSEAnklaansslftqrnmkaqeemISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDK 431
Cdd:COG1579 14 ELDSELDRLEHRLKELPAE---------------------LAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 432 SRLLELETRLREVS-------LEHEEQKLELKRQLTELQLS-----LQERESQLTALQAARAALESQLRQAKTELEETTA 499
Cdd:COG1579 73 ARIKKYEEQLGNVRnnkeyeaLQKEIESLKRRISDLEDEILelmerIEELEEELAELEAELAELEAELEEKKAELDEELA 152
|
170 180
....*....|....*....|..
gi 1039770412 500 EAEEEIQALTAHRDEIQRKFDA 521
Cdd:COG1579 153 ELEAELEELEAEREELAAKIPP 174
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
450-741 |
9.58e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 46.06 E-value: 9.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 450 EQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDeiqrKFDALRNSctvI 529
Cdd:COG1340 1 SKTDELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELRE----KRDELNEK---V 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 530 TDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEqV 609
Cdd:COG1340 74 KELKEERDELNEKLNELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPEEEKELVEKIKELEKELEK-A 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 610 LDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQrITESRqvvelavKEHKAEILALQQA 689
Cdd:COG1340 153 KKALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADE-LRKEA-------DELHKEIVEAQEK 224
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1039770412 690 LKEQKLKAESLSDKLNDLEKKHAMLEmnarslQQKLETERELKQRLLEEQAK 741
Cdd:COG1340 225 ADELHEEIIELQKELRELRKELKKLR------KKQRALKREKEKEELEEKAE 270
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
461-859 |
1.03e-04 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 46.99 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 461 ELQLSLQERESQLTALQAARAALESQLRQAKteleettaeaeeeiqaltahrdEIQRKFDALRNSCTVIT----DLEEQL 536
Cdd:pfam05622 11 ELAQRCHELDQQVSLLQEEKNSLQQENKKLQ----------------------ERLDQLESGDDSGTPGGkkylLLQKQL 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 537 NQLTEDN--------------AELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRrEITER----EMQLTSQKQTMEA- 597
Cdd:pfam05622 69 EQLQEENfrletarddyrikcEELEKEVLELQHRNEELTSLAEEAQALKDEMDILR-ESSDKvkklEATVETYKKKLEDl 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 598 --LKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQfecrVRELQRMLDTE-----------KQSRA----- 659
Cdd:pfam05622 148 gdLRRQVKLLEERNAEYMQRTLQLEEELKKANALRGQLETYKRQ----VQELHGKLSEEskkadklefeyKKLEEkleal 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 660 -RADQRITESRQVVELAVKE-----------HKAEILALQQALKEQKLKAESLS----DKLNDLEKKHAMLEMNAR---- 719
Cdd:pfam05622 224 qKEKERLIIERDTLRETNEElrcaqlqqaelSQADALLSPSSDPGDNLAAEIMPaeirEKLIRLQHENKMLRLGQEgsyr 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 720 ----SLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLEniQVLYSHEKvkm 795
Cdd:pfam05622 304 erltELQQLLEDANRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEEHLE--KLHEAQSE--- 378
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770412 796 egtISQQTKLIDFLQAKMDQPAKKKkvplqynelklalekekarCAELEEALQKTRIELRSARE 859
Cdd:pfam05622 379 ---LQKKKEQIEELEPKQDSNLAQK-------------------IDELQEALRKKDEDMKAMEE 420
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
9-372 |
1.12e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 46.94 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 9 MEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSR 88
Cdd:TIGR04523 340 LNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQ 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 89 KLQEIkEQEYQaqveemrlmmNQLEEDLVSARRRSDLyESELRESRLAAEEFKRKANECQHKLMKAKDQGKpevGEYSKL 168
Cdd:TIGR04523 420 EKELL-EKEIE----------RLKETIIKNNSEIKDL-TNQDSVKELIIKNLDNTRESLETQLKVLSRSIN---KIKQNL 484
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 169 EKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERaERELEKLHNRedssegIKKKLVeaeerrhSLENKVKRL 248
Cdd:TIGR04523 485 EQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEK-IEKLESEKKE------KESKIS-------DLEDELNKD 550
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 249 ETMERRENrLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLE---VHLKQKEQHYEEKIKVLDNQI-------KKD 318
Cdd:TIGR04523 551 DFELKKEN-LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEkekKDLIKEIEEKEKKISSLEKELekakkenEKL 629
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1039770412 319 LADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANK 372
Cdd:TIGR04523 630 SSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIELMK 683
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
141-309 |
1.13e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 46.69 E-value: 1.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 141 KRKANECQHKLMKAKDQGKPEVGEYSKLEKINAEQqlKIQELQEKLEKAVKAST-EATELLQNIRQAKERAERELEKLHN 219
Cdd:PRK12704 30 EAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKE--EIHKLRNEFEKELRERRnELQKLEKRLLQKEENLDRKLELLEK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 220 REDssegikkklvEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQM----ADKILeLEEKHREAQVSAQHLev 295
Cdd:PRK12704 108 REE----------ELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLtaeeAKEIL-LEKVEEEARHEAAVL-- 174
|
170
....*....|....
gi 1039770412 296 hLKQKEQHYEEKIK 309
Cdd:PRK12704 175 -IKEIEEEAKEEAD 187
|
|
| C1_nPKC_theta-like_rpt2 |
cd20837 |
second protein kinase C conserved region 1 (C1 domain) found in novel protein kinase C (nPKC) ... |
931-979 |
1.18e-04 |
|
second protein kinase C conserved region 1 (C1 domain) found in novel protein kinase C (nPKC) theta, delta, and similar proteins; PKCs are classified into three groups (classical, atypical, and novel) depending on their mode of activation and the structural characteristics of their regulatory domain. nPKCs are calcium-independent, but require DAG (1,2-diacylglycerol) and phosphatidylserine (PS) for activity. PKC-theta is selectively expressed in T-cells and plays an important and non-redundant role in several aspects of T-cell biology. PKC-delta plays a role in cell cycle regulation and programmed cell death in many cell types. Members of this family contain two copies of C1 domain. This model corresponds to the second one. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410387 Cd Length: 50 Bit Score: 41.27 E-value: 1.18e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1039770412 931 HRFNVGLNMRATKCAVClDTVHFG--RQASKCLECQVMCHPKCSTCLPATC 979
Cdd:cd20837 1 HRFKVYNYMSPTFCDHC-GSLLWGlfRQGLKCEECGMNVHHKCQKKVANLC 50
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
2-245 |
1.21e-04 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 46.82 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 2 LLGEEAMMEQEMTRLHRRVSEVEA---VLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEqarMEVSQEDDKALQ 78
Cdd:PLN02939 161 ILTEKEALQGKINILEMRLSETDArikLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLS---KELDVLKEENML 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 79 LLHDIREQSRKLQEIKE-QEYQAQVEEMRLMMNQLEEDLVSarRRSDLYESELRESRLAAEEFKRKANECQHKLMKAKDQ 157
Cdd:PLN02939 238 LKDDIQFLKAELIEVAEtEERVFKLEKERSLLDASLRELES--KFIVAQEDVSKLSPLQYDCWWEKVENLQDLLDRATNQ 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 158 gkpeVGEYSKLEKINAEQQLKIQELQEKLEKAV--KASTEATELLQN-IRQAKERAERELEKLHNR----EDSSEGIK-- 228
Cdd:PLN02939 316 ----VEKAALVLDQNQDLRDKVDKLEASLKEANvsKFSSYKVELLQQkLKLLEERLQASDHEIHSYiqlyQESIKEFQdt 391
|
250
....*....|....*...
gi 1039770412 229 -KKLVEAEERRhSLENKV 245
Cdd:PLN02939 392 lSKLKEESKKR-SLEHPA 408
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
657-892 |
1.36e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.36 E-value: 1.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 657 SRARADQRITESRQvvelAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLET-ERELKQR- 734
Cdd:COG3883 10 TPAFADPQIQAKQK----ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEaEAEIEERr 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 735 -LLEEQAKLQQQMDLQKNHIFRLT--QGLQEALDRADLLKT---------------------ERSDLEYQLENIQVL--- 787
Cdd:COG3883 86 eELGERARALYRSGGSVSYLDVLLgsESFSDFLDRLSALSKiadadadlleelkadkaeleaKKAELEAKLAELEALkae 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 788 YSHEKVKMEGTISQQTKLIDFLQAKMDqpakkkkvplQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKAT 867
Cdd:COG3883 166 LEAAKAELEAQQAEQEALLAQLSAEEA----------AAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
|
250 260
....*....|....*....|....*
gi 1039770412 868 DHPHPSTPATARQQIAMSAIVRSPE 892
Cdd:COG3883 236 AAAAAAAAASAAGAGAAGAAGAAAG 260
|
|
| C1_aPKC_iota |
cd21094 |
protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) ... |
931-982 |
1.44e-04 |
|
protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) iota type; PKCs are classified into three groups (classical, atypical, and novel) depending on their mode of activation and the structural characteristics of their regulatory domain. aPKCs only require phosphatidylserine (PS) for activation. They contain a C2-like region, instead of a calcium-binding (C2) region found in classical PKCs, in their regulatory domain. There are two aPKC isoforms, zeta and iota. aPKCs are involved in many cellular functions including proliferation, migration, apoptosis, polarity maintenance and cytoskeletal regulation. They also play a critical role in the regulation of glucose metabolism and in the pathogenesis of type 2 diabetes. PKC-iota is directly implicated in carcinogenesis. It is critical to oncogenic signaling mediated by Ras and Bcr-Abl. The PKC-iota gene is the target of tumor-specific gene amplification in many human cancers, and has been identified as a human oncogene. In addition to its role in transformed growth, PKC-iota also promotes invasion, chemoresistance, and tumor cell survival. Expression profiling of PKC-iota is a prognostic marker of poor clinical outcome in several human cancers. PKC-iota also plays a role in establishing cell polarity, and has critical embryonic functions. Members of this family contain C1 domain found in aPKC isoform iota. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410447 Cd Length: 55 Bit Score: 41.14 E-value: 1.44e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1039770412 931 HRFNVGLNMRATKCAVCLDTV-HFGRQASKCLECQVMCHPKCSTCLPATCGLP 982
Cdd:cd21094 3 HTFQAKRFNRRAHCAICTDRIwGLGRQGYKCINCKLLVHKKCHKLVTIECGRH 55
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
41-491 |
1.52e-04 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 46.49 E-value: 1.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 41 RSLLEQDLATYITECSSLK---RSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQ-AQVEEMRLMMNQLEEDL 116
Cdd:COG5185 120 ISLLYLYKSEIVALKDELIkveKLDEIADIEASYGEVETGIIKDIFGKLTQELNQNLKKLEIfGLTLGLLKGISELKKAE 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 117 VSARRRSDLYESELRES------RLAAEEFKRKANEcqhKLMKAKDQGKPEVGEYS-KLEK-INAEQQLKIQELQEKLEK 188
Cdd:COG5185 200 PSGTVNSIKESETGNLGsestllEKAKEIINIEEAL---KGFQDPESELEDLAQTSdKLEKlVEQNTDLRLEKLGENAES 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 189 AVKASTEATELLQNIRQAKERAeRELEKLHNREDSSEGIKKKLVEAEERRHsLENKVKRLETMerrenrlkddIQTKSEQ 268
Cdd:COG5185 277 SKRLNENANNLIKQFENTKEKI-AEYTKSIDIKKATESLEEQLAAAEAEQE-LEESKRETETG----------IQNLTAE 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 269 IQQMADKILELEEKHREaQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQka 348
Cdd:COG5185 345 IEQGQESLTENLEAIKE-EIENIVGEVELSKSSEELDSFKDTIESTKESLDEIPQNQRGYAQEILATLEDTLKAADRQ-- 421
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 349 mINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLEtqagkLEAQNRKLEEQLEKIshqdh 428
Cdd:COG5185 422 -IEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYDEINRS-----VRSKKEDLNEELTQI----- 490
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039770412 429 sdKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQEREsqlTALQAARAALESQLRQAK 491
Cdd:COG5185 491 --ESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFM---RARGYAHILALENLIPAS 548
|
|
| Filament |
pfam00038 |
Intermediate filament protein; |
356-652 |
1.56e-04 |
|
Intermediate filament protein;
Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 45.68 E-value: 1.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 356 KIRSLEQRIVEL-SEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKIshqdhsdKSRL 434
Cdd:pfam00038 19 KVRFLEQQNKLLeTKISELRQKKGAEPSRLYSLYEKEIEDLRRQLDTLTVERARLQLELDNLRLAAEDF-------RQKY 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 435 lELETRLREvslEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALE-------SQLRQAKTELEETTAEAEEEIQA 507
Cdd:pfam00038 92 -EDELNLRT---SAENDLVGLRKDLDEATLARVDLEAKIESLKEELAFLKknheeevRELQAQVSDTQVNVEMDAARKLD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 508 LTAHRDEIQRKFDALRNSCTviTDLEEQLNQLTEdnaELNnqnfylskqlDEASGANDEIVQLRSEVDHLRREITEREMQ 587
Cdd:pfam00038 168 LTSALAEIRAQYEEIAAKNR--EEAEEWYQSKLE---ELQ----------QAAARNGDALRSAKEEITELRRTIQSLEIE 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 588 LTSQKQTMEALKTTCTMLEEQ-VLDLEALNDELLEKERQweawrsvLGDEKSQFECRVRELQRMLD 652
Cdd:pfam00038 233 LQSLKKQKASLERQLAETEERyELQLADYQELISELEAE-------LQETRQEMARQLREYQELLN 291
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
462-781 |
1.76e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 46.04 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 462 LQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRkfdALRNSCTVITDLEEQLNQLTE 541
Cdd:pfam07888 32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKE---ELRQSREKHEELEEKYKELSA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 542 DNAELNNQNFYLSKQLDEASGandEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLE 621
Cdd:pfam07888 109 SSEELSEEKDALLAQRAAHEA---RIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEE 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 622 KERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVvelavkehKAEILALQQALKEQKLKAESLS 701
Cdd:pfam07888 186 ELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEAL--------LEELRSLQERLNASERKVEGLG 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 702 DKLNDL--EKKHAMLEMNARSLQ------QKLETE---RELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLL 770
Cdd:pfam07888 258 EELSSMaaQRDRTQAELHQARLQaaqltlQLADASlalREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEE 337
|
330
....*....|.
gi 1039770412 771 KTERSDLEYQL 781
Cdd:pfam07888 338 RMEREKLEVEL 348
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
198-536 |
1.77e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 46.04 E-value: 1.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 198 ELLQNIRQAKERAERELEKLHnrEDSSEGIKKKLVEAEERRHSLENKVKRLETmerrenrlkdDIQTKSEQIQQMADKIL 277
Cdd:pfam07888 30 ELLQNRLEECLQERAELLQAQ--EAANRQREKEKERYKRDREQWERQRRELES----------RVAELKEELRQSREKHE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 278 ELEEKHREAQVS----AQHLEVHLKQKEQH------YEEKIKVLD---------------------NQIKKDLADKESLE 326
Cdd:pfam07888 98 ELEEKYKELSASseelSEEKDALLAQRAAHearireLEEDIKTLTqrvleretelermkerakkagAQRKEEEAERKQLQ 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 327 NMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSeaNKLAAnsslfTQRNMKAQEEMISELRQQKFYLETQA 406
Cdd:pfam07888 178 AKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLT--QKLTT-----AHRKEAENEALLEELRSLQERLNASE 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 407 GKLEAQNRKLEEQlekISHQDHS----DKSRL--LELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAAR 480
Cdd:pfam07888 251 RKVEGLGEELSSM---AAQRDRTqaelHQARLqaAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAEL 327
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 481 AALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQL 536
Cdd:pfam07888 328 QRLEERLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQL 383
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
254-574 |
1.77e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 46.49 E-value: 1.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 254 RENRLKD---DIQTKSEQIQQMADKILELEEKHREA-QVSAQHLEVHLkqkEQHYEEKIKVLD---NQIKKDLADKESLE 326
Cdd:PRK04863 784 REKRIEQlraEREELAERYATLSFDVQKLQRLHQAFsRFIGSHLAVAF---EADPEAELRQLNrrrVELERALADHESQE 860
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 327 nmmQRHEEEAhekgKILSEQKAMINAMDSKIR-----SLEQRIVELSEANKLAANSSLFTQRNMKA-------------Q 388
Cdd:PRK04863 861 ---QQQRSQL----EQAKEGLSALNRLLPRLNlladeTLADRVEEIREQLDEAEEAKRFVQQHGNAlaqlepivsvlqsD 933
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 389 EEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLL----ELETRLREVSLEHEEQKLELKRQLTELQL 464
Cdd:PRK04863 934 PEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAHFSYEDAAEMLaknsDLNEKLRQRLEQAEQERTRAREQLRQAQA 1013
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 465 SLQERESQLTALQAARAALESQLRQAKTELEET-TAEAEEEIQALTAHRDEIQrkfDALRNSCTVITDLEEQLnQLTEdn 543
Cdd:PRK04863 1014 QLAQYNQVLASLKSSYDAKRQMLQELKQELQDLgVPADSGAEERARARRDELH---ARLSANRSRRNQLEKQL-TFCE-- 1087
|
330 340 350
....*....|....*....|....*....|.
gi 1039770412 544 AELNNQNfylsKQLDEasgANDEIVQLRSEV 574
Cdd:PRK04863 1088 AEMDNLT----KKLRK---LERDYHEMREQV 1111
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
440-767 |
1.91e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 46.49 E-value: 1.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 440 RLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEEttaeaeeeIQALTAHRDEIQRKF 519
Cdd:PRK04863 283 VHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNL--------VQTALRQQEKIERYQ 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 520 DALrnsctviTDLEEQLNQLTEDNAELNNQNFYLSKQLDEAsgaNDEIVQLRSEV-DHLRR--EITEREMQLTSQKQTME 596
Cdd:PRK04863 355 ADL-------EELEERLEEQNEVVEEADEQQEENEARAEAA---EEEVDELKSQLaDYQQAldVQQTRAIQYQQAVQALE 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 597 ALKTTC-----------TMLEEQVLDLEALNDELLEKERQWeawrSVLGDEKSQFECRVRELQRMLDTEKQSRAR--ADQ 663
Cdd:PRK04863 425 RAKQLCglpdltadnaeDWLEEFQAKEQEATEELLSLEQKL----SVAQAAHSQFEQAYQLVRKIAGEVSRSEAWdvARE 500
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 664 RITESRQVVELAVKEH--KAEILALQQALKEQKlKAESLsdkLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAK 741
Cdd:PRK04863 501 LLRRLREQRHLAEQLQqlRMRLSELEQRLRQQQ-RAERL---LAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSE 576
|
330 340
....*....|....*....|....*.
gi 1039770412 742 LQQQMDLQKNHIFRLTQGLQEALDRA 767
Cdd:PRK04863 577 ARERRMALRQQLEQLQARIQRLAARA 602
|
|
| C1_MTMR-like |
cd20828 |
protein kinase C conserved region 1 (C1 domain) found in uncharacterized proteins similar to ... |
927-980 |
1.92e-04 |
|
protein kinase C conserved region 1 (C1 domain) found in uncharacterized proteins similar to myotubularin-related proteins; The family includes a group of uncharacterized proteins that show high sequence similarity to vertebrate myotubularin-related proteins (MTMRs), such as MTMR5 and MTMR13. MTMRs may function as guanine nucleotide exchange factors (GEFs). Vertebrate MTMR5 and MTMR13 contain an N-terminal DENN domain, a PH-GRAM domain, an inactive PTP domain, a SET interaction domain, a coiled-coil domain, and a C-terminal PH domain. Members of this family contain these domains and have an additional C1 domain. This model corresponds to the C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410378 Cd Length: 57 Bit Score: 40.89 E-value: 1.92e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1039770412 927 HNIPHRFNVGLNMRATKCAVCLDTV-HFGRQASKCLECQVMCHPKCSTCLPATCG 980
Cdd:cd20828 2 FTQPHNFEPHSFVTPTNCDYCLQILwGIVKKGMKCSECGYNCHEKCQPQVPKQCS 56
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
662-819 |
1.92e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.92 E-value: 1.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 662 DQRITESRQvvelAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLEterELKQRLLE---- 737
Cdd:COG1579 16 DSELDRLEH----RLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIK---KYEEQLGNvrnn 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 738 -EQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQP 816
Cdd:COG1579 89 kEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168
|
...
gi 1039770412 817 AKK 819
Cdd:COG1579 169 AAK 171
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
68-619 |
1.93e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 46.58 E-value: 1.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 68 EVSQEDDKALQLLHDIREQSRKLQEIKEQEyQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRK-ANE 146
Cdd:TIGR01612 1112 EINKIKDDIKNLDQKIDHHIKALEEIKKKS-ENYIDEIKAQINDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKnIYD 1190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 147 CQHKLMKAKDQGKPEVGEYSKLEKINAE--QQL------KIQELQEKLEKAVKASTEATELLQNIRQAKERAERELeklh 218
Cdd:TIGR01612 1191 EIKKLLNEIAEIEKDKTSLEEVKGINLSygKNLgklfleKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEM---- 1266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 219 nredSSEGIKKKLVEAEERRHSlenKVKRLETMERRENRLKDDIQTKSEQIQQ-------MADKILELEEKHREAQVSAQ 291
Cdd:TIGR01612 1267 ----GIEMDIKAEMETFNISHD---DDKDHHIISKKHDENISDIREKSLKIIEdfseesdINDIKKELQKNLLDAQKHNS 1339
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 292 HLEVHLKQ------------------KEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAM-INA 352
Cdd:TIGR01612 1340 DINLYLNEianiynilklnkikkiidEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEECKSKIESTLDDKdIDE 1419
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 353 MDSKIRSLEQRIVE-----------LSEANK----------LAANSSLFTQRNMK--AQEEM---ISELRQQKfyleTQA 406
Cdd:TIGR01612 1420 CIKKIKELKNHILSeesnidtyfknADENNEnvlllfknieMADNKSQHILKIKKdnATNDHdfnINELKEHI----DKS 1495
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 407 GKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLelKRQLTELQLSLQERESQLTaLQAARAalESQ 486
Cdd:TIGR01612 1496 KGCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKT--KKDSEIIIKEIKDAHKKFI-LEAEKS--EQK 1570
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 487 LRQAKTELEETTAEAEEEIQALTAHRDeIQRKFDALRNSCTVITDLEEQLNQ-LTEDNAelnnqnfyLSKQLDEASgand 565
Cdd:TIGR01612 1571 IKEIKKEKFRIEDDAAKNDKSNKAAID-IQLSLENFENKFLKISDIKKKINDcLKETES--------IEKKISSFS---- 1637
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 1039770412 566 eivqlrseVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDEL 619
Cdd:TIGR01612 1638 --------IDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEI 1683
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
181-679 |
1.94e-04 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 46.36 E-value: 1.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 181 ELQEKLEKAVKASTEATELlQNIRQAKERAERELEKLHNREDSSEGIKKK--LVEAEERRHSLE---------NKV---- 245
Cdd:PTZ00440 2171 EIIENIKKEIIEINENTEM-NTLENTADKLKELYENLKKKKNIINNIYKKinFIKLQEIENSSEkyndisklfNNVvetq 2249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 246 -KRLETMERRENRLKDDIQTKsEQIQQMADKILELEEKhREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKdladKES 324
Cdd:PTZ00440 2250 kKKLLDNKNKINNIKDKINDK-EKELINVDSSFTLESI-KTFNEIYDDIKSNIGDLYKLEDTNNDELKKVKLY----IEN 2323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 325 LENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLfTQRNMKAQEEMISELRQQKFYLET 404
Cdd:PTZ00440 2324 ITHLLNRINTLINDLDNYQDENYGKDKNIELNNENNSYIIKTKEKINNLKEEFSK-LLKNIKRNNTLCNNNNIKDFISNI 2402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 405 qAGKLEAQNRKLEEQLEkishqdhsdksrlleletrLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALE 484
Cdd:PTZ00440 2403 -GKSVETIKQRFSSNLP-------------------EKEKLHQIEENLNEIKNIMNETKRISNVDAFTNKILQDIDNEKN 2462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 485 sqlrqaKTELEETTAEAEEEIQALTAHRDEIQRKF----DALRNSCTVITDLEEQLNQLTEDNAELNNQ-NFYLSKQLDE 559
Cdd:PTZ00440 2463 ------KENNNMNAEKIDDLIENVTSHNEKIKSELliinDALRRVKEKKDEMNKLFNSLTENNNNNNNSaKNIVDNSTYI 2536
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 560 ASGANDEIVQLRSEVDHLRREITEREMQLTSqkqtmealkttctMLEEQVLDLEALNDELLEKERQweawrsvlGDEKSQ 639
Cdd:PTZ00440 2537 INELESHVSKLNELLSYIDNEIKELENEKLK-------------LLEKAKIEESRKERERIESETQ--------EDNTDE 2595
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 1039770412 640 FECRVRELQRMLDTEKQsRARADQRITESRQVVELAVKEH 679
Cdd:PTZ00440 2596 EQINRQQQERLQKEEEQ-KAYSQERLNREVSGTDDTNKNH 2634
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
173-477 |
2.00e-04 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 45.57 E-value: 2.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 173 AEQQLKIQELQEKLEKAVKASTEATELLQNIR-QAKERAERElEKLHNREDSSEGIKKKLVEAEERRHSLENKVKRLETM 251
Cdd:pfam15905 52 TARKVKSLELKKKSQKNLKESKDQKELEKEIRaLVQERGEQD-KRLQALEEELEKVEAKLNAAVREKTSLSASVASLEKQ 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 252 ERRENRLKDDIQTK-SEQIQQMADKILELEekhreaqVSAQHLEVHLKQKEqhyeekikVLDNQIKKDLADKESLENMMQ 330
Cdd:pfam15905 131 LLELTRVNELLKAKfSEDGTQKKMSSLSME-------LMKLRNKLEAKMKE--------VMAKQEGMEGKLQVTQKNLEH 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 331 RHEEEAHEKGKILSEQKAMINAmDSKIRSLEQRIVELSEANKLAANSSLftqrnmkaqeemisELRQQKFYLETQAGKLE 410
Cdd:pfam15905 196 SKGKVAQLEEKLVSTEKEKIEE-KSETEKLLEYITELSCVSEQVEKYKL--------------DIAQLEELLKEKNDEIE 260
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039770412 411 AQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQ 477
Cdd:pfam15905 261 SLKQSLEEKEQELSKQIKDLNEKCKLLESEKEELLREYEEKEQTLNAELEELKEKLTLEEQEHQKLQ 327
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
449-663 |
2.10e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.59 E-value: 2.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 449 EEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRN---- 524
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGErara 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 525 ---SCTVITDLEEQLNQltEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTT 601
Cdd:COG3883 95 lyrSGGSVSYLDVLLGS--ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039770412 602 ctmLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQ 663
Cdd:COG3883 173 ---LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
183-477 |
2.29e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 45.88 E-value: 2.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 183 QEKLEKAVKasteatellQNIRQAKERAERELEKlhnredssegiKKKLVEAEERRHSlenKVKRLETMERRENRLKDDI 262
Cdd:pfam17380 290 QEKFEKMEQ---------ERLRQEKEEKAREVER-----------RRKLEEAEKARQA---EMDRQAAIYAEQERMAMER 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 263 QTKSEQIQQmadkilelEEKHREAQvsaqhlevHLKQKEQHYE-EKIKVLDNqikkdLADKESLENMMQRHEEEAHEKGK 341
Cdd:pfam17380 347 ERELERIRQ--------EERKRELE--------RIRQEEIAMEiSRMRELER-----LQMERQQKNERVRQELEAARKVK 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 342 ILSEQKAminamdskiRSLEQRIVELSEANKLAANSSlftQRNMKAQEEMISElrqqkfylETQAGKLEAQNRklEEQLE 421
Cdd:pfam17380 406 ILEEERQ---------RKIQQQKVEMEQIRAEQEEAR---QREVRRLEEERAR--------EMERVRLEEQER--QQQVE 463
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 422 KISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQ 477
Cdd:pfam17380 464 RLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLE 519
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
131-351 |
2.42e-04 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 45.98 E-value: 2.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 131 RESRLAAEEFKRKANECQHKLMKAKDQGKPEVGEYSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERA 210
Cdd:PTZ00440 435 LYSNLEIIEIKKKYDEKINELKKSINQLKTLISIMKSFYDLIISEKDSMDSKEKKESSDSNYQEKVDELLQIINSIKEKN 514
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 211 ERELEKLHNREDSS---EGIKKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQ 287
Cdd:PTZ00440 515 NIVNNNFKNIEDYYitiEGLKNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDIKNKIKYIEENVDHIKDIISLNDEID 594
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770412 288 VSAQHLE----VHLKQKEQHYEEKIK-------VLDNQIKKDLADKES-LENMMQRHE---EEAHEKGKILSEQKAMIN 351
Cdd:PTZ00440 595 NIIQQIEelinEALFNKEKFINEKNDlqekvkyILNKFYKGDLQELLDeLSHFLDDHKylyHEAKSKEDLQTLLNTSKN 673
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
10-213 |
2.56e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.83 E-value: 2.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 10 EQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRK 89
Cdd:TIGR02169 818 EQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ 897
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 90 L--QEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRE------SRLAAEEFKRKANECQHKLMKAKDQGKPE 161
Cdd:TIGR02169 898 LreLERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeEELSLEDVQAELQRVEEEIRALEPVNMLA 977
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1039770412 162 VGEYsklekinAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERE 213
Cdd:TIGR02169 978 IQEY-------EEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFME 1022
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
527-746 |
2.65e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 2.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 527 TVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASG----ANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEAL---- 598
Cdd:COG3883 16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEeyneLQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaral 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 599 ---KTTCTMLEeQVLDLEALNDELlekeRQWEAWRSVLGDEKSQFEcRVRELQRMLDTEKQSRARADQRITESRQVVELA 675
Cdd:COG3883 96 yrsGGSVSYLD-VLLGSESFSDFL----DRLSALSKIADADADLLE-ELKADKAELEAKKAELEAKLAELEALKAELEAA 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770412 676 VKEhkaeilaLQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQM 746
Cdd:COG3883 170 KAE-------LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAA 233
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
203-356 |
2.66e-04 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 45.59 E-value: 2.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 203 IRQAKERAERELEKLhnrEDSSEGIKKKLVEAEERRHSLENKVKRLEtmerrenRLKDDIQTKSEQIQQMADKIL-ELEE 281
Cdd:PRK00409 504 IEEAKKLIGEDKEKL---NELIASLEELERELEQKAEEAEALLKEAE-------KLKEELEEKKEKLQEEEDKLLeEAEK 573
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 282 KHREA-------------QVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKdlADKESLENMMQRHEEEAHEKGKILS-EQK 347
Cdd:PRK00409 574 EAQQAikeakkeadeiikELRQLQKGGYASVKAHELIEARKRLNKANEK--KEKKKKKQKEKQEELKVGDEVKYLSlGQK 651
|
....*....
gi 1039770412 348 AMINAMDSK 356
Cdd:PRK00409 652 GEVLSIPDD 660
|
|
| C1_PKD2_rpt2 |
cd20843 |
second protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and ... |
929-979 |
2.79e-04 |
|
second protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins; PKD2, also called PRKD2, HSPC187, or serine/threonine-protein kinase D2 (nPKC-D2), is a serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of cell proliferation via MAPK1/3 (ERK1/2) signaling, oxidative stress-induced NF-kappa-B activation, inhibition of HDAC7 transcriptional repression, signaling downstream of T-cell antigen receptor (TCR) and cytokine production, and plays a role in Golgi membrane trafficking, angiogenesis, secretory granule release and cell adhesion. PKD2 contains N-terminal tandem cysteine-rich zinc binding C1 (PKC conserved region 1), central PH (Pleckstrin Homology), and C-terminal catalytic kinase domains. This model corresponds to the second C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410393 Cd Length: 79 Bit Score: 41.11 E-value: 2.79e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1039770412 929 IPHRFNVGLNMRATKCAVCLDTVH-FGRQASKCLECQVMCHPKCSTCLPATC 979
Cdd:cd20843 10 VPHTFVIHSYTRPTVCQFCKKLLKgLFRQGLQCKDCKFNCHKRCATRVPNDC 61
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
164-341 |
2.79e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.14 E-value: 2.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 164 EYSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERR----- 238
Cdd:COG4942 35 EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELlraly 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 239 --------------HSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHY 304
Cdd:COG4942 115 rlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALK 194
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1039770412 305 EEKIKVLD----------NQIKKDLADKESLENMMQRHEEEAHEKGK 341
Cdd:COG4942 195 AERQKLLArlekelaelaAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
52-372 |
2.79e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 45.81 E-value: 2.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 52 ITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSrKLQEIKEQEYQA----QVEEMRLMMNQLEEDLVSARRRSDLYE 127
Cdd:TIGR01612 1364 IDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDI-NLEECKSKIESTlddkDIDECIKKIKELKNHILSEESNIDTYF 1442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 128 SELRESR----LAAEEFKRKANECQHKLMKAKDQGkpevgeysklekiNAEQQLKIQELQEKLEKAVKASTEATELLQNI 203
Cdd:TIGR01612 1443 KNADENNenvlLLFKNIEMADNKSQHILKIKKDNA-------------TNDHDFNINELKEHIDKSKGCKDEADKNAKAI 1509
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 204 RQAK---ERAERELEKLHNREDSSEgIKKKLVEAEERRHSLENKVKRL--------ETMERRENRLKD------------ 260
Cdd:TIGR01612 1510 EKNKelfEQYKKDVTELLNKYSALA-IKNKFAKTKKDSEIIIKEIKDAhkkfileaEKSEQKIKEIKKekfrieddaakn 1588
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 261 --------DIQTKSEQIQQMADKILELEEKHREAqvsaqhlevhLKQKEQhYEEKIKVLD-NQIKKDLADKESLENMMQR 331
Cdd:TIGR01612 1589 dksnkaaiDIQLSLENFENKFLKISDIKKKINDC----------LKETES-IEKKISSFSiDSQDTELKENGDNLNSLQE 1657
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 332 HEEEAHEKGKILSEQKAMINAMDSKIRSLE---------------QRIVELSEANK 372
Cdd:TIGR01612 1658 FLESLKDQKKNIEDKKKELDELDSEIEKIEidvdqhkknyeigiiEKIKEIAIANK 1713
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
249-489 |
3.78e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.01 E-value: 3.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 249 ETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQvsAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKESLENM 328
Cdd:COG3206 164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFR--QKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEAR 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 329 MQRHEEEAHEKGKILSEQKAminamDSKIRSLEQRIVELSEanKLAANSSLFTQRN--MKAQEEMISELRQQkfyletqa 406
Cdd:COG3206 242 LAALRAQLGSGPDALPELLQ-----SPVIQQLRAQLAELEA--ELAELSARYTPNHpdVIALRAQIAALRAQ-------- 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 407 gkLEAQNRKLEEQLEkishqdhsdkSRLLELETRLREVSLEHEEQKLELKRqltelqlsLQERESQLTALQAARAALESQ 486
Cdd:COG3206 307 --LQQEAQRILASLE----------AELEALQAREASLQAQLAQLEARLAE--------LPELEAELRRLEREVEVAREL 366
|
...
gi 1039770412 487 LRQ 489
Cdd:COG3206 367 YES 369
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
5-741 |
3.95e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 45.33 E-value: 3.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 5 EEAMMEQEMTR--LHRRVSEVEAVLSQKEVELKASETQrslleqdLATYITECSSLKRSLEQARMEVsQEDDKALQLLHD 82
Cdd:PRK04863 361 EERLEEQNEVVeeADEQQEENEARAEAAEEEVDELKSQ-------LADYQQALDVQQTRAIQYQQAV-QALERAKQLCGL 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 83 IREQSRKLQEIKEqEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKAnecqhklmkAKDQGKPEV 162
Cdd:PRK04863 433 PDLTADNAEDWLE-EFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSE---------AWDVARELL 502
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 163 GEYSKlEKINAEQQlkiQELQEKLekavkasTEATELLQNIRQAkERAERELEKLHNR-EDSSEGIKKKLVEAEERRHSL 241
Cdd:PRK04863 503 RRLRE-QRHLAEQL---QQLRMRL-------SELEQRLRQQQRA-ERLLAEFCKRLGKnLDDEDELEQLQEELEARLESL 570
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 242 ----ENKVKRLETMERRENRLKDDIQ--TKSEQIQQMADKILE-LEEKHREAQVSAQHL----------EVHLKQKEQHY 304
Cdd:PRK04863 571 sesvSEARERRMALRQQLEQLQARIQrlAARAPAWLAAQDALArLREQSGEEFEDSQDVteymqqllerERELTVERDEL 650
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 305 EEKIKVLDNQIKK-DLADKESLENMMQRHEeeaHEKGKILSE---------------------QKAMINAMDSKIRSLEQ 362
Cdd:PRK04863 651 AARKQALDEEIERlSQPGGSEDPRLNALAE---RFGGVLLSEiyddvsledapyfsalygparHAIVVPDLSDAAEQLAG 727
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 363 R-----IVELSEANKLAANSSLFT-------------QRNM-------------KAQEEMISELRQQKFYLETQAGKLEA 411
Cdd:PRK04863 728 LedcpeDLYLIEGDPDSFDDSVFSveelekavvvkiaDRQWrysrfpevplfgrAAREKRIEQLRAEREELAERYATLSF 807
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 412 QNRKLEeqlekishqdhsdksRLLELETRLREVSL-----EHEEQKLELKRQltelqlSLQERESQLTALQAARAALESQ 486
Cdd:PRK04863 808 DVQKLQ---------------RLHQAFSRFIGSHLavafeADPEAELRQLNR------RRVELERALADHESQEQQQRSQ 866
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 487 LRQAKteleettaeaeEEIQALTAHRDEIQRKFDALRNSctVITDLEEQLNQLTEDNAELNNQNFYLSkQLDEasgandE 566
Cdd:PRK04863 867 LEQAK-----------EGLSALNRLLPRLNLLADETLAD--RVEEIREQLDEAEEAKRFVQQHGNALA-QLEP------I 926
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 567 IVQLRS---EVDHLRREITEREMQLTSQKQTMEALKTTCTML-----EEQVLDLE---ALNDELLEKERQWEAWRSVLGD 635
Cdd:PRK04863 927 VSVLQSdpeQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRahfsyEDAAEMLAknsDLNEKLRQRLEQAEQERTRARE 1006
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 636 EKSQFECRVRELQRMLDTEKQSRARADQRITESRQ-VVELAVK-EHKAEILA------LQQALKEQKLKAESlsdklndL 707
Cdd:PRK04863 1007 QLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQeLQDLGVPaDSGAEERArarrdeLHARLSANRSRRNQ-------L 1079
|
810 820 830
....*....|....*....|....*....|....*.
gi 1039770412 708 EKKHAMLEMNARSLQQKL-ETERELKQ-RLLEEQAK 741
Cdd:PRK04863 1080 EKQLTFCEAEMDNLTKKLrKLERDYHEmREQVVNAK 1115
|
|
| C1_Munc13-2-like |
cd20859 |
protein kinase C conserved region 1 (C1 domain) found in Munc13-2, Munc13-3 and similar ... |
925-979 |
4.09e-04 |
|
protein kinase C conserved region 1 (C1 domain) found in Munc13-2, Munc13-3 and similar proteins; Munc13-2, also called protein unc-13 homolog B (Unc13B), plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). Munc13-2 is essential for normal release probability at hippocampal mossy fiber synapses. Munc13-3 is almost exclusively expressed in the cerebellum. It acts as a tumor suppressor and plays a critical role in the formation of release sites with calcium channel nanodomains. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410409 Cd Length: 82 Bit Score: 40.82 E-value: 4.09e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 925 MHHNIPHRFNVGLNMRATKCAVCLDTV-HFGRQASKCLECQVMCHPKCSTCLPATC 979
Cdd:cd20859 14 ISCTTPHNFEVWTATTPTYCYECEGLLwGIARQGMRCSECGVKCHEKCQDLLNADC 69
|
|
| DUF4670 |
pfam15709 |
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ... |
59-222 |
4.19e-04 |
|
Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.
Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 44.94 E-value: 4.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 59 KRSLEQARMEVSQEDDKALQllHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLV----SARRRSDLYESELRESR 134
Cdd:pfam15709 345 MRRLEVERKRREQEEQRRLQ--QEQLERAEKMREELELEQQRRFEEIRLRKQRLEEERQrqeeEERKQRLQLQAAQERAR 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 135 LAAEEFKRKANECQHKlmkaKDQGKPEVGEYSKLEKINAEQQLKiqELQEKLekAVKASTEATELLQNIRQAKERAEREL 214
Cdd:pfam15709 423 QQQEEFRRKLQELQRK----KQQEEAERAEAEKQRQKELEMQLA--EEQKRL--MEMAEEERLEYQRQKQEAEEKARLEA 494
|
....*...
gi 1039770412 215 EKLHNRED 222
Cdd:pfam15709 495 EERRQKEE 502
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
652-845 |
4.24e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 45.01 E-value: 4.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 652 DTEKQSRARADQRITESRQVVELAVKE---HKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQ------ 722
Cdd:PHA02562 202 KNIEEQRKKNGENIARKQNKYDELVEEaktIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQkvikmy 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 723 ----------QKLETERELKQRLLEEQAKLQQQMDLQKNHIfrltQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEk 792
Cdd:PHA02562 282 ekggvcptctQQISEGPDRITKIKDKLKELQHSLEKLDTAI----DELEEIMDEFNEQSKKLLELKNKISTNKQSLITL- 356
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1039770412 793 vkmEGTISQQTKLIDFLQAkmDQPAKKKKVplqyNELKLALEKEKARCAELEE 845
Cdd:PHA02562 357 ---VDKAKKVKAAIEELQA--EFVDNAEEL----AKLQDELDKIVKTKSELVK 400
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
227-623 |
4.24e-04 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 44.84 E-value: 4.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 227 IKKKLVEAEE--RRHSLeNKVKRleTMERRENRLkDDIQTKSEQIQQMADKILELEEKHREAqvsAQHLEVH-------L 297
Cdd:pfam06160 65 IEELLFEAEElnDKYRF-KKAKK--ALDEIEELL-DDIEEDIKQILEELDELLESEEKNREE---VEELKDKyrelrktL 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 298 KQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHE-EEAHEkgkILSEQKAMINAMDSKIRSLEQRIVELseanklaan 376
Cdd:pfam06160 138 LANRFSYGPAIDELEKQLAEIEEEFSQFEELTESGDyLEARE---VLEKLEEETDALEELMEDIPPLYEEL--------- 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 377 sslftQRNMKAQ----EEMISELRQQKFYLETQagkleaqnrKLEEQLEKISHQDHSDKSRLLELEtrlrevsLEHEEQK 452
Cdd:pfam06160 206 -----KTELPDQleelKEGYREMEEEGYALEHL---------NVDKEIQQLEEQLEENLALLENLE-------LDEAEEA 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 453 LE-LKRQLTELQLSLqEREsqltalqaaraalesqlrqakteleettaeaeeeIQAltahRDEIQRKFDALRNSctvITD 531
Cdd:pfam06160 265 LEeIEERIDQLYDLL-EKE----------------------------------VDA----KKYVEKNLPEIEDY---LEH 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 532 LEEQLNQLTEDNAELnNQNFYLS-KQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVL 610
Cdd:pfam06160 303 AEEQNKELKEELERV-QQSYTLNeNELERVRGLEKQLEELEKRYDEIVERLEEKEVAYSELQEELEEILEQLEEIEEEQE 381
|
410
....*....|....
gi 1039770412 611 DL-EALNDelLEKE 623
Cdd:pfam06160 382 EFkESLQS--LRKD 393
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
18-486 |
4.73e-04 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 44.74 E-value: 4.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 18 RRVSEV-EAVLSQKEVELKasETQRSLLEQDLATYITECSSLKRSL-EQARMEVSQ-----EDDKALQLLHDIREQSRKL 90
Cdd:pfam07111 184 KRAGEAkQLAEAQKEAELL--RKQLSKTQEELEAQVTLVESLRKYVgEQVPPEVHSqtwelERQELLDTMQHLQEDRADL 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 91 QEIKEQeYQAQVEEMRLMMNQLEEDLVSARRRSDLYESEL-RESRLAAEEFKRKANECQHKLmKAKDqgkpevgeyskLE 169
Cdd:pfam07111 262 QATVEL-LQVRVQSLTHMLALQEEELTRKIQPSDSLEPEFpKKCRSLLNRWREKVFALMVQL-KAQD-----------LE 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 170 KINAEQQLKIQ--ELQEKlekaVKASTEATELLQNIRQAKErAERELEKLhnredSSEGIKKKLVEAEERRHSLENKVKR 247
Cdd:pfam07111 329 HRDSVKQLRGQvaELQEQ----VTSQSQEQAILQRALQDKA-AEVEVERM-----SAKGLQMELSRAQEARRRQQQQTAS 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 248 LETMER----RENRLKDDIQTKSEQIQQMADKILELEEK--------HREAQVSAQHLEV-HLKQKEQHYEEKIKVLDNQ 314
Cdd:pfam07111 399 AEEQLKfvvnAMSSTQIWLETTMTRVEQAVARIPSLSNRlsyavrkvHTIKGLMARKVALaQLRQESCPPPPPAPPVDAD 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 315 IKKDLadkESLENMMQRHEEEAHEKGKILSEQKAminamdskiRSLEQRIVELSEANKLAANsslFTQRNMKAQEEMISE 394
Cdd:pfam07111 479 LSLEL---EQLREERNRLDAELQLSAHLIQQEVG---------RAREQGEAERQQLSEVAQQ---LEQELQRAQESLASV 543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 395 LRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQLTELQLSL-------- 466
Cdd:pfam07111 544 GQQLEVARQGQQESTEEAASLRQELTQQQEIYGQALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLrqiqhrat 623
|
490 500
....*....|....*....|..
gi 1039770412 467 --QERESQLTALQAARAALESQ 486
Cdd:pfam07111 624 qeKERNQELRRLQDEARKEEGQ 645
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
11-330 |
5.69e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 44.63 E-value: 5.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 11 QEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKL 90
Cdd:TIGR04523 433 ETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKV 512
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 91 QEIKEQ--EYQAQVEEMRLMMNQLEEDLvsarrrSDLyESELRE--SRLAAEEFKRKANECQHKLMKAKDqgkpevgEYS 166
Cdd:TIGR04523 513 KDLTKKisSLKEKIEKLESEKKEKESKI------SDL-EDELNKddFELKKENLEKEIDEKNKEIEELKQ-------TQK 578
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 167 KLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHSLENKVK 246
Cdd:TIGR04523 579 SLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIR 658
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 247 rlETMERRENRLKDDIQTKSEQIQQMADKILELeEKHREAQVSAQHLEVHLKQKEQHYEEkikvldnqIKKDLAD----K 322
Cdd:TIGR04523 659 --NKWPEIIKKIKESKTKIDDIIELMKDWLKEL-SLHYKKYITRMIRIKDLPKLEEKYKE--------IEKELKKldefS 727
|
....*...
gi 1039770412 323 ESLENMMQ 330
Cdd:TIGR04523 728 KELENIIK 735
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
458-675 |
6.31e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.05 E-value: 6.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 458 QLTELQLSLQERESQLTALQAARAALESQLRQAKTEleettaeaeeeIQALTAHRDEIQRKFDALRNSctvITDLEEQLN 537
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEE-----------YNELQAELEALQAEIDKLQAE---IAEAEAEIE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 538 QLTEDNAELNNQNF---YLSKQLDEASGANDeIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEA 614
Cdd:COG3883 83 ERREELGERARALYrsgGSVSYLDVLLGSES-FSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770412 615 LNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELA 675
Cdd:COG3883 162 LKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
99-441 |
6.40e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.78 E-value: 6.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 99 QAQVEEMRLMMNQLEEDLVS---ARRRSDL--------YESELRESRLAAEEFKRKAN----ECQHKLMKAKDQGKPEVG 163
Cdd:pfam01576 691 EQQVEEMKTQLEELEDELQAtedAKLRLEVnmqalkaqFERDLQARDEQGEEKRRQLVkqvrELEAELEDERKQRAQAVA 770
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 164 EYSKLEkinaeqqLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKklvEAEERRHSLEN 243
Cdd:pfam01576 771 AKKKLE-------LDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSK---ESEKKLKNLEA 840
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 244 KVKRLETMERRENRLKDDIQTKSEQIQ------------------QMADKILELEEKHREAQVSAQHLEVHLKQKEQHYE 305
Cdd:pfam01576 841 ELLQLQEDLAASERARRQAQQERDELAdeiasgasgksalqdekrRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVE 920
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 306 EkikvLDNQIKKDLADKESLENMMQRHEEEAHE--------KGKILSEQKAMINAMDSKIRSLEQRIVElsEANKLAANS 377
Cdd:pfam01576 921 Q----LTTELAAERSTSQKSESARQQLERQNKElkaklqemEGTVKSKFKSSIAALEAKIAQLEEQLEQ--ESRERQAAN 994
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 378 SLFTQRNMKAQEEMI--------------------SELRQQKFYL---ETQAGKLEAQNRKLEEQLEKISHQDHSDKSRL 434
Cdd:pfam01576 995 KLVRRTEKKLKEVLLqvederrhadqykdqaekgnSRMKQLKRQLeeaEEEASRANAARRKLQRELDDATESNESMNREV 1074
|
....*..
gi 1039770412 435 LELETRL 441
Cdd:pfam01576 1075 STLKSKL 1081
|
|
| C1_dGM13116p-like |
cd20831 |
protein kinase C conserved region 1 (C1 domain) found in Drosophila melanogaster GM13116p and ... |
942-979 |
6.74e-04 |
|
protein kinase C conserved region 1 (C1 domain) found in Drosophila melanogaster GM13116p and similar proteins; This group contains uncharacterized proteins including Drosophila melanogaster GM13116p and Caenorhabditis elegans hypothetical protein R11G1.4, both of which contain C2 (a calcium-binding domain) and C1 domains. This model describes the C1 domain, a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410381 Cd Length: 58 Bit Score: 39.25 E-value: 6.74e-04
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1039770412 942 TKCAVCLDTV--HFGRQASKCLECQVMCHPKCSTCLPATC 979
Cdd:cd20831 17 PSCAVCNKLIpgRFGKQGYQCRDCGLICHKRCHVKVETHC 56
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
572-705 |
6.92e-04 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 43.80 E-value: 6.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 572 SEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELlekerqwEAWRSVLGDEKSQFECRVRELQRML 651
Cdd:PRK09039 53 SALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRL-------QALLAELAGAGAAAEGRAGELAQEL 125
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039770412 652 DTEKQSRARADQRITE-SRQVVELavkehKAEILALQQAL-------KEQKLKAESLSDKLN 705
Cdd:PRK09039 126 DSEKQVSARALAQVELlNQQIAAL-----RRQLAALEAALdasekrdRESQAKIADLGRRLN 182
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
83-317 |
7.63e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 44.23 E-value: 7.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 83 IREQSrklQEIKEQEYQAQVEEMRLMM---NQLEEDLVSARRRSDL---YESELREsrlaAEEFKRKANECQHKLMK-AK 155
Cdd:PHA02562 176 IRELN---QQIQTLDMKIDHIQQQIKTynkNIEEQRKKNGENIARKqnkYDELVEE----AKTIKAEIEELTDELLNlVM 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 156 DQGKPEvgeySKLEKINAEQ---QLKIQELQeKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLV 232
Cdd:PHA02562 249 DIEDPS----AALNKLNTAAakiKSKIEQFQ-KVIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAID 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 233 EAEERRHSLENKVKRLetmerreNRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLD 312
Cdd:PHA02562 324 ELEEIMDEFNEQSKKL-------LELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKS 396
|
....*
gi 1039770412 313 NQIKK 317
Cdd:PHA02562 397 ELVKE 401
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
514-814 |
8.17e-04 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 44.18 E-value: 8.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 514 EIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFY----LSKQLDEasgandEIVQLRSEVDHLRREITERE---- 585
Cdd:COG5185 233 EALKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGenaeSSKRLNE------NANNLIKQFENTKEKIAEYTksid 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 586 -----MQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGDEKSQF--ECRVRELQRMLDTEKQSR 658
Cdd:COG5185 307 ikkatESLEEQLAAAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIvgEVELSKSSEELDSFKDTI 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 659 ARADQRITESRQVVELAVKEHKAeilALQQALKEQKLKAESLSDKLNDLEKKhamlemNARSLQQKLETERELKQRLLEE 738
Cdd:COG5185 387 ESTKESLDEIPQNQRGYAQEILA---TLEDTLKAADRQIEELQRQIEQATSS------NEEVSKLLNELISELNKVMREA 457
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 739 QAKLQQQMDLQKNHIFRltqGLQEALDRADLlktERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMD 814
Cdd:COG5185 458 DEESQSRLEEAYDEINR---SVRSKKEDLNE---ELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLK 527
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
59-485 |
9.03e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 43.73 E-value: 9.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 59 KRSLEQARMEVSQEDD----KALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEdlvsarrrsdlyesELRESR 134
Cdd:pfam07888 28 RAELLQNRLEECLQERaellQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKE--------------ELRQSR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 135 LAAEEFKRKANEcqhklmkAKDQGKPEVGEYSKLEKINAEQQLKIQELQEKLEK-AVKASTEATELlqniRQAKERAERE 213
Cdd:pfam07888 94 EKHEELEEKYKE-------LSASSEELSEEKDALLAQRAAHEARIRELEEDIKTlTQRVLERETEL----ERMKERAKKA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 214 LEKLHNREDSSEGIKKKLVEAEERRHSLENKVKrletmerrenRLKDDIQTKSEQIQQMADKILELEEKHREAQvsaqhl 293
Cdd:pfam07888 163 GAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ----------ELRNSLAQRDTQVLQLQDTITTLTQKLTTAH------ 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 294 evhlkQKEQHYEekikvldnQIKKDLADKESLENMMQRHEEeahekgKILSEQKAMINAMDSKIRSLEQRIVELSEANKL 373
Cdd:pfam07888 227 -----RKEAENE--------ALLEELRSLQERLNASERKVE------GLGEELSSMAAQRDRTQAELHQARLQAAQLTLQ 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 374 AANSSLF--------------TQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQL--EKISH--QDHSDKSRLL 435
Cdd:pfam07888 288 LADASLAlregrarwaqeretLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELgrEKDCNrvQLSESRRELQ 367
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 1039770412 436 ELETRLReVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALES 485
Cdd:pfam07888 368 ELKASLR-VAQKEKEQLQAEKQELLEYIRQLEQRLETVADAKWSEAALTS 416
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
552-787 |
9.22e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.85 E-value: 9.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 552 YLSKQLDEASGANDEIVQ-LRSEVDHLRREITEREMQLTS--QKQTMEALKTTCTMLEEQVLDLE----ALNDELLEKER 624
Cdd:COG3206 161 YLEQNLELRREEARKALEfLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELEsqlaEARAELAEAEA 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 625 QWEAWRSVLGDEKSQF-----ECRVRELQRMLDTEKQSRARADQRITE-SRQVVELavkehKAEILALQQALKEQKLKAe 698
Cdd:COG3206 241 RLAALRAQLGSGPDALpellqSPVIQQLRAQLAELEAELAELSARYTPnHPDVIAL-----RAQIAALRAQLQQEAQRI- 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 699 slsdkLNDLEKKHAMLEMNARSLQQKLEterELKQRLLEEQAKLQQQMDLQKNhIFRLTQGLQEALDRADLLKTERSdle 778
Cdd:COG3206 315 -----LASLEAELEALQAREASLQAQLA---QLEARLAELPELEAELRRLERE-VEVARELYESLLQRLEEARLAEA--- 382
|
....*....
gi 1039770412 779 YQLENIQVL 787
Cdd:COG3206 383 LTVGNVRVI 391
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
163-257 |
9.53e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 43.69 E-value: 9.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 163 GEYSKLEKINAEQQLKIQELQEKLEKAVKAsteatellqniRQAKERAERELEKLHNREDSsegIKKKLVEAEERRHSLE 242
Cdd:COG2433 427 AEVEELEAELEEKDERIERLERELSEARSE-----------ERREIRKDREISRLDREIER---LERELEEERERIEELK 492
|
90
....*....|....*
gi 1039770412 243 NKVKRLETMERRENR 257
Cdd:COG2433 493 RKLERLKELWKLEHS 507
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
54-334 |
1.07e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 43.69 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 54 ECSSLKRSLEQARMEVSQEDDKALQllhdirEQSRKLQEIKEQEYQAQVEEMRLM--MNQLEEDLVSARRRSDLYESELR 131
Cdd:PLN03229 437 EVEKLKEQILKAKESSSKPSELALN------EMIEKLKKEIDLEYTEAVIAMGLQerLENLREEFSKANSQDQLMHPVLM 510
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 132 ESrlaaeefkrkanecQHKLMKAKDQGKPEVGEY----SKLEKINA--------EQQLKIQELQEKLEKAVKASTEATEL 199
Cdd:PLN03229 511 EK--------------IEKLKDEFNKRLSRAPNYlslkYKLDMLNEfsrakalsEKKSKAEKLKAEINKKFKEVMDRPEI 576
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 200 LQNIRQAKerAERELEKLHNREDSSEGIKKKLVEAEE----------RRHSLENKVKRLETMERRENRLKDDIQTKSEQI 269
Cdd:PLN03229 577 KEKMEALK--AEVASSGASSGDELDDDLKEKVEKMKKeielelagvlKSMGLEVIGVTKKNKDTAEQTPPPNLQEKIESL 654
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770412 270 QQMADKILELEEKHREAQVSAQHLEVHL----KQKEQHYEEKIKVLDNQIKKDLADKESLENMMQRHEE 334
Cdd:PLN03229 655 NEEINKKIERVIRSSDLKSKIELLKLEVakasKTPDVTEKEKIEALEQQIKQKIAEALNSSELKEKFEE 723
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
83-400 |
1.10e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 43.35 E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 83 IREQSRKLQEIKEQ--EYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKLMKAKDQGKP 160
Cdd:COG4372 33 LRKALFELDKLQEEleQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 161 EVGEYSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEERRHS 240
Cdd:COG4372 113 LQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEA 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 241 LENKVKRLETMERRENRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLA 320
Cdd:COG4372 193 NRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKD 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 321 DKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKF 400
Cdd:COG4372 273 TEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLD 352
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
330-750 |
1.14e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 43.67 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 330 QRHEEEAHEKGKILSEQKAMINAMDS------KIRSLEQRIVELSEANKLAANSSLFTQRNMKAQ-EEMISELRQQKFYL 402
Cdd:pfam12128 234 AGIMKIRPEFTKLQQEFNTLESAELRlshlhfGYKSDETLIASRQEERQETSAELNQLLRTLDDQwKEKRDELNGELSAA 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 403 ETQAGKLEAQNRKLEEQLEKISHQD----HSDKSRLLELETRLREVSLEHE---------EQKLELKRQLTELQL----- 464
Cdd:pfam12128 314 DAAVAKDRSELEALEDQHGAFLDADietaAADQEQLPSWQSELENLEERLKaltgkhqdvTAKYNRRRSKIKEQNnrdia 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 465 --------SLQERESQLTALQAARAALESQLRQAKTeleettaeaeeeiQALTAHRDEIQRKFDALRNSCTVITDL---E 533
Cdd:pfam12128 394 gikdklakIREARDRQLAVAEDDLQALESELREQLE-------------AGKLEFNEEEYRLKSRLGELKLRLNQAtatP 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 534 EQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTC-----TMLE-- 606
Cdd:pfam12128 461 ELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqagTLLHfl 540
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 607 -------EQVLDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVReLQRM-----LDTEKQSRARADQritesrqvvel 674
Cdd:pfam12128 541 rkeapdwEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLD-LKRIdvpewAASEEELRERLDK----------- 608
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 675 aVKEhkaeilALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQK 750
Cdd:pfam12128 609 -AEE------ALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERK 677
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
556-865 |
1.25e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 43.35 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 556 QLDEASGANDEIVQLRSEVDHLRREITEREMqltsqKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSVLGD 635
Cdd:pfam07888 48 QAQEAANRQREKEKERYKRDREQWERQRREL-----ESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLA 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 636 EKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAV---KEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHA 712
Cdd:pfam07888 123 QRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGaqrKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLA 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 713 MLEMNARSLQQKLETereLKQRLLEEQAKlQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEK 792
Cdd:pfam07888 203 QRDTQVLQLQDTITT---LTQKLTTAHRK-EAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQAR 278
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770412 793 VKMEGTISQQTKLIDFLQAKMDQPAKKKKVPLQYNEL-KLALEKEKARCAELEEALQKTRIELRSAREEAAHRK 865
Cdd:pfam07888 279 LQAAQLTLQLADASLALREGRARWAQERETLQQSAEAdKDRIEKLSAELQRLEERLQEERMEREKLEVELGREK 352
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
169-369 |
1.27e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 43.38 E-value: 1.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 169 EKINAEQQLKIQELQEKLEKAV---KASTEATELLQNIRQAKEraERELEKLHNREDSS-EGIKKKLVEAEERRHSLENK 244
Cdd:PRK05771 38 EELSNERLRKLRSLLTKLSEALdklRSYLPKLNPLREEKKKVS--VKSLEELIKDVEEElEKIEKEIKELEEEISELENE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 245 VKRLETMERRENRLKD-DIqtkseqiqqmaDKILELEEKH---REAQVSAQHLEVHLKQKEQHYEEKIKVLDN------- 313
Cdd:PRK05771 116 IKELEQEIERLEPWGNfDL-----------DLSLLLGFKYvsvFVGTVPEDKLEELKLESDVENVEYISTDKGyvyvvvv 184
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039770412 314 QIKKDLADKESLenmMQRHE---EEAHEKGK---ILSEQKAMINAMDSKIRSLEQRIVELSE 369
Cdd:PRK05771 185 VLKELSDEVEEE---LKKLGferLELEEEGTpseLIREIKEELEEIEKERESLLEELKELAK 243
|
|
| C1_MRCK |
cd20809 |
protein kinase C conserved region 1 (C1 domain) found in the Myotonic dystrophy kinase-related ... |
931-982 |
1.37e-03 |
|
protein kinase C conserved region 1 (C1 domain) found in the Myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) family; MRCK is thought to be a coincidence detector of signaling by the small GTPase Cdc42 and phosphoinositides. MRCK/Cdc42 signaling mediates myosin-dependent cell motility. MRCK has been shown to promote cytoskeletal reorganization, which affects many biological processes. Three isoforms of MRCK are known, named alpha, beta and gamma. MRCKgamma is expressed in heart and skeletal muscles, unlike MRCKalpha and MRCKbeta, which are expressed ubiquitously. MRCK consists of a serine/threonine kinase domain, a cysteine rich (C1) region, a PH domain and a p21 binding motif. This model corresponds to C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410359 Cd Length: 53 Bit Score: 38.41 E-value: 1.37e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1039770412 931 HRFNVGLNMRATKCAVClDTVHFG--RQASKCLECQVMCHPKCSTCLPATCGLP 982
Cdd:cd20809 1 HKFIVRTFSTPTKCNHC-TSLMVGlvRQGLVCEVCGYACHVSCADKAPQVCPVP 53
|
|
| C1_MRCKalpha |
cd20864 |
protein kinase C conserved region 1 (C1 domain) found in myotonic dystrophy kinase-related ... |
931-984 |
1.37e-03 |
|
protein kinase C conserved region 1 (C1 domain) found in myotonic dystrophy kinase-related Cdc42-binding kinase alpha (MRCK alpha) and similar proteins; MRCK alpha, also called Cdc42-binding protein kinase alpha, DMPK-like alpha, or myotonic dystrophy protein kinase-like alpha, is a serine/threonine-protein kinase expressed ubiquitously in many tissues. It plays a role in the regulation of peripheral actin reorganization and neurite outgrowth. It may also play a role in the transferrin iron uptake pathway. MRCK alpha is an important downstream effector of Cdc42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410414 Cd Length: 60 Bit Score: 38.46 E-value: 1.37e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1039770412 931 HRFNVGLNMRATKCAVCLD-TVHFGRQASKCLECQVMCHPKCSTCLPATCGLPAE 984
Cdd:cd20864 3 HQFVVKSFTTPTKCNQCTSlMVGLIRQGCTCEVCGFSCHVTCADKAPSVCPIPPE 57
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
258-426 |
1.38e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 43.23 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 258 LKDDIQTKSEQIQQMADKIleLEEKHREAqvsaqhlEVHLKQKEQHYEEKIKVLDNQIKKDLADKeslENMMQRHEEEAH 337
Cdd:PRK12704 25 RKKIAEAKIKEAEEEAKRI--LEEAKKEA-------EAIKKEALLEAKEEIHKLRNEFEKELRER---RNELQKLEKRLL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 338 EKGKILSEQKAMINAMDSKIRSLEQRIVELseanklaansslftQRNMKAQEEMISELR-QQKFYLETQAG--KLEAQNR 414
Cdd:PRK12704 93 QKEENLDRKLELLEKREEELEKKEKELEQK--------------QQELEKKEEELEELIeEQLQELERISGltAEEAKEI 158
|
170
....*....|..
gi 1039770412 415 KLEEQLEKISHQ 426
Cdd:PRK12704 159 LLEKVEEEARHE 170
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
529-709 |
1.39e-03 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 43.09 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 529 ITDLEEQLNQLTEDNAELNnqnfylskqlDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQ 608
Cdd:pfam05667 337 LEELQEQLEDLESSIQELE----------KEIKKLESSIKQVEEELEELKEQNEELEKQYKVKKKTLDLLPDAEENIAKL 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 609 VLDLEALNDELLEKERQWEAWRSVLGDEksqfecrVRELqrmldtekqsRARADQRITESRQVVElAVKEHKAEIlalQQ 688
Cdd:pfam05667 407 QALVDASAQRLVELAGQWEKHRVPLIEE-------YRAL----------KEAKSNKEDESQRKLE-EIKELREKI---KE 465
|
170 180
....*....|....*....|.
gi 1039770412 689 ALKEQKLKAESLSDKLNDLEK 709
Cdd:pfam05667 466 VAEEAKQKEELYKQLVAEYER 486
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
571-906 |
1.46e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.19 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 571 RSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEawRSVLGDEKSQFE--------- 641
Cdd:pfam17380 295 KMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELE--RIRQEERKRELErirqeeiam 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 642 --CRVRELQRMLDTEKQSRARADQRITESRQvVELAVKEHkaeilalQQALKEQKLKAESLSDKlndlekkhamlEMNAR 719
Cdd:pfam17380 373 eiSRMRELERLQMERQQKNERVRQELEAARK-VKILEEER-------QRKIQQQKVEMEQIRAE-----------QEEAR 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 720 SLQ-QKLETERELK-QRLLEEQAKLQQQMDlqknhifRLTQglQEALDRADLLKTERSDLEYQLENIQVLYSHEKvkmeg 797
Cdd:pfam17380 434 QREvRRLEEERAREmERVRLEEQERQQQVE-------RLRQ--QEEERKRKKLELEKEKRDRKRAEEQRRKILEK----- 499
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 798 tisqqtKLIDFLQAKMDQPAKKKKVPLQYNELKLAL-EKEKARCAELEEALQKTRIELRSAREEAahRKATDHpHPSTPA 876
Cdd:pfam17380 500 ------ELEERKQAMIEEERKRKLLEKEMEERQKAIyEEERRREAEEERRKQQEMEERRRIQEQM--RKATEE-RSRLEA 570
|
330 340 350
....*....|....*....|....*....|
gi 1039770412 877 TARQQIAMSAIVRSpEHQPSAMSLLAPPSS 906
Cdd:pfam17380 571 MEREREMMRQIVES-EKARAEYEATTPITT 599
|
|
| C1_TNS1_v |
cd20888 |
protein kinase C conserved region 1 (C1 domain) found in tensin-1 (TNS1) variant and similar ... |
931-978 |
1.54e-03 |
|
protein kinase C conserved region 1 (C1 domain) found in tensin-1 (TNS1) variant and similar proteins; Tensin-1 (TNS1) plays a role in fibrillar adhesion formation. It may be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton. This model corresponds to the C1 domain found in TNS1 variant. Typical TNS1 does not contain C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410438 Cd Length: 57 Bit Score: 38.31 E-value: 1.54e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1039770412 931 HRFNVGLNMRATKCAVCLDTVhfGRQASKCLECQVMCHPKC-----STCLPAT 978
Cdd:cd20888 6 HTFKVKTFKKVKSCGICKQAI--TREGSTCRVCKLSCHKKCeakvaTPCVPAV 56
|
|
| CCDC73 |
pfam15818 |
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ... |
85-313 |
1.63e-03 |
|
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.
Pssm-ID: 464893 [Multi-domain] Cd Length: 1048 Bit Score: 43.40 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 85 EQSRKLQEIKEQEYQAQVEEMR----LMMNQ----------LEEDLVSA----RRRSDLYESELRESRLAAEEFKRKANE 146
Cdd:pfam15818 119 EQKLQLHLLAKEDHHKQLNEIEkyyaTITGQfglvkenhgkLEQNVQEAiqlnKRLSALNKKQESEICSLKKELKKVTSD 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 147 cqhkLMKAKDQGKPEVGEysklEKIN-AEQQLKIQELQEKL----EKAVKASTEAT-----------------ELLQNIR 204
Cdd:pfam15818 199 ----LIKSKVTCQYKMGE----ENINlTIKEQKFQELQERLnmelELNKKINEEIThiqeekqdiiisfqhmqQLLQQQT 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 205 QAKERAEREL----EKLHNREDSSEGIKKKLVEAEERRHSLENKvkrletMERRENRLKDDIQTKSEQIQQMADKILELE 280
Cdd:pfam15818 271 QANTEMEAELkalkENNQTLERDNELQREKVKENEEKFLNLQNE------HEKALGTWKKHVEELNGEINEIKNELSSLK 344
|
250 260 270
....*....|....*....|....*....|...
gi 1039770412 281 EKHREAQvsaqhlEVHLKQKEQHYEEKIKVLDN 313
Cdd:pfam15818 345 ETHIKLQ------EHYNKLCNQKKFEEDKKFQN 371
|
|
| Stathmin |
pfam00836 |
Stathmin family; The Stathmin family of proteins play an important role in the regulation of ... |
219-306 |
1.72e-03 |
|
Stathmin family; The Stathmin family of proteins play an important role in the regulation of the microtubule cytoskeleton. They regulate microtubule dynamics by promoting depolymerization of microtubules and/or preventing polymerization of tubulin heterodimers.
Pssm-ID: 459956 [Multi-domain] Cd Length: 136 Bit Score: 40.41 E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 219 NREDSSEGIKKKLVEAEERRHSLE-NKVKRLETMERRENRLKDDIQTKSEQIQQMADKIL----ELEEKHREAQVSAqhL 293
Cdd:pfam00836 39 KKDSSLEEIQKKLEAAEERRKSLEaQKLKQLAEKREKEEEALQKADEENNNFSKMAEEKLkqkmEAYKENREAQIAA--L 116
|
90
....*....|...
gi 1039770412 294 EVHLKQKEQHYEE 306
Cdd:pfam00836 117 KEKLKEKEKHVEE 129
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
36-257 |
1.83e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.44 E-value: 1.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 36 ASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQ--EYQAQVEEMRLMMNQLE 113
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQElaALEAELAELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 114 EDLvsaRRRSDLYESELRE----SRLAAEEFKRKANECQHKLMKAKDQGKPEVGEYSKLEKINAEQQL---KIQELQEKL 186
Cdd:COG4942 97 AEL---EAQKEELAELLRAlyrlGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAElaaLRAELEAER 173
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039770412 187 EKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEgikKKLVEAEERRHSLENKVKRLETMERRENR 257
Cdd:COG4942 174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELA---AELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| C1_ScPKC1-like_rpt1 |
cd20822 |
first protein kinase C conserved region 1 (C1 domain) found in Saccharomyces cerevisiae ... |
926-979 |
1.84e-03 |
|
first protein kinase C conserved region 1 (C1 domain) found in Saccharomyces cerevisiae protein kinase C-like 1 (ScPKC1) and similar proteins; ScPKC1 is required for cell growth and for the G2 to M transition of the cell division cycle. It mediates a protein kinase cascade, activating BCK1 which itself activates MKK1/MKK2. The family also includes Schizosaccharomyces pombe PKC1 and PKC2, which are involved in the control of cell shape and act as targets of the inhibitor staurosporine. Members of this family contain two copies of the C1 domain. This model corresponds to the first one. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410372 Cd Length: 52 Bit Score: 38.04 E-value: 1.84e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1039770412 926 HHNIPHRF-NVglnmraTKCAVCLDtvHFGRQASKCLECQVMCHPKCSTCLPATC 979
Cdd:cd20822 3 HKFVQKQFyQI------MRCAVCGE--FLVNAGYQCEDCKYTCHKKCYEKVVTKC 49
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
247-546 |
1.97e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 42.69 E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 247 RLETMERREnRLKD--DIQTKSEqiqqMaDKILEleEKHREAQVSAQHLEV---HLKQKEQHYEEKIKVLDNQIKKDLAD 321
Cdd:PHA02562 146 QLSAPARRK-LVEDllDISVLSE----M-DKLNK--DKIRELNQQIQTLDMkidHIQQQIKTYNKNIEEQRKKNGENIAR 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 322 KEsleNMMQRHEEEAhekgkilseqkamiNAMDSKIRSLEQRIVELS-EANKLAANSSLFTQRNMKAQEEMISELRQQKF 400
Cdd:PHA02562 218 KQ---NKYDELVEEA--------------KTIKAEIEELTDELLNLVmDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKM 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 401 YLETQAGKLEAQNrkLEEQLEKIShqdhSDKSRLLELETRLREVSlEHEEQKLELKRQLTELQLSLQERESQLTALQAAR 480
Cdd:PHA02562 281 YEKGGVCPTCTQQ--ISEGPDRIT----KIKDKLKELQHSLEKLD-TAIDELEEIMDEFNEQSKKLLELKNKISTNKQSL 353
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 481 AALESQLRQAKteleettaeaeeeiqaltahrDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAEL 546
Cdd:PHA02562 354 ITLVDKAKKVK---------------------AAIEELQAEFVDNAEELAKLQDELDKIVKTKSEL 398
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
170-491 |
2.11e-03 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 42.75 E-value: 2.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 170 KINAEQQLK-IQELQEKLEKAVKASTEATELLQNIRQAKERAEReLEKLhnrEDSSEGIKKKL---------VEAEERRH 239
Cdd:pfam05622 86 RIKCEELEKeVLELQHRNEELTSLAEEAQALKDEMDILRESSDK-VKKL---EATVETYKKKLedlgdlrrqVKLLEERN 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 240 S--LENKVKrLETMERRENRLKDDIQTKSEQIQqmadkilELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKK 317
Cdd:pfam05622 162 AeyMQRTLQ-LEEELKKANALRGQLETYKRQVQ-------ELHGKLSEESKKADKLEFEYKKLEEKLEALQKEKERLIIE 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 318 DLADKESLENM--MQRHEEEAHEKGKILSEQKAMINAMDSKIRSLE--QRIVELSEANKLaansslFTQRNMKAQEEMIS 393
Cdd:pfam05622 234 RDTLRETNEELrcAQLQQAELSQADALLSPSSDPGDNLAAEIMPAEirEKLIRLQHENKM------LRLGQEGSYRERLT 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 394 ELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQdhsdksrLLELETRLREVSlEHEEQKLELKRQLTELQLSLQERESQL 473
Cdd:pfam05622 308 ELQQLLEDANRRKNELETQNRLANQRILELQQQ-------VEELQKALQEQG-SKAEDSSLLKQKLEEHLEKLHEAQSEL 379
|
330 340
....*....|....*....|..
gi 1039770412 474 TALQAARAALE----SQLRQAK 491
Cdd:pfam05622 380 QKKKEQIEELEpkqdSNLAQKI 401
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
431-794 |
2.18e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.20 E-value: 2.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 431 KSRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTA 510
Cdd:COG4372 5 GEKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 511 HRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEasgANDEIVQLRSEVDHLRREITEREMQLTS 590
Cdd:COG4372 85 LNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQ---LEAQIAELQSEIAEREEELKELEEQLES 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 591 QKQTMEALKTTCTMLEEQVLDlEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQ 670
Cdd:COG4372 162 LQEELAALEQELQALSEAEAE-QALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 671 VVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEmNARSLQQKLETERELKQRLLEEQAKLQQQMDLQK 750
Cdd:COG4372 241 ALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALEL-EALEEAALELKLLALLLNLAALSLIGALEDALLA 319
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1039770412 751 NHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVK 794
Cdd:COG4372 320 ALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKGA 363
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
10-335 |
2.20e-03 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 42.69 E-value: 2.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 10 EQEMTRLHRRVSEVEAVLSQKEvelKASETQRsllEQDLATYITEC-SSLKRSLEQARMEVSQEDdkaLQLLHDIREQSR 88
Cdd:NF033838 131 KKDTLEPGKKVAEATKKVEEAE---KKAKDQK---EEDRRNYPTNTyKTLELEIAESDVEVKKAE---LELVKEEAKEPR 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 89 KLQEIKEQEY-----QAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEE-------FKRKANECQHKLMKAKD 156
Cdd:NF033838 202 DEEKIKQAKAkveskKAEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEqdkpkrrAKRGVLGEPATPDKKEN 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 157 QGK---PEVGEYS------KLEKINAEQQLKIQELQEKLEK----------AVKASTEATELLQNIRQAKErAERELEKL 217
Cdd:NF033838 282 DAKssdSSVGEETlpspslKPEKKVAEAEKKVEEAKKKAKDqkeedrrnypTNTYKTLELEIAESDVKVKE-AELELVKE 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 218 HNREDSSEgikKKLVEAEERRHSLENKVKRLEtmerrenRLKDDIQTKSEQIQQMADKILELEEKHREAQVSAQHLEVhl 297
Cdd:NF033838 361 EAKEPRNE---EKIKQAKAKVESKKAEATRLE-------KIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQP-- 428
|
330 340 350
....*....|....*....|....*....|....*...
gi 1039770412 298 kQKEQHYEEKIKVLDNQIKKDlaDKESLENMMQRHEEE 335
Cdd:NF033838 429 -EKPAPKPEKPAEQPKAEKPA--DQQAEEDYARRSEEE 463
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
510-710 |
2.41e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 42.31 E-value: 2.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 510 AHRDEIQRKFDALRNSctvITDLEEQLNQLTEDNAELNnqnfylsKQLDEASGA----NDEIVQLRSEVDHLRREITERE 585
Cdd:PHA02562 213 ENIARKQNKYDELVEE---AKTIKAEIEELTDELLNLV-------MDIEDPSAAlnklNTAAAKIKSKIEQFQKVIKMYE 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 586 ---------MQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAWRSvlgdeksqfecRVRELQRMLDTEKQ 656
Cdd:PHA02562 283 kggvcptctQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSK-----------KLLELKNKISTNKQ 351
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1039770412 657 SRARADQRITESRQVVELAVKE---HKAEILALQQALKEqklkaesLSDKLNDLEKK 710
Cdd:PHA02562 352 SLITLVDKAKKVKAAIEELQAEfvdNAEELAKLQDELDK-------IVKTKSELVKE 401
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
331-744 |
2.44e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 42.64 E-value: 2.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 331 RHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELS-EANKLAANSSLFTQRNMKAQEE---MISELRQQKfYLETQA 406
Cdd:PRK04863 276 RHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMArELAELNEAESDLEQDYQAASDHlnlVQTALRQQE-KIERYQ 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 407 GKLEAQNRKLEEQLEKISHQDhsdkSRLLELETRLREVslehEEQKLELKRQLTELQLSLQERESQLTALQAARAALESq 486
Cdd:PRK04863 355 ADLEELEERLEEQNEVVEEAD----EQQEENEARAEAA----EEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALER- 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 487 LRQAKTELEETTAEAEEEIQALTAHRDEIQrkfDALRnsctvitDLEEQLNqLTEDNAELNNQNFYLSKQL-------DE 559
Cdd:PRK04863 426 AKQLCGLPDLTADNAEDWLEEFQAKEQEAT---EELL-------SLEQKLS-VAQAAHSQFEQAYQLVRKIagevsrsEA 494
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 560 ASGANDEIVQLRSEVDH------LRREITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQWEAwrsvL 633
Cdd:PRK04863 495 WDVARELLRRLREQRHLaeqlqqLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLES----L 570
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 634 GDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVElavkehkaeilALQQaLKEQKLKAESLSDKLNDLEKKHAM 713
Cdd:PRK04863 571 SESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQD-----------ALAR-LREQSGEEFEDSQDVTEYMQQLLE 638
|
410 420 430
....*....|....*....|....*....|.
gi 1039770412 714 LEmnaRSLQQKLETERELKQRLLEEQAKLQQ 744
Cdd:PRK04863 639 RE---RELTVERDELAARKQALDEEIERLSQ 666
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
37-236 |
2.56e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.12 E-value: 2.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 37 SETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQ--EYQAQVEEMRlmmNQLEE 114
Cdd:COG3883 14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEiaEAEAEIEERR---EELGE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 115 DLVSARR--RSDLYESELRESRLAAEEFKR-----KANECQHKLMKAKDQGKPEVGEY-SKLEKINAEQQLKIQELQEKL 186
Cdd:COG3883 91 RARALYRsgGSVSYLDVLLGSESFSDFLDRlsalsKIADADADLLEELKADKAELEAKkAELEAKLAELEALKAELEAAK 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1039770412 187 EKAVKASTEATELLQNIRQAKERAERELEKLHNREDSSEGIKKKLVEAEE 236
Cdd:COG3883 171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
384-855 |
2.86e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 42.40 E-value: 2.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 384 NMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLELK------- 456
Cdd:pfam05483 72 NSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKdlikenn 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 457 --RQLTELQLSLQERESQLTA-------------------LQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEI 515
Cdd:pfam05483 152 atRHLCNLLKETCARSAEKTKkyeyereetrqvymdlnnnIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEY 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 516 QRKFDALRNSCTVItdleeqLNQLTEDNAELNNQNFYLSK------QLDEASGANDE-IVQLRSEVDHLRREITEREMQL 588
Cdd:pfam05483 232 KKEINDKEKQVSLL------LIQITEKENKMKDLTFLLEEsrdkanQLEEKTKLQDEnLKELIEKKDHLTKELEDIKMSL 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 589 TSQKQTMEAL--------KTTCTMLEEQVLDLEALNDE-------LLEKERQWEAWRSVLGDEKSQFECRVRELqRMLDT 653
Cdd:pfam05483 306 QRSMSTQKALeedlqiatKTICQLTEEKEAQMEELNKAkaahsfvVTEFEATTCSLEELLRTEQQRLEKNEDQL-KIITM 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 654 EKQSRARADQRITESRQVVELAVKEHKaEILALQQALKEQKLKAESLSDKLNDLEKKHAML----EMNARSLQQKLETER 729
Cdd:pfam05483 385 ELQKKSSELEEMTKFKNNKEVELEELK-KILAEDEKLLDEKKQFEKIAEELKGKEQELIFLlqarEKEIHDLEIQLTAIK 463
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 730 ELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDF- 808
Cdd:pfam05483 464 TSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKe 543
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 1039770412 809 LQAKMDQPAKKKKVPLQYNELKLALEKEKARCAELEEALQKTRIELR 855
Cdd:pfam05483 544 MNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMK 590
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
10-217 |
2.87e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 2.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 10 EQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQ---------DLATYITECSS-----------------LKRSLE 63
Cdd:COG4913 616 EAELAELEEELAEAEERLEALEAELDALQERREALQRlaeyswdeiDVASAEREIAEleaelerldassddlaaLEEQLE 695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 64 QARMEVSQEDDKALQLLHDIREQSRKLQEIKEQ--EYQAQVEEMRLMMNQLEEDLVSARRRS---DLYESELRE---SRL 135
Cdd:COG4913 696 ELEAELEELEEELDELKGEIGRLEKELEQAEEEldELQDRLEAAEDLARLELRALLEERFAAalgDAVERELREnleERI 775
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 136 AAEefKRKANECQHKLMKAKDQGKPE--------------VGEY-SKLEKINAEqqlKIQELQEKLEKAVKASTEA--TE 198
Cdd:COG4913 776 DAL--RARLNRAEEELERAMRAFNREwpaetadldadlesLPEYlALLDRLEED---GLPEYEERFKELLNENSIEfvAD 850
|
250
....*....|....*....
gi 1039770412 199 LLQNIRQAKERAERELEKL 217
Cdd:COG4913 851 LLSKLRRAIREIKERIDPL 869
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
102-242 |
2.96e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 42.51 E-value: 2.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 102 VEEMRLMMNQLEEDLvsarrrSDLYESeLRESRLAAEEfkrKANECQHKLMKAKDQgKPEVGEysKLEKINAEQQLKIQE 181
Cdd:PRK00409 504 IEEAKKLIGEDKEKL------NELIAS-LEELERELEQ---KAEEAEALLKEAEKL-KEELEE--KKEKLQEEEDKLLEE 570
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770412 182 LQEKLEKAVKAST-EATELLQNIR-----QAKERAERELEKLHNR-EDSSEGIKKKLVEAEERRHSLE 242
Cdd:PRK00409 571 AEKEAQQAIKEAKkEADEIIKELRqlqkgGYASVKAHELIEARKRlNKANEKKEKKKKKQKEKQEELK 638
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
9-218 |
3.07e-03 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 42.15 E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 9 MEQEMTRLHRRVSEVEAVLSQKEVELKA-----SETQRSLLEQ-------DLATYITEcssLKRSLEQARMEVSQ-EDDK 75
Cdd:pfam06160 184 LEEETDALEELMEDIPPLYEELKTELPDqleelKEGYREMEEEgyalehlNVDKEIQQ---LEEQLEENLALLENlELDE 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 76 ALQLLHDIREQSRKLQEIKEQEYQA-------------QVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFK- 141
Cdd:pfam06160 261 AEEALEEIEERIDQLYDLLEKEVDAkkyveknlpeiedYLEHAEEQNKELKEELERVQQSYTLNENELERVRGLEKQLEe 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 142 -RKANECQHKLMKAKDQGKPEVGE-----YSKLEKINAEQQlkiqELQEKLEKAVKASTEATELLQNIRQAKERAERELE 215
Cdd:pfam06160 341 lEKRYDEIVERLEEKEVAYSELQEeleeiLEQLEEIEEEQE----EFKESLQSLRKDELEAREKLDEFKLELREIKRLVE 416
|
...
gi 1039770412 216 KLH 218
Cdd:pfam06160 417 KSN 419
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
559-860 |
3.25e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 42.25 E-value: 3.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 559 EASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEqvlDLEALNDEL---LEKERQWEAWRSVLGD 635
Cdd:PRK04863 280 ERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQ---DYQAASDHLnlvQTALRQQEKIERYQAD 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 636 eksqfecrVRELQRMLDTEKQSRARADQRITESRQVVELA---VKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHA 712
Cdd:PRK04863 357 --------LEELEERLEEQNEVVEEADEQQEENEARAEAAeeeVDELKSQLADYQQALDVQQTRAIQYQQAVQALERAKQ 428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 713 ML---EMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQ------------EALDRADLLKTERSDL 777
Cdd:PRK04863 429 LCglpDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQlvrkiagevsrsEAWDVARELLRRLREQ 508
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 778 EYQLENIQVLYSHEKvKMEGTISQQTKLIDFLQAKMDQPAKKKKVPLQYNELKLALEKEKARCAELEEALQKTRIELRSA 857
Cdd:PRK04863 509 RHLAEQLQQLRMRLS-ELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQ 587
|
...
gi 1039770412 858 REE 860
Cdd:PRK04863 588 LEQ 590
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
661-797 |
3.44e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.07 E-value: 3.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 661 ADQRITESRQVVELAVKEHKAEILALQQALKEqklKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQA 740
Cdd:PRK12704 62 AKEEIHKLRNEFEKELRERRNELQKLEKRLLQ---KEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIE 138
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1039770412 741 KLQQQMDlqknHIFRLTQglQEAldRADLLKTERSDLEYQlenIQVLY--SHEKVKMEG 797
Cdd:PRK12704 139 EQLQELE----RISGLTA--EEA--KEILLEKVEEEARHE---AAVLIkeIEEEAKEEA 186
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
27-191 |
3.67e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.68 E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 27 LSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQeyQAQVEEMR 106
Cdd:COG1579 12 LQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQ--LGNVRNNK 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 107 lMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKANECQHKLMKAKDQGKPEVGEyskLEKINAEQQLKIQELQEKL 186
Cdd:COG1579 90 -EYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAE---LDEELAELEAELEELEAER 165
|
....*
gi 1039770412 187 EKAVK 191
Cdd:COG1579 166 EELAA 170
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
59-217 |
3.81e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 41.69 E-value: 3.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 59 KRSLEQARMEVSQEDDKAL----QLLHDIREQ-----SRKLQEIKEQEYQAQVEEMRLmmNQLEEDLVSARRRSDLYESE 129
Cdd:PRK12704 41 KRILEEAKKEAEAIKKEALleakEEIHKLRNEfekelRERRNELQKLEKRLLQKEENL--DRKLELLEKREEELEKKEKE 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 130 LRESRlaaEEFKRKANECQHKLMKAKDqgkpevgeysKLEKI---NAEQqlKIQELQEKLEKavKASTEATELLQNI-RQ 205
Cdd:PRK12704 119 LEQKQ---QELEKKEEELEELIEEQLQ----------ELERIsglTAEE--AKEILLEKVEE--EARHEAAVLIKEIeEE 181
|
170
....*....|..
gi 1039770412 206 AKERAERELEKL 217
Cdd:PRK12704 182 AKEEADKKAKEI 193
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
164-762 |
3.98e-03 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 42.05 E-value: 3.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 164 EYSKLEKINAEQQLKIQELQEKLEKAVKASTE--------ATELLQNIRQAKERAERELEKLHNREDSSegikkkLVEAE 235
Cdd:pfam07111 87 ETSLQQKMRLEAQAMELDALAVAEKAGQAEAEglraalagAEMVRKNLEEGSQRELEEIQRLHQEQLSS------LTQAH 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 236 ERrhSLENKVKRLETMERRENRLKddiQTKSEQIQQMAdkileleekhrEAQVSAQHLEVHLKQKEQHYEEKIKVLDNqI 315
Cdd:pfam07111 161 EE--ALSSLTSKAEGLEKSLNSLE---TKRAGEAKQLA-----------EAQKEAELLRKQLSKTQEELEAQVTLVES-L 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 316 KKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLaansslftqrnmkaQEEMISEL 395
Cdd:pfam07111 224 RKYVGEQVPPEVHSQTWELERQELLDTMQHLQEDRADLQATVELLQVRVQSLTHMLAL--------------QEEELTRK 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 396 RQQKFYLETQAGKleaqnrkleeqleKISHQDHSDKSRLLELETRLREVSLEHEEQKLELKRQLTE-------------- 461
Cdd:pfam07111 290 IQPSDSLEPEFPK-------------KCRSLLNRWREKVFALMVQLKAQDLEHRDSVKQLRGQVAElqeqvtsqsqeqai 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 462 LQLSLQERESQLTALQAARAALESQLRQAKTELEETTaeaeeeiQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTE 541
Cdd:pfam07111 357 LQRALQDKAAEVEVERMSAKGLQMELSRAQEARRRQQ-------QQTASAEEQLKFVVNAMSSTQIWLETTMTRVEQAVA 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 542 DNAELNNQNFYLSKQLDEASG---ANDEIVQLRSEVDHLRREITEREMQLTSQkqtMEALKTTCTMLEEQV-LDLEALND 617
Cdd:pfam07111 430 RIPSLSNRLSYAVRKVHTIKGlmaRKVALAQLRQESCPPPPPAPPVDADLSLE---LEQLREERNRLDAELqLSAHLIQQ 506
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 618 ELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKA 697
Cdd:pfam07111 507 EVGRAREQGEAERQQLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESTEEAASLRQELTQQQEIYGQALQEKVAEV 586
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039770412 698 ES-----LSD---KLNDLEKKHAMLEMNARSLQQKLETERELKQ---RLLEEQAKLQQQmdlqknhifRLTQGLQE 762
Cdd:pfam07111 587 ETrlreqLSDtkrRLNEARREQAKAVVSLRQIQHRATQEKERNQelrRLQDEARKEEGQ---------RLARRVQE 653
|
|
| C1_PKD_rpt2 |
cd20796 |
second protein kinase C conserved region 1 (C1 domain) found in the family of protein kinase D ... |
930-979 |
3.98e-03 |
|
second protein kinase C conserved region 1 (C1 domain) found in the family of protein kinase D (PKD); PKDs are important regulators of many intracellular signaling pathways such as ERK and JNK, and cellular processes including the organization of the trans-Golgi network, membrane trafficking, cell proliferation, migration, and apoptosis. They are activated in a PKC-dependent manner by many agents including diacylglycerol (DAG), PDGF, neuropeptides, oxidative stress, and tumor-promoting phorbol esters, among others. Mammals harbor three types of PKDs: PKD1 (or PKCmu), PKD2, and PKD3 (or PKCnu). PKDs contain N-terminal tandem cysteine-rich zinc binding C1 (PKC conserved region 1), central PH (Pleckstrin Homology), and C-terminal catalytic kinase domains. This model corresponds to the second C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410346 Cd Length: 54 Bit Score: 36.88 E-value: 3.98e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1039770412 930 PHRFNVGLNMRATKCAVCLDTVH-FGRQASKCLECQVMCHPKCSTCLPATC 979
Cdd:cd20796 1 PHTFVVHTYTKPTVCQHCKKLLKgLFRQGLQCKDCKFNCHKKCAEKVPKDC 51
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
11-244 |
4.15e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 41.34 E-value: 4.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 11 QEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQE-DDKALQLLHDIREQSRK 89
Cdd:pfam15905 87 QERGEQDKRLQALEEELEKVEAKLNAAVREKTSLSASVASLEKQLLELTRVNELLKAKFSEDgTQKKMSSLSMELMKLRN 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 90 LQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFK---RKANECQHKLMKAKDQGKPEVGEYS 166
Cdd:pfam15905 167 KLEAKMKEVMAKQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKsetEKLLEYITELSCVSEQVEKYKLDIA 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 167 KLEKINAEQQLKIQELQEKL-EKAVKAST---EATELLQNIRQAKERAEREL-EKLHNREDSSEGIKKKLVEAEERRHSL 241
Cdd:pfam15905 247 QLEELLKEKNDEIESLKQSLeEKEQELSKqikDLNEKCKLLESEKEELLREYeEKEQTLNAELEELKEKLTLEEQEHQKL 326
|
...
gi 1039770412 242 ENK 244
Cdd:pfam15905 327 QQK 329
|
|
| C1_TNS2 |
cd20887 |
protein kinase C conserved region 1 (C1 domain) found in tensin-2 and similar proteins; ... |
930-982 |
4.28e-03 |
|
protein kinase C conserved region 1 (C1 domain) found in tensin-2 and similar proteins; Tensin-2 (TNS2), also called C1 domain-containing phosphatase and tensin (C1-TEN), or tensin-like C1 domain-containing phosphatase (TENC1), is an essential component for the maintenance of glomerular basement membrane (GBM) structures. It regulates cell motility and proliferation. It may have phosphatase activity. TNS2 reduces AKT1 phosphorylation, lowers AKT1 kinase activity, and interferes with AKT1 signaling. It contains an N-terminal region with a zinc finger (C1 domain), a protein tyrosine phosphatase (PTP)-like domain and a protein kinase 2 (C2) domain, and a C-terminal region with SH2 and pTyr binding (PTB) domains. This model corresponds to the C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410437 Cd Length: 53 Bit Score: 37.07 E-value: 4.28e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1039770412 930 PHRFNVGLNMRATKCAVCLDTVhfGRQASKCLECQVMCHPKCSTCLPATCGLP 982
Cdd:cd20887 2 PHSFKEKTFKKKRACAVCREPV--GGQGLVCRVCKVASHKKCEAKVTSACQPP 52
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
258-454 |
4.78e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 41.54 E-value: 4.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 258 LKDDIQTKS-------EQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKESLENMMQ 330
Cdd:PHA02562 179 LNQQIQTLDmkidhiqQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALN 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 331 R----------------HEEEAHEKGKI-------LSEQKAMINAMDSKIRSLEQRIVELSEA-NKLAANSSLFTQRNMK 386
Cdd:PHA02562 259 KlntaaakikskieqfqKVIKMYEKGGVcptctqqISEGPDRITKIKDKLKELQHSLEKLDTAiDELEEIMDEFNEQSKK 338
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770412 387 AQeEMISELRQQKfyleTQAGKLEAQNRKLEEQLEKISHQDHSDKSRLLELETRLREVSLEHEEQKLE 454
Cdd:PHA02562 339 LL-ELKNKISTNK----QSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKE 401
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
67-405 |
5.04e-03 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 41.38 E-value: 5.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 67 MEVSQEDDKALQLLHDIREQSRK----LQEIKEQEyqaqvEEMRLMMNQLEEDLVSARR----RSDLYES--ELRESRLA 136
Cdd:pfam06160 82 KKAKKALDEIEELLDDIEEDIKQileeLDELLESE-----EKNREEVEELKDKYRELRKtllaNRFSYGPaiDELEKQLA 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 137 AEEFKRKANEcqhKLMkakdqgkpEVGEYSKLEKINAEQQLKIQELQEKLEKA----VKASTE----ATELLQNIRQAKE 208
Cdd:pfam06160 157 EIEEEFSQFE---ELT--------ESGDYLEAREVLEKLEEETDALEELMEDIpplyEELKTElpdqLEELKEGYREMEE 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 209 --------RAERELEKLHNR-EDSSEGIKK-KLVEAEERRHSLENKVKRL-ETMErRENRLKDDIQTKSEQIQQMadkIL 277
Cdd:pfam06160 226 egyalehlNVDKEIQQLEEQlEENLALLENlELDEAEEALEEIEERIDQLyDLLE-KEVDAKKYVEKNLPEIEDY---LE 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 278 ELEEKHREAQVSAQHLEV--HLKQKEqhyEEKIKVLDNQIkkdladkESLENMMQRHEEEAHEKGKILSEQKAMINAMDS 355
Cdd:pfam06160 302 HAEEQNKELKEELERVQQsyTLNENE---LERVRGLEKQL-------EELEKRYDEIVERLEEKEVAYSELQEELEEILE 371
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1039770412 356 KIRSLEQRIVELSEanKLAansSLFTQrNMKAQE---EMISELRQQKFYLETQ 405
Cdd:pfam06160 372 QLEEIEEEQEEFKE--SLQ---SLRKD-ELEAREkldEFKLELREIKRLVEKS 418
|
|
| pepcterm_ChnLen |
TIGR03007 |
polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Members of this ... |
570-749 |
5.07e-03 |
|
polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Members of this protein family belong to the family of polysaccharide chain length determinant proteins (pfam02706). All are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria, and are found near the epsH homolog that is the putative exosortase gene. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
Pssm-ID: 274386 [Multi-domain] Cd Length: 498 Bit Score: 41.19 E-value: 5.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 570 LRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLE-----EQVLDLEALNDELLEKERQWEAWRSVLGDEKSQFEcRV 644
Cdd:TIGR03007 202 YYSEISEAQEELEAARLELNEAIAQRDALKRQLGGEEpvllaGSSVANSELDGRIEALEKQLDALRLRYTDKHPDVI-AT 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 645 RELQRMLDTEKQSRARADQRITESR-------QVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEmn 717
Cdd:TIGR03007 281 KREIAQLEEQKEEEGSAKNGGPERGeianpvyQQLQIELAEAEAEIASLEARVAELTARIERLESLLRTIPEVEAELT-- 358
|
170 180 190
....*....|....*....|....*....|....
gi 1039770412 718 arSLQQKLETERELKQRLLE--EQAKLQQQMDLQ 749
Cdd:TIGR03007 359 --QLNRDYEVNKSNYEQLLTrrESAEVSKQMEVQ 390
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
677-866 |
5.09e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 41.30 E-value: 5.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 677 KEHKAEILAlQQALKEQKLKAESLsdklndleKKHAMLEMNARSLQQKLETERELKQRLLEEQaKLQQQMdLQKnhifrl 756
Cdd:PRK12704 32 KIKEAEEEA-KRILEEAKKEAEAI--------KKEALLEAKEEIHKLRNEFEKELRERRNELQ-KLEKRL-LQK------ 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 757 tqglQEALDR-ADLLKTERSDLEYQLENIqvlySHEKVKMEGTISQQTKLIDFLQAKMDQPAkkkkvplqynelklALEK 835
Cdd:PRK12704 95 ----EENLDRkLELLEKREEELEKKEKEL----EQKQQELEKKEEELEELIEEQLQELERIS--------------GLTA 152
|
170 180 190
....*....|....*....|....*....|....*...
gi 1039770412 836 EKARCAELEEALQKTRIE----LRSAREEA---AHRKA 866
Cdd:PRK12704 153 EEAKEILLEKVEEEARHEaavlIKEIEEEAkeeADKKA 190
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
173-398 |
5.83e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.97 E-value: 5.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 173 AEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLHNREDSsegIKKKLVEAEERRHSLENKV-KRLETM 251
Cdd:COG3883 19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDK---LQAEIAEAEAEIEERREELgERARAL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 252 ERRENRLKD-DIQTKSEQIQQMADKILELEekhreaQVSAQHLEVHLKQKEQhyEEKIKVLDNQIKKDLADKESLENMMQ 330
Cdd:COG3883 96 YRSGGSVSYlDVLLGSESFSDFLDRLSALS------KIADADADLLEELKAD--KAELEAKKAELEAKLAELEALKAELE 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039770412 331 RHEEEAHEKgkiLSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQ 398
Cdd:COG3883 168 AAKAELEAQ---QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
535-875 |
5.99e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 41.43 E-value: 5.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 535 QLNQLTEDNAELNNQnfyLSKQLDEASGANDEIVQLRSEVDHLRREITEREmqLTSQKQTMEalKTTCTMLEEQVLDLEA 614
Cdd:PLN02939 85 ELPQKSTSSDDDHNR---ASMQRDEAIAAIDNEQQTNSKDGEQLSDFQLED--LVGMIQNAE--KNILLLNQARLQALED 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 615 LNDELLEKERqweawrsvLGDEKSQFECRVRELQRMLDTEKQSRARAD--------------QRITESRQVVELAVKEH- 679
Cdd:PLN02939 158 LEKILTEKEA--------LQGKINILEMRLSETDARIKLAAQEKIHVEileeqleklrnellIRGATEGLCVHSLSKELd 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 680 --KAEILALQ---QALKEQKLKAESLSDKLNDLEKKHAMLEmnarslqqklETERELKQRLLEEQAKLQQQMDLQKNHIF 754
Cdd:PLN02939 230 vlKEENMLLKddiQFLKAELIEVAETEERVFKLEKERSLLD----------ASLRELESKFIVAQEDVSKLSPLQYDCWW 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 755 RLTQGLQEALDRAdllkTERSDleyqlENIQVLYSHEKVKmegtisqqtKLIDFLQAKMDQPAKKK----KVPLQYNELK 830
Cdd:PLN02939 300 EKVENLQDLLDRA----TNQVE-----KAALVLDQNQDLR---------DKVDKLEASLKEANVSKfssyKVELLQQKLK 361
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1039770412 831 LALEKEKARCAEL-------EEALQKTRIELRSAREEAAhRKATDHPHPSTP 875
Cdd:PLN02939 362 LLEERLQASDHEIhsyiqlyQESIKEFQDTLSKLKEESK-KRSLEHPADDMP 412
|
|
| C1_Munc13 |
cd20807 |
protein kinase C conserved region 1 (C1 domain) found in the Munc13 family; The Munc13 gene ... |
931-979 |
6.14e-03 |
|
protein kinase C conserved region 1 (C1 domain) found in the Munc13 family; The Munc13 gene family encodes a family of neuron-specific, synaptic molecules that bind to syntaxin, an essential mediator of neurotransmitter release. Munc13-1 is a component of presynaptic active zones in which it acts as an essential synaptic vesicle priming protein. Munc13-2 is essential for normal release probability at hippocampal mossy fiber synapses. Munc13-3 is almost exclusively expressed in the cerebellum. It acts as a tumor suppressor and plays a critical role in the formation of release sites with calcium channel nanodomains. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410357 Cd Length: 53 Bit Score: 36.30 E-value: 6.14e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1039770412 931 HRFNVGLNMRATKCAVCLDTV-HFGRQASKCLECQVMCHPKCSTCLPATC 979
Cdd:cd20807 1 HNFEVWTATTPTYCYECEGLLwGIARQGVRCTECGVKCHEKCKDLLNADC 50
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
198-298 |
6.38e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 41.22 E-value: 6.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 198 ELLQNIRQAKERAERELEKLhnREDSSEGIKKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSEQIQQMADKIL 277
Cdd:COG0542 411 EELDELERRLEQLEIEKEAL--KKEQDEASFERLAELRDELAELEEELEALKARWEAEKELIEEIQELKEELEQRYGKIP 488
|
90 100
....*....|....*....|.
gi 1039770412 278 ELEEKHREAQVSAQHLEVHLK 298
Cdd:COG0542 489 ELEKELAELEEELAELAPLLR 509
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
305-487 |
7.41e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.91 E-value: 7.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 305 EEKIKVLDNQIKKDLADKESLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRivelseanklaanssLFTQRN 384
Cdd:COG1579 23 EHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQ---------------LGNVRN 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 385 MKAQEEMISELRqqkfYLETQAGKLEAQNRKLEEQLEkishqdhsdksrllELETRLREVSLEHEEQKLELKRQLTELQL 464
Cdd:COG1579 88 NKEYEALQKEIE----SLKRRISDLEDEILELMERIE--------------ELEEELAELEAELAELEAELEEKKAELDE 149
|
170 180
....*....|....*....|...
gi 1039770412 465 SLQERESQLTALQAARAALESQL 487
Cdd:COG1579 150 ELAELEAELEELEAEREELAAKI 172
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
566-862 |
7.82e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 40.99 E-value: 7.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 566 EIVQLRSEVDHLRREITEREMqlTSQKQTMEALKTTCTMLEEQVlDLEALND-ELLEKERQWEAWRSVLGDEKSQFECRV 644
Cdd:PLN03229 430 PVRELEGEVEKLKEQILKAKE--SSSKPSELALNEMIEKLKKEI-DLEYTEAvIAMGLQERLENLREEFSKANSQDQLMH 506
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 645 RELQRMLDTEKQSrarADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLND--------LEKKHAMLEM 716
Cdd:PLN03229 507 PVLMEKIEKLKDE---FNKRLSRAPNYLSLKYKLDMLNEFSRAKALSEKKSKAEKLKAEINKkfkevmdrPEIKEKMEAL 583
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 717 NARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRlTQGLQEALDRADLLKTERSDLEYQL-ENIQVLYSHEKVKM 795
Cdd:PLN03229 584 KAEVASSGASSGDELDDDLKEKVEKMKKEIELELAGVLK-SMGLEVIGVTKKNKDTAEQTPPPNLqEKIESLNEEINKKI 662
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039770412 796 EGTI--SQQTKLIDFLQAKMDQPAKKKKVPLQYNELKLALE-KEKARCA----ELEEALQKTRIELRSAREEAA 862
Cdd:PLN03229 663 ERVIrsSDLKSKIELLKLEVAKASKTPDVTEKEKIEALEQQiKQKIAEAlnssELKEKFEELEAELAAARETAA 736
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
457-748 |
8.96e-03 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 40.81 E-value: 8.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 457 RQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITD----- 531
Cdd:PRK10929 2 RLIITFLMAWLLSWGAYAATAPDEKQITQELEQAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQYQQVIDNfpkls 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 532 --LEEQLNQLTED---------NAELNNQNFYLSKQLDEASGandeivQLRSEVDHLrREITEREMQLTsQKQTmEALKt 600
Cdd:PRK10929 82 aeLRQQLNNERDEprsvppnmsTDALEQEILQVSSQLLEKSR------QAQQEQDRA-REISDSLSQLP-QQQT-EARR- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 601 tctMLEEQVLDLEALNDELLEKErqwEAWRSVLGDEKSQFECRVRELQrmldtekQSRARADQRITESRQVVELAVKEHk 680
Cdd:PRK10929 152 ---QLNEIERRLQTLGTPNTPLA---QAQLTALQAESAALKALVDELE-------LAQLSANNRQELARLRSELAKKRS- 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 681 AEILALQQALKEQklkaeslsdkLNDLEKKHA--------MLEMNA----RSLQQKLETERELKQrLLEEQAklqQQMDL 748
Cdd:PRK10929 218 QQLDAYLQALRNQ----------LNSQRQREAeralesteLLAEQSgdlpKSIVAQFKINRELSQ-ALNQQA---QRMDL 283
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
11-290 |
9.83e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 40.71 E-value: 9.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 11 QEMTRLHRRVSE------VEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQ-----------ED 73
Cdd:COG3096 809 QKLQRLHQAFSQfvgghlAVAFAPDPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLlnkllpqanllAD 888
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 74 DKALQLLHDIREQSRKLQEIKE--QEYQAQVEEMrlmmnqleEDLVSARRRSDLYESELRESRLAAEEFKRKAnecQHKL 151
Cdd:COG3096 889 ETLADRLEELREELDAAQEAQAfiQQHGKALAQL--------EPLVAVLQSDPEQFEQLQADYLQAKEQQRRL---KQQI 957
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 152 MKAKD--QGKPEVGeYSKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNI-----------------RQAKER--- 209
Cdd:COG3096 958 FALSEvvQRRPHFS-YEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQAqaqysqynqvlaslkssRDAKQQtlq 1036
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 210 -AERELEKLHNREDSsegikkklvEAEERRHSLENKVK-RLETMERRENRLKDDIQTKSEQIQQMADKILELEEKH---R 284
Cdd:COG3096 1037 eLEQELEELGVQADA---------EAEERARIRRDELHeELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYkqeR 1107
|
....*.
gi 1039770412 285 EAQVSA 290
Cdd:COG3096 1108 EQVVQA 1113
|
|
| Filament |
pfam00038 |
Intermediate filament protein; |
430-747 |
9.99e-03 |
|
Intermediate filament protein;
Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 39.90 E-value: 9.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 430 DKSRLLELETRLREVSL-EHEEQKLELKRQLTEL-QLSLQERESQLTALQAARAALESQLRQAkteleettaeaeeeiqa 507
Cdd:pfam00038 18 DKVRFLEQQNKLLETKIsELRQKKGAEPSRLYSLyEKEIEDLRRQLDTLTVERARLQLELDNL----------------- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 508 ltahRDEIQRkfdaLRNSctvitdLEEQLNQLTEDNAELNNqnfyLSKQLDEASGANDE----IVQLRSEVDHLRR---- 579
Cdd:pfam00038 81 ----RLAAED----FRQK------YEDELNLRTSAENDLVG----LRKDLDEATLARVDleakIESLKEELAFLKKnhee 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 580 EITEREMQLTSQKQTMEALKTTCTMLEEQVLDLEALNDELLEKERQweawrsvlgDEKSQFECRVRELQRMLDTEKQSRA 659
Cdd:pfam00038 143 EVRELQAQVSDTQVNVEMDAARKLDLTSALAEIRAQYEEIAAKNRE---------EAEEWYQSKLEELQQAAARNGDALR 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039770412 660 RADQRITESRQVVElavkehkaeilALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETE-RELKQRLLEE 738
Cdd:pfam00038 214 SAKEEITELRRTIQ-----------SLEIELQSLKKQKASLERQLAETEERYELQLADYQELISELEAElQETRQEMARQ 282
|
....*....
gi 1039770412 739 QAKLQQQMD 747
Cdd:pfam00038 283 LREYQELLN 291
|
|
| |
