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Conserved domains on  [gi|1039749236|ref|XP_017172192|]
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protein FAM186B isoform X2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK13729 super family cl42933
conjugal transfer pilus assembly protein TraB; Provisional
 104-220 6.25e-05

conjugal transfer pilus assembly protein TraB; Provisional


The actual alignment was detected with superfamily member PRK13729:

Pssm-ID: 184281 [Multi-domain]  Cd Length: 475  Bit Score: 46.35  E-value: 6.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749236 104 MSAVVENL------NKALTLQHKENKSLETKYKYLQVEKNKeLSTQRLHFQKSIQVLESKRDALLKQVKILGdkyhhllm 177
Cdd:PRK13729   54 MTGVVDTTfddkvrQHATTEMQVTAAQMQKQYEEIRRELDV-LNKQRGDDQRRIEKLGQDNAALAEQVKALG-------- 124

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1039749236 178 lkhtlefqlniAQPASGPEEPTKHFIHYLEPPEKEPLPGQGTA 220
Cdd:PRK13729  125 -----------ANPVTATGEPVPQMPASPPGPEGEPQPGNTPV 156
DDRGK super family cl25550
DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and ...
 344-407 3.62e-03

DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.


The actual alignment was detected with superfamily member pfam09756:

Pssm-ID: 370664 [Multi-domain]  Cd Length: 188  Bit Score: 39.25  E-value: 3.62e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039749236 344 ETRRQQWLQEEEMWLQRQKKWALLEQEHQEKVRQWEAEAAARQQWQRLTQPEEEkpspRKEQKA 407
Cdd:pfam09756  15 EAKRQQREAEEEEREEREKLEEKREEEYKEREEREEEAEKEKEEEERKQEEEQE----RKEQEE 74
 
Name Accession Description Interval E-value
PRK13729 PRK13729
conjugal transfer pilus assembly protein TraB; Provisional
 104-220 6.25e-05

conjugal transfer pilus assembly protein TraB; Provisional


Pssm-ID: 184281 [Multi-domain]  Cd Length: 475  Bit Score: 46.35  E-value: 6.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749236 104 MSAVVENL------NKALTLQHKENKSLETKYKYLQVEKNKeLSTQRLHFQKSIQVLESKRDALLKQVKILGdkyhhllm 177
Cdd:PRK13729   54 MTGVVDTTfddkvrQHATTEMQVTAAQMQKQYEEIRRELDV-LNKQRGDDQRRIEKLGQDNAALAEQVKALG-------- 124

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1039749236 178 lkhtlefqlniAQPASGPEEPTKHFIHYLEPPEKEPLPGQGTA 220
Cdd:PRK13729  125 -----------ANPVTATGEPVPQMPASPPGPEGEPQPGNTPV 156
DDRGK pfam09756
DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and ...
 344-407 3.62e-03

DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.


Pssm-ID: 370664 [Multi-domain]  Cd Length: 188  Bit Score: 39.25  E-value: 3.62e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039749236 344 ETRRQQWLQEEEMWLQRQKKWALLEQEHQEKVRQWEAEAAARQQWQRLTQPEEEkpspRKEQKA 407
Cdd:pfam09756  15 EAKRQQREAEEEEREEREKLEEKREEEYKEREEREEEAEKEKEEEERKQEEEQE----RKEQEE 74
 
Name Accession Description Interval E-value
PRK13729 PRK13729
conjugal transfer pilus assembly protein TraB; Provisional
 104-220 6.25e-05

conjugal transfer pilus assembly protein TraB; Provisional


Pssm-ID: 184281 [Multi-domain]  Cd Length: 475  Bit Score: 46.35  E-value: 6.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749236 104 MSAVVENL------NKALTLQHKENKSLETKYKYLQVEKNKeLSTQRLHFQKSIQVLESKRDALLKQVKILGdkyhhllm 177
Cdd:PRK13729   54 MTGVVDTTfddkvrQHATTEMQVTAAQMQKQYEEIRRELDV-LNKQRGDDQRRIEKLGQDNAALAEQVKALG-------- 124

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1039749236 178 lkhtlefqlniAQPASGPEEPTKHFIHYLEPPEKEPLPGQGTA 220
Cdd:PRK13729  125 -----------ANPVTATGEPVPQMPASPPGPEGEPQPGNTPV 156
DDRGK pfam09756
DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and ...
 344-407 3.62e-03

DDRGK domain; This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.


Pssm-ID: 370664 [Multi-domain]  Cd Length: 188  Bit Score: 39.25  E-value: 3.62e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039749236 344 ETRRQQWLQEEEMWLQRQKKWALLEQEHQEKVRQWEAEAAARQQWQRLTQPEEEkpspRKEQKA 407
Cdd:pfam09756  15 EAKRQQREAEEEEREEREKLEEKREEEYKEREEREEEAEKEKEEEERKQEEEQE----RKEQEE 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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