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Conserved domains on  [gi|1039790844|ref|XP_017168477|]
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trimeric intracellular cation channel type A isoform X2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TRIC super family cl20290
TRIC channel; TRIC (trimeric intracellular cation) channels are differentially expressed in ...
 43-156 3.22e-49

TRIC channel; TRIC (trimeric intracellular cation) channels are differentially expressed in intracellular stores in animal cell types. TRIC subtypes contain three proposed transmembrane segments, and form homo-trimers with a bullet-like structure. Electrophysiological measurements with purified TRIC preparations identify a monovalent cation-selective channel.


The actual alignment was detected with superfamily member pfam05197:

Pssm-ID: 461583  Cd Length: 185  Bit Score: 158.14  E-value: 3.22e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039790844  43 AVELSRRHPVASWLCAMLHCFGSYILADLLLGEPIIDYFSNSSSILLASGVWYLIFFCPLDLFYKCVCFLPVKLIFVAMK 122
Cdd:pfam05197   1 AVAFSRKHPLACWLSSMLMCFAGSILSNFLLGEPPLAPLKNTQDVLLATAIWYLVFYCPFDLVYKLASFLPVKLVLAAMK 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1039790844 123 EVVRVRKIAVGIHHAHHHYHHGWFIMIATGWVKA 156
Cdd:pfam05197  81 EVTRTKKILDGVSHAAKVYPNAYLVMIIVGTAKG 114
 
Name Accession Description Interval E-value
TRIC pfam05197
TRIC channel; TRIC (trimeric intracellular cation) channels are differentially expressed in ...
 43-156 3.22e-49

TRIC channel; TRIC (trimeric intracellular cation) channels are differentially expressed in intracellular stores in animal cell types. TRIC subtypes contain three proposed transmembrane segments, and form homo-trimers with a bullet-like structure. Electrophysiological measurements with purified TRIC preparations identify a monovalent cation-selective channel.


Pssm-ID: 461583  Cd Length: 185  Bit Score: 158.14  E-value: 3.22e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039790844  43 AVELSRRHPVASWLCAMLHCFGSYILADLLLGEPIIDYFSNSSSILLASGVWYLIFFCPLDLFYKCVCFLPVKLIFVAMK 122
Cdd:pfam05197   1 AVAFSRKHPLACWLSSMLMCFAGSILSNFLLGEPPLAPLKNTQDVLLATAIWYLVFYCPFDLVYKLASFLPVKLVLAAMK 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1039790844 123 EVVRVRKIAVGIHHAHHHYHHGWFIMIATGWVKA 156
Cdd:pfam05197  81 EVTRTKKILDGVSHAAKVYPNAYLVMIIVGTAKG 114
 
Name Accession Description Interval E-value
TRIC pfam05197
TRIC channel; TRIC (trimeric intracellular cation) channels are differentially expressed in ...
 43-156 3.22e-49

TRIC channel; TRIC (trimeric intracellular cation) channels are differentially expressed in intracellular stores in animal cell types. TRIC subtypes contain three proposed transmembrane segments, and form homo-trimers with a bullet-like structure. Electrophysiological measurements with purified TRIC preparations identify a monovalent cation-selective channel.


Pssm-ID: 461583  Cd Length: 185  Bit Score: 158.14  E-value: 3.22e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039790844  43 AVELSRRHPVASWLCAMLHCFGSYILADLLLGEPIIDYFSNSSSILLASGVWYLIFFCPLDLFYKCVCFLPVKLIFVAMK 122
Cdd:pfam05197   1 AVAFSRKHPLACWLSSMLMCFAGSILSNFLLGEPPLAPLKNTQDVLLATAIWYLVFYCPFDLVYKLASFLPVKLVLAAMK 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1039790844 123 EVVRVRKIAVGIHHAHHHYHHGWFIMIATGWVKA 156
Cdd:pfam05197  81 EVTRTKKILDGVSHAAKVYPNAYLVMIIVGTAKG 114
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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