|
Name |
Accession |
Description |
Interval |
E-value |
| CEP209_CC5 |
pfam16574 |
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry ... |
1289-1416 |
9.33e-44 |
|
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry a number of coiled-coil regions, and this is the fifth along the length of the protein. It is thought that the proteins are involved in cilia biosynthesis.
Pssm-ID: 465184 [Multi-domain] Cd Length: 128 Bit Score: 156.01 E-value: 9.33e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1289 TMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKVINWHMKIEELRLQELKLNRELVKD 1368
Cdd:pfam16574 1 TMIQLQEDKAKLQEELKHAEEERRRAEDRAQELELKLKGLEELISTLKDGKGAQKVTEWHKKMEEIRLQELKLQRELSKQ 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 767975376 1369 KEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLER 1416
Cdd:pfam16574 81 KEEIKYLENLIREQERTISSLEEEIVQQTKLHEERQLAWDQREVELER 128
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1082-1889 |
9.25e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 77.79 E-value: 9.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1082 HLRTSLKQMEERNFELETKFAELTKinldaqkvEQMLRDELADSVSKAVSDADRqriLELEKNEMELKVEV------SKL 1155
Cdd:TIGR02168 226 ELALLVLRLEELREELEELQEELKE--------AEEELEELTAELQELEEKLEE---LRLEVSELEEEIEElqkelyALA 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1156 REISDIaRRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKlhqhnvSLQLSEATALGKLESITSKLQKMEAYN 1235
Cdd:TIGR02168 295 NEISRL-EQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA------ELEEKLEELKEELESLEAELEELEAEL 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1236 LRLEQKLDEKEQALYYARlegrNRAKHLRQTIQSLRRQFsgalplaQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNME 1315
Cdd:TIGR02168 368 EELESRLEELEEQLETLR----SKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKKLEEAELK 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1316 NKTLEMELKLKGLEELISTLKDTkgAQKVINWHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQ 1395
Cdd:TIGR02168 437 ELQAELEELEEELEELQEELERL--EEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN 514
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1396 QNKFHEERQMAWDQREVDLERQLDIF----DRQQNEILNAAQKFEEATGSIPDPSLPLPNQLE---IALRKIKENIRIIL 1468
Cdd:TIGR02168 515 QSGLSGILGVLSELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPldsIKGTEIQGNDREIL 594
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1469 ETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELR--LRLPATAEREKLIAELGRKEMEPKSHHTLKIAhQTIANMQ 1546
Cdd:TIGR02168 595 KNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDnaLELAKKLRPGYRIVTLDGDLVRPGGVITGGSA-KTNSSIL 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1547 ARLNQKEEVLKKYQRLLEKAREEQREIVkkheedlhilhhRLELQADSSLNKFKQTAWDLMKQSPTPVPTNKHFIRLAEM 1626
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIAELEKALA------------ELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAE 741
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1627 EQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEfeniklqlqenHEDEVKKVKAEVEDLKYLLDQSQKESQCLKS 1706
Cdd:TIGR02168 742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE-----------AEAEIEELEAQIEQLKEELKALREALDELRA 810
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1707 ELQAQKEANSRAptttmRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDrhtre 1786
Cdd:TIGR02168 811 ELTLLNEEAANL-----RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLN----- 880
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1787 lktQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG--K 1864
Cdd:TIGR02168 881 ---ERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEeaE 957
|
810 820
....*....|....*....|....*
gi 767975376 1865 PLTDNKQSLIEELQRKVKKLENQLE 1889
Cdd:TIGR02168 958 ALENKIEDDEEEARRRLKRLENKIK 982
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1462-2348 |
1.27e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 77.02 E-value: 1.27e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1462 ENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPaTAEREKLIAELGRKEMEPKSHHTLKIAHQT 1541
Cdd:TIGR02168 155 EERRAIFEEAAGISKYKERRKETERKLERTRENLDRLEDILNELERQLK-SLERQAEKAERYKELKAELRELELALLVLR 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1542 IANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEdlhilhHRLELQADSSLNKFKQTAWDLMKQsptpvptnkhfi 1621
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEE------LRLEVSELEEEIEELQKELYALAN------------ 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1622 RLAEMEQTVAEQDDSLSSLLVKLKKVS---QDLERQREITELKVKEFENIKLQLQENHE---DEVKKVKAEVEDLKYLLD 1695
Cdd:TIGR02168 296 EISRLEQQKQILRERLANLERQLEELEaqlEELESKLDELAEELAELEEKLEELKEELEsleAELEELEAELEELESRLE 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1696 QSQKESQCLKSEL-QAQKEANSraptttMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHL 1774
Cdd:TIGR02168 376 ELEEQLETLRSKVaQLELQIAS------LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL 449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1775 -NVQQIVDRHTRELKTQVEDLNENLLKLKEAlKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQ 1853
Cdd:TIGR02168 450 eELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL 528
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1854 IK-----------RLTSGLQgKPLTDNKQSLIEElqrkVKKLENQLEGKVE--EVDLKPMKEKNAKEELIRweegkkwqA 1920
Cdd:TIGR02168 529 ISvdegyeaaieaALGGRLQ-AVVVENLNAAKKA----IAFLKQNELGRVTflPLDSIKGTEIQGNDREIL--------K 595
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1921 KIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADkekltlqrklkttgmTVDQVLGIRalesekELEELKKRNLDLENDI 2000
Cdd:TIGR02168 596 NIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVD---------------DLDNALELA------KKLRPGYRIVTLDGDL 654
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2001 LY----------MRAHQALPRDSVVEDLHLQNRYLQEKLHALEKQFskdtyskpsqnqisgiesDDHCQREQELQKENLK 2070
Cdd:TIGR02168 655 VRpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKAL------------------AELRKELEELEEELEQ 716
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2071 LSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEVQRKLGHVRgsGRSGKTIPELEKTIGLMKKVVEKVQRE 2150
Cdd:TIGR02168 717 LRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE--ERLEEAEEELAEAEAEIEELEAQIEQL 794
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2151 NEQLKKasgiltsekmanIEQENEKLKAELEKLKAHLgHQLSMHYESKTKGTEKIIAENERLRKELKKETDAAEKLRIAK 2230
Cdd:TIGR02168 795 KEELKA------------LREALDELRAELTLLNEEA-ANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2231 NNLEILNEKMTVQLEETGKRLQFAESRGPQLEGADSKSWKSIvvtRMYETKLKELETDIAKKNQSITDLKQ-----LVKE 2305
Cdd:TIGR02168 862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEEL---RELESKRSELRRELEELREKLAQLELrleglEVRI 938
|
890 900 910 920
....*....|....*....|....*....|....*....|...
gi 767975376 2306 ATEREQKVNKYNEDLEQqikILKHVPEGAETEQGLKRELQVLR 2348
Cdd:TIGR02168 939 DNLQERLSEEYSLTLEE---AEALENKIEDDEEEARRRLKRLE 978
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
524-1275 |
2.03e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 66.62 E-value: 2.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 524 KHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQERgkRSATSGLTTEDLNLTENISQGDRISERKLD----LLSL 599
Cdd:TIGR02168 216 KELKAELRELELALLVLRLEELREELEELQEELKEAEEEL--EELTAELQELEEKLEELRLEVSELEEEIEElqkeLYAL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 600 KN-MSEAQSKNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDpdvkggetsliIPS 678
Cdd:TIGR02168 294 ANeISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAE-----------LEE 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 679 LERLVNAIESKNAEgifdaslhLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQSEGSNV 758
Cdd:TIGR02168 363 LEAELEELESRLEE--------LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 759 VFK---GIDLPDGIAPSSASIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKETWKt 835
Cdd:TIGR02168 435 LKElqaELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK- 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 836 esktiKEEKRKLEDQVQQDAIKV-KEYNNLLNALqmdsdemkkiLAENSRKITVLQVNEKSLIRQYTTLVELER------ 908
Cdd:TIGR02168 514 -----NQSGLSGILGVLSELISVdEGYEAAIEAA----------LGGRLQAVVVENLNAAKKAIAFLKQNELGRvtflpl 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 909 QLRKENEKQKNELLSMEAEVCEKIGCLQRFKEMAIFKIAaLQKVVDNSVSLSELELANKQYNELTAKYRDI--------- 979
Cdd:TIGR02168 579 DSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA-LSYLLGGVLVVDDLDNALELAKKLRPGYRIVtldgdlvrp 657
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 980 --------LQKDNMLVQRTSNLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQETKLGNEssmdkakksitnsd 1051
Cdd:TIGR02168 658 ggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE-------------- 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1052 ivsISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKiNLDAQKVEQMLRDELADSVSKAVS 1131
Cdd:TIGR02168 724 ---LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE-ELAEAEAEIEELEAQIEQLKEELK 799
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1132 dADRQRILELEKNEMELKVEVSKLRE-----ISDIARRQVEILNAQQQSRDK--EVESLRMQLLDYQAQSDEKSLIAKLH 1204
Cdd:TIGR02168 800 -ALREALDELRAELTLLNEEAANLRErleslERRIAATERRLEDLEEQIEELseDIESLAAEIEELEELIEELESELEAL 878
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767975376 1205 QHNV-SLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQAL--YYARLEGrnrakhLRQTIQSLRRQFS 1275
Cdd:TIGR02168 879 LNERaSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLaqLELRLEG------LEVRIDNLQERLS 946
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
93-868 |
4.06e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.85 E-value: 4.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 93 KLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKK 172
Cdd:TIGR02168 217 ELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 173 NEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEK 252
Cdd:TIGR02168 297 ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 253 MTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTD-LLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQML 331
Cdd:TIGR02168 377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDrRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEEL 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 332 HNLREKLKNA--QLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKntcIIEDLKNELQRNKGASTLSQQthMKI 409
Cdd:TIGR02168 457 ERLEEALEELreELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG---VKALLKNQSGLSGILGVLSEL--ISV 531
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 410 QSTLDILKEKTKEAERTAELAEADarEKDKELVEALKRLKDYESGVYGLEDA-----VVEIKNCKNQIKIRDREIEILTK 484
Cdd:TIGR02168 532 DEGYEAAIEAALGGRLQAVVVENL--NAAKKAIAFLKQNELGRVTFLPLDSIkgteiQGNDREILKNIEGFLGVAKDLVK 609
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 485 EINKLELKISDFL-------DENEALRERVGLEPKTMI---DLTEFRNSKHLKQQQYRAENQILL--KEIESLEEERLDL 552
Cdd:TIGR02168 610 FDPKLRKALSYLLggvlvvdDLDNALELAKKLRPGYRIvtlDGDLVRPGGVITGGSAKTNSSILErrREIEELEEKIEEL 689
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 553 KKKIR--QMAQERGKRSATSGLTTEDLNLTENISQGDRISERKLDLLSLKNMSE-AQSKNEFLSRELIEKERDLERSRTV 629
Cdd:TIGR02168 690 EEKIAelEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEqLEERIAQLSKELTELEAEIEELEER 769
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 630 IAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIESknaegifdaslhLKAQVDQLT 709
Cdd:TIGR02168 770 LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES------------LERRIAATE 837
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 710 GRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKE-TSLLRQSEGSNVvfkgidlpdgiapsSASIINSQNEYLIHLL 788
Cdd:TIGR02168 838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESElEALLNERASLEE--------------ALALLRSELEELSEEL 903
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 789 QELENK----EKKLKNLEDSLEDYNRKFAVIRhQQSLLYKEYLSEKetWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNL 864
Cdd:TIGR02168 904 RELESKrselRRELEELREKLAQLELRLEGLE-VRIDNLQERLSEE--YSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
|
....
gi 767975376 865 LNAL 868
Cdd:TIGR02168 981 IKEL 984
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1219-1944 |
7.91e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 64.69 E-value: 7.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1219 GKLESITSKLQKMEAYnLRLEQKLDEKEQALYYARLEGRNraKHLRQTIQSLRRQfsgalplaqQEKFSKTMIQLQNDKL 1298
Cdd:TIGR02168 200 RQLKSLERQAEKAERY-KELKAELRELELALLVLRLEELR--EELEELQEELKEA---------EEELEELTAELQELEE 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1299 KIMQEMKnsqqEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKV--INWHMKIEELRLQELKLNRELVKDKEEIKYLN 1376
Cdd:TIGR02168 268 KLEELRL----EVSELEEEIEELQKELYALANEISRLEQQKQILRErlANLERQLEELEAQLEELESKLDELAEELAELE 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1377 NIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPD------------ 1444
Cdd:TIGR02168 344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERledrrerlqqei 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1445 ---PSLPLPNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAEREkliae 1521
Cdd:TIGR02168 424 eelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ----- 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1522 lGRKEMEPKSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQRE-IVKKHEEDLhilhhRLELQADSSLNKFK 1600
Cdd:TIGR02168 499 -ENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQaVVVENLNAA-----KKAIAFLKQNELGR 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1601 QTAWDLMKQSPTPVPTNKHFIR---------LAEMEQTVAEQDDSLSSLLVKL--------------------------- 1644
Cdd:TIGR02168 573 VTFLPLDSIKGTEIQGNDREILkniegflgvAKDLVKFDPKLRKALSYLLGGVlvvddldnalelakklrpgyrivtldg 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1645 --------------KKVSQDLERQREITELKvkefENIKLQLQENHE--DEVKKVKAEVEDLKYLLDQSQKESQCLKSEL 1708
Cdd:TIGR02168 653 dlvrpggvitggsaKTNSSILERRREIEELE----EKIEELEEKIAEleKALAELRKELEELEEELEQLRKELEELSRQI 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1709 QAQKEansraptttmrnLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAhlnvqqivdrhtrelK 1788
Cdd:TIGR02168 729 SALRK------------DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA---------------E 781
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1789 TQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG-KPLT 1867
Cdd:TIGR02168 782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESlAAEI 861
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1868 DNKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKK--------WQAKIEGIRNKLKEKEGEVFTL 1939
Cdd:TIGR02168 862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSelrreleeLREKLAQLELRLEGLEVRIDNL 941
|
....*
gi 767975376 1940 TKQLN 1944
Cdd:TIGR02168 942 QERLS 946
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
162-981 |
2.67e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.15 E-value: 2.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 162 LRRENKRLKKKNEQlCQDIIDYQKQIDSQKETLL-----SRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQN 236
Cdd:TIGR02168 198 LERQLKSLERQAEK-AERYKELKAELRELELALLvlrleELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 237 QEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELtdllKSKNEEDDPIMVAVNAKVEEWKLI 316
Cdd:TIGR02168 277 SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEEL----ESKLDELAEELAELEEKLEELKEE 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 317 LSSKDDEIIEYQQMLHNLREKLK--NAQLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQR 394
Cdd:TIGR02168 353 LESLEAELEELEAELEELESRLEelEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 395 NKGASTlsQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLED----------AVVE 464
Cdd:TIGR02168 433 AELKEL--QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERlqenlegfseGVKA 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 465 IKNCKNQIK-IRDREIEILTKEiNKLELKISDFLDEN----------------EALRE----RVGLEPKTMIDLTEFRNS 523
Cdd:TIGR02168 511 LLKNQSGLSgILGVLSELISVD-EGYEAAIEAALGGRlqavvvenlnaakkaiAFLKQnelgRVTFLPLDSIKGTEIQGN 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 524 KHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQERGKRSATSGLTTEDLNLTENISQGDRISERKLdllSLKNMS 603
Cdd:TIGR02168 590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGV---ITGGSA 666
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 604 EAQSKNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDpdvkggetsliiPSLERLV 683
Cdd:TIGR02168 667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ------------ISALRKD 734
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 684 NAIESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQsegsnvvfkgi 763
Cdd:TIGR02168 735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE----------- 803
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 764 dlpdgIAPSSASIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKET----------W 833
Cdd:TIGR02168 804 -----ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELieeleseleaL 878
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 834 KTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKE 913
Cdd:TIGR02168 879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEA 958
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767975376 914 NEkqkNELLSMEAEVCEKIGCLQRfkemaifKIAALQKVvdNSVSLSELELANKQYNELTAKYRDILQ 981
Cdd:TIGR02168 959 LE---NKIEDDEEEARRRLKRLEN-------KIKELGPV--NLAAIEEYEELKERYDFLTAQKEDLTE 1014
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
27-743 |
6.04e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.00 E-value: 6.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 27 NLLISLSKVEVNELKSEKQEN------VIHLFRITQSLMKMK----AQEVELALEEVEKAGEEQAKFeNQLKTKVMKLEN 96
Cdd:TIGR02168 224 ELELALLVLRLEELREELEELqeelkeAEEELEELTAELQELeeklEELRLEVSELEEEIEELQKEL-YALANEISRLEQ 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 97 ELEMAQQSAggrdtRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQL 176
Cdd:TIGR02168 303 QKQILRERL-----ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEL 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 177 CQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEanEKIEVQNQEMRKNLEESVQEMEKMTDE 256
Cdd:TIGR02168 378 EEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK--KLEEAELKELQAELEELEEELEELQEE 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 257 YNRMKAIVHQTDNVIDQLKKENDHYQLQVQELT---DLLKSKNEEDDPIMVAVNAkVEEWKLILSSKDDEIIEyqqmLHN 333
Cdd:TIGR02168 456 LERLEEALEELREELEEAEQALDAAERELAQLQarlDSLERLQENLEGFSEGVKA-LLKNQSGLSGILGVLSE----LIS 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 334 LREKLKNAQLDADKSNvmaLQQGIQERDSQIKMLTEQVEQytKEMEKNTCIIEDLKNElQRNKGASTLSQQTHMKIQSTL 413
Cdd:TIGR02168 531 VDEGYEAAIEAALGGR---LQAVVVENLNAAKKAIAFLKQ--NELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLGVA 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 414 DILKEKTKEAER-----------TAELAEADAREKDKELVEALKRLKDY------------ESGVYGLEDAVVEIKNCKN 470
Cdd:TIGR02168 605 KDLVKFDPKLRKalsyllggvlvVDDLDNALELAKKLRPGYRIVTLDGDlvrpggvitggsAKTNSSILERRREIEELEE 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 471 QIKIRDREIEILTKEINKLELKISDFLDENEALRERvGLEPKTMIDLTEFRNSKHL-KQQQYRAENQILLKEIESLEEER 549
Cdd:TIGR02168 685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKE-LEELSRQISALRKDLARLEaEVEQLEERIAQLSKELTELEAEI 763
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 550 LDLKKKIRQMAQERGKRSATSGLTTEDLN-LTENISQGDRISerkldllslknmSEAQSKNEFLSRELIEKERDLERSRT 628
Cdd:TIGR02168 764 EELEERLEEAEEELAEAEAEIEELEAQIEqLKEELKALREAL------------DELRAELTLLNEEAANLRERLESLER 831
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 629 VIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVkggetslIIPSLERLVNAIESKNA--EGIFDASLHLKAQVD 706
Cdd:TIGR02168 832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE-------LESELEALLNERASLEEalALLRSELEELSEELR 904
|
730 740 750
....*....|....*....|....*....|....*..
gi 767975376 707 QLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHL 743
Cdd:TIGR02168 905 ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
114-853 |
1.51e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 60.47 E-value: 1.51e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 114 RNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQL----ALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQK---Q 186
Cdd:TIGR02169 176 LEELEEVEENIERLDLIIDEKRQQLERLRREREKAeryqALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEeleK 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 187 IDSQKETLLSRRGEDSDYRSQLSKKNYELIQylDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQ 266
Cdd:TIGR02169 256 LTEEISELEKRLEEIEQLLEELNKKIKDLGE--EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 267 TDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMV---AVNAKVEEWKlilsskdDEIIEYQQMLHNLREKLKNAQL 343
Cdd:TIGR02169 334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAeleEVDKEFAETR-------DELKDYREKLEKLKREINELKR 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 344 DADKSNVMALQQGIQERD--SQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTK 421
Cdd:TIGR02169 407 ELDRLQEELQRLSEELADlnAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELS 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 422 EAERTAELAEADAR---EKDKELVEALKRLKDYESGVYGLEDAVVEIK------------NCKNQIKIRDREIEILTKEI 486
Cdd:TIGR02169 487 KLQRELAEAEAQARaseERVRGGRAVEEVLKASIQGVHGTVAQLGSVGeryataievaagNRLNNVVVEDDAVAKEAIEL 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 487 NKlELKIS--DFLDENEALRERVGLEPKTM-------IDLTEFrnskhlkQQQYRAENQILLKE---IESLEEERlDLKK 554
Cdd:TIGR02169 567 LK-RRKAGraTFLPLNKMRDERRDLSILSEdgvigfaVDLVEF-------DPKYEPAFKYVFGDtlvVEDIEAAR-RLMG 637
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 555 KIRQMAQER-----------GKRSATSGLTTEDLNLTENISQGDRISERKLDLLSLKN--------MSEAQSKNEFLSRE 615
Cdd:TIGR02169 638 KYRMVTLEGelfeksgamtgGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSelrrienrLDELSQELSDASRK 717
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 616 LIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGmkeiLQAIKEMQKDPDVKGGETSLIIPSLERLVNAIESKNAEgif 695
Cdd:TIGR02169 718 IGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQE----IENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--- 790
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 696 daslhlkAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSllrqsegsNVVFKGIDLPDGIAPSSAS 775
Cdd:TIGR02169 791 -------SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ--------ELQEQRIDLKEQIKSIEKE 855
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767975376 776 IINSQNEyLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKETWKTESKTIKEEKRKLEDQVQQ 853
Cdd:TIGR02169 856 IENLNGK-KEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1640-1933 |
2.61e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 59.57 E-value: 2.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1640 LLVKLKKVSQDLERQREITELKVKEFENIKLQLQEnHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQaqKEANSRAP 1719
Cdd:COG1196 230 LLLKLRELEAELEELEAELEELEAELEELEAELAE-LEAELEELRLELEELELELEEAQAEEYELLAELA--RLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1720 TTTMRN----LVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRhTRELKTQVEDLN 1795
Cdd:COG1196 307 LEERRReleeRLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE-LAEAEEELEELA 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1796 ENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQgkpltdNKQSLIE 1875
Cdd:COG1196 386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA------ELEEEEE 459
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 767975376 1876 ELQRKVKKLENQLEGKVEEV-DLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKE 1933
Cdd:COG1196 460 ALLELLAELLEEAALLEAALaELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1347-1931 |
4.83e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 58.79 E-value: 4.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1347 WHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQN 1426
Cdd:COG1196 230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1427 EILNAAQKFEEATgsipdpslplpNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELR 1506
Cdd:COG1196 310 RRRELEERLEELE-----------EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1507 LRLpATAEREKLIAELGRKEMEPKSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEDLHILHH 1586
Cdd:COG1196 379 EEL-EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1587 RLELQADSSLNKFKQTAWDlmkqsptpvptnkhfirlAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFE 1666
Cdd:COG1196 458 EEALLELLAELLEEAALLE------------------AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1667 N-IKLQLQENHEDEVKKVKAEVEDL-----KYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQ 1740
Cdd:COG1196 520 RgLAGAVAVLIGVEAAYEAALEAALaaalqNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1741 QKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLN 1820
Cdd:COG1196 600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1821 DLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLtsglqgkpltdnKQSLIEELQRKVKKLENQLEGKVEEVDLKPM 1900
Cdd:COG1196 680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEER------------LEEELEEEALEEQLEAEREELLEELLEEEEL 747
|
570 580 590
....*....|....*....|....*....|.
gi 767975376 1901 KEKNAKEELIRWEEGKKWQAKIEGIRNKLKE 1931
Cdd:COG1196 748 LEEEALEELPEPPDLEELERELERLEREIEA 778
|
|
| DUF1633 |
pfam07794 |
Protein of unknown function (DUF1633); This family contains sequences derived from a group of ... |
1765-1941 |
2.50e-07 |
|
Protein of unknown function (DUF1633); This family contains sequences derived from a group of hypothetical proteins expressed by Arabidopsis thaliana. These sequences are highly similar and the region concerned is about 100 residues long.
Pssm-ID: 116408 [Multi-domain] Cd Length: 698 Bit Score: 56.43 E-value: 2.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1765 SATSQKEAHLNVQQivdrhTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQ----KKQKAYNKILRek 1840
Cdd:pfam07794 458 RAIREEDPHLGADQ-----DREVRFGAEGIVPGIERLKIELSTSKDLEKGYAEKIGFMEMEFGgleaDKQMARNQIHR-- 530
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1841 eeIDQENDELKRQIKRLTSGLQG--KPLTDNK-------QSLIEELQRK--VKKLENQLEGKVEEVDLK-PMKEKNAKEE 1908
Cdd:pfam07794 531 --LEEKKDELSKKVLDLTSIAQGakKAVHDAKvelaaayLKLLAGIKDKwvAKKEFTVLEGQAAEVESNlALIDQITKAA 608
|
170 180 190
....*....|....*....|....*....|...
gi 767975376 1909 LIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTK 1941
Cdd:pfam07794 609 IDLTLEKPRFQAEIDDLEARCKLKEVSDFTLSK 641
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
789-1371 |
3.64e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 56.30 E-value: 3.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 789 QELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKETWKTESKTIKEEKRKLED--QVQQDAIKVKEYNNLLN 866
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEakKKAEEAKKADEAKKKAE 1325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 867 ALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELER--QLRKENEKQKNELLSMEAEVCEKIGCLQRFKEMAIF 944
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEaaEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKK 1405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 945 KIAALQKVvdnsvslselELANKQYNELTAKYRDILQKDnmlvqrtsnlehleceniSLKEQVESINKELEItKEKLHTI 1024
Cdd:PTZ00121 1406 KADELKKA----------AAAKKKADEAKKKAEEKKKAD------------------EAKKKAEEAKKADEA-KKKAEEA 1456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1025 EQAWEQETKLGNESSMDKAKKSITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSlkqmEERNFELETKFAEL 1104
Cdd:PTZ00121 1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA----EEAKKADEAKKAEE 1532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1105 TKINLDAQKVEQMLRdelADSVSKAVsdadrqrilELEKNEMELKVE-VSKLREISDIARRQVEILNAQQQSRDKEVESL 1183
Cdd:PTZ00121 1533 AKKADEAKKAEEKKK---ADELKKAE---------ELKKAEEKKKAEeAKKAEEDKNMALRKAEEAKKAEEARIEEVMKL 1600
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1184 RMQLLDYQAQSDEKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHL 1263
Cdd:PTZ00121 1601 YEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEA 1680
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1264 RQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNM--ENKTLEMELKLKGLEELISTLKDTKGA 1341
Cdd:PTZ00121 1681 KKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKaeEAKKEAEEDKKKAEEAKKDEEEKKKIA 1760
|
570 580 590
....*....|....*....|....*....|
gi 767975376 1342 QKVINWHMKIEELRLQELKLNRELVKDKEE 1371
Cdd:PTZ00121 1761 HLKKEEEKKAEEIRKEKEAVIEEELDEEDE 1790
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1236-1857 |
4.24e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 55.71 E-value: 4.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1236 LRLEQKLDEKEQALYYARLEG-RNRAKHLRQTIQSLRRQFSGALplAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNM 1314
Cdd:COG1196 216 RELKEELKELEAELLLLKLRElEAELEELEAELEELEAELEELE--AELAELEAELEELRLELEELELELEEAQAEEYEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1315 ENKTLEMELKLKGLEELISTLKDTKGAQKVinwhmKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIV 1394
Cdd:COG1196 294 LAELARLEQDIARLEERRRELEERLEELEE-----ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1395 QQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATgsipdpslplpNQLEIALRKIKENIRIILETRATC 1474
Cdd:COG1196 369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL-----------ERLERLEEELEELEEALAELEEEE 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1475 KSLEEKLKEKESALRLAEQNILSRDKVINELRLRLpatAEREKLIAELGRKEMEPKSHHTLKIAHQtiANMQARLNQ-KE 1553
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEA---ALLEAALAELLEELAEAAARLLLLLEAE--ADYEGFLEGvKA 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1554 EVLKKYQRLLEKAREEQREIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQSPTPVPTnkhFIRLAEMEQTVAEQ 1633
Cdd:COG1196 513 ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT---FLPLDKIRARAALA 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1634 DDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKESQcLKSELQAQKE 1713
Cdd:COG1196 590 AALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA-GGSLTGGSRR 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1714 ANSRAptttmRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVED 1793
Cdd:COG1196 669 ELLAA-----LLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767975376 1794 LNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQK-------AYNKILREKEEIDQENDELKRQIKRL 1857
Cdd:COG1196 744 EEELLEEEALEELPEPPDLEELERELERLEREIEALGPvnllaieEYEELEERYDFLSEQREDLEEARETL 814
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
243-563 |
9.65e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.69 E-value: 9.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 243 LEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDpimvAVNAKVEEWKLILSSKDD 322
Cdd:TIGR02169 676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEE----KLKERLEELEEDLSSLEQ 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 323 EIIEYQQMLHNLREKLknAQLDADKSNVMALQQGIQ--ERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGAST 400
Cdd:TIGR02169 752 EIENVKSELKELEARI--EELEEDLHKLEEALNDLEarLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 401 LSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDRE-- 478
Cdd:TIGR02169 830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEle 909
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 479 --IEILTKEINKLELKISDFLDENEALRERVGL---EPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEE---RL 550
Cdd:TIGR02169 910 aqIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVlkrLD 989
|
330
....*....|...
gi 767975376 551 DLKKKIRQMAQER 563
Cdd:TIGR02169 990 ELKEKRAKLEEER 1002
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
21-661 |
9.86e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.56 E-value: 9.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 21 QEELADNLLISLSKVEVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFEnQLKTKVMKLENELEM 100
Cdd:COG1196 221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE-EAQAEEYELLAELAR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 101 AQQsaggrDTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDI 180
Cdd:COG1196 300 LEQ-----DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 181 IDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRM 260
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 261 KAIVHQTDNVIDQLKKENDHYQLQVQELTDLL---KSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEyqQMLHNLREK 337
Cdd:COG1196 455 EEEEEALLELLAELLEEAALLEAALAELLEELaeaAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA--GAVAVLIGV 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 338 LKNAQLDADKSNVMALQQGIQERDSQIKMLteqveqytkemekntciIEDLKnelQRNKGASTLSQQTHMKIQSTLDILK 417
Cdd:COG1196 533 EAAYEAALEAALAAALQNIVVEDDEVAAAA-----------------IEYLK---AAKAGRATFLPLDKIRARAALAAAL 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 418 EKTKEAERTAELAEadarekdkELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDREIEILTKEINKLELKISDFL 497
Cdd:COG1196 593 ARGAIGAAVDLVAS--------DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 498 DENEALRERVGLEPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQErgkrsatsgLTTEDL 577
Cdd:COG1196 665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ---------LEAERE 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 578 NLTENISQGDRISERKLDLLSLKNMSEAQsknefLSRELIEKERDLERSRTV----IAKF---QNKLKELVEENKQLEEG 650
Cdd:COG1196 736 ELLEELLEEEELLEEEALEELPEPPDLEE-----LERELERLEREIEALGPVnllaIEEYeelEERYDFLSEQREDLEEA 810
|
650
....*....|.
gi 767975376 651 MKEILQAIKEM 661
Cdd:COG1196 811 RETLEEAIEEI 821
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
206-559 |
1.04e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 54.29 E-value: 1.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 206 SQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQV 285
Cdd:TIGR02168 691 EKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL 770
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 286 QELTDLLKSKNEEddpiMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKS--NVMALQQGIQERDSQ 363
Cdd:TIGR02168 771 EEAEEELAEAEAE----IEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLerRIAATERRLEDLEEQ 846
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 364 IKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVE 443
Cdd:TIGR02168 847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 444 ALKRLKDYESGVYGLEDAVVEikncknQIKIRDREIEILTKEINKLELKISDFLDENEALRERVGlePKTMIDLTEFrns 523
Cdd:TIGR02168 927 LELRLEGLEVRIDNLQERLSE------EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG--PVNLAAIEEY--- 995
|
330 340 350
....*....|....*....|....*....|....*.
gi 767975376 524 khlkqQQYRAENQILLKEIESLEEERLDLKKKIRQM 559
Cdd:TIGR02168 996 -----EELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
963-1272 |
2.72e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.02 E-value: 2.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 963 ELANKQYNELTAKYRDILQKdnmLVQRTSNLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQEtklgnessmdK 1042
Cdd:COG1196 221 ELKELEAELLLLKLRELEAE---LEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA----------Q 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1043 AKKSITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDEL 1122
Cdd:COG1196 288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1123 ADSVSKAVS-----DADRQRILELEKNEMELKVEVSKL-REISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDE 1196
Cdd:COG1196 368 LEAEAELAEaeeelEELAEELLEALRAAAELAAQLEELeEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767975376 1197 KSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALyyARLEGRNRAKHLRQTIQSLRR 1272
Cdd:COG1196 448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE--ADYEGFLEGVKAALLLAGLRG 521
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1738-2454 |
2.78e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.22 E-value: 2.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1738 EKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTD 1817
Cdd:PTZ00121 1223 AKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKK 1302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1818 NLNDLNNELQKKQKAyNKILREKEEIDQENDELKRQI---KRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGKVEE 1894
Cdd:PTZ00121 1303 KADEAKKKAEEAKKA-DEAKKKAEEAKKKADAAKKKAeeaKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD 1381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1895 VDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKLKTTGMTVDQV 1974
Cdd:PTZ00121 1382 AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEE 1461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1975 LGIRALESEKELEELKKRNLDLENDILYMRAHQALPRDSVVEDLHLQNRYLQEKLHALEKQFSKDTYSKPSQNQISGIES 2054
Cdd:PTZ00121 1462 AKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKK 1541
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2055 DDHCQREQELQK-ENLKLSSE--NIELKFQLEQANKDLPRLKNQVRDLKE--------MCEFLKKEKAEVQRKLGHVRGS 2123
Cdd:PTZ00121 1542 AEEKKKADELKKaEELKKAEEkkKAEEAKKAEEDKNMALRKAEEAKKAEEarieevmkLYEEEKKMKAEEAKKAEEAKIK 1621
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2124 GRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKAsgiltsEKMANIEQENEKLKAELEKLKAhlgHQLSMHYESKTKGTE 2203
Cdd:PTZ00121 1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKA------EEENKIKAAEEAKKAEEDKKKA---EEAKKAEEDEKKAAE 1692
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2204 KIIAEN------ERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQfaESRGPQLEGADSKSWKSIVVTRM 2277
Cdd:PTZ00121 1693 ALKKEAeeakkaEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAE--EAKKDEEEKKKIAHLKKEEEKKA 1770
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2278 YETKlKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNeDLEQQIKILKHVPEGAETEQGLKRElqVLRLANHQLDKE 2357
Cdd:PTZ00121 1771 EEIR-KEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFAN-IIEGGKEGNLVINDSKEMEDSAIKE--VADSKNMQLEEA 1846
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2358 KAELIHQIEANKDQSGAESTIPDADQLKEKIKDLETQLKMSDLEKQhLKEEIKKLKKELENFDPSFFEEIEDlKYNYKEE 2437
Cdd:PTZ00121 1847 DAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEK-IDKDDIEREIPNNNMAGKNNDIIDD-KLDKDEY 1924
|
730
....*....|....*...
gi 767975376 2438 VKKNI-LLEEKVKKLSEQ 2454
Cdd:PTZ00121 1925 IKRDAeETREEIIKISKK 1942
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1284-1889 |
4.82e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 51.99 E-value: 4.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1284 EKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGaqkvinwhmKIEELRLQELKLNR 1363
Cdd:PRK03918 182 EKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE---------EIEELEKELESLEG 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1364 ELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQmawdqREVDLERQLDIFDRQQNEILNAAQKFEEatgsip 1443
Cdd:PRK03918 253 SKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAE-----EYIKLSEFYEEYLDELREIEKRLSRLEE------ 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1444 dpslpLPNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQnILSRDKVINELRLRLpATAEREKLIAELG 1523
Cdd:PRK03918 322 -----EINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEE-AKAKKEELERLKKRL-TGLTPEKLEKELE 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1524 RKEmepKSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREE----QREIVKKHEEDLhilhhrlelqadsslnkf 1599
Cdd:PRK03918 395 ELE---KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcGRELTEEHRKEL------------------ 453
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1600 kqtawdlmkqsptpvpTNKHFIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELK--VKEFENIKLQLQENHE 1677
Cdd:PRK03918 454 ----------------LEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKelAEQLKELEEKLKKYNL 517
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1678 DEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRaptttmrnlVERLKSQLALKEKQQKALSRALLELRAEMTA 1757
Cdd:PRK03918 518 EELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKK---------LAELEKKLDELEEELAELLKELEELGFESVE 588
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1758 AAEERIISATSQKEAHLNVQQIVDRHTRELK------TQVEDLNENLLKLKEALKTSKNRENSLTDNLND-----LNNEL 1826
Cdd:PRK03918 589 ELEERLKELEPFYNEYLELKDAEKELEREEKelkkleEELDKAFEELAETEKRLEELRKELEELEKKYSEeeyeeLREEY 668
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1827 QKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG-----KPLTDNKQSL--IEELQRKVKKLENQLE 1889
Cdd:PRK03918 669 LELSRELAGLRAELEELEKRREEIKKTLEKLKEELEErekakKELEKLEKALerVEELREKVKKYKALLK 738
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1780-2410 |
4.95e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 52.04 E-value: 4.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1780 VDRHTRELKTQVEDLNEnllKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTS 1859
Cdd:pfam15921 76 IERVLEEYSHQVKDLQR---RLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVH 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1860 GLQG-----KPLTDNKQSLIEELQRKVKKLENQLEG------KVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNK 1928
Cdd:pfam15921 153 ELEAakclkEDMLEDSNTQIEQLRKMMLSHEGVLQEirsilvDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTE 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1929 LKEKEGEVFTLTKQLNTLKD---------LFAKADK-EKLTLQRKLKTTGMTvDQVLGIRALESEKELEELKKRNLDLEN 1998
Cdd:pfam15921 233 ISYLKGRIFPVEDQLEALKSesqnkiellLQQHQDRiEQLISEHEVEITGLT-EKASSARSQANSIQSQLEIIQEQARNQ 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1999 DILYMRAHQALPR--DSVVEDLHLQNRYLQEKLHALEKQF------------SKDTYSKPSQN---QISGIESDDHcQRE 2061
Cdd:pfam15921 312 NSMYMRQLSDLEStvSQLRSELREAKRMYEDKIEELEKQLvlanselteartERDQFSQESGNlddQLQKLLADLH-KRE 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2062 QEL---QKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKE-KAEVQRKLGHVRGSGRSGKTIP----EL 2133
Cdd:pfam15921 391 KELsleKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMERQMAAIQGKNESLEKVSsltaQL 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2134 EKTIGLMKKVVEKVQRENEQLKKASGILTSEKMANIEQEN--EKLKAELEKLKAHLGHQLS--MHYESKTKGTEKIIAEN 2209
Cdd:pfam15921 471 ESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERaiEATNAEITKLRSRVDLKLQelQHLKNEGDHLRNVQTEC 550
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2210 ERLRKELKKETDAAEKLRIAKNNL------------EILNEKMTVQLEETGKRLQFAESRGPQlegaDSKSWKsivvTRM 2277
Cdd:pfam15921 551 EALKLQMAEKDKVIEILRQQIENMtqlvgqhgrtagAMQVEKAQLEKEINDRRLELQEFKILK----DKKDAK----IRE 622
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2278 YETKLKELETDIAK-------KNQSITDLKQ----LVKEATEREQKVNKYNEDLEQQIKILKHVPEGAETEQGlKRELQv 2346
Cdd:pfam15921 623 LEARVSDLELEKVKlvnagseRLRAVKDIKQerdqLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN-KLKMQ- 700
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767975376 2347 LRLANHQLDKEKAELIHQI----EANKDQSGAESTIP----DADQLKEKIKDLETQLKMSDLEKQHLKEEIK 2410
Cdd:pfam15921 701 LKSAQSELEQTRNTLKSMEgsdgHAMKVAMGMQKQITakrgQIDALQSKIQFLEEAMTNANKEKHFLKEEKN 772
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
269-1092 |
5.36e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.98 E-value: 5.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 269 NVIDQLKKENDHYQLQVQELTDLLKSKNEEddpiMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKlknaqldadks 348
Cdd:TIGR02168 232 LRLEELREELEELQEELKEAEEELEELTAE----LQELEEKLEELRLEVSELEEEIEELQKELYALANE----------- 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 349 nvmalqqgIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGAstlsqqthmkiqstLDILKEKTKEAERTAE 428
Cdd:TIGR02168 297 --------ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE--------------LAELEEKLEELKEELE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 429 LAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIrdrEIEILTKEINKLELKISDFLDENEALRERVG 508
Cdd:TIGR02168 355 SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN---EIERLEARLERLEDRRERLQQEIEELLKKLE 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 509 LEPKTMI--DLTEFRNSKHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQERGKRSAT-------SGLTTEDLNL 579
Cdd:TIGR02168 432 EAELKELqaELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLerlqenlEGFSEGVKAL 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 580 TENISQGDRISERKLDLLSLKNMSEAQ-------------SKNEFLSRELIE--KERDLERsRTVIAKFQNKLKELVEEN 644
Cdd:TIGR02168 512 LKNQSGLSGILGVLSELISVDEGYEAAieaalggrlqavvVENLNAAKKAIAflKQNELGR-VTFLPLDSIKGTEIQGND 590
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 645 KQLEEGMKEILQAIKEMQK-DPDVKGG-----ETSLIIPSLERLVNAIESKNAEG-IFDASLHLKAQVDQLTGRNEELRQ 717
Cdd:TIGR02168 591 REILKNIEGFLGVAKDLVKfDPKLRKAlsyllGGVLVVDDLDNALELAKKLRPGYrIVTLDGDLVRPGGVITGGSAKTNS 670
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 718 ELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQsEGSNVVFKGIDLPDGIAPSSASIiNSQNEYLIHLLQELENKEKK 797
Cdd:TIGR02168 671 SILERRREIEELEEKIEELEEKIAELEKALAELRK-ELEELEEELEQLRKELEELSRQI-SALRKDLARLEAEVEQLEER 748
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 798 LKNLEDSLEDYNRKFAvirhqqsllykEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKK 877
Cdd:TIGR02168 749 IAQLSKELTELEAEIE-----------ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE 817
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 878 ILAENSRKitvLQVNEKSLIRQYTTLVELERQLRKENEkqknELLSMEAEVCEkigcLQRFKEMAIFKIAALQKVVDnsV 957
Cdd:TIGR02168 818 EAANLRER---LESLERRIAATERRLEDLEEQIEELSE----DIESLAAEIEE----LEELIEELESELEALLNERA--S 884
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 958 SLSELELANKQYNELTAKYRDILQKdnmlvqrtsnLEHLECENISLKEQVESINKELEITKEKL-HTIEQAWEQ------ 1030
Cdd:TIGR02168 885 LEEALALLRSELEELSEELRELESK----------RSELRRELEELREKLAQLELRLEGLEVRIdNLQERLSEEysltle 954
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767975376 1031 ---ETKLGNESSMDKAKKSITnsdivSISKKITML---------EMKELNERQraEHCQKMYEHLRTSLKQMEE 1092
Cdd:TIGR02168 955 eaeALENKIEDDEEEARRRLK-----RLENKIKELgpvnlaaieEYEELKERY--DFLTAQKEDLTEAKETLEE 1021
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1584-1856 |
5.38e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.22 E-value: 5.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1584 LHHRLELQADSSLNKFKQTawdlmkQSPTPVPTNKHFIRlAEM--EQTVAEQDDSLSSLLVKLKKVSQDLERQREitelK 1661
Cdd:COG4913 182 LRRRLGIGSEKALRLLHKT------QSFKPIGDLDDFVR-EYMleEPDTFEAADALVEHFDDLERAHEALEDARE----Q 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1662 VKEFEniklQLQENHEdEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAptttmrnLVERLKSQLALKEKQQ 1741
Cdd:COG4913 251 IELLE----PIRELAE-RYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRA-------ELARLEAELERLEARL 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1742 KALSRALLELRAEMT-------AAAEERIISATSQKEAHLNVQQIVDRHTRELKTQV----EDLNENLLKLKEALKTSKN 1810
Cdd:COG4913 319 DALREELDELEAQIRgnggdrlEQLEREIERLERELEERERRRARLEALLAALGLPLpasaEEFAALRAEAAALLEALEE 398
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 767975376 1811 RENSLTDNLNDLNNELQKKQKAYNKILREKEE-------IDQENDELKRQIKR 1856
Cdd:COG4913 399 ELEALEEALAEAEAALRDLRRELRELEAEIASlerrksnIPARLLALRDALAE 451
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
87-739 |
8.22e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 51.66 E-value: 8.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 87 LKTKVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDREL----EDMEKELEKEKKVNEQLALRNEEAENENSKL 162
Cdd:pfam15921 236 LKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEItgltEKASSARSQANSIQSQLEIIQEQARNQNSMY 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 163 RRENKRLKKKNEQLCQDIIDYQKQIDSQKETLlsrrgedsdyRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKN 242
Cdd:pfam15921 316 MRQLSDLESTVSQLRSELREAKRMYEDKIEEL----------EKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLAD 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 243 LEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMvavnakveewklilsskdd 322
Cdd:pfam15921 386 LHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM------------------- 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 323 eiiEYQqmlhnlreklknaqldadksnvMALQQGIQERDSQIKMLTEQVEQyTKEMEKNtcIIEDLknelqrnkgasTLS 402
Cdd:pfam15921 447 ---ERQ----------------------MAAIQGKNESLEKVSSLTAQLES-TKEMLRK--VVEEL-----------TAK 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 403 QQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDREIEIL 482
Cdd:pfam15921 488 KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEIL 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 483 TKEI-NKLELKISDFLDENEALRERVGLEPKTMIDLTEFRNSKHLKQQQyRAENQILLKEIESLEEERLDLK-------K 554
Cdd:pfam15921 568 RQQIeNMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKK-DAKIRELEARVSDLELEKVKLVnagserlR 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 555 KIRQMAQERGKRSATSGLTTEDLNlteNISQGDRISERkldllSLKNMSEA-QSKNEFLSRELIEKERDLERSRTVIakf 633
Cdd:pfam15921 647 AVKDIKQERDQLLNEVKTSRNELN---SLSEDYEVLKR-----NFRNKSEEmETTTNKLKMQLKSAQSELEQTRNTL--- 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 634 qnklkelveenKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIESKNAEGIFDASLHLK---------AQ 704
Cdd:pfam15921 716 -----------KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKlsqelstvaTE 784
|
650 660 670
....*....|....*....|....*....|....*
gi 767975376 705 VDQLTGRNEELRQELRESRKEAINYSQQLAKANLK 739
Cdd:pfam15921 785 KNKMAGELEVLRSQERRLKEKVANMEVALDKASLQ 819
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1554-1863 |
9.65e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.09 E-value: 9.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1554 EVLKKYQRLLEKAREEQREIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQSptpvptnkhfIRLAEMEQTVAEQ 1633
Cdd:COG1196 210 EKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE----------AELEELRLELEEL 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1634 DDSLSSLLVKLKKVSQD---LERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQA 1710
Cdd:COG1196 280 ELELEEAQAEEYELLAElarLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1711 QKEANSRAPTTTmRNLVERLKSQLALKEKQQKALSRALLELRAEmtAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQ 1790
Cdd:COG1196 360 LAEAEEALLEAE-AELAEAEEELEELAEELLEALRAAAELAAQL--EELEEAEEALLERLERLEEELEELEEALAELEEE 436
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767975376 1791 VEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG 1863
Cdd:COG1196 437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
230-975 |
9.81e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.22 E-value: 9.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 230 EKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKEndhYQLQVQELTDLLKSKNEEDDPIMVAVNAK 309
Cdd:TIGR02169 219 EKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKR---LEEIEQLLEELNKKIKDLGEEEQLRVKEK 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 310 VEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKsnvmaLQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLK 389
Cdd:TIGR02169 296 IGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK-----LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLR 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 390 NELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDavveiknck 469
Cdd:TIGR02169 371 AELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEE--------- 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 470 nqikirdrEIEILTKEINKLELKISDFLDENEALRERVglepktmidltefrnskhlkqQQYRAENQILLKEIESLEEER 549
Cdd:TIGR02169 442 --------EKEDKALEIKKQEWKLEQLAADLSKYEQEL---------------------YDLKEEYDRVEKELSKLQREL 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 550 LDLKKKIRQMAQERGKRSATSGLTTEDLN-LTENISQGDRISER-----------KLDLLSLKNMSEAQSKNEFLSRELI 617
Cdd:TIGR02169 493 AEAEAQARASEERVRGGRAVEEVLKASIQgVHGTVAQLGSVGERyataievaagnRLNNVVVEDDAVAKEAIELLKRRKA 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 618 --------EKERDLERSRTVIAK--FQNKLKELVEENKQLEEGMKEILQ---AIKEMQKDPDVKGG------ETSLIIPS 678
Cdd:TIGR02169 573 gratflplNKMRDERRDLSILSEdgVIGFAVDLVEFDPKYEPAFKYVFGdtlVVEDIEAARRLMGKyrmvtlEGELFEKS 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 679 LERLVNAIESKNAEGI----FDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQSE 754
Cdd:TIGR02169 653 GAMTGGSRAPRGGILFsrsePAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE 732
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 755 GSNvvfkgidlpdgiapssASIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKetwk 834
Cdd:TIGR02169 733 EKL----------------KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR---- 792
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 835 teSKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKEN 914
Cdd:TIGR02169 793 --IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL 870
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767975376 915 EKQKNELLSMEaevcEKIGCLQRFKEMAIFKIAALQKVVDNSVslSELELANKQYNELTAK 975
Cdd:TIGR02169 871 EELEAALRDLE----SRLGDLKKERDELEAQLRELERKIEELE--AQIEKKRKRLSELKAK 925
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1787-2396 |
1.11e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.21 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1787 LKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGlqgkpl 1866
Cdd:TIGR02168 230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ------ 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1867 tdnkqslIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELirweegKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTL 1946
Cdd:TIGR02168 304 -------KQILRERLANLERQLEELEAQLEELESKLDELAEEL------AELEEKLEELKEELESLEAELEELEAELEEL 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1947 KDLFAKADKEKLTLQRKLKTTGMTVDQvlgiralesekeleelkkrnldLENDILYMRAHqalprdsvVEDLHLQNRYLQ 2026
Cdd:TIGR02168 371 ESRLEELEEQLETLRSKVAQLELQIAS----------------------LNNEIERLEAR--------LERLEDRRERLQ 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2027 EKLHALEKQFSKDtyskpsqnqisgiESDDHCQREQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFL 2106
Cdd:TIGR02168 421 QEIEELLKKLEEA-------------ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2107 KKEKAEVQRKLGHVRGSGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMANIEQEN-EKLKAELEKLKA 2185
Cdd:TIGR02168 488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENlNAAKKAIAFLKQ 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2186 HLGHQLSMHYESKTKGTEKIIAENERLRKE------LKKETDAAEKLRIAKNNLeiLNEKMTVQLEETG----KRLQFAE 2255
Cdd:TIGR02168 568 NELGRVTFLPLDSIKGTEIQGNDREILKNIegflgvAKDLVKFDPKLRKALSYL--LGGVLVVDDLDNAlelaKKLRPGY 645
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2256 ----------SRGPQLEGADSKSWKSIVVTRM----YETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLE 2321
Cdd:TIGR02168 646 rivtldgdlvRPGGVITGGSAKTNSSILERRReieeLEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS 725
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767975376 2322 QQIKILKHVPEGAETEQglkrelQVLRLANHQLDKEKAELIHQIEANKDQSGAEStiPDADQLKEKIKDLETQLK 2396
Cdd:TIGR02168 726 RQISALRKDLARLEAEV------EQLEERIAQLSKELTELEAEIEELEERLEEAE--EELAEAEAEIEELEAQIE 792
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1817-2402 |
1.15e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.83 E-value: 1.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1817 DNLNDLNNELQKKQKAYNKILREKEEIDqenDELKRQIKRLTSGLQgkpLTDNKQSLIEELQRKVKKLENQLEgKVEEvd 1896
Cdd:PRK03918 165 KNLGEVIKEIKRRIERLEKFIKRTENIE---ELIKEKEKELEEVLR---EINEISSELPELREELEKLEKEVK-ELEE-- 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1897 LKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLfaKADKEKLTLQRKLKTTGMTVDQVLG 1976
Cdd:PRK03918 236 LKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL--KEKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1977 IRALESEKELEELKKRNLDLENDilymrahqalprDSVVEDLHLQNRYLQEKLHALEKQFSKDTYSKPSQNQISGIESDD 2056
Cdd:PRK03918 314 KRLSRLEEEINGIEERIKELEEK------------EERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRL 381
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2057 HCQREQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEV---QRKLGHVRGSGRSGKTIPEL 2133
Cdd:PRK03918 382 TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCpvcGRELTEEHRKELLEEYTAEL 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2134 EKTIGLMKKVVEKVQRENEQLKKASGILTSE-KMANIEQENEKLKAELEKLKAHLGHQLsmhyESKTKGTEKIIAENERL 2212
Cdd:PRK03918 462 KRIEKELKEIEEKERKLRKELRELEKVLKKEsELIKLKELAEQLKELEEKLKKYNLEEL----EKKAEEYEKLKEKLIKL 537
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2213 RKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQFAESRGPQLEGADSKSWKSIVVTRMYETKLKELETDIAKK 2292
Cdd:PRK03918 538 KGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELERE 617
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2293 NQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHVPEGAETEQ------GLKRELQVLRLANHQLDKEKAELIHQIE 2366
Cdd:PRK03918 618 EKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEElreeylELSRELAGLRAELEELEKRREEIKKTLE 697
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 767975376 2367 ANKDQSGA-----------ESTIPDADQLKEKIKDLETQLKMSDLEK 2402
Cdd:PRK03918 698 KLKEELEErekakkeleklEKALERVEELREKVKKYKALLKERALSK 744
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
608-927 |
1.15e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.09 E-value: 1.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 608 KNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIE 687
Cdd:COG1196 226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 688 sknaegifdaslHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQSegsnvvfkgidlpd 767
Cdd:COG1196 306 ------------RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE-------------- 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 768 giapssasiinsqneyLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKEtwktESKTIKEEKRKL 847
Cdd:COG1196 360 ----------------LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE----AEEALLERLERL 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 848 EDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKENEKQKNELLSMEAE 927
Cdd:COG1196 420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1012-1805 |
3.29e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.75 E-value: 3.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1012 KELEITKEKLHTIEQAWEQETKLGNESSMDKAKKSITNSDIVSISKKITmlEMKELNERQRAEHCQKMYEHLRTSlkqme 1091
Cdd:PTZ00121 1077 KDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAE--DARKAEEARKAEDARKAEEARKAE----- 1149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1092 ernfelETKFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILELEKNEMELKVEVSKLREIsdiARRQVEILNA 1171
Cdd:PTZ00121 1150 ------DAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEE---ERKAEEARKA 1220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1172 QQQSRDKEVESLrmqllDYQAQSDEKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALYY 1251
Cdd:PTZ00121 1221 EDAKKAEAVKKA-----EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEA 1295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1252 ARLEGRNRAKHLRQTIQSLRRqfsgalplAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEEL 1331
Cdd:PTZ00121 1296 KKAEEKKKADEAKKKAEEAKK--------ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE 1367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1332 ISTLKDTKGAQKVINWHMKIEELRLQElklnrELVKDKEEIKylnniiseyeRTISSLEEEIVQQNKFHEERQMAWDQRE 1411
Cdd:PTZ00121 1368 AAEKKKEEAKKKADAAKKKAEEKKKAD-----EAKKKAEEDK----------KKADELKKAAAAKKKADEAKKKAEEKKK 1432
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1412 VDLERQLDIFDRQQNEilnAAQKFEEAtgsipdpslplpnqleialrKIKENIRIILETRATCKSLEEKLKEKESALRLA 1491
Cdd:PTZ00121 1433 ADEAKKKAEEAKKADE---AKKKAEEA--------------------KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAK 1489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1492 EQNILSRDKViNELRlrlpaTAEREKLIAELGRKEMEPKSHHTLKIAHQTIANMQARLNQ---KEEVLKKYQRLLEKARE 1568
Cdd:PTZ00121 1490 KKAEEAKKKA-DEAK-----KAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEekkKADELKKAEELKKAEEK 1563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1569 EQREIVKKHEEDLHILHHRLELQADSSlnkfKQTAWDLMKQSPTPVPTNKHFIRLAEMEQTVAEQddslssllvklkkVS 1648
Cdd:PTZ00121 1564 KKAEEAKKAEEDKNMALRKAEEAKKAE----EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEE-------------LK 1626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1649 QDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKEsQCLKSELQAQKEANSRAPTTTMRNLVE 1728
Cdd:PTZ00121 1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAE-EAKKAEEDEKKAAEALKKEAEEAKKAE 1705
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767975376 1729 RLKSQLALKEKQQKALSRALLELRAEMTAAAEERiiSATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEAL 1805
Cdd:PTZ00121 1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA--EEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
356-752 |
4.01e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.30 E-value: 4.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 356 GIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRnkgastlsqqthmkiqstldiLKEKTKEAERTAELAEadaR 435
Cdd:TIGR02169 164 GVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLER---------------------LRREREKAERYQALLK---E 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 436 EKDKELVEALKRLKDYESgvygledavveikncknQIKIRDREIEILTKEINKLELKISDFLDENEALRERVGLEPKTMI 515
Cdd:TIGR02169 220 KREYEGYELLKEKEALER-----------------QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 516 DLTEfrnskhlkqqqyrAENQILLKEIESLEEERLDLKKKIRQMAQERGKRSATSGLTTEDLnltenisqgDRISERKLD 595
Cdd:TIGR02169 283 DLGE-------------EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEI---------DKLLAEIEE 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 596 LlsLKNMSEAQSKNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLI 675
Cdd:TIGR02169 341 L--EREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRL 418
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767975376 676 IPSLERLVNAIesknaEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQ 752
Cdd:TIGR02169 419 SEELADLNAAI-----AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1373-2186 |
4.44e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 48.96 E-value: 4.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1373 KYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKfeeatgsipdpslplPNQ 1452
Cdd:pfam15921 74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRR---------------ESQ 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1453 LEIALRKIKENIRIILETRATCKslEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAE-------REKLIAELGRK 1525
Cdd:pfam15921 139 SQEDLRNQLQNTVHELEAAKCLK--EDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEasgkkiyEHDSMSTMHFR 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1526 EMEPKSHHTLKIAHQTIANMQARLNQKEEVLK--------KYQRLLEKAREEQREIVKKHEEDLHILHHRLElQADSSLN 1597
Cdd:pfam15921 217 SLGSAISKILRELDTEISYLKGRIFPVEDQLEalksesqnKIELLLQQHQDRIEQLISEHEVEITGLTEKAS-SARSQAN 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1598 KFKQTAWDLMKQSPTpvpTNKHFIR-LAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQE-- 1674
Cdd:pfam15921 296 SIQSQLEIIQEQARN---QNSMYMRqLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQes 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1675 -NHEDEVKKVkaevedlkyLLDQSQKEsqclkSELQAQKEANSRAPTTTMRN--LVERLKSQLALKEKQQKALSRALLEL 1751
Cdd:pfam15921 373 gNLDDQLQKL---------LADLHKRE-----KELSLEKEQNKRLWDRDTGNsiTIDHLRRELDDRNMEVQRLEALLKAM 438
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1752 RAEMTAAAEERIISATSQKEAHLNVQQivdrhtreLKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQK 1831
Cdd:pfam15921 439 KSECQGQMERQMAAIQGKNESLEKVSS--------LTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER 510
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1832 AynkilrekeeidqendelkrqikrltsglqgkpltdnkqslIEELQRKVKKLENQLEGKVEEVDlkpmKEKNAKEELir 1911
Cdd:pfam15921 511 A-----------------------------------------IEATNAEITKLRSRVDLKLQELQ----HLKNEGDHL-- 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1912 weegKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADK-------EKLTLQRKLKTTGMTVdQVLGIRALESEK 1984
Cdd:pfam15921 544 ----RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRtagamqvEKAQLEKEINDRRLEL-QEFKILKDKKDA 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1985 ELEELKKRNLDLENDILYMrAHQALPRDSVVEDLHlqnrylQEKLHALEKqfskdtySKPSQNQISGIESDdhcqreQEL 2064
Cdd:pfam15921 619 KIRELEARVSDLELEKVKL-VNAGSERLRAVKDIK------QERDQLLNE-------VKTSRNELNSLSED------YEV 678
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2065 QKENLKLSSENIE-----LKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEVQRKLGHVRGSgrsgktIPELEKTIGL 2139
Cdd:pfam15921 679 LKRNFRNKSEEMEtttnkLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQ------IDALQSKIQF 752
|
810 820 830 840
....*....|....*....|....*....|....*....|....*..
gi 767975376 2140 MKKVVEKVQRENEQLKKASGILtSEKMANIEQENEKLKAELEKLKAH 2186
Cdd:pfam15921 753 LEEAMTNANKEKHFLKEEKNKL-SQELSTVATEKNKMAGELEVLRSQ 798
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
75-486 |
4.72e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.90 E-value: 4.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 75 KAGEEQAKFENQLKTKVMKLENELEMaqqsaggrdtrfLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEE 154
Cdd:TIGR02168 684 EKIEELEEKIAELEKALAELRKELEE------------LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 155 AENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEV 234
Cdd:TIGR02168 752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER 831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 235 QNQEMRKNLEESVQEMEKMTDEynrMKAIVHQtdnvIDQLKKENDHYQLQVQELTDLLKSKNEEddpiMVAVNAKVEEWK 314
Cdd:TIGR02168 832 RIAATERRLEDLEEQIEELSED---IESLAAE----IEELEELIEELESELEALLNERASLEEA----LALLRSELEELS 900
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 315 LILSSKDDEIIEYQQMLHNLREKLKNAQLDadksnvmaLQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQR 394
Cdd:TIGR02168 901 EELRELESKRSELRRELEELREKLAQLELR--------LEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARR 972
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 395 NkgastlsqqthmkiqstLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIkncknqiki 474
Cdd:TIGR02168 973 R-----------------LKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI--------- 1026
|
410
....*....|..
gi 767975376 475 rDREIEILTKEI 486
Cdd:TIGR02168 1027 -DREARERFKDT 1037
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1733-2403 |
7.28e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 48.43 E-value: 7.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1733 QLALKEKQQKALSRALLELRAE----MTAAAEERIISATSQKE------AHLNVQQIVDRHTRELKTQVEDLNENLLKLK 1802
Cdd:TIGR00618 180 QLALMEFAKKKSLHGKAELLTLrsqlLTLCTPCMPDTYHERKQvlekelKHLREALQQTQQSHAYLTQKREAQEEQLKKQ 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1803 EALKTSKNRENSLTDNLNDLNN-----ELQKKQKAYNKILREKEEIDQE----NDELKRQIKRLTSGLQGKPLTDNKQSL 1873
Cdd:TIGR00618 260 QLLKQLRARIEELRAQEAVLEEtqeriNRARKAAPLAAHIKAVTQIEQQaqriHTELQSKMRSRAKLLMKRAAHVKQQSS 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1874 IEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLK----------EKEGEVFTLTKQL 1943
Cdd:TIGR00618 340 IEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQslckeldilqREQATIDTRTSAF 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1944 NTLKDLFAKADKE-----KLTLQRKLKTTGMTVDQVLGIRALESEKELEELKKRNLDLENDILYMRAHQALPRDSVVEDL 2018
Cdd:TIGR00618 420 RDLQGQLAHAKKQqelqqRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLEL 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2019 HLQNRYLQEKLHALEKQFSKDTYSKPSQNQISGIEsDDHCQREQELQKENLKLSSEN---IELKFQLEQANKDLPRLKNQ 2095
Cdd:TIGR00618 500 QEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGE-QTYAQLETSEEDVYHQLTSERkqrASLKEQMQEIQQSFSILTQC 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2096 VRDLKEMCEFLKKEKAEVQrklghvrgsgrsgktiPELEKTIGLMKKVVEKVQRENEQLKKASGIL-TSEKMANIEQENE 2174
Cdd:TIGR00618 579 DNRSKEDIPNLQNITVRLQ----------------DLTEKLSEAEDMLACEQHALLRKLQPEQDLQdVRLHLQQCSQELA 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2175 KLKAELEKLKAHLGHQLSMHYESKTKGTEKIIAEneRLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGK-RLQF 2253
Cdd:TIGR00618 643 LKLTALHALQLTLTQERVREHALSIRVLPKELLA--SRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEyDREF 720
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2254 AE------SRGPQLEGADSKSWKSI-VVTRMYETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKI 2326
Cdd:TIGR00618 721 NEienassSLGSDLAAREDALNQSLkELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHL 800
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767975376 2327 LKHVPegAETEQGLKRELQVLRLANHQLDKEKAELIHQIEANKDQSGAESTI--PDADQLKEKIKDLETQLKMSDLEKQ 2403
Cdd:TIGR00618 801 LKTLE--AEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQllKYEECSKQLAQLTQEQAKIIQLSDK 877
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
967-1696 |
1.25e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.74 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 967 KQYNELTAKYRDiLQKDNMLVQRTSNLEHLEceniSLKEQVESINKELEITKEKLHTIEQAWEQetkLGNESSMDKAKKS 1046
Cdd:TIGR02168 213 ERYKELKAELRE-LELALLVLRLEELREELE----ELQEELKEAEEELEELTAELQELEEKLEE---LRLEVSELEEEIE 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1047 ITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDELADSV 1126
Cdd:TIGR02168 285 ELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1127 SKAV-----SDADRQRILELEKNEMELKVEVSKLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQ------SD 1195
Cdd:TIGR02168 365 AELEelesrLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKelqaelEE 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1196 EKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALyyARLEGRNRAkhLRQTIQSlRRQFS 1275
Cdd:TIGR02168 445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ--ENLEGFSEG--VKALLKN-QSGLS 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1276 GALPLAQQ-----EKFSKTM------------IQLQNDKLKIMQEMKN-----------SQQEHRNMENKTLEMELKLKG 1327
Cdd:TIGR02168 520 GILGVLSElisvdEGYEAAIeaalggrlqavvVENLNAAKKAIAFLKQnelgrvtflplDSIKGTEIQGNDREILKNIEG 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1328 LEELISTL-KDTKGAQKVIN---WHMKI-------EELRLQELKLNRELVKD------------------------KEEI 1372
Cdd:TIGR02168 600 FLGVAKDLvKFDPKLRKALSyllGGVLVvddldnaLELAKKLRPGYRIVTLDgdlvrpggvitggsaktnssilerRREI 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1373 KYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQ---REVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPL 1449
Cdd:TIGR02168 680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQlrkELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1450 PNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAER-EKLIAELGRKEME 1528
Cdd:TIGR02168 760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERlESLERRIAATERR 839
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1529 pkshhtLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVK---KHEEDLHILHHRLElQADSSLNKFKQtawd 1605
Cdd:TIGR02168 840 ------LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNeraSLEEALALLRSELE-ELSEELRELES---- 908
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1606 lmkqsptpvptnkhfiRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQRE-ITELKVKEFENIkLQLQENHEDEVKKVK 1684
Cdd:TIGR02168 909 ----------------KRSELRRELEELREKLAQLELRLEGLEVRIDNLQErLSEEYSLTLEEA-EALENKIEDDEEEAR 971
|
810
....*....|..
gi 767975376 1685 AEVEDLKYLLDQ 1696
Cdd:TIGR02168 972 RRLKRLENKIKE 983
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
34-428 |
1.33e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.83 E-value: 1.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 34 KVEVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMaqqsaggrdtrfl 113
Cdd:PTZ00121 1565 KAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE------------- 1631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 114 RNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKqidsqKET 193
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-----AEE 1706
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 194 LLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKievQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQ 273
Cdd:PTZ00121 1707 LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK---KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 274 -LKKENDHYQLQVQELTDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQMlhnLREKLKNAQLDADKSNVMA 352
Cdd:PTZ00121 1784 eLDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNM---QLEEADAFEKHKFNKNNEN 1860
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767975376 353 LQQGIQERDSQIKmlTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAE 428
Cdd:PTZ00121 1861 GEDGNKEADFNKE--KDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETRE 1934
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1147-1957 |
1.36e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.37 E-value: 1.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1147 ELKVEVSKLREISDIARRQVEILNAQQQSRDKEVESL---RMQLLDYQAQSDEKS------LIAKLHQHNVSLQLSEATA 1217
Cdd:TIGR02169 167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLrreREKAERYQALLKEKReyegyeLLKEKEALERQKEAIERQL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1218 LGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRRQFSGALplAQQEKFSKTMIQLQNDK 1297
Cdd:TIGR02169 247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLE--RSIAEKERELEDAEERL 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1298 LKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKVinwhmKIEELRLQELKLNRELVKDKEEIKYLNN 1377
Cdd:TIGR02169 325 AKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA-----ELEEVDKEFAETRDELKDYREKLEKLKR 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1378 IISEYERTISSLEEEIVQqnkfheeRQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPLpNQLEIAL 1457
Cdd:TIGR02169 400 EINELKRELDRLQEELQR-------LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADL-SKYEQEL 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1458 RKIKENIRIILETRatcKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAereKLIAELGRKEMEpkshHTLKI 1537
Cdd:TIGR02169 472 YDLKEEYDRVEKEL---SKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVH---GTVAQLGSVGER----YATAI 541
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1538 AHQTIANMQARLNQKEEVLKKYQRLLeKAREEQREI------VKKHEEDLHILHhrlelqadssLNKFKQTAWDLMKQSP 1611
Cdd:TIGR02169 542 EVAAGNRLNNVVVEDDAVAKEAIELL-KRRKAGRATflplnkMRDERRDLSILS----------EDGVIGFAVDLVEFDP 610
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1612 TPVPTNKHFIRlaemEQTVAEQDDSLSSLLVKLKKVSQD---LERQREITELKVKEFENIKLQLQEnhEDEVKKVKAEVE 1688
Cdd:TIGR02169 611 KYEPAFKYVFG----DTLVVEDIEAARRLMGKYRMVTLEgelFEKSGAMTGGSRAPRGGILFSRSE--PAELQRLRERLE 684
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1689 DLKYLLDQSQKESQCLKSELQAQKEANSRAP--TTTMRNLVERL-------KSQLALKEKQQKALSRALLELRAEMTAAA 1759
Cdd:TIGR02169 685 GLKRELSSLQSELRRIENRLDELSQELSDASrkIGEIEKEIEQLeqeeeklKERLEELEEDLSSLEQEIENVKSELKELE 764
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1760 EERiisATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILRE 1839
Cdd:TIGR02169 765 ARI---EELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ 841
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1840 KEEIDQENDELKRQIkrltsglqgkpltDNKQSLIEELQRKVKKLENQLEgkveevDLKPMKEKNAKEELIRWEEGKKWQ 1919
Cdd:TIGR02169 842 RIDLKEQIKSIEKEI-------------ENLNGKKEELEEELEELEAALR------DLESRLGDLKKERDELEAQLRELE 902
|
810 820 830
....*....|....*....|....*....|....*...
gi 767975376 1920 AKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEK 1957
Cdd:TIGR02169 903 RKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPK 940
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
788-1525 |
1.79e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.97 E-value: 1.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 788 LQELENKEKKLKNLEDSLEDYNRKFAVIRHQ--QSLLYKEYLSEKET-----WKTESKTIKEEKRKLEDQVQQDAIKVKE 860
Cdd:TIGR02168 178 ERKLERTRENLDRLEDILNELERQLKSLERQaeKAERYKELKAELRElelalLVLRLEELREELEELQEELKEAEEELEE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 861 YNNLLNALQMDSDEMKKILAENSRKITVLQvneKSLIRQYTTLVELERQLRKENEKQKNeLLSMEAEVCEKIGCLQRFKE 940
Cdd:TIGR02168 258 LTAELQELEEKLEELRLEVSELEEEIEELQ---KELYALANEISRLEQQKQILRERLAN-LERQLEELEAQLEELESKLD 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 941 MAIFKIAALQKVVDnsVSLSELELANKQYNELTAKYRDILQKdnmLVQRTSNLEHLECENISLKEQVESINKELEITKEK 1020
Cdd:TIGR02168 334 ELAEELAELEEKLE--ELKEELESLEAELEELEAELEELESR---LEELEEQLETLRSKVAQLELQIASLNNEIERLEAR 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1021 LHTIEQAWE--QETKLGNESSMDKAKKSITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQME------- 1091
Cdd:TIGR02168 409 LERLEDRRErlQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAErelaqlq 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1092 ------ERNFELETKFAELTKINLDAQKVEQMLRDELADSVS------KAVSDADRQRILELE-KNEMELKVEVSKLRE- 1157
Cdd:TIGR02168 489 arldslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvdegyeAAIEAALGGRLQAVVvENLNAAKKAIAFLKQn 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1158 ---------ISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSdEKSLIAKLHQHNVSLQLSEATALGK-------- 1220
Cdd:TIGR02168 569 elgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKL-RKALSYLLGGVLVVDDLDNALELAKklrpgyri 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1221 -------------------------------LESITSKLQKMEAYNLRLEQKLDEKEQALYyarlEGRNRAKHLRQTIQS 1269
Cdd:TIGR02168 648 vtldgdlvrpggvitggsaktnssilerrreIEELEEKIEELEEKIAELEKALAELRKELE----ELEEELEQLRKELEE 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1270 LRRQFSGALP-----LAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKV 1344
Cdd:TIGR02168 724 LSRQISALRKdlarlEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1345 I--NWHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFD 1422
Cdd:TIGR02168 804 AldELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1423 RQQNEILNAAQKFEEATGSIpdpslplpNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESAL--RLAEQNILSRDK 1500
Cdd:TIGR02168 884 SLEEALALLRSELEELSEEL--------RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLqeRLSEEYSLTLEE 955
|
810 820
....*....|....*....|....*
gi 767975376 1501 VINELRLRLPATAEREKLIAELGRK 1525
Cdd:TIGR02168 956 AEALENKIEDDEEEARRRLKRLENK 980
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1622-1947 |
2.11e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.98 E-value: 2.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1622 RLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEvKKVKAEVEDLKYLLDQSQKES 1701
Cdd:TIGR02169 675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE-EKLKERLEELEEDLSSLEQEI 753
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1702 QCLKSELQ--AQKEANSRAPTTTMRNLVERLKSQLALKEKQQK-ALSRALLELRAEMTAAAE--ERIISATSQKEAHLN- 1775
Cdd:TIGR02169 754 ENVKSELKelEARIEELEEDLHKLEEALNDLEARLSHSRIPEIqAELSKLEEEVSRIEARLReiEQKLNRLTLEKEYLEk 833
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1776 -----VQQIVDRHTR--ELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQEND 1848
Cdd:TIGR02169 834 eiqelQEQRIDLKEQikSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIE 913
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1849 ELKRQIKRLTSGLQG-----KPLTDNKQSLIEE---------LQRKVKKLENQLEgKVEEVDLKPMKEknakeelirWEE 1914
Cdd:TIGR02169 914 KKRKRLSELKAKLEAleeelSEIEDPKGEDEEIpeeelsledVQAELQRVEEEIR-ALEPVNMLAIQE---------YEE 983
|
330 340 350
....*....|....*....|....*....|...
gi 767975376 1915 GKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLK 1947
Cdd:TIGR02169 984 VLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1453-1958 |
2.13e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.60 E-value: 2.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1453 LEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPAT-AEREKLIAELGRKEMEPKS 1531
Cdd:PRK03918 160 YENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELrEELEKLEKEVKELEELKEE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1532 HHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEdlhilhHRLELQADSSLNKFKqtawdlmkqsp 1611
Cdd:PRK03918 240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE------LKEKAEEYIKLSEFY----------- 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1612 tpvptNKHFIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITElKVKEFENIKLQLQENHE--DEVKKVKAEVED 1689
Cdd:PRK03918 303 -----EEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKK-KLKELEKRLEELEERHElyEEAKAKKEELER 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1690 LKYLLDQSQKESqcLKSELQAQKEANsraptTTMRNLVERLKSQLALKEKQQKALSRALLELR-AEMTAAAEERIISATS 1768
Cdd:PRK03918 377 LKKRLTGLTPEK--LEKELEELEKAK-----EEIEEEISKITARIGELKKEIKELKKAIEELKkAKGKCPVCGRELTEEH 449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1769 QKEahlnvqqIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDN--------LNDLNNELQKKQKAYN-----K 1835
Cdd:PRK03918 450 RKE-------LLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKEseliklkeLAEQLKELEEKLKKYNleeleK 522
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1836 ILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKE------------- 1902
Cdd:PRK03918 523 KAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEEleerlkelepfyn 602
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767975376 1903 -----KNAKEEL-IRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKL 1958
Cdd:PRK03918 603 eylelKDAEKELeREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEEL 664
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
1678-1887 |
2.25e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 46.83 E-value: 2.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1678 DEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNL-VERLKSQLALKEKQQKALSRALLELRAEMT 1756
Cdd:PRK11281 73 DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLsLRQLESRLAQTLDQLQNAQNDLAEYNSQLV 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1757 AA--AEERIISATSQkeahlNVQQivdrhTRELKTQVEDLNENLLKLKEALKTSKNRENSLTdnlnDLNNELQKKQKAYN 1834
Cdd:PRK11281 153 SLqtQPERAQAALYA-----NSQR-----LQQIRNLLKGGKVGGKALRPSQRVLLQAEQALL----NAQNDLQRKSLEGN 218
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 767975376 1835 KILREKEEidQENDELKRQIKRLTSGLQgkpltdNKQSLI-----EELQRKVKKLENQ 1887
Cdd:PRK11281 219 TQLQDLLQ--KQRDYLTARIQRLEHQLQ------LLQEAInskrlTLSEKTVQEAQSQ 268
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
153-734 |
2.62e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 46.35 E-value: 2.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 153 EEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRgedsdyrsqlskknyeliqylDEIQTLTEAneki 232
Cdd:pfam10174 112 ELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARD---------------------ESIKKLLEM---- 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 233 eVQNQEMRKNLEESVQEMEKMTDEYnrmKAIVHQTDNVIDQLKKENDHyqlqvqeLTDLLKSKNEeddpiMVAVNAKVEE 312
Cdd:pfam10174 167 -LQSKGLPKKSGEEDWERTRRIAEA---EMQLGHLEVLLDQKEKENIH-------LREELHRRNQ-----LQPDPAKTKA 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 313 WKLILSSKDDEIIEYQQMLHNLREklknaQLDADKSNVMAlqqGIQERDSQIKMLtEQVEQYTKEMEKNtciIEDLKNEL 392
Cdd:pfam10174 231 LQTVIEMKDTKISSLERNIRDLED-----EVQMLKTNGLL---HTEDREEEIKQM-EVYKSHSKFMKNK---IDQLKQEL 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 393 QRnKGASTLSQQTHMKIQST--------LDILKEKTKEAERTAEL--AEADA-----REKDKELVEALKRLKDYESGVYG 457
Cdd:pfam10174 299 SK-KESELLALQTKLETLTNqnsdckqhIEVLKESLTAKEQRAAIlqTEVDAlrlrlEEKESFLNKKTKQLQDLTEEKST 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 458 LEDavvEIKNCKNQIKIRDREIEILTKEINKLELKISDFLDENEALRERV-GLEPKTMIDLTEF-----------RNSKH 525
Cdd:pfam10174 378 LAG---EIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVkSLQTDSSNTDTALttleealsekeRIIER 454
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 526 LKQQQYRaENQILLKEIESLEEERLDLKKKIRQMAQERGKRSA--------TSGLTTEDLNLTENISQGDRISERKLD-- 595
Cdd:pfam10174 455 LKEQRER-EDRERLEELESLKKENKDLKEKVSALQPELTEKESslidlkehASSLASSGLKKDSKLKSLEIAVEQKKEec 533
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 596 ------LLSLKNMSEAQSKNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVKG 669
Cdd:pfam10174 534 sklenqLKKAHNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQM 613
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767975376 670 GETSLIIPSLERLVNAIESKNAEGIFDASL--------HLKAQVDQLTGRNEELRQELRESRKEAINYSQQLA 734
Cdd:pfam10174 614 KEQNKKVANIKHGQQEMKKKGAQLLEEARRrednladnSQQLQLEELMGALEKTRQELDATKARLSSTQQSLA 686
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
1645-1961 |
3.39e-04 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 45.90 E-value: 3.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1645 KKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQS----QKESQCLKSELQAQKEANSRAPT 1720
Cdd:pfam09731 121 KSEQEKEKALEEVLKEAISKAESATAVAKEAKDDAIQAVKAHTDSLKEASDTAeisrEKATDSALQKAEALAEKLKEVIN 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1721 TTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVdrhtRELKTQVEDLNENLlk 1800
Cdd:pfam09731 201 LAKQSEEEAAPPLLDAAPETPPKLPEHLDNVEEKVEKAQSLAKLVDQYKELVASERIVFQ----QELVSIFPDIIPVL-- 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1801 lKEALKTSKNRENSLTD----NLNDLNNELQKKQKAYNKilREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQsLIEE 1876
Cdd:pfam09731 275 -KEDNLLSNDDLNSLIAhahrEIDQLSKKLAELKKREEK--HIERALEKQKEELDKLAEELSARLEEVRAADEAQ-LRLE 350
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1877 LQRKV--------KKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKD 1948
Cdd:pfam09731 351 FEREReeiresyeEKLRTELERQAEAHEEHLKDVLVEQEIELQREFLQDIKEKVEEERAGRLLKLNELLANLKGLEKATS 430
|
330
....*....|...
gi 767975376 1949 LFAKADKEKLTLQ 1961
Cdd:pfam09731 431 SHSEVEDENRKAQ 443
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1623-1979 |
3.44e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.21 E-value: 3.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1623 LAEMEQTVAEQD---DSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQK 1699
Cdd:TIGR02169 179 LEEVEENIERLDliiDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1700 ESQCLKSELQAQKEansrapttTMRNLVERLKsqlALKEKQQKALSRALLELRAEMtAAAEERIISATSQKEAHLNVQQI 1779
Cdd:TIGR02169 259 EISELEKRLEEIEQ--------LLEELNKKIK---DLGEEEQLRVKEKIGELEAEI-ASLERSIAEKERELEDAEERLAK 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1780 VDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIkrlts 1859
Cdd:TIGR02169 327 LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI----- 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1860 glqgKPLTDNKQSLIEELQRKVKKLEnQLEGKVEEVDLKPMKEKNAKEELIrwEEGKKWQAKIEGIRNKLKEKEGEVFTL 1939
Cdd:TIGR02169 402 ----NELKRELDRLQEELQRLSEELA-DLNAAIAGIEAKINELEEEKEDKA--LEIKKQEWKLEQLAADLSKYEQELYDL 474
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 767975376 1940 TKQLNTLKDLFAKADKEkltLQRKLKTTGMTVDQVLGIRA 1979
Cdd:TIGR02169 475 KEEYDRVEKELSKLQRE---LAEAEAQARASEERVRGGRA 511
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
36-277 |
5.03e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.83 E-value: 5.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 36 EVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGR-----DT 110
Cdd:TIGR02169 252 ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLakleaEI 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 111 RFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQ 190
Cdd:TIGR02169 332 DKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 191 KETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNV 270
Cdd:TIGR02169 412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491
|
....*..
gi 767975376 271 IDQLKKE 277
Cdd:TIGR02169 492 LAEAEAQ 498
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1671-1863 |
6.24e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 6.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1671 QLQENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRApTTTMRNL---VERLKSQLALKEKQQKALSRA 1747
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL-ARRIRALeqeLAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1748 LLELR---AEMTAAAEER--------IISATSQKEAhLNVQQIVDRHTRELKTQVEDLNEN---LLKLKEALKTSKNREN 1813
Cdd:COG4942 99 LEAQKeelAELLRALYRLgrqpplalLLSPEDFLDA-VRRLQYLKYLAPARREQAEELRADlaeLAALRAELEAERAELE 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 767975376 1814 SLTDNLNDLNNELQKKQKAYNKIL----REKEEIDQENDELKRQIKRLTSGLQG 1863
Cdd:COG4942 178 ALLAELEEERAALEALKAERQKLLarleKELAELAAELAELQQEAEELEALIAR 231
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
415-1255 |
6.32e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.35 E-value: 6.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 415 ILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESgvygLEDAVVEIKNCKNQIKIRDREIEILTKEINKLELKIS 494
Cdd:pfam02463 164 GSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKL----KEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERI 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 495 DFLDENEALRERVGL----EPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQERGKRSATS 570
Cdd:pfam02463 240 DLLQELLRDEQEEIEsskqEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKES 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 571 GLTTEDLNLTENISQGDRISERKLDLLSLKNMSEAQSKNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEG 650
Cdd:pfam02463 320 EKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELEL 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 651 MKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYS 730
Cdd:pfam02463 400 KSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 731 QQLAKANLKIDHLEKETSLLRQSEGSNVVFKGIDLPDGIAPSSASIINSQNEYLIHLLQELEnkekKLKNLEDSLEDYNR 810
Cdd:pfam02463 480 VKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENY----KVAISTAVIVEVSA 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 811 KFAVIRHQQSLLYKEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITVLQ 890
Cdd:pfam02463 556 TADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELT 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 891 VNEKSLIRQYTTLVELERQLRKENEKQK-NELLSMEAEVCEKIGCLQRFKEMAIFKIAALQKVVDNSVSLSELELANKQY 969
Cdd:pfam02463 636 KLKESAKAKESGLRKGVSLEEGLAEKSEvKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKL 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 970 NELTAKYRDILQKDNMLVQRTSNLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQETKLGNESSMDKAKKSITN 1049
Cdd:pfam02463 716 KLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEK 795
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1050 SDIVSISKKITMLEMKELNERQRA-----EHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDELAD 1124
Cdd:pfam02463 796 LKAQEEELRALEEELKEEAELLEEeqlliEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLK 875
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1125 SVSKAVSDADRQRILELEKNEMELKVEVSKLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLH 1204
Cdd:pfam02463 876 EEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNK 955
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|.
gi 767975376 1205 QHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLE 1255
Cdd:pfam02463 956 EEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKK 1006
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
970-1310 |
7.89e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 44.73 E-value: 7.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 970 NELTAKYRDILQKDNMLVQRTSNLEHLECENISLKEQVESINKELEiTKEKLHTIEQAWEQEtklgnessMDKakksitN 1049
Cdd:pfam17380 268 NEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVE-RRRKLEEAEKARQAE--------MDR------Q 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1050 SDIVSISKKITMLEMKELnERQRAEHCQKMYEHLRtslkqMEERNFELEtKFAELTKINLDAQKVEQMLRDELADSVSKA 1129
Cdd:pfam17380 333 AAIYAEQERMAMEREREL-ERIRQEERKRELERIR-----QEEIAMEIS-RMRELERLQMERQQKNERVRQELEAARKVK 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1130 VSDADRQRILELEKNEMEL------KVEVSKLREISDIARRQVEILNAQQQSRDKEVESLRMQlldyQAQSDEKSLIAKL 1203
Cdd:pfam17380 406 ILEEERQRKIQQQKVEMEQiraeqeEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQ----EEERKRKKLELEK 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1204 HQHNVSLQLSEATALGKLESITSKLQKMEAYNLR--LEQKLDEKEQALYYArlEGRNRAKHLRQTIQSL--RRQFSGALP 1279
Cdd:pfam17380 482 EKRDRKRAEEQRRKILEKELEERKQAMIEEERKRklLEKEMEERQKAIYEE--ERRREAEEERRKQQEMeeRRRIQEQMR 559
|
330 340 350
....*....|....*....|....*....|.
gi 767975376 1280 LAQQEKFSKTMIQLQNDKLKIMQEMKNSQQE 1310
Cdd:pfam17380 560 KATEERSRLEAMEREREMMRQIVESEKARAE 590
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
106-373 |
1.29e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.29 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 106 GGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEK-EKKVNEQLALRNE------EAENENSKLRRENKRLKKKNEQLCQ 178
Cdd:TIGR02169 658 GSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSlQSELRRIENRLDElsqelsDASRKIGEIEKEIEQLEQEEEKLKE 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 179 DIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTL--TEANEKIEVQNQEMRKnLEESVQEMEKMTDE 256
Cdd:TIGR02169 738 RLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLeaRLSHSRIPEIQAELSK-LEEEVSRIEARLRE 816
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 257 YNRMKAIVHQTDNVIDQLKKEndhyqlqVQELTDLLKSKNEEddpimvaVNAKVEEWKLILSSKDDEIIEYQQMLHNLRE 336
Cdd:TIGR02169 817 IEQKLNRLTLEKEYLEKEIQE-------LQEQRIDLKEQIKS-------IEKEIENLNGKKEELEEELEELEAALRDLES 882
|
250 260 270
....*....|....*....|....*....|....*....
gi 767975376 337 KLKNAQLDAD--KSNVMALQQGIQERDSQIKMLTEQVEQ 373
Cdd:TIGR02169 883 RLGDLKKERDelEAQLRELERKIEELEAQIEKKRKRLSE 921
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1726-2455 |
1.29e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 44.28 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1726 LVERLKSQLALKEKQQKALSRaLLELRAEMTAAaeERIISATSQKEAHLNVQQiVDRHTRELKTQVEDLNENLLKLKEAL 1805
Cdd:TIGR02168 194 ILNELERQLKSLERQAEKAER-YKELKAELREL--ELALLVLRLEELREELEE-LQEELKEAEEELEELTAELQELEEKL 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1806 KTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQgkpltdNKQSLIEELQRKVKKLE 1885
Cdd:TIGR02168 270 EELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLE------ELESKLDELAEELAELE 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1886 NQLEGKVEEVDLKPMKEKNAKEELIRWEEG-KKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKD---------------- 1948
Cdd:TIGR02168 344 EKLEELKEELESLEAELEELEAELEELESRlEELEEQLETLRSKVAQLELQIASLNNEIERLEArlerledrrerlqqei 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1949 ---LFAKADKEKLTLQRKLKTTGMTVDQVLG-IRALESEKELEELKKRNLDLENDILYMRAHQALPRDSVVEDLHLQNRY 2024
Cdd:TIGR02168 424 eelLKKLEEAELKELQAELEELEEELEELQEeLERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2025 LQEKLHALEKQFSKDTYSKPSQNQISGIESDDHCQREQELQK--ENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEM 2102
Cdd:TIGR02168 504 FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGrlQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKG 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2103 CEFLKKEKAEVQRKLGHVRGSGRSGKTIPELEKTIGLM---KKVVEKVQRENEQLKK----------------ASGILT- 2162
Cdd:TIGR02168 584 TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggVLVVDDLDNALELAKKlrpgyrivtldgdlvrPGGVITg 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2163 -SEKMANIEQENEKLKAELEKLKAHLGHQLsmhyesktkgtEKIIAENERLRKELKKETDAAEKLRIAKNNLEILNEKMT 2241
Cdd:TIGR02168 664 gSAKTNSSILERRREIEELEEKIEELEEKI-----------AELEKALAELRKELEELEEELEQLRKELEELSRQISALR 732
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2242 VQLEETGKRLQFAESRGPQLEGADSKSWKSIVVTRmyetklkeletdiAKKNQSITDLKQLVKEATEREQKVNKYNEDLE 2321
Cdd:TIGR02168 733 KDLARLEAEVEQLEERIAQLSKELTELEAEIEELE-------------ERLEEAEEELAEAEAEIEELEAQIEQLKEELK 799
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2322 QQIKILKHVpEGAETEqgLKRELQVLRLANHQLDKEKAELIHQIEANKDQSGAESTipDADQLKEKIKDLETQLkmSDLE 2401
Cdd:TIGR02168 800 ALREALDEL-RAELTL--LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE--DIESLAAEIEELEELI--EELE 872
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....
gi 767975376 2402 KQHLKEEIKKLkkelenfdpSFFEEIEDLKYNYKEEVKKNILLEEKVKKLSEQL 2455
Cdd:TIGR02168 873 SELEALLNERA---------SLEEALALLRSELEELSEELRELESKRSELRREL 917
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1626-1846 |
1.69e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.85 E-value: 1.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1626 MEQTVAEQDDSLSSLLVKLKKVSQDLER-QREITELKVK-------EFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQS 1697
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEaEAALEEFRQKnglvdlsEEAKLLLQQLSELESQLAEARAELAEAEARLAAL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1698 QKEsqcLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMtAAAEERIISATSQKEAHLNVQ 1777
Cdd:COG3206 246 RAQ---LGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQI-AALRAQLQQEAQRILASLEAE 321
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767975376 1778 QivdrhtRELKTQVEDLNENLLKLKEALKTSKNREnsltDNLNDLNNELQKKQKAYNKILREKEEIDQE 1846
Cdd:COG3206 322 L------EALQAREASLQAQLAQLEARLAELPELE----AELRRLEREVEVARELYESLLQRLEEARLA 380
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
130-176 |
1.75e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 43.28 E-value: 1.75e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 767975376 130 ELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQL 176
Cdd:PRK03992 2 RLEALEERNSELEEQIRQLELKLRDLEAENEKLERELERLKSELEKL 48
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
703-1581 |
2.42e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.51 E-value: 2.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 703 AQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRqsegsnvvfkgidlpdgiapssaSIINSQNE 782
Cdd:TIGR02168 225 LELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR-----------------------LEVSELEE 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 783 YLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQsllyKEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEYN 862
Cdd:TIGR02168 282 EIEELQKELYALANEISRLEQQKQILRERLANLERQL----EELEAQLEELESKLDELAEELAELEEKLEELKEELESLE 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 863 NLLNALQMDSDEMKKILAEnsrkitvlqvneksLIRQYTTLVELERQLRKENEKQKNELLSMEAEvcekigclqrfkema 942
Cdd:TIGR02168 358 AELEELEAELEELESRLEE--------------LEEQLETLRSKVAQLELQIASLNNEIERLEAR--------------- 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 943 ifkIAALQKVVDNSVSLSELELANKQYNELTAKYRDILQKDNMLVQRTSNLEHLECENISLKEQVESINKELEITKEKLH 1022
Cdd:TIGR02168 409 ---LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1023 TIEQAWEQ-ETKLGNESSMDKAKKSITN------------SDIVSISKK------------ITMLEMKELNERQRAEHCQ 1077
Cdd:TIGR02168 486 QLQARLDSlERLQENLEGFSEGVKALLKnqsglsgilgvlSELISVDEGyeaaieaalggrLQAVVVENLNAAKKAIAFL 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1078 KMYEHLRTSlkqmeernfeletkFAELTKINLDAQKVEQMLRDELADSVskavsdadRQRILELEKNEMELKVEVSKLRE 1157
Cdd:TIGR02168 566 KQNELGRVT--------------FLPLDSIKGTEIQGNDREILKNIEGF--------LGVAKDLVKFDPKLRKALSYLLG 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1158 ISDIARRqveILNAQQQSRDKEVESLRMQLLDYQAQSDekSLIAKLHQHNVSLQLSEATALGKLEsitSKLQKMEAYNLR 1237
Cdd:TIGR02168 624 GVLVVDD---LDNALELAKKLRPGYRIVTLDGDLVRPG--GVITGGSAKTNSSILERRREIEELE---EKIEELEEKIAE 695
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1238 LEQKLDEKEQALYyarlEGRNRAKHLRQTIQSLRRQFSGALplaqqekfsktmIQLQNDKLKIMQEMKNSQQEHRNMENK 1317
Cdd:TIGR02168 696 LEKALAELRKELE----ELEEELEQLRKELEELSRQISALR------------KDLARLEAEVEQLEERIAQLSKELTEL 759
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1318 TLEMELKLKGLEELISTLKDTKGaqkvinwhmKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQqn 1397
Cdd:TIGR02168 760 EAEIEELEERLEEAEEELAEAEA---------EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES-- 828
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1398 kfHEERQMAWDQREVDLERQLDifdrqqneilNAAQKFEEATGSIpdpslplpNQLEIALRKIKENIRIILETRAtckSL 1477
Cdd:TIGR02168 829 --LERRIAATERRLEDLEEQIE----------ELSEDIESLAAEI--------EELEELIEELESELEALLNERA---SL 885
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1478 EEKLKEKESALRLAEQNILSRDKVINELRlrlpatAEREKLIAELGRKEMEpkshhtLKIAHQTIANMQARLNQK----E 1553
Cdd:TIGR02168 886 EEALALLRSELEELSEELRELESKRSELR------RELEELREKLAQLELR------LEGLEVRIDNLQERLSEEysltL 953
|
890 900
....*....|....*....|....*...
gi 767975376 1554 EVLKKYQRLLEKAREEQREIVKKHEEDL 1581
Cdd:TIGR02168 954 EEAEALENKIEDDEEEARRRLKRLENKI 981
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
35-200 |
2.86e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 42.92 E-value: 2.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 35 VEVNELKSEkqenVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMaqqsaggrdtrfLR 114
Cdd:COG2433 363 VDRDEVKAR----VIRGLSIEEALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVER------------LE 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 115 NEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAenenSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETL 194
Cdd:COG2433 427 AEVEELEAELEEKDERIERLERELSEARSEERREIRKDREI----SRLDREIERLERELEEERERIEELKRKLERLKELW 502
|
....*..
gi 767975376 195 -LSRRGE 200
Cdd:COG2433 503 kLEHSGE 509
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
416-640 |
2.93e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.08 E-value: 2.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 416 LKEKTKEAERTAELAEADAREKDKELVEALKRLKDY--ESGVYGLEDavveikncknQIKIRDREIEILTKEINKLELKI 493
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFrqKNGLVDLSE----------EAKLLLQQLSELESQLAEARAEL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 494 SDFLDENEALRERVGLEPKTMIDLTEFRNSKHLKQQQYRAENQI--LLK-------EIESLEEERLDLKKKIRQMAQE-- 562
Cdd:COG3206 236 AEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELaeLSArytpnhpDVIALRAQIAALRAQLQQEAQRil 315
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767975376 563 RGKRSATSGLTTEDLNLTENISQgdrISERkldllsLKNMSEAQskneflsRELIEKERDLERSRTVIAKFQNKLKEL 640
Cdd:COG3206 316 ASLEAELEALQAREASLQAQLAQ---LEAR------LAELPELE-------AELRRLEREVEVARELYESLLQRLEEA 377
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
1446-1895 |
3.19e-03 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 43.12 E-value: 3.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1446 SLPLPNQLEIALRKIKEN-----IRIILETRATCKSLEEKlkekesalRLAEQNILSRDKVINELrlrlpataerEKLIA 1520
Cdd:PRK10929 21 TAPDEKQITQELEQAKAAktpaqAEIVEALQSALNWLEER--------KGSLERAKQYQQVIDNF----------PKLSA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1521 ELgRKEMEPKSHHTLKI-AHQTIANmqarLNQkeEVLKKYQRLLEKAREEQreivkkHEEDlhilhhRLELQADsSLNKF 1599
Cdd:PRK10929 83 EL-RQQLNNERDEPRSVpPNMSTDA----LEQ--EILQVSSQLLEKSRQAQ------QEQD------RAREISD-SLSQL 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1600 KQTAWDLMKQsptpvptnkhfirLAEMEQTVAEQDDSLSSLlvklkKVSQDLERQREITELKVKEFENIKLQLQENHEDE 1679
Cdd:PRK10929 143 PQQQTEARRQ-------------LNEIERRLQTLGTPNTPL-----AQAQLTALQAESAALKALVDELELAQLSANNRQE 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1680 VKKVKAEVEDLKYllDQSQKESQCLKSEL--QAQKEANSRAPTTTM-----RNLVERLKSQLalkeKQQKALSRALLELR 1752
Cdd:PRK10929 205 LARLRSELAKKRS--QQLDAYLQALRNQLnsQRQREAERALESTELlaeqsGDLPKSIVAQF----KINRELSQALNQQA 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1753 AEMTA-AAEERiiSATSQKeahLNVQQIVDRhTRE--------------LKTQVEDLNE---------NLLKLK-EALKT 1807
Cdd:PRK10929 279 QRMDLiASQQR--QAASQT---LQVRQALNT-LREqsqwlgvsnalgeaLRAQVARLPEmpkpqqldtEMAQLRvQRLRY 352
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1808 SK--NRENSLTDNLNDLNNELQKKQkayNKILrekeeidqeNDELKRQIKRLTSGLQGkpltdnKQSLIEELQrKVKKLE 1885
Cdd:PRK10929 353 EDllNKQPQLRQIRQADGQPLTAEQ---NRIL---------DAQLRTQRELLNSLLSG------GDTLILELT-KLKVAN 413
|
490
....*....|
gi 767975376 1886 NQLEGKVEEV 1895
Cdd:PRK10929 414 SQLEDALKEV 423
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1756-1964 |
3.56e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.12 E-value: 3.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1756 TAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNK 1835
Cdd:COG3883 11 PAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1836 ILREKEEIDQENDELK-----RQIKRLTSGLQG-KPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDlkpmKEKNAKEEL 1909
Cdd:COG3883 91 RARALYRSGGSVSYLDvllgsESFSDFLDRLSAlSKIADADADLLEELKADKAELEAKKAELEAKLA----ELEALKAEL 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 767975376 1910 irweegkkwQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKL 1964
Cdd:COG3883 167 ---------EAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAA 212
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
1628-1896 |
3.79e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 42.31 E-value: 3.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1628 QTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKefeniklqLQENHEDEVKKV-KAEVEDLKYLLDQSQKESQCLKS 1706
Cdd:PHA02562 163 SVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIK--------TYNKNIEEQRKKnGENIARKQNKYDELVEEAKTIKA 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1707 ELqaqkeansraptttmrnlvERLKSQLALKEKQQKALSRALLELRAEMTAAAEERiisATSQKEAHLN---------VQ 1777
Cdd:PHA02562 235 EI-------------------EELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKI---EQFQKVIKMYekggvcptcTQ 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1778 QIVDrhTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRL 1857
Cdd:PHA02562 293 QISE--GPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEEL 370
|
250 260 270
....*....|....*....|....*....|....*....
gi 767975376 1858 TSGlqgkplTDNKQSLIEELQRKVKKLENQLEGKVEEVD 1896
Cdd:PHA02562 371 QAE------FVDNAEELAKLQDELDKIVKTKSELVKEKY 403
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1622-1865 |
4.11e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 4.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1622 RLAEMEQTVAEQDDSLSSLLVKLKKVSQDL----ERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQS 1697
Cdd:COG4913 611 KLAALEAELAELEEELAEAEERLEALEAELdalqERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAAL 690
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1698 QKESQCLKSELQAQKEANSRApTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIiSATSQKEAHLNVQ 1777
Cdd:COG4913 691 EEQLEELEAELEELEEELDEL-KGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERF-AAALGDAVERELR 768
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1778 QIVDRHTRELKTQVEDLNENLLKL-KEALKTSKNRENSLTDNLNDL-----------NNELQKKQKAYNKILREKE---- 1841
Cdd:COG4913 769 ENLEERIDALRARLNRAEEELERAmRAFNREWPAETADLDADLESLpeylalldrleEDGLPEYEERFKELLNENSiefv 848
|
250 260
....*....|....*....|....*....
gi 767975376 1842 -----EIDQENDELKRQIKRLTSGLQGKP 1865
Cdd:COG4913 849 adllsKLRRAIREIKERIDPLNDSLKRIP 877
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1002-1569 |
4.54e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.62 E-value: 4.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1002 SLKEQVE------SINKELEITK--EKLHTIEQAWEQETKLGNESSMDKAKKSITNSDIVSISKKITMLEMKELNERQRA 1073
Cdd:COG1196 204 PLERQAEkaeryrELKEELKELEaeLLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1074 EHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDELADsvskavsdaDRQRILELEKNEMELKVEVS 1153
Cdd:COG1196 284 EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEE---------LEEELEELEEELEEAEEELE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1154 KLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDY-QAQSDEKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKME 1232
Cdd:COG1196 355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAlRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1233 AYNLRLEQKLDE-KEqalyyARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEmknsQQEH 1311
Cdd:COG1196 435 EEEEEEEEALEEaAE-----EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA----DYEG 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1312 RNMENKTLEMELKLKGLEELISTL------------------------KDTKGAQKVINWHMKIEELRLQELKLNRElvk 1367
Cdd:COG1196 506 FLEGVKAALLLAGLRGLAGAVAVLigveaayeaaleaalaaalqnivvEDDEVAAAAIEYLKAAKAGRATFLPLDKI--- 582
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1368 DKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSl 1447
Cdd:COG1196 583 RARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS- 661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1448 plpnqleIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAEREKLIAELGRKEM 1527
Cdd:COG1196 662 -------LTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 767975376 1528 EPKSHHTLKIAHQTIANMQARL--NQKEEVLKKYQRLLEKAREE 1569
Cdd:COG1196 735 EELLEELLEEEELLEEEALEELpePPDLEELERELERLEREIEA 778
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
149-394 |
4.56e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.06 E-value: 4.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 149 ALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNyeliqylDEIQTLTEA 228
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALE-------AELAELEKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 229 NEKIEVQNQEMRKNLEESVQEMEKMtDEYNRMKAIVHQTDnvidqlkkendhyQLQVQELTDLLKSKNEEDDPIMVAVNA 308
Cdd:COG4942 92 IAELRAELEAQKEELAELLRALYRL-GRQPPLALLLSPED-------------FLDAVRRLQYLKYLAPARREQAEELRA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 309 KVEEwkliLSSKDDEIIEYQQMLHNLREKLKNAQLdadksnvmALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDL 388
Cdd:COG4942 158 DLAE----LAALRAELEAERAELEALLAELEEERA--------ALEALKAERQKLLARLEKELAELAAELAELQQEAEEL 225
|
....*.
gi 767975376 389 KNELQR 394
Cdd:COG4942 226 EALIAR 231
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
1838-1979 |
4.84e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 42.15 E-value: 4.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1838 REKEEIDQENDELKRQIKRLtsglqgkpltdnkQSLIEELQRKVKKLENQLEGKVEEVD-----LKPMKeKNAKEELIRW 1912
Cdd:COG2433 399 REKEHEERELTEEEEEIRRL-------------EEQVERLEAEVEELEAELEEKDERIErlereLSEAR-SEERREIRKD 464
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767975376 1913 EEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKL----KTTGMTVDQVLGIRA 1979
Cdd:COG2433 465 REISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGELVPVKVVekftKEAIRRLEEEYGLKE 535
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1630-2395 |
5.37e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 42.36 E-value: 5.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1630 VAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFEniKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKEsqclksELQ 1709
Cdd:TIGR02169 165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLE--RLRREREKAERYQALLKEKREYEGYELLKEKE------ALE 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1710 AQKEAnSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRELKT 1789
Cdd:TIGR02169 237 RQKEA-IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKER 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1790 QVEDLNENLLKLKEALKTSKNRENSLTDNLND-------LNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQ 1862
Cdd:TIGR02169 316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEerkrrdkLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1863 G-----KPLTDNKQSLIEELQRKVKKLENqLEGKVEEVDLKPMKEKNAKEELIrwEEGKKWQAKIEGIRNKLKEKEGEVF 1937
Cdd:TIGR02169 396 KlkreiNELKRELDRLQEELQRLSEELAD-LNAAIAGIEAKINELEEEKEDKA--LEIKKQEWKLEQLAADLSKYEQELY 472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1938 TLTKQLNTLKDLFAKADKEkltLQRKLKTTGMTVDQVLGIRALESEKELEEL--------------------------KK 1991
Cdd:TIGR02169 473 DLKEEYDRVEKELSKLQRE---LAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtvaqlgsvgeryataievaagnRL 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1992 RNLDLEND------ILYMRAHQA-----LPRDSVvEDLHLQNRYLQEK--------LHALEKQFSKDTYSKpsqNQISGI 2052
Cdd:TIGR02169 550 NNVVVEDDavakeaIELLKRRKAgratfLPLNKM-RDERRDLSILSEDgvigfavdLVEFDPKYEPAFKYV---FGDTLV 625
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2053 ESDDHCQREQELQKENLKLSSENIE---------------LKFQLEQANKdLPRLKNQVRDLKEMCEFLKKEKAEVQRKL 2117
Cdd:TIGR02169 626 VEDIEAARRLMGKYRMVTLEGELFEksgamtggsraprggILFSRSEPAE-LQRLRERLEGLKRELSSLQSELRRIENRL 704
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2118 GHVRGS-GRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMANI-------------EQENEKLKAELEKL 2183
Cdd:TIGR02169 705 DELSQElSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKselkelearieelEEDLHKLEEALNDL 784
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2184 KAHLGHQLSMHYESKTKGTEKIIAENER----LRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQFAESRGP 2259
Cdd:TIGR02169 785 EARLSHSRIPEIQAELSKLEEEVSRIEArlreIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE 864
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2260 QLEgadskswksivvtrmyeTKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHVPEgaeteqG 2339
Cdd:TIGR02169 865 ELE-----------------EELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS------E 921
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*.
gi 767975376 2340 LKRELQVLRLANHQLDKEKAELIHQIEAnkdqsgaestIPDADQLKEKIKDLETQL 2395
Cdd:TIGR02169 922 LKAKLEALEEELSEIEDPKGEDEEIPEE----------ELSLEDVQAELQRVEEEI 967
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1553-2108 |
6.11e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.88 E-value: 6.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1553 EEVLKKYQRLLEKAREEQREIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMK-QSPTPVPTNKHFIRLAEMEQTVA 1631
Cdd:TIGR00618 303 TQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRdAHEVATSIREISCQQHTLTQHIH 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1632 EQDDSLSSLLVKLKKVSQDLERQREitelkvkEFENIKLQLQENHEDEVKKVKAEVE---DLKYLLDQSQKESQCLKSEL 1708
Cdd:TIGR00618 383 TLQQQKTTLTQKLQSLCKELDILQR-------EQATIDTRTSAFRDLQGQLAHAKKQqelQQRYAELCAAAITCTAQCEK 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1709 QAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLN-------VQQIVD 1781
Cdd:TIGR00618 456 LEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNpgpltrrMQRGEQ 535
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1782 RHtRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGL 1861
Cdd:TIGR00618 536 TY-AQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQ 614
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1862 QGKPL----TDNKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKKW---QAKIEGIRNKLKEKEG 1934
Cdd:TIGR00618 615 HALLRklqpEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLasrQLALQKMQSEKEQLTY 694
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1935 EVFTLTKQLNTLKDL---FAKADKEKLTLQRKLKTTGMTVDQVLGIRALESEKELEELKKRNLDLENDilYMRAHQALPR 2011
Cdd:TIGR00618 695 WKEMLAQCQTLLRELethIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEA--HFNNNEEVTA 772
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2012 D--------SVVEDLHLQNRYLQEKLHALEKQFSKDTYSKPSQNQISGIESDDHCQREQELQKENLKLSSENIELKFQLE 2083
Cdd:TIGR00618 773 AlqtgaelsHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLL 852
|
570 580
....*....|....*....|....*
gi 767975376 2084 QANKDLPRLKNQVRDLKEMCEFLKK 2108
Cdd:TIGR00618 853 KYEECSKQLAQLTQEQAKIIQLSDK 877
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1784-2412 |
6.76e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.85 E-value: 6.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1784 TRELKTQVEDLN------ENLLKLKEALKTSKNRENSLtdNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRL 1857
Cdd:COG1196 195 LGELERQLEPLErqaekaERYRELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1858 TSGLQgkpltdNKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWE-EGKKWQAKIEGIRNKLKEKEGEV 1936
Cdd:COG1196 273 RLELE------ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEeELAELEEELEELEEELEELEEEL 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1937 FTLTKQLNTLKDLFAKADKEKLTLQRKLkttgmtvdqvlgiraLESEKELEELKKRNLDLENDILYMRAHQALPRDSVVE 2016
Cdd:COG1196 347 EEAEEELEEAEAELAEAEEALLEAEAEL---------------AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEA 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2017 DLHLQNRYLQEKLHALEKQfskdtyskpsqnQISGIESDDHCQREQELQKENLKLSSENIELKFQLEQANKDLPRLKNQV 2096
Cdd:COG1196 412 LLERLERLEEELEELEEAL------------AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2097 RDLKEMCEFLKKEKAEVQRKLGHVRGSGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMANIEQENEKL 2176
Cdd:COG1196 480 AELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVA 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2177 KAELEKLKAHLGHQlsmhyesktkgtekiiAENERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQfAES 2256
Cdd:COG1196 560 AAAIEYLKAAKAGR----------------ATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG-DTL 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2257 RGPQLEGADSKSWKSIVVTRMYETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKyNEDLEQQIKILKHVPEGAET 2336
Cdd:COG1196 623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL-EELAERLAEEELELEEALLA 701
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767975376 2337 EQGLKRELQVLRLANHQLDKEKAELIHQIEANKDQSGAESTIPDADQLKEKIKDLETQLKMSDLEKQhlkeeIKKL 2412
Cdd:COG1196 702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE-----LERL 772
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1704-2469 |
6.99e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.88 E-value: 6.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1704 LKSELQAQKEANSRAPTTTMRNLVERLKSQLALK-EKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDR 1782
Cdd:pfam02463 200 LKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKlNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEK 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1783 HTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQ 1862
Cdd:pfam02463 280 EKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEE 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1863 GKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKPM----KEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVFT 1938
Cdd:pfam02463 360 ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELelksEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESI 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1939 LTKQ----LNTLKDLFAKADKEKLTLQRKLKTTGMTVDQVLGIRALESEKELEELKKRNLDLENDILYMRAHQALPRDSV 2014
Cdd:pfam02463 440 ELKQgkltEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDG 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2015 VEDLHLQNRYLQEKLH-ALEKQFSKDTYSKPSQNQISGIESDDHCQREQELQKENLKLSSENIELKFQLEQANKDLP--- 2090
Cdd:pfam02463 520 VGGRIISAHGRLGDLGvAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVlei 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2091 ------RLKNQVRDLKEMCEFLKKEKAEVQRKLGHVRGSGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSE 2164
Cdd:pfam02463 600 dpilnlAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2165 KMANIEQENEKLKAELEKLKAHLGHQLSMHYESKTKGTEKIIAENERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQL 2244
Cdd:pfam02463 680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2245 EETGKRLQFAESRGPQLEGADSKSWKSIVVTRMYETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQI 2324
Cdd:pfam02463 760 EEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELA 839
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 2325 KILKHVPEGAETEQGLKRELQVLRLANHQLDKEKAELIHQIEANKDQSGAESTipDADQLKEKIKDLETQLKMSDLEKQH 2404
Cdd:pfam02463 840 LELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKE--EKEKEEKKELEEESQKLNLLEEKEN 917
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767975376 2405 LKEEIKKLKKELENFDPSFFEEIEDLKYNYKEEVKKNILLEEKVKKLSEQLGVELTSPVA-ASEEF 2469
Cdd:pfam02463 918 EIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLmAIEEF 983
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1293-1700 |
7.15e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.98 E-value: 7.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1293 LQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDtkgaqkvinwhmKIEELRLQELKLNRELVKDKEEI 1372
Cdd:TIGR02169 693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE------------RLEELEEDLSSLEQEIENVKSEL 760
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1373 KYLNNIISEYERTISSLEEEIvqqnkfheerqmawdqreVDLERQLDifDRQQNEILNAAQKFEEATGSIpdpslplpnq 1452
Cdd:TIGR02169 761 KELEARIEELEEDLHKLEEAL------------------NDLEARLS--HSRIPEIQAELSKLEEEVSRI---------- 810
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1453 leialRKIKENIRIILETRATCK-SLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAERekliaelgrkemepks 1531
Cdd:TIGR02169 811 -----EARLREIEQKLNRLTLEKeYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE---------------- 869
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1532 hhtlkiahqtIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEdlhilhhrlelqADSSLNKFKQTAWDLMKQSP 1611
Cdd:TIGR02169 870 ----------LEELEAALRDLESRLGDLKKERDELEAQLRELERKIEE------------LEAQIEKKRKRLSELKAKLE 927
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1612 TPVPTNKHFIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQEnHEDEVKKVKAEVEDLK 1691
Cdd:TIGR02169 928 ALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDE-LKEKRAKLEEERKAIL 1006
|
....*....
gi 767975376 1692 YLLDQSQKE 1700
Cdd:TIGR02169 1007 ERIEEYEKK 1015
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1782-1933 |
8.00e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 41.74 E-value: 8.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1782 RHTRELKTQVEDLNENLLKLKEALKtskNRENSLtdnlndlnneLQKKQKAYNKILRE-KEEIDQENDELKRQIKRLTSG 1860
Cdd:PRK00409 537 EEAEALLKEAEKLKEELEEKKEKLQ---EEEDKL----------LEEAEKEAQQAIKEaKKEADEIIKELRQLQKGGYAS 603
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767975376 1861 LQGKPLTDNKQSLIEELQRKVKKL----ENQLEGKV-EEVDLKPMkekNAKEELIRWEEGKKWQAKIEGIRNKLKEKE 1933
Cdd:PRK00409 604 VKAHELIEARKRLNKANEKKEKKKkkqkEKQEELKVgDEVKYLSL---GQKGEVLSIPDDKEAIVQAGIMKMKVPLSD 678
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1731-1894 |
8.27e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.44 E-value: 8.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1731 KSQLALKEKQQKALSRALLELRAEMTAAAEERIiSATSQKEAHLNVQQI---------VDRHTRELKTQVEDLNENLLKL 1801
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELD-ALQERREALQRLAEYswdeidvasAEREIAELEAELERLDASSDDL 687
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1802 KEalktsknrensLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKP---------------- 1865
Cdd:COG4913 688 AA-----------LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEdlarlelralleerfa 756
|
170 180 190
....*....|....*....|....*....|....*....
gi 767975376 1866 ----------LTDNKQSLIEELQRKVKKLENQLEGKVEE 1894
Cdd:COG4913 757 aalgdavereLRENLEERIDALRARLNRAEEELERAMRA 795
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
874-1402 |
8.34e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.59 E-value: 8.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 874 EMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRK------ENEKQKNELLSMEAEVCEKIGCLQRFKEMAIFKIA 947
Cdd:PRK03918 197 EKEKELEEVLREINEISSELPELREELEKLEKEVKELEElkeeieELEKELESLEGSKRKLEEKIRELEERIEELKKEIE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 948 ALQKVVDNsvsLSELELANKQYNELTAKYRDILQKDNMLVQRTSNLEHLECENISLKEQVESINKELEITKEKLHTIEQA 1027
Cdd:PRK03918 277 ELEEKVKE---LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKR 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1028 WEQETKLGNESSMDKAKKsitnSDIVSISKKITMLEMKELNE-----RQRAEHCQKMYEHLRTSLKQMEERNFELETKFA 1102
Cdd:PRK03918 354 LEELEERHELYEEAKAKK----EELERLKKRLTGLTPEKLEKeleelEKAKEEIEEEISKITARIGELKKEIKELKKAIE 429
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1103 ELTKIN----LDAQKVEQMLRDELADSVSKAVSDAdRQRILELEKNEMELKVEVSKLREISDIARRQVEILNAQQQSRDK 1178
Cdd:PRK03918 430 ELKKAKgkcpVCGRELTEEHRKELLEEYTAELKRI-EKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKEL 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1179 EVESLRMQLLDYQAQSDEKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALyyaRLEGRN 1258
Cdd:PRK03918 509 EEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKEL---EELGFE 585
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1259 RAKHLRQTIQSLrrqfsgalplaqqEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDT 1338
Cdd:PRK03918 586 SVEELEERLKEL-------------EPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEEL 652
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767975376 1339 kgaqKVINWHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEE 1402
Cdd:PRK03918 653 ----EKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKE 712
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
1096-1192 |
8.82e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 40.72 E-value: 8.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 1096 ELETKFAELT-KINLDAQKVEQmLRDELAD-SVSKAVSDADRQRIL-----------ELEKNEMELKVEVSKLREISDIA 1162
Cdd:PRK09039 57 RLNSQIAELAdLLSLERQGNQD-LQDSVANlRASLSAAEAERSRLQallaelagagaAAEGRAGELAQELDSEKQVSARA 135
|
90 100 110
....*....|....*....|....*....|
gi 767975376 1163 RRQVEILNAQqqsrdkeVESLRMQLLDYQA 1192
Cdd:PRK09039 136 LAQVELLNQQ-------IAALRRQLAALEA 158
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
129-989 |
9.87e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.50 E-value: 9.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 129 RELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQidsQKETLLSRRGEDSDYRSQL 208
Cdd:pfam02463 166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEE---EYLLYLDYLKLNEERIDLL 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 209 SKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVhQTDNVIDQLKKENDHYQLQVQEL 288
Cdd:pfam02463 243 QELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEEL-KSELLKLERRKVDDEEKLKESEK 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 289 TDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKSNVMALQQGIQERDSQIKMLT 368
Cdd:pfam02463 322 EKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 369 EQVEQYTKEMEKNTCIIEDLKNELQR------NKGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELV 442
Cdd:pfam02463 402 EEEKEAQLLLELARQLEDLLKEEKKEeleileEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 443 EALKRLK----DYESGVYGLEDAVVEIKNCKNQIKIRDREIEILTKEINKLELKISDFLDENEALRERVGLEPKTMIDLT 518
Cdd:pfam02463 482 LQEQLELllsrQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 519 EFRNSKHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQERGKRSATSGLTTEDLNLTENISQGDRISERKLDLLS 598
Cdd:pfam02463 562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 599 LKNMSEAQSKNEFLSRELIEKERDlerSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPS 678
Cdd:pfam02463 642 KAKESGLRKGVSLEEGLAEKSEVK---ASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLE 718
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 679 LERLVNAIESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQSEGSNV 758
Cdd:pfam02463 719 AEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKA 798
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 759 VFKgidlpdgiapsSASIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRK--FAVIRHQQSLLYKEYLSEKETWKTE 836
Cdd:pfam02463 799 QEE-----------ELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALelKEEQKLEKLAEEELERLEEEITKEE 867
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767975376 837 SKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKENEK 916
Cdd:pfam02463 868 LLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADE 947
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767975376 917 QKNELLSMEAEVCEKIGCLQRFKEMAIFKIAALQKVVDNSVSLSELELankQYNELTAKYRDILQKDNMLVQR 989
Cdd:pfam02463 948 KEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDEL---EKERLEEEKKKLIRAIIEETCQ 1017
|
|
| |
